association	dataset	threshold value	standardized value
Extracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.438
GSE131649_6_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5366
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6702
SBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80218
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89375
vascular disease	GWASdb SNP-Disease Associations	1.0	0.165544
GSE145682_1_v_0_nbdy_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7869
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.713
reverse-transcriptase-polymerase-chain-reaction	Phosphosite Textmining Biological Term Annotations	1.0	null
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	1.5069
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.295
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1122
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
GFI1B	ChEA Transcription Factor Targets	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
l35	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57206
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139455_2_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Membrane attack complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.059
YAP_OE_GDS3220_32_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23301
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FER	Kinase Library Tyrosine Kinome Atlas	1.0	99.85
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53299
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.63887
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.568823
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2995
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.57941
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.0757
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0035
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29C-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9161
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.017
EPHA3	Kinase Library Tyrosine Kinome Atlas	1.0	99.06
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A23Z-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.889
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87001
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897677
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2426
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0156
obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5246
connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.212421
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0086
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-intersection_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.89565
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4143
ADH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20343
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.495833
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7673
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40025
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9547
NCIH520	CCLE Cell Line Gene Expression Profiles	-1.0	-2.71935
BL-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05763
Frontotemporal Lobar Degeneration	DisGeNET Gene-Disease Associations	1.0	null
SCH	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7101
HEC-1-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZP-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.929592
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acetylcholine receptor inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9813
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57806
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62462
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939138
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1627
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2784
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.4947
Pyrenoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
Acute Myeloid Leukemia_LAML_TCGA-AB-2865-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L1236	CCLE Cell Line Gene CNV Profiles	1.0	1.42512
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148692,GSE148695_2_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11541
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3699
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6906-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855994
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7413
rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.78282
CH157MN	CCLE Cell Line Gene Expression Profiles	1.0	1.35914
artery disease	GWASdb SNP-Disease Associations	1.0	0.218546
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856234
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0171
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4078
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5529
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24261
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2487
FLI1	ChEA Transcription Factor Targets	1.0	null
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5173
Iminoglycinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TNFRSF10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8212
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.256351
GATA2_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8054
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1125
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1087
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2573
vagina	HPA Tissue Protein Expression Profiles	1.0	1.30612
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-5398-01A-02R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHSY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47385
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.082561
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.228333
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.432
glucose metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.69843
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2524
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7321
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18639
Uterine cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827122
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27012
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.19822
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4514
SNU1077	CCLE Cell Line Gene CNV Profiles	1.0	1.40158
GATA1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.414
H3K4me1_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bp94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060799
pre-B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
Tracheal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5106
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bursa copulatrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.35364
pervanadate	Phosphosite Textmining Biological Term Annotations	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	2.3754
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone disease	GWASdb SNP-Disease Associations	1.0	0.451794
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6652
Uterine lavage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.6705
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-2.18331
Perturb_12554_Mut_Atxn1_SRP148491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.76473
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.414
STARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11811
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9574
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9954
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01853
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4198
PMC4445818-13062_2015_58_MOESM2_ESM.xlsx-NSCL_Adjacency_Lists-Gene_symmbol_for_Protein_B_NHLH1	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-3R-A8YX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8206
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050816
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.5684
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7949
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34497
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30022
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GRB7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Secretory granule membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Sarcoma_SARC_TCGA-FX-A3NK-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Degeneration of macula and posterior pole	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_1_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7304
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65656
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5655
Blood platelet	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Omasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.1781
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_467_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.978
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891255
disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.69843
Lung non-small cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.527
EPHB2	Kinase Library Tyrosine Kinome Atlas	1.0	98.62
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5682
EPHA8	Kinase Library Tyrosine Kinome Atlas	1.0	97.61
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56885
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.318
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82939
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94109
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5984
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.829
ultrastructure	Phosphosite Textmining Biological Term Annotations	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4926
