association	dataset	threshold value	standardized value
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3044
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69916
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43299
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.634222
BRD-A41250203_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35281
JUP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61831
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06309
Kidney Chromophobe_KICH_TCGA-KL-8342-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HV-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47M-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49682
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.891822
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59992
BRD-K76015448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54339
NUF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00403595
BRD-K26208451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81081
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05594
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
BRD-K09720842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57062
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78299
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SH-EP1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
KDM4A	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45448
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.85328
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76162
BRD-K52669647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23892
ZFP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80721
BRD-K61791241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32911
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8152
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993753
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892096
Fetalbrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
nervous system development	GO Biological Process Annotations 2025	1.0	null
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04533
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
spleen	HPA Tissue Gene Expression Profiles	-1.0	-0.960226
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.71045
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921043
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04305
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNASE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52407
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_RMGI_6.0_h_6.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98696
PMC9052432-szac008_suppl_supplementary_table_s1.docx-11-POU3F1_1_POU3F1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13261
BRD-K84239940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04543
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.2457
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25051
REST	ChEA Transcription Factor Targets	1.0	null
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.182666
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11537
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49751
BRD-K81418486_vorinostat_JHUEM2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18956
SLC22A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
BRD-K15427120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18611
HCC38	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63771
Perturb_16115_KO_Map3k12_SRP157873	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.19246
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44781
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BAZ2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K74259627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36015
BRD-K01793276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84659
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CORL47	CCLE Cell Line Gene Expression Profiles	1.0	1.69978
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.14084
BRD-K34602185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02897
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.39428
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44493
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10315
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860965
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4902-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K98496939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16999
BRD-K37740343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68538
SLC37A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37905
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90451
GTEX-UPK5-0126-SM-3GADM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88133
PIP4P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44643
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00551938
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K30563122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70378
PNMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33087
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19295
0317956-0000-3966	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22229548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64447
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45807
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
RMND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51445
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32121
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
16728581-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65616
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06391
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.70298
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84741
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Perturb_16510_OE_Tafazzin_SRP284254	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
acetylcholine receptor inhibitor activity	GO Molecular Function Annotations 2023	1.0	null
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
Hyperphosphatasia with impaired intellectual development syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93347
lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340388
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.4843
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54477
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
BRD-K87537204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68066
PLXNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
EW-7	GDSC Cell Line Gene Expression Profiles	1.0	2.49562
BRD-K98695520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24046
ECE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66715
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02297
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
hsa-miR-3164	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TUBA3C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00506326
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861194
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.437205
BLOC1S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74497
H3K27me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K67319345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09312
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09867
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4254	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06481
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.31895
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8213
UACC62	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62337
MITF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05606
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30859
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09638
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993791
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29011844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27933
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.05359
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43048
IGSF6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573455
GSE256181_2_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWS6-0526-SM-4GIAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K01651394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18324
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36339
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10558
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846533
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6997
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.40163
Mesenchymal progenitor cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K65440031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54081
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.90521
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00934
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2715
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942351
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
TRMT10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84624
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.79295
ANTXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26454
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7349
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K89514545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07432
CSTB_KO_GSE47516_18_mouse_brain (P7 cerebellum, P30 cerebellum, cerebellar granule cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16089
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65687
PMC4905465__F6	PFOCR Pathway Figure Associations 2024	1.0	null
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8037
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT42_Cis-MR_replication_list-eTable_42_Genes_available_for_replication_analyses_in_whiole_blood_gene_expression_from_the_eQTLGen_consortium_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.869503
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069879
BRD-K05250921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63935
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95922469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09411
PMC6491625__F5	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00989
CTTNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36339
BRD-K81543095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78616
LMTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55859
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51897928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48865
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43547
BRD-K91564773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08669
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00137
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50104
BRD-K36170990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41605
BRD-K48676303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43057
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31859
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03009
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
21205295-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39087
GTEX-WFJO-0326-SM-3GIL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K39449566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11769
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43427
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41071
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36201
BRD-K78574327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13999
EP300	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00453594
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6983
BRD-K63803358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62482
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.933732
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49682
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38987
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K13551202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47977
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52993
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZNF624	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76894
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
WDR86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87302
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62718
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041273
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03454
Perturb_1170_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7818
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
Paracentral lobule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57274378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0797
BRD-K20253608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.339
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09503
BRD-K44613656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51589
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30898
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TO175T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69712
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.17377
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36869
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K75853175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30811
BRD-K16247913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79071
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833313
BRD-K92804652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15627
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90845
BRD-K50287215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37487
VSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32345
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1944
BRD-K33510044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37424
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.593
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49233
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ATXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87128
DNAJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73808
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.962745
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921361
BRD-K55147629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59847
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12633
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10523
NCIH446	CCLE Cell Line Gene CNV Profiles	1.0	2.62637
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17315
BRD-K03884263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76054
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7038
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21947
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.32057
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.165407
BRD-K28927944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14261
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945277
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CADOES1	CCLE Cell Line Gene Expression Profiles	1.0	2.4087
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.32748
BRD-K64730221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33052
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35894
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79402882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31998
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20183527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00392
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29425
CRCGN015_MCF10A.TP53.M_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24365
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38989
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22886
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01346
tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.254536
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
Tracheomalacia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
TMED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77397
BRD-K35587518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5046
BRD-K90526956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04848
BRD-K14082333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.89423
stomach_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.831823
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040771
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56305
NB7	GDSC Cell Line Gene Expression Profiles	1.0	1.48965
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.01689
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48694
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ID-00-IC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207342
DESI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30613
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830924
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34281
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.399
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950703
BRD-K99446825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07131
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03921
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
FOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13935
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K41327620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66513
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4856
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12427
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03919
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K33346587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07346
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K47349976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37685
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K90702609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10116
NCIH660	CCLE Cell Line Gene CNV Profiles	1.0	1.42023
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08869
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10094
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Outer acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.605
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899309
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1932
PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.464174
GSE186460_0_v_2_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26226
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16146
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.137085
ZNF534	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77624
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36757
FZD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87386
BRD-K54233340_Dorsomorphin dihydrochloride_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03417
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082285
ZNF32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63099
ELAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
BRD-A47598013_citalopram_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K13781734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14489
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.91714
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89744
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00166
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9877
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39323
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13562
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17285
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZR-75-30	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3846
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24679
MYC-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4965
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GNG11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534191
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67804
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26475
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94888615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28023
TRIM32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31369
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K42582718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74626
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4375
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4166-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K48863591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.83047
BRD-K21864149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52529
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PPFIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66141
FAM118B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32706
SNU626	CCLE Cell Line Gene Expression Profiles	1.0	1.39316
ZFP36L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55757
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47966
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2676
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.071748
Edema	CTD Gene-Disease Associations	1.0	1.20262
BRD-K32617235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55731
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.0549
GALR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85553
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.625476
JAK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00438214
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20781
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molt-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11818
RUNX1	ChEA Transcription Factor Targets	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18113
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34985
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.082
SLFN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22435
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPPL2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00707891
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
IFFO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40232
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26532
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070042
EW8	CCLE Cell Line Gene Expression Profiles	1.0	1.99047
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87209752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37567
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36653
pioglitazone_mus musculus_gpl2897_gse8806	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306444
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.02128
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825952
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A00680357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48413
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78127
BRD-K16526787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.8444
TXNDC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42981
CDKN2AIP-20523734-CORTICAL-NEURONS	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5407
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928717
GHITM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49951
BRD-K30065842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59367
HDAC6	ENCODE Transcription Factor Targets	1.0	null
PMC12685885-Table1.xlsx-Table_S9-Du_PanCancer_SOX6_TrsFib_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23251
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4724
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911253
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.22879
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-X62O-0826-SM-46MW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
H2AC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07012
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00998
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09311
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.5027
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275094
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.41402
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981963
GSE81193_3_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06725
ZFPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98728
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990993
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41389177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43566
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NCI-H2110	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26742
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	194.166
PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D4_vs_D9-FDR_0_05_logFC_2_RPKM_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4627
ADAM17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557193
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857432
BRD-K91796483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00773
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10449
AP1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95469
HAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58128
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01985
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
BRD-K94573433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34246
