association	dataset	threshold value	standardized value
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5984
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0009
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53164
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9504
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9885
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9278
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4943
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.79
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5856
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.798
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8646
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9558
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9816
CRCGN015_MCF10A_48H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1018
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30908
CRCGN016_MCF10A.WT.HP_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24444
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:E08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07072
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.685184
CRCGN015_MCF10A.TP53.M_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39274
CRCGN017_MCF10A.TP53.M_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22385
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9277
CRCGN009_HEPG2_24H:B18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03062
TA-19-YA45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263802
CRCGN009_HEPG2_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02263
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5489
CRCGN009_HEPG2_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0862
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.516
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8203
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0676
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1587
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6144
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8971
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47395
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3301
CRCGN015_HEPG2_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00595
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3488
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2943
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1087
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70825
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79075
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13235
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8102
NB-58-SA13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284736
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2968
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1781
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4704
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2691
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4093
CRCGN013_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13359
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.46929
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8458
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8271
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47619
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.656
CRCGN009_HEPG2_24H:O16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2538
Blood-platelet	Tabula Sapiens Gene-Cell Associations	1.0	0.121662
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8286
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6833
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.1948
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40431
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.77115
FA-56-WH26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328001
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.15119
CRCGN014_HEPG2_3H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01945
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8691
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7258
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3219
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4474
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3935
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.91
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1508
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9256
CRCGN016_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36262
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.89653
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2085
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3016
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13711
CRCGN015_MCF10A_48H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14375
CRCGN009_HEPG2_24H:I15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06831
CRCGN011_HEPG2_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23705
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0543
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7152
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79033
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8175
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09123
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1925
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1655
CRCGN014_HEPG2_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09965
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	9.68808
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3614
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.928
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1122
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.22798
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1895
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0426
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27983
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29971
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.204
XB-35-TO54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289074
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5347
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2743
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.63
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4725
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.65346
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.18544
BA-60-DR11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20273
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26276
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7965
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4326
CRCGN015_HEPG2_48H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24763
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0713
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.449081
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1113
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.364
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45725
CRCGN015_HEPG2_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11554
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	11.9357
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5664
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07255
CRCGN014_HEPG2_24H:F18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29386
CRCGN015_MCF10A.WT.HP_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11047
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1253
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.88016
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53398
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.8817
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.367
CRCGN015_MCF10A_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30829
CRCGN015_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92297
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.003
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.546
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3368
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.976
TC-45-JH72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303157
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.511
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	11.6058
QA-98-TQ46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349106
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4501
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4013
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40949
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6823
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35309
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3374
CRCGN015_MCF10A_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58264
CRCGN008_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1685
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.12568
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5299
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.75171
YC-45-JD42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254844
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79102
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57285
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8699
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1125
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4101
AA-90-YI00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227784
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.33035
AE-38-LX10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271282
CRCGN017_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94905
JC-52-RH51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207481
MF-20-QI53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288657
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6213