association	dataset	threshold value	standardized value
hsa-miR-4753-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
hsa-miR-204	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GF-35-IT27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207675
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.830338
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_5_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.901
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6229
NKX6-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30686
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12984
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945714
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19215
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23558
Esmolol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
estradiol_homo sapiens_gpl14550_gse35034	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13894
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1778
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.624346
HS616T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69205
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17291
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913702
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.18421
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09275
MYC	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17153
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8488
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81771
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979843
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SBNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.30666
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00786
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909771
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277166
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942672
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-20a-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85771
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-AB2X-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-552	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.873536
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62285
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4402
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	2.25129
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UMUC14	DepMap CRISPR Gene Dependency	1.0	2.10766
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071014
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.0419
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15675
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.669657
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06542
E2F6	ENCODE Transcription Factor Targets	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	1.93085
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04106
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850589
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444147
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75452
Glycosyl hydrolase family 99	InterPro Predicted Protein Domain Annotations	1.0	null
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6078853-molce-41-7-695-suppl2.xlsx-Sheet1-Table_S1_Genes_exhibiting_two-fold_changes_in_expression_between_WT_and_CTCF_KO_otocyst_with_FDR_less_than_0_05_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34009
an3ca	HPA Cell Line Gene Expression Profiles	1.0	0.903027
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07915
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053813
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3044
AFDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94265
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
COLO320	DepMap CRISPR Gene Dependency	1.0	2.0346
EZH2	ENCODE Transcription Factor Targets	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
3042_FCF1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.576778
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3151
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.23922
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_16423_KD_AUF1_SRP224925	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844468
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054031
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10811
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0054
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061959
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_1_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48332
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Osteopetrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20589
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13057
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.97348
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933942
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47114
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06333
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-27b	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.238
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52622
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935753
GSE220520_3_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CA-90-RU33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210357
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3887
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00498
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308274
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276145
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856083
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16136
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899691
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
TRIM28	ENCODE Transcription Factor Targets	1.0	null
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7307
GSE189941_1_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63594
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NACC1	ChEA Transcription Factor Targets	1.0	null
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.55955
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BC-13-OQ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225624
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0009
Brain Lower Grade Glioma_LGG_TCGA-CS-4943-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0384
OE33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37642
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75453
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.1246
GSE224131_3_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39949
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20233
golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
VD-76-SO91_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235839
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4638-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45217
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13231
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223177
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7913
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.22485
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE169356_0_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49998
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3518872__F3	PFOCR Pathway Figure Associations 2023	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825072
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.01852
membrane part	GO Cellular Component Annotations 2015	1.0	null
GSE133927_1_v_3_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TB-06-VB30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265576
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67838
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94466
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14323
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.836313
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.929137
E2F4	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05205
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10509
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415283
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23807
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05691
hsa-miR-3174	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6681-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2855-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7562-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7409-01A-31R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4512
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20034
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052126
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-77-7141-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
pRb_Deficiency_GDS3176_605_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.428327
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858864
Lung adenocarcinoma_LUAD_TCGA-55-8506-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4-18268006-LS174T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50134
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59391
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828636
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE158834_10_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09606
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905088
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.6728
DDX47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02299
Brain Lower Grade Glioma_LGG_TCGA-DU-6408-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841701
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9709
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYK2_KD_GDS4754_158_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6917-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11062
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stomach_3a	HPA Tissue Sample Gene Expression Profiles	1.0	1.06063
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60619
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.746123
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76541
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.164786
GSE158834_10_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ESR1_ECC-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_splenic B cell_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92014
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896087
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85699
hsa-miR-3125	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PMC12882559-12894_2026_2046_MOESM2_ESM.docx-0-ZNF770_ZNF770	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF4-28076791-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49474
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.5877
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3681
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01519
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201043
ITPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33297
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909052
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941527
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47407
Lung squamous cell carcinoma_LUSC_TCGA-85-8277-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.53964
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53351
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20534
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11390959-41598_2024_70075_MOESM3_ESM.xlsx-520_DMD_common_down_gene_list-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate gland epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47495
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981418
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.443473
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29431
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04798
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040803
DA-20-VR86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.52948
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22469
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.837643
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04494
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.39918
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887179
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891996
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14637
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.831834
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17991
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.595705
celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.189859
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432553
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33702
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38014
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.982773
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_6479_OE_TWIST1_SRP341895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46821
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46372
TCF4	ChEA Transcription Factor Targets	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TUFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61073
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09801
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.12304
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213906
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44562
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.983419
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49265
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44562
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041018
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ICC106	DepMap CRISPR Gene Dependency	1.0	2.49317
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.55987
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897774
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00685
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.65595
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360379
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3717
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE201309_1_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27386
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hif2a_16565084_mcf7_lof_human_gpl2507_gds2761	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.33645
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
SUM185PE	DepMap CRISPR Gene Dependency	1.0	2.69854
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.63421
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LUDLU1_LUNG	CCLE Cell Line Proteomics	1.0	3.72405
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54953
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.794039
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.994571
Perturb_16508_OE_Rest_SRP314492	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09899
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67543
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22609
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28794
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841675
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.05341
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.87307
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Forodesine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
BB-42-FF52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414542
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960479
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54594
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01034
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919152
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00114
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07113
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22306
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67792
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25073
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350477
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.861636
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98505
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.652987
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11276
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7723_SDHAF1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.752125
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053809
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02084
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13936_KD_TTC8_SRP345436	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9538
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JHH7	DepMap CRISPR Gene Dependency	1.0	4.27708
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_12322_KD_BMAL1_SRP186908	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.9812
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
3554_GSPT1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.617654
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873396
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.58836
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29062
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.351613
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71151
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77952
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.05836
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39707
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86783
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.771979
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.27579
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9573
Perturb_285_KD_GPD1L_SRP303690	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1778
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.34997
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4312	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MDAMB468	CCLE Cell Line Gene CNV Profiles	1.0	1.77975
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.97531
ARX_KO_GSE12609_3_mouse_brain (subpallium, Pou3f-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24954
allergic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.225917