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2533
basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.513802
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7236
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
HEL	CCLE Cell Line Gene Expression Profiles	1.0	3.01219
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.318
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3542
Nde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8111
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2174
Peritoneal exudate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05864
JJN3	CCLE Cell Line Gene Expression Profiles	1.0	1.48157
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dose-response-relationship-drug	Phosphosite Textmining Biological Term Annotations	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4474
LHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84531
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.449
FES	Kinase Library Tyrosine Kinome Atlas	1.0	99.72
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.498
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4795
Head kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.3
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.236
age-related macular degeneration	GWASdb SNP-Phenotype Associations	1.0	1.01377
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3767
Autism spectrum disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.311
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WL-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Early endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.717
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.96313
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MEIS1	ChEA Transcription Factor Targets	1.0	null
BRCA1_DEPLETION_GDS3791_38_human_Hela	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1871
ZNF460	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81345
Leprosy	HuGE Navigator Gene-Phenotype Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
platelet alpha granule	GO Cellular Component Annotations 2023	1.0	null
UT7	CCLE Cell Line Gene Expression Profiles	1.0	2.27374
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.069196
phosphotyrosine	Phosphosite Textmining Biological Term Annotations	1.0	null
SNU475	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53492
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29342
CSK	Kinase Library Tyrosine Kinome Atlas	1.0	96.43
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immunoglobulin-like fold	InterPro Predicted Protein Domain Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2859-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervix disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4979
BLK	Kinase Library Tyrosine Kinome Atlas	1.0	95.91
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47536
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.79
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1545
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.34604
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	1.4073
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6823
tyrosine-phosphorylated	Phosphosite Textmining Biological Term Annotations	1.0	null
mRNA_TCEA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ANKRD65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91072
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38128
Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H4-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.58036
Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_12_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6772
RUNX1	ChEA Transcription Factor Targets	1.0	null
EPHB1	Kinase Library Tyrosine Kinome Atlas	1.0	98.67
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Immunoglobulin subtype	InterPro Predicted Protein Domain Annotations	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47536
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.5021
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084715
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.728
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3919
platelets	Phosphosite Textmining Biological Term Annotations	1.0	null
LN215	CCLE Cell Line Gene Expression Profiles	1.0	1.46598
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WT-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Renal glomerular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28016
SRSF9_02_134	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.77761
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08761
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886859
lupus erythematosus, systemic	GAD Gene-Disease Associations	1.0	null
Macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	1.72905
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17085
breast	HPA Tissue Protein Expression Profiles	-1.0	-1.08116
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
blast cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9767
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU478	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98037
GSE144481,GSE144483_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COL18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27437
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8489
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50877
Hemostasis	Reactome Pathways 2024	1.0	null
Nephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.017
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961483
platelet alpha granule	GO Cellular Component Annotations 2025	1.0	null
lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
ZNF384	ENCODE Transcription Factor Targets	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53624
U343	CCLE Cell Line Gene Expression Profiles	1.0	1.7295
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.65067
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A719-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
SLR21	CCLE Cell Line Gene Expression Profiles	1.0	1.68065
MYC_OE_GDS4763_332_human_MCF10A - immortalized breast epithelial cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61207
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3229
UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.402813
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3064
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8582
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.59842
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31076
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cortisone reductase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A1-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A6BG-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59858
Hypnozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.768
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
VAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70224
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978496
JK1	CCLE Cell Line Gene Expression Profiles	1.0	1.80937
EPHA2	Kinase Library Tyrosine Kinome Atlas	1.0	97.48
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941162
USF2	ENCODE Transcription Factor Targets	1.0	null
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4018
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49407
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
signal	Phosphosite Textmining Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A1NK-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.155839
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6689
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0597
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.548
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2418
outer SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935273
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12264
secretory granule membrane	GO Cellular Component Annotations 2025	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63019
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33736
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9167
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.823
respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4533
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4162
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6427
colo741	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02284
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043099
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.14191
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824526
PMC11637729-BJH-205-2450-s001.docx-0-GATA2_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH446	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60275
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6XA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
143B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6015
Pervasive developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.311
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	101.288
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	1.79489
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	2.46159
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.30612
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Takayasu's arteritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.696
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6668
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47335
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.017
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.91
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
Immunoglobulin-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SRC	Kinase Library Tyrosine Kinome Atlas	1.0	95.75
bone marrow cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9635
