association	dataset	threshold value	standardized value
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AC-36-TL21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.742974
BRD-A34842997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28609
EE-01-FB85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.449844
VD-08-TC47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.585927
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
EC-01-PH79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243442
GSE197948_2_v_0_atp7b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.610813
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.40319
GSE230174_0_v_1_dagla_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A96537953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45209
JF-62-LU77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.582446
BRD-K25013674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10455
MA-43-MR37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241861
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.742658
Major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.722185
BD-36-VB52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412606
AC-37-OZ52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.69417
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.34294
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Upstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24549321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65892
AA-58-FJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22469
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50524
CC-18-YW57_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379232
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endomembrane system	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
BRD-K90655269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32764
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.59033
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-52-JS03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27108
DE-30-UR76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.842876
LD-69-ZV56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363085
PMC10079833-41467_2023_37542_MOESM11_ESM.xlsx-Sheet1-Supplementary_Data_10_Significantly_differentially_expressed_genes_identified_in_IGF2BP1-KD_cells_compared_to_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249891
TB-06-VB30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.502944
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3636
DA-27-BW20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400377
CTDSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88443
POLR2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27915
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.87075
CC-09-YG11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.687697
BRD-K79318959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27289
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10462
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.93107
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
BRD-K60839995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14384
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18121
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6633
BRD-K04366109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40011
CACNG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50749
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307481
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.800038
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.3408
BC-01-JL64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.540209
BRD-K22418614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6188
MA-31-VM30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.876509
TE-15-RO34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.968366
BRD-K50045741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02661
LF-94-HB11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.498023
AC-43-ZC52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.885485
JC-63-DO70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22156
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2272
AA-19-EX72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212048
TC-95-IR96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38477
BB-42-FF52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.934941
BF-22-EP86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320859
DA-33-CX68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.814807
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CC-68-YZ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.736722
BRD-A20208638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49774
JF-30-FW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.650806
GSE232944_1_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
a24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.57
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165122_0_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AC-71-YF45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477045
PMC7618435-EMS211310-supplement-Table_S1.xlsx-C1-MUC5AC_ASCL1_progenitor_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
ZB-33-MZ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.516906
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217585
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.60867
BRD-K53544328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37011
Muscular dystrophy-dystroglycanopathy type B5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A94885304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.167
BB-86-BE39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201256
QE-18-WG07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02816
DF-92-CF17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.916976
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30675
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58298
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05338
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.523845
BRD-K10058823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66962
RD-50-EO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.482494
BRD-K47238978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5391
GA-77-MH38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.540841
BB-74-RX30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226168
DA-07-LL18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408932
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24942
BRD-K68314790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39565
Extrachromosomal circular DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
ZB-16-BR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368586
BRD-K98810653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43253
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5169
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27299
BRD-K61168922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55007
DF-00-BU08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.49769
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14936
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CB-46-FO63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23217
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HD-99-BT62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241506
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NB-12-ZK38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02792
JE-22-JR20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.41736
LD-67-CX31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24695
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.31345
TF-04-RX73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.657803
PMC9391581-mmc5.xlsx-WT_KLF4_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BA-26-GI09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357684
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15039
BRD-K35879814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1957
BRD-K34117117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59394
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.64173
CD-20-MH57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200843
496100443_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46085
SC-72-YW56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215783
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17076
AE-22-QI24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293772
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33791
BRD-K20661169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02317
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45431
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AE-38-LX10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.478147
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.700322
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8763
AA-94-TU18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4318
MLL1/2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
AD-86-OB87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.4046
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8981
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7071
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Hip circumference adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
ZNF701	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63261
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HA-22-CY42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.618933
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339409
RZZ complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
WC-82-YS26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342954
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
HE-10-QN66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623777
BB-87-SF89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553147
Joint mobility (Beighton score)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.12218
DB-56-XL71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51875
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230406
GA-09-TM90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277661
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZE-45-CG69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226378
TF-29-QU48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.555161
ZE-14-BN99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303675
GSE166536_0_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K01605333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48071
BRD-K35852282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25545
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
Muscular dystrophy-dystroglycanopathy type B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
EB-82-HZ30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.651015
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BB-86-BE39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332773
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BE-31-XV38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.611884
NQO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80167
CB-55-AK76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.9283
GE-40-GQ38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.835638
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215253
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20394
KDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19603
CENPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62546
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484275
BRD-K04628654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08313
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0552
BRD-K08409548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75413
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78439758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14312
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411107
BA-92-YC70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.744509
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71866
Buphthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
BE-17-CS60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23497
EF-92-OO68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270844
BRD-K38358574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01103
RA-86-LI22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340935
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.87141
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GA-94-MC54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201715
CBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08332
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514768
CF-03-QN99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.509625
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4624
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pantothenic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68539
BRD-K76960970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57716
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319304
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.7088
DC-23-UM36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215995
DB-42-FS68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320797
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NB-79-SE70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356723
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2011
ZB-16-BR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.369846
COX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29694
GD-07-HO70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311347
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56769
BRD-K83690550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32753
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.895885
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14916
TA-19-YA45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15371
BRD-K63892351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37196
DA-10-VU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.863285
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33546
VA-06-DB75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.690636
BRD-K88642841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32735
BRD-K05090634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53883
BRD-K61274359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37545
TB-06-VB30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.630854
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.615
AA-79-SX47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.434689
BRD-K87131514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47467
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BA-84-TD72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.655812
ND-68-CU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.66729
PMC9490101-mmc3.xlsx-Sheet1-Supplementary_Table_3_Differentially_expressed_genes_in_CASC11_KD_MHCC-97H_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
XA-12-UL84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.486453
GSE206870,GSE206872_4_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.479954
MAP3K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49255
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DE-81-PO11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247438
BRD-K31222955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22803
BRD-K93613839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10479
FA-70-ZG69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314166
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13466
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-17-DF74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210638
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PD-71-MW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388231
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1026
EC-62-HO43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304012
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.526
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0077
BRD-K01358985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58712
BRD-K63668467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08136
AB-63-OW35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210086
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11717
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21949
CCDC93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72687
RB-55-KL42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.632877
BRD-K82115725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01302
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ID-00-IC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.805211
EE-02-BO83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.784451
BRD-K51502220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13266
PMC7439444-aba1972_Table_S9.xlsx-NR1D1_motif-Nearest_Ensembl_NR1D1	Rummagene Transcription Factor Associations 2026	1.0	null
BB-20-UU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07431
JC-64-QI43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399911
CE-15-YU05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203013
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07534
BRD-K16304302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74875