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292884
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46265
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91245
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.99111
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	1.0	1.43303
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8195-01A-31R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988124
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2756_KD_RBMS1_SRP254632	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.21214
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56527
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.885032
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.38182
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18071
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03433
HUCCT1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04594
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-2600-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042547
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00945
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347035
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01034
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937619
Perturb_3369_KO_Zc3h12a_SRP183512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.83663
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.519499
GSE203158_5_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28377
BC-80-FK74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204471
Prostate gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.809573
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13383
HMGA2_KO_GSE55340_21_mouse_lung (E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00562
NCIH2196	CCLE Cell Line Gene Expression Profiles	1.0	1.67571
Eye-adipocyte	Tabula Sapiens Gene-Cell Associations	1.0	2.08916
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
vagina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.490229
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36846
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.511483
MED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21627
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIPK2_overexpression_28_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.39881
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916739
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29S-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6075
10074-G5	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.531527
GABPA	ENCODE Transcription Factor Targets	1.0	null
10348_ZNF423_ENST00000262383.2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.546352
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845587
NC-52-AG88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393942
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A8-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43479
Lung squamous cell carcinoma_LUSC_TCGA-22-4595-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.80866
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852272
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42492
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7606-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.908126
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6628
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22677
EIF2S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35991
alpha-mannosidase activity	GO Molecular Function Annotations 2023	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227296
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11335
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_01_136	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.54647
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29136
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42567
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41197
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08365
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.970989
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0489
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.928499
GSE198165,GSE198166_0_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30294
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30416
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09659
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1765
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30719
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25017
SOX11	ChEA Transcription Factor Targets	1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945276
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.859441
TAF7	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928356
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS153	CCLE Cell Line Gene Expression Profiles	1.0	1.73048
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18895
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67332
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53883
measles	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.430768
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11723
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49612
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.926485
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241631
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8310-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055635
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27078
cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.513677
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.491627
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27714
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.968218
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34079
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88771
BORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18876
external encapsulating structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.481661
BE2M17	DepMap CRISPR Gene Dependency	1.0	4.83011
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63388
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12152148-41420_2025_2541_MOESM3_ESM.xlsx-AR-IP-DHT_peak-gene-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37343
BE-69-RD44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234469
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67517
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08261
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.91101
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3962
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827547
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954969
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_11_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54658
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862314
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90751
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.19195
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970202
GJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2347
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7636-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TARDBP_02_169	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64386
HMGN3	ENCODE Transcription Factor Targets	1.0	null
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22231
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02223
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878922
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835354
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888967
bj	HPA Cell Line Gene Expression Profiles	-1.0	-1.04944
Perturb_16507_OE_Rest_SRP314492	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56792
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61818
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385108
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38415
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053926
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73963
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07793
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE80537_0_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.931442
molaris	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416957
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NMB	DepMap CRISPR Gene Dependency	1.0	7.85302
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06089
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943594
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52072
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE132759_4_v_5_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72138
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_11_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41177
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_492_KO_LITATS1_SRP363523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05809
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62331
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979409
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849491
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4514	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1972
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26403
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.2623
HEY	DepMap CRISPR Gene Dependency	1.0	2.28091
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43977
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3922-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22051
nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174093
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	1.44535
congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.405305
hsa-miR-4704-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE158834_7_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0308
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47925
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06925
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
morphine_mus musculus_gpl6246_gse17731	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146982_0_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-36-VA24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373175
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT-483	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vorinostat_homo sapiens_gpl570_gse34880	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88606
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.568737
PPP6R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51843
PMC9314667-Table_1.xlsx-Regulons-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90805
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9084
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.825704
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-74-GP60_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324469
TCF12	ENCODE Transcription Factor Targets	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EV-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20I-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873511
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25236
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844533
JHH5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32654
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362825
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268417
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29602
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07038
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830287
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
KCNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.942
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19385
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941973
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19105
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.4058
MTF2	ChEA Transcription Factor Targets	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20106
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09996
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.903658
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
JW 480	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.46
Perturb_9447_KD_ESR2_SRP275562	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.44008
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03788
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95764
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.21561
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378901
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06098
RC-52-AC88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.417
ISL1-27105846-CHIP-SEQ-CPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0726
zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.432133
REST_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO668	CCLE Cell Line Gene Expression Profiles	1.0	1.62392
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.851216
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86867
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.927719
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
LRRC4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92304
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21401
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987089
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LAMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12274
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
UTP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20822
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34395
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05007
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203615
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.698386
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908252
EB-67-WB79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.542347
Perturb_15083_KD_Nsd1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.7773
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-42-FF52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201731
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2473
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42F-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56651
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF180_02_177	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60184
ESR1_T47D_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05738
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934233
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03219
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845587
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432631
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.161523
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5926
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.078981
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969354
AC-35-CK01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25165
6152_PDCD11_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.50038
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868034
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_12_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03785
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08291
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03161
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12459
HE-17-FY34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.560896
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PSMA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GD-46-BU97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.601742
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3620	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36185
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58788
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86754
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3784
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.093
REST_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12211
JUND_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-2.39936
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49829
TR146	DepMap CRISPR Gene Dependency	1.0	3.07976
RVH421_SKIN	CCLE Cell Line Proteomics	1.0	2.16726
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97479
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.50574
1578_CHML_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.618671
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.43588
Childhood acute lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
GE-77-FY84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.615108
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
REST_Panc1_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917677
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221772
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4373
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888967
BD-04-NG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.604986
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_9508_KO_Cd1d_ERP106455	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.08082
BLVRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10303
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50652
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841864
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2990-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874356
YAP1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.73718
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.78501
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.922716
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4365_KO_UTX/JMJD3_SRP158713	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867237
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90594
RCOR1	ENCODE Transcription Factor Targets	1.0	null
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74921
REST_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830287
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.998872
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2-25802403-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85819
DA-10-GX45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459866
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901451
