association dataset threshold value standardized value MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.90579 SNB19 CCLE Cell Line Gene CNV Profiles 1.0 1.56431 IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998738 Giant cell tumor cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.901 Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.47139 Secretory granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.671 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04948 HS944T CCLE Cell Line Gene CNV Profiles 1.0 1.4734 DMS114 CCLE Cell Line Gene CNV Profiles -1.0 -2.16604 CLPP_KO_GDS4791_104_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZNF189 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9242 MPZL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.388 LASP1NB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80581 NANOGNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45501 Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OE-01A-11R-A206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29836 Pretectal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07751 HES5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89607 MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.38513 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 EED-16625203-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null SRC_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.158901 Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null ACSF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58383 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.946613 SUZ12-18974828-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.10751 H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 YY1 ENCODE Transcription Factor Targets 1.0 null dorsal lateral geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88545 Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX2 JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Fatty Liver CTD Gene-Disease Associations 1.0 1.03308 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE148066,GSE157787_9_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JVE015 DepMap CRISPR Gene Dependency 1.0 2.44001 Response to antipsychotic treatment in schizophrenia (reasoning) GWAS Catalog SNP-Phenotype Associations 1.0 0.220915 Sarcoma_SARC_TCGA-3B-A9HR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.99667 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63689 principal sensory nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.851503 Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.0845 NCIH28 CCLE Cell Line Gene CNV Profiles 1.0 1.75147 SK-MEL-24 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35569 SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.909885 layer 3 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05949 ICC12 DepMap CRISPR Gene Dependency 1.0 3.35641 ChIP_CTCF_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8547-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null M059K CCLE Cell Line Gene Expression Profiles -1.0 -1.57612 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.76493 Taenia tecta, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63544 Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ENTR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96479 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31702 AFTPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10443 VMRCLCD CCLE Cell Line Gene CNV Profiles -1.0 -1.61623 DMS454 CCLE Cell Line Gene CNV Profiles -1.0 -2.54676 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.52196 GSE145215_0_v_3_krt13_mouse RummaGEO Gene Perturbation Signatures 1.0 null reticular complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 Hindgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.878 H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAB3A_KO_GDS2482_706_mouse_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K27me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCIH209 CCLE Cell Line Gene CNV Profiles -1.0 -1.65397 Spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.733 NFE2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01562 GSE100316_0_v_6_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-511 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 NCIH747 DepMap CRISPR Gene Dependency 1.0 3.27568 Sperm flagellum COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Zona pellucida TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.372 amygdaloid complex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.52184 dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28637 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_TCF7L2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null NUGC2 CCLE Cell Line Gene Expression Profiles -1.0 -2.73255 dorsolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.87662 sperm flagellum GO Cellular Component Annotations 2023 1.0 null Occipital pole TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.698 SKIC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31651 ChIP_EED_16625203 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Intracellular vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 NCIH1184 CCLE Cell Line Gene Expression Profiles 1.0 2.23707 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 PMC6617737-13059_2019_1747_MOESM1_ESM.xlsx-Table_s7_szDMP_OLIG2-Unnamed_22_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null DHX40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22128 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Targets 2022 1.0 null POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.1093 POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6835 spleen GTEx Tissue Gene Expression Profiles 1.0 1.1525 GSE133505_5_v_4_myf6_mouse RummaGEO Gene Perturbation Signatures -1.0 null ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10329 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H2-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.53059 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9834 Acute Myeloid Leukemia_LAML_TCGA-AB-2839-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R9-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.34397 Ectoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.572 POLR2A_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09518 Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Inflammation CTD Gene-Disease Associations 1.0 1.59731 Prostate adenocarcinoma_PRAD_TCGA-G9-6354-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subpallial amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03114 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.062 PMC3117129-mp2010119x6.xls-CRS_Hpc-Unnamed_5_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null Ventral posterolateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68909 Lung adenocarcinoma_LUAD_TCGA-49-6745-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Secretory vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10723 GSE145445,GSE145454_0_v_1_cop1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCIH810 CCLE Cell Line Gene CNV Profiles -1.0 -2.34607 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72977 dorsal peduncular cortex, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46517 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 Larval serum protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.23 lateral part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60989 EWS-FLI1-20517297-SK-N-MC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null FOXD4L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47183 CHD1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_SALL4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.7669 Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dorsal part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54136 Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPMI-7951 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21623 Bipolar disorder GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.622185 Dorsal peduncular area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85481 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.39789 CAPAN1 DepMap CRISPR Gene Dependency 1.0 4.28874 STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null 496100360_FWM_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.39147 H3K27me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE148066,GSE157787_11_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of p1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16179 Acute Myeloid Leukemia_LAML_TCGA-AB-2891-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Hemorrhage CTD Gene-Disease Associations 1.0 1.06698 HSC39 DepMap CRISPR Gene Dependency 1.0 5.50363 GSE143830_0_v_1_trex1_mouse RummaGEO Gene Perturbation Signatures -1.0 null AU565 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.894022 mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null SUDHL1 CCLE Cell Line Gene Expression Profiles 1.0 1.70547 SUPT1 DepMap CRISPR Gene Dependency 1.0 2.71849 HS821T CCLE Cell Line Gene Expression Profiles -1.0 -1.64375 Isolated growth hormone deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.121 ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06488 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 WDR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22282 GATA2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null ZNF24_01_353 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.1716 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2221 NANS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84451 mantle zone of p2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42311 superficial stratum of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32206 MTF2 ChEA Transcription Factor Targets 1.0 null ChIP_SUZ12_16625203 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE92614_1_v_0_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02787 p3 portion of parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69473 Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C75 DepMap CRISPR Gene Dependency 1.0 4.72938 PKDCC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03562 EED ChEA Transcription Factor Targets 1.0 null BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE203158_5_v_15_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null r1 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73604 SUZ12-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.951753 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7026 Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.64436 acrosomal vesicle GO Cellular Component Annotations 2023 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-7889-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUZ12-16625203-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null SLFN13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71959 496100605_TCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.28472 extracellular region GO Cellular Component Annotations 2015 1.0 null Spermatogenic failure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.291 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA1, stratum oriens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54136 brain GTEx Tissue Gene Expression Profiles 1.0 1.57995 sperm part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.12148 Awn TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.421 reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.547 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Granular insular cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.134 CCLP-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.092 SMIM10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76027 CLPP_KO_GDS4791_537_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16165 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Outer acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.772 LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CEBPD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.093 H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.5524 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.10778 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.76098 COLO849 CCLE Cell Line Gene CNV Profiles 1.0 1.84619 Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 SLR23 CCLE Cell Line Gene Expression Profiles 1.0 1.44659 Dentate gyrus, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11165 ventrolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.834151 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59824 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908659 Sperm flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.619 