association	dataset	threshold value	standardized value
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34493
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.736331
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882983
Lung adenocarcinoma_LUAD_TCGA-05-4249-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQ7-0826-SM-447B3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10372
Berzosertib	DeepCoverMOA Drug Mechanisms of Action	1.0	2.45
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.51042
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60959
HAT1	Pathway Commons Protein-Protein Interactions	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215579
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03994
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.15516
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.881079
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.26731
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4743
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096806
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42306
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75365
FF-90-JK74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.691255
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.926821
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105736
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206474
ZNF843	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17795
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75439
ubiquitin protein ligase binding	GO Molecular Function Annotations 2025	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0869
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.935238
ED-81-ZH14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236174
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.132328
HE-16-PO98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243617
SMI-16a	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABL1_druginhibition_77_GSE24493	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.40702
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58179
Pt-K1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ammonium transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05432
GTEx Heart 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-3.65988
GTEX-VJYA-1226-SM-3GIJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25357
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15429
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051636
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30468
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67431
IKZF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-1126-SM-4JBHT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02821
GTEX-XYKS-1026-SM-4BRVH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31948
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906858
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909049
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868923
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20637
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cellular response to starvation	GO Biological Process Annotations 2025	1.0	null
RELA_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3513
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.035312
Sarcoma_SARC_TCGA-QQ-A5VB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATG5	Pathway Commons Protein-Protein Interactions	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902697
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W7-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21936
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33826
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.861149
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.385205
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4133-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.15983
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-0926-SM-48FDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969792
response to starvation	GO Biological Process Annotations 2015	1.0	null
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864085
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-3398-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55703
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06491
arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163938
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22033
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.36512
tubulin binding	GO Molecular Function Annotations 2025	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.888043
NRK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.18923
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.408986
RNF2	ENCODE Transcription Factor Targets	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3157
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65432
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4945
MTA3	ENCODE Transcription Factor Targets	1.0	null
acute lymphocytic leukemia	GWASdb SNP-Disease Associations	1.0	1.32598
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94182
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26768
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21201
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26628
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936448
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.708594
Ruboxistaurin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.89
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02966
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.00001
EW16	DepMap CRISPR Gene Dependency	1.0	5.72981
cytosol	GO Cellular Component Annotations 2015	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.15429
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04756
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37622
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.32701
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210578
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00262
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53369
NB-12-ZK38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216813
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.42699
response to nutrient levels	GO Biological Process Annotations 2015	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909197
all	GWASdb SNP-Phenotype Associations	1.0	0.035217
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874155
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92769
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.158201
AE-32-DP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217707
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906858
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.36301
Phagophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.887
GTEX-SNMC-1126-SM-4DM5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03886
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959992
TB-06-VB30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298266
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04161
CEBPB_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-24-AT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33876
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07137
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.83999
lymphoblastic leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.414708
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKNFI	CCLE Cell Line Gene CNV Profiles	1.0	1.5177
AB-97-BI36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224822
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29103
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XM-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-02-RV60_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311879
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.91602
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75799
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77203
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31315
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226184
GA-59-RW04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.468687
MLN 8237	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
SH4_SKIN	CCLE Cell Line Proteomics	1.0	3.30249
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10287
REST	ENCODE Transcription Factor Targets	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.93826
OB-06-WW76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.587213
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
GE-29-ZM45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309132
Cerebral peduncle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.085
QF-00-NO42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224843
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7771094-12920_2020_832_MOESM5_ESM.txt--ATF2_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.647373
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058706
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.9499
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.86464
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
WB-82-EL69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284475
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1937_BREAST	CCLE Cell Line Proteomics	1.0	2.50136
skin	HPA Tissue Gene Expression Profiles	-1.0	-0.87047
Vascular cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83059
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44551
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
leukemia	GWASdb SNP-Disease Associations	1.0	0.463687
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840757
brain	HPA Tissue Gene Expression Profiles	1.0	0.940036
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56477
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.482011
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963396
A172	DepMap CRISPR Gene Dependency	1.0	3.9666
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05147
PMC8688647__F3	PFOCR Pathway Figure Associations 2024	1.0	null
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.381878
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleoplasm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053403
POU2F2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28721
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33693
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7647-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06023
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-XMK1-1326-SM-4B65Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952135
cellular response to nitrogen levels	GO Biological Process Annotations 2025	1.0	null
organelle disassembly	GO Biological Process Annotations 2015	1.0	null
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55447
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2489
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	4.67089
thp1	HPA Cell Line Gene Expression Profiles	-1.0	-1.3912
Fingolimod	DeepCoverMOA Drug Mechanisms of Action	1.0	0.69
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4174-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5909
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977295
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.650225
Lung squamous cell carcinoma_LUSC_TCGA-60-2696-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05575
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Saracatinib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.72
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879882
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42C-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18368
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879625
lateral ventricle	HPA Tissue Protein Expression Profiles	1.0	0.929301
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07559
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.692826
CCNT2	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08461
GTEX-QLQW-0626-SM-447A6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20495
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.72032
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74562
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.920798
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4726-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.45544
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61269
EPB41L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24232
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64516
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1839
IALM_LUNG	CCLE Cell Line Proteomics	1.0	2.58066
GTEX-REY6-2426-SM-48FF5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958972
congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.70233
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5843
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85813
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857009
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.40619
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28982
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-8500-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK4	Pathway Commons Protein-Protein Interactions	1.0	null
PAX5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063641
JD-62-HR05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203258
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242608
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.759957
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.810229
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.42655
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247175
SPINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30244
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26707
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04583
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830643
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ferroptosis	KEGG Pathways 2026	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0981
MAP1LC3B	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE70	DepMap CRISPR Gene Dependency	1.0	2.11898
cellular response to external stimulus	GO Biological Process Annotations 2015	1.0	null
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42539
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00973
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01609
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
ATG3	Pathway Commons Protein-Protein Interactions	1.0	null
Hyper IgE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2008
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041966
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100343_TCx_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10045
Sarcoma_SARC_TCGA-DX-A3LS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898704
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296745
CREB1_01_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.27691
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08238
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949704
Leaf tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266689
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28673
GTEX-WFON-0626-SM-4LVLX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903089
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.752769
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5303-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49139
GTEX-V955-0326-SM-4JBGV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63936
ZNF526	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25164
KAT2B	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25342
GATA1_erythroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.041983
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33776
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.13203
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03118
RA-49-ZB08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440057
NKX1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01353
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73626
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.586902
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DT-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80939
MAX	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00873
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.48138
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953508
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4024
SA-53-XG95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311819
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CB-87-RB49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.398674
EP300_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248544
Acute Myeloid Leukemia_LAML_TCGA-AB-2888-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969934
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78478
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
STK410281	DeepCoverMOA Drug Mechanisms of Action	1.0	1.07
MYC	ENCODE Transcription Factor Targets	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
DE-69-QQ25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.618639
RTEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54546
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.459561
MAFF	ENCODE Transcription Factor Targets	1.0	null
KMS11_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	9.28673
HAUS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77891
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.35989
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043361
d17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79577
Lung adenocarcinoma_LUAD_TCGA-80-5611-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mcf-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331194
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
EMTOKA	DepMap CRISPR Gene Dependency	1.0	2.25872
STAT5A	ENCODE Transcription Factor Targets	1.0	null
HPAFII	CCLE Cell Line Gene CNV Profiles	1.0	1.73583
Protein storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.33784
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSU	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63063
Erythroid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.348
Tetrindole	DeepCoverMOA Drug Mechanisms of Action	1.0	0.97
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13675
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.66154
hsa-miR-4429	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BCS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86374
MYC_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448717
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16285