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.543862
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96799
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47341
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PKMYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40652
Sarcoma_SARC_TCGA-DX-A48R-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00776
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.08601
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F7-01A-11R-A084-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942636
NCIH2122	CCLE Cell Line Gene Expression Profiles	1.0	2.10402
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21888
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.946307
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3936	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171572_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1314
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432115
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17317_KO_Ddx5_SRP284247	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.20314
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11354
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20933
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19515
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.826667
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RT112_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	2.23247
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.505954
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
7074_RAD54L2_ENST00000409535.2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.596967
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRP-0226-SM-3NB14	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885392
NCIH2106	CCLE Cell Line Gene Expression Profiles	1.0	1.46357
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
7516_RPS27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.17364
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923368
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202681
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JURLMK1	CCLE Cell Line Gene CNV Profiles	1.0	1.99522
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12268
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.10058
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.774355
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP3K7_knockdown_37_GDS5023	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52017
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05266
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RKN	DepMap CRISPR Gene Dependency	1.0	2.58919
CDK19_knockdown_162_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.52613
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993422
MCF7_Entacapone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0124822
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937342
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.917307
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH526	CCLE Cell Line Gene CNV Profiles	1.0	1.63018
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62438
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900249
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2863-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40811
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3194-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44153
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903506
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3153
GSE135350_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.82775
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914727
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213765
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37932
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE158834_11_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-SNU-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DSH1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.59386
rennet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.982386
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03744
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BE-13-XC52_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308156
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360625
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4677-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12700546-jci-135-197583-s034.xlsx-ST18-Unnamed_2_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28779
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61505
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOP1MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15735
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08338
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835671
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.39497
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.732058
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940801
SHI1	DepMap CRISPR Gene Dependency	1.0	2.56179
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1429
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62732
LRRFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61744
ARHGDIB_Transfection_GDS4455_551_human_UM-UC-3 bladder carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10921
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REST_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26565
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.70823
RCOR3	ChEA Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31613
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05007
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCC25	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49918
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.32583
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1708
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0135
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-PC-A5DO-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.976145
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01883
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.25043
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4111
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.398368
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_1_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE130401_6_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29977
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08682
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349945
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25797
SLC29A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05779
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42223
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5248-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K029AX_SKIN	CCLE Cell Line Proteomics	1.0	2.5971
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23032
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5981
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28409
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.69842
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990271
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03604
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.09155
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01142
NCIH510	CCLE Cell Line Gene Expression Profiles	1.0	3.27075
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.866471
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052806
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.80903
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826461
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14692
20081105-ST-2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856014
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
BD-69-GX17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286263
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47856
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29953
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-2.39672
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35475
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69241
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24844
A-Vietnam-1203-2004(H5N1)_18Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58565
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02681
747_BAG2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.63072
GSE130956_2_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02427
HDAC2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81995
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08652
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07733
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25238
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18524
thylakoid part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.512455
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57319
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28918
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904025
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86464
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.916608
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56734
SKRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-2.61266
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23098
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24197
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	1.68877
Perturb_3243_KD_UCA1_SRP124072	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963495
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.857277
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25583
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44239
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21788
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842523
GSE211286_4_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13863
VMRCLCD	CCLE Cell Line Gene Expression Profiles	1.0	2.07687
other organism part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.09866
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05334
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02055
hsa-miR-202	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
OELE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.54097
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00827
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05745
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4481	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04442
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16384
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.872487
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0112
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39949
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	5.55338
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1678
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.931238
A549_LUNG	CCLE Cell Line Proteomics	1.0	6.3084
GSE146982_0_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08113
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J7-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44433
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90319
GINS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31882
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25674
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73A-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FF-54-JC89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219774
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.425266
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.38982
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Duodenum disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5766
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-99-PN83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.441401
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYCN	ChEA Transcription Factor Targets	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56893
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14519
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34866
PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Unnamed_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.7317
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52784
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951437
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64997
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.83925
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1294	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40528
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31018
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074056
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.97447
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836734
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861916
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.32838
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.91202
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.047
SJSA1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58726
Sarcoma_SARC_TCGA-X6-A7WB-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30673
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSTZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22583
alpha-mannosidase activity	GO Molecular Function Annotations 2025	1.0	null
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	2.23569
Acute Myeloid Leukemia_LAML_TCGA-AB-2866-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5871_KD_Nudt21_SRP336206	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.38325
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.861885
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.828362
hsa-miR-4747-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01145
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53624
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11107
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936598
7505_RPS16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.509018
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
CHD2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895728
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06689
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.94889
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HMGA2_KO_GDS5048_26_mouse_embryonic lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09831
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39828
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891716
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27673
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00956
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.2765
Perturb_11572_KO_EPHB2_SRP388593	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.96219
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3368
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5677
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972945
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88228
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76998
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902751
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948159
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37287
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00392
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08438
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52865
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OD-96-OP94_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507243
GD-82-CS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.447522
CREB1	ChEA Transcription Factor Targets	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.993
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79038
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904256
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33336
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875376
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275137
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34628
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.004
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21452
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06115
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2345
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19298
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35984
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240439_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.28805
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.853748
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abomasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.159418
GSE139348,GSE139349_1_v_0_dicer1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13946
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33127
OVISE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Enzalutamide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
GSE210101,GSE210114_1_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05279
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54315
GATA3	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27379
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96443
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23869
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	2.70511
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.98092
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97726
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34309
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.30229
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.524803
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10562
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.009417
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.549408
HCC1833	CCLE Cell Line Gene Expression Profiles	1.0	1.98188
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10054
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78083
TRIP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84277
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07149
VC-19-YG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25153
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937625
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TF-77-DW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01821