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IE-38-FB31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.619516
BRD-K25312635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08814
2q37 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
BRD-A11350423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86229
AA-62-HP31_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.795266
Golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K10775155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07302
BRD-K93391478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12575
BRD-K13559806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5381
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-10-GX45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393652
BRD-K63493628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2769
XB-35-TO54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427866
JF-16-BD66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.483148
BRD-K61929092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04869
PMC11758349-11130_2024_1262_MOESM1_ESM.docx-4-RFXDC2_RFX7	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A37796306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24783
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1621
PMC11442894-41467_2024_52678_MOESM5_ESM.xlsx-all_MSC_vs_iMPC-Unnamed_0_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
No annotation - 4	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35631
BRD-K40649636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03079
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00149
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09366011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.386
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EC-71-PH39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.391423
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03078
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.8309
BA-84-WN26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291558
BRD-K58217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5002
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HNRNPA0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79512
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.769107
BRD-K69698801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1379
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-04-NG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.878105
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.82092
HEATR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03876
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03033
PF-59-CY33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.526291
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433391
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.682534
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4981
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-55-CK61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318815
EF-80-OD07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224164
PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92079609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40634
DAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41067
DF-32-EL16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.594952
DB-40-HA40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.546817
AC-28-RT00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.870274
BRD-K06310280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14803
AF-80-GK24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.560832
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-SOX2_partners-SOX2_known_protein_partners_according_to_BioGrid_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83135
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77892972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23713
JD-50-EC04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232602
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6197
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63119190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22069
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21873
BD-61-OO16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.948903
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.897751
BRD-K82249895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68997
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.3066
CB-06-FE89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.709972
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-61-ZY95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.741596
JB-23-ZE86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0563
BE-17-CS60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21129
BRD-K47724892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82899
MA-58-RR04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.929065
ZNF331	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86301
BRD-K93874059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51196
BRD-K61189585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4342
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81937
CC-50-FK24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408824
BRD-K90999585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35189
BE-42-IC00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300838
DB-56-XL71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07218
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5021
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4981
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
AA-58-FJ71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.835456
BRD-K37527074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43119
CB-24-FA25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.377923
ZNF541	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39605
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25883
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46343
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6328
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.549607
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RA-42-CM42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214815
BRD-K51012353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18399
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
DA-17-XI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328336
AC-71-YF45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242306
AB-85-JR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.5058
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EC-01-PH79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.369059
AD-58-PW17_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.696328
KB-78-BE93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41849
S0-EE-Y97N_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33859
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395971
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350919
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00448
BRD-K31672963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07466
AD-58-PW17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237599
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330832
BBC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44711
BA-53-FM66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.644708
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BE-49-XN43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04998
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.174
BRD-K36397874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.081
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TNNI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1451
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04669
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9162
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46115
BRD-K06459664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54463
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30855
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-14-CG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250203
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240564
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.625903
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394395
UD-85-WR81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210832
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1786
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.828646
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.681239
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.901719
DD-73-IP88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371974
DC-61-QV78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314074
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12018
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37576
WB-17-DI74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471854
496100535_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41622
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
BRD-K00765599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78796
AE-32-DP61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442368
BRD-K21206585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01505
BRD-A04258855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67331
BRD-K22063616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44016
BE-92-TW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.96205
AC-92-HS43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.786333
CRCGN015_MCF10A.WT.HP_24H:F09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25718
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
LB-65-SM65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.735433
PD-50-SI33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306277
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77188
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39775
KE-04-OV29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.426943
FD-79-TC61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.588002
BRD-K77465015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93599
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-H358_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_H358_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87034416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52953
HD-51-KD29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361772
AC-75-LR63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11801
GNE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67782
BRD-K60296400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11874
BRD-K76336129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23565
S0-EE-YC7H_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383601
CA-37-NI01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.746529
KC-26-JQ92_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.467995
WC-59-RG09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.434432
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399487
GC-57-HV87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.552425
BC-81-LO06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302342
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7415
AC-40-KV26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2549
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43927
BRD-K77173942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28894
FC-85-OX77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329191
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4781
GNB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71648
HD-89-HC56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.949272
AD-72-RI24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244872
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253421
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35488
AB-80-CK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.508577
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.578234
CRCGN016_MCF10A.WT.HP_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03273
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.8571
BRD-K11188962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37884
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27593
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407193
GD-82-CS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.492345
BRD-K22537050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4342
BRD-K66526269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05638
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56968
DE-62-FI29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.767127
CRCGN015_MCF10A_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01487
BRD-K73840377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21416
BC-33-BM51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204546
CB-87-RB49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15056
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393232
BRD-K54879095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31896
HF-79-EC41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07606
PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07263
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34989
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5065
LC-12-VN85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.533862
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35208
BRD-K73319967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63349
ID-90-NM43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.839232
KE-37-MN32_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420467
BRD-K58930048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02658
TD-40-ZR64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273231
BA-10-WH12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.730128
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138815,GSE138817_3_v_1_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_1_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32973
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K57365604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69087
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BE-42-IC00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35391
BRD-K30436657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68625
Protein body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
BRD-K54099984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53509
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FF-07-FL63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236984
DD-08-NW42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21346
BD-69-XG81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410474
CA-00-AR16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04287
EC-41-PH99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.927917
DA-27-BW40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238558
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BA-59-EN38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475971
KB-49-NF63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292539
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286463
GPR89A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92025
BRD-K64183190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17297
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K39227064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15962
BRD-K11342801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0185
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477
BRD-K67426191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2179
PC-18-VX23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299575
BRD-K09975370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38088
NC-52-AG88_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214834
KC-32-GO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475812
BRD-K67859584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77463
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9249
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UB-62-DF90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296414
CB-02-XL81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00373
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.67856
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5905
S0-EE-XMXE_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267838
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2523
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.78114
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32267
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01689
VA-48-RJ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.620818
OE-75-WF43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257358
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.018
ME-64-LE18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393072
AE-19-BK71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213185
BRD-K64194889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91492
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DB-18-UF01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.837662
BRD-K44052748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18033
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FD-20-OG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442598
