association	dataset	threshold value	standardized value
mRNA 3'-end processing	GO Biological Process Annotations 2023	1.0	null
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5102
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8823
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44672
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00161
paraseptal subpallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06921
positive regulation of cell cycle G1/S phase transition	GO Biological Process Annotations 2025	1.0	null
GSE248858_4_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1212
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845899
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.6032
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52127
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30644
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09216
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70709
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.74524
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01962
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18209
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03025
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88174
SCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06038
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
S0-EE-YNU4_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250845
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46976
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32677
GSE190384,GSE190386_6_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99266
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68412
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02606
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0882
Prostate adenocarcinoma_PRAD_TCGA-G9-6343-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.77874
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5964_LTO1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.636494
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01739
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-47-YZ27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312549
PEMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22992
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855002
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21952
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08658
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35155
Azilsartan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.37
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-86-BE39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.602343
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30665
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S0-EE-Y6WJ_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.417729
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13537
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3335
hsa-miR-587	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9169
FCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03469
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837104
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-7_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	1.0	null
picln	GeneRIF Biological Term Annotations	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.68154
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-68-YZ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227773
HIV-1_LAI_12Hour-UV_treatment_None_GSE56484	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.67124
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY 364947	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ribonucleoprotein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42725
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69399
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7854
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72304
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Charcot-Marie-Tooth disease type 2B2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
HA-38-ML65_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230232
spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.695148
AB-71-CI37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241519
EGFR_druginhibition_82_GSE27638	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.00122
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062876
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24015
GSE188814,GSE188854_0_v_1_wtap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of cell cycle process	GO Biological Process Annotations 2015	1.0	null
RMND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51445
4-Methylhistamine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.41
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068794
hsa-miR-219-1-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1274
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Y-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464068
U5 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.738
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35181
GK01981	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053127
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.29843
CC-50-FK24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208445
RNA Polymerase II Transcription	Reactome Pathways 2024	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.900069
SMAD3	ChEA Transcription Factor Targets	1.0	null
U1 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.532
STAT5A	ENCODE Transcription Factor Targets	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Iliopsoas muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S1-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10345
RNA cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
KC-26-JQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267251
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08948
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28017
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21895
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077251
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2085
GTEX-RM2N-0726-SM-48FD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940579
THAP11-20581084-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02458
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	1.0	0.981762
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08197
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.52784
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9608
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3627
DA-81-VY50_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406735
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05755
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6668
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25432
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3451-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.858389
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01696
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831791
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24023
SIRT6	ENCODE Transcription Factor Targets	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	1.77841
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AA-62-HP31_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37023
GSE180813,GSE180815_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.55791
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.905579
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.996
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01464
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.01517
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18058
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular	GeneRIF Biological Term Annotations	1.0	null
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0423
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258535
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1155_LUNG	CCLE Cell Line Proteomics	1.0	14.0966
hsa-miR-3160-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11702
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.1643
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979081
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935415
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.887418
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.963365
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.138
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.44427
496100373_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2664
POU5F1	ChEA Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36237
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18857
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063895
ott1_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.161732
9837_WDR70_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.507887
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850921
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.98611
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
AE-22-QI24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210809
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.26276
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
JE-04-LS32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26952
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39288
ESR1-17901129-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.38347
NB-17-SQ59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24955
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.84452
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JB-75-NC66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.737576
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.94747
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09439
positive regulation of G1/S transition of mitotic cell cycle	GO Biological Process Annotations 2023	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.85855
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962054
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03255
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-GeneID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5995
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04225
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26783
nucleoplasm part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BE-92-TW08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218142
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04668
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14558
replace	GeneRIF Biological Term Annotations	1.0	null
Cajal body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054131
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30234
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.637883
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37646
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09636
premrna	GeneRIF Biological Term Annotations	1.0	null
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sdma	GeneRIF Biological Term Annotations	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359467
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59142
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.7263
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.74693
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258593
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42633
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	3.13096
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14602
OLN-93 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
Yb body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.616
Cleavage body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66231
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.7192
SP2	ENCODE Transcription Factor Targets	1.0	null
GSK-LSD1	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WholeBlood	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0166
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06227
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881051
organic cyclic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
VA-06-DB75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36326
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AA-42-JP76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.47051
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2647
u7 snrnp	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.70273
superficial stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12174
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.6733
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916942
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39322
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.04586
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.18497
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of mitotic cell cycle	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-0926-SM-4AD4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06164
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29311
somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223662
PAX5	ENCODE Transcription Factor Targets	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4908
19139136-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.60996
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3492
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951276
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.70065
GTEX-P4QS-0226-SM-3NB1U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927979
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0864
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20596
DICER1_KO_GDS4504_585_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1777
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.908027
SYK_druginhibition_283_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.27663
GF-35-IT27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352674
EB2	CCLE Cell Line Gene Expression Profiles	1.0	1.4613
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19537
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02075
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARMCX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31807
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916739
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89186
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NE-24-ZO47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389634
Subgeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09152
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882292
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SALE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.60042
histone mRNA metabolic process	GO Biological Process Annotations 2025	1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826567
FLI1	ChEA Transcription Factor Targets	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21767
GSE190384,GSE190386_2_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.598248
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6ES-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.920304
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914624
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.45942
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49396
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836492
6863_PSMC6_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.4119
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.23466
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_11614_KD_C20orf18_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.30304
TAF7	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887881
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.47236
Cleavage of Growing Transcript in the Termination Region	Reactome Pathways 2014	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAUZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55845
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07699
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.98187
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06638
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55C-0526-SM-3GIKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918766
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13532
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49491
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04814
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.01603
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-y_TFEB_KO_LLOMe_VS_WTLLOMe_UP_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
NFPS	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
Prostate adenocarcinoma_PRAD_TCGA-M7-A723-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-04-AN21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282237
6870_PSMD2_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.85343
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00561
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZNF583	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11874
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3081
BATF	ENCODE Transcription Factor Targets	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03867
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.01371
Processing of Capped Intronless Pre-mRNA	Reactome Pathways 2024	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10108
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36929
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dinoprost	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.6
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871527
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86025
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12072
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.61219
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.84832
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16207
ribonucleoprotein complex	GO Cellular Component Annotations 2015	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455192
mRNA cleavage and polyadenylation specificity factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.208
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.92588
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70631
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.301604
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40507
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RA-49-ZB08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387246
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-9.58864
15656903-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CB-32-EI69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.322614
JD-62-HR05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.415037
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08448
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09959
Sarcoma_SARC_TCGA-SI-AA8B-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	2.30506
Integrator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13327
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2758-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1410_CDC73_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.51887
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8157_SMC3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.558461
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15328
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-30-TN36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266669
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.45966
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879574
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.876147
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2043
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.4771
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4345
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-69-DU95_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246566
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27471
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03999
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DC-23-UM36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.40228
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.38428
NRF1	ENCODE Transcription Factor Targets	1.0	null
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03491
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRAMD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01876
GTEX-XUZC-0326-SM-4BOO8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16053
AE-37-MC27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.358932
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.41099
ETS1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
SNRPD3	Pathway Commons Protein-Protein Interactions	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07445
Spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.861
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
factors	GeneRIF Biological Term Annotations	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863215
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291624
OE-84-HO42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.429982
Oligodendrocytic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
Tirofiban	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.27
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33398
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.134
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041291
CSF1R_druginhibition_195_GSE57686	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.65415
AE-88-WQ63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.607039
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.291365
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U7-06A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
u7 snrnp	GO Cellular Component Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45261
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31052
5339_MTOR_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.525533
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220096
17638893-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.04078
SW1116	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61286
BCP1	CCLE Cell Line Gene Expression Profiles	1.0	1.8421
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79049
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48453
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928652
AD-18-XC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276837
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.538362
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.36284
PRKACB_knockdown_91_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.13881
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3333
ACTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37485
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25461
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05744
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917889
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.28288
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98507
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842478
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
MI-3	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
BB-23-PM31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263072
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902496
SIN3A	ChEA Transcription Factor Targets	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6917500-elife-47110-supp1.xlsx-Table_I-Table_I_Differential_gene_expression_of_G0_G1-phase_invasion_cells_and_the_cells_treated_with_DMSO_SKI-73_and_SKI-73N_SKI	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
