association	dataset	threshold value	standardized value
L-1236	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K04468899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0003
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
positive regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5237
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38333
NSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69252
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54402
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.08675
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.01443
MTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40789
BRD-K22778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82289
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7503
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
BLOC1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61147
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02748
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11431
LRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39744
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89174
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06772
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50567
Perturb_12771_KO_Bin1_SRP201679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.80717
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66409
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0101
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08419
FGF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65073
Periventricular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13645
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19971
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45196
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE136238_1_v_2_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14924
BRD-A77328129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06477
CXCL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90531
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913479
C10orf95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34634
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922039
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938019
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
prazosin-6315	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10129
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HT-1197	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01112
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.217517
bone disease	GWASdb SNP-Disease Associations	1.0	0.140771
KLF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15531
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32246
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31701
SPEGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08787
EW-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
positive regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
BRD-K70276322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07018
BRD-K41025232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09073
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4901
BRD-K34506374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24714
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07887
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12427
KYSE520	CCLE Cell Line Gene Mutation Profiles	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79656
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.08462
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46455
TEX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95245
DANG	CCLE Cell Line Gene CNV Profiles	1.0	1.3517
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75271
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13141
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46274
HCC515	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49358
GSE199899_1_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52906
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.481772
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15939043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3168
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42409
RNF167	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47629
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31336762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09568
BRD-K15654812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21741
mood disorder	GWASdb SNP-Disease Associations	1.0	0.270671
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.144
LS411N	CCLE Cell Line Gene Mutation Profiles	1.0	null
MCAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16653
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42599
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7308_KD_IER3AS1_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.13488
CZIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29195
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48046422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49367
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44764
Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44772
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49487
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.00767
BRD-K97576000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47734
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K40189164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.12389
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837683
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.973662
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8163
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.47401
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46903
BRD-K58445641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26943
mental depression	GWASdb SNP-Disease Associations	1.0	0.506176
NUDT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22924
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855403
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6793
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34472
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89744
receptor signaling protein serine/threonine kinase activity	GO Molecular Function Annotations 2015	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0555
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22331
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16175
CMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16478
DECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4154
UPK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
FKBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59126
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
Perturb_15212_KO_Ifnar1_ERP120505	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71909
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52257
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8593
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04546
BRD-K69423881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54651
RAB11FIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01014
BRD-K25907192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44106
regulation of protein modification process	GO Biological Process Annotations 2015	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9591
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE126402_2_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.4645
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOC5	DepMap CRISPR Gene Dependency	1.0	2.59877
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-698-M	GDSC Cell Line Gene Expression Profiles	1.0	1.46364
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85895
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.63207
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31496
GSE87144_6_v_1_rorc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE150	CCLE Cell Line Gene Mutation Profiles	1.0	null
ChaGo-K-1	GDSC Cell Line Gene Expression Profiles	1.0	1.7272
BRD-K36952018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11412
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01381
VDR	ChEA Transcription Factor Targets	1.0	null
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05418
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.47751
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68D-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39569
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33537
GPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45851
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44564
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92268
RPS6KB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62361
Mr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874505
RHPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37257
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12479
BRD-K37831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.01595
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62379
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3949
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09562
layer 6a of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27614
UBE2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79199
MRPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40693
BRD-K80065513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04071
CRCGN008_HEPG2_24H:C05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0153
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72435943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58135
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947278
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43612
ISTMES2	CCLE Cell Line Gene Expression Profiles	1.0	1.49266
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836638
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JMSU1	CCLE Cell Line Gene CNV Profiles	1.0	1.6442
STK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80056
KATOIII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57994
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pulmonary fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18255
BRD-K39981110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1
biological_process	GO Biological Process Annotations 2015	1.0	null
LPS141	DepMap CRISPR Gene Dependency	1.0	3.18152
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06478
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67954
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26287
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63043
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48945
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53832
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25891
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55664
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84407
GSE81193_3_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03179
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84623
BRD-K59670689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80118
MZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37816
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29019
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8149
EXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85307
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55526
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.9348
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80457
Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828654
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03614
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27955
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02479
CACNG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01472
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93463
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11648256-mmc3.xlsx-Tab_S2_AA_Mod_27_SNP_BMI_INT-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19055
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43424
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
equilin-5620	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43106
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02803
GP2D	CCLE Cell Line Gene Mutation Profiles	1.0	null
RVH-421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the macula	GWASdb SNP-Phenotype Associations	1.0	0.807106
BRD-K44752001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02944
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91861
LGALSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57105
ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K68365891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50331
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85116
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838318
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38101
PMC10915192-ab-23-0304-Supplementary-Table-S7.pdf-22-CENPS_CENPS	Rummagene Transcription Factor Associations 2026	1.0	null
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5367
BRPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97866
YD38	DepMap CRISPR Gene Dependency	1.0	3.29758
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	0.829047
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8045
LPCAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72281
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26749
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2663
BL70	CCLE Cell Line Gene Expression Profiles	1.0	1.59049
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84002
CTSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13223
BRD-K72567746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19646
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41674
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0161
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43
Perturb_9740_KO_Kcnj11_SRP279345	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.42977
Ependymoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.297
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.77612
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K65913831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94964
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12195
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2178
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932946
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958962
abnormality of the retina	GWASdb SNP-Phenotype Associations	1.0	0.235591
NB10	GDSC Cell Line Gene Expression Profiles	1.0	1.79118
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07324
BRD-K17821077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18453
AGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34029
MDAMB231	CCLE Cell Line Gene Mutation Profiles	1.0	null
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99636
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10807
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53845
Interstitial lung disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
BRD-K58944125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29241
MEGF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86926
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Y-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908071
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29381
anion binding	GO Molecular Function Annotations 2015	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.04052
BRD-K41726296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27417
SOX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31087
BRD-K47092271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2463
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9983
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.034365
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44298
LIN37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35285
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM43A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37774
PLXNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
GLUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10469
JDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18501
nucleus of the stria medullaris (prethalamic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46274
ZNF891	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67608
BIIB068	DGIdb Drug Targets 2026	1.0	8.822
UCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74323
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880399
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865298
macular degeneration	GWASdb SNP-Phenotype Associations	1.0	0.807106
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76027
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883326
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
positive regulation of kinase activity	GO Biological Process Annotations 2015	1.0	null
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05953
HA1E	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874749
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19096
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03299
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30707
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826238
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91819
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26225
EFM-192A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RMG-I	GDSC Cell Line Gene Expression Profiles	1.0	1.62707
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845242
C17orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81959
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22407
BRD-K13389917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0938
HRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37959
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64848
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
TIGD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28349
JHOM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36268
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4316
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56921
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66655
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47798
BRD-K47536398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00456
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69361
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66088
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14967
Alveolar wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28374
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39758
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10007
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66051
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07321
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36502
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05234
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10166
HES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64922
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5979
non-proliferative fibrocystic change of the breast	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.916
MACF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09106
EW8	CCLE Cell Line Gene CNV Profiles	1.0	1.89146
BRD-K49529874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33742
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78491
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.861006
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80292
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894612
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_6365_KO_Hnrnpu_SRP250313	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.15523
IQCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74574
LBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56337
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04059
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2613
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8264
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03806
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12121
496100490_HIP_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79718
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20756
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29956
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5021
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91444
Perturb_13394_KD_AHR_SRP154013	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.25739
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4762
NEUROD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32131
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49138
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29505
MZT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38439
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32539
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12397
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06254
ZFP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72907
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13271
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02266
ZNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55748
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26195
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42411
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29569
GSE193351_4_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17473
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09317
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23212
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923725
BRD-K77787814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50458
BBS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84468
BRD-K74245698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40002
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IV-01A-22R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78603273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44431
BRD-K59626557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60396
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18117
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48345
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08307
Substantia nigra, reticular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00101
GSE112860_5_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2786
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
PMC10140619-mmc5.xlsx-Rank_Beta1-Beta3-Gene_BHLHE22	Rummagene Transcription Factor Associations 2026	1.0	null
NSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.29657
BRD-K15343038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35172
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43404
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85519
Perturb_14670_KO_Lkb1_ERP006813	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.5452
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.897
STXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43956
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01357
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6238
positive regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
ZBTB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65514
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
BRD-K42877297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11022
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91616
VPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21934
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8956
KARPAS-45	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48976
lomofungin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34892
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4596
BRD-K03496358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09788
BRD-K81501934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35875
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.959082
Gastric adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
BRD-K18600476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04564
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0592
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01217
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF778	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91033
DENND1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43056
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17295
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03305
BRD-K33953218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78117
NCIH1299	DepMap CRISPR Gene Dependency	1.0	3.02254
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11908
positive regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87524
BRD-K89232006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08971
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-x_LPS-BMDCs-kinase_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CDC25C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19913
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22766
intermediate stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85708