BRD-K54576503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11567
FF-96-HL81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223705
GSE185744,GSE185747_2_v_3_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
AE-04-SN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31903
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.919715
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.24346
CRCGN017_MCF10A.TP53.M_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21225
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46014233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03743
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07011
AD-11-RL84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.41371
SMAD protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.03
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9149
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24224
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_1_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-83-IZ87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430378
RE-62-FC93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225635
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11924
RAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67333
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.20405
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22918
BRD-K85235446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01873
AE-52-NW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.836591
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8563
BRD-K99939085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02934
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BF-44-HD37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22563
Human - Tonsil - L2 - Basal cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
KC-26-JQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.549346
S0-EE-YRH3_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303189
BB-23-AJ69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252025
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.719522
BRD-K85101688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.788374
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hydrophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.80415
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
FAR/SIN/STRIPAK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.114
CA-65-MK91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223591
NF-21-HQ00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.818902
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.981665
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19837
EA-84-SC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231835
BRD-K96249452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08885
BRD-K80858297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6317
BRD-K21732483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8408
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OB-78-PA58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394839
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81891
Dendritic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
BRD-A39660642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08291
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42637
BRD-K27287379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22327
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K45380779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36675
GSE215086_3_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
MIGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4327
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.79912
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.273
DD-26-VR55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.616974
EB-19-SM10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07726
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299116
BRD-K72145393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01667
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77052
GD-46-BU97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.977464
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.840712
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K66470464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41029
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K20026212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.36442
BRD-K95014129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09889
BRD-K53335788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36319
BRD-K74391203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08641
ELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76532
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73377
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
AE-14-NN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281603
FD-69-CC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239422
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.37691
HB-87-YY34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.607521
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8451
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AF-67-LZ82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.525334
CF-42-OS28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00207
BRD-K53094498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1104
CB-83-LF14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276161
BRD-K56699877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05324
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395248
broxyquinoline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12609
ZGLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02258
TE-26-XS06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2171
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0246
BRD-K06784595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13308
BA-86-AL61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209055
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.853092
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LE-60-VC29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.626039
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.746281
BRD-K76147162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.613
WARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7417
AC-96-OO08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07726
ID-00-IC14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.934518
COLO-357 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.57578
HD-33-CS00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.761208
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
BB-79-AG41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.538301
BD-25-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.997608
AC-49-NG46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.848053
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.43563
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-51-ZE47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.735093
FD-25-KX07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.659745
YE-80-LN04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.826043
BE-04-AN21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.784516
NB-12-ZK38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.649565
BRD-K13901498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00494
DC-45-WU45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208423
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.557
AC-83-LN99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23428
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.745992
BRD-K45343543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10345
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NB-12-ZK38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36126
BRD-K55218521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46119
chr2_240893740_A_ACTCTGGGGGCGTGAGGAGCCT_b38	GTEx eQTL 2025	1.0	5.59535
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YF-77-FV50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.75137
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6325
HD-29-LW24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230848
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13413
CE-95-YX02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.925694
KC-26-JQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33002
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04116
BRD-K11404512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04735
BRD-K75606012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20554
BF-49-IA57_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249284
BRD-K92569554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.31605
BF-22-EP86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.607447
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
BA-84-TD72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.772934
BRD-K60190533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69499
HC-11-RK51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254529
JA-79-II25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.491508
BRD-K60430111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22636
BRD-K41561756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06439
AE-07-IZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13971
DA-27-BW40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.485672
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459696
AD-18-XC14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559215
CRCGN017_MCF10A.TP53.M_24H:I01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3558
chr2_240896921_T_C_b38	GTEx eQTL 2025	1.0	3.57493
AD-51-LE62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.424919
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3199
BRD-K48540267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00701
KA-63-FH23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.697675
FC-22-VC55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41139
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.999762
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26474
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.60301
BRD-K67126097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01081
OC-40-XI13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.901056
BA-28-XM73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.671456
BA-95-YU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.600939
PMC8566473-41467_2021_26653_MOESM3_ESM.xlsx-SOX2_interacting_proteins-Gene_symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16062794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00993
BRD-K65112040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2753
CF-42-OS28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.866781
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
POFUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.994
HE-16-PO98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343048
BRD-K68160857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23725
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32521
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21511
SA-31-VB03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.472049
GSE166004_7_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DA-66-OE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.627916
496100377_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58948
BOLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48403
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.31002
DB-56-XL71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00467
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4544
YC-57-OY42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307622
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.166
TA-25-KO99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235496
ZMYM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3909
BRD-K59957885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13999
FA-23-LP18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22899
BRD-K12181036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21886
BRD-K47966145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5713
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190864,GSE190907_1_v_0_cacybp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83479
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.684115
XB-53-OZ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.992928
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-520-ENSG00000144485_HES6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21216
AC-33-YJ09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307758
BRD-K87929769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53994
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98075
BRD-K68495784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43253
AD-54-FG24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.980467
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.934312
PC-62-AQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.883141
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HA-32-YH61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.548594
AD-16-HL96_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315544
GSE254770_3_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27147269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00893
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.900928
AA-80-XK94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.493357
BRD-K95553255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79673
SD-82-GT69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.640956
BRD-K03713632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25756
AA-30-BE85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.630978
BB-94-HN41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255732
BRD-K18601936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33622
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KB-48-GH25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.501199
BB-41-XE67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401567
AE-71-CB15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203648
JD-62-HR05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.675589
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
QA-34-PH05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.642417
NDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54462
BRD-K94088690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20644
KB-78-BE93_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359661
GA-77-MH38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22206
BRD-K04317371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13689
ZE-14-BN99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50029
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239883
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04
DA-69-UN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.609231
NB-80-IM48_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2075
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05325
DC-23-UM36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.718681
BRD-K61034310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96456
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.727765
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.921615
AA-30-BE85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285877
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08219
DF-00-BX35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.301
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.366
QA-14-AU91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.37131
BRD-K69132276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28706
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25124
BRD-K86463534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52888
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.805244
FE-29-XM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220764
FD-29-MM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27092
HA-17-MS45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.675083
BRD-K21678546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16925
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11036
BD-69-GX17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322445
BRD-K12460566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97297
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5651
HB-54-ZC59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.594563
RB-80-RO52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356268
BRD-K92172862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41507
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.522978
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75133
BC-13-OQ01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41317
BD-58-PW57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330491
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.081
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45628030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29953
SA-03-IQ14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.552864
AA-22-UI44_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.626193
BD-01-RI07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.497625