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20089
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79588
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11949
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10759
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
KG-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13436682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62754
GID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.823
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855994
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8706
BRD-K34739404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40754
TANK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480304
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K52416366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36285
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44189
OLFML2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
769-P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIRT4_KO_GSE56321_391_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03632
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900971
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31575
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1863
18223198-TableS3	GeneSigDB Published Gene Signatures	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	2.17897
BRD-K93601851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23348
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PITPNM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605313
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80085
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17901
NAXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30545
MAP7D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00905
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76884
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280576
GTF2H5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76924
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10201
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849473
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28736
Kidney Chromophobe_KICH_TCGA-KN-8429-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebellar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13036
CAKI1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.38439
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63903
subpallial amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03242
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10094
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	2.65495
BRD-K24907498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05981
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077696
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65219
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_207_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29399
BRD-K99749624_S1003_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59578
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13062
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28146
PMC11383936-41598_2024_71738_MOESM6_ESM.xlsx-DEPs_LMS_vs_HC-Unnamed_4_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	13.7848
dolichol-phosphate-mannose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111035,GSE111040_8_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HMOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00292606
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41946
ST6GALNAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6251
Perturb_13763_KO_Uqcrq_SRP284268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.0236
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059259
BRD-K93484038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0858
hsa-miR-4741	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825952
BRD-K43159427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34108
GSE237040_2_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RUSQ-0426-SM-47JWR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0668
TBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30358
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00449
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04191
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93014
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1606
SLC5A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00619953
TMCO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46299
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15305
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70407
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K02641134_2-(4-(tert-butyl)benzamido)-4-chlorobenzoic acid KUC105998N_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	2.02882
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49429
GAREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7601
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68536
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11355
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49006
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62852
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01391
BRD-K43271856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46108
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23284
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.359
GTEX-XUZC-0626-SM-4BOPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.8838
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45527
BRD-K72175798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.01894
ZNF808	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05247
BRD-K75551005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51933
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38568
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74021
Colorectal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
CSTB_KO_GDS5090_200_mouse_Cerebellar granule cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21852
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
C2orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60171
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35442564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47418
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Salivary_Gland-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.696791
BRD-K05096562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.25849
MFSD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05507
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.5899
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.86631
t62-spleen_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.18877
TBP	ENCODE Transcription Factor Targets	1.0	null
ENTPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08156
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.859074
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847659
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28418
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988153
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55033
Perturb_15805_KO_Atf4_SRP350242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.1635
ERV3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34765
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7586
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999424
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82357
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OXER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71094
RBBP5	ENCODE Transcription Factor Targets	1.0	null
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.839699
GTEx Ovary 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-4.49327
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreas-pancreatic delta cell	Tabula Sapiens Gene-Cell Associations	1.0	0.890079
HCC70	DepMap CRISPR Gene Dependency	1.0	5.4252
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.593
DENND4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57904
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052618
NPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65517
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99352
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0841
TMEM222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56161
BRD-K48689133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30247
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BFTC905	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60342
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16146
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47327
19621087-Table1d	GeneSigDB Published Gene Signatures	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040916
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38769
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21947
BRD-K30738175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.28766
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67241
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53773
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATR_knockdown_140_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.9051
CRCGN016_MCF10A.TP53.M_24H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30996
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18281
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K60758969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79163
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.27338
Perturb_16102_KO_Map3k12_SRP157873	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.271
PMC4858740-ncomms11473-s2.xls-HAdV-D9_cr1b_Library_1-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9745_KO_Ucn3_SRP043013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.95838
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45212
NR4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57559
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
YTHDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69971
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40885
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03111
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998282
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27397
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
Perturb_4354_KD_ERK3_SRP238353	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10221
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.962907
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.019
BRD-K59606563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12603
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23914
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ST8SIA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00562848
meteneprost-7504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RALGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29013
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K21423050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03169
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Perturb_11862_KO_Yap_SRP186725	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.62334
PMC3348545-NIHMS263168-supplement-3.pdf-196-ZFAT_ZFAT	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K96416345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16909
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CAMA1	DepMap CRISPR Gene Dependency	1.0	2.69281
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1607
BRD-K02708799_GSK-1059615_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amorolfine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2722
CCNY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02165
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2913
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SIRT4_KO_GDS4823_505_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LCORL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23731
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47307
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K73048554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48019
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN013_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18433
BRD-K82362034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52354
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.13041
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01234
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.98013
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33309
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50271
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.83298
NUGC3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73
lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316224
BRD-K25982056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38382
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.4246
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.741
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K71607378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12465
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69824
GSE126127_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NPEPPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10098
BRD-K91885806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70691
EP300	ENCODE Transcription Factor Targets	1.0	null
medial septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25561
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70707
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MS (Multiple Sclerosis)_CNS - Spinal Cord (MMHCC)_GSE842	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.25984
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.35965
BRD-K34489843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4208
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51296
FOXH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04543
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77463
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.91714
BRD-K30361950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02221
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947198
BRD-K44292107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84238
PGM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00267
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23424
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41903
BRD-K91820608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73394
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K74712962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35678
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93301
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02539
Perturb_14684_KO_Prkaa1/Prkaa2_ERP006813	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.08334
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31302
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9046
Basomedial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08895
FAM111A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90827
SART3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14623
DDX53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27041
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67256
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62527
RH-1	GDSC Cell Line Gene Expression Profiles	1.0	1.65563
GTEX-O5YT-0426-SM-3MJHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
TRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9685
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.823479
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K21433749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14384
BRD-K10640729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27383
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87948
BRD-K73637411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37227
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.521
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IGSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37193
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
LPS510	DepMap CRISPR Gene Dependency	1.0	2.55127
BRD-K95121261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28646
BRD-K35422614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38509
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3637
BRD-K67979704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44201
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.48538
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.5273
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.56143
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46533
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27382
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
IRF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31248
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K29130550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43139
CHPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76109
MAP4K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40374
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30098
PPP1R16A	Pathway Commons Protein-Protein Interactions	1.0	null
Melanotroph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
ZMYM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51593
BRD-K02315086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.016
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.23802
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SCOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30805
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MEG-01	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232039
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12554
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4908-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09105
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959835
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0902
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92707
FAM136A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19352
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RAB40C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93859
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.34664
BRD-A13122391_16-HYDROXYTRIPTOLIDE_A375_24.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.884136
Turner Syndrome_CNS - Brain (MMHCC)_GSE1606	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.73336
FLI1	ChEA Transcription Factor Targets	1.0	null
BRD-A71390734_4-Demethoxydaunorubicin hydrochloride (65)_JHUEM2_6.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K09450441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34461
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2109
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30558628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49682
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39036
Perturb_14833_KD_Scr_SRP017110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873653
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16201
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K24494475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66063
UPF1_Deficiency_GDS2781_188_human_HeLa cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.2236
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03935
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLFN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16626
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96508
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.938008
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13308
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06823
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3175	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Infantile neuronal ceroid lipofuscinosis_Brain_GSE6678	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.51291
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71063
DDX55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04935
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61086
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338545
COX7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16021
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867195
anchored component of membrane	GO Cellular Component Annotations 2015	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18384
BRD-K46152990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08578
LPXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04365
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10022
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13854
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
Perturb_14216_KO_Igf1r_SRP081104	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.29613
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54477
BRD-K31896531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.73808
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
BRD-K76205745_Losartan Potassium_RMGI_6.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40802
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32019
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K25905181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18955
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919106
Rhinencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	174.455
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71483
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K41025232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7688
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7543
ERBB2_druginhibition_8_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.64328
BRD-K09995054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15752
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27545
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2833
ZNF708_01_130	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.17562
GSE210101,GSE210114_4_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39752756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15214
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23473
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084063
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67142
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957678
BRD-K38081867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2325
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30237
CDKN2AIP-20523734-CORTICAL_NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43621
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46094
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6992
NCIH1781	CCLE Cell Line Gene CNV Profiles	1.0	2.06099
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8384902-mmc6.xlsx-DEG_ASCL1_3TF_shared-GeneSymbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16061
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Downstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
adrenalgland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.99068
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
RERF-GC-1B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43916
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38685
PMC6491625__F5	PFOCR Pathway Figure Associations 2023	1.0	null
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98701
RK-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
BV-173	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04183
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45053
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14212
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59512
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11524
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10309
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7444
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30613
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11776
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3222
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NMRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00638032
Perturb_16942_KO_Nurr1/Th1_SRP017560	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.51404
TNFRSF13C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507072
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18125
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.956729
KBTBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67722
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Metabolism of proteins	Reactome Pathways 2024	1.0	null
BACH1	ChEA Transcription Factor Targets	1.0	null
PPP3CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607428
SDC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513928
TLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98719
THAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38805
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072709
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Striatum-like amygdalar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06823
NAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19063
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
CPT1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00479691
ZFP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12823
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00917
BRD-K23442578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99224
Perturb_16100_KO_Map3k12_SRP157873	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.36791
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