nucleoplasm part	GO Cellular Component Annotations 2015	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19042
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
types	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203-2004(H5N1)_2day-IDO1KO_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.66529
Perturb_11606_KD_ALOX5_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.09287
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.71043
GRPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08762
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
nuclear part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89141
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08018
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39191
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69899
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05836
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-96-HO33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.552299
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69855
E2F4	ENCODE Transcription Factor Targets	1.0	null
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC3230611-pone.0028509.s004.xls-Sheet1-Supplementary_Table_S2_The_list_of_273_differentially_expressed_genes_after_transfection_of_STAT6_specific_siRNA_in_NCI-H460_cells_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39971
UD-20-ER54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213057
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36818
transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.997386
9478_UBA1_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.528005
hsa-miR-3922-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941237
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49247
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35282
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.00227
Lung squamous cell carcinoma_LUSC_TCGA-58-8387-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23254
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43517
ZEB1	ENCODE Transcription Factor Targets	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3941
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.952847
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10877
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-82-CS38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239327
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43754
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neutrophil count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.53979
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0638
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27027
FD-20-OG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213839
Post-Elongation Processing of the Transcript	Reactome Pathways 2014	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.900258
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-0926-SM-4LVMJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910946
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8643
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-9.65246
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972838
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	1.37754
KP2	CCLE Cell Line Gene CNV Profiles	1.0	1.62818
ChIP_DMAP1_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.258432
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16753
4685_LSM10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-1.2711
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF4	ENCODE Transcription Factor Targets	1.0	null
U7 snRNP	GO Cellular Component Annotations 2025	1.0	null
H3K4me1_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Human - Tonsil - L2 - DZ-nonproliferative	HuBMAP Azimuth Cell Type Annotations	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317168
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of mitotic cell cycle phase transition	GO Biological Process Annotations 2015	1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23308
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918895
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.969268
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60155
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15283
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14287
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049732
icSARS-Cov_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.61351
PMC8120022-CTM2-11-e420-s006.xlsx-Sheet1-Table_S1_786_altered_genes_involved_in_cancer-related_pathway_in_TMPRSS2_ERG_fusion-positive_prostate_cancer_Genes_involed_in_multiple_pathways_are_duplicated_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63681
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08835
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8037
sno(s)RNA-containing ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.048
Fibrillar center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
EE-32-EY37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25239
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97062
dna-templated transcription, termination	GO Biological Process Annotations 2015	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laminin-6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73298
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26269
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.06792
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34908
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.03745
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.31689
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50186
RCOR1	ENCODE Transcription Factor Targets	1.0	null
SLBP independent Processing of Histone Pre-mRNAs	Reactome Pathways 2014	1.0	null
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.077
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.77788
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.95767
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14361
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.709545
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.84217
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.89668
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4944136-srep28995-s2.xls-ARGFX-gene_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of cell cycle	GO Biological Process Annotations 2015	1.0	null
ZBTB33_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6074
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4612
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OF-98-RK57_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214076
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843118
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84359
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3176	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46729
CDK5_knockdown_99_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.57924
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830367
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04484
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.840425
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00299
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12289
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.355
TEN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47889
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.19582
metabolic process	GO Biological Process Annotations 2015	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5789
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.622669
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.040615
ERG	ChEA Transcription Factor Targets	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65895
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.870039
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58295
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17185
ELK1	ENCODE Transcription Factor Targets	1.0	null
TCF3-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058538
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83246
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32314
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10656
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20397
4991_METTL14_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.596626
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33973
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LUF-5735	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15581
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53916
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3463
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3922-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD-16-KY17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361369
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
AD-09-MD49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406499
hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.309928
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13626
mRNA 3'-end processing by stem-loop binding and cleavage	GO Biological Process Annotations 2023	1.0	null
THAP11	ChEA Transcription Factor Targets	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
16715129-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98249
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5400-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC-71-BZ81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249398
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14811
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27917
CUX1	ENCODE Transcription Factor Targets	1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387404
intergeniculate leaflet	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14699
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.89821
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44084
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D2REFED4h_641_AR-D-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09807
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSANTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92802
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965243
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90433
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.92166
snrnp	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48853
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07022
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13477
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-7.43176
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Imaginal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
SNU1076	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50269
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25933
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05682
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.931517
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPAC	CCLE Cell Line Gene Expression Profiles	-1.0	-2.50063
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11473
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310773
RAD21	ENCODE Transcription Factor Targets	1.0	null
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47823
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45033
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55227
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14729
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32019
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52529
GSE199874_3_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40023
rna metabolic process	GO Biological Process Annotations 2015	1.0	null
17676974-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	-1.0	null
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
5748_NOP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.707643
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08279
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24671
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03252
HD-29-PZ41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373337
MTRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52145
U6atac snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.22
9482_UBA52_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.550248
SMN-Sm protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.362
NR2F2	ENCODE Transcription Factor Targets	1.0	null
aromatic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.927036
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874433
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04207
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13291
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.846758
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058906
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10127
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08268
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.41318
U7 snRNP	GO Cellular Component Annotations 2023	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE319_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	2.82288
small nuclear ribonucleoprotein complex	GO Cellular Component Annotations 2015	1.0	null
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475824
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.917434
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stem	GeneRIF Biological Term Annotations	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.975152
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892966
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34046
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232197
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868941
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.290295
Olodaterol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062596
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2616
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.909412
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40893
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11073
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919046
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42037
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IALM	CCLE Cell Line Gene CNV Profiles	1.0	1.50488
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.33348
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
Sarcoma_SARC_TCGA-DX-A8BK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09417
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828616
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.79121
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JD-58-MV19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256167
regulation of mitotic cell cycle	GO Biological Process Annotations 2015	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.22744
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7066
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34098
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45204
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871579
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eye	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23908
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45444
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleoplasm	GO Cellular Component Annotations 2015	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874433
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.16745
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A688-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874952
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8975
NCIH1341	CCLE Cell Line Gene CNV Profiles	1.0	1.84888
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.288
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845247
BC-13-OQ01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227188
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39757
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35655
snrnps	GeneRIF Biological Term Annotations	1.0	null
TRPM7_overexpression_305_GSE23102	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.96849
HCC1806	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71787
biological regulation	GO Biological Process Annotations 2015	1.0	null
GSE182680,GSE182683_5_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02262
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37028
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05228
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48539
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47985
KMRC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57774
HMGN3	ENCODE Transcription Factor Targets	1.0	null
AF-67-LZ82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.830303
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pICln-Sm protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.652
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08774
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863746
PRKCA_knockdown_118_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.8557
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88915
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21585
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.05759
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52092
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57904
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239436,GSE239441_0_v_1_keap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61293
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366333
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17446
DE-97-IV02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394977
morphine_mus musculus_gpl6246_gse17731	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-3B-A9HO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6362
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149264,GSE149267_2_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1818
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985093
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46091
859_BMS1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.570918
SNU719_STOMACH	CCLE Cell Line Proteomics	1.0	2.87151
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.196
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5881-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NE-00-JZ19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219983
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cell cycle process	GO Biological Process Annotations 2015	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.853898
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.870945
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_down_VENN-359_common_elements_in_HIF1_peaks_and_HIF1_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.40366
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39501
nuclear body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.813028
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.69577
NR1I2	ChEA Transcription Factor Targets	1.0	null
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36588
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.66743
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02709
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10087
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U2-type spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.59
7424_RPAP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.700458
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.697483
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30256
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79099
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972195
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11757
regulation of g1/s transition of mitotic cell cycle	GO Biological Process Annotations 2015	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.625993
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27798
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.25076
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
RSV_48Hour_22398282_GSE32138	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.86734
alpha6-beta4 integrin-laminin 5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.553
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.886841
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5144
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912796
small nuclear ribonucleoprotein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13278
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-12.9463
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04231
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26514
VA-48-RJ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26673
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19777
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
GSE210150_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GA-59-RW04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287513
GTEX-PLZ6-0526-SM-3P61C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64506
receiving	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.99057
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PSIP1_Deficiency_GDS2883_633_human_T-cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CerebellumPeduncles	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.948784
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-7.02365
h4s	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00199
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063327
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981569
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.7587
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25933
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055559
OSI-027	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.85
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.8166
H3K79me2_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
MERCK544	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03445
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31619
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95512
ERG-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-JV-A5VF-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KMRC1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
TCF3	ENCODE Transcription Factor Targets	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dg1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85967
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05751
EB-67-WB79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274775
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17096
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.852349
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56587
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04208
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
4685_LSM10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-1.0491
BANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03724
HA-22-CY42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346264
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3149
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.940226
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886563
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11585
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	Reactome Pathways 2024	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-77-MH38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418542
BB-64-EE60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383652
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74702
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8297
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.34996