EA-81-CR68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.618649
BRD-K99783492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03068
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZB-29-GC39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285656
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PC-68-HN64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05347
BRD-K36465335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71248
Venous hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7178
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA-25-LR28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.467941
BRD-K32680124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07563
HE-16-PO98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.756565
AA-85-LB25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353532
BF-63-NG22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23183
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
BRD-K71005143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1167
GSE230174_0_v_1_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.24432
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8038
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9584
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00122
NF-21-HQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22605
BRD-K26720280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50346
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_4_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371733
CB-02-XL81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.820605
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
JA-85-SW39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2483
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559644
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.75201
BA-15-LA22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.386514
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.9184
BRD-K61283064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0129
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16800391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82598
DB-21-FY75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256303
ZB-29-GC39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272342
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04862
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZA-28-BF44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.771393
BRD-K75985122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07628
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67985577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36176
HF-25-LA47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208744
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277301
non-severe COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
BRD-K36228696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41766
AC-50-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.878575
FAM120AOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80984
BRD-K00970182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78329
BRD-K20061970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51315
PC-87-OG75_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306651
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28373
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23665
BA-95-YU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308603
BB-42-FF52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19749
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50178
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05553
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26342
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
DA-10-GX45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.671664
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RA-49-ZB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294313
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7127
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23096
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2267
BRD-K82863660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45245
BRD-K78658063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20223
PMC10539177-41375_2023_2003_MOESM2_ESM.xlsx-CCF-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
BC-75-CK91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24241
WF-96-ME07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15574
Human - Tonsil - L2 - FRC	HuBMAP Azimuth Cell Type Annotations	1.0	null
CE-69-HJ13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31838
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236744
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K78196882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10617
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33465
AB-14-GQ48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223145
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8925
BD-38-QC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.50443
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K48406740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10038
JB-63-NV02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427163
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05113
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
UB-83-HM84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.57804
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.917559
CC-31-VS31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331102
FF-06-MO73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415304
BA-88-HT15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432537
BE-42-IC00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.446071
MF-37-KQ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.902094
BB-11-JI42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.761901
496100512_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19874
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.53412
EF-01-LB20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207578
EB-09-GW59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291995
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-85-JR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.608033
FB-12-UL66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466532
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0663
PMC12081637-41467_2025_59822_MOESM1_ESM.pdf-50-XBP1_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GF-35-IT27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.908812
AB-82-ES53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404636
BE-90-YK54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.913704
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.678699
CE-18-AP85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273548
BRD-K15434241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32887
BA-39-HG26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.56888
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.960813
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4354
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0587
BD-69-XG81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.849873
RB-22-TT44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278376
UD-07-US73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.678852
MA-43-MR37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559506
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5444
GB-46-CK08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239258
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.441416
GA-87-BR97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.697287
AA-68-OJ16_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392515
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.744147
BRD-K85336956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23803
AD-29-IG16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393655
FE-29-XM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11798
HE-16-PO98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.446736
SIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40425
BRD-K55648964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17802
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230531
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31870622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50443
PDIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4079
DC-87-HI21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.696275
S0-EE-Y6YC_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207062
PF-59-CY33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.705702
LHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04555
AA-62-HP31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273837
CB-55-AK76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.842348
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA-48-JF51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.775852
Annular pancreas	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.337
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46738
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AE-51-ZO26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361537
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	162.238
FD-15-HD09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347601
Nucleolus organizer region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
PPFIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42905
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11712
BRD-K34985075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06781
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355331
AC-28-RT00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.48406
SEC14L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19325
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0978
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01201
WARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03859
PF-59-CY33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.987552
FB-33-LI31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272108
PAM complex, Tim23 associated import motor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.823
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9065
TE-26-XS06_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201827
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
QA-34-PH05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326708
DB-18-IF31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203166
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293913
BRD-K45221651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14781
BC-09-JG96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.681833
DB-24-CQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.992621
CB-24-AT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362146
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.711037
AA-56-QO38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553862
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.887139
PMC7439444-aba1972_Table_S9.xlsx-NR1D1_motif-Gene_Name_NR1D1	Rummagene Transcription Factor Associations 2026	1.0	null
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.601302
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268366
KB-78-BE93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00656
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387247
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PF-84-RH50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242776
GSE169155_6_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DA-40-HO94_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220211
MC-51-BT07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269423
BRD-K06330738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29402
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.41862
AA-48-XT80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35188
JE-22-JR20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.573816
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0918
BB-23-PM31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26521
BRD-K04819729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12837
BRD-K64147309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70651
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AD-30-VB23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250427
BRD-K79521948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27677
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	6.52567
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249115
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9831
BRD-K13068347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03861
BRD-K28433349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38979
GSE211744_8_v_4_gdf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K31269097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28008
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GA-47-MH68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.366948
PMC11530610-mmc3.xlsx-WGCNA-RORC_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.3533
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.30889
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Lysosomal function and lipid metabolism	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
BRD-K23836639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04417
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0198
BRD-K02070226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25327
BRD-K53101279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0257
YC-45-JD42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.92106
MA-58-RR04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.613342
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46607
BRD-K06148713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75937
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03835
RA-42-CM42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.449453
AA-10-VR76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313188
PMC11659402-41523_2024_709_MOESM3_ESM.xlsx-Sheet2-Down_genes_in_ESR1_mutant_within_top_10_and_consistent_in_at_least_40_comaparisons_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15502859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01371
BRD-K45097650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34053
BRD-K11844860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1608
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247441
TA-19-YA45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355055
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402526
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.550298
DD-08-NW42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367506
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.68673
KB-92-MK13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.87409
BRD-K45358679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40989
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.74551
AB-25-XU75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307957
CC-04-FJ21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4911
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.893457
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CE-03-YQ91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203928
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36561
BE-73-KD75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.611154
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A34891365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71831
BRD-K15708264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09439
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05313
BRD-K95500312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48206
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204671
BRD-K56224420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.131
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.52429
BRD-K13350372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08056
Duodenal atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.998599
CYCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53451
BRD-K41033271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01837
BRD-K58220566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27501
BRD-K01554997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29022
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.58615
BB-20-UU03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.443519
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32963
GSE167474_2_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-57-NT83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258409
BE-31-XV38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15745
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.951321
AE-88-WQ63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.721239
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.806841
BRD-K19237647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24845
HD-19-IW09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.928372
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.52328
BRD-K92311828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51399
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AF-30-GH67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.647
FA-89-PW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.597639
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8683