molecular_function	GO Molecular Function Annotations 2015	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27881
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0986
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13705
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23591
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38831
ITPRID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15805
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K55311609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75305
TT2609C02	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83344
BRD-K33287655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12914
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91354
BRD-K90741031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04887
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K99172965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92873
NFE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44945
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.60886
ECE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62606
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3379
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96479
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51779
Serous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59863
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	176.216
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K13350372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44639
SET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8673
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2978
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57568
PMC8168563-supp_gad.348295.121_Supplemental_Table_S2.xlsx-GSEA_ASCL1_ChIP_Targets-ASCL1_ChIP_Targets_Conserved_in_mose_SCLC_and_human_SCLC_Models_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148252_5_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AMIGO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517606
GLT8D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00416
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104436
BRD-K69082321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98634
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.63212
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.826854
cellular response to acetylcholine	GO Biological Process Annotations 2025	1.0	null
SNCA_KO_GDS4153_444_mouse_Cerebellum - 21 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K30973947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2355
BRD-K19930413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01709
DETROIT562	DepMap CRISPR Gene Dependency	1.0	2.5462
BRD-K75429775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39131
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71501
SNU1066	DepMap CRISPR Gene Dependency	1.0	3.3192
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041308
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27578003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3865
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53089
naltriben-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23197
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43228
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42486
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
NGDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13877
BRD-K11113009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00266
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67723
OGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74179
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95547
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956053
CSTB_KO_GSE47516_678_mouse_mouse cerebellum at P30	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3249
BRD-K16911140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21632
BRD-K45694673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24642
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09135
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422292
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4907-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.7547
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969086
METTL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95019
HCC1187	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01532
BRD-K95768123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18647
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Lung adenocarcinoma_LUAD_TCGA-50-5044-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36099605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78977
BRD-K96619480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07274
Anchored component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61595867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38851
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2731
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57582
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.33583
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NCIH2196	CCLE Cell Line Gene Expression Profiles	1.0	1.64085
acetylcholine receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86155
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03242
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68557
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95441
CUL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4263
STARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11811
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	1.56379
Corticotroph adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36221
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.026
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN012_HEPG2_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14815
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52583
Perturb_790_OE_Foxk2_SRP145105	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23591
PLEKHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92628
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45576113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92143
LBH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77006
G361	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68889
SAMD4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23147
SP1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1731
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.960226
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	209.95
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10678
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11697
BRD-K22633587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93003
DHX38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
D502MG	DepMap CRISPR Gene Dependency	1.0	15.9867
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.454
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52794
BRD-A71933035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02255
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97515
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54388
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Inner acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10677
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.2022
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73681
BRD-K58232861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05894
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.961991
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K31577322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01258
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.79006
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02085
M059K	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8915
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880998
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10398
BRD-K74916896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38639
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9105
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10218
SUCO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82469
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998282
BRD-K25322420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93101
TAF1	ENCODE Transcription Factor Targets	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF280B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00543501
GIPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77349
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03269
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC5013636-ncomms12601-s5.xlsx-TCF3-Groups_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-A15330900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28234
BRD-K91513229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36815
EPHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65462
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38621
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923576
decamethonium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50151
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.67534
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ANGPTL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496593
LRATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82559
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.91178
TCF4	ChEA Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
BRD-K09434518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57339
synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.587618
GTEX-U3ZH-0426-SM-4DXSE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23541
ORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77766
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10828
CCDC103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5438
SAP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02174
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ERI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60162
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944296
TYK-NU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.942259
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34147
Fever	CTD Gene-Disease Associations	1.0	1.08549
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.84093
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16146
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1631
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914684
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.979504
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2176
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-M16762496_S1205_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25429
SCC-9	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53128
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LU99	CCLE Cell Line Gene CNV Profiles	1.0	1.50462
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34371
AOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04487
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31376
stomach_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.950199
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22185
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861587
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00677
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Dorsal endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
BRD-K41033271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29128
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34865
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840263
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34692
BRD-K23112275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25518
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15306
ARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73508
GPSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72494
TAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061013
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_164_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
BRD-K86086851_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30624
BRD-K47164766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15506
BRD-K66248685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08935
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.8037
MAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63045
TRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51952
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19823
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K22778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99048
CLIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67258
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.87975
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039413
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36362
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K73608149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58051
squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469599
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
VWA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74649
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11043
TE9	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51371
GTEX-R55F-1426-SM-2TF53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K20184768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00792
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31629
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	2.59481
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74936
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43048
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ADAM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14073
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30323
SUZ12	ENCODE Transcription Factor Targets	1.0	null
BRD-K54476947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.17913
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
RELB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00840487
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4811
NFE2L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548014
BRD-A05956997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18667
Primary dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00639
ZFHX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572073
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48664
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K27me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K00537235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29032
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56438
NCIH854	CCLE Cell Line Gene Expression Profiles	1.0	1.46584
REST	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_K27me3_17603471_mouseNPC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.22617
PMC12176927-125_2025_6424_MOESM1_ESM.pdf-23-FOXG1_FOXG1	Rummagene Transcription Factor Associations 2026	1.0	null
Type 2 diabetes mellitus_Pancreas_GSE2470	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.5671
BRD-K21386594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21385
BRD-K02987495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33386
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58352
TIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42744
Dendritic lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.153
GPR173	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59446
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18806
PRPSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4474
CD59 antigen	InterPro Predicted Protein Domain Annotations	1.0	null
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07234
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20601
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21722
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06317
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K61134709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02684
BRD-K89175823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31155
Venom apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
STX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01859
ZNF277	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36372
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.593
ACSM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77365
BRD-K38538662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16807
AKAP17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64976
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
BRD-K36782804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33724
BRD-A90462498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11438
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4256
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59268
Perturb_14781_KO_Kansl2_SRP225948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.11436
LPAR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
BRD-K11715561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42399
ZBED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72652
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.88363
MEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81546
BRD-K94312010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18234
GCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84082
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14894
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15396
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3526
PYCR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1783
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07183
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56923
GTEX-QVJO-1826-SM-447C9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
proteasome regulatory particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.204378
WT1	ChEA Transcription Factor Targets	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01995
Perturb_4205_KO_Top1_SRP072888	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.96567
mRNA_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SLC35A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4217
BRD-K45136330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65646
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6047
PEER	CCLE Cell Line Gene Expression Profiles	1.0	1.75521
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22225
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01669916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.078
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	221.481
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39964
AGXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16538
BRD-K36298208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86012
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05651
LU-134-A	GDSC Cell Line Gene Expression Profiles	1.0	1.66497
A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.98489
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74994
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.880513
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
BRD-K71817712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07098
BRD-K52468958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08308
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K89637567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27167
BRD-K76513704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45888
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39763
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.34664
CCL23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00666717
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01646
TBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13388
STAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16191
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72303
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937614
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GZMB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599716
BRD-K87951090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16591
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11552
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.03655
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92089
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324724
BRD-K13119652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47008
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96601
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K57357721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30746
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44068
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89948
UBE3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28077
ACY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54119
UBTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79492
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01179
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61014
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33034
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K16933266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23563
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9997
PDPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20661
ZFYVE26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.452
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80219
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6796-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99894
BRD-K52341452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19673
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K94697940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27548
BRD-K38917645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38958
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ST6GAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38403
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21947
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0445
mRNA_NR0B1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1208
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829245
BRD-K91120514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17247
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5833
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906719
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07962
BRD-K34798837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68291
IREB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10373
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907897
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911234
Serous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-0.960226
MOLT-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
USP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66409
PPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44948
CRCGN016_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02733
ZNF571	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.35478
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K90127324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32891
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.442
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	359.176
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K68949590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01978
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.9696
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Mesenchymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05642
Perturb_2173_KO_Gsdmd_SRP366634	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.51856
SP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07916
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15518
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
levetiracetam_rattus norvegicus_gpl1355_frontal cortex_gds1864	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3202
cellular response to acetylcholine	GO Biological Process Annotations 2023	1.0	null
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829629
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74265
311 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
GTEX-XPVG-0926-SM-4B651	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60224
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76005
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
IMPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A9-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
EW-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08546
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.928201
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956053
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20160406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18997
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09865
Nodal receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.509
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1631
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00149
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94761
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24047785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6489
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15713
binding	GO Molecular Function Annotations 2015	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53864
PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.585625
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	1.42073