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966075
BRD-K30643363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43303
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00667
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T6MO-1026-SM-4DM72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996183
BRD-K78847404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07588
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4831
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hyperostosis	GWASdb SNP-Disease Associations	1.0	0.797385
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962012
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59797
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0219
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1335
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2269
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5247
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946032
HNF4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43707
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2362
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65E-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.39086
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.54
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851303
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.02991
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30685
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4489
JUND_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855403
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KP-N-YS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42801
MGRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5081
reticular formation of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21454
LAN-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869336
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38329
BRD-K15188108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11508
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99315
BRD-K80073743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00516
HOXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74393
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6745
ATXN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89962
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10567
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24711
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	2.18249
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984358
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25865
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06508
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90707
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13088
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08724
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
BRD-K51608472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63399
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8264
SMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
GSE226091,GSE226092_3_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARFGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9055
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88045
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11304
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01146
GSE186647,GSE217288_2_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ECC12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organelle organization	GO Biological Process Annotations 2015	1.0	null
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19706
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.399
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838699
PTPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31364
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74349
HS343T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02936
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39449072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51393
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82939
VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61727
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837683
KIF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64892
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07919
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0286
PTPN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9462
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	3.16762
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20265
JM1	CCLE Cell Line Gene Expression Profiles	1.0	1.65438
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-NR4A2-sequence_name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Pneumonitis	DisGeNET Gene-Disease Associations	1.0	null
PANC-03-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.69161
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36547
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09281
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09836
MAP3K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22324
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
SOX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4362
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.60962
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
SNU245	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7686
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8879
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HO-1-U-1	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12772_KO_Bin1_SRP201679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.07336
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13341
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39936
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832872
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2029
SW48	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K09521953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65833
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37723
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95467
ZNF224	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62402
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-02A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98764
JUND	ENCODE Transcription Factor Targets	1.0	null
HEC1B	DepMap CRISPR Gene Dependency	1.0	3.65692
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4592
PMC12629863-CAC2-45-1547-s002.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Kinases_predicted_to_phosphorylat_YY1_at_Ser247_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.036917
KMS21BM	CCLE Cell Line Gene Mutation Profiles	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880399
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97783
hsa-miR-4646-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01259
FGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32226
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6019
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72453
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07167
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98732
HEC6	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937039
BRD-K67096761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72768
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69298
Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05635
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15376
GTEX-SE5C-0926-SM-4BRUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946766
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11616
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62681
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88747
SK-MEL-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29839
BHLHA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53181
BRD-K10911459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24592
Keratoconus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K62841356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79463
regulation of protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
NR2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6048
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00904
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE88819_0_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10855
EYA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79468
BRD-K35132745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02278
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66574
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90997
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60618
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51316
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86424
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05953
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.874275
NCIH2171	CCLE Cell Line Gene Expression Profiles	1.0	1.58372
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82332258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53988
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_1160_KD_CELSR2_SRP149837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.6243
COLO792	CCLE Cell Line Gene Expression Profiles	1.0	1.52605
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26486
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01509
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52389
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38982
KMS34	CCLE Cell Line Gene Mutation Profiles	1.0	null
VDR-20736230-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H508	COSMIC Cell Line Gene Mutation Profiles	1.0	null
age related macular degeneration	GWASdb SNP-Disease Associations	1.0	0.917442
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47713
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75306
DM3	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K78961368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74616
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03407
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7433
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992525
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825584
Salivarygland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.00652
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01146
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38267
NCIH2196	CCLE Cell Line Gene Mutation Profiles	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3669
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93224
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32347
CALCOCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39741
GSE126463_6_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03339
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04308
LNZTA3WT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2BC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70021
VIPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18466
PHF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56336
BRD-K48308783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04233
BRD-K35171408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0062
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86224
USP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26617
Finding Of Mean Corpuscular Hemoglobin	DisGeNET Gene-Phenotype Associations	1.0	null
AURKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
hsa-miR-569	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
TOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2358
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41965
JHUEM7	DepMap CRISPR Gene Dependency	1.0	5.34914
HSPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
IRF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31248
CHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
BRD-K18313650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38949
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-A03764094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57842
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5273
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNASE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47218
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970146
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37304
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06478
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42462
BRD-K81669067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7752
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61916
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17398