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7611
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1045
SOX2-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3517
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.792
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5604
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EM2	CCLE Cell Line Gene CNV Profiles	1.0	2.0095
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4636-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Human - Fetal Development - L2 - Cerebrum-Megakaryocytes	HuBMAP Azimuth Cell Type Annotations	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94343
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1298
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2805
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.2758
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0578
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ChEA Transcription Factor Targets	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.713
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7949
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24766
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-IW-A3M4-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA1_G1E-ER4_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Asthma (childhood onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0247
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
adaptor	GeneRIF Biological Term Annotations	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3248
macular degeneration	GWASdb SNP-Disease Associations	1.0	1.16047
glutathione-transferase	Phosphosite Textmining Biological Term Annotations	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.30612
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09983
IZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.872416
chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.189
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36324
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851325
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1259
protein-processing-post-translational	Phosphosite Textmining Biological Term Annotations	1.0	null
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48739
RCOR1	ENCODE Transcription Factor Targets	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4112
ARID4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81512
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9611
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-0.898226
GSE145476_2_v_3_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3248
MHC protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.068
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47795
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.2646
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.702
SOX7_01_299	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.67616
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SETD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57249
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7226
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
megakaryocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5859
Cervical cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54483
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.670866
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897677
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.11612
Response to elevated platelet cytosolic Ca2+	Reactome Pathways 2024	1.0	null
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2771
t30-blood-rna_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	5.72005
type 1 diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.69843
grb7	GeneRIF Biological Term Annotations	1.0	null
MEC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33072
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13069
Perturb_14229_KO_Kdm2b_SRP060647	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.2921
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.80497
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.1714
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858465
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86378
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0571
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
MPT synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050713
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.75697
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ester	Phosphosite Textmining Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.0517
IGFBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82788
GSE135334,GSE136010_2_v_3_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7162-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2679
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
Female reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.11818
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.829
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3488
disease	GWASdb SNP-Disease Associations	1.0	0.078322
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856619
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.2666
GSE176008_4_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.7291
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.30612
PMC6366099-13075_2019_1825_MOESM8_ESM.xls-LPS-regulated-sites_txt-Gene_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
clonem3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883331
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.648
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.10589
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.888
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897677
Rectum adenocarcinoma_READ_TCGA-F5-6864-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6747
HT55	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35466
Blood microparticle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.297
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9816
adult stem cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8925
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55306
CALML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66297
Tertiary granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.619
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.2006
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85166
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72024
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4096
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.973239
abnormality of the retina	GWASdb SNP-Phenotype Associations	1.0	0.261844
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937684
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SNU503	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60482
DUX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5201
znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.584527
GATA1_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ulcerative colitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.4301
Specific granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
cross-linking	Phosphosite Textmining Biological Term Annotations	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0738
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.35364
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphocyte antigen 6 complex locus protein G6d/G6f	InterPro Predicted Protein Domain Annotations	1.0	null
thrombin	Phosphosite Textmining Biological Term Annotations	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973404
Platelet activation, signaling and aggregation	Reactome Pathways 2024	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.875
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.9583
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
496100387_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46134
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MTSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98305
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981551
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A817-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
LMO2	ChEA Transcription Factor Targets	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1518
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3218
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.158382
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0529
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83912
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0819
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4254
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3235
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brush cell (Tuft cell)_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0543
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Uterine disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89539
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9948
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050816
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4798
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0269
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Dok	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.131059
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6225
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4901
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoma, Non-Hodgkin	HuGE Navigator Gene-Phenotype Associations	1.0	null
outer CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91476
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95729
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6833
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89123
Blood-platelet	Tabula Sapiens Gene-Cell Associations	1.0	1.62091