CRCGN017_MCF10A.WT.HP_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.97285
SA-43-QT61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254776
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YC-45-JD42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.450519
AA-03-QM41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.525181
DD-54-MA35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29864
TB-06-VB30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.423734
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55012
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.3903
BRD-K45328741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45129
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.984256
DA-23-TZ42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408876
AD-52-UZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.571309
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.73714
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
BC-15-EL49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30422
VC-19-YG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.39962
CD-05-PU90_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251459
FA-10-SN61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33228
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12715
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2986
PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE78199_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-BRCA_AND_CESC_AND_UCEC_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BC-13-OQ01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415927
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.709327
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7278
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.844626
DA-58-LZ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237543
GSE157049,GSE157051_7_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90221
MAP3K20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34614
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.33434
ED-05-KX67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363514
AB-80-CK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.852147
GA-59-RW04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.618424
BRD-A54769817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16201
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.837492
ERBIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67811
BRD-K76616863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09258
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.34228
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.086
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VD-88-MW70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.53891
GA-81-DL34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311101
NA-29-UI75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25581
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.836028
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DA-81-VY50_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281562
HB-92-XE24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.660302
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UC-80-UO92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.496675
BRD-K63665694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09797
BF-10-IO69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312554
HEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31482
BRD-K47716724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07151
MB-15-ZF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.885372
BRD-K83708664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0802
DF-93-BT88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.683324
BRD-K73573090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18196
IGF2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73669
YF-00-IN39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.656547
NLGN4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78852
AF-33-HJ54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284733
GSE155162,GSE155169_1_v_3_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
QD-32-CW16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.366152
FD-48-HZ39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.787822
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01484
CD-41-RE87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.721623
FE-82-WB22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.971939
DB-07-WB29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558122
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408924
AA-62-HP31_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.729177
BRD-K64730761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1452
H1-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.760301
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.863515
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.892696
BRD-K90149465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16444
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.377525
BRD-K07662722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01777
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-82-PP66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302122
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	1.0	null
AD-06-OB47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267912
EF-01-LB20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.510451
BB-16-BE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.39786
BRD-K02802091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0972
BRD-K55169051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44244
GSE241701_1_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JD-87-KA71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333672
BD-69-XG81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.677189
BRD-K32191695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22557
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
HD-33-CS00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.960581
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29655
BRD-K52613522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71741
EB-47-BB89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272239
BRD-K14375790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49323
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.428735
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25427
BRD-K51858914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48791
BRD-K94845132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46453
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TD-09-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334724
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-09-YX02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27817
FOXJ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45178
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24322
BRD-K02959126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0079
BRD-K44141416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71139
CC-03-PW00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411614
BRD-K10784927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3033
BRD-K31030467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1788
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28207
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.650553
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55841827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47366
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36476
GSE153189_1_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EC-89-AJ93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.617816
ZA-63-AC60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.497451
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3771
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223371
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6125
KA-81-AG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346597
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299286
BRD-K67750179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02343
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.699018
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15111
BA-69-TQ80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.652387
KA-72-WY22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448495
BB-28-CT35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252087
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.638362
GE-29-ZM45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.757999
AB-04-NN16_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201496
BRD-K15742845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0171
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OC-71-BZ81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.820717
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07036
AD-86-OB87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.681747
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332879
HA-53-FL63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.784377
EF-85-DA07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324265
RB-55-KL42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.955234
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.767965
AF-30-GH67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.701991
chr2_240899864_T_A_b38	GTEx eQTL 2025	1.0	3.46709
DB-18-UF01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.718596
VA-19-EX85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.424553
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08186
EA-18-FP00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282988
WD-62-UB45_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257404
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294089
AA-62-OC45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378662
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A19912945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.047
CB-32-EI69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.584317
BRD-K44026015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15072
BRD-K26591929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35567
CF-42-OS28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.789138
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39178
JD-38-MY26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.74624
FA-36-VA24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.906593
Parametrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
GE-34-TW62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246074
BRD-K56258950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34281
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.570013
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380576
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.643087
HD-51-KD29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.439368
BC-43-PD20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.596651
AA-68-MW92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335274
PMC11244912-media-3.xlsx-Sheet2-Down_genes_in_ESR1_mutant_within_top_10_and_consistent_in_at_least_40_comaparisons_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
SB-28-EJ14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.616885
CRCGN015_MCF10A_48H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6362
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02646
HC-92-HE59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01722
EA-95-OQ30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.439103
S0-EE-YEKU_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.605028
CC-18-YW57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.58704
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28307
ZNF304	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74218
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.699863
OB-20-LP90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219835
BRD-K21450593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49946
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.729904
DA-35-DU85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.56652
AA-99-PN83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303989
ZNF875	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08366
BD-69-XG81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27424
DA-32-QL71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332188
BRD-K14037093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12847
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.51451
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3743
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
KC-32-GO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.582187
FF-34-KW62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.57092
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.51765
BD-41-DI77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284939
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78022
BRD-K52592505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6688
BRD-A06327019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03908
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.70286
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03041
BRD-K65626032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.107
BE-07-IS45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24302
BRD-K76763044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3489
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.733
GA-04-JM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.662664
CA-63-LW25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05454
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.37661
CB-44-RT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.586311
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-59-NQ20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440868
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412296
XC-65-XN91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383579
SA-03-IQ14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.920579
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.84201
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21589
DE-73-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.59442
TD-48-XJ84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.647481
BC-13-OQ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.217
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21473
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559873
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26681
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.59537
AE-13-CX28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.492084
AA-58-FJ71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.485442
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20655
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
EC-89-AJ93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.588518
OB-15-UL37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36459
CE-72-GF32_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.648258
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A02214146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06788
BRD-K92195351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62861
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40792
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.939183
DE-48-HZ49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.847473
BRD-K84320538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58322
FE-06-GR60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433998
FB-91-BU05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.835149
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3519
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.688537
UF-28-DW05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297217
BRD-K95963125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0245
HC-76-HU27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338773
BRD-K82068522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12327
PA-15-CI45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41091
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.852517
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
GSE172146_2_v_1_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.34301
GSE110802_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YA-92-YO01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383163
PD-60-FM93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445903
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
RB-55-KL42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216674
BB-93-VT73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27092
EA-93-KT88_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319556
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZB-09-RC84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.529007
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00705
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60068268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15483
Lung function (FVC)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3
BB-28-MC54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306276
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8737
DB-18-UF01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257598
UC-52-SS41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215251