CRCGN011_HEPG2_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22955
BRD-K00611112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65276
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892074
GAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92231
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94234
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.867905
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2301
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MUTZ8	DepMap CRISPR Gene Dependency	1.0	4.60068
TTC39C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65964
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3287
BACH1	ChEA Transcription Factor Targets	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
SPRING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79308
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8278
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BEN	CCLE Cell Line Gene CNV Profiles	1.0	1.80542
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DANG	DepMap CRISPR Gene Dependency	1.0	3.03629
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62176
CA46	CCLE Cell Line Gene Mutation Profiles	1.0	null
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	1.40264
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35312
map kinase kinase kinase activity	GO Molecular Function Annotations 2015	1.0	null
BASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21712
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19892
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72614
Warburg micro syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
BRD-K55679243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79313
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21337
ZFP90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5192
BRD-K42987166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27569
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3989
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGDIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99349
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79597
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
SCC4	DepMap CRISPR Gene Dependency	1.0	3.23104
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59931
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38735
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18161
positive regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
BRD-K42435091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03201
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HELA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GALNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53125
HSPB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38877
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87669982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07958
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
phosphotransferase activity, alcohol group as acceptor	GO Molecular Function Annotations 2015	1.0	null
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41458
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.205
CRCGN015_MCF10A_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29505
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78984
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04678
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
Spinocerebellar ataxia type 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914557
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27669
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45852
RAB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60698
MHHES1	CCLE Cell Line Gene CNV Profiles	1.0	1.39009
ITPRID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15805
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64996
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11034
protein kinase activity	GO Molecular Function Annotations 2015	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9577
SW900	CCLE Cell Line Gene CNV Profiles	1.0	1.50818
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12571
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68238
Perturb_1121_KD_E2APBX1_SRP115954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.61664
ZNF180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87332
BRD-K78395012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43102
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.62328
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8547
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZF-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19298
regulation of kinase activity	GO Biological Process Annotations 2015	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.3771
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.986249
BRD-K07414059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71734
BRD-K40960913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44678
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44258
BRD-K00086692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05688
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992369
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948524
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KP1NL	CCLE Cell Line Gene Mutation Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7993
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1769
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1708
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2369	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95547
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02599
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.134056
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77096
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968656
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
FASTKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78688
regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64006
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51572
regulation of protein kinase activity	GO Biological Process Annotations 2015	1.0	null
TRIM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00067
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GLT8D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1806
atp binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K90999585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22399
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00904
age-related macular degeneration	GWASdb SNP-Phenotype Associations	1.0	0.807106
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42801
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36129
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02653
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH520	DepMap CRISPR Gene Dependency	1.0	5.12374
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18416855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40643
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48154
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33206
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29319
Chronic Obstructive Airway Disease	DisGeNET Gene-Disease Associations	1.0	null
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04643
GA10	CCLE Cell Line Gene Expression Profiles	1.0	1.34935
BRD-K85418917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97211
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43003
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC12A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77894
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3461-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31743
Interstitial lung disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23309
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33905
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946211
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKN7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37184
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8788
SLC27A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81204
RPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73186
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23069
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37099
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.97423
POU2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88771
CDK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03474
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.059943
TEX264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16149
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21438
GSE155305_3_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06382
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855403
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3517
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2426
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16771
BUB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15915
CAMSAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.037871
FBXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20345
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26449
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.986618
SNU1040	CCLE Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866257
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOX17	JASPAR Predicted Transcription Factor Targets	1.0	null
depression	GWASdb SNP-Phenotype Associations	1.0	0.432488
regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
BRD-K27476975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02871
TIGAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94669
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K84388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22679
RMGI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65958
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14554
PTPMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35432
BRD-K33940145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44263
HLA-C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97213
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05953
CRCGN016_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13391
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884957
BRD-K17852428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32218
Serine/threonine-protein kinase, active site	InterPro Predicted Protein Domain Annotations	1.0	null
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SEMA4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67853
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92592
BRD-K49981566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19452
BRD-K49039223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03385
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K22670776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70702
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00042
hsa-miR-4686	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
IL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21692
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946032
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19394
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07325
HCC15	DepMap CRISPR Gene Dependency	1.0	3.71777
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.75704
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9726
ASS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39991
MICALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59955
RL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
HCT15	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23704
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8965
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03398
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC35B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19056
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
NDUFAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52454
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35823
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04678
DU4475	DepMap CRISPR Gene Dependency	1.0	2.32796
BRD-K31269097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56706
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51874
regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91383
Perturb_1178_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.6198
hsa-miR-151-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54348
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61614
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16103