RFX5	ENCODE Transcription Factor Targets	1.0	null
CA46	CCLE Cell Line Gene Expression Profiles	1.0	2.57806
ZBTB33_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8374
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	1.0	3.47995
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-92-TW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260868
LB-04-KP05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234518
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7091
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46089
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.03418
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23701
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
11227_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.50033
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19777
hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.216672
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864731
DB-24-CQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330694
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66326
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060176
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.26713
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03537
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isthmic part of the intermediate lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31919
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4531
HD-51-KD29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223413
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07257
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RNA Polymerase II Transcription	Reactome Pathways 2014	1.0	null
KB-92-MK13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.589253
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00877
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.98787
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01528
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1678
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69632
superficial stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09342
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15444
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27134
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965547
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76893
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50681
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28762
cellular process	GO Biological Process Annotations 2015	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
EML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.231
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K79me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997942
hsa-miR-488	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
Interchromatin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.839
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DB-18-UF01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262855
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05637
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5497
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-88-VW47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.510107
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49589
GSE231648_0_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26672
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-85-YK41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.335719
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44249
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5348
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6692-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56435
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	1.0	4.37273
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61416
Inflammatory bowel disease 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.544
PF-59-CY33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.768878
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.9494
USF1	ENCODE Transcription Factor Targets	1.0	null
U7 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.647
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69314
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0388
EF-75-JG46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300927
SIN3A-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCCIT	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
4149_INTS4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.500074
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25315
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66326
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.72348
SRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2501
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4167-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3566
ChIP_THAP11_20581084	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.917398
ELF1	ENCODE Transcription Factor Targets	1.0	null
Perturb_11610_KD_BPIL1_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.84582
SMN2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04475
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC11750912-12032_2025_2606_MOESM1_ESM.xlsx-AA_vs_AC-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Hypb_Deficiency_GDS3641_522_mouse_Yolk sac from E9 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02993
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PGBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23654
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060615
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.23642
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.02515
NCIH1693	CCLE Cell Line Gene Expression Profiles	1.0	1.36883
rbm15_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.161732
TE441T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.54185
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14976
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98601
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31856
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878439
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19661
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939206
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29371
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
P-body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
FAM47E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12133
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.19642
positive regulation of cell cycle g1/s phase transition	GO Biological Process Annotations 2015	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927509
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.842628
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.945536
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
AURKB_knockdown_92_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.6764
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926672
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.928487
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46278
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991529
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42696
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910272
THAP11-20581084-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08783
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17646
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rna 3'-end processing	GO Biological Process Annotations 2015	1.0	null
RAB33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29573
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4525	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GR-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12816669-41698_2025_1236_MOESM1_ESM.pdf-863-ZNF830_ZNF830	Rummagene Transcription Factor Associations 2026	1.0	null
PC-87-OG75_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242157
GTEX-XQ8I-1626-SM-4BOOI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863971
GSE190384,GSE190386_3_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.69063
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.59525
GTEX-XUZC-0526-SM-4BOPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02029
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SMAD2	ChEA Transcription Factor Targets	1.0	null
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41162
mRNA 3'-end processing	GO Biological Process Annotations 2025	1.0	null
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-94-AQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231552
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14581
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8798
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00082
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10008
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.17001
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.01081
AD-34-TG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340708
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15431
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DB-74-HJ91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303195
subcuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15537
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836946
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9247
7929_SIRT7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.528374
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.569622
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BA-95-YU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18724
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.982339
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NE-24-ZO47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257146
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50682
JA-23-QE71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207631
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACCMESO1	CCLE Cell Line Gene Expression Profiles	1.0	1.8199
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84495
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12698
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062091
SMAD2-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10604
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14302
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11756
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962119
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ac88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559301
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00072
organelle	GO Cellular Component Annotations 2015	1.0	null
smn	GeneRIF Biological Term Annotations	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.921059
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28018
GABPA	ENCODE Transcription Factor Targets	1.0	null
embryonic	GeneRIF Biological Term Annotations	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7862-01A-21R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8752
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21731
schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33965
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	1.50976
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36043
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23734
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06234
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
HCC1428	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52447
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.963571
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
HEK-293F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56655
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11226
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10861537-41467_2024_45595_MOESM1_ESM.pdf-108-TEAD2_target_genes_TEAD2	Rummagene Transcription Factor Associations 2026	1.0	null
AC-36-SY22_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390093
Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063792
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.30177
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22335
Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cajal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.821746
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15167
nuclear lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.434591
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01148
nuclear body	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BE-73-KD75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.522979
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21295
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4025
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Polytene chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.388
U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.439
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25523
CEBPB-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1448
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837097
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09544
TAF1	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72829
positive regulation of g1/s transition of mitotic cell cycle	GO Biological Process Annotations 2015	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.45023
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36308
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARS-CoV MA15_Day2_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.93416
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.29476
TYKNU	CCLE Cell Line Gene CNV Profiles	1.0	1.39122
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKT1_knockout_211_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.13194
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02842
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3_KO_Cnot6l_SRP152802	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.64849
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17034
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.09903
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90653
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.86804
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84052
HD-22-GO73_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392943
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.30577
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9150_KD_WTAP_SRP307037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.88654
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39613
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD-90-DS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256735
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5044-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04949
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.45637
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956598
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858121
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.830369
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.543723
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00487
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86192
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056249
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
NACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04481
GSE133683_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9743
POLR2A_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
JD-87-KA71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303028
AE-73-KX58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213746
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940527
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EO-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1122
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81256
TRIM24_knockout_298_GDS3087	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.96834
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2724
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.65657
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966234
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.80379
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5183
Endonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.065
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00462
Parabrachial nucleus, medial division, external medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46443
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.281085
HIR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867442
AE-51-ZO26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287536
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.100393
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16872506-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14558
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53473
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35857
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837551
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04003
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23808
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02744
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8288_SOX2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.615777
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4091
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09008
Colo-205 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
7455_RPL27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.825495
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40189
ZA-63-AC60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20833
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58078
AC-75-LR63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.408774
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0945
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.284253
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845572
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459973
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19076
contain	GeneRIF Biological Term Annotations	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERG-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE510_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	2.87151
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX5	ENCODE Transcription Factor Targets	1.0	null
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05687
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09932
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC13127299-mmc2.xlsx-FOXM1_kdRNAseq-hgnc_symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07535
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1692
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1603
FBXW11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35676
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	2.26182
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.44497
AB-18-YN11_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.34208
BF-22-EP86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17429
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
JC-02-ZR15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335594
hsa-miR-3173-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17096
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08212
LASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19048
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15576
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.081567
YA-34-DT48_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22647
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-66-OE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.664149
VD-76-SO91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239721
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-12.5144
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WF-96-ME07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282994
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15728
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05802
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88511
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLBP	Pathway Commons Protein-Protein Interactions	1.0	null
Nuclear body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.182
DF-93-BT88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399253
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.25581
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Metabolism of RNA	Reactome Pathways 2024	1.0	null
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SRF	ENCODE Transcription Factor Targets	1.0	null
MET_knockout_258_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.813373
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50585
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43199
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.04787
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AL-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.67408
positive regulation of mitotic cell cycle phase transition	GO Biological Process Annotations 2015	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DB-18-UF01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360729
9226_TRAF2_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.775912
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31753
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04916
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6L9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275128
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00824
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3222
AA-27-TF89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223107
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7036
MAFK	ENCODE Transcription Factor Targets	1.0	null
10803_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.574215
Lung adenocarcinoma_LUAD_TCGA-67-3772-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GB-69-YC71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214878
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1875
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36521
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AF-00-QK19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22914
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209109
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18326
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.685466
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.30922
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09308
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08271
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.743577
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66592
CC-09-YG11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212762
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEx Colon 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	7.45188
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0233
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514293
NANOG	ChEA Transcription Factor Targets	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897006
MA-58-RR04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319805
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.4076
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56919
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9333
JURLMK1	CCLE Cell Line Gene CNV Profiles	1.0	2.0555
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849617
ZNF143	ENCODE Transcription Factor Targets	1.0	null
ARL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03386
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.66743
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NA-29-UI75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220017