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44806 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.06362 CUX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7795 p3 portion of the substantia nigra pars compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0105 HGC27 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 POLE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13471 primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05206 r2 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.29421 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Omasum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.772 SLC36A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46821 SF3A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00917 periventricular stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2547 superficial stratum of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48081 cytoplasmic membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.449643 GSE118617,GSE118619_2_v_3_foxp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null precommissural pretectal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02827 DBTRG05MG DepMap CRISPR Gene Dependency 1.0 5.07633 496100348_TCx_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00072 Lysozyme-like protein 4 InterPro Predicted Protein Domain Annotations 1.0 null CABLES1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9927 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05834 STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Hi-5 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.554 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5746-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08723 SP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01998 RB1_KD_GSE50532_660_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null cognitive disorder GWASdb SNP-Disease Associations 1.0 0.152972 GSE119701_0_v_1_phf7_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE111385_2_v_3_tgfbr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P300-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K27me3_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2195_KO_Tnfaip3_SRP103751 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -19.0969 RFX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94713 M14 COSMIC Cell Line Gene Mutation Profiles 1.0 null bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.16217 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF430 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50475 hsa-miR-195 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 CTCF_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nod2_21335489_hek293_lof_human_gpl570_gds4416 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.525885 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54702 medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20394 Sperm head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.043 MIEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40394 BICR31 CCLE Cell Line Gene CNV Profiles -1.0 -1.46806 NDUFA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91832 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.9457 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prelimbic area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27687 posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.986789 Mesenteric lymphadenitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.142 RB1_KD_GSE50532_659_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8585 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.095 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9824 amygdaloid complex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.90068 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Body mass index GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.05229 Cervical adenosquamous carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.41 KAT6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68004 Prostate adenocarcinoma_PRAD_TCGA-J9-A8CN-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null serotonin-activated cation-selective channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.908 ANAPC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15227 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null central subpallium (classic basal ganglia) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02827 JUN JASPAR Predicted Transcription Factor Targets 1.0 null intermediate stratum of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18883 PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.03139 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CK-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HIC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7802 mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null SUZ12 ChEA Transcription Factor Targets 1.0 null subpallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43059 GSE146156_2_v_3_tagap_mouse RummaGEO Gene Perturbation Signatures -1.0 null AR-22383394-PROSTATE-CANCER-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SRRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74395 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.436 internal globus pallidus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral (dentate) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38509 H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056813 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.37146 superficial stratum of DTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88545 mantle zone of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38509 PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-ORKIN_MAX_MAX Rummagene Transcription Factor Associations 2026 1.0 null Postsubiculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22458 Rectum adenocarcinoma_READ_TCGA-AG-3742-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4851 CD79B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90974 GRB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6747 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-ENSEMBL_AR Rummagene Transcription Factor Associations 2026 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null periventricular stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00961 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34783 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null frontal operculum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33675 RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4444 mantle zone of Pal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.22783 CTCF_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.824 JARID2 ChEA Transcription Factor Targets 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Ventilation pneumonitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.725 Digestive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Psmb TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.603 BARX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06207 submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03114 GSE101336_1_v_3_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null nerve GTEx Tissue Gene Expression Profiles -1.0 -1.14207 basal plate of p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00137 HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22141 Brain Lower Grade Glioma_LGG_TCGA-DB-A4XH-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844153 orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.931998 superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48081 8305C CCLE Cell Line Gene Expression Profiles -1.0 -2.03308 Precancerous Conditions CTD Gene-Disease Associations 1.0 1.06442 Anteroventral nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 GSE148066,GSE157787_2_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A54R-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4575 PSN1 CCLE Cell Line Gene CNV Profiles 1.0 1.62705 H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null intergeniculate leaflet Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 mRNA_SFPI1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ASH-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null TestisIntersitial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null TCF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7107 mRNA_MEF2C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GSE207582_2_v_1_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null SW1271 CCLE Cell Line Gene CNV Profiles 1.0 1.63644 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.99696 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08848 muscle GTEx Tissue Gene Expression Profiles -1.0 -0.83076 Varicocele DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.031 soft tissue HPA Tissue Protein Expression Profiles 1.0 0.823441 GSE175787_8_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null GSE219274,GSE219276_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null 496100659_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.77643 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.895355 substantianigra BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.989482 Acute Myeloid Leukemia_LAML_TCGA-AB-2862-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Basolateral amygdalar nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07966 mantle zone of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8 Rummagene Transcription Factor Associations 2026 1.0 null mantle zone of Dg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10328 HPAFII DepMap CRISPR Gene Dependency 1.0 8.11234 all GWASdb SNP-Phenotype Associations 1.0 0.029485 SKNAS CCLE Cell Line Gene CNV Profiles -1.0 -1.50294 CTCF_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NH-12 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.847658 Secretory granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.432 ATXN7L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91451 Adrenocortical carcinoma_ACC_TCGA-OR-A5LC-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.59124 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55563 BEND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79365 SETDB1_KO_GSE40296_7_mouse_brain (telencephalon) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null r2 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07766 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.944915 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null PAX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1181 ventral tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16094 Katanin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.505 amygdaloid complex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.829466 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-ORKIN_E2F4_E2F4 Rummagene Transcription Factor Associations 2026 1.0 null ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.22671 RBP2_deficiency_GDS2731_62_mouse_embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Anteromedial visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19096 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19161 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.971286 GSE148066,GSE157787_2_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.217732 Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.446862 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4482 PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.668843 Contractile vacuole complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.327 ACSL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89805 GSE148066,GSE157787_5_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null extracellular region LOCATE Predicted Protein Localization Annotations 1.0 null Nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46074 Urinary tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TRMT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60689 amygdaloid complex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15078 SW1353 CCLE Cell Line Gene Expression Profiles -1.0 -2.09583 STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2097 ChIP_EZH2_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.6032 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41495 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.839764 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SCA1_Knock-in_GDS1756_231_mouse_Cerebellum tissue - 4 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 mRNA_T_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.09606 DNAJA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83046 Lung adenocarcinoma_LUAD_TCGA-78-8655-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6983-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59653 