Perturb_10836_KO_Per1/Per2_SRP194523	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.46076
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0293
host intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.192423
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849945
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02004
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4694-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
20081105-ST-1	GeneSigDB Published Gene Signatures	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985975
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum_8c	HPA Tissue Sample Gene Expression Profiles	1.0	0.856961
1633_CLASP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.500415
Perturb_6850_OE_ZNF37A_SRP273660	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.3979
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942832
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948526
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4519
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381038
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01449
COLO320	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73448
SUM229PE	DepMap CRISPR Gene Dependency	1.0	2.48076
2551_EIF3G_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.513122
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1081-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3154	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886917
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33165
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.561621
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A541-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.49332
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97581
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14585
NCIH1836	CCLE Cell Line Gene Expression Profiles	1.0	1.36601
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	1.73723
SLR25	CCLE Cell Line Gene Expression Profiles	-1.0	-2.34153
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH526	CCLE Cell Line Gene Expression Profiles	1.0	1.95501
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05007
PSMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2749
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00295
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.46047
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19694
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.429642
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52939
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2414
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250953
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.999044
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5555-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.903215
GSE80537_5_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.648476
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	1.49678
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2825
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11678
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251091
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14841
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24844
AD-66-NV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.630625
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13479
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30235
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90032
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930971
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.63546
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26113
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.74985
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.00241
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50825
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40885
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891317
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841892
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27976
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.265849
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040644
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.1896
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21686
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829438
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923787
RUNX3	ENCODE Transcription Factor Targets	1.0	null
E2F1	ENCODE Transcription Factor Targets	1.0	null
PSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88989
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08545
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14833
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_3_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0555
DA-19-JA87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.591882
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.637134
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F3_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
NB4	DepMap CRISPR Gene Dependency	1.0	2.68361
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845242
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34867
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_2_KD_HeLa-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03436
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.528989
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-Genes_with_ATF3_combined_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827443
Mesothelioma_MESO_TCGA-LK-A4O0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-2526-SM-4BOO4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954651
AE-04-SN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212984
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050818
AA-86-YY62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.570266
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59665
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90659
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03869
Proteasome activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
HS840T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60808
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50643
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900249
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204923
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXD9_01_70	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58933
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-211	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.834611
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.60008
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1258
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7076
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66022
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ4-2826-SM-3P617	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864147
NU 7026	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRCRCW	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81803
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.651777
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35727
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.72299
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE158834_11_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.958632
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16148
Dinoprost	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.6383
CHD1-26751641-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979797
HSPA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53997
occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38439
BE-28-WW67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216938
NCI-H720	COSMIC Cell Line Gene Mutation Profiles	1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.952648
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909401
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32087
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83187
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38232
CORL88	CCLE Cell Line Gene Expression Profiles	1.0	2.26616
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906166
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_2463_KD_RNF187_SRP334672	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04805
PSS008	DepMap CRISPR Gene Dependency	1.0	2.21854
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18821
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AB-30-CR11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664589
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.726929
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905852
HCoV-EMC2012_24Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.22335
KMRC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73106
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02109
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28863
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.504169
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7304190-13229_2020_355_MOESM18_ESM.xlsx-Supplemental_Table_5-hNSCs_SATB2_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.802589
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3974	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
placenta	HPA Tissue Gene Expression Profiles	-1.0	-1.01259
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05733
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate gland epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43275
EE-66-CK83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323455
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC8497275-41388_2021_1985_MOESM9_ESM.xlsx-ER_targets_ER-SRC3-RAC1_sites-Nearest_Ensembl_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BA-77-US35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.693719
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0528
exanthem	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.196459
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500934
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84143
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0474
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89596
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18034
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.603888
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5248
GTEx Thyroid 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.93667
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.908737
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.4328
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28049
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885231
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_1_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886655
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3145
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349715
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24844
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65921
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79067
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9637
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6752
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.26942
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08512
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.875722
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32746
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.94284
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998239
PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Table_S1_Lists_of_translational_targets_of_MYC_in_MYC_ON_vs_MYC_OFF_P493_cells_and_their_5_UTR_sequences_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
RNA polymerase II termination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892302
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50552
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESR1	ENCODE Transcription Factor Targets	1.0	null
HDAC6_KO_GSE27896_383_mouse_Foxp3+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888014
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.2046
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.7046
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.34109
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60538
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2919-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.78335
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.942427
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
HA-36-VD41_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228159
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44985
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992876
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07222
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317184
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-2.53907
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9327
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05632
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889741
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69659
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.41293
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870518
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05857
Leukocyte adhesion deficiency 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
DC-84-GJ21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221739
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337576
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79989
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
Sultiame	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.2
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12361
RAD21	ENCODE Transcription Factor Targets	1.0	null
Doramapimod	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1508
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79676
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01027
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.67
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851794
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38054
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3916	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
REST_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126517
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23682
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918476
PMC6941881-mmc4.xlsx-IR_only_down_DEGs-List_of_DEGs_that_are_downregulated_upon_PRMT5_KD_only_in_IR_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
BC-63-DM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.511258
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RA-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42045
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859714
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27579
ERCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18401
ChIP_ZFP281_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29988
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14053
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09002
ITFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13743
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14796
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.951337
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21901
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A703-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIM2	DepMap CRISPR Gene Dependency	1.0	2.11944
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286736
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5631-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11071
GSE163052,GSE163198_2_v_7_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05125
DE-34-DT75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.611492
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2BBE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89111
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34083
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.992776
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91589
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLUE1	DepMap CRISPR Gene Dependency	1.0	2.35572
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU5F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934937
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966998
ETS1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1752
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935909
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.779826
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914255
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17603561-STable1	GeneSigDB Published Gene Signatures	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040564
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21152
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5775
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976672
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04969
Perturb_3265_KO_Tet2_ERP013684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.3163
NB7	DepMap CRISPR Gene Dependency	1.0	3.34666
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17928
GSE169590_0_v_5_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867572
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTGES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14977
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08614
METTL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44323
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049925
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
REST	ChEA Transcription Factor Targets	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43121
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.89171
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042456
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.845124
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27177
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60808
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH209	CCLE Cell Line Gene Expression Profiles	1.0	1.9605
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36524
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221669
hMPV_24Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.15692
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0229