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97829
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836071
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52054012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44339
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24312
Bed nuclei of the stria terminalis, posterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02602
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MUC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00420635
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61415
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF540	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12236
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43921
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21168
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K13543055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8333
COV504	DepMap CRISPR Gene Dependency	1.0	2.63858
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45745
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41922
RFX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76958
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05331
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942273
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23448
Cardiomyopathy_Myocardial tissue_GSE5406	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.43998
BRD-K92985620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22494
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
BRD-K66039243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21223
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14498
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.70873
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829027
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.521
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20157
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27804
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2605
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22374
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9788
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
TSA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51294
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42933
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73969
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41501
BRD-K88086273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05069
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23403
BRD-K92356505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53276
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GNE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67782
MKN1	CCLE Cell Line Gene CNV Profiles	1.0	1.86529
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0555
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910258
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.55148
BRD-K03662481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35345
NKX3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58826
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NINJ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479664
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	3.32662
Large_Intestine-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	1.94242
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08147
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S11-Table_S11_MR_resluts_of_brain_pQTL_and_any_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26543702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12006
RBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99555
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909169
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Human - Pancreas - L1 - delta islet cell	HuBMAP Azimuth Cell Type Annotations	1.0	null
BORCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49422
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33833
BRD-K82517280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44631
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BTK_KO_GDS1346_302_mouse_splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78
BRD-K82399478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28922
LS1034	DepMap CRISPR Gene Dependency	1.0	2.44508
COL4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48606
SLC11A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49003
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.13607
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10035
BRD-K80630598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.432
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92743
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26355
TRMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45181
PMC7843730__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K12502280_TG-101348_MCF10A_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TMEM80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26956
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
CRCGN015_MCF10A_48H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22875
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36339
GABRG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00561943
HFE-transferrin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.322
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.034
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1736
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71395
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MOLT13	CCLE Cell Line Gene Expression Profiles	1.0	1.37145
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.3875
GTEX-TML8-0326-SM-4GICN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE140936,GSE140938_2_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03325
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64793
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04108
BRD-K02781189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14905
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52056
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49033
KLF4	ChEA Transcription Factor Targets	1.0	null
TE8	CCLE Cell Line Gene CNV Profiles	1.0	1.57617
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963825
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-1226-SM-4DXT7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77027
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
BRD-K31122616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04092
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78578
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040616
GTEX-WZTO-1126-SM-3NM93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44369
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039691
F2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89496
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21947
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCIY	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49615
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
dexamethasone_mus musculus_gpl5137_gse10900	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VHLL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00613673
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63014
BRD-K28375929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02547
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
RS5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05063
BRD-K64577478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02942
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26005
BRD-K84693638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4616
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	231.407
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61163
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NKX2-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
BRD-K07388954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71312
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844036
BRD-K26383086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90775
H3K9me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCMH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01781
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dendritic branch point	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43916
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT41_Top_cort_prot_cis-MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01127
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF875	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3896
ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056456
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32315
UCMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89114
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66463856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15776
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.21831
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9464
stomach_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.89101
Mitotic arrest phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07026
TCEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71737
BRD-K26263099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43148
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04306
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K27529556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04244
BRD-K25387295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8341
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
HLC1	CCLE Cell Line Gene Expression Profiles	1.0	1.68852
HARS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00397174
BRD-K80240487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02738
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gata4_21746915_heart_lof_mouse_gpl6246_gds3931	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.005183
ZDHHC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62019
APOD_OE_GDS3913_489_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-P4PQ-0226-SM-2S1NK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03861
BRD-K80009401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04723
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.7711
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5066
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.0426
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48182
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07169
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62509
BRD-K00909602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89469
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71337
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K85271599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07858
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28926
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03287
BRD-K41563239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02419
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41409
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881494
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ventropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04821
Perturb_4365_KO_UTX/JMJD3_SRP158713	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77327
BRD-K49211735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41693
RAF1_overexpression_220_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.91455
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62474
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
MAPK14_knockdown_139_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.3443
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K56261053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20378
BRD-K29560103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36496
skin	HPA Tissue Gene Expression Profiles	-1.0	-0.960226
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32468
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7893
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S12-Table_S12_MR_resluts_of_brain_pQTL_and_any_ischemic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99127896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15041
BV173	CCLE Cell Line Gene CNV Profiles	1.0	1.8308
BRD-K41102088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00893
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55404
BRD-K55896279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06383
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Stem cell_Pituitary gland_Human	CellMarker Gene-Cell Type Associations	1.0	null
QSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70651
BRD-K92650579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25665
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03551
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64833
NCI-H2141	GDSC Cell Line Gene Expression Profiles	1.0	1.66664
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87502
CSTB_KO_GDS5090_199_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TDRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8689
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49133
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K18562194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40521
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04653
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75027
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Perturb_16101_KO_Map3k12_SRP157873	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.11284
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50634
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20826
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46064
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31415
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE221577_2_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04785
BRD-K09594570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44705
STAT3	ChEA Transcription Factor Targets	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.03738
BRD-K33702515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91836
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF474	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23856
EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ERBB2_druginhibition_6_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.81254
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE131161_5_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84835
BRD-K16485616_S1122_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K87990170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08022
BRD-K02778838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22177
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.90225
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02344
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06507315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12681
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17328
PMC11079006-41467_2024_48118_MOESM7_ESM.xlsx-E2F6_OE_vs_EGFP_CTR_DE-gene_E2F6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49981566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59812
HSFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6172
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99949
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15148
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN015_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03675
EGR1	ChEA Transcription Factor Targets	1.0	null
BRD-K86073842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03629
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2838
MYH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44772
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832375
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.54859
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2428
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.1959
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17246
BRD-K68223954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49008
Type II spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.593
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30416
NUGC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47961
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89418
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972121
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08352
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	264.991
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SHI1	DepMap CRISPR Gene Dependency	1.0	2.93804
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88186
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25498
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	1.79897
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95412
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972352
ADAM8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00684173
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	168.012
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.779288
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.24514
BRD-K73095160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02646
PSMA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73528
BRD-K80950551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07055
HLA-DRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62541
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27693
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.438282
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BC3C	DepMap CRISPR Gene Dependency	1.0	2.04229
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909761
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.88002
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69522
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86817746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25835
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18678
acetylcholine receptor binding	GO Molecular Function Annotations 2025	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845391
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13092
ACSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84781
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.928687
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
FOXP2	ChEA Transcription Factor Targets	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1703
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03043
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58464
BRD-K43449580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17761
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0153
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
SPPL2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540535
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37482
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907148
hsa-miR-4675	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33316
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28926
Venom gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
EZH2	ENCODE Transcription Factor Targets	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ADGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69737
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00515
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15997
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31488
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
UW228	DepMap CRISPR Gene Dependency	1.0	2.71502
CFAP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57331
CORL311	CCLE Cell Line Gene Expression Profiles	1.0	1.56467
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.2267
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.844
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22829
BRD-K25177502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79988
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22087
Neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02331
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24272
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16538
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06132
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934861
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946954
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03111
BRD-K21635266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43776
BRD-K89900384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08754
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.989334
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K84334677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55015
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45583
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ELN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24352
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8415
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01148617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52615
AKIRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46594
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01052
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.3612
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K86893953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58492
BRD-K10089296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88426
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3681
H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	2.7876
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26337
SZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13585
KDM4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51274
BRD-K19457629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68372
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT44_Phe-MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
RAB7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00413788
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18996
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10632
LIN28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60968
PEX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12123
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6239
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HT-1376	GDSC Cell Line Gene Expression Profiles	-1.0	-1.69708
FOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05467
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88783
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1554
ZNF84	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56812
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20985
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47073
BRD-K34677894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34269
CRCGN014_HEPG2_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37219
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73131
OCUM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HO-1-N-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.83434
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93312
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16384
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1361
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
Post-translational modification: synthesis of GPI-anchored proteins	Reactome Pathways 2024	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5452
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42307
Neuroendocrine cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
MEIOSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97133
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.4827
DMAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10289
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15582
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.74873
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corticotropic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21458
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3155
Small_Intestine-intestinal enteroendocrine cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0310215
BRD-K02759046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13955
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.279307
ALAS2_OE_GDS2118_74_human_Blood	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02186
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26784
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41923
BRD-K85580909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75454
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30206
COV504	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75929
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02413
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
acetylcholine receptor regulator activity	GO Molecular Function Annotations 2023	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ChIP_MYC_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36833
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22505
BRD-K54478142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58131
PPARGC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3911
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12252
BRD-K16485616_S1122_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K07348252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68727
BRD-K48046422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68102
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.264155
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81704