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2303 Perturb_3454_KO_Ugt8_SRP073495 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.55133 GSE180800,GSE180801_0_v_5_tex10_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lysozyme-like domain InterPro Predicted Protein Domain Annotations 1.0 null nucleus GO Cellular Component Annotations 2025 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of p3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23415 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferior temporal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.864506 PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_38_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null hydrolase activity GO Molecular Function Annotations 2015 1.0 null PC3 CCLE Cell Line Gene CNV Profiles 1.0 1.40926 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.9457 Substantia nigra, reticular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48671 Breast TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Lung adenocarcinoma_LUAD_TCGA-64-1680-01A-02R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.930989 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.891189 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Caudoputamen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78255 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00224 POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE124410_6_v_4_stk40_mouse RummaGEO Gene Perturbation Signatures -1.0 null Acrosomal vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 SMAD3-21741376-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00961 superficial stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78255 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.07065 PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-SYMBOL_AR Rummagene Transcription Factor Associations 2026 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null SLC39A13_Deficiency_GDS3485_570_mouse_Chondrocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Caput epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.55 HMEL CCLE Cell Line Gene Expression Profiles 1.0 1.83028 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34783 hsa-miR-3136-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042768 ROS50 DepMap CRISPR Gene Dependency 1.0 3.69719 psychotic disorder GWASdb SNP-Disease Associations 1.0 0.352461 Micronuclei, Chromosome-Defective CTD Gene-Disease Associations 1.0 1.41613 H3K27me3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NANOG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10087 RCC4 CCLE Cell Line Gene Expression Profiles 1.0 1.44578 GSE184884_2_v_1_gps2_mouse RummaGEO Gene Perturbation Signatures 1.0 null acrosomal vesicle GO Cellular Component Annotations 2025 1.0 null HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3192 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.145242 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47622 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00274 17699763-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null mediodorsal nucleus of thalamus_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5676 Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 Testis BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.31354 GSE148066,GSE157787_0_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE171724_4_v_6_ezh2_mouse RummaGEO Gene Perturbation Signatures -1.0 null JHESOAD1 CCLE Cell Line Gene Expression Profiles 1.0 1.39635 ZNF547 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.0709 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.849527 Lateral dorsal nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38509 CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9183 I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.941203 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE130690,GSE130692_1_v_0_sirt6_mouse RummaGEO Gene Perturbation Signatures 1.0 null TIG3TD CCLE Cell Line Gene Expression Profiles 1.0 1.98336 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5263 PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42791 EWSR1 ChEA Transcription Factor Targets 1.0 null septal nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05265 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.0751 stomach HPA Tissue Protein Expression Profiles 1.0 0.949531 Taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69802 NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998738 HS822T CCLE Cell Line Gene Expression Profiles -1.0 -1.86137 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34783 AR-25329375-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.15788 GSE148066,GSE157787_0_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP Rummagene Transcription Factor Associations 2026 1.0 null GSE195559_0_v_7_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null KYM1 CCLE Cell Line Gene Expression Profiles 1.0 1.63136 ChIP_SUZ12_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null nucleus GO Cellular Component Annotations 2023 1.0 null STAT5A ChEA Transcription Factor Targets 1.0 null mantle zone of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00961 H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Inner acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.486 TestisSeminiferousTubule BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.05412 IRF8-27001747-CHIP-SEQ-BMDM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC12304111-41598_2025_13196_MOESM5_ESM.xlsx-Sheet_1-Table_S4_DEGs_Log2FC_1_and_p_adj_0_05_in_pancreatic_cancer_with_high_versus_low_OVOL1_expression_OVOL1 Rummagene Transcription Factor Associations 2026 1.0 null nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 WAOSEL DepMap CRISPR Gene Dependency 1.0 6.47573 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.901808 GSE136232,GSE136234_0_v_1_zpbp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null TEAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9188 Tripartite attachment complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.082 Lung adenocarcinoma_LUAD_TCGA-64-5778-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00961 mantle zone of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 Midgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.14 JHH1 CCLE Cell Line Gene Expression Profiles 1.0 1.40274 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 JARID1B-DAIN-22020125-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ZNF528 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5357 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4834 biological_process GO Biological Process Annotations 2015 1.0 null JHOS2 CCLE Cell Line Gene CNV Profiles 1.0 2.04155 TBX15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91655 HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.834093 PRKAR1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3285 Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.7043 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05037 Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TestisLeydigCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.15964 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67026 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.053523 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12203 H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.875 Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9083 sublayer 6b of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.22783 GSE138633_2_v_0_bag3_human RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hydrolase activity, acting on glycosyl bonds GO Molecular Function Annotations 2015 1.0 null mantle zone of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05322 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.6318 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Dermatofibroma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.901 CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.53628 SUZ12-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE164483_2_v_0_venetoclax_mouse RummaGEO Drug Perturbation Signatures 1.0 null TMBIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95519 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Leaf disc TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.997 Opisthorchiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.069 anterior pretectal nucleus, dorsal superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78255 UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Liver Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.15223 NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1414 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Bmi-1_KD_GDS2724_102_human_DAOY medulloblastoma cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null r4 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19026 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null LU-134-A COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null 496100458_FWM_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.6438 IGROV1 DepMap CRISPR Gene Dependency 1.0 4.34057 GSE224096_3_v_0_cocaine_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH2172 CCLE Cell Line Gene CNV Profiles 1.0 2.90427 CTCF_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11498 GSE148692,GSE148695_2_v_6_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Infralimbic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66761 pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98164 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848324 H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PHF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97366 nfe2l2_22586274_liver_lof_mouse_gpl4134_gse35124 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.197103 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.035 Seminal plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.143 p2 portion of the substantia nigra pars compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98699 intermediate tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00961 HPBALL CCLE Cell Line Gene CNV Profiles -1.0 -1.3728 REH CCLE Cell Line Gene CNV Profiles -1.0 -1.41747 H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE144231_6_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sc TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.018 Lung adenocarcinoma_LUAD_TCGA-97-A4M6-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CALR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90694 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null AR-22383394-PROSTATE_CANCER-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null navicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7714 ECC12 CCLE Cell Line Gene Expression Profiles -1.0 -2.07019 TCF4 ChEA Transcription Factor Targets 1.0 null TMEM205 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98597 HOMEZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11931 liminal periaqueductal gray of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34506 Supramammillary nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08675 15273739-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null testis HPA Tissue Protein Expression Profiles 1.0 0.949531 periventricular stratum of Dg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 SOX9 ChEA Transcription Factor Targets 1.0 null Cortical granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.526 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13029 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GATA2-19941826-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE129186,GSE129223_0_v_1_aicda_mouse RummaGEO Gene Perturbation Signatures 1.0 null SUZ12-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TMEM120A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11062 CTCF-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82505 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE232631_0_v_2_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Taenia tecta, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90692 NCIH2291 DepMap CRISPR Gene Dependency 1.0 2.07676 TRIM33_KD_GDS4071_449_human_HMEC-TR mammary epithelial cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null temporal pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0201 striatum_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.987785 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 DNAJC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90933 SW480 CCLE Cell Line Gene Expression Profiles 1.0 1.34959 Liver TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 496100493_TCx_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.12445 PK45H CCLE Cell Line Gene Expression