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5976
plicamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.01247
BRD-K52473839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13145
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZB-29-GC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.597524
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96725
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
AD-31-PI82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411912
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BE-27-XF09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.905333
BRD-K64222382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37528
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EC-37-MB09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206017
A-431 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
GSE241701_4_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K42653521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08706
BRD-K71537579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16865
AB-85-JR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.598049
MA-31-VM30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.531657
VA-92-QP54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379408
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553564
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21263
IB-56-JN40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.717289
GSE211241_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7810865-41598_2021_81000_MOESM1_ESM.xlsx-S3E-Unique_to_KIS-1_EBF1_-DOX_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_RORC-Logfold_change_threshold_1_0_1_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7064337-elife-51373-supp2.xlsx-652_genes_up-regulated-List_of_652_genes_up-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28107038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62633
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455965
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240352
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1627
OD-03-CA36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.6344
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193027_1_v_0_krt19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
t67-small-intestine_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.62039
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02008
UC-58-DM11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298311
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.75766
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.6721
FSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95183
BRD-K70380532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05142
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418744
AD-06-OB47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201034
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47279
QA-34-PH05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13329
BRD-K19651468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14872
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.377993
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23152
AD-55-WK61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301124
HAE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
AD-86-OB87_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.562148
EC-82-LV30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.92404
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
LD-14-PB06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.809956
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.44771
JE-22-JR20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.945665
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.852269
HC-74-FM38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.46422
CA-73-BW50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315306
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21295
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336767
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
NC-11-BC71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309597
BRD-K66802550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02889
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3371
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.369904
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SA-32-CC58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332293
PMC10175786-Table4.XLSX-Sheet_1-GSE9750_AND_GSE63514_NOT_GSE7410_NOT_Ferrotosis_genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85996308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17012
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21018
HE-80-BQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445272
NPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81711
BB-11-JI42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208895
GSE200897_1_v_0_pold1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K19645475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02674
CD-96-HO43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.679562
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kmp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.561753
PD-71-MW24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221418
LB-67-JK40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270036
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162276_2_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CC-50-FK24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.66449
AD-42-US78_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.723577
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.728911
S0-EE-Y7IR_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.446832
OA-54-FL10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38173
DB-34-KT45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334735
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25078
GC-07-UO80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229838
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.957706
BRD-K62000282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24083
CB-55-AK76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.661755
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CF-24-KQ98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.615657
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.6622
NE-00-JZ19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.873212
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6192
chr2_240880109_C_T_b38	GTEx eQTL 2025	1.0	2.57531
BRD-K97337407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35367
DE-98-FC24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374028
BE-45-VH04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205382
BRD-K84593579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00767
BC-61-ZY95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448797
PMC4609150-13073_2015_228_MOESM2_ESM.xlsx-TP53-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146840,GSE146842_3_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NE-34-OZ69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440496
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12108
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.424744
BRD-K23430426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60697
CC-47-VS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231445
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DD-38-BM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471878
BRD-K26844643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00198
AC-36-TL21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345778
MF-81-RJ18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.456008
IF-31-BQ95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253764
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49537
496100312_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09396
PMC12358297-41388_2025_3481_MOESM3_ESM.xlsx-S9_ASCL1-regulated_genes-Unnamed_1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01324
FA-47-IB34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300988
DC-78-CM38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18316
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-18-YN11_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.527073
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19812
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252795
GF-35-IT27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1179
CA-68-TC79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.814839
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.765809
S0-EE-Y6WJ_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.854253
BRD-K94777797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27544
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.377
ZB-33-MZ40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.470591
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02795
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71808107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30417
BRD-K70565285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43107
BRD-K94936556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18591
RF-36-EI47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.458821
BRD-K70851916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83618
BRD-K11757577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14164
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.525282
BC-00-YH62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.646705
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.69764
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.749008
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17774
PC-62-AQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299153
FA-16-HR75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223281
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1992
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.691275
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	228.896
BE-81-QL64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276553
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.5152
BRD-K45811188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68672
AB-30-CR11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.598333
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6667
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HD-18-YL30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.926785
496100598_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43618
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.781579
496100530_FWM_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42043
CE-18-ZM38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2315
BRD-K22065327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05305
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FC-62-AI14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203319
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00591
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.908901
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.542141
OC-10-FB51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.551009
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410225
XD-44-FJ34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.416972
AA-49-BD04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.968853
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.914
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.598692
DA-83-VJ09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.889037
PB-09-OE00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.9401
YA-44-LW45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35107
BRD-K06845853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28158
UE-58-EW15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414748
AE-28-IQ88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31855
BRD-K74314059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83964
ZA-63-AC60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.838427
MA-32-UX14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222881
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00677
BRD-K61370861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2279
WC-09-GD62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03079
BRD-K74803017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20298
BRD-K63299069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25276
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40991
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CE-35-LA42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.441503
ID-70-SM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0892
BE-71-AV63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.782644
AA-99-PN83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28743
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.655546
GSE78199_2_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74689
QB-88-PG52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.833891
YF-00-IN39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09354
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.981848
UE-02-UW61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.821591
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12427
BRD-K02321382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52606
FABP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78243
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8588
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99792
BRD-K06529600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92272
BRD-K90040724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29434
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8125
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9441
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9992
BRD-K97741413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73863
BRD-K23118252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53212
AC-50-FR41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25713
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263853
DD-38-BM78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35977
GSE112760,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.489816
QE-00-EB96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.604303
Villous trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.42776
CB-88-LG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432378
BRD-K67211407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11308
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02036
BRD-K75990394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22105
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
FA-36-VA24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397986
CRCGN014_HEPG2_3H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3429
EA-93-KT88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209059
BRD-K01717817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26881
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40783
CF-97-AV07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265364
Prostate adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.798917
BRD-A19615705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06519
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.921293
Familial hypocalciuric hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A81879813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26717
IC-18-TY61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.457013
DB-24-CQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.543093
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53993775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66759
PMC12381255-41389_2025_576_MOESM2_ESM.xlsx-Progenitor_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
JE-55-OJ53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430489
BA-88-HT15_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268397
BRD-K69252983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08786
BRD-K39858575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35215
GD-46-BU97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.496009
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.763071
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8568
SA-32-CC58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.694353
PMC6488577-41598_2019_43010_MOESM2_ESM.xlsx-Proteingroups_MBD3_pos-Gene_names_MBD3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8384902-mmc6.xlsx-DEG_ASCL1_3TF_shared-GeneSymbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06308228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09588
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3347
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23447
GSE162276_2_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LD-69-ZV56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11601
CILP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68263
YA-85-VH07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.761366
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_lost-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Multiple endocrine neoplasia type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.9988
DE-85-LX22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.456875
BRD-K44212150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48302
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49707