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6725
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29081
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.70563
RAD21_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.414708
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9008
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945939
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.725782
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898704
Leaf epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
ZNF143	ENCODE Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053957
GSK-1070916	DeepCoverMOA Drug Mechanisms of Action	1.0	2.37
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AE-19-BK71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29903
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31036
DA-17-YW85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202394
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
GTF2B	ENCODE Transcription Factor Targets	1.0	null
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0263
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31164
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341495
GTEX-NFK9-2026-SM-3LK5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833106
Hepatic venoocclusive disease with immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.902551
u87	HPA Cell Line Gene Expression Profiles	1.0	1.13699
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.57711
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06932
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34034
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2795	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63158
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50188
Respiratory epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.252
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26443
KDM5B	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12712
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.828011
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06651
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954523
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061635
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928841
BICR10	DepMap CRISPR Gene Dependency	1.0	4.00207
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34305
organelle assembly	GO Biological Process Annotations 2025	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.931486
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77232
Sarcoma_SARC_TCGA-DX-A7EF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3014
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17507
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1812
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.975994
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43669
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58323
EHEB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825308
RCM1	DepMap CRISPR Gene Dependency	1.0	5.7763
ZB-33-MZ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24299
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16204
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00699
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10569
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894008
Phosphatidylinositol 3-kinase complex, class III, type I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226797
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.685146
cellular component disassembly	GO Biological Process Annotations 2015	1.0	null
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23853
PMC12529848-12967_2025_7217_MOESM3_ESM.xlsx-Table_S4-Table_S4_Associations_of_genetically_proxied_proteins_with_risk_of_atrial_fibrillation_by_MR-SPI_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CH5132799	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.08
ITPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13366
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968836
phosphatidylethanolamine binding	GO Molecular Function Annotations 2025	1.0	null
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874451
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.524423
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.746359
Phagophore assembly site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.468
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.99928
HMEC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_A-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.395402
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22097
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.83022
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
PC3_PROSTATE	CCLE Cell Line Proteomics	1.0	2.46962
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02603
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
leukemia, lymphoid	GAD Gene-Disease Associations	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56097
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64534
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.34312
TCF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51783
PMC10794847-mmc3.xlsx-PBRM1_KD_down-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JF-55-EN33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209995
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.28828
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072437
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.05278
RFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07235
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE146840,GSE146842_3_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	1.0	null
autophagosome organization	GO Biological Process Annotations 2025	1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.809708
FA-80-DR66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.702783
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KLHL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54109
RELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05918
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.754187
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04932
F5	DepMap CRISPR Gene Dependency	1.0	3.67559
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.717895
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-81-DL34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.445867
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.27159
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2851
ZNF778	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07403
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KU 55933	DeepCoverMOA Drug Mechanisms of Action	1.0	0.39
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2517
Membrane fusion priming complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.32
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27832
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vacuolar lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
Adrenocortical carcinoma_ACC_TCGA-OR-A5JF-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040223
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24941
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.77339
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926508
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32609
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.0366
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848163
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26628
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3038
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-5775-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.888918
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.552993
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
LU99	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849061
u26684	HPA Cell Line Gene Expression Profiles	1.0	0.843122
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
ROS50	DepMap CRISPR Gene Dependency	1.0	3.89666
vacuolar membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23637
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845524
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969934
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02525
Fibre tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.085
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.42036
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0994
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4389
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-32-DP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203325
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38031
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360998
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RN486	DeepCoverMOA Drug Mechanisms of Action	1.0	1.61
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845271
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.82945
PMC11043338-41523_2024_637_MOESM1_ESM.pdf-133-DDIT3_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.556983
GTEX-OXRK-1626-SM-3NB17	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15862
GTEX-P78B-1026-SM-3NMC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06398
GATA2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD-92-QT24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486756
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857685
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066442
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.37848
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.845425
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914645
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37064
NF-21-HQ00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238348
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.63986
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.61048
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular response to nitrogen levels	GO Biological Process Annotations 2023	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.07291
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.83768
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Apelin signaling pathway	KEGG Pathways 2026	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.929301
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.8078
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.292717
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.542862
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215732
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0994
GTEX-X8HC-1526-SM-46MWD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965424
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38243
TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3706
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein-containing complex disassembly	GO Biological Process Annotations 2025	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166783_4_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematological neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.239156
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0329
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1346
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-4777-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256866
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46916
cytoplasmic vesicle	GO Cellular Component Annotations 2015	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Untreated-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
KP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39096
CEBPB_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GLYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25764
MAP1B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.31886
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35696
Right_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.870344
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17776
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77444
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.363063
RB-34-TO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.382191
GTEX-V1D1-1226-SM-4JBI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855744
RXRA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73533
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bafilomycin A1	DeepCoverMOA Drug Mechanisms of Action	1.0	2.25
Avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.29
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.466548
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.178878
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE149760_3_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MA-43-MR37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.575522
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Marrow cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
Leukemia, Lymphoid	dbGAP Gene-Trait Associations	1.0	0.660359
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20245
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
single-organism catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8462
NDUFA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68369
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938281
MVB12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20147
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05266
CAMSAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06243
IRF4	ENCODE Transcription Factor Targets	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DG-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08607
TMEM160	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931369
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.03656
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47924
MEF2C	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905153
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-01A-31R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.85329
GD-46-BU97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217983
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03657
autophagosome	GO Cellular Component Annotations 2023	1.0	null
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2669
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054734
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7822-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14864
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20924
Mesothelioma_MESO_TCGA-LK-A4O2-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-2326-SM-47JYR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02119
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91683
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257874
MK2206	DeepCoverMOA Drug Mechanisms of Action	1.0	1.12
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.598733
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5178
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92673
TP63	ChEA Transcription Factor Targets	1.0	null
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S0-EE-WH3B_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235387
autophagy of mitochondrion	GO Biological Process Annotations 2025	1.0	null
hsa-miR-4676-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34792
NOD-like receptor signaling pathway	KEGG Pathways 2026	1.0	null
Shigellosis	KEGG Pathways 2026	1.0	null
Nrf-2	MotifMap Predicted Transcription Factor Targets	1.0	null
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25017
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831704
PD-26-DC63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202579
Pictilisib	DeepCoverMOA Drug Mechanisms of Action	1.0	1.09
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZR751_BREAST	CCLE Cell Line Proteomics	1.0	2.58066
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6954-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular response to nitrogen levels	GO Biological Process Annotations 2015	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02589
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular response to nitrogen starvation	GO Biological Process Annotations 2015	1.0	null
Fine root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.717
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17241
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07234
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lapatinib	DeepCoverMOA Drug Mechanisms of Action	1.0	2.26
Tozasertib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.87
LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
AD-86-OB87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312799
Parenchyma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.051
Cediranib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.91
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15183
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848163
4-Nitropiazthiole	DeepCoverMOA Drug Mechanisms of Action	1.0	0.5
Root apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949279
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068925
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7651-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.414708
acute leukemia	GWASdb SNP-Disease Associations	1.0	1.32598
EC-82-LV30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.387542
Tandutinib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.67
PMC4487811-mmc3.xlsx-siRE_enriched_geneLists-siRE_occupancy_pattern_gene_lists_after_RUNX1_ETO_knock_down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAFB2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86625
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38885
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NP3	DepMap CRISPR Gene Dependency	1.0	2.61591
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36027
CC-68-YZ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.491721
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13862
ATP6V0D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11551
GSE233441_1_v_0_tnnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02097
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24078
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11263679-41598_2024_66946_MOESM1_ESM.pdf-13-ZNF213_ZNF213	Rummagene Transcription Factor Associations 2026	1.0	null
cellular response to starvation	GO Biological Process Annotations 2023	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62764
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979489
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975085
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.499614
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860342
GATA2	ChEA Transcription Factor Targets	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.125413