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902411
BRD-K19039785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17561
BRD-K83872468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08145
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE214212_3_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
M059K	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39813
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16503
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52622
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03876
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ACC3	BioGPS Cell Line Gene Expression Profiles	1.0	1.11559
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K82638914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2707
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.962837
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845677
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27036
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51507
Tracheal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
LAMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11024
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13475
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
BRD-K44643967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35299
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.928911
k562clones	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PROCR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00356731
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.593
BRD-K34931072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54473
BRD-K19418944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1163
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
Lung adenocarcinoma_LUAD_TCGA-97-8177-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10358_KD_Ascl1_SRP340223	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.2227
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01985
CBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26393
intermediate stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11776
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.820134
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79738
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
Molybdenum levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
BRD-K84387578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22081
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69033
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	231.406
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10086
CRCGN017_MCF10A.WT.HP_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62445
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K47535493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94126
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48604
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09962
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981879
Perturb_9042_KO_UTX/JMJD3_SRP158713	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21365
Perichromatin fibrils	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.832
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.7317
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35625946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13981
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908788
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.946908
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17663
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934216
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NOZ	DepMap CRISPR Gene Dependency	1.0	2.04676
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.676
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32364
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.87563
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K29597572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31224
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44576
REXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01927
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39815
BRD-K81728234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2746
ENSG00000286190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0636
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24525
NRG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00890826
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22578
BRD-K81725246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20952
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20742
BRD-K00591281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40316
PMC5472759-ncomms15770-s2.xlsx-KIRC_mean_chr8_GISTIC_CN_by_gen-Supplementary_Data_1_TCGA_KIRC_mean_CN_near_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33999
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941917
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NCIH526	CCLE Cell Line Gene Expression Profiles	1.0	2.1567
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831532
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90418
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.46844
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0004
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42255
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52974
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37297
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
system development	GO Biological Process Annotations 2015	1.0	null
PAXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29127
Hemorrhage	CTD Gene-Disease Associations	1.0	1.36418
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	170.11
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19928
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30452
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19535
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7293
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-HSLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4134
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00449
BRD-K70254692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50328
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.861576
CTCF	ENCODE Transcription Factor Targets	1.0	null
MAGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64712
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K31546068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24102
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26908
acetylcholine receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.33634
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.75958
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MKN1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.70002
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832594
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56421
CSNK1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
PRKACA_knockout_266_GSE20984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.00767
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8136
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996409
MAFF	ENCODE Transcription Factor Targets	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03249
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1598
BRD-K44368508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52611
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.06136
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78632
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19068
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	1.43018
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MO-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4621
GSE148252_0_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K38046923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13302
BRD-K73364700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1752
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65234
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10485
BRD-K01512588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88777
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-487-ZNF460_ZNF460	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2676
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05796780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04468
acute lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.317679
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	196.095
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5021
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
MTF2	ChEA Transcription Factor Targets	1.0	null
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
LRFN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51812
GSE148252_5_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2227	GDSC Cell Line Gene Expression Profiles	1.0	1.99218
HARA	CCLE Cell Line Gene CNV Profiles	1.0	1.40244
Pars intermedia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1474
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.3373
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.849246
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93761
NANOG	ChEA Transcription Factor Targets	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1703
BRD-K51502220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12422
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71047
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	1.37302
BRD-K25761766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1721
GSE212312_1_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82131
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24832
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06905
WT1-20215353-NEPHRON PROGENITOR-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37441
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824442
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21168
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41319
Hepatoid adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.974107
GTEX-T6MO-0426-SM-32QOI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34839838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67449
BRD-K56661847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44534
CRCGN012_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19475
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K86330848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47167
Neuron projection branch point	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
BRD-K74126469_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.82879
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891163
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.49185
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15375
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67158
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17416
BRD-K32853527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43394
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02402
KRAP_Deficiency_GDS3528_564_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11387
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03912
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K38035271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34855
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10176
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.975779
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12773
TXNDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30088
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4188
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03861
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9129
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03666
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16259
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061174
BRD-K98934548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20898
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21947
Perturb_14835_KD_Scr_SRP017110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
SF295	GDSC Cell Line Gene Expression Profiles	-1.0	-2.06134
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2464
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN014_HEPG2_3H:K17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1371
BRD-K34980742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19398
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
TBXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88041
hydroxyzine-6660	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMS18	DepMap CRISPR Gene Dependency	1.0	7.14137
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.872986
GTEX-T8EM-0426-SM-4DM7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43592
c-MYC_KD_GDS2526_110_human_BT-474 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE247159_8_v_3_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21654
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S15-Table_S15_MR_resluts_of_brain_pQTL_and_small-vessel_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.18469
STAT3-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27842
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVN-0126-SM-4GIC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K04067194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05323
HCC1187	DepMap CRISPR Gene Dependency	1.0	12.3264
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.1014
ANKFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74456
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03863
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43427
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.446
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT41_Top_cort_prot_cis-MR-eTable_41_Top_cis-instrument_MR_results_of_cortical_proteins_associated_with_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22584
UACC893	DepMap CRISPR Gene Dependency	1.0	3.45647
BRD-K81758631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39182
Pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.891337
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36282114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42566
BRD-K64553072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24345
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1413
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937614
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Renal epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4259
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17427
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.93184
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90687
mantle zone of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01985
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABRE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047617
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10828
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1736
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892264
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32958
acetylcholine receptor inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39696
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.940739
SNCA_KO_GDS4153_529_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RWS6-1926-SM-47JXY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.841181
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04288
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27672
BRD-K04635516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30753
PDXK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651272
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.21316
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.54158
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15305
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866998
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mdamb134vi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
GCSAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43574
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	193.911
BRD-K11625057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5027
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.4223
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31002
foxa1_21151129_mcfdash7_lof_human_gpl10558_gse25315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.21923
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26299
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21869
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02352
BRD-K82765368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53445
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.8637
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1009
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17344
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.851417
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01234
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Post-translational protein modification	Reactome Pathways 2024	1.0	null
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44295
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22389
NASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28812
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ACP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06333
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K11696795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08011
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98631
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881643
PTGES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63084
UNC5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477536
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843481
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73829
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05324
Ovarian clear cell adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34885
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47082
HAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3218
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923025
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937614
KLK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26576
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.43941
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	170.269
SNU-398	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ly-6 antigen / uPA receptor -like	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01337
levetiracetam_rattus norvegicus_gpl1355_hippocampus_gds1864	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K87901124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96482
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.825975
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62178
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08903
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K81475473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03076
CRCGN017_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06481
BRD-K26282994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68587
BRD-K61078510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06556
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.97207
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19071
SIRT4_KO_GDS4823_30_mouse_hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K97298761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45066
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34327
Kinetochore microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.78
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.507
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08246
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-2.33001
BRD-K03371288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47324
GTEX-XBED-1726-SM-47JYO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851495
BRD-K32185628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26777
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82824
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	3.31345
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70678
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.31776
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HT144	DepMap CRISPR Gene Dependency	1.0	3.09836
BRD-K09271653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1524
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910994
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933819
Perturb_4267_OE_GLUT3_SRP256491	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.32289
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59736
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
hsa-miR-3664-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
FBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67381
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961273
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373074
CRCGN012_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36539
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0116
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36583
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5108-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Netherlands-602-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.36458
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2366
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7836
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1797
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15622
BRD-K51787437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11768
NPAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45693
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09483
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNH7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539885
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856006
KP4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46145
CSTB_KO_GDS5090_398_mouse_cerebella	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.02114
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.3099
ZNF484	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49019
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00805
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42293
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
Perturb_130_KD_Tcf7l2_SRP100171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.51203
GTEX-WEY5-0526-SM-3GIKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
PANC-08-13	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38503
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.175014
BRD-K10959171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27911
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7009
HS-578-T	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
Hip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2122
cell part	GO Cellular Component Annotations 2015	1.0	null
HMG20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64166
2313287	CCLE Cell Line Gene CNV Profiles	1.0	1.47288
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855435
BRD-K23204014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09202
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.25207
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6914-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095863
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43719
VPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54107
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SSU72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
KRT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99671
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2813
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837646
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954295
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.1006
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.41067
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5098
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82875
CRCGN010_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09158
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63357
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
anchored component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4053
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3431-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45335
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH2081	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6067
BRD-K02240568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16025
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73177528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04458
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81167
GFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88334
OPM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77745
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50477
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14039
RNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09188
Ethylmalonic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38427
EFNA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498851
AIF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58648
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20826
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02792
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835951
SLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31698