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31524
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.95196
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.965402
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977079
Ovary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.730727
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
EWS502	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65121
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.879405
KLF4	ChEA Transcription Factor Targets	1.0	null
SRSF9_02_134	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.66676
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985607
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12845
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3786
EGR1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.5696
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-10b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04873
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF154	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04594
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389887
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065007
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871619
HARA	DepMap CRISPR Gene Dependency	1.0	3.32252
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02349
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
hsa-miR-10a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048539
5888_NUP155_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.834716
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59047
RH-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.878793
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27841
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.75263
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32132
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4646-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
E2F7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10777
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87926
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5519-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985472
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888967
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2081	CCLE Cell Line Gene Expression Profiles	1.0	1.67648
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2606
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222311
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14481
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESR1-30970003-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
golgi apparatus part	GO Cellular Component Annotations 2015	1.0	null
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_1_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27819
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21535
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sitagliptin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.59
HCoV-EMC2012_3Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.13513
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93552
hsa-miR-3659	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
hsa-miR-1976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.79593
Sarcoma_SARC_TCGA-VT-A80J-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_2_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0986
TIG3TD	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97522
HDAC6_KO_GDS4375_372_mouse_CD4+CD25+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-71-8520-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7203
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SP1	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3661	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
hsa-miR-3065-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thp1	HPA Cell Line Gene Expression Profiles	-1.0	-0.82851
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.554663
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12831
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140651,GSE140653_3_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
QA-81-IM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410288
3788_HIST2H2BE_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.582189
hsa-miR-4745-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06511
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.19249
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.494156
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.94092
LIMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1164
TP53	ChEA Transcription Factor Targets	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CORL47	CCLE Cell Line Gene Expression Profiles	1.0	1.44575
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05173
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.61724
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03415
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23776
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.10459
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908059
Perturb_12658_KD_NFE2L2_SRP242008	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825072
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830287
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.86264
CREB1	ENCODE Transcription Factor Targets	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF12_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal recessive osteopetrosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051044
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3775
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tcf12_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.474906
SIMA	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14552
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Imiquimod	DeepCoverMOA Drug Mechanisms of Action	1.0	0.56
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898185
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Rivastigmine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.46
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914178
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XL-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXF289	CCLE Cell Line Gene CNV Profiles	1.0	1.58363
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS114_LUNG	CCLE Cell Line Proteomics	1.0	2.00914
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6853299-pbio.3000476.s011.xlsx-Fig_4A-RA_812_genes_expression_ratio_in_ZF_and_OF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37372
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34518
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40483
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32425
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02039
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51391
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	2.71142
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875935
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mannosidase activity	GO Molecular Function Annotations 2025	1.0	null
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51591
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89804
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38491
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830287
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33147
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84236
REST_01_337	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.75355
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18886
F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	4.20961
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399863
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28913
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.584303
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22435
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11445528-44318_2024_208_MOESM5_ESM.xlsx-AA-geneSymbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14656_KD_LINC00673_SRP102315	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
DLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5346
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71492
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26729
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158834_10_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418107
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28918
GSE239844_11_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02164
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65378
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00935
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.8467
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.476
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.84846
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875654
5927_OGDH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.727538
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC9A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49448
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.5597
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.43201
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4407
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1881
hsa-miR-631	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.91207
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08569
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-27a	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65536
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A6MB-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A50Z-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081497
GSE174701_5_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.369371
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
ESR1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63825
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69301
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06412
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7232-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.607047
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68633
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991937
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
BE-04-AN21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2959
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838255
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OB-17-DQ74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25186
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4692
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.60265
ME-16-XW76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.545745
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931506
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00935
GSE235066_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_Panc1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S0-EE-Y6Y9_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256304
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00935
hsa-miR-518d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051608
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153443_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.545857
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30071
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.486568
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042805
KU812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.51053
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.04517
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29345
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045324
Prostate adenocarcinoma_PRAD_TCGA-G9-6494-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
NCIH1092	DepMap CRISPR Gene Dependency	1.0	3.18616
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0518
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27631
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25138
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2262
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QS-01A-61R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SI-01A-31R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ascites	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.374993
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19029
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Poikiloderma with neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
hsa-miR-519c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MCF7_Roxadustat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0208222
Ascomycin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.38
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08277
Nigrostriatal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38307
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33134
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4234
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900753
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.99237
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.908184
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01205
REST_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34729
AF-30-GH67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249674
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063139
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15767
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10853
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03941
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01488
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31522
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0808
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21655
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1778
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407946
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.82944
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12856
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853568
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7107
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KTC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.918
KDM5A	ENCODE Transcription Factor Targets	1.0	null
BECKER	CCLE Cell Line Gene CNV Profiles	1.0	1.53681
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.941788
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
BRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02854
GSE158834_10_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CEP152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09932
colon_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.994611
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.425543
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2364
NRF1	ENCODE Transcription Factor Targets	1.0	null
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44363
GSE239844_4_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12866
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81956
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29351
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12625
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6826-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67332
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34672
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25266
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218171
USP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52277
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.991945
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.18474
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRIMPOL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07527
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72415
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04825
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00867
dentin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379875
CENPVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73532
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18505
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.718452
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58127
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41745
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51805
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973901
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048012
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_17045_KD_BATF3_SRP230607	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.8671
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.91556
Acute Myeloid Leukemia_LAML_TCGA-AB-3008-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Osteopoikilosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11147
GSE126463_6_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889284
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042471
periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.696172
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.88797
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.90897
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A718-01A-22R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU668	DepMap CRISPR Gene Dependency	1.0	2.31594
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875172
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.38947
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07693
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26464
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02711
GSE197532,GSE197533_0_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96816
BCX 1470	DeepCoverMOA Drug Mechanisms of Action	1.0	0.39
ESR1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985439
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47253
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CACNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38112
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71579
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4-18268006-LS174T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POR_KO_GDS1349_497_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55616
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.854532
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044969
RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE204811,GSE204813_1_v_3_trim29_human	RummaGEO Gene Perturbation Signatures	1.0	null