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7267
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CHRNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8056
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.356
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2559
RRM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8246
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7083
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.311
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84222
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1693
Brain Lower Grade Glioma_LGG_TCGA-HT-7880-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17248_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.55777
collagen	Phosphosite Textmining Biological Term Annotations	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.722
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3368
megakaryoblast	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3431-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51448
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7479
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3485
blood plasma	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	1.87887
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Blood plasma	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.78282
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2338
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2924
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80423
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.713
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.8838
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.5309
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	1.62691
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09643
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.35722
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845615
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27606
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11524
Perturb_17249_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.0448
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902556
SPI1	ChEA Transcription Factor Targets	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08721
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
spleen	HPA Tissue Protein Expression Profiles	-1.0	-2.18331
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87992
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14388
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEL9217	CCLE Cell Line Gene Expression Profiles	1.0	2.70905
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.241902
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51119
HCC364	CCLE Cell Line Gene Expression Profiles	1.0	2.04009
MXI1	ENCODE Transcription Factor Targets	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1521
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.939336
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833993
PMC6962646-mmc2.xlsx-StemCell_Genesets_2018-GSX1_GSX1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the liver	GWASdb SNP-Phenotype Associations	1.0	0.267889
Abortion, Spontaneous	HuGE Navigator Gene-Phenotype Associations	1.0	null
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.713
Eye degenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6234
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.516
arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.78282
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.62829
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
retinal degeneration	GWASdb SNP-Disease Associations	1.0	0.38559
BJHTERT	CCLE Cell Line Gene Expression Profiles	1.0	1.41281
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.96333
bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.78282
Lung adenocarcinoma_LUAD_TCGA-38-4626-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.9232
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3181
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.772
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.900867
Lung adenocarcinoma_LUAD_TCGA-55-6970-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	2.28596
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5421
Asthma and major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
coronary artery disease	GWASdb SNP-Disease Associations	1.0	1.56253
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.963774
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899715
Superior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.277
acetylcholine receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6495
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040157
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hepatitis	GWASdb SNP-Phenotype Associations	1.0	1.73733
Immunoglobulin V-set domain	InterPro Predicted Protein Domain Annotations	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9853
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8646
integrin	Phosphosite Textmining Biological Term Annotations	1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
src-family-kinases	Phosphosite Textmining Biological Term Annotations	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2172
macular degeneration	GAD Gene-Disease Associations	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3919
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4873
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.66033
GSE148692,GSE148695_5_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.4919
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4034
grb2	GeneRIF Biological Term Annotations	1.0	null
CCNQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80697
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPHA4	Kinase Library Tyrosine Kinome Atlas	1.0	98.55
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32551
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OX-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881979
LYN	Kinase Library Tyrosine Kinome Atlas	1.0	98.75
NPrEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891946
Human - Fetal Development - L2 - Muscle-Megakaryocytes	HuBMAP Azimuth Cell Type Annotations	1.0	null
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ER to Golgi transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.423
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9603
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9582
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	2.23471
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NH-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2932
diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.69843
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29849
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981551
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7D0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41444
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_2_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5602
Perturb_12555_Mut_Atxn1_SRP148491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.00197
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8757
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8336
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.188
RERF-LC-FM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898464
membrane part	GO Cellular Component Annotations 2015	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.017
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66226
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23234
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.67
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5839
Tic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48356
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5265
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21634
GATA2	ChEA Transcription Factor Targets	1.0	null
PMC8904372-10552_2021_1543_MOESM1_ESM.doc-0-SALL4_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.2842
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05574
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.555
age related macular degeneration	GWASdb SNP-Disease Associations	1.0	1.16047
IKZF1_01_138	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.22541
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40025
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6665
recruits	GeneRIF Biological Term Annotations	1.0	null
Secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BCL3	ChEA Transcription Factor Targets	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3433
FAM168B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7005
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.236916
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35664
EPOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96372
Arthritis, Psoriatic	HuGE Navigator Gene-Phenotype Associations	1.0	null
ht55	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19026
Perturb_14927_Mut_Atxn1_SRP148491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.75028
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7043
Bpe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.0979
LYL1	ChEA Transcription Factor Targets	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3972
SOX9-26525672-CHIP-SEQ-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.086
GSE146074_1_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089838
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93426
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.0726
J82	CCLE Cell Line Gene CNV Profiles	1.0	1.70252
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_1_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5550424-41467_2017_212_MOESM4_ESM.xlsx-Hematlas-Genesets-GSX1_GSX1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.39929