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SH2D2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14153
interneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310783
BRD-K86237035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15481
MARCKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27275
Lung bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
PRKRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05298
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60337
TATDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1014
BRD-K98086832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6557
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86666
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07318
ZDHHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9615
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.12117
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01362004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52869
Vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.976555
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE81193_0_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84210390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59315
CBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55192
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15472
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8283158-mmc2.xlsx-TCF4_NPC-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.00759
GTEX-O5YV-1626-SM-2YUNJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
UQCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57224
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	188.929
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
KYAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96098
PAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17526
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02574
MRE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81558
POLR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98278
organ morphogenesis	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70514
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.896666
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09686
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00645
E2F6	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFG8-0926-SM-3GIKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.779
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053571
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19469
GTEX-UPK5-1526-SM-4JBJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82962
NFIA_Deficiency_GDS2775_640_mouse_Postnatal brains (at P16)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K36252987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07816
KE37	CCLE Cell Line Gene Expression Profiles	1.0	2.2231
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50864
BRD-K46082763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19882
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SNU668	DepMap CRISPR Gene Dependency	1.0	2.34776
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92351
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49966
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7152
BRD-K44416503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7669
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K33573676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57872
anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24711
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K40745976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27938
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34692
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25233
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28717
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
RGL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74888
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
NSMAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70665
Sarcoma_SARC_TCGA-MO-A47R-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27248268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56706
Pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
GTEX-WFG7-0926-SM-4LMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
RFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94713
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.877535
EXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75232
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51373
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932658
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
623 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
KNS42	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68899
SLC39A13_Deficiency_GDS3485_570_mouse_Chondrocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RSC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86179
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02221
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38487270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09846
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07389
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880644
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YH-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7125
TP63	ChEA Transcription Factor Targets	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41059
BRD-K58865204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78464
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07308
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13308
BRD-K24076516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22473
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17655
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K75961186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76948
duodenum	HPA Tissue Gene Expression Profiles	1.0	0.953097
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6469946-aav1472_Data_file_S3.xlsx-PPARG_targets_UP_RNA-Seq_Diet-Supplemental_Table_3_PPARG_targets_up_regulated_in_dKO_vs_CONTROL_RNA-Seq_Diet_FDR_0_1_n_290_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847112
NCI-H64	GDSC Cell Line Gene Expression Profiles	1.0	1.51168
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38786
SLC26A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00337928
Climbing fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77594
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.308
BRD-K08190558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20771
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.43309
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9894
PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-GSE16011_AND_TCGA-GBMLGG_NOT_Human_kinases_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20742
SIRT4_KO_GDS4823_22_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234302
GH4-C1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962483
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927647
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HEY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75274
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970362
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K27me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44215
MLXIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70456
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K27600134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01667
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.870767
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76743
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94423
BRD-K87412446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29376
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6302
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT44_Phe-MR-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_15804_KO_Atf3_SRP350242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.917062
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO684	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88018
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
DPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68674
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	259.944
CRCGN008_HEPG2_24H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18585
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZMPSTE24_Deficiency_GDS3775_506_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24401
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44798
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12832
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90408478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36522
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71973
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27416453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01685
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27921
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90687
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86595
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.742
BRD-K30992744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44071
CL11	CCLE Cell Line Gene Expression Profiles	-1.0	-3.11542
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26513
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5095-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06203932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43052
BRD-K54751614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17423
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8989
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286381
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92897
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1285
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01355
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1781	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
NCIH1573	DepMap CRISPR Gene Dependency	1.0	4.79267
NCIH1341	CCLE Cell Line Gene Expression Profiles	1.0	1.41046
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9098
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.862609
CPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6794
BRD-K94411351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4348
STYK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00847711
HCC1954	DepMap CRISPR Gene Dependency	1.0	3.13945
BRD-K98087319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00727
BRD-K84013239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2517
HCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92884
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855394
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79221878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24836
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.91957
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14913
BRD-K43206373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43327
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00743
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19175
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BCL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92327
BRD-K59657378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82942
BRD-K72386335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53235
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PMC9052432-szac008_suppl_supplementary_table_s1.docx-11-POU3F1_POU3F1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08266
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Perturb_14502_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.17882
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02319
acetylcholine receptor binding	GO Molecular Function Annotations 2023	1.0	null
NSUN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60662
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Autosomal recessive intellectual developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5416
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42485
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22326
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K13901498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23532
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.492572
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69158240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87183
BRD-K49669041_HY-11005_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.844891
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
KE97	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13896
Perturb_4748_KO_Dot1_SRP237928	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.41578
ASCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66053
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36157
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02765
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09974
lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278955
BRD-K38258132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21078
Perturb_8654_KO_ESRRA/ESRRG_SRP304242	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Cerebellar ataxia type 41	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88836
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23099
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24051
Hmgn1_KO_GDS5010_407_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11144
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.943472
BRD-K21412601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97316
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44502
ractopamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58334
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.26702
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K59069382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34171
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.902953
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02725
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05274
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Embryonic brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.011
CAL120	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41824
INTS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10656
TMEM190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31277
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
WDFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36178
ZBTB7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06517
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.942467
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
TP53I11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14801
SCN4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21655
BRD-K63998843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37934
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27175
cell surface	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.255834
BRD-K96096022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10273
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02097
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K91057865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91639
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51278
BRD-K65178566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04758
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32608
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31005
GSE137818_5_v_0_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88537
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12865
TMEM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61246
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1931
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83135
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIA1_KO_GSE54418_260_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82137
ECGI10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50668
BRD-K86269644_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855394
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01977
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17161
NCI-H446	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86744
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K24722502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31799
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07814
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45448
GTEX-XPT6-0426-SM-4B672	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Lung adenocarcinoma_LUAD_TCGA-44-2665-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
Perturb_8601_KO_Pyk2_SRP285527	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.06176
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37199
MYC-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K22139757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12161
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6643
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13647
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3778
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08502
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13806
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05959
BRD-K11095218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69407
ARRDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69579
Perturb_4322_KO_Fmn2_SRP109283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.35096
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	143.429
TFAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55016
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24848
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FAM120AOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80984
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60558
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
FAM83G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12199
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K56488838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12071
BRD-K49529874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12741
Perturb_6393_KO_Ngr1_SRP098816	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.46174
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056458
BRD-K36575476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35217
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33940145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96512
BRD-K67725403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32362
PMC11442894-41467_2024_52678_MOESM5_ESM.xlsx-all_MSC_vs_iMPC-Unnamed_0_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HCaRG_OE_GDS2426_711_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K15236933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3036
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95441
BRD-K19066553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05011
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13274
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.31353
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55636
GTEX-XQ8I-0326-SM-4BOPN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K72424071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29856
ZNF718	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29376
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89363
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21578
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18141
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976502
PPARA_KO_GDS3748_516_mouse_Livers	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69061
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69579
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K93457574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4421
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-661	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K28746174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47223
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333763
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959052
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85895
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.835211
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.26061
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27921
TE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE210101,GSE210114_4_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32719
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11364
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09962
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SPCS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526653
HMGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.943
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63927
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hs-578-T	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6341
BRD-K87647164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16807
IFFO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65541
stomach	HPA Tissue Gene Expression Profiles	1.0	1.13331
BRD-K96120749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55889
CACUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4523
Prostate adenocarcinoma_PRAD_TCGA-HC-7232-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.69701
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40045
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09311
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	2.01298
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06824
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84801
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087552
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06511
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84623
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61025
BRD-K98522669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21387
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04131
BRD-K25649458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10345
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20438
NCIH661	CCLE Cell Line Gene Expression Profiles	1.0	1.52135
BRD-K35383890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5155
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18898
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.861411
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.34134
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45198
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65725
Avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.593
Perturb_6175_OE_Zeb1_SRP187711	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.31168
BRD-K98474331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72457
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24587
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Perturb_13790_KO_Zeb2_SRP066910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.835211
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
basolateral amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.075
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74103290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18602
ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33191
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00016
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03128
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05491
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62762
BRD-K37892442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14553
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62641
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11953091-12035_2025_4695_MOESM1_ESM.xlsx-s5-Supplementary_Table_5_Results_of_the_2-sample_pQTL_MR_on_insomnia_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36109
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44352
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A656-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97869597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02651
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2794
BRD-K85110576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26279
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28828
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848593
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6204
Small_Intestine-intestinal tuft cell	Tabula Sapiens Gene-Cell Associations	1.0	1.10484
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982924
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64736
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02902
mantle zone of VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04821
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33611
15297395-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
ZFP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07033
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1888
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67497
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52684
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1735
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906627
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.67111
BRD-K87884409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03599
BRD-K19045069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98673
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE129725_4_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18948
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256902