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337135
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.934253
AP3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65996
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.624346
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878423
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65161
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948526
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.8854
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58024
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.583728
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01951
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	3.03353
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72621
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03907
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329772
LUDLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33468
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444033
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38923
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.88633
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51774
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212413
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.545299
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57314
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32123
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.253
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.97892
FAM53C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1434
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07383
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12879
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.14924
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.742204
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43638
DLX5_OE_GDS4577_345_mouse_Otic vesicle derived 2B1 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941525
superior parietal lobule, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.924322
EGR4_01_132	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64063
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34494
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18594
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0511
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GD-82-CS38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249145
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G43417UB	GlyGen Glycosylated Proteins	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85414
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38296
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.3044
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5783
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29017
POLR2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30044
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.97188
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46496
cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159124
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33123
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04916
PMC6766969-PATH-249-90-s005.xlsx-S1_b-Supplementary_Table_S1_b_Top_100_upregulated_and_downregulated_genes_in_TAF15-NR4A3_vs_EWSR1-NR4A3_EMC_NR4A3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140937,GSE140938_1_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
4593_LIN52_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.507574
Acenaphthoquinone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078706
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91449
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7367-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.71064
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.20872
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8265
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19236
JA-26-YQ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.669773
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.766508
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.485487
NB-12-ZK38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293246
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70844
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902785
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067928
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MK-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPSF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39563
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15339
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.316
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10583
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZFP281-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.69584
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51532
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64366
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15370_KD_TP53_SRP294453	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMIM10L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48101
myb_16205643_primary_monocytes_gof_human_gpl570_gse2816	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.875405
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
OAW-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REST_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02648
GSE182854_2_v_3_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03036
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.90239
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204193
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39368
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22055
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB3A_Mutation - D77G point mutation_GDS2483_697_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06794
Melorheostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMRC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68486
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23157
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.826
NCIH1184	CCLE Cell Line Gene CNV Profiles	1.0	2.20946
GSE158834_1_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52473
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72829
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0858
GSE209973_1_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE159049_3_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-61	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_13851_KO_RET_ERP126468	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7210-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264195
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.7191
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.963135
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0654
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.1032
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03565
KASUMI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LKB1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3163
DOV13	DepMap CRISPR Gene Dependency	1.0	2.73437
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PJ34	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Osteosclerotic metaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
RH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1732
RIOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03279
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.001426
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62757
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14625
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44251
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14952
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRAPPC6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37988
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03248
BACH1	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16639
4593_LIN52_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.504445
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34004
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03525
GTEX-PWCY-1926-SM-3NB25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961623
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40798
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21821
ESR1_T47D_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836764
NH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86609
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843245
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.95204
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75237
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3Q8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39708
ZBTB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0909
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00935
REST_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WC-09-GD62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297024
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46184
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60124
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06833
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16338
REST_01_338	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.12129
SKES1_BONE	CCLE Cell Line Proteomics	1.0	5.47475
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01167
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06328
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Buschke-Ollendorff syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
KMS11	DepMap CRISPR Gene Dependency	1.0	2.12307
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05007
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.59214
PMC2813300-pone.0008960.s011.xls-SOX2_squamous_signature-Gene_Symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460187
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.616221
CCNO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94906
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Premature aging_Skin fibroblast_GSE10123	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.19427
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE126463_1_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825072
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03374
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A185-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948526
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3924
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
WC-33-YP46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222064
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cerebral peduncle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.304
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_up-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.959759
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.882797
5726_NOB1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.62519
GTEX-TKQ1-0226-SM-33HB5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959115
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05007
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877109
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10398
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreas-pancreatic alpha cell	Tabula Sapiens Gene-Cell Associations	1.0	0.170874
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17016
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.531592
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
WFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3688
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31918
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44412
GSE131680_1_v_0_macroh2a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.3061
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34554
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.524942
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1271_LUNG	CCLE Cell Line Proteomics	1.0	2.2258
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86024
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60981
KU812	DepMap CRISPR Gene Dependency	1.0	8.23435
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.665163
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3984
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21925
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31875
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09009
E2F4	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34341
PMC12823428-43587_2025_1018_MOESM3_ESM.xlsx-ST12-Supplementary_Table_12_Main_mendelian_randomisation_results_of_plasma_proteins_on_delirium_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21886
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52053
Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16293578-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066215
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54461
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22222
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07453
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83227
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54909
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.55152
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11661
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907888
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4128
PAX6	ChEA Transcription Factor Targets	1.0	null
thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.498636
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.995879
HS739T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55384
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.894121
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02413
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_NACC1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348519
Duodenum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.82944
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
PMC12826982-mmc5.xlsx-Table_S4-Supplementary_Table_S4_Differentially_Bound_Down-regulated_Peak-Related_Genes_in_Flag-SOX3-HSV-1_vs_Flag-SOX3-Mock_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056663
GTEx Thyroid 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	7.05104
PANC1005	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43075
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79129
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19255
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892655
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.27476
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNB19_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.20205
JRA - Juvenile rheumatoid arthritis_Peripheral blood mononuclear cell_GSE7753	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.37341
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02742
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07909
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.0057
SUZ12	ENCODE Transcription Factor Targets	1.0	null
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1343
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y0-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995122
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36333
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.952807
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05007
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3179	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1987
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.883451
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOTO	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46882
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.796192
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42905
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88757
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2029	CCLE Cell Line Gene Expression Profiles	1.0	1.73321
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-2355-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1415
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89211
CX3CL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00015
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64595
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.81905
NDUFB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81501
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113952,GSE113953_1_v_0_chtop_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953531
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOS1	DepMap CRISPR Gene Dependency	1.0	4.78049
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.641615
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.40327
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24844
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49644
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.596664
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
OV7	DepMap CRISPR Gene Dependency	1.0	3.10521
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.479356
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.49648
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10026
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.27226
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.09681
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045496
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-2.75643
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.755662
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.854997
IALM	CCLE Cell Line Gene CNV Profiles	1.0	1.43677
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ECGI10	DepMap CRISPR Gene Dependency	1.0	3.04613
klf7_17123745_olfactory_epithelium_lof_mouse_gpl1261_gds2069	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.380485
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27156
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.20081
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943347
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36332
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05528
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.909007
Perturb_62_KD_Ccnt2_SRP312148	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.25272
biological_process	GO Biological Process Annotations 2015	1.0	null
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.31142
CLNS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08206