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.787152
CA-66-YB17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451652
BRD-K78618254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01247
FA-36-VA24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277211
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.633834
AB-30-CR11_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.524742
BC-00-YH62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12054
BRD-K40206099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62765
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38510068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10685
AC-36-TL21_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.490941
BRD-K40630587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20135
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206763
QA-98-TQ46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406452
AB-82-EP26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.648426
NC-52-AG88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.992748
BRD-K86050213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27364
BRD-K31203610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48046
LA-44-KW22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413844
CRCGN017_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5694
JD-62-HR05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.895677
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
FB-24-UT80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331447
PMC11059513-mmc1.xlsx-Supplementary_Table1-Table_S1_The_gene_profile_was_down-regulated_after_HIF1A_was_knocked_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.655497
SC-25-HE80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559603
WC-59-RG09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224126
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.419199
QB-88-PG52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375512
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.405138
BF-26-MB27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.667835
BRD-K20278539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40718
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26154
CF-48-QD87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.894401
AA-39-BD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410593
KE-24-RZ94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.790752
SB-29-ZH97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221898
Pulmonary alveolar proteinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
FD-59-TC81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.676118
RD-79-FH72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330252
BF-49-IA57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558829
LA-86-XT29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.615078
CC-44-MG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.803126
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1166
IC-05-WD74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210449
RC-52-AC88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484155
DA-10-GX45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.853226
WC-67-DI84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.527635
BRD-K20142115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26179
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.539125
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07755570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44575
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4825
AE-85-KE62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.454894
DA-07-LL18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361685
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.539557
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213650_0_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
FB-33-LI31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.39308
RB-34-TO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.800838
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9381
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.715999
BRD-K77203880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12252
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ND-27-UQ99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291552
BRD-K88388723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29027
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.42995
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.85989
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.42517
DC-93-NP78_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308959
BRD-K10635555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03243
GSE233441_1_v_0_tnnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FD-62-ZB67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.590782
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371425
AB-00-IL62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.521977
CRCGN017_MCF10A.TP53.M_24H:M06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11587
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8475
EE-18-HW72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272534
BRD-K15867859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32407
Nucleolar chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
BRD-K30013451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2373
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-58-PW17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.465102
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178340_1_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-40-HO94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.813697
Kc cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
ED-33-YZ72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.417208
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CB-02-XL81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.856115
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.525852
BRD-K12862541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84624
HC-38-KI38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214101
GSE195663_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-97-BI36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.10444
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21521
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48795
BRD-K78106941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04506
Cervical incompetence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.532853
BRD-K73858940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02116
BRD-K86537726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53791
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00305
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
BRD-K39291909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19613
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412166
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.4557
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04823
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395207
GSE199541_2_v_4_mbd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.709953
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDK18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39105
AB-30-CR11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.2783
DB-34-KT45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201313
DF-00-NA25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.840211
BRD-K97462883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55674
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42933
GSE98755,GSE98756_3_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.546931
BRD-K19429335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47393
YB-58-IZ37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337196
BRD-K68301602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10387
TC-02-NZ28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263152
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DC-22-OP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13103
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01909
CB-73-HZ47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.607187
BRD-K87790666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50281
DB-18-UF01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4477
BRD-K93543569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3681
HE-22-JR80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31333
FF-46-OR35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514923
BRD-K60907484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13031
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3229
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-KLF5_Direct_Targets_PDAC_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
WA-03-IF37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317191
BRD-K64559139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29348
BRD-K16266179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51885
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.59934
FA-88-II68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.568411
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AE-32-DP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02488
GSE206870,GSE206872_4_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-58-PW17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.93953
BRD-K47370004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18179
YA-85-VH07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.945717
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-18-XC14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.580081
PD-26-DC63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.658753
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.77531
PAX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86071
BRD-K60759770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1355
BA-50-HH67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.634808
BRD-K35975002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01309
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151160_0_v_1_cd36_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WB-17-DI74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.555174
GB-01-UN23_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318761
BC-15-MR23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280608
BC-02-WF67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233105
PC-68-DU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.5466
CF-81-DS26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10857
CRCGN017_MCF10A.WT.HP_24H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1074
BRD-K15523383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45453
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7382
BRD-K49040541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17025
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.733
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
ED-02-CL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277522
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.622149
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JB-14-ZM03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.761768
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DB-29-HQ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249055
DA-80-IV36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339619
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4594
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
BE-92-TW08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.985364
KA-51-CQ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25242
FD-86-NE74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331615
GB-73-QS80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.665872
GSE166783_4_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207865
DB-34-QA60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338382
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5986
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277297
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
AE-67-DS75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407376
IC-05-AW29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33543
BRD-K50045638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23818
BRD-A44990218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20258
CRCGN011_HEPG2_24H:C03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51595
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59695
TD-31-KS49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255039
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.883717
UC-68-LC67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390806
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91043938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47864
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365043
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.82968
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5297
HD-29-PZ41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.534323
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.752029
ME-16-XW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224965
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VA-03-RM19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20186
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K14041149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76092
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-81-LB65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07984
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.1732
Mpf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
EC-98-KI28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.649144
BRD-K63058274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27517
TECPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20374
BRD-K41289356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02003
BRD-K37356599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19124
FE-69-HJ93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623332
OB-17-DQ74_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218523
BRD-K95810752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01196
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5333
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.961024
BRD-K58996625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14489
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45586
JA-79-II25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475401
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38046
BRD-K56149020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13069
GSE112860_3_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mdamb157	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
BRD-K92795658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65374
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262972
XB-53-OZ95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.613664
EE-02-BO83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.636339
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.812511
NE-95-RP07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.780777
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66717
BRD-K48059443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28888
chr2_240889832_G_T_b38	GTEx eQTL 2025	1.0	1.59096
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.716747
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.979347
AB-71-CI37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.605391
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.365
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100473_TCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28621
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FD-72-CE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.794041
AB-85-YK41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.821115
BE-04-AN21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303212
AC-92-HS43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26004
EF-92-OO68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.565817
AC-97-KP88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35686
Ski complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.103
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38324
GSE225083_0_v_1_kras_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29518
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8354
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.967044
AD-53-VC77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321059
KE-18-XY06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328072
AB-12-PP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226421
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
AC-75-CE67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.569716
PMC6802116-41467_2019_12517_MOESM5_ESM.xlsx-Sheet1-D9_8_GNF2-SERPINB5_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97700172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50235
BRD-K58735963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07513
BE-25-UR78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205435
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26369
HF-91-IU60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.366733
BRD-K98968761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21758