MAFK_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHEMBL513147	DeepCoverMOA Drug Mechanisms of Action	1.0	0.7
MAP1A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33027
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.949452
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77959
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IB-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	1.38329
Sapling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05204
autophagosome membrane	GO Cellular Component Annotations 2023	1.0	null
abnormality of the head	GWASdb SNP-Phenotype Associations	1.0	0.146947
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML2-OVERLAP_GENES_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87683
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7430-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08129
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268057
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901121
Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
Procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50217
hsa-miR-3545-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrion disassembly	GO Biological Process Annotations 2023	1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tubulin binding	GO Molecular Function Annotations 2023	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836072
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.414708
SAP30	ENCODE Transcription Factor Targets	1.0	null
vacuolar membrane	GO Cellular Component Annotations 2025	1.0	null
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12698
Root cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31277
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.151703
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML2-CLOSEST_GENE_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.02844
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5274
GSE196117_1_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27836
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862294
skin_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.19577
Autophagy - animal	KEGG Pathways 2026	1.0	null
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.540405
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31629
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acute leukemia	GWASdb SNP-Phenotype Associations	1.0	0.502291
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.158201
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44605
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.961913
VE-821	DeepCoverMOA Drug Mechanisms of Action	1.0	1.24
Pimavanserin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.73
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47603
organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949916
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8421
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934314
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946763
TC-95-IR96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.332624
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04747
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Ubiquitin activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.03
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.29
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22167
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1079-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Blond vs. brown/black hair color	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
LDN-192960	DeepCoverMOA Drug Mechanisms of Action	1.0	0.85
EB-82-HZ30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399141
UNC1215	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
UAMC00039	DeepCoverMOA Drug Mechanisms of Action	1.0	0.41
HD-19-IW09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.377941
GATA2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19191
GTF3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38136
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0994
umbilical vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196565
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4155
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83775
HERC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19643
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77792
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.913111
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRA_01_115	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65169
PMC10709142-41556_2023_1281_MOESM2_ESM.xlsx-Supplementary_Table_1-CLUSTER_1_MAF_upregulated_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50618
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060306
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905256
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16364
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
autophagic vacuole membrane	GO Cellular Component Annotations 2015	1.0	null
ATG10	Pathway Commons Protein-Protein Interactions	1.0	null
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04618
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04938
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277024
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02841
GTEX-WOFL-0826-SM-3MJG1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18301
abnormality of the nose	GWASdb SNP-Phenotype Associations	1.0	0.396183
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.65238
Plastoglobule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.547
mda-mb-231 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.521223
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40497
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.54363
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Dihydroartemisinin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.81
NVP-BHG712	DeepCoverMOA Drug Mechanisms of Action	1.0	1.84
BB-87-SF89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.464273
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361755
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29275
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD-96-HO43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2019
RAP1GAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37367
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272265
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63219
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD-47-YL43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.645232
NUDT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11584
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30604
GTEX-PSDG-0326-SM-48TCP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918821
abnormality of head or neck	GWASdb SNP-Phenotype Associations	1.0	0.146947
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.95364
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10565
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.846325
mitochondrion degradation	GO Biological Process Annotations 2015	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Amphisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66661
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.994459
VARS	Pathway Commons Protein-Protein Interactions	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.965235
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.637079
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31798
GATA1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sunitinib	DeepCoverMOA Drug Mechanisms of Action	1.0	1.71
Acute Myeloid Leukemia_LAML_TCGA-AB-2998-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
SOX2-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.471858
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256563
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44984
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57446
arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173314
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236627
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.59441
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.63327
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09191
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44794
PMC4835965__F4	PFOCR Pathway Figure Associations 2023	1.0	null
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42635
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215465
cellular response to starvation	GO Biological Process Annotations 2015	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20X-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.3
PF429242	DeepCoverMOA Drug Mechanisms of Action	1.0	0.71
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
A549_LUNG	CCLE Cell Line Proteomics	1.0	2.0225
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49244
Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C-33A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96294
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5902
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94949
VA-06-DB75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390793
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273873
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RBBP7	Pathway Commons Protein-Protein Interactions	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleophagy	GO Biological Process Annotations 2015	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.15524
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL1-CLOSEST_GENE_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08489
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50282
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27285
T3M3	DepMap CRISPR Gene Dependency	1.0	2.23706
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DD-74-PJ26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.77325
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPA2B1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4021073-1471-2407-14-278-S4.xlsx-Sheet1-Supplementary_Table_S5_Genes_with_GATA3_ChIP-seq_peak_within_10kb_from_transcription_start_site_TSS_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830301
Gerontoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.161
Lung adenocarcinoma_LUAD_TCGA-75-7027-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microtubule	GO Cellular Component Annotations 2015	1.0	null
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80005
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30391
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12945
Nexturastat A	DeepCoverMOA Drug Mechanisms of Action	1.0	1.78
Midbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.085
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52886
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7583-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF274_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.5095
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67848
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61335
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-27514584-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62367
SLC16A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66662
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35748
decreased susceptibility to induced morbidity/mortality	MGI Mouse Phenotype Associations 2023	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10287
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31419
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39696
disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.414708
7,3,4-THIF	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04446
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.770541
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222874
Autophagosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.499
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.550564
Ubiquitin-related domain	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26696
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10416
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
16273092-TableS1c	GeneSigDB Published Gene Signatures	1.0	null
Stereotypic movement disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
Vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047616
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88556
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87399
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59173
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.01724
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859913
SRF	ENCODE Transcription Factor Targets	1.0	null
umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.14272
connecting stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.139041
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04748
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22626
Acute Myeloid Leukemia_LAML_TCGA-AB-2981-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926035
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840086
NCIH1299_LUNG	CCLE Cell Line Proteomics	1.0	2.36048
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
senescence-associated vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.892
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906858
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07114
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890109
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.183352
GATA1	ChEA Transcription Factor Targets	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TK-01A-42R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TA-19-YA45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211075
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99418
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9151
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00086
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.929301
NRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42381
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Companion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL11A	ENCODE Transcription Factor Targets	1.0	null
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200955
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3123
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.26764
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
DESI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23147
POLR2A_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.617
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00133
CAMKK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26732
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5698-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29635
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acute lymphatic leukemia	GWASdb SNP-Phenotype Associations	1.0	1.16177
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.62699
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849061
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.973279
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24237
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.64729
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GB-84-KP45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277085
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294373
HC-01-FD24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30131
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.83216
GSE211128_9_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATG16L1	Pathway Commons Protein-Protein Interactions	1.0	null
Abemaciclib	DeepCoverMOA Drug Mechanisms of Action	1.0	1.71
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2841-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37162
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06644
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.032
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.661267
IGR37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70712
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77213
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915931
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06417
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10287
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.893762
ACADSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15865
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09117
Root quiescent center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
MEF2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17185
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	4.8509
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.439012
BD-49-MD69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303507
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29362
response to external stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	1.0	3.0939
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4590607__F3	PFOCR Pathway Figure Associations 2024	1.0	null
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.398193
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.562514
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13862
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288602
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971918
NB17	DepMap CRISPR Gene Dependency	1.0	5.76546
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995249
YA-44-LW45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350725
RFX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832376
PMC7866901__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28846
Autophagosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Celastrol	DeepCoverMOA Drug Mechanisms of Action	1.0	1.1
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312063
Lewy body-like hyaline inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
endomembrane system	GO Cellular Component Annotations 2015	1.0	null
GTEX-QCQG-1826-SM-2S1P2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865039
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852384
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOMM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99927
SB-224289	DeepCoverMOA Drug Mechanisms of Action	1.0	1.84
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.9699
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03958
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.997071
BE-28-WW67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210377
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051651
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4389
SPI1	ChEA Transcription Factor Targets	1.0	null
extrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7292