MC-51-BT07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201896
EVX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26605
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36184
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982916
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.966692
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.06435
Fetalbrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30568
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83T-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.703251
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36887
DAUDI	CCLE Cell Line Gene Expression Profiles	1.0	2.78498
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30526
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
kda	GeneRIF Biological Term Annotations	1.0	null
CHEMBL1597046	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00584
18535662-TableS2c	GeneSigDB Published Gene Signatures	1.0	null
DC-45-WU45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203639
SLC35F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03798
m2 part of pararubral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08835
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE178267_2_v_0_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37843
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.10542
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
BMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42013
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6806
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04556
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03255
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08692
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50925
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04847
GTEX-XUZC-1526-SM-4BRV4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890801
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17096
BECKER	CCLE Cell Line Gene Expression Profiles	1.0	1.41226
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ED-02-CL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440703
GSE171724_4_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31774
Koelliker-Fuse subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14492
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_TCF3_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913802
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.00777
embryonic lethality	MPO Gene-Phenotype Associations	1.0	null
10020_ZC3H13_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.791745
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20752
PMC4944136-srep28995-s2.xls-DUXA-gene_DUXA	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical layer of collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99504
10020_ZC3H13_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.64856
BL-41 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
Ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.377
5927_OGDH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.614213
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07277
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMAD3-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28792
Sarcoma_SARC_TCGA-DX-A8BS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.717888
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23963
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spliceosomal tri-snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59841
overexpression	GeneRIF Biological Term Annotations	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6909-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prenatal lethality	MPO Gene-Phenotype Associations	1.0	null
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.77173
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6436-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.296013
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912881
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46286
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	1.12761
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.823957
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2799
Adrenocortical carcinoma_ACC_TCGA-OR-A5KT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U7 snRNA binding	GO Molecular Function Annotations 2023	1.0	null
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SD-82-GT69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271258
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97325
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.97473
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6265
6793_PRPF31_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.515776
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.844484
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42687
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE189941_1_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03023
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5267
GSE169155_5_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KLHDC7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63323
histone mRNA metabolic process	GO Biological Process Annotations 2023	1.0	null
GSE249893_1_v_0_tfam_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
JC-63-DO70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.388101
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.55291
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834028
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26747
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27408
496100413_FWM_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3839
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37425
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27697
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
nuclear body	GO Cellular Component Annotations 2015	1.0	null
2893_TAFA2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.581675
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.74272
hsa-miR-3714	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	1.0	3.10987
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20156
PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
ILF3-29590119-K562-HUMAN-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19464
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.70442
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.36204
CD1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3738
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.81093
GTEX-OIZH-1526-SM-3NB1J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889166
BE-59-WG31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206787
ZFX-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5004_METTL3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.520155
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875441
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16347
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.853241
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22971
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20171
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.01081
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44832
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCAD_KO_GDS4546_422_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18993
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866651
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69099
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U2AF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23362
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58083
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1852
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06985
TD-40-ZR64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.342617
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.933008
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
Sm-like protein family complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06245
TAF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282401
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.960644
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94614
macroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062499
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
S2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.304
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058458
KC-26-JQ92_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341231
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7094
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21365
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cell cycle phase transition	GO Biological Process Annotations 2015	1.0	null
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6246
increases	GeneRIF Biological Term Annotations	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21655
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.28013
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K23ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08938
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893013
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.685948
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.31818
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2193
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7541_RPTOR_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.574325
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36243
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-VN-1203-2004(H5N1)_Day4-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.53759
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.06175
PMC12260418-pnas.2425984122.sd01.xlsx-TEAD4_6fraction_test_result-Unnamed_3_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932852
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1596
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0268
BF-49-KQ10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455485
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04771
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18044
ZNF736	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17457
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
normal	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleoplasm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.583431
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29173
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2728
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29159
Nuclear cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.925
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34908
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
trim28_23493425_cd71pluster119plus_sorted_from_bone_marrow_lof_mouse_gpl6887_gse44063	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.231774
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.598566
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857421
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825598
NRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94724
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76076
lateral orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.951427
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36944
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35653
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.89696
Arsenic	CTD Gene-Chemical Interactions	1.0	null
7091_RANBP10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.527712
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41586
Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4742856-srep20328-s7.xls-Sheet2-ZF_converted_to_Human_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.827669
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AKT1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50358
PMC11216188-peerj-12-17616-s013.pdf-8-ZBTB8A_ZBTB8A	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3877
OC-71-BZ81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329683
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12545
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1108
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
KC-36-DK23_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276466
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44325
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13255
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43458
FYCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65567
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB13-26457646-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
FOXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16088
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0865
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0844
nucleus	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08345
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-93-VT73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331292
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-66-2778-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887142
PB-09-OE00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.57618
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303809
AD-58-PW17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2465
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06332
CREB1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10863267-12864_2024_10083_MOESM2_ESM.pdf-8-HOXB1_HOXB1	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-CoV_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.11362
RD-92-QT24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217566
GA-77-MH38_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311719
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932723
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.512104
BHY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6599
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993009
BA-15-LA22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432332
YE-80-LN04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.420284
MXI1	ENCODE Transcription Factor Targets	1.0	null
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877595
U2 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.48
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
spinal trigeminal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.912152
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-91-JY05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213876
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35955
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.84141
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33716
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91038
GSE190384,GSE190386_2_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.09841
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957284
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11033
Omega speckle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.711
rna splicing	GO Biological Process Annotations 2015	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4454
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.99302
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25103
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02154
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-61-OO16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.824152
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53391
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21853
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
deferasirox_homo sapiens_gpl570_gds3558	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMN complex, U7 snRNA specific	CORUM Protein Complexes	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44835
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845818
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.415337
PMC12488502-41586_2025_9313_MOESM3_ESM.xlsx-ST-12-Supplementary_Table_12_PAX5_Interaction_Single_Genes_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.79012
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.03789
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63759
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095719
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233383
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Gene Expression	Reactome Pathways 2014	1.0	null
SB-94-ZA83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353147
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00199
Perturb_13278_KO_Mettl3_SRP254797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.35957
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PCM6	CCLE Cell Line Gene Expression Profiles	1.0	2.00394
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12689
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6846
A-CA-04-2009(H1N1)_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75891
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15859
lung fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.419623
Necrosis	CTD Gene-Disease Associations	1.0	1.61107
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999063
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.194045
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32494
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67467
CDK9_knockdown_71_GSE21751	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.866358
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20937
GSE255680_2_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059286
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04117
Labellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41342
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190384,GSE190386_3_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.12922
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.81617
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26994
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.58667
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055555
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0522
WSUDLCL2	CCLE Cell Line Gene Expression Profiles	1.0	1.52824
TGM2_KD_GSE23702_715_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299138
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-35-DU85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.16531
PMC6742760-41467_2019_12079_MOESM10_ESM.xlsx-Data_S8-Supplementary_Data_8_Target_genes_of_FOXA1-bound_enhancers_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3t6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.458
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63207
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18995
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10218
rna	GeneRIF Biological Term Annotations	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07235
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14889
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LYRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63581
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Post-Elongation Processing of Intronless pre-mRNA	Reactome Pathways 2014	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
d1like	GeneRIF Biological Term Annotations	1.0	null
GTEX-SE5C-1226-SM-4BRWV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857019
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.539
7163_RBM19_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.01876
MYC	ENCODE Transcription Factor Targets	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12534
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950625
GSE165548_2_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21273
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65603
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.73664
GA10	CCLE Cell Line Gene Expression Profiles	1.0	1.58331
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18701
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNA Polymerase II Transcription Termination	Reactome Pathways 2014	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
histone pre-mrna dcp binding	GO Molecular Function Annotations 2015	1.0	null
Lsm1-7-Pat1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.801
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6077
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.091041
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Thyroid nodule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
U4/U6 x U5 tri-snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984728
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63955
Compound eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47474
hsa-miR-16-5p	MiRTarBase microRNA Targets	1.0	null
MS (Multiple Sclerosis)_B Cell Lymphocyte_GSE10064	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.90451
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831609
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.555058
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851918
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914101
EE-02-BO83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21914
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2623
AE-11-VB80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305478
TCF3	ChEA Transcription Factor Targets	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.54875
GSE190384,GSE190386_6_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SB-94-ZA83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223975
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67782
JUND	ENCODE Transcription Factor Targets	1.0	null
ELF3-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1804
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MBTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16703
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41363
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1918
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BA-53-FM66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21156
ZFX	ChEA Transcription Factor Targets	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05975
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.733572
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31154
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.4087
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38613
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14086
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862318
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.7531
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00299
GSE210505_0_v_1_sox1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9242
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.35542
all	GWASdb SNP-Phenotype Associations	1.0	0.028286
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21741
ML349	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
NB-12-ZK38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211948
CTBP2	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
npatlsm10	GeneRIF Biological Term Annotations	1.0	null
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29311
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843524
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24464
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24336
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BA-84-TD72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.991397
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0396
GSE169155_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2432
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.93043
JD-87-KA71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241748
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.5796
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.823898