VA-06-DB75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.702199
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.850199
CB-06-FE89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.479078
GC-69-JF03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231934
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38209615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57605
AD-00-WA10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.944596
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.487548
GD-82-CS38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.869515
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0972
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.775781
BRD-A24223049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53235
BRD-K77797840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58609
BE-59-WG31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322713
BA-68-FJ41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514937
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7529
CASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31421
AC-83-LN99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.642772
BRD-K91467861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05709
CA-66-FY97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.608233
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87887
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.82951
AA-86-YY62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.452581
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.75993
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28682
GSE178532_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239539
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8474
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16064200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16409
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.73639
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4188
BRD-A77292814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79155
GE-40-VJ66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.457768
BRD-K64763786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04896
JB-09-SI50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445959
CE-96-GH46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.724969
BRD-K09258973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16023
Human - Tonsil - L1 - Epithelial	HuBMAP Azimuth Cell Type Annotations	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.991221
BRD-K92433763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00254
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.704057
SB-94-ZA83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284417
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36007
ID-90-NM43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664708
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3623
BRD-K92767663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24435
BRD-K72161690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82677
PMC11625982-AJH-100-10-s001.pdf-28-ZNF680_ZNF680	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HA-32-YH61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.656912
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BE-68-PM13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427879
CITED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0504
JE-04-LS32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324121
EC-89-AJ93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293464
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BF-54-GX35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.953212
BD-17-LT43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301679
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445284
BRD-K63730594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5085
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EE-85-SK26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244464
JD-87-KA71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.31038
OB-65-AI50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.871557
CC-90-NK44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259849
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GC-42-LL86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.613977
BRD-K69438930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36711
CB-32-EI69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04995
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41972460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12253
FA-80-DR66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.897324
VD-76-SO91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.896478
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.701199
GSE176472_1_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01638
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371991
GC-46-CA74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.608642
SF-67-CJ22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.531181
FD-62-ZB67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223343
TD-17-NF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40107
EB-67-WB79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.627329
GSE157049,GSE157051_6_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.823
BRD-K59870481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48424
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20022
BRD-K54554531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60037
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22153
FEV1	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
BRD-K33979719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19194
AA-52-JS03_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296346
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.429149
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1365
BRD-K63030320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36755
ED-35-EX82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.819535
SCARF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13478
t67-small-intestine_female_1w	MoTrPAC Rat Endurance Exercise Training	1.0	3.4205
ADPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63399
AC-28-RT00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.636787
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41855
BBX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43136
EF-73-IP33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210799
HC-74-HM63_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.788159
BRD-K78972225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27574
CB-92-VC05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21777
BB-23-PM31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234845
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224595
CCNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46479
BRD-K35472285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25863
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26835
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PD-94-WO47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01715
JE-72-KV75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397754
GSE152032_3_v_2_s1pr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77041516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52887
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.811654
YE-55-YX75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.70512
DA-28-TM43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.582234
CB-55-AK76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.698478
BRD-K70886325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10172
XD-08-ZW85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330992
SUCLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81079
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.662027
GA-28-SS67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.617035
AD-72-MJ27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.808799
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100560_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02391
BC-74-QN56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.895147
BRD-K65932559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27201
BRD-K32362211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68642
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22889
JF-96-HH81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.824119
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DD-71-LY65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314763
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36155
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.87722
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278239
OB-01-DJ93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273406
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.86195
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FC-35-BX82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51088
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.721222
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EB-44-GM58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399951
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.7471
FB-95-JD99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342346
BRD-A37523642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59816
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31408750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04722
VC-19-YG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.396655
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
SMCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95653
FAM234B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13901
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A47137250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12194
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BC-13-OQ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.93231
BRD-K28623804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09539
AE-32-DP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.70255
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
NA-16-OJ70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.546581
ID-69-QF93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406678
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.716217
BRD-K23963854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32489
BC-51-ME52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280819
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WB-54-WD35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.585747
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16575
BRD-K00218068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00686
BA-77-US35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.463293
ZNF48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73525
GSE225447_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25529
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HA-99-UT82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21423
CRMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61004
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-71-HES6_HES6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51978501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2585
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477824
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-58-RM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251617
AB-71-CI37_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232666
S0-EE-YNU4_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238079
CRCGN009_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31319
BRD-K44799944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36425
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03406
BB-86-BE39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17914
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48034
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_lost-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DA-88-JF21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.504461
DD-74-PJ26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295773
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.645
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.891
ZNF672	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20252
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13087600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04692
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44345
DC-23-UM36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383835
AF-00-QK19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.858849
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07688551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56398
DC-72-IB32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310932
GB-64-HC34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.601762
BRD-K44509164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25492
BRD-K26272845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08014
JD-00-YJ41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234237
BB-64-EE60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403824
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.68285
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.9825
BRD-K60057192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03365
CE-03-YQ91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430102
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.696
C11orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82446
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9467
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265858
BRD-K66413698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49893
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-51-WE27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277239
LE-80-BM08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.761057
VA-48-RJ44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207337
BRD-A55153871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53657
AA-68-OJ16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305245
DC-17-ZB19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.557291
CBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23501
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JD-58-MV19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.625106
EA-62-MI89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.68988
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
RB-55-KL42_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.511703
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CE-37-XI06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477181
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412734
NF-24-NB76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.883114
methyl-salicylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02031
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336584
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	261.636
KB-46-EJ60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302476
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.85409
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K45732260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04251
S0-EE-X7LX_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.351351
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.0568
BRD-K40276277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4029
EC-67-PV87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.635057
FE-61-DL94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216892
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4484
CRCGN008_HEPG2_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13255
EC-89-AJ93_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10473
S0-EE-Y6WJ_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.616379
SLC25A38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80449
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BB-78-LT85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274433
BRD-K13486159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16793
GF-37-MB64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12224
BRD-K40019775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16203
BRD-K16598630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9004
LD-39-FL02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.909548
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.753115
EA-73-UC67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.424903
BRD-K18519621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47641
BRD-K93663012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41395
BRD-K88384015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83813
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OB-17-DQ74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12643
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92597
BC-76-HY47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342394
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4139
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JA-85-SW39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422809
EA-02-ZO63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245088
GC-40-VJ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408322
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
BD-90-DK64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.485002