bladder	GTEx Tissue Gene Expression Profiles	-1.0	-0.898226
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5133
Platelet degranulation	Reactome Pathways 2024	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTK	Kinase Library Tyrosine Kinome Atlas	1.0	97.68
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966351
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25943
Merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.256
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56106
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	2.04829
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27606
Premature aging_Skin fibroblast_GSE10123	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.21461
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.867624
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Superoxide dismutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.96134
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.19772
EPHB3	Kinase Library Tyrosine Kinome Atlas	1.0	97.22
laminin-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977222
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939138
JHESOAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.85578
Cutaneous lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46486
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966351
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arthritis	GWASdb SNP-Disease Associations	1.0	1.20464
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1667
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
EMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44225
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49H-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphotoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.577
Mature chylomicron	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.707
Perturb_1393_KO_Rad9_SRP214104	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.98224
platelet alpha granule membrane	GO Cellular Component Annotations 2023	1.0	null
Cardia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10861
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20109
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9478
AKT1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2699
carbohydrate metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.69843
TAF15_02_163	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.08746
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood platelet	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
viral infectious disease	GWASdb SNP-Disease Associations	1.0	0.445426
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A7U0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5413
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.50282
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colo-678 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
496100400_PCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11151
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1655
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939138
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.154817
vagina	GTEx Tissue Gene Expression Profiles	-1.0	-0.898226
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2721
HCK	Kinase Library Tyrosine Kinome Atlas	1.0	97.61
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.6207
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-LI-A9QH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCAPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99011
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34856
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57206
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2992
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9692
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38324
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.39929
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06271
SNU-216 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8993
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WR-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83017
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN464	CCLE Cell Line Gene Expression Profiles	1.0	1.5542
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.017
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06466
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.34504
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939138
GRB2	Hub Proteins Protein-Protein Interactions	1.0	null
GSE242083,GSE242098_3_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
grb2	Phosphosite Textmining Biological Term Annotations	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0656
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939138
dna-binding-proteins	Phosphosite Textmining Biological Term Annotations	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40025
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1442
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRMS	Kinase Library Tyrosine Kinome Atlas	1.0	99.26
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60389
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53369
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1578
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
Vasculitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.696
Perturb_16671_KO_Zfp36l2_SRP310261	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
LN319	CCLE Cell Line Gene Expression Profiles	1.0	1.43629
GSE231891_5_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein-interaction-mapping	Phosphosite Textmining Biological Term Annotations	1.0	null
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.318
decreased heart rate	MGI Mouse Phenotype Associations 2023	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9166
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76485
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7712
SOX2	ChEA Transcription Factor Targets	1.0	null
Brush cell (Tuft cell)_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3349-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22166
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0392
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.178
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9487
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44851
agonists	Phosphosite Textmining Biological Term Annotations	1.0	null
MKN45	CCLE Cell Line Gene CNV Profiles	1.0	1.5001
Platelet alpha granule membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-73-4676-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07033
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23932
496100490_HIP_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26485
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5822
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898464
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91984
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0571
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3547
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04079
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5187
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6541
adaptor-proteins-signal-transducing	Phosphosite Textmining Biological Term Annotations	1.0	null
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.969
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6537
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2323
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7972
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.101163
SOX11	ChEA Transcription Factor Targets	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BmN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6747
Stevens-Johnson syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.328
Brain Lower Grade Glioma_LGG_TCGA-P5-A731-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.30665
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51784
platelet alpha granule membrane	GO Cellular Component Annotations 2025	1.0	null
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.184778
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.80497
SLR24	CCLE Cell Line Gene Expression Profiles	1.0	1.68004
NCIH1838	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65619
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05269
Brush cell (Tuft cell)_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30035
bone marrow	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.318
mRNA_NR0B1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
mek	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3016
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8404
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCA4	ChEA Transcription Factor Targets	1.0	null
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21975
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78854
Sarcoma_SARC_TCGA-MJ-A68H-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.318
Gata-6_KO_GDS4782_330_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
cos-cells	Phosphosite Textmining Biological Term Annotations	1.0	null
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	1.38325
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
TC-71 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39339
mp88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073803
JJN3	CCLE Cell Line Gene CNV Profiles	1.0	1.77752
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6355
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0571
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
acetylcholine receptor regulator activity	GO Molecular Function Annotations 2025	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_3_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54537
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane	Phosphosite Textmining Biological Term Annotations	1.0	null