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.926951
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.40737
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6829
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78792
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5915
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82483
EF-52-ML96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265311
Mccoy	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22971
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
end	GeneRIF Biological Term Annotations	1.0	null
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6722
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.8365
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-11.9672
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4192
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55145
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48159
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839472
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.78512
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28464
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2835-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15718
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00199
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49447
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-9.6564
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
16618758-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78306
t47d	HPA Cell Line Gene Expression Profiles	-1.0	-1.03624
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.756
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848558
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H2-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01908
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21098
lsm11	GeneRIF Biological Term Annotations	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21587
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19661
U4 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
RNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90538
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18919
Gene expression (Transcription)	Reactome Pathways 2024	1.0	null
BB-79-AG41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233193
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56097
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.902853
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215209
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7036
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362223
organization	GeneRIF Biological Term Annotations	1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3562
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.18979
NIBR189	DeepCoverMOA Drug Mechanisms of Action	1.0	0.37
IGF1R_knockout_151_GSE32936	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.25256
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nuclear part	GO Cellular Component Annotations 2015	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17096
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30664
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.034
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12622
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24821
dexamethasone_mus musculus_gpl6105_gse44208	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24128
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47796
WI-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
TEAD4	ENCODE Transcription Factor Targets	1.0	null
transcription from rna polymerase ii promoter	GO Biological Process Annotations 2015	1.0	null
GTEX-P4PQ-0626-SM-3NMCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56126
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06913
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223473
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
ZBTB33_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44052
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34476
S0-EE-YNU4_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23297
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73544
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
modifications	GeneRIF Biological Term Annotations	1.0	null
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00594
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28887
PFEIFFER	CCLE Cell Line Gene Expression Profiles	1.0	2.19949
EA-93-KT88_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20867
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73884
Perturb_17663_KD_TRAF4_SRP292631	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
IU1	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01354
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47222
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03009
DC-23-UM36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1215
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02269
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412994
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62583
MTMR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11559
AB-80-CK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.714222
Heart Diseases	CTD Gene-Disease Associations	1.0	1.18126
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_hic_ZBTB12	Rummagene Transcription Factor Associations 2026	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50872
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68327
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85049
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242054
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.898625
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.43026
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830479
8218_SNRNP27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.531757
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40547
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973022
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6361
somatic	GeneRIF Biological Term Annotations	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.826494
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.917
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96763
GSE157557,GSE157559_1_v_0_parp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FB-33-LI31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35023
YC-45-JD42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.412914
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.212
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.971063
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36503
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875079
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SF3B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05274
nucleoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.555559
SOX2	ChEA Transcription Factor Targets	1.0	null
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15797
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
NLS-dependent protein nuclear import complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45565
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23769
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.12823
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.88679
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897006
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of cell cycle phase transition	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.77527
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU6_LUNG	CCLE Cell Line Proteomics	1.0	2.69529
PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_ZBTB12	Rummagene Transcription Factor Associations 2026	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
heterocycle biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881885
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00754
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17246
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4677
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24074
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.63682
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857855
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7747
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nuclear stress granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29311
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.55915
ED-91-LY45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305007
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_7day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.78586
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81333
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BB-93-VT73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264766
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.961387
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
PMC4521181-oncsis201520x8.pdf-205-MLXIPL_MLXIPL	Rummagene Transcription Factor Associations 2026	1.0	null
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96438
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.194
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36852
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00189
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.996042
Fetal_Intestine_Large	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.49925
mRNA cleavage stimulating factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.996
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83263
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842014
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESR1	ChEA Transcription Factor Targets	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905947
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.492
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47929
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2769
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85222
QA-07-KC40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216251
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947636
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.70721
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14156
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6796-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293982
HeLa-S3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.54427
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.07523
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964431
Sm-like protein family complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.89
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
pregeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1064
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01698
SMN-Gemin2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.178
outer CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24661
DOHH2	CCLE Cell Line Gene Expression Profiles	1.0	2.53385
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DD-54-MA35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.62077
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	1.36521
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13368
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30653
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00937
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7378
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.63744
Fatty Liver	CTD Gene-Disease Associations	1.0	1.25838
SNRPD2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAA50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40282
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
histone	GeneRIF Biological Term Annotations	1.0	null
DSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34063
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874433
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4501-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361799
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.84147
HS2ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52507
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38723
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835233
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897036
Sarcoma_SARC_TCGA-DX-AB2X-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.688892
BC-56-BB82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211427
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039181
complexes	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35501
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960836
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.49991
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15434
Cancer of Colon_Intestine - Large Intestine - Colon (MMHCC)_GSE4107	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.34322
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.52286
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.931543
Gemini of coiled bodies	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.142
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206176
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49238
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26C-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303984
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.14923
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.06641
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20947
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.73372
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23545
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892613
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.02
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78596
vivo	GeneRIF Biological Term Annotations	1.0	null
Blastoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.437
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.42995
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.508244
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07814
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221521
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21781
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35447
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052507
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39658
GSE108614,GSE108615_0_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169356_0_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr1_36397922_A_G_b38	GTEx eQTL 2025	1.0	1.35865
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adenoma_Colon_GSE4183	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.33197
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.25668
Medial geniculate complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2983
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24128
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKO	CCLE Cell Line Gene Expression Profiles	1.0	1.58159
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99129
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Pirenzepine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.67
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4032
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.57844
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
purified	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-QQ-A5V9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30091
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_248_KD_TPRX1/TPRX2/TPRXL_SRP361145	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.27582
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.70691
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20684
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.322
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34995
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.32532
PMC5263239-mmc2.xls-SEM_wt_MLL-Gene_name_1614_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7576
Medial geniculate complex, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48331
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2376_DROSHA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.618641
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45686
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43434
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34386
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074974
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138945,GSE138947_0_v_1_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_6_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72282
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41363
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52585
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.29471
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RD-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20387
oligodendrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236921
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.848812
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subnuclear	GeneRIF Biological Term Annotations	1.0	null
CC-47-VS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232281
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21587
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36136
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897006
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.65979
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78297
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1461
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO3	ChEA Transcription Factor Targets	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20694
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VC-19-YG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223412
MC-51-BT07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.386868
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308844
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981569
BECKER	CCLE Cell Line Gene CNV Profiles	1.0	1.63811
FURIN_Deficiency_GDS3512_568_mouse_T-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.28128
BF-26-MB27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355452
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flp-In-T-REx cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10296
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58037
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromosomal instability	MPO Gene-Phenotype Associations	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30967
Acute Myeloid Leukemia_LAML_TCGA-AB-2981-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33098
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27193
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.949608
PF-59-CY33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18034
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981212
SNRPD1	Pathway Commons Protein-Protein Interactions	1.0	null
RAPGEFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52986
RXRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26676
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04481
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.890235
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of mitotic cell cycle phase transition	GO Biological Process Annotations 2025	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26764
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
TE-15-RO34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.583721
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22698
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66918
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.20781
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53264
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.841636
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0029
POU5F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.833981
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	2.50043
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7036
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.3036
VCAP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2030_LUNG	CCLE Cell Line Proteomics	1.0	2.05154
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BBL003126	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
without	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4717-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.24349
DT-40 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
rna processing	GO Biological Process Annotations 2015	1.0	null
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89857
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior frontal gyrus, triangular part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.889007
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40523
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.729106
intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028306
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50143
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IH-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42193
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.27806
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.707152
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4756-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.97634
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
SMN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.363
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	126.2
VA-06-DB75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371744
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06898
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7979
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08795
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05456
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73415
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10495
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46267
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.84115
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26571
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01924
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940664
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68681
AE-88-WQ63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229458
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3405
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34019
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04728
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77717
mrna metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.867
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14302
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56649
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.83503
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.490644
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99916
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339723
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986093
QE-93-PG25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251814
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alpha-motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13119
Perturb_173_KD_Asns_SRP119931	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.5745
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.170114
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19584
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08695
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09415
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19159
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22439
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26127
GSE252988_0_v_1_lefamulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208761
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.1937