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896871
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.60222
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860329
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37084
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.491
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
AB-80-CK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222573
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88322
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-7268-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9204
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.96417
NCIH2052_PLEURA	CCLE Cell Line Proteomics	1.0	5.10287
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5739
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07502
PGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54374
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26886
BB-87-SF89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.425151
Endodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
Sarcoma_SARC_TCGA-QQ-A8VF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973625
mitophagy	GO Biological Process Annotations 2025	1.0	null
KM12	CCLE Cell Line Gene CNV Profiles	1.0	1.37924
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21495
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967702
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.387481
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YLPM1	Pathway Commons Protein-Protein Interactions	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305968
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48377
GA-87-BR97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.475917
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15238
vacuole organization	GO Biological Process Annotations 2015	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1536
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28992
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304492
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72269
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT1_01_154	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.51006
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein complex	GO Cellular Component Annotations 2015	1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04989
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08526
macroautophagy	GO Biological Process Annotations 2023	1.0	null
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0926-SM-4DM5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943225
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46968
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10258
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01938
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7697
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.969053
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062204
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31502
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.34914
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0994
Rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2141
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04446
WA-15-KX40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263089
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35871
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04244
GTEX-SNMC-0426-SM-4DM5Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09703
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093655
NVP-BSK805	DeepCoverMOA Drug Mechanisms of Action	1.0	2.51
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL3-CLOSEST_GENE_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
MMS22L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08012
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16739
NB-12-ZK38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230704
CREBBP	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6064
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6284
Glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-1526-SM-48TDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0624
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05236
Prefrontal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.006
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46735
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5526
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927076
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.385651
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.11828
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06347
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38742
microtubule binding	GO Molecular Function Annotations 2025	1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.484645
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
D423MG	DepMap CRISPR Gene Dependency	1.0	5.80844
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46352
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67246
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.545081
SPI1	ENCODE Transcription Factor Targets	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13083
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5976
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55012
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042501
SRF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
RELA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05926
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0283
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.335153
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83836
IGR39	DepMap CRISPR Gene Dependency	1.0	2.6034
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13634
hsa-miR-320b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75646
CYB5RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02111
NLGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1096
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94485
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878342
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8442-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55792
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0706
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18253
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.39442
GSE143406_1_v_0_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Phosphatidylinositol 3-kinase complex, class III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.146
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-86-BE39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255739
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056033
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76919
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1737
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
response to stress	GO Biological Process Annotations 2015	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	1.0	1.03822
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-629	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.19792
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072787
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41814
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.27859
hsa-miR-4679	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Palisade parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.685909
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.676094
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8753
A375SKINCJ1	DepMap CRISPR Gene Dependency	1.0	3.41598
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.686465
cellular component organization	GO Biological Process Annotations 2015	1.0	null
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.93494
mediator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.672894
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09527
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56467
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37084
PMC8044433-mmc4.xlsx-Sheet1-Acute_LPS_Microglia_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
tubulin binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-570	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
MRS 2578	DeepCoverMOA Drug Mechanisms of Action	1.0	0.6
KMS11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33558
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19172
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_12_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67519
OC-10-FB51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06074
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20985
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84074
cerebellum	HPA Tissue Protein Expression Profiles	1.0	0.929301
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06307
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08286
autophagosome assembly	GO Biological Process Annotations 2023	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45785
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68179
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-56-XL71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418683
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34329
TBC1D2B	Pathway Commons Protein-Protein Interactions	1.0	null
SKNAS	CCLE Cell Line Gene CNV Profiles	1.0	1.55746
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
J-82 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30293
LEPRE1	Pathway Commons Protein-Protein Interactions	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842171
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3043
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93282
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.941324
Mitophagy - animal	KEGG Pathways 2026	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917248
membrane part	GO Cellular Component Annotations 2015	1.0	null
NFE2	ENCODE Transcription Factor Targets	1.0	null
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1685
organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.181227
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
TDRD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26926
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4459
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231305
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069635
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.51489
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WASF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40359
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05485
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10565
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4005
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.519173
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091102
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41399
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GA-28-SS67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3228
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8005-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.07494
macromolecular complex binding	GO Molecular Function Annotations 2015	1.0	null
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96729
Acute lymphoblastic leukemia (childhood)	GWAS Catalog SNP-Phenotype Associations	1.0	0.351407
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.35888
Mononuclear cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061773
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40164
UNC 0638	DeepCoverMOA Drug Mechanisms of Action	1.0	2.17
17210724-Table1	GeneSigDB Published Gene Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5557-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.65145
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985875
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30284
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052458
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38935
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06298
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.425756
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21057
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38628
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856421
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78688
cellular response to extracellular stimulus	GO Biological Process Annotations 2015	1.0	null
PMC7866901__F1	PFOCR Pathway Figure Associations 2024	1.0	null
PCI4B	DepMap CRISPR Gene Dependency	1.0	3.12527
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81412
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.138791
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78076
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856414
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832716
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35392
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01806
H2AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35525
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95937
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843191
GRAMD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10469
H-1152	DeepCoverMOA Drug Mechanisms of Action	1.0	0.43
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28813
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02381
UBTF	ENCODE Transcription Factor Targets	1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Familial hemophagocytic lymphohistiocytosis 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.179167
Gedatolisib	DeepCoverMOA Drug Mechanisms of Action	1.0	1.68
BIX 01294	DeepCoverMOA Drug Mechanisms of Action	1.0	1.94
GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275794
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-47-IB34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251091
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875056
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371455
AC-49-NG46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215504
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.490945
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16398
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.2376
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00199
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.999166
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.691887
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877521
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
NMUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88834
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052458
MAFK	ENCODE Transcription Factor Targets	1.0	null
VD-41-XP62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31473
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05303
Atg1/ULK1 kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.509
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52974
ATG12	Pathway Commons Protein-Protein Interactions	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.909961
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.525
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.291
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2298
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2705
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46213
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
FOXM1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03678
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNE-9605	DeepCoverMOA Drug Mechanisms of Action	1.0	0.2
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lsm2-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.165
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040129
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825047
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.986997
S0-EE-Y6WJ_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26423
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845152
AD-40-WB93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209137
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399521
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.44203
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVK18	DepMap CRISPR Gene Dependency	1.0	2.19127
JHU011	DepMap CRISPR Gene Dependency	1.0	2.39866
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22858
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43897
RUNX1	ChEA Transcription Factor Targets	1.0	null
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3356
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65895
Phagophore assembly site membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.138
20368555-TS-2	GeneSigDB Published Gene Signatures	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3846
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19372
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049531
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7415-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157397
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.743855
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8858
Lung adenocarcinoma_LUAD_TCGA-67-3772-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
F36P	DepMap CRISPR Gene Dependency	1.0	2.57902
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIMM23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13492
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z1-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964948
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37608
ubiquitin protein ligase binding	GO Molecular Function Annotations 2023	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859913
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272846
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.96907
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.473944
AGK2	DeepCoverMOA Drug Mechanisms of Action	1.0	0.8
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278943
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95517
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.402159
ATG2-ATG18 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.91268
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.46012
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05725
FARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3275
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78285
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09983
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-76-HU27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.943846
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.919149
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13943