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.334497
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6708
OGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35072
membrane	GO Cellular Component Annotations 2015	1.0	null
496100587_FWM_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0783
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.32152
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9034
TBP	ENCODE Transcription Factor Targets	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897677
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897677
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MT-ND4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28111
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9066
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57458
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRB2	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.65477
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01913
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05574
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0324
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05574
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.736
Lung cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
mitogen-activated-protein-kinases	Phosphosite Textmining Biological Term Annotations	1.0	null
hematopoietic stem cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33147
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23234
Kidney Chromophobe_KICH_TCGA-KO-8407-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EO-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FRK	Kinase Library Tyrosine Kinome Atlas	1.0	99.43
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17085
marrow cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MDAMB231	CCLE Cell Line Gene CNV Profiles	1.0	1.36163
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Schizozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.767
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9467
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
docking	Phosphosite Textmining Biological Term Annotations	1.0	null
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4147
SW1990	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01792
GSE97870,GSE97871_1_v_2_ctcf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
colo320dm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
Arntl	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5606
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chronic tic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5923
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33413
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Integrin alphaIIb-beta3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
HS695T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45554
glycosylation	Phosphosite Textmining Biological Term Annotations	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0571
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
TEC	Kinase Library Tyrosine Kinome Atlas	1.0	98.31
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12283
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27606
NB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32658
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21899
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2247
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.07405
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.1379
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1619
lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.274608
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2959
PMC11338781-Table1.XLSX-ST_2-Table_S2_The_two-sample_Mendelian_randomization_results_of_blood_GRN_and_JIA_GWAS_This_table_only_show_exposures_with_statistically_significant_MR_p-value_0_05_13_640_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.976
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8699
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81719
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1113
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54459
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.154817
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_133_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17781
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87073
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03855
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7559
GSE180200,GSE180201_12_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5765
disease by infectious agent	GWASdb SNP-Disease Associations	1.0	0.341103
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.933261
LN382	CCLE Cell Line Gene Expression Profiles	1.0	1.44222
NCIH1092	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60796
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
Adrenocortical carcinoma_ACC_TCGA-OR-A5JI-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8321
SP in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985959
Membranous glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.017
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978496
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9256
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2171
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4427
Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02096
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
LTK	Kinase Library Tyrosine Kinome Atlas	1.0	98.14
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975907
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7831
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the macula	GWASdb SNP-Phenotype Associations	1.0	1.01377
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	84.1532
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1458
EPHA1	Kinase Library Tyrosine Kinome Atlas	1.0	99.3
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2681
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76005
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33716
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Aa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4174-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851929
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47795
GSE158834_10_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98027
IGR39	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68268
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4761
HLC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11454
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3333
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87249
HK2	CCLE Cell Line Gene Expression Profiles	1.0	1.85558
Sickle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular response to acetylcholine	GO Biological Process Annotations 2025	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.548
ZNF347	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93872
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8312
musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.78282
k562-cells	Phosphosite Textmining Biological Term Annotations	1.0	null
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9344
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ovarian fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.241902
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922908
Nuclear proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.609
HMC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KLHL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68655
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_OE_GSE43730_684_human_MCF10A cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.7503
ALK	Kinase Library Tyrosine Kinome Atlas	1.0	99.59
Glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.017
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30035
Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66226
Spleen_CT1_Platelet	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.950769
CAL148	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78955
ETS1	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-3B-A9HL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.898226
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39825
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0361
GATA2	ENCODE Transcription Factor Targets	1.0	null
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98514
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097033
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3163
secretory granule membrane	GO Cellular Component Annotations 2023	1.0	null
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
hepatitis b	GWASdb SNP-Disease Associations	1.0	1.81775
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2672
Parasitic ectoparasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.30275
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALE	CCLE Cell Line Gene Expression Profiles	1.0	2.13624
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7576
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09883
Adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.527
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2699
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.070627
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05971
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9303
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8626
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.476801
degeneration of macula and posterior pole	GWASdb SNP-Disease Associations	1.0	1.16047
MutLbeta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00881
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33091
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H-508	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