Profiles 1.0 1.52829 GSE117042_0_v_3_tunicamycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null DU4475 DepMap CRISPR Gene Dependency 1.0 2.40722 hsa-miR-324-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 CNR_KO_GDS2820_636_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BT474 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.00285 PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-GeneExpression_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26614 NCI-H1651 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.2817 semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.624658 Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69567 hsa-miR-4796-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 CHDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71583 BHLHE23 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6723 KMS-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.997579 DYNLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49745 Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.231 pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.142657 Prostate adenocarcinoma_PRAD_TCGA-HC-8261-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Reasoning DisGeNET Gene-Phenotype Associations 1.0 null Infralimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89818 intermediate stratum of Pal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.53059 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8904 GSE244072_10_v_9_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null thalamic (p2) zona limitans domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38509 GSE206984_1_v_0_bortezomib_human RummaGEO Drug Perturbation Signatures 1.0 null PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.997579 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22079 primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15503 superficial stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00961 Postsubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SW1417 CCLE Cell Line Gene CNV Profiles 1.0 1.39916 SOX9-24532713-HFSC-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Spermatozoon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.408 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JARID2-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null TestisGermCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55362 CLPP_KO_GSE40207_378_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null prethalamic (p3) zona limitans domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05322 Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.00794 HT-144 COSMIC Cell Line Gene Mutation Profiles 1.0 null WM3772F DepMap CRISPR Gene Dependency 1.0 2.97422 VAC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53464 estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bed nucleus of the stria terminalis, mediocentral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.9457 Alzheimer Disease DisGeNET Gene-Disease Associations 1.0 null PEO4 DepMap CRISPR Gene Dependency 1.0 4.64567 PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP Rummagene Transcription Factor Associations 2026 1.0 null AML193 DepMap CRISPR Gene Dependency 1.0 2.65789 RCCFG2 DepMap CRISPR Gene Dependency 1.0 3.21878 SP110 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37212 Glycoside hydrolase, family 22 InterPro Predicted Protein Domain Annotations 1.0 null Ooplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.111 GSE239747_2_v_3_lrp6_mouse RummaGEO Gene Perturbation Signatures -1.0 null CAL33 CCLE Cell Line Gene CNV Profiles -1.0 -1.7943 Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9556 CAL27 CCLE Cell Line Gene CNV Profiles -1.0 -1.39158 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null mantle zone of r2BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70507 dorsolateral part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00961 mantle zone of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60989 CCLFPEDS0008T DepMap CRISPR Gene Dependency 1.0 2.59 SRSF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06456 periventricular stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03114 Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29609 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3006 orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.13305 temporal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02536 Ebolavirus(ZEBOV)_3day_Liver_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.46671 PF382 DepMap CRISPR Gene Dependency 1.0 3.19938 GSE154074_2_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null lateral part of alar p2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78255 CTCF_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ventral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48081 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2025 1.0 null plexiform layer of TuStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22458 levodopa_rattus norvegicus_gpl4135_gse43375 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0299 temporal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33935 disease GWASdb SNP-Disease Associations 1.0 0.026074 Primary somatosensory area, upper limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03411 SF172 CCLE Cell Line Gene Expression Profiles 1.0 2.23582 COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05037 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 496100354_PCx_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.05941 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.02513 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-7268-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1385 CCLE Cell Line Gene CNV Profiles -1.0 -1.40582 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.645 BAG3 Pathway Commons Protein-Protein Interactions 1.0 null GSE148066,GSE157787_5_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null A1BG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85948 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TMEM42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14858 B3GALT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22986 D341Med DepMap CRISPR Gene Dependency 1.0 2.87445 PLAGL2_deficiency_GDS3010_139_mouse_embryonic small intestine GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6374 intuition GAD Gene-Disease Associations 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null HS746T CCLE Cell Line Gene Expression Profiles -1.0 -2.16559 PMC6617737-13059_2019_1747_MOESM1_ESM.xlsx-Table_s7_szDMP_OLIG2-Unnamed_23_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.71517 HCC1419 COSMIC Cell Line Gene Mutation Profiles 1.0 null HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70685 Cestode TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.407 superior colliculus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.89352 Metaplasia CTD Gene-Disease Associations 1.0 1.04314 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.998876 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.1681 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.0351 Anteromedial nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.22783 intracellular part GO Cellular Component Annotations 2015 1.0 null 496100368_PCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18786 nucleus of the stria terminalis, medial division, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22458 Superior olivary complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28125 NCI-H2803 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924652 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 mRNA_EOMES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.4545 GSE139975_3_v_0_rnf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null TTT complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.934 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JD-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rosette leaf TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.319 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21165 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.999598 Pancreas TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 r1 part of superior vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03114 TADA2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68617 CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OXCT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67987 CREB3L4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.596 Infertility, Female CTD Gene-Disease Associations 1.0 1.11046 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7385-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1792 UBA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3408 MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.815312 MIST1_KO_GDS1731_758_mouse_Pancreas GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SKNBE2 CCLE Cell Line Gene CNV Profiles -1.0 -1.36175 GSE241036_4_v_2_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.7499 Bmi1_Deficiency_GDS4816_323_mouse_Primary lung cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCOA2_KO_GDS5087_24_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-544 TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 Tongue epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.771 Cilium COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 basal plate of p2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36934 9+2 motile cilium GO Cellular Component Annotations 2023 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.525 Taenia tecta, ventral part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32093 lateral part of r3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10723 Striatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07751 HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8804 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3821 KP2 DepMap CRISPR Gene Dependency 1.0 2.97145 BICR31 DepMap CRISPR Gene Dependency 1.0 2.30421 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A6-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.868311 posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.948509 GSE191105_0_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null L428 DepMap CRISPR Gene Dependency 1.0 2.44229 Substantia nigra, compact part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63048 Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.8488 AR ChEA Transcription Factor Targets 1.0 null ventral lateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.27942 NCIH1092 CCLE Cell Line Gene Expression Profiles -1.0 -1.70553 GSE184210_0_v_1_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null MAFA MotifMap Predicted Transcription Factor Targets 1.0 null superficial stratum of m1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00137 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72977 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF ChEA Transcription Factor Targets 1.0 null H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.531879 bed nucleus of the stria terminalis, medioseptal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03114 posterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.7998 CLPP_KO_GDS4791_374_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_1818_KO_Adam17_SRP394864 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_MTF2_20144788 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42849 HCC1395 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.875466 UO31 CCLE Cell Line Gene CNV Profiles 1.0 1.43421 disease of mental health GWASdb SNP-Disease Associations 1.0 0.060907 GSE197850_4_v_0_glucagon_human RummaGEO Drug Perturbation Signatures 1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 mRNA_NRIP1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.267 GSE196104,GSE196106_2_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCOA2_KO_GSE41558_19_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Cauda epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.938 Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 trochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07698 p2 portion of the parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03115 vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.331719 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3441 Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.9886 GSE223008_7_v_1_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6332 MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.55933 Peritrophic membrane TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.342 SLR26 CCLE Cell Line Gene Expression Profiles 1.0 1.52675 Intestinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.525 