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.71109
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.365095
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898527
Cajal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.121
EP300	ENCODE Transcription Factor Targets	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin	HPA Tissue Gene Expression Profiles	-1.0	-1.15997
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83996
CHD2	ENCODE Transcription Factor Targets	1.0	null
HC-74-HM63_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.511617
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913767
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.13179
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	1.09889
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.954263
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.889252
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.952512
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18537
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2771-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1972_CWC22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.574277
COLO679	CCLE Cell Line Gene Expression Profiles	1.0	1.38906
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946527
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
TAF7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-1026-SM-48FDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21213
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58021
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75436
hsa-miR-3192	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
AF-83-BX08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.503814
GSE81193_0_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971947
AD-86-ES28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299944
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.04391
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.698799
snRNA binding	GO Molecular Function Annotations 2023	1.0	null
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04052
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31574
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
IMR32	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67949
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-92-HS43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.632008
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24128
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.048972
Perturb_6279_KO_TP53_SRP200689	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.91155
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61586
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C1orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24396
HMEL	CCLE Cell Line Gene Expression Profiles	-1.0	-3.34962
DC-51-WE27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229398
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3714
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01637
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824286
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
EA-62-MI89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257048
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A656-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1111
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13278
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914856
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	0.907036
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-87-SF89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.633321
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
rna binding	GO Molecular Function Annotations 2015	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.24959
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841952
muscle	GTEx Tissue Gene Expression Profiles	1.0	1.41261
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.40685
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.266
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35921
STK11_knockout_278_GSE34866	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.978896
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.857907
GSE123022,GSE123030_2_v_6_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.593471
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40963
SLBP independent Processing of Histone Pre-mRNAs	Reactome Pathways 2024	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45256
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5015
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856288
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.458759
SPI1	ChEA Transcription Factor Targets	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7	ChEA Transcription Factor Targets	1.0	null
S0-EE-Y79N_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245575
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.1238
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_18_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
WEE1_druginhibition_307_GSE38972	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.934409
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51863
MYBL2	ENCODE Transcription Factor Targets	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5267
GTEX-O5YT-1826-SM-32PK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41744
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.30662
POU2F2	ENCODE Transcription Factor Targets	1.0	null
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TA-19-YA45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211075
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904597
U7 snRNP	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smn complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.63715
Spironolactone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934532
GTEX-SE5C-1026-SM-4BRUG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994117
VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE	ChEA Transcription Factor Targets 2022	1.0	null
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.797911
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.937603
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839886
Perturb_14244_KO_IKZF1_SRP139731	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.64336
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992064
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.317685
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60716
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TU-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hela-s3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.833223
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06921
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20122
Sarcoma_SARC_TCGA-DX-A6BB-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Geniculate group, dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64075
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29364
Lung adenocarcinoma_LUAD_TCGA-38-4628-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56768
OB-17-DQ74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216168
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.48571
PMC7441006-41388_2020_1389_MOESM2_ESM.xlsx-Supplementary_Table_1-Prostate-Specific_MYC_Overexpression_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDK8_knockdown_88_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.61594
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AB-85-JR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23616
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.420942
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957925
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36308
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977204
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5004_METTL3_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.60919
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.13047
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881051
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02419
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385033
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118532_0_v_1_rnf168_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_7-Supplementary_Table_7_ETV6-repressed_genes_defined_by_dTAG_at_24_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.91966
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.6906
H1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26384
Perturb_11673_KD_SHFM3_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.43363
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270911
CCNI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14259
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23014
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.30758
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CDK8_knockdown_130_GSE30816	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.83354
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14386
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.878362
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.29081
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.713123
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0255
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.55506
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02781
PMC4494960-oncotarget-06-12587-s002.xlsx-LNCaP_MYC_Microarray-Table_S1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558347
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.729476
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIF1A_DEPLETION_GDS2760_642_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
U266B1	CCLE Cell Line Gene Expression Profiles	1.0	1.39593
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51N-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	Reactome Pathways 2014	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27628
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85148
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951723
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Barr body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84177
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11313
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31321
Adenoma	CTD Gene-Disease Associations	1.0	1.06771
FD-48-HZ39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.52348
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039903
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.07592
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58966
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20I-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.69867
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6175
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.84021
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17096
ESR1-17901129-mouse liver-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5055-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of G1/S transition of mitotic cell cycle	GO Biological Process Annotations 2025	1.0	null
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03055
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06245
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.50185
S0-EE-YEKU_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.351723
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910386
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RO-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27713
XEN445	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4105
GTEX-TML8-1526-SM-4DXUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81168
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.30861
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12787
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.990984
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
GTEX-XYKS-1026-SM-4BRVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949122
lack	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27064
SCHNEIDER-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.358
VDR	ChEA Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A815-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
6851_PSMB3_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.17072
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZB-93-OS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258212
Acute Myeloid Leukemia_LAML_TCGA-AB-2851-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5131
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Perturb_15646_KO_Tet2_SRP255385	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09237
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.701744
BMPR2	Pathway Commons Protein-Protein Interactions	1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664129
AD-09-MD49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318434
Acute Myeloid Leukemia_LAML_TCGA-AB-2856-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6534
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07796
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CD-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548an	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12035
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.854139
PRORP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02628
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OF-05-CB18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320228
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18294
CAF-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.052
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.39591
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5160_KO_Mettl3_SRP048598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.47071
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.878067
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67636
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46759
PMC8355885-gutjnl-2020-320652supp004.xlsx-RALY_KD_mRNA-seq-Table_3_RALY_Knockdown_in_HCT116_cells_mRNA-seq_log2_FC_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09932
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CI1	CCLE Cell Line Gene Expression Profiles	1.0	1.69343
JB-14-ZM03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.633667
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.836405
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938134
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00146
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981569
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02275
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0419
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871873
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8706
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.939267
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebrooculofacioskeletal syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.23587
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955555
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932502
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.613837
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059229
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845187
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14151
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.37236
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18658
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67756
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
histone pre-mRNA DCP binding	GO Molecular Function Annotations 2025	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2633
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24202
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50706
WB-54-WD35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224222
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20697
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96222
associate	GeneRIF Biological Term Annotations	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	0.93136
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-11.121
7389_RNF34_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.73007
Small nuclear ribonucleoprotein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25617
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.026357
GTEX-PWN1-1426-SM-48TDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841706
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04682
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2977
processing	GeneRIF Biological Term Annotations	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	1.01081
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52052
Perturb_14107_KO_Setd2_SRP220107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.41965
METTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91132
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37578
Viral cardiomyopathy_Myocardial tissue_GSE4172	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.40045
CRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00937
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
APOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05168
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5925
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.8546
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.84906
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20012
SDF2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20877
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906466
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940875
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.248578
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
NH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69136
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28514
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.698439
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00615
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967176
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881051
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04239
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051706
CE-03-YQ91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287881
PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NH6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63976
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30863
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.32664
Histone locus body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.576
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.692354
Small nuclear ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.882
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
selected	GeneRIF Biological Term Annotations	1.0	null
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44835
CA-42-YI34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268023
TC71	CCLE Cell Line Gene Expression Profiles	1.0	1.39815
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tauopathy	GWASdb SNP-Disease Associations	1.0	0.598248
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10218
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06014
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4954
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
PB-18-HD85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209751
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03887
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0822
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841823
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72832
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AA-49-BD04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205675
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.66383
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49245
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39065
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE62843,GSE64371_2_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160304,GSE163392_0_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_299_KD_TPRX1/TPRX2/TPRXL_SRP361145	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.9192
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ED-25-BD54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221672
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908067
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38378
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227178
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.976077
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859947
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2747
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	0.875831
Lung adenocarcinoma_LUAD_TCGA-44-3398-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29045
CB-46-FO63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250165
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
5470_NAT10_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.14459
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942123
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75902
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26403
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52377
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.89378
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of G1/S transition of mitotic cell cycle	GO Biological Process Annotations 2023	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84288
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09658
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26232
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18472
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22129
positive regulation of cell cycle G1/S phase transition	GO Biological Process Annotations 2023	1.0	null
TYKNU	CCLE Cell Line Gene Expression Profiles	1.0	1.85222
GSE200897_1_v_0_pold1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.68475
RNA Polymerase II Transcription Termination	Reactome Pathways 2024	1.0	null
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10859
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01015
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.13588
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063305
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POU5F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.73106
CASP4	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27724
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18521
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.452994
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00364
OACP4C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40507
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.645387
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056302
RUNX1	ChEA Transcription Factor Targets	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13675
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AV-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XD-40-HA98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384227
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.544
9454_TXNIP_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.54899
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09439
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07275
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.970331
cell part	GO Cellular Component Annotations 2015	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06034
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-7.34475
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nuclear lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CC-08-JZ09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277404
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17244
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.4564