Brain Lower Grade Glioma_LGG_TCGA-DB-A64R-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Diabetic cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
blood	Phosphosite Textmining Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4403-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.586
GSE120336_1_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Macular Degeneration	dbGAP Gene-Trait Associations	1.0	0.461565
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1325
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1262
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.235071
COLO201	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
signalling	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.527
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LCK	Kinase Library Tyrosine Kinome Atlas	1.0	96.72
Colorectal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73619
Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6523
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40025
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
lung	GTEx Tissue Gene Expression Profiles	1.0	0.997984
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.749
GATA1	ENCODE Transcription Factor Targets	1.0	null
SNX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45506
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAMD4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23147
Neutrophil extracellular trap	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.441
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Mal de Meleda	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1812
Perturb_16947_OE_Mir181a1_SRP359086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.40804
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3952
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2964
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5183
inner SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.956075
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.098
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.33673
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3614
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33716
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85111
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.558
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
EPHA5	Kinase Library Tyrosine Kinome Atlas	1.0	97.99
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7696-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GMS10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8661
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8381
EP300	ENCODE Transcription Factor Targets	1.0	null
TOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92548
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	162.03
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3919
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07283
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23967
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_1_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
t30-blood-rna_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	2.24687
retinal disease	GWASdb SNP-Disease Associations	1.0	0.259601
ER membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.326
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17468
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EPHA6	Kinase Library Tyrosine Kinome Atlas	1.0	98.88
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.9623
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269521
post-anaphase microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
testis	HPA Tissue Protein Expression Profiles	1.0	1.30612
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04733
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897255
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8583
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0571
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981551
src	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
s-transferase	Phosphosite Textmining Biological Term Annotations	1.0	null
gp2d	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
Monilethrix	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7038
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1864
myeloid progenitor cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7175
EOL-1-CELL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5791
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64013
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	1.42486
MIA-PACA-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.5965
Integrin alphav-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0848
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20255
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPHA7	Kinase Library Tyrosine Kinome Atlas	1.0	99.43
ETS1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3EP-11A-12R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00184
Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
map	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Multimerin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80549
disease	Phosphosite Textmining Biological Term Annotations	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9526
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6515
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.373859
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941162
Platelet alpha granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SW1990	CCLE Cell Line Gene CNV Profiles	1.0	2.44328
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6319
dg1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22287
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939138
SW620	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64427
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colon sigmoideum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11132
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6397
Loose anagen hair syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A520-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898781
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7137
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1307
Adrenocortical carcinoma_ACC_TCGA-OR-A5KT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
WM278	COSMIC Cell Line Gene Mutation Profiles	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04191
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin	HPA Tissue Protein Expression Profiles	1.0	1.30612
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A7U6-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2814	CCLE Cell Line Gene Expression Profiles	1.0	1.86857
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2683
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.2274
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane-glycoproteins	Phosphosite Textmining Biological Term Annotations	1.0	null
MOLT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5714
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CL-34	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
CBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08332
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9509
Perturb_1429_KO_Prkcd_SRP386893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.40388
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63637
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039475
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5111
Brush cell (Tuft cell)_Small intestine_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.311
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97433
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.12237
Retinal degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1122
decreased heart rate	IMPC Knockout Mouse Phenotypes	1.0	null
Age related macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.458
HCC1187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macular degeneration	GWASdb SNP-Phenotype Associations	1.0	1.01377
Li	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
eye disease	GWASdb SNP-Disease Associations	1.0	0.155839
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056011
cervix uteri	GTEx Tissue Gene Expression Profiles	-1.0	-0.898226
Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.09637
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5822
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56783
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.914
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060526
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.321
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.216
abortion, spontaneous	GAD Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tertiary granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.294
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2228
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2691
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_1_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.0699
Lice infestation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.726
Perturb_16642_OE_Chmp2b_SRP238748	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.51595
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.538
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01352
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
acquired metabolic disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.69843
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10875
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7152
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.202
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.4875
MCF7	CCLE Cell Line Gene Expression Profiles	-1.0	-2.55086
Respiratory system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.933