EXOSC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90188
MZ2-MEL	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44561
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947362
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54477
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39743
BRD-K81465091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83666
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09506
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K83090041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53311
FOXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5828
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25498
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K38380337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02686
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K88378636_withaferin-a_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
U251MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83486
Perturb_5013_KO_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36275
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15622
t-lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358174
EGFL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09144
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33486
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09604
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839902
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-R55D-0326-SM-48FES	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K52319351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29703
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83977
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849552
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	166.877
EW-11	GDSC Cell Line Gene Expression Profiles	1.0	1.42767
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K27888332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18338
SGF29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41212
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-2.51966
Mesenchymal-epithelial transitioning cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K90460185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56462
BRD-K86293440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3096
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
DLX5_Deficiency_GDS4443_356_mouse_E10.5 embryos otic vesicle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MGAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5328
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZNF674	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80907
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K14210122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93059
RPMI8402	CCLE Cell Line Gene Expression Profiles	1.0	1.46992
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69258
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BCAT-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN011_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38035
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K88620071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03638
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14802
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040593
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12551
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22283
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.4722
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00976973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49689
RPRD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72365
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	2.19664
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33104
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72324
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46184
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10043
single-organism process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31169989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59173
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20742
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41501
Perturb_13979_KO_Dnmt3a_SRP168393	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.4906
SAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1199
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23395
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12117
BRD-K07414059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28641
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.95384
METTL21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2918
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80943
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12709
BRD-K85985071_E3380_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.42
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23144
RAD51	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00616357
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0076
KIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78909
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81915
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SLC18A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45393
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18856
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
FSTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77051
alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.255946
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76581
BRD-K09991945_GSK-3-inhibitor-II_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ATM_knockout_75_GSE23116	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.75136
BRD-K36176998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16623
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81456
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36645
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11243
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12864
PLBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6722
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
BRD-K70379342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10604
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41186
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03887
PMC12122724-41467_2025_60028_MOESM6_ESM.xls-Supplementary_Table_4_Marker_g-Supplementary_Table_4_Marker_genes_of_six_TPIT_tumor_subtypes_TBX19	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8651
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2676
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
APMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.248
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.873058
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34141
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11966
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910387
BRD-K76973159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22832
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24544
GSE202284,GSE202289_1_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acrosomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
TDGF1P3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28345
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
CARHSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15493
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36927
GTEX-S4P3-1826-SM-3K2AL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K20077349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05182
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1928
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00898
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
15902281-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21293
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39178
EW-18	GDSC Cell Line Gene Expression Profiles	1.0	1.85896
BRD-K21196859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03939
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K91575768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26514
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.471
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68672
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03693
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057538
BRD-K45813167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01797
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.9305
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3017
KP-N-RT-BM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57688
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42474
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27015
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.857398
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.637
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
LB1047-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59279
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067507
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
KE-37	GDSC Cell Line Gene Expression Profiles	1.0	2.15178
BRD-K69393995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31236
nervous system development	GO Biological Process Annotations 2015	1.0	null
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11175
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1315
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49006
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7404
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3354
BRD-K32071534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24782
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4305
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03043
acetylcholine receptor regulator activity	GO Molecular Function Annotations 2025	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.51726
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078459
IMPDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45435
BRD-K56276074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2226
MBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93107
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K97183783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02378
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90457
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888324
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31819
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F8-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.831701
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
LU-99A	COSMIC Cell Line Gene CNV Profiles	1.0	2.35236
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ANG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04961
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14308
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47288
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46237
BRD-K53331454_4905-1827_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.44572
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.25273
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62525
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26156776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0129
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00994
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28769
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K59402582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4673
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931416
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K84386253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30553
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2758
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.988679
RHOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19432
IGDCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41634
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02256
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20598
ARVCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97977
TUNAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52221
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82018
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.916
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03952
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.891454
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66394
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31735
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17793
BRD-K65494150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59557
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72385
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21864
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14171
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.95384
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99561
KCNQ5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00494152
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.836919
MBD3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05735
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56123
BRD-K05950670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09953
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11115
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41501
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13562
BRD-K48389907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05617
GSE193588_1_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00897
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54049
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K05357297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5755
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	146.278
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65613
NB4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03061
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45937
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66389
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26163
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CDX2_01_357	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.61064
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975874
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-T3M4_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40485
BRD-K29707171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07636
SPAG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38639
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55919
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03487
RNF103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03498
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88682
BRD-K81120201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95515
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00905
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28068
acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341863
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Diffuse idiopathic skeletal hyperostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
Kidney Chromophobe_KICH_TCGA-KO-8407-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-0226-SM-4DXU8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K53639581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49762
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.32678
BRD-K38571893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29681
BRD-K69668461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11072
lhx8_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.249241
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982212
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S14-Table_S14_MR_resluts_of_brain_pQTL_and_cardioembolic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4905465__F6	PFOCR Pathway Figure Associations 2023	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57308
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942257
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07313
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46281
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J5-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01251
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30871
NCI-H446	GDSC Cell Line Gene Expression Profiles	1.0	3.53237
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08003
lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222938
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09446
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.9293
BRD-K62320774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0289
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	0.876978
BRD-K22380421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06229
BRD-K75779523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17506
CDK20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78344
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	206.178
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	328.561
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7912
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.935429
COL6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87102
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56097
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K35407043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52709
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.743
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882468
MEGF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86926
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.8812
CHOP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20274
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57488
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K55916310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44248
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15967
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70276322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12311
BRD-K03489727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57467
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.12241
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06242
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911234
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.0855
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886955
MDAMB453	DepMap CRISPR Gene Dependency	1.0	5.03591
ARL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3537
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52513
SLC37A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82539
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0345
BRD-K65774385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10513
BRD-K28264750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43709
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24578
BRD-K73330516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06664
BRD-K20984459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14696
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45564
BRD-K81939454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50343
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83564
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46276
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92667
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K78438852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21574
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57941
JURLMK1	CCLE Cell Line Gene CNV Profiles	1.0	1.39213
GLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1701
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91339
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15683
proteasome accessory complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.202009
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ANKRD16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85327
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.75026
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69113
BRD-K32471649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40627
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
OXNAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09164
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79343
BRD-K25199508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2485
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976088
BRD-K31796953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11798
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
GTEX-SE5C-0426-SM-4BRUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
lymphocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.295655
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.842398
HSFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47124
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906627
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K53903639_480743.cdx_HT29_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8522
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13036
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238706
PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381379
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28741
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829874
BRD-K28247259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22383
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4349-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-21867929-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K32706281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52197
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63992
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083387
WT1-20215353-NEPHRON-PROGENITOR-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.3005
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43333
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K90543092_-666_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ABI3BP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066968
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
TET1	ChEA Transcription Factor Targets	1.0	null
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90705
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16392
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67845
AQP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18579
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1533
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55E-0326-SM-48FD2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
MTRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48474
BRD-K44344720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15071
BRD-K20361257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03428
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5508
GMEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12045
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54075
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79481
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.47
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827496
BRD-K85907501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14788
OTUD7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8295
GSE114258_3_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34692
BRD-K06724886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02983
DYRK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67181
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.517
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90244
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919086
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
EZH2	ChEA Transcription Factor Targets	1.0	null
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
HS870T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.92078
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.19837
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01999
BRD-K30917841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53006
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SETD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97153
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12041165-401_2025_2886_MOESM1_ESM.xlsx-Meta_CAA_vs_AD-Genes_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18467
Focal hand dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.01314
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
PGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00628
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36723
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06609
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	82.4404
BRD-K44131977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98253
BRD-K94427708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21913
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S6-Synteny-Syntenic_Analysis_for_29_HSF1-CanSig_8q_Genes_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.948518
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.329
GSE104508_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K27335290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.6815
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65194
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54672
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1462
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62309791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49707
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57117
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03354