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41641
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12539
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07649
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.888142
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190384,GSE190386_0_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38728
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.61918
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3826
4991_METTL14_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.734692
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.49032
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF473	Pathway Commons Protein-Protein Interactions	1.0	null
salivary gland	HPA Tissue Protein Expression Profiles	1.0	1.01081
ML218	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.979992
WC-09-GD62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287752
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CITED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03469
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1184
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166191
Cytoplasmic U snRNP body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.088
histone locus body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.36417
YB-58-IZ37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208537
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3979
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.3688
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.82502
DB-18-UF01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.404027
ChIP_POU5F1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11164
hepatitis c	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.518034
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STRAP	Pathway Commons Protein-Protein Interactions	1.0	null
KA-72-WY22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280967
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978461
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944271
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28861
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56367
BE-38-UW72_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221061
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66812
NUDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88807
Anastrozole	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01591
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29777
DA-81-VY50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348108
Ommatidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02781
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.10132
Prostate adenocarcinoma_PRAD_TCGA-EJ-7318-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77J-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Annuli extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4609
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080804
dementia	GWASdb SNP-Disease Associations	1.0	0.352142
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897006
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843736
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59509
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.579796
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.707601
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U7 snRNA binding	GO Molecular Function Annotations 2025	1.0	null
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277867
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92887
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06972
FOXA1	ENCODE Transcription Factor Targets	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLNS1A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38083
compromised	GeneRIF Biological Term Annotations	1.0	null
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88475
NLRP1 inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57104
LSM3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38484
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05329
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rifampicin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
Geniculate group, ventral thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01191
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23161
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05878
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Linagliptin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
DC-84-CJ21_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.550414
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08866
4805_MAP2K7_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.08556
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.433
HEC265	CCLE Cell Line Gene CNV Profiles	1.0	1.63564
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953724
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22444
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64331
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25598
CREB1	ENCODE Transcription Factor Targets	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7857
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47603
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.67722
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.27782
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-80-GK24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260927
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14102
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61037
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
mrna 3'-end processing	GO Biological Process Annotations 2015	1.0	null
RCM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45903
UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.97343
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24909
ZNF384	ENCODE Transcription Factor Targets	1.0	null
MB-15-ZF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.654888
RWDD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23366
GSE140074_1_v_0_kif20a_human	RummaGEO Gene Perturbation Signatures	1.0	null
snRNA binding	GO Molecular Function Annotations 2025	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.27502
CA-68-TC79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363683
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2307
Nurse cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.583
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137144_3_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07833
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.53568
CF-48-QD87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373251
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-124-3p	MiRTarBase microRNA Targets	1.0	null
SMAD3-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CB-02-XL81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.335071
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.609
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06263
organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.364713
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.170114
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.625429
U4/U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.098
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.22479
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42738
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30263
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26147
GSE143462_0_v_1_omipalisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914801
PF-59-CY33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.465489
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01604
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48424
liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.214297
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UBB_KO_GDS3906_492_mouse_Testis -  14 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144796_1_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.06588
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-5337-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03954
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05054
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05713
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23628
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the lateral lemniscus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05174
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21681
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75I-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
10062_ZEB2_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.53611
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56275
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20697
hsa-miR-24	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KAT2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999765
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03935
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.76765
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44891
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040361
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6857_PSMC1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.15289
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18095
7585_RTF1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.504248
HIF1A_01_86	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.21882
PML	ENCODE Transcription Factor Targets	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93967
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943524
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041795
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39388
mrna processing	GO Biological Process Annotations 2015	1.0	null
GSE133683_1_v_5_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920166
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824281
CD-16-KY17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25276
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22748
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CACO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44107
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00576
Ribonucleoprotein LSM domain	InterPro Predicted Protein Domain Annotations	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14544
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.15753
CHP126	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86192
DB-33-TM61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354152
GTEX-XBED-2426-SM-4AT4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1655
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65308
BF-02-AC35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360456
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-8.99059
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49843
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982258
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323599
GD-82-CS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238814
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825903
6032_PAF1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.663226
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56994
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945991
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CC-50-FK24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25026
EC-82-LV30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.370166
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
effect	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.393348
SNU1079	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54329
CORL24	CCLE Cell Line Gene CNV Profiles	1.0	1.49041
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BE-27-XF09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298328
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193177_1_v_2_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56394
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837551
PMC7423359-abb8771_Table_S4.xlsx-Sheet1-Genes_detected_at_least_twice_in_h4E_BP1-hyperTRIBE_711_genes_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46002
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48834
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850669
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.254743
Perturb_301_KD_TPRXL_SRP361145	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.26664
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.54428
Germarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
SYK_druginhibition_286_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.00702
KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YA-85-VH07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264578
ETS1	ChEA Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27221
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2228
GTEX-TKQ1-0326-SM-4DXSM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34701
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05816
TCF3-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE80537_5_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6626
GTEX-PWOO-0626-SM-48TZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854355
VMCUB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91388
CIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06482
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CB-32-EI69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204959
6867_PSMD13_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.35791
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.134
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877546
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.41221
hsa-miR-4663	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830087
MD-92-LN15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228865
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9568
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.930189
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09678
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Odanacatib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.49
Ventilator-associated lung injury_Lung Tissue_GSE2411	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.30802
496100499_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23804
Inflammation	CTD Gene-Disease Associations	1.0	1.56068
TFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13641
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00199
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17363
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22237
NFYA	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35402
Inflammatory bowel disease 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01881
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
8594_SUPT16H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.500388
A 438079	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
GB-35-DG61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301276
GTEX-QV44-1026-SM-447CG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826029
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47044
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876562
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33312
Perturb_8008_OE_TP53_SRP406950	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.98927
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36937
Lsm2-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.417
cajal body	GO Cellular Component Annotations 2015	1.0	null
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ADRA2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04045
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4753-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.956574
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RASSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04097
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73526
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236627
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBP2_deficiency_GDS2731_62_mouse_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HA-32-YH61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283461
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05664
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51966
hsa-miR-3616-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Sumatriptan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
FOXO1_KD_GDS2720_477_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.960961
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A6SH-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12711
hsa-miR-1291	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.83
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
6872_PSMD4_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.16134
Learning Disorders	CTD Gene-Disease Associations	1.0	1.29348
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.90901
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43287
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.865917
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.809975
GA-87-BR97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35103
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15317
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.29911
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56524
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54481
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4595
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.382957
Second instar larva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1365
Histone pre-mRNA 3'end processing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.751
GTEX-XQ3S-1026-SM-4BOPJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891051
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7613
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930423
STAT1	ENCODE Transcription Factor Targets	1.0	null
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.168985
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.260202
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2236_DLAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.554158
EA-84-SC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219747
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85611
GSE198165,GSE198166_6_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12486367-Supplementary_Data2.pdf-407-ZNF792_ZNF792	Rummagene Transcription Factor Associations 2026	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24128
YE-55-YX75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.452314
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895347
EWS502	CCLE Cell Line Gene Expression Profiles	1.0	1.54973
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00061
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10532
Perinucleolar compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43722
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842441
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69074
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.53272
u7 snrnp	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.37147
MRPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56026
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870956
SNRPB	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.824958
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Processing of Capped Intronless Pre-mRNA	Reactome Pathways 2014	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88R-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.27138
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2062
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960437
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63707
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961597
AD-86-OB87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.378929
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HF-79-EC41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243715
TAL1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.10081
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB-20-LP90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383477
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72829
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04681
positive regulation of cell cycle	GO Biological Process Annotations 2015	1.0	null
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28709
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2455
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40067
SP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1675
MSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02476
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865275
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44927
histone pre-mRNA DCP binding	GO Molecular Function Annotations 2023	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6499
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24405
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.931868
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43564
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43Y-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.787359
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29774
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3818
EF-01-LB20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213845
Metyrapone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.97
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01703
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.01081
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01353
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.74608
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592043
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AD-86-OB87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252619
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53052
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31186
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.40477
CE-95-YX02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.437762
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061557
Medial geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60086
Ovariole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LSM11	Pathway Commons Protein-Protein Interactions	1.0	null
RNA binding	GO Molecular Function Annotations 2023	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Epristeride	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spliceosomal snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.517
CF-42-OS28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.449154
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00977
6071_PARK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.871709
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-7.58045
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32667
disease	GWASdb SNP-Disease Associations	1.0	0.024048
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15328
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50706
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.094
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BC-15-EL49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.814582
AA-46-GL76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317922
HA-22-CY42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298393
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU-387 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01502
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34544
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13799
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.63617
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.43185
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6644