cytoskeletal protein binding	GO Molecular Function Annotations 2015	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EJM	CCLE Cell Line Gene CNV Profiles	1.0	2.20367
MEF2C_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Y-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57379
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36436
H4 neuroglioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56458
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34932
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19664
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45546
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19296
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244409
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42578
GATA2	ENCODE Transcription Factor Targets	1.0	null
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19062
CTBP2	ENCODE Transcription Factor Targets	1.0	null
SW837	DepMap CRISPR Gene Dependency	1.0	2.07226
organelle organization	GO Biological Process Annotations 2015	1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-P4PP-1526-SM-3P61M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931395
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50238
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04486
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14013
JF-30-FW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.501758
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.53021
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.257588
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoid leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.414708
vesicle	GO Cellular Component Annotations 2015	1.0	null
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.817456
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04188
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1072-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102587
GB-98-IZ84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204074
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vacuolar membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.355788
NCIH2170	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36697
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75292
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00491
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10049
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.869536
Secondary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.576
SCML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33086
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.09746
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84066
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51889
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16206
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
U-138MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
MLN4924	DeepCoverMOA Drug Mechanisms of Action	1.0	1.61
L755507	DeepCoverMOA Drug Mechanisms of Action	1.0	0.48
GABRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1566
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
Taranabant	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.58
CB-55-AK76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227155
FOXO3	ChEA Transcription Factor Targets	1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.87064
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04668
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01259
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15373
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0981
cancer	GWASdb SNP-Disease Associations	1.0	0.141697
lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.418861
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.30123
BCL3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23243
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320485
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00846
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-6545-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.849469
Lung squamous cell carcinoma_LUSC_TCGA-34-5241-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7052
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41714
Epithalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.402
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Phagocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401506
hsa-miR-452	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-2.08941
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5O9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.2376
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00565
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27878
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4448
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.818312
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A8BS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.607139
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL1-OVERLAP_GENES_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900014
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.658499
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.863491
MEF2C_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3973	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42633
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59173
PANC0327	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66501
AD-00-WA10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260008
15548681-Table2	GeneSigDB Published Gene Signatures	1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843729
FBXW11	Pathway Commons Protein-Protein Interactions	1.0	null
BATF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
B-cell acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40981
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DF-00-BU08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262628
GABARAP	Pathway Commons Protein-Protein Interactions	1.0	null
SYNCRIP_OE_GDS4596_85_human_SW480	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06298
SREBF1	ENCODE Transcription Factor Targets	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51949
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939903
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Untreated-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
DA-10-GX45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24557
cell part	GO Cellular Component Annotations 2015	1.0	null
17714734-Table4	GeneSigDB Published Gene Signatures	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26628
NR2F2	ENCODE Transcription Factor Targets	1.0	null
Kaposi sarcoma-associated herpesvirus infection	KEGG Pathways 2026	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUCCT1	DepMap CRISPR Gene Dependency	1.0	2.14352
18794137-SuppTable1c	GeneSigDB Published Gene Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2900-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	4.54858
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222238
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956147
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946562
QF-00-NO42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.279625
GTEX-RNOR-1326-SM-48FDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23214
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.889261
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.24742
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IQGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06088
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149760_0_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13558
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OD-96-OP94_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.417006
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9516
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16121
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.453595
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50449
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XYKS-1226-SM-4BRVI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99995
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13148
HD-89-HC56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212808
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.78581
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_no_change_in_MLL-AF4_ChIP-seq_signal_28_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
MEF2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59155
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932584
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9903
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JVM3	CCLE Cell Line Gene CNV Profiles	1.0	1.44745
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U7-06A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.35267
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q9-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992178
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217946
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32361
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338073
RERFLCMS_LUNG	CCLE Cell Line Proteomics	1.0	5.39888
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0926-SM-4LVMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15688
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
LCL161	DeepCoverMOA Drug Mechanisms of Action	1.0	0.51
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03646
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukemia	GWASdb SNP-Phenotype Associations	1.0	0.338078
SP1	ENCODE Transcription Factor Targets	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7433-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01575
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4389
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZB-29-GC39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31039
MDAMB415	DepMap CRISPR Gene Dependency	1.0	3.25072
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831704
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066159
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40439
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848163
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4152
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A551-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Aggresome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.945
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ICC12	DepMap CRISPR Gene Dependency	1.0	4.64754
Brain Lower Grade Glioma_LGG_TCGA-E1-5319-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autophagosome membrane	GO Cellular Component Annotations 2025	1.0	null
abnormality of the face	GWASdb SNP-Phenotype Associations	1.0	0.171059
8-MG-BA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.984569
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852995
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1667
AZ505	DeepCoverMOA Drug Mechanisms of Action	1.0	1.02
peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.161912
GATA1-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
IM95	DepMap CRISPR Gene Dependency	1.0	3.30119
EIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28698
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56893
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043371
Obatoclax	DeepCoverMOA Drug Mechanisms of Action	1.0	2.47
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49244
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08401
Rectum adenocarcinoma_READ_TCGA-DC-6683-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-30-GH67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215958
CCNH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8181
NU7441	DeepCoverMOA Drug Mechanisms of Action	1.0	1.88
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.974246
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4328	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.729982
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.943189
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.626168
ECI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05626
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29717
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.69835
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849061
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4835965__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1538
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pathways of neurodegeneration - multiple diseases	KEGG Pathways 2026	1.0	null
HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.027
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44607
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914522
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894182
PP2	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.52
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836055
placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105719
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891174
RPL23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64294
protein complex binding	GO Molecular Function Annotations 2015	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.388296
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.799811
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65313
MAP1LC3B	Hub Proteins Protein-Protein Interactions	1.0	null
neoplasia of the nasopharynx	GWASdb SNP-Phenotype Associations	1.0	1.16177
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22845
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0981
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225468
G402	DepMap CRISPR Gene Dependency	1.0	4.01469
EGR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BECKER	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-1.03641
Fedratinib	DeepCoverMOA Drug Mechanisms of Action	1.0	2.94
DUSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41581
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.045
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BFTC905	DepMap CRISPR Gene Dependency	1.0	2.30757
BCL11A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25385
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3536
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10046
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4946
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362192
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.2069
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918226
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72375
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11675
TGX-221	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33365
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232434
MDAMB231	DepMap CRISPR Gene Dependency	1.0	2.39604
ZB-29-GC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.651294
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21507
Autophagy protein Atg8 ubiquitin like	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2165
PMC9314667-Table_1.xlsx-Regulons-TFAP2A_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2515
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.10055
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GBAS	Pathway Commons Protein-Protein Interactions	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334619
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TC-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042517
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6168
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.298262
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HE-16-PO98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209967
EMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02508
bone marrow	HPA Tissue Protein Expression Profiles	1.0	0.929301
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-62-AQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312403
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.846574
QE-98-XD90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207996
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241415
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	1.82164
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984738
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4236
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.36444
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.612129
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.482546
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2665-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72047
Brain Lower Grade Glioma_LGG_TCGA-DB-5279-01A-03R-2347-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856628
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.555977
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93787
CHP212	DepMap CRISPR Gene Dependency	1.0	2.23706
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
HCC1187	DepMap CRISPR Gene Dependency	1.0	3.11157
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSU	DepMap CRISPR Gene Dependency	1.0	3.20822
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.528957
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57667
MYCN_01_296	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61753
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31246
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041296
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EB-19-SM10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.423046
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
BD-38-QC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.585184
C8orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27296
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62236
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
macroautophagy	GO Biological Process Annotations 2025	1.0	null
TD-17-NF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263041
ARL 17477	DeepCoverMOA Drug Mechanisms of Action	1.0	1.31
BE-66-UB12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27854
BI 2536	DeepCoverMOA Drug Mechanisms of Action	1.0	2.22
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19745
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826054
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35765
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.20673
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05824
VA-48-RJ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25369
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.71851
LU99	DepMap CRISPR Gene Dependency	1.0	5.76668
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968836
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PD-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH520_LUNG	CCLE Cell Line Proteomics	1.0	2.17003