HDAC1 ENCODE Transcription Factor Targets 1.0 null Malpighian tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.071 TSHZ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83656 H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsal peduncular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17157 Anterior midgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.674 CDK17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91339 GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null gallbladder HPA Tissue Protein Expression Profiles 1.0 0.949531 9+2 motile cilium COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11498 medial orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.949532 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14163 Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA2-19941826-K562-human ChEA Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taste bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.832 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5605 Anterior group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2974 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.2478 PMC4424395__F6 PFOCR Pathway Figure Associations 2024 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042048 ZBTB7C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0034 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.997579 GSU DepMap CRISPR Gene Dependency 1.0 3.12739 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44636 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13029 EZH2 ENCODE Transcription Factor Targets 1.0 null GSE226091,GSE226092_0_v_4_sall1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34185 superficial stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38056 GSE148066,GSE157787_5_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TOV21G CCLE Cell Line Gene Expression Profiles -1.0 -1.59423 ABI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82867 CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SARM_KO_GDS4842_411_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F6_E2F6 Rummagene Transcription Factor Associations 2026 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null DOT1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55636 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.988165 GSE148066,GSE157787_2_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Primary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.376 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57165 HUPT4 CCLE Cell Line Gene CNV Profiles 1.0 2.10988 TFAP2A JASPAR Predicted Transcription Factor Targets 1.0 null GSE221327_1_v_9_clpp_human RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5772-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gonocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.931 CJUN-26792858-CHIP-SEQ-BT549-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ARF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72964 Hemolymph TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.203 A673 CCLE Cell Line Gene CNV Profiles -1.0 -1.67619 CDX2-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Primary somatosensory area, unassigned, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16389 496100573_HIP_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.33028 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Postsubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07751 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.91739 CAL120 CCLE Cell Line Gene CNV Profiles -1.0 -1.59209 H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lysozyme activity GO Molecular Function Annotations 2015 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6157-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Posterior parietal association areas, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19096 posteroventral (inferior) parietal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.85333 ChIP_SUZ12_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null pontine raphe nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.894405 18614019-TableS4c GeneSigDB Published Gene Signatures 1.0 null GSE223008_7_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE207582_4_v_3_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null NCIH2029 CCLE Cell Line Gene CNV Profiles 1.0 1.57916 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.909885 MTF2-20144788-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46557 Prostate adenocarcinoma_PRAD_TCGA-G9-6370-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-VN-1203-2004(H5N1)_Day7-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.44658 YT COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100306_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.17951 IGF2BP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94152 GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1573 Striatum dorsal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78255 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null INSM1_KO_GDS5066_472_mouse_pituitary gland GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Nucleus of the lateral lemniscus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9136 Lateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16094 Lung Diseases CTD Gene-Disease Associations 1.0 1.1403 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63115 Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1113 HSC4 DepMap CRISPR Gene Dependency 1.0 2.10306 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25833 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH838 CCLE Cell Line Gene CNV Profiles 1.0 1.34044 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26417 SAP30 ENCODE Transcription Factor Targets 1.0 null GSE154074_1_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null TWSG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50776 organelle GO Cellular Component Annotations 2015 1.0 null GSE223008_5_v_3_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE195559_0_v_5_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null Chromatoid body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.581 mantle zone of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15201 GSE166169_2_v_3_elp3_mouse RummaGEO Gene Perturbation Signatures -1.0 null pyramidal layer of taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10893 Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE224556,GSE224557_6_v_1_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null parolfactory gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16262 PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null anterior digastric muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39926 lateral part of r2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70555 mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06148 Perturb_2002_KO_Irf8_SRP265130 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE224096_2_v_0_cocaine_human RummaGEO Drug Perturbation Signatures 1.0 null CREBBP ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24724 Brain Lower Grade Glioma_LGG_TCGA-QH-A6XC-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE219274,GSE219276_3_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.057504 PHGDH_KO_GDS2874_125_mouse_embryonic head tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9658 TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.753 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895268 anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.847658 U266B1 CCLE Cell Line Gene Expression Profiles 1.0 1.48004 MTCH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39511 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUZ12-16625203-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 496100612_HIP_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.67984 Infralimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14338 GSE179880_1_v_5_e2f4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Taenia tecta, dorsal part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42624 PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-ATF3_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054423 CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5550-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.931264 GSE176008_8_v_5_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null HCC2185 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.815712 GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null periventricular stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34656 Ventral posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68909 GALR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85553 Fibrillation DisGeNET Gene-Disease Associations 1.0 null ADAMTS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61723 SP3_Deficiency_GDS3058_610_mouse_Embryonic heart (day 12.5 C57Bl/6) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RUNX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29435 NCIH358 DepMap CRISPR Gene Dependency 1.0 3.92819 UACC893 DepMap CRISPR Gene Dependency 1.0 3.92498 MFSD2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93614 GSE88819_1_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Secretory granule COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null EBAG9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73732 NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.988541 mantle zone of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05322 Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.19 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null mantle zone of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11064 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTF2-20144788-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 cingulate gyrus, frontal part, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.877189 ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.09 cell part GO Cellular Component Annotations 2015 1.0 null OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.983392 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.944915 Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN74 CCLE Cell Line Gene CNV Profiles -1.0 -2.04582 RAB3A_KO_GDS2482_705_mouse_Cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE195514_0_v_1_stk25_human RummaGEO Gene Perturbation Signatures -1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5508 GSE148066,GSE157787_11_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.873 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.944915 external globus pallidum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.53059 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.67686 Extracellular region COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 496100305_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.09123 Taenia tecta, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.24376 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.062177 striatum (corpus striatum) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19096 NCIH2066 CCLE Cell Line Gene CNV Profiles -1.0 -1.73556 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.029518 AIF1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74301 Taenia tecta, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67688 mantle zone of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19096 Seminiferous epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.806 NCIH716 DepMap CRISPR Gene Dependency 1.0 2.32616 claustrum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.85066 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.56375 Extracellular space COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Infralimbic area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52776 PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null Extrinsic allergic alveolitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.031 kdm5a_17320163_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse6945 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.021304 HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848324 A1207 CCLE Cell Line Gene Expression Profiles 1.0 1.45588 CREBBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF282 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.6359 Acrosomal matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.117 GSE184884_4_v_1_gps2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5565 ChIP_H3K9me3_19884255_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.080053 GSE130081,GSE130082_0_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE148066,GSE157787_8_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null submammillothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0953 