D283MED	DepMap CRISPR Gene Dependency	1.0	3.62712
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03309
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1793	DepMap CRISPR Gene Dependency	1.0	2.01864
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59108
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24876
9686_UTP3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.510105
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61859
hsa-miR-4678	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
GSE147240_0_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.64916
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.768528
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.75
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03419
GSE206784_3_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82922
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV5-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HB1119	DepMap CRISPR Gene Dependency	1.0	2.31019
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834854
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47001
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268828
golgi membrane	GO Cellular Component Annotations 2015	1.0	null
CSE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80969
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.94347
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH810	CCLE Cell Line Gene Expression Profiles	1.0	1.48094
CC-84-JQ48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.473971
GSE181513_0_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888885
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.30619
hsa-miR-580	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.889558
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.676921
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61969
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06824
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33956
increased mean corpuscular hemoglobin	MGI Mouse Phenotype Associations 2023	1.0	null
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.21786
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-548o	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860614
EPZ-6438	DeepCoverMOA Drug Mechanisms of Action	1.0	0.52
Perturb_12218_KD_EPRS_SRP073504	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76252
SAOS2_BONE	CCLE Cell Line Proteomics	1.0	2.87713
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90906
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848382
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55914
tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.522405
Hemoglobinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
QA-34-PH05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235647
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21573
G401_SOFT_TISSUE	CCLE Cell Line Proteomics	1.0	2.25598
G292CLONEA141B1	DepMap CRISPR Gene Dependency	1.0	2.20307
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_10_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	2.56511
Lung adenocarcinoma_LUAD_TCGA-44-6779-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990282
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.5786
visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476979
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61455
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COV504	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51451
17638893-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32999
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21574
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.8805
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29484
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58884
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52284
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054974
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825072
Perturb_4737_KD_Fto_SRP061617	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.52504
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.992346
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NACC1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39032
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965759
GSE182680,GSE182683_10_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41277
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72974
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0175
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34738
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84528
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.771643
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Diabetes Mellitus	CTD Gene-Disease Associations	1.0	1.03419
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70825
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892302
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12247
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.9025
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.567361
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03311
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35793
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00935
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2886
WARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17726
edwards syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.704742
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37292
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ESR1-20056654-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	154.882
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23313
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE200839,GSE233826_5_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042513
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17692
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07161
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.36883
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14126
TAL1	MotifMap Predicted Transcription Factor Targets	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.73891
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JK-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00518
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-42-YI34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267041
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54H-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUDHL4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	5.24391
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28423
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238241
Perturb_13904_KD_UNK_ERP004682	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.64906
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.912905
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36363
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36946
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04374
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837407
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886557
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5347
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202956
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.03752
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934239
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.792
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978767
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73594
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92014
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86887
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3_01_84	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60276
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04444
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	1.44064
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923336
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KASUMI1	DepMap CRISPR Gene Dependency	1.0	4.57543
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.970467
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.47491
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10005
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.999958
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13232
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04225
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946723
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849389
YAMATO	DepMap CRISPR Gene Dependency	1.0	4.92095
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825494
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960785
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41228
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.90321
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24635
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.886051
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52431
Lung adenocarcinoma_LUAD_TCGA-95-8039-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46326
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.7445
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44223
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.72037
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.2596
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REEP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77744
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.863319
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1778
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955924
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448765
Sarcoma_SARC_TCGA-WK-A8XY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.386463
MCM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49789
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97068
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237636
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06245
hsa-miR-526a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048125
SKGT2	DepMap CRISPR Gene Dependency	1.0	2.94913
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LC-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19556
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01861
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-7268-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34218
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ECGI10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76765
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.6492
BCL2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03467
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10185
8405_SRFBP1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.515154
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02095
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09959
BD 1008	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.27
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12622
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32999
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.935725
IB-33-TE51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352425
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43026
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204923
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56245
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350502
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.479
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
adipose tissue	GTEx Tissue Gene Expression Profiles	-1.0	-0.935269
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25297
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055391
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OTT1_KO_GDS4315_146_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
LF-94-HB11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297685
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR16	DepMap CRISPR Gene Dependency	1.0	2.49992
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11338
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37948
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19312
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.667552
HDAC6_KO_GDS4375_532_mouse_Foxp3(+) Tregs	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93753
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.577292
TAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13045
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917372
DC-45-WU45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202415
ESR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6339
NR4A2	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48149
SUM159PT	DepMap CRISPR Gene Dependency	1.0	3.94396
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0148
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1427
TTC21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19014
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83629
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912561
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2711
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-6546-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173232_2_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLR20	DepMap CRISPR Gene Dependency	1.0	2.39654
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_filtered-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58189
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112760,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041319
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17824
PMC3518872__F3	PFOCR Pathway Figure Associations 2024	1.0	null
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947315
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.25836
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NB17	DepMap CRISPR Gene Dependency	1.0	4.95697
Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TYKNU	CCLE Cell Line Gene CNV Profiles	1.0	1.3389
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90211
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7935
MHHES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50492
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.966
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26681
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25577
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.866015
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ADAMTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10322
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_4_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.0764
Golgi trans cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921438
KNS42	DepMap CRISPR Gene Dependency	1.0	3.2286
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.956795
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.56163
GSE178714_5_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.544912
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955834
GNE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47672
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_DPPA5A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69467
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
Wolf-Hirschhorn syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23286
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825072
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22279
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ChIP_POU5F1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71485
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4501
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16501
OB-06-WW76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.556895
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16611
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46432
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03858
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289117
small intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.637495
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38371
skbr3	HPA Cell Line Gene Expression Profiles	-1.0	-1.4544
PBX1	ChEA Transcription Factor Targets	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925249
PMC11956947-media-4.xlsx-C_GSEA_gene_sets-TGAYRTCA_ATF3_Q6_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93558
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51197
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.89858
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071437
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51381
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE109285_3_v_4_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20351
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.518981
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85123
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05219
gingiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235167
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.63985
ESR1_T47D_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877627
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.96578
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873217
PANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36006
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
[Pyr1]-Apelin-13	DeepCoverMOA Drug Mechanisms of Action	1.0	0.43
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6016
Sarcoma_SARC_TCGA-HS-A5N7-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100641_PCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01082
tamoxifen_homo sapiens_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11927
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
Eyebrow thickness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE80537_3_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.2481
Neurodegeneration with brain iron accumulation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
FUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5141
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02811
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
OVCA420	DepMap CRISPR Gene Dependency	1.0	3.36186
GSE203158_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU46	DepMap CRISPR Gene Dependency	1.0	4.33683
16273092-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35301
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900249
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.849551
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2399