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52489
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24286
Amyotrophic lateral sclerosis	KEGG Pathways 2026	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ESS1	DepMap CRISPR Gene Dependency	1.0	2.57927
Stromule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.7
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46842
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.420898
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68451
AA-94-TU18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.64872
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.348614
E2F4	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E2-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057314
UTX-26944678-CHIP-SEQ-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59036
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FD-20-OG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228351
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.96417
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.14346
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_4_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3729
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824852
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831704
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48245
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.901
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41014
Perturb_14500_KD_RUNX1_SRP265128	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.96736
hsa-miR-548l	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hsa-miR-320d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93038
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane organization	GO Biological Process Annotations 2015	1.0	null
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14937
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.377662
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-1178	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MKN28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Amsacrine	DeepCoverMOA Drug Mechanisms of Action	1.0	1.94
GSE211128_7_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
DA-35-DU85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.841274
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994221
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.41663
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.124
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935492
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.313869
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059893
SNU869	DepMap CRISPR Gene Dependency	1.0	4.61719
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.93927
huvec cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.369747
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18658
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059619
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.596471
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56237
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76636
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE252958_1_v_0_znf469_human	RummaGEO Gene Perturbation Signatures	1.0	null
IC-80-CT90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262697
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0994
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X2-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.10518
IRF3	ENCODE Transcription Factor Targets	1.0	null
MYLA	DepMap CRISPR Gene Dependency	1.0	3.66639
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.21626
Receptacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25706
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62811
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18165
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853156
neural crest	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.566428
CHD7	ENCODE Transcription Factor Targets	1.0	null
verob4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
Chloroplast stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
Omegasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5117
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60817
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-55-AK76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250671
EP300_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0826-SM-46MUS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41044
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.61223
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
496100499_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65929
PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_ID_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32201
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056394
RAD51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93168
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.29477
ZNF608	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88096
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47511
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62397
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961272
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vilazodone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.74
hsa-miR-211	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
KYSE220	DepMap CRISPR Gene Dependency	1.0	6.16472
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22966
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM151A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22737
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4B-Supplemental_Table_S4B_Differentially_expressed_genes_upon_ZFX_Knock_down_in_MCF-7_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08401
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KB-78-BE93_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267466
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11464
pharynx cancer	GWASdb SNP-Disease Associations	1.0	0.59062
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CORL23	DepMap CRISPR Gene Dependency	1.0	3.36023
WH-4-023	DeepCoverMOA Drug Mechanisms of Action	1.0	1.97
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12676
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.86677
PMC7098486-mmc2.xlsx-Kgg_Quant_NGN2_AAVS_-_WCL-Unnamed_2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
nasopharynx carcinoma	GWASdb SNP-Disease Associations	1.0	1.32598
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6611
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834893
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.10616
hsa-miR-320a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
KMH2	CCLE Cell Line Gene CNV Profiles	1.0	2.09833
hsf1_19179333_rko_colon_carcinoma_lof_human_gpl6244_gse12762	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.15432
KLF4_01_341	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60503
Phagocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
Lung squamous cell carcinoma_LUSC_TCGA-39-5036-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6289
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.5066
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24835
autophagosome assembly	GO Biological Process Annotations 2025	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.46344
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10515
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205363
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46329
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39681
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DE-73-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.986321
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28175
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9669
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75254
AZD8055	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.06
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A1L4-01A-12R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08391
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49685
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.354
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77963
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07234
MSGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0878
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.6394
SNAI1_OE_GDS4596_344_human_SW480 - Colorectal cancer cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65705
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK8	DepMap CRISPR Gene Dependency	1.0	2.18905
GTEX-XYKS-2226-SM-4E3IU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31452
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34006
IKZF1	ENCODE Transcription Factor Targets	1.0	null
AD-52-UZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287498
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94136
GSE226249_2_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294775
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.821791
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01086
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
PMC6823153-NIHMS1535502-supplement-3.xlsx-LSD1_SupplData1-Supplementary_Data_1_Potential_common_target_genes_of_LSD1_and_GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
umbilical vein endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.369373
CGP77675	DeepCoverMOA Drug Mechanisms of Action	1.0	1.57
NFIC	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.94422
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.336478
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70205
NB4	CCLE Cell Line Gene CNV Profiles	1.0	1.44561
MAF	MotifMap Predicted Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF749	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50837
response to stimulus	GO Biological Process Annotations 2015	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14013
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058883
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.1908
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307259
LPCAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16798
WD-62-UB45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226136
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.72119
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5531
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10856
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.943285
PF-84-RH50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329626
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07287
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.64854
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KB-78-BE93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.824895
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1877
PMC9490101-mmc3.xlsx-Sheet1-Supplementary_Table_3_Differentially_expressed_genes_in_CASC11_KD_MHCC-97H_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JA-26-YQ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51386
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GTEX-PWOO-0626-SM-48TZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959069
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25239
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.20847
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59555
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MT-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.50595
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.94026
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895934
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0574
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.904522
QE-35-YE15_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226689
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876857
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041522
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64822
PMC6411037-NIHMS981149-supplement-4.xlsx-Table_S3D-Table_S3D_Result_of_GSEA_with_human_ST-EPN_gene_set_DEGs_in_PDGFA_tumors_relative_to_RELA_fusion_tumors_are_listed_in_the_table_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.781882
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06416
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7834-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824927
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.65007
CHD2	ENCODE Transcription Factor Targets	1.0	null
MRPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76753
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	1.0	3.46719
ubiquitin-like protein ligase binding	GO Molecular Function Annotations 2025	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836072
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32584
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.355856
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898704
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.25604
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2873-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SB 699551	DeepCoverMOA Drug Mechanisms of Action	1.0	0.72
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.1413
UACC257	CCLE Cell Line Gene CNV Profiles	1.0	1.91801
Pineal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.402
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76804
AC-43-ZC52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307767
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27473
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59008
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30038
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.85329
cellular response to stress	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.868039
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.947818
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086326
Null cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.232
ASPHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05678
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847985
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861355
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.368518
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02065
hsa-miR-3614-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MEF2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-17-YW85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243653
16728581-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SB290157	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.27
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920464
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917962
PMC5263239-mmc2.xls-KOPN-8_-_MLL-ENL-Non-spreading_targets_gene_names_1358_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277462
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A54R-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphocytic choriomeningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
Chronic mucocutaneous candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle assembly	GO Biological Process Annotations 2015	1.0	null
cellular response to nitrogen starvation	GO Biological Process Annotations 2023	1.0	null
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09816
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL11A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LF-94-HB11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.358184
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46581
Natural killer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.232
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50188
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970119
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923012
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4590607__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Autophagosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.393217
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.10055
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19019
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050899
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-1326-SM-4AT4F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832901
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970119
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
PAX5	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13667
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.58509
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.438927
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202159
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39964
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27735
EZH2	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZM-1126-SM-4DXUB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934246
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal intestinal goblet cell morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902225
hsa-miR-204	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
Mifepristone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37616
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF274	ENCODE Transcription Factor Targets	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219269
Dendritic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.182
PBX3	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFATC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11317
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.990587
LPAR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17642
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18878
QA-14-AU91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245513
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937204
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.583232
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830643
Esophageal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20191
LCLC-103H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.391267
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.910128
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3335
JP1302	DeepCoverMOA Drug Mechanisms of Action	1.0	0.73
autophagosome organization	GO Biological Process Annotations 2023	1.0	null
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SE-81-RI20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.57891
16849537-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00882
ARID3A	ENCODE Transcription Factor Targets	1.0	null
umbilical vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.189488
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.24747
GD-46-BU97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.703665