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	156.396
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64428
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNFAIP8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77234
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13601
DVL3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0482
BRD-K05251963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12646
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19038
SOX17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557089
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49017
BRD-K25649596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68668
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09023
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00155
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24042
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858394
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8965
ChIP_STAT3_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K33379484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32236
DALRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76292
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K26647686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69997
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21074
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S13-Table_S13_MR_resluts_of_brain_pQTL_and_large-artery_atherosclerotic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GBP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00433771
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36985
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3093
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17182
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05737
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13993
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8971
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCIH358	DepMap CRISPR Gene Dependency	1.0	3.94978
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937614
BRD-K70712801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57977
Small_Intestine-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	0.052498
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216528
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.035
FOXD4L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29084
BRD-K73539077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64637
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69496
BRD-K81471597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32685
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ICC4	DepMap CRISPR Gene Dependency	1.0	3.70665
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40453
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37181
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40371
Vertebral artery occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
BRD-K38131403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29205
BRD-K67740871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46033
GTEX-UJHI-1426-SM-3DB9C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
NCIH446	CCLE Cell Line Gene Expression Profiles	1.0	3.40779
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875649
Tongue-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0334078
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.075
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.1122
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6009
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54866
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.69966
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937614
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.59189
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061315
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF649	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17321
BRD-K14909006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21046
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20046
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066032
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.613835
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FTSJ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00494968
BRD-K54100199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1346
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.43183
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920571
KBTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65355
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36015
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
BRD-K96671994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.61906
BRD-K51157416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5533
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61196
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29925
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4B-Up_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.918957
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01734
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56786
Corpus cavernosum smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
CDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48134
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
GTEX-UPIC-1826-SM-4IHKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829371
GTEX-S4Z8-0926-SM-4AD6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
lateropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01985
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39754
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.2222
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.17661
CAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89167
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_39_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63106
BRD-K88328128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93358
GTEX-XUW1-1126-SM-4BONZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864554
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ZBTB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26647
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70063
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15305
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K25193509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29792
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
BRD-K41202439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34205
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K03312699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40419
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044444
head and neck squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.60893
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09615
PMC7176284-pcbi.1007753.s008.xlsx-2_MYCN-NA_NBL_Multimodal_Genes-gene_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7503
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.03821
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.32678
icSARS CoV_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.29541
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Variola minor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
PMC8168563-supp_gad.348295.121_Supplemental_Table_S2.xlsx-GSEA_ASCL1_ChIP_Targets-Unnamed_1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50551
MAPK1_knockdown_145_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.3312
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35479
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887661
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85007
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.09
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20875
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02911
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.16387
FPGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27672
BRD-K23825243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83257
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.7745
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20046
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09194
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26875
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	186.038
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
OPRL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00527507
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.47171
Mal de Meleda	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.93
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
EPLC272H	DepMap CRISPR Gene Dependency	1.0	2.16769
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CORL95	CCLE Cell Line Gene Expression Profiles	1.0	1.87393
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4837-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055849
GSE145323,GSE145324_1_v_4_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCAR3	BioGPS Cell Line Gene Expression Profiles	1.0	0.974161
nervous system development	GO Biological Process Annotations 2023	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960084
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42694
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14858
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.187
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPTSSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44047
BRD-A39646320_H7270_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BTN3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7059
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6563
TSPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25941
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11737
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61358
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.88407
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055712
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95365728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62095
Phencyclidine abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	2.35503
QSOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39351
SubthalamicNucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.879969
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09763
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL-AF4_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31059
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.29355
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
famotidine-1529	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1817
BRD-K77060313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43676
APOBEC3G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00630956
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	2.9634
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904456
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828618
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982306
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K73582217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73914
Perturb_17409_KO_Kat7_SRP346204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.38183
Septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
SUZ12	ChEA Transcription Factor Targets	1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7396
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24635
NR1I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75007
TIAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571872
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74251
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K09819684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18523
EXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23679
PKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83714
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02143
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51833
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81281620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09475
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1054
GSU	DepMap CRISPR Gene Dependency	1.0	2.0114
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01337
BRD-K51104732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73827
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04561
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61054
HCC15	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49173
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PHLDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.08181
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082872
ADARB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00617532
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28347985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23968
BRD-K37092508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2641
BRD-K35544244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60871
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877241
Adrenocortical carcinoma_ACC_TCGA-OR-A5KT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36997940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08132
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01532
SCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6773
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10501
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16551475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39888
CENPVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73532
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2093
ZNF154	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65156
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10S-01A-22R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68799
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20424
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937614
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	1.0966
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31547
SMCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95653
P4HA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00568347
BRD-A71001587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09057
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.45693
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.735
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33978
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K57205873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79406
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844015
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36498
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23635
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Lassa Fever Virus_8hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.66421
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75851
ZNF143	ENCODE Transcription Factor Targets	1.0	null
BRD-K72580121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94483
GSE103003_1_v_0_zeb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34505
BRD-K62885083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31188
CCDC69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99977
Lung adenocarcinoma_LUAD_TCGA-91-6847-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26969
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3054
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.075
BRD-K06431647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05022
P2RX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83389
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81757
BRD-K97318603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54222
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.092
BCL9L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66214
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46468
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910632
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22262
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0684
CCNH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00351211
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K98008739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.86172
BRD-K80306055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76131
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE90019,GSE90020_1_v_3_phf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07409609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18858
BRD-K34561361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05008
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29613
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835221
BRD-K56188108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77887
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29617
CDKN2AIP	ChEA Transcription Factor Targets	1.0	null
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06967
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29784
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217744
BRD-K68939871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59042
BRD-K63809385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2485
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884306
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K21040167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14083
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44985
COPD - Chronic obstructive pulmonary disease_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE475	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.63617
TSSK1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618865
GTEX-V955-1826-SM-4JBIL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04517
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86739
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44033
ZNF324B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38162
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63618
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77699
PGGT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23757
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
SCAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85093
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1366
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20924
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889466
BRD-K00378498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14136
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39837
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.782
Type 1 diabetes mellitus_T lymphocyte_GSE10586	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.41221
HDAC_INHIBITION - trichostatin A_GDS2452_709_human_Endothelial cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877986
Anemia	CTD Gene-Disease Associations	1.0	1.12254
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044971
BRD-K73523458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03332
MDAMB157	DepMap CRISPR Gene Dependency	1.0	2.05402
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.09777
BRD-K31034311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7907
CALU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61361
AMZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34601
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937614
BRD-K38218737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88182
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17186
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47826
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10315
BRD-K68056389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3577
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53468
Perturb_4193_KO_Mbnl1_SRP057123	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.40065
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
CRCGN011_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83985
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26253
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834258
DCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65705
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17109
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84911
BRD-A26962727_MLS-0425579.0001_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2126
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06925
LHX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61447
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94234
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27209
MEG01	CCLE Cell Line Gene CNV Profiles	1.0	1.59215
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
FBXO33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
CPEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78045
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1092	GDSC Cell Line Gene Expression Profiles	1.0	2.23353
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13475
BRD-K42138859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00041
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09378
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74481
H3K9me3_U2OS_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
c-MYC_KD_GDS2526_112_human_MCF-7 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45808
BRD-K33805195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85197
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5895
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88433
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
GCIY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33863
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948596
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.48204
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	1.0	1.3771
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64639
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.835211
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.256561
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K81619018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15952
SURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41019
BRD-K38111331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22277
HOOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67357
BRD-K64862097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57943
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K21935128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96824
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Brain Lower Grade Glioma_LGG_TCGA-HT-A616-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
3-CPMT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83648
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K96405393_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NECAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5742
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21253
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62171
Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF419	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47005
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Kidney Chromophobe_KICH_TCGA-KL-8335-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88448214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17469
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08502
BRD-K34954550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32615
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0445
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN010_HEPG2_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38638
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0351
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20684
HNRNPCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8028
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09974
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K22591777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14282
LHX8_Deficiency_GDS3254_600_mouse_Newborn ovaries	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterobasal nucleus, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05458
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8973
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K60188481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49344
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45441
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.33706
BRD-K80196706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40717
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.045
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21975
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08194
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HMY1	DepMap CRISPR Gene Dependency	1.0	2.4205
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76821
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
BRD-K26180392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10006
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05634
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1026
motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257237
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.845684
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19932
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16146
ZC3HAV1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3532
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836727
PTTG1IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.952
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79527
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14957