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65859
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04936
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74856
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85999
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11757
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22056
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KPNYN	CCLE Cell Line Gene Expression Profiles	-1.0	-2.36297
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3201
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57102
FOSL2	ENCODE Transcription Factor Targets	1.0	null
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.134
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 6a of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26174
small nuclear ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.44968
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09078
histone mrna metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE167004_0_v_3_thpo_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
nucleobase-containing compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01345
THAP1	ENCODE Transcription Factor Targets	1.0	null
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33479
HEP3B217	CCLE Cell Line Gene Expression Profiles	-1.0	-2.32264
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.998827
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	1.0	4.13773
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832552
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.1385
prmt5	GeneRIF Biological Term Annotations	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15446
TF-04-RX73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327749
gyrus rectus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842135
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93295
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.460808
superficial stratum of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00391
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00299
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863357
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4887
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.830221
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2732
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.01081
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070177
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30128
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0667
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.99497
H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91641
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27725
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.84187
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.24887
DF-00-BU08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264486
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43359
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Oogenesis phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
AA-52-JS03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203436
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01417
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210569
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920706
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00623
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845961
oligodendroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219047
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36402
motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.575616
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18413
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
UD-07-US73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207323
Lung squamous cell carcinoma_LUSC_TCGA-46-3765-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_10_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2444
LE-80-BM08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214064
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58713
143B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3618
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.472969
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hybridoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.272
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vitro	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25994
GA-30-HJ41_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227853
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99734
Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DP-agonist13	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0939
FC-61-BK21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272912
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nuclear body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Salmeterol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.61
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835011
DA-35-DU85_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244553
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49926
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.74582
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.02613
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1917
BE-90-YK54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374414
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.847662
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08555
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98741
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39641
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.856889
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14318
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07811
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932603
GSE111247_2_v_9_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29074
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96797
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.1931
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37717
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.94561
hsa-miR-4716-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MRPS18C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18145
ribonucleoprotein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Lung adenocarcinoma_LUAD_TCGA-50-5045-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980357
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23604
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.70801
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850507
OB-15-UL37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.389175
BATF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital adrenal insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
SREBP1-19666523-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120336_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.42218
AA-39-BD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2971
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47743
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31951
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56116
SCC9	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48949
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-10-GX45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.382043
CD-26-MB82_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220286
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.57234
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.47195
GTF2B	ENCODE Transcription Factor Targets	1.0	null
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.01081
Glaucoma_Retina_GSE3554	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.69263
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40896
Muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18768
STIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97579
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04203
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13169
AA-46-GL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236793
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.149316
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39935
Anterior olfactory nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31185
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Lung adenocarcinoma_LUAD_TCGA-49-4507-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2661-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH526	CCLE Cell Line Gene CNV Profiles	1.0	1.74326
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30928
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882763
skmel30	HPA Cell Line Gene Expression Profiles	1.0	1.25343
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040889
nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36395
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14481
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04198
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.184367
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04521
8433_SRSF3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.543607
TE-67-XP56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209482
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866248
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834028
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29321
CA-48-JF51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252541
Like-Sm (LSM) domain	InterPro Predicted Protein Domain Annotations	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28211
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89773
SIX5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.32458
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5333
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-10.547
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13139
CB-82-PL01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.844486
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877196
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13129
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10786
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.926052
Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNU-120596	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
GATA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961801
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.54268
C2BBE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71237
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.36284
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079261
SIN3B	ChEA Transcription Factor Targets	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.280716
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
DMB	DeepCoverMOA Drug Mechanisms of Action	1.0	0.43
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.947395
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66762
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5880-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.60268
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32293
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.01081
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.45038
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05351
R121919	DeepCoverMOA Drug Mechanisms of Action	1.0	0.45
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_8-Supplementary_Table_8_ETV6-repressed_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994758
KAT2B	ENCODE Transcription Factor Targets	1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.00097
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940875
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40771
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83946
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91571
ID-90-NM43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216786
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22707
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.928291
Diverticulitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02117
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21453
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897006
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.823957
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56208
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937471
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45061
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347778
GSE205788_0_v_1_gfap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977057
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-71-CI37_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215092
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-95-YU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275275
coelom	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.460692
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF	ChEA Transcription Factor Targets	1.0	null
KA-62-FE69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239134
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940875
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45209
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cellular nitrogen compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.10152
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96212
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0485
KLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54664
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Transcription	Reactome Pathways 2014	1.0	null
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312494
Paraspeckles	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040204
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48575
DB-56-XL71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.650138
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.996884
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38151
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9574
positive regulation of mitotic cell cycle phase transition	GO Biological Process Annotations 2023	1.0	null
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27904
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46099
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.2174
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.01081
Lung adenocarcinoma_LUAD_TCGA-64-5778-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.984518
abnormal chromosome stability	MPO Gene-Phenotype Associations	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63303
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23873
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0854
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SB-94-ZA83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.722233
gene expression	GO Biological Process Annotations 2015	1.0	null
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287672
PANC0213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71616
NCIH2122_LUNG	CCLE Cell Line Proteomics	1.0	8.02079
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81677
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4289
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06662
GSE179002_0_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1943_CTR9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.551912
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5579
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA 3'-end processing by stem-loop binding and cleavage	GO Biological Process Annotations 2025	1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869002
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6814-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.87134
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32861
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43641
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20303
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984292
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
9396_TTF1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.534586
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29816
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998933
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839908
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274461
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.672054
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.91248
TET1	ChEA Transcription Factor Targets	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19059
MCF7_Mocetinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0087385
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.529273
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.43129
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24089
Lung adenocarcinoma_LUAD_TCGA-38-4632-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393992
AMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3716
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.04716
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.878886
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13255
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07296
AA-62-HP31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.643884
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57467
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8208823-mmc2.xlsx-CDX2-KO_mesenchymal_DEG-feature_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28104
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56452
IRAK1_knockdown_115_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.71507
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42632
eGFP-NR4A1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2578
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17252
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29808
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24949
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-51-CQ55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271288
BC-13-OQ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.627559
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880095
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.933957
17699763-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22971
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9913
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86268
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01243
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-8.88465
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903276
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
4651_LRP8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.699517
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16541
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.464058
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35778
hacat	HPA Cell Line Gene Expression Profiles	-1.0	-0.89218
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.09557
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.47075
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.616746
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14558
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14106
C11orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01718
SNU899	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16475
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058943
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27863
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27119
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859721
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.565843
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.22487
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24735
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.79896
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5087
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5236
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93415
regulation of cell cycle g1/s phase transition	GO Biological Process Annotations 2015	1.0	null
RA-42-CM42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321447
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40023
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31021
positive regulation of G1/S transition of mitotic cell cycle	GO Biological Process Annotations 2025	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34315
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50441
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066597
Methylosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.635
Perturb_1666_KO_Rigi_SRP119759	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.36631
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58174
Cytoplasmic U snRNP body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00199
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826377
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7167
U12-type spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.34
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.09527
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96843
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063558
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08131
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.99078
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-4_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lsm10	GeneRIF Biological Term Annotations	1.0	null
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.0184
SMAD2-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45187
termination of rna polymerase ii transcription	GO Biological Process Annotations 2015	1.0	null
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19491
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14558
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56032
regulatory	GeneRIF Biological Term Annotations	1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-5_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
cajal body	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.55494
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90395
GTEX-S7PM-0426-SM-3NM91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918796
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67949
AD-11-RL84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.314692
Poisoning	CTD Gene-Disease Associations	1.0	1.59661
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04916
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01353
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879903
daudi	HPA Cell Line Gene Expression Profiles	1.0	1.33559
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13678
KDM5B	ENCODE Transcription Factor Targets	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66413
KB-49-NF63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219755
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02376
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.934013
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0557
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25479
DC-23-UM36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331414
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8429
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kc cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
L428_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.24615
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30948
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876599
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.067185
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.5173
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530873
SA-32-CC58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378006
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.42992
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.898875