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.919914
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86424
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.577237
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962893
GATA3	ENCODE Transcription Factor Targets	1.0	null
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957678
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898976
hsa-miR-188-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978764
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4731-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AZD4547	DeepCoverMOA Drug Mechanisms of Action	1.0	1.38
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71511
abnormality of the nasopharynx	GWASdb SNP-Phenotype Associations	1.0	1.16177
TEAD4	ENCODE Transcription Factor Targets	1.0	null
TECPR1	Pathway Commons Protein-Protein Interactions	1.0	null
pre-autophagosomal structure	GO Cellular Component Annotations 2015	1.0	null
USP11	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39167
cellular process	GO Biological Process Annotations 2015	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular response to nutrient levels	GO Biological Process Annotations 2015	1.0	null
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.77599
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.882465
RXRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.23
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98792
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.855816
EP300_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.972415
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7793-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87653
UA-39-TN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376424
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77635
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.27323
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07945
SNU1196	DepMap CRISPR Gene Dependency	1.0	2.49354
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.532326
MERO48A	DepMap CRISPR Gene Dependency	1.0	3.151
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055104
DPP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42684
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19133
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03958
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.90868
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.685493
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10032
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10742
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830643
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319596
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QA-34-PH05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231594
TCF4	ChEA Transcription Factor Targets	1.0	null
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96202
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37955
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7217
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24127
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29186
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.58546
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A6BH-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.83491
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12545
hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.414708
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17625
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.452959
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Bafetinib	DeepCoverMOA Drug Mechanisms of Action	1.0	1.51
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49867
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.8781
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.166547
microtubule binding	GO Molecular Function Annotations 2023	1.0	null
OLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2726
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.531752
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14478
bone marrow	HPA Tissue Gene Expression Profiles	1.0	1.79785
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48007
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.614727
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.587534
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09439
UNC 0631	DeepCoverMOA Drug Mechanisms of Action	1.0	1.1
GTEX-U3ZH-1126-SM-4DXUG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824331
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.951663
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08588
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293208
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-THP-1_MLL-AF9_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-1526-SM-4BONU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952937
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2919
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
microtubule binding	GO Molecular Function Annotations 2015	1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_Name_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
Achene	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.301
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.63827
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851806
AS-605240	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14303
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02721
Flavopiridol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.67
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.4401
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
response to extracellular stimulus	GO Biological Process Annotations 2015	1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.763
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43922
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.875703
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38301
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.602025
gastrointestinal system cancer	GWASdb SNP-Disease Associations	1.0	0.199577
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fat_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.833054
Momelotinib	DeepCoverMOA Drug Mechanisms of Action	1.0	1.03
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0177
MEC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10416
GTEX-XPVG-2726-SM-4B66W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99685
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.755555
QA-34-PH05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20444
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.751982
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1812
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.902537
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.836708
AC-75-CE67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295041
hsa-miR-30a-5p	MiRTarBase microRNA Targets	1.0	null
vacuolar membrane	GO Cellular Component Annotations 2015	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05824
STK410283	DeepCoverMOA Drug Mechanisms of Action	1.0	1.92
LU-99A	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
CTCF	ENCODE Transcription Factor Targets	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17856
FYCO1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
autophagic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.568416
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4381
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53055
AB-30-CR11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21936
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968836
GTEX-XBEW-1526-SM-4AT4K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860966
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6671
SH2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17992
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU-60019	DeepCoverMOA Drug Mechanisms of Action	1.0	1.34
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.28911
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-3769-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-320c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE143944_1_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A375	DepMap CRISPR Gene Dependency	1.0	2.24663
NFYB	ENCODE Transcription Factor Targets	1.0	null
USP7	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10485
torc1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.238837
MA-43-MR37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.777335
EC-41-PH99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268184
SNU423_LIVER	CCLE Cell Line Proteomics	1.0	2.07907
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091009
cerebral cortex	HPA Tissue Protein Expression Profiles	1.0	0.929301
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043675
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79268
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62487
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25248
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15299
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCHY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60952
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826429
Lung adenocarcinoma_LUAD_TCGA-75-5126-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3805
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	3.31113
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31009
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967417
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.795953
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.089756
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227445
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO824	DepMap CRISPR Gene Dependency	1.0	2.88323
skmel30	HPA Cell Line Gene Expression Profiles	1.0	2.19239
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.759038
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.48409
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203459
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.39366
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03845
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31819
Autophagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.136
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48686
GLYATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60813
intracellular organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.181227
PHF8	ENCODE Transcription Factor Targets	1.0	null
BC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979817
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
FLNC	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11722
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02722
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94034
SQSTM1	Pathway Commons Protein-Protein Interactions	1.0	null
SIX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15709
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908546
endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310059
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-FOS_mod_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.617109
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01059
autophagy	GO Biological Process Annotations 2015	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5247-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01943
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1466
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00404
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Paralytic poliomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BSPRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3399
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.73527
Peripheral blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.182
GTEX-XQ3S-1226-SM-4BOPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37516
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.29499
pb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A	ENCODE Transcription Factor Targets	1.0	null
CEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00314
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31022
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213207
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065023
NF-21-HQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.10499
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.364513
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84683
SACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22206
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27401
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20703
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EP-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999416
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.069314
H3K4me1_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0025
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836577
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21282
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	5.95722
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70929
PAX5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atg12-Atg5-Atg16 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.189
cell communication	GO Biological Process Annotations 2015	1.0	null
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919747
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33041
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059981
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846467
GE-34-TW62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.57216
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28348
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.770071
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.407666
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.279858
RELA	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946804
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
catabolic process	GO Biological Process Annotations 2015	1.0	null
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.535046
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC-71-BZ81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245742
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCOA5	Pathway Commons Protein-Protein Interactions	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02139
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60631
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.339138
PC-18-VX23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215059
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61398
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-93-BT88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30234
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09763
Volasertib	DeepCoverMOA Drug Mechanisms of Action	1.0	2.39
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.23372
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
CDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32981
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990771
KB-78-BE93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.339897
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6999
Mononuclear phagocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
ZNF207	Pathway Commons Protein-Protein Interactions	1.0	null
WM88_SKIN	CCLE Cell Line Proteomics	1.0	2.46962
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1098
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-75-LR63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365105
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05694
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16558
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12998
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	1.0	1.36572
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.139393
hippocampus	HPA Tissue Protein Expression Profiles	1.0	0.929301
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02963
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00701
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.523496
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Large granular lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.232
OA-54-FL10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213418
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C22orf23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31007
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19348
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7491
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_13_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
ubiquitin-like protein ligase binding	GO Molecular Function Annotations 2023	1.0	null
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.274394
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.29
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25416
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20457
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM52PE	DepMap CRISPR Gene Dependency	1.0	2.28871
CC-18-YW57_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.28443
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09791
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	1.0	1.72399
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DYNC1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74363
U-118MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RO495	DeepCoverMOA Drug Mechanisms of Action	1.0	0.77
lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.689634
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
KMS20	CCLE Cell Line Gene CNV Profiles	1.0	1.41363
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825308
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373575
Bosutinib	DeepCoverMOA Drug Mechanisms of Action	1.0	1.66
leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.414708
NCIH1915	DepMap CRISPR Gene Dependency	1.0	2.39304
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363322
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18325
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901711
TRIM28	ENCODE Transcription Factor Targets	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20581
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95709
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288255
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-common-common_genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_HL-60_and_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.833412
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00263
SAFB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
RELA_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A6YU-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7429