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 p1 part of the substantia nigra compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43925 Thalamus, polymodal association cortex related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48081 POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null alar plate of p2 (alar thalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33979 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.525 cSARS Bat SRBD_36Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.34473 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF274 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6798 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.81439 superior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15576 defense response to bacterium GO Biological Process Annotations 2025 1.0 null mantle zone of p3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00302 short insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.56538 Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF121 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55748 CTCF_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMC18 CCLE Cell Line Gene Expression Profiles 1.0 1.54928 19658189-TableS3 GeneSigDB Published Gene Signatures 1.0 null SARM_KO_GDS4842_412_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null H2BC21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77795 DMS-114 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null p1 part of the substantia nigra reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13467 H2AFZ ENCODE Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22983 SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924652 CTCF_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 17910759-TableS5 GeneSigDB Published Gene Signatures 1.0 null G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04948 sperm flagellum GO Cellular Component Annotations 2025 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE190186,GSE190188_0_v_5_apoe_mouse RummaGEO Gene Perturbation Signatures 1.0 null dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BICR18 CCLE Cell Line Gene Expression Profiles -1.0 -1.64203 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AP3D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65996 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18069 primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0844 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.436438 H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null plastid-encoded plastid RNA polymerase complex A COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.556 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.43184 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844153 superior frontal gyrus, right, medial bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04871 184B5 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.1494 amygdaloid complex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0352 NB17 DepMap CRISPR Gene Dependency 1.0 2.78506 CFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56772 dorsal tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68909 dorsolateral part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03114 Spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.462 SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.0264 Geniculate group, dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.57098 salivary gland GTEx Tissue Gene Expression Profiles 1.0 0.827276 psychotic disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19753 NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49845 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51527 Prelimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18179 periventricular stratum of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.53059 IOMMLEE CCLE Cell Line Gene Expression Profiles 1.0 2.25661 layer 6 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03114 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null suprachiasmatic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10328 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R3-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.45986 GSE130081,GSE130082_4_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null superficial stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15691 G292CLONEA141B1 DepMap CRISPR Gene Dependency 1.0 3.15699 hydrolase activity, hydrolyzing o-glycosyl compounds GO Molecular Function Annotations 2015 1.0 null CHCHD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69447 Glycoside hydrolase, family 22, conserved site InterPro Predicted Protein Domain Annotations 1.0 null CEBPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76252 GSE223008_5_v_1_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null TMED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62243 HS729 CCLE Cell Line Gene CNV Profiles 1.0 1.93097 MRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29177 GSE86507,GSE86509_3_v_8_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null p3 portion of the substantia nigra pars reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38019 HDAC6 ENCODE Transcription Factor Targets 1.0 null JEG3 DepMap CRISPR Gene Dependency 1.0 2.91402 NCIH838 DepMap CRISPR Gene Dependency 1.0 4.15419 sublayer 6a of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07665 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Response to antipsychotic treatment in schizophrenia (reasoning) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.6 r1 part of vestibular sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07751 extracellular region LOCATE Curated Protein Localization Annotations 1.0 null 639V CCLE Cell Line Gene CNV Profiles 1.0 1.45478 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.046029 H3K9me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.190281 GSE212487,GSE212488_0_v_1_gata4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE148066,GSE157787_9_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PRKX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28497 MDAMB436 CCLE Cell Line Gene Expression Profiles -1.0 -1.81604 A4/FUK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70685 HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Hemocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.26 plastid-encoded plastid RNA polymerase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.518 GSE203655_0_v_1_stat1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PEG10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40482 NCIH1436 CCLE Cell Line Gene CNV Profiles -1.0 -1.48573 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ILVBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04153 GSE148066,GSE157787_11_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMARCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29241 mantle zone of DTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68909 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68272 Prostate adenocarcinoma_PRAD_TCGA-HC-A6HY-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.399114 PMC4521181-oncsis201520x8.pdf-29-TBX18_TBX18 Rummagene Transcription Factor Associations 2026 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null intermediate stratum of DTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05322 KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.32389 HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE226316_0_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5 Anterior cingulate area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23053 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13029 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.666 CEBPB JASPAR Predicted Transcription Factor Targets 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33506 YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null intermediate stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 KMM1 CCLE Cell Line Gene CNV Profiles 1.0 2.14904 GSE118617,GSE118619_0_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null E2F3_KD_GDS4094_448_mouse_Mammary tumors (Myc-induced) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ChIP_H3K27me3_17603471_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PIK3CA_mutant_27_GDS4053 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.64109 Perturb_1948_KO_Prkcd_SRP386893 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.5821 OCILY3 CCLE Cell Line Gene CNV Profiles 1.0 1.52423 STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY ChEA Transcription Factor Targets 2022 1.0 null Antipodal site COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.708 dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07136 Cotton fibre TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.566 Declive (VI), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38509 SRC-2_Deficiency_GDS5087_270_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7425 GGA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13346 Cytoplasmic vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.00033 ERI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15483 PARD6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02729 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STYX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78211 intermediate stratum of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00961 inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.73305 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20141 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07774 GATA2-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null claustrum, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.4993 ZNF419 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47005 temporal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2971 SMAD4-21741376-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ICC3 DepMap CRISPR Gene Dependency 1.0 2.23478 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08572 Sarcoma_SARC_TCGA-DX-A3M1-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCARF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13478 WDR77 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8158 FBN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53339 SNU1214 CCLE Cell Line Gene CNV Profiles -1.0 -1.53692 posteroventral (inferior) parietal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.923654 GSE148066,GSE157787_8_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.06331 KYSE520 CCLE Cell Line Gene Expression Profiles 1.0 1.37078 Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.4256 PANX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10941 Plasma membrane bounded cell projection COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BC3C CCLE Cell Line Gene Expression Profiles -1.0 -1.72503 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6824-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decitabine_homo sapiens_gpl570_gse30985 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null catalytic activity GO Molecular Function Annotations 2015 1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ARX_KO_GSE12609_3_mouse_brain (subpallium, Pou3f-expressing cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44479 superficial stratum of r2BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.29519 orbital frontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.953827 amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.77629 KDM5A ENCODE Transcription Factor Targets 1.0 null STAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.281 CELF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08673 KP-N-RT-BM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51527 GSE148066,GSE157787_9_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6979-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferior temporal gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.852525 NCIH2087 CCLE Cell Line Gene Expression Profiles -1.0 -3.47125 KINGS1 DepMap CRISPR Gene Dependency 1.0 5.46476 FZD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53015 INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null thalamic tegmentum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36934 Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2778 HEC1B CCLE Cell Line Gene CNV Profiles 1.0 2.2476 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7236-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE232631_5_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11587 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 SMAD3-22036565-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.160624 mantle zone of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02362 Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45201 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS JASPAR Predicted Transcription Factor Targets 1.0 null Thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54136 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCAN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14498 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57165 Egg white TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.433 CAOV4 DepMap CRISPR Gene Dependency 1.0 3.1937 Labial palp TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.848 KLF5_KO_GDS3509_553_mouse_ES cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47622 CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GFI1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92993 CLPP_KO_GSE40207_388_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K9me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null AML193 CCLE Cell Line Gene CNV Profiles 1.0 1.43605 hsa-miR-4680-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null TCF7 ChEA Transcription Factor Targets 1.0 null ANKRD13D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33042 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.997579 GATA3_01_347 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.08554 mRNA_ATF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null defense response to bacterium GO Biological Process Annotations 2023 1.0 null Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.131 primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01069 mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98044 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NOXO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89008 lateral part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 intermediate stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73752 superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98164 POGZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97315 496100661_PCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07253 Posterior midgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.541 periventricular stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03114 BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.944546 Thorax TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 UACC893 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.596287 HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.963 H3K9me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.825249 GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4774 SLC25A36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25371 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAB34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54239 r3 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72532 NCIH2347 CCLE Cell Line Gene CNV Profiles 1.0 1.40579 A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^3_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.11116 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.832003 GSE232631_4_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Secondary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.392 Trunk TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null COLO205 CCLE Cell Line Gene Expression Profiles 1.0 1.81451 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Submedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05322 RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23815 Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF214 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2047 CAPAN1 CCLE Cell Line Gene CNV Profiles 1.0 2.47492 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 GSE114992,GSE114993_9_v_2_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null ENHO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81647 Itch intensity from mosquito bite adjusted by bite size GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.6 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05037 TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5802 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.719113 Hyperplasia CTD Gene-Disease Associations 1.0 1.55182 nucleus GO Cellular Component Annotations 2015 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CREM JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8775 posterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.897007 Cerebellar cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13051 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.30413 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63115 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4778-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.205675 GSE221020,GSE221023_2_v_1_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.43169 RKO CCLE Cell Line Gene Expression Profiles 1.0 1.81877 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35569 JAR DepMap CRISPR Gene Dependency 1.0 2.24813 internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.717882 Sarcoma_SARC_TCGA-PC-A5DL-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null no abnormal phenotype detected MGI Mouse Phenotype Associations 2023 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33506 Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null schizophrenia GWASdb SNP-Disease Associations 1.0 1.19386 TCF7-22412390-EML-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB361 DepMap CRISPR Gene Dependency 1.0 6.33737 TP53_01_68 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.60723 TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1769 Septohippocampal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54726 layer 6 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10328 superficial stratum of p2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02583 RCM1 DepMap CRISPR Gene Dependency 1.0 10.7019 Male infertility due to globozoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.321 GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2562 MAPKAPK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26128 Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF106 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84613 SMAD4-21741376-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-4439 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-ORKIN_CTCF_CTCF Rummagene Transcription Factor Associations 2026 1.0 null Primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.517 Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null substantia nigra reticulata, isthmic part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15798 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.66 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.19699 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.36698 QKI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83771 GSE148066,GSE157787_2_v_1_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6696 primary motor-sensory cortex (samples)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.931998 MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null YY1_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null intermediate stratum of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07751 gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.894346 HUP-T4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924652 temporal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30278 ventromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2974 OE19 CCLE Cell Line Gene Expression Profiles 1.0 1.97288 schizophrenia GWASdb SNP-Phenotype Associations 1.0 1.04365 Kidney TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MYOG_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYOG ENCODE Transcription Factor Targets 1.0 null NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895268 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null extracellular region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Central medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2974 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.29774 EED-16625203-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null 496100324_FWM_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.99464 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15278 PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24 Rummagene Transcription Factor Associations 2026 1.0 null GSE124410_2_v_4_stk40_mouse RummaGEO Gene Perturbation Signatures -1.0 null CLPP_KO_GSE40207_392_mouse_Testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null EJM DepMap CRISPR Gene Dependency 1.0 2.20247 SMAD3-21741376-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null Necrosis CTD Gene-Disease Associations 1.0 1.26825 SMAD3 ChEA Transcription Factor Targets 1.0 null GPN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11185 PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848324 Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22458 dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.842762 Bacteriocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.457 A172 CCLE Cell Line Gene Expression Profiles -1.0 -2.5484 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FZD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87386 KNS81 CCLE Cell Line Gene Expression Profiles -1.0 -1.51009 frontal operculum, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.976077 ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5642 HINFP JASPAR Predicted Transcription Factor Targets 1.0 null NCIH1694 CCLE Cell Line Gene CNV Profiles -1.0 -1.88555 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 CPCN CCLE Cell Line Gene CNV Profiles -1.0 -1.52842 ChIP_JARID2_20075857 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null UBE2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3684 Dried cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.528 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.831397 Cerebral nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10328 SEC22C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14506 Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Contractile vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.442 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053998 CCDC134 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91011 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8423 GSE223008_7_v_3_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE145990_1_v_0_ibrutinib_human RummaGEO Drug Perturbation Signatures -1.0 null klf5_18983969_embryonic_stem_cell_lof_mouse_gpl1261_gds3509 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.105764 COV318 CCLE Cell Line Gene Expression Profiles 1.0 1.62585 SLR24 CCLE Cell Line Gene Expression Profiles 1.0 2.65238 hsa-miR-299-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.248923 9+2 motile cilium GO Cellular Component Annotations 2025 1.0 null farmer's lung DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.233 SUZ12-18974828-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE184884_7_v_1_gps2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Exoskeleton TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.867 DMD_Deficiency_GDS2996_613_mouse_Cardiac muscles from 8-week (mdx animals) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7505 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23011 Connective tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05052 POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.323144 HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908659 RNF2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895268 SNU119 CCLE Cell Line Gene Expression Profiles -1.0 -1.70233 Purpura fulminans DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 layer 1 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09703 ILF2_02_70 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.02237 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3 Axonemal dynein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.726 SCMH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12993 GSE191174_0_v_1_ccdc92_mouse RummaGEO Gene Perturbation Signatures -1.0 null diagonal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10328 mRNA_RHOX6_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Prostate adenocarcinoma_PRAD_TCGA-2A-A8W1-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF792 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60296 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q3-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE148066,GSE157787_8_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null layer 6 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02886 DMS53 CCLE Cell Line Gene CNV Profiles -1.0 -2.04699 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5041 