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8221
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912444
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01907
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044256
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63986
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16804
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229580_2_v_1_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040673
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02983
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41305
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-128	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.719118
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54449
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.970093
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A-Vietnam-1203-2004(H5N1)_12Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.78203
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_1_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39964
MAP4K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36521
J82	DepMap CRISPR Gene Dependency	1.0	2.68997
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL24	CCLE Cell Line Gene CNV Profiles	1.0	2.67546
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26949
ANKFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74456
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60933
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971732
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.952648
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2144
mannosidase activity	GO Molecular Function Annotations 2023	1.0	null
ZNF281	ChEA Transcription Factor Targets	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10693
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GK_KO_GDS1555_127_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
IGR39_SKIN	CCLE Cell Line Proteomics	1.0	2.26266
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IF-31-RN78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.577323
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269723
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06096
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-519b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08116
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876026
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29X-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28792
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HR-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.49143
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.731179
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871828
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.951337
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336838
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.481194
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0399
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
viral replication complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.192423
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09373
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2967
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.871144
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1641
ATP6V0E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02748
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16263
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13288
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.951786
periodontal ligament	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.697399
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.687765
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09304
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980087
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05899
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35916
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92253
Prostate adenocarcinoma_PRAD_TCGA-HC-7077-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053124
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56002
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTPBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21053
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09756
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.640691
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30433
WC-95-BX35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233579
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74635
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35605
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5799
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21807
host cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.137817
UNC45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22919
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48151
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.18955
PAX5	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32664
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34757
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4305
KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19636
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51792
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22323
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ER-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06035
CACO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57169
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115328_6_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09696
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2973
prostate gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HEC116	DepMap CRISPR Gene Dependency	1.0	2.39513
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878787
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_1_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9625
RFX5	ENCODE Transcription Factor Targets	1.0	null
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042191
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.830291
GSE209698_0_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183606_1_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8497275-41388_2021_1985_MOESM9_ESM.xlsx-ER_targets_ER-SRC3-RAC1_sites-Gene_Name_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CPNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50773
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.989242
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48701
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881054
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45661
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	4.09992
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.88613
neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230382
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A953-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE229468,GSE229471_0_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6712-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2122	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32999
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957023
ZEB1	ENCODE Transcription Factor Targets	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.42956
GSE242290_1_v_7_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.819125
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11841
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SL-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4783
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01034
GSE119498_2_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LS1034	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37338
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE62843,GSE64370_4_v_1_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
REST_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849034
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.236
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.64415
NDUFA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66123
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68362
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DD-26-RY82_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216709
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69648
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77435
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29438
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7783
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12766
GSE210101,GSE210114_4_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1637
LY6E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03186
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455982
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841199
GSE242290_1_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65388
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6773
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825072
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35593
GSE147240_3_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832861
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917633
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12546
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.950478
hsa-miR-4692	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.37196
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10868
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986807
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12703
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22082
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08524
PPP1R13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44994
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.8983
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.932517
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856408
4926_MEAF6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.599552
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847623
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825072
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.87281
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04187
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05548
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6588
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
duodenum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.70434
VPC23019	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213688
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Perturb_2984_Mut_TP53_SRP287851	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.48769
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.202618
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.81645
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93305
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925579
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1323	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.53383
fat_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.867532
deltaEF1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59042
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-ATF3_TGAYRTCA_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.97316
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20766
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903344
NCIH2122	CCLE Cell Line Gene CNV Profiles	1.0	2.37909
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	3.4174
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.4281
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49949
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853666
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23998
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_7_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	2.38332
FBRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22285
autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.136794
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49145
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33016
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954996
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
9587_UMPS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.6695
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8319
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
host cell nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.192423
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00042
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REST_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36094
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46891
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129354
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2188
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51219
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AQP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1502
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857454
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26025
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46229
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06357
GSE229468,GSE229471_2_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_3901_KD_CTNNB1_SRP314475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S7-Table_S7_Top_500_differentially_modified_gene_bodies_between_MM_and_its_precursors_in_AA_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.70188
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240027,GSE240030_5_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.20397
SYK_druginhibition_282_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.76132
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.05973
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32822
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Golgi lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.161
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TB-06-VB30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.479495
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09829
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32277
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.5566
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05737
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.977608
CORL279	CCLE Cell Line Gene Expression Profiles	1.0	1.35201
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.9944
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.881853
Osteosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.970286
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21673
NCIH2029	CCLE Cell Line Gene CNV Profiles	1.0	2.09041
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	5.55052
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2347
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9184
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3639
hsa-miR-4257	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.55931
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862849
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52302
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.63523
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6924
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.534706
WM793_SKIN	CCLE Cell Line Proteomics	1.0	2.20205
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.02225
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932167
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_2_KD_HeLa-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELF3-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2473
MyoD	MotifMap Predicted Transcription Factor Targets	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.983485
SYK_druginhibition_285_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.1665
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_Panc1_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.667049
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39096
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963167
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36071
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.513091
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71154
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81381
hsa-miR-1292	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4837-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4331
TRPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00807
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14979
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924624
DCUN1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93593
GSE207301,GSE207303_0_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54953
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.843185
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06787
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41277
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968361
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.889127
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.089744
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.57851
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
6152_PDCD11_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.510145
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906298
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.68408
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1778
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-520c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02288
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.95834
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058084
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.684327
YY1	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.446
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825972
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222246
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8175-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.41438
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.832879
Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BA-52-FW03_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225176
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19361
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	2.7489
Perturb_12970_KO_PRMT7_SRP342313	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.71848