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87182
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHH7	DepMap CRISPR Gene Dependency	1.0	2.52026
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.895091
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853016
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.751033
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KH7	DeepCoverMOA Drug Mechanisms of Action	1.0	0.59
nuclear lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.242076
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.926763
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1924
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.04364
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.514
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle assembly	GO Biological Process Annotations 2023	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46371
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21181
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
EC-01-PH79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20429
TEAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23502
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18077
GTEX-RWS6-0426-SM-47JXH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49756
sc93	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
IGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9818
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
PRT062607	DeepCoverMOA Drug Mechanisms of Action	1.0	2.11
SREBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14814
ENL-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VU 0364739	DeepCoverMOA Drug Mechanisms of Action	1.0	2.72
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Amyloplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.124
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41189
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992614
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43306
RELA_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88363
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40532
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.07991
Plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
DA-10-GX45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246096
MM1S	CCLE Cell Line Gene CNV Profiles	-1.0	-2.26525
autophagic vacuole assembly	GO Biological Process Annotations 2015	1.0	null
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.565306
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.07832
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00002
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.896476
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.33676
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.07888
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167533
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24835
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277407
mitochondrion organization	GO Biological Process Annotations 2015	1.0	null
nucleoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.353282
ATF2	ENCODE Transcription Factor Targets	1.0	null
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.484986
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.414708
HIF1A_01_220	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.58552
GTEX-XUZC-0726-SM-4BOPH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22567
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.10207
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835236
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.41093
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.49166
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843729
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.76604
membrane fusion	GO Biological Process Annotations 2015	1.0	null
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00274
IRF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL3-OVERLAP_GENES_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1512
CREBBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67693
autophagosome maturation	GO Biological Process Annotations 2025	1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00237
TBP	ENCODE Transcription Factor Targets	1.0	null
QB-88-PG52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236864
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4529
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07075
GTEX-XUZC-0526-SM-4BOPF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876482
MXI1	ENCODE Transcription Factor Targets	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.340186
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29018
GATA1-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924314
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59173
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00607
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57791
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bronchial epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.252
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
Pepstatin A	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949623
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.10145
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06336
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.685291
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49381
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-60-LK14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412356
CREB1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35895
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23175
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981863
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NMS-873	DeepCoverMOA Drug Mechanisms of Action	1.0	2.26
SA-32-CC58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296598
Lung squamous cell carcinoma_LUSC_TCGA-85-6560-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.252
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
CB-55-AK76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330186
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69485
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1489
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076477
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the pharynx	GWASdb SNP-Phenotype Associations	1.0	1.16177
Ursodiol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
Rectum adenocarcinoma_READ_TCGA-F5-6812-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.362959
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20453
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01813
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.677711
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872791
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889536
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33227
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.468257
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PATU8902	DepMap CRISPR Gene Dependency	1.0	2.52347
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62856
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837335
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABARAPL2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.616
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.70663
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diisocyanate-induced asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1893
496100599_TCx_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00839
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.940571
Amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.29
TRIM28_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN-18 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
AB-18-YN11_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.388088
AD-51-FB60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296068
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72474
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.08173
NDFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62771
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03497
Monocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
STAT5A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
autophagosome	GO Cellular Component Annotations 2025	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936697
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11385
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221274
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3052
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.842077
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51841
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.24625
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.274
Flower stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25745
BE-73-KD75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.502012
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
ATG4B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896679
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46733
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10663
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873157
Breast_vHMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.40947
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.19172
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14735
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dami cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92976
Anamorelin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.52
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00715
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296367
PPWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29381
NCIH1355	DepMap CRISPR Gene Dependency	1.0	6.05382
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25484
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056174
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
GTEX-SUCS-1826-SM-32PM1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86352
Mesophyll cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951867
microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.494006
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.12
TDRD3-21172665-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Bronchial epithelial cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.252
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25883
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17125
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31559
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ICC3	DepMap CRISPR Gene Dependency	1.0	2.30553
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869127
molecular_function	GO Molecular Function Annotations 2015	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48479
DB-18-UF01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203338
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.04851
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.99091
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Poliomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885192
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPSF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39563
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.782962
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86805
MCM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34457
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28777
SPRYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40309
eGFP-NR4A1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12422825-aging-17-8-206293-s003.xlsx-i_MR_IP-Unnamed_5_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045301
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03904
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937093
SCC9	DepMap CRISPR Gene Dependency	1.0	6.35705
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.09952
AA-58-FJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.38747
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-1726-SM-4JBHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30308
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	5.98814
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19282
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.305
STK066844	DeepCoverMOA Drug Mechanisms of Action	1.0	0.39
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13634
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31474
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.192
skbr3	HPA Cell Line Gene Expression Profiles	-1.0	-1.38092
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50118
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80671
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JF-62-LU77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.377531
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.436971
N syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
vacuolar part	GO Cellular Component Annotations 2015	1.0	null
BATF	ENCODE Transcription Factor Targets	1.0	null
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
DD-74-PJ26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245712
GTEX-X261-0626-SM-3NMD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867097
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29706
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KC-95-ZW49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222375
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19498
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.491358
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
GTEX-PX3G-1526-SM-48U11	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38665
AB-82-EP26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236555
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.84117
AT 406	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
UMI-77	DeepCoverMOA Drug Mechanisms of Action	1.0	0.46
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052209
GTEX-OIZH-0226-SM-2YUMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16639
ATF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89859
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828421
IRF1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Precursor B-Cell Lymphoblastic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85429
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999115
PMC5503627-oncotarget-08-39497-s003.xlsx-hypo_in_shUHRF1_KD-Unnamed_7_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300537
NR2F2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.548233
Glutathione synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.202
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40798
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00333
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09301
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46966
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885215
CYP27C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77375
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CD-26-MB82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258736
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6817
EIF1AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06233
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1812
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26577
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93993
Brain Lower Grade Glioma_LGG_TCGA-VV-A829-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.826729
FOS	ENCODE Transcription Factor Targets	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.643947
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834453
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66445
P005091	DeepCoverMOA Drug Mechanisms of Action	1.0	0.53
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.640437
hematologic cancer	GWASdb SNP-Disease Associations	1.0	0.298262
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.31487
PRKACG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03114
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174617
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48959
GSK343	DeepCoverMOA Drug Mechanisms of Action	1.0	0.53
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47421
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.69199
HCT15	DepMap CRISPR Gene Dependency	1.0	3.36239
Nasopharyngeal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6085
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868186
GTEX-T5JW-0226-SM-4DM7I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62169
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
autophagy of mitochondrion	GO Biological Process Annotations 2023	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17919
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981836
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphoblastic leukemia	GWASdb SNP-Disease Associations	1.0	0.59062
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.36111
umbilical vein endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.210086
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.49632
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11178
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TI-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	2.14254
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26768
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056945
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular response to nitrogen starvation	GO Biological Process Annotations 2025	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-0626-SM-4DM6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10197
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25345
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831704
GTEX-RM2N-1126-SM-48FCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01609
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87053
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069274
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Thiothixene	DeepCoverMOA Drug Mechanisms of Action	1.0	1.27
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836047
T3M4	CCLE Cell Line Gene CNV Profiles	1.0	1.40328
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Central vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.461
BCBL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW48	DepMap CRISPR Gene Dependency	1.0	2.52362
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15084
OE33_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.9658
EP300	ENCODE Transcription Factor Targets	1.0	null
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41409
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.490352