GSE223008_5_v_12_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48081 Reticular nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78255 GOLGA6L9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26668 SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68747 Vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 NCIH1155 CCLE Cell Line Gene Expression Profiles -1.0 -1.50042 pallidum (globus pallidus complex) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.22783 prethalamic tegmentum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00169 Dentate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19096 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.992989 TEAD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8759 SUPT7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65541 Lung adenocarcinoma_LUAD_TCGA-75-5125-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral amygdaloid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25968 striatum_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.55349 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHCHD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77288 r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23706 Glycoside hydrolase, family 22, lysozyme InterPro Predicted Protein Domain Annotations 1.0 null mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.839764 JUND JASPAR Predicted Transcription Factor Targets 1.0 null LPS510 DepMap CRISPR Gene Dependency 1.0 7.6059 RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2235 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.062463 substantia nigra reticulata, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34842 Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.525 GSE122711_2_v_3_mpc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TRAPPC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34575 CEBPB-20513432-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.79108 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GA10 CCLE Cell Line Gene Expression Profiles 1.0 3.12105 KDM4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7052 cytoplasmic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.445275 PMC4424395__F6 PFOCR Pathway Figure Associations 2023 1.0 null mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.09105 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5853 T47D CCLE Cell Line Gene CNV Profiles 1.0 1.82734 p2 portion of the substantia nigra pars reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.23084 Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2998-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral posterolateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78255 Excretory gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Leukemia, Acute Megakaryocytic_Megakaryocyte_GSE2433 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.37584 ventrolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.60893 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Prelimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43967 21205295-TableS1 GeneSigDB Published Gene Signatures 1.0 null JARID2-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null DIFI DepMap CRISPR Gene Dependency 1.0 3.25626 Intuition dbGAP Gene-Trait Associations 1.0 0.50084 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.832003 liminal part of r3 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11064 superficial stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10893 RNF2 ENCODE Transcription Factor Targets 1.0 null HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8599 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9816 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.25581 SUZ12-18692474-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null secretory granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.595593 Field CA1, stratum pyramidale Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05322 H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null intracellular organelle GO Cellular Component Annotations 2015 1.0 null Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Fat body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.325 Ezh2_deficiency_GDS2717_141_mouse_lymph node T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BTBD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42798 PMC3117129-mp2010119x5.xls-CRS_Amg-Unnamed_5_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null icSARA deltaORF6_60Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.54448 Cerebellum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22458 Neuronal ceroid lipofuscinosis 8 northern epilepsy variant DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.425 ventral entopeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32206 ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2213 GSE144231_2_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100414_TCx_probable Alzheimer's disease_no TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.61442 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00303 Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDQP1 CCLE Cell Line Gene Expression Profiles -1.0 -1.87895 metabolic process GO Biological Process Annotations 2015 1.0 null Cell projection COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.856875 POLR2A ENCODE Transcription Factor Targets 1.0 null spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.608527 prerubral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35446 H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null LN443 CCLE Cell Line Gene Expression Profiles 1.0 1.84796 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18181 Nrf2_deficiency_GDS3406_156_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE198380_0_v_1_phgdh_human RummaGEO Gene Perturbation Signatures -1.0 null Manchette COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.03 superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06285 mRNA_CBX8_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Urinary system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Anteromedial nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68909 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09291 MPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20856 RARB-27405468-CHIP-SEQ-BRAIN-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Spermatogenic failure 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.322 CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null p3 portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25072 SOX9-24532713-HFSC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.9457 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844153 H3K27me3_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH2030 DepMap CRISPR Gene Dependency 1.0 2.95415 CTNNAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45041 Weight Loss CTD Gene-Disease Associations 1.0 1.04794 Motile cilium COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 496100553_TCx_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.0754 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5698 PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9677 mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.91894 short insular gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.56921 PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sperm annulus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.138 E2A MotifMap Predicted Transcription Factor Targets 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22983 GSE129293_0_v_1_chd4_human RummaGEO Gene Perturbation Signatures 1.0 null IPO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82304 anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06215 laterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00961 DPP3_OE_GDS2653_650_human_IMR-32 neuroblastoma cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null orbital frontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.98777 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78K-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IGR1 DepMap CRISPR Gene Dependency 1.0 3.83848 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE8 CCLE Cell Line Gene Expression Profiles -1.0 -1.48256 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.21402 JcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00961 long insular gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.865826 tegmental field of p3 (Forel's field) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25944 RAD21 ENCODE Transcription Factor Targets 1.0 null dorsal peduncular cortex, periventricular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2547 LHX1_NULL MUTATION - Ablation_GDS1748_748_mouse_Embryonic kidneys (from day E14.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3551 ChIP_K27me3_17603471_mouseMEF ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HS-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14853 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-513b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 ZNF619 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05471 lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.89877 Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE70499_5_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CLDND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9804 TCF7-22412390-EML-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE184210_0_v_2_glucagon_mouse RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRC-2_KO_GDS5087_485_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SNU1214 CCLE Cell Line Gene Expression Profiles -1.0 -1.73056 Liver Neoplasms CTD Gene-Disease Associations 1.0 1.11606 H3K27me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferior frontal gyrus, opercular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6279 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VN-A88O-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-A491-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5779 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null ZKSCAN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52683 Lung adenocarcinoma_LUAD_TCGA-50-5942-01A-21R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Hypertrophy CTD Gene-Disease Associations 1.0 1.21501 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6868 Field CA1, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25968 EWS-FLI1-20517297-SK-N-MC-HUMAN ChEA Transcription Factor Targets 2022 1.0 null schizophrenia DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.893038 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3467 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.927057 Intrinsic component of synaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.874 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02771 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2762 Flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.966 NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4266 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.067759 C8orf76 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46988 NCI-H1437 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OTX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7384 intermediate stratum of p2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06891 POLR2A_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD4 ChEA Transcription Factor Targets 1.0 null JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5281 PDHX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02395 H3K9me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Night sleep phenotypes GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.569897 r3 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38019 TDRD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8689 pretectum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03114 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.944546 testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.924194 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.58574 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042379 Crystalline style TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.191 superficial stratum of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72388 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0738 Lung adenocarcinoma_LUAD_TCGA-44-3398-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054421 TOR4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69423 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null liminal part of r4 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02362 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.36187 GATA2 ChEA Transcription Factor Targets 1.0 null