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
KE39	CCLE Cell Line Gene Mutation Profiles	1.0	null
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6409
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21253
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0905
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6545
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39298
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.47884
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.99934
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836859
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996808
CCDC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90336
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39749
TCF7	ChEA Transcription Factor Targets	1.0	null
ZNF436	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94366
GSE163282_12_v_10_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20883
regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4499	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.495
RASSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48746
Bgm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
TAPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29185
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28209
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.872338
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933944
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1914
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of transferase activity	GO Biological Process Annotations 2015	1.0	null
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852184
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.59192
NDUFB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76777
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40218
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
BRD-K66526269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04368
PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1533
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84277
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78022
H2BC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59098
atropine oxide-4476	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2806-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65006
HSPA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92467
positive regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K43390655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38888
NCIH2009	CCLE Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_11_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88644
UBQLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80959
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80945
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74824
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.393
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54211
H4	DepMap CRISPR Gene Dependency	1.0	4.38807
CRCGN008_HEPG2_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09315
BRD-K38035271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04923
positive regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3152520-1479-5876-9-119-S2.XLS-Sheet1-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
layer 5 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38125
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	2.11622
BRD-K23553911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44168
FAM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97825
Medial geniculate complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53477
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6325
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.32417
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15711
CRCGN014_HEPG2_3H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00307
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53284
D-283MED	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
HUH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH508	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K71015709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22638
BRD-K96154586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5575
isthmic liminal reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07892
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16346
KMS34	DepMap CRISPR Gene Dependency	1.0	3.8738
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996586
SLC39A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40268
ING3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12815
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987121
BRD-A86748098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56338
BXPC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33803
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01437
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40462
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.85397
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928184
JUN	ENCODE Transcription Factor Targets	1.0	null
BRD-K61807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81714
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875774
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50637
DTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02021
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73769678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39294
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.86386
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57585
CHD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73351
SNU503	CCLE Cell Line Gene Mutation Profiles	1.0	null
REH	CCLE Cell Line Gene Expression Profiles	1.0	1.39395
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1263
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.136474
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52811
Influenza A	DisGeNET Gene-Disease Associations	1.0	null
BRD-K09511124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10428
NPAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45693
sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.63207
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
SLC11A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55315
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20951
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9204157__F4	PFOCR Pathway Figure Associations 2024	1.0	null
NCIH82	CCLE Cell Line Gene Expression Profiles	1.0	2.88058
BRD-K17367110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8944
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.26346
EEF1AKMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30515
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.867791
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88885
ANP32D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11712
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSUN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53876
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.41512
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866975
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	1.49303
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50366
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49177
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02355
SOCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80192
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.250807
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13716
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24545
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938019
HS706T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48187
cell part	GO Cellular Component Annotations 2015	1.0	null
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10657
rt112/84	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
BRD-K12469242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08465
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55319
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12656
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12828
BRD-K53619784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38841
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971266
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Trilateral retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.5169
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78781
CRCGN015_MCF10A.TP53.M_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24705
GTF2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2033
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76061
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38967
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.726
EJM	DepMap CRISPR Gene Dependency	1.0	3.08824
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35857
Submucosal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
PYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02779
Protein kinase, ATP binding site	InterPro Predicted Protein Domain Annotations	1.0	null
HT	CCLE Cell Line Gene Expression Profiles	1.0	1.60484
STC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46208
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1494
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11055867-41598_2024_60205_MOESM1_ESM.pdf-10-HNF4G_HNF4G	Rummagene Transcription Factor Associations 2026	1.0	null
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3781
BRD-K45043387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06265
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37963
BRD-K79937734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09718
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
SNU738	CCLE Cell Line Gene Mutation Profiles	1.0	null
LU-134-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGFB_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
PMC11185845-NIHMS1996282-supplement-Table_S1.xls-TableS1_txt-Kasumi_miR130_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
BRD-K54456668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00554
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.083397
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
anterior nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09984
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43482
globe disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.63207
G-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959706
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35906
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06753
BRD-K63800697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22755
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFKBIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28047
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
UCMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89114
r1 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85708
COGE352	DepMap CRISPR Gene Dependency	1.0	2.30365
prethalamic eminence	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46274
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73436
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875882
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.896662
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45794
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40693
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46402
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.116
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23576
GTEX-P4PQ-0526-SM-2HMKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847633
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BONNA-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF564	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84123
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63417
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16484
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
precuneus, left, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.952174
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58014
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96004
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K14875480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11378
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8495
SNU899	CCLE Cell Line Gene Mutation Profiles	1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.80822
BRD-K40841951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14296
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2457
BRD-K29908513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46146
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.72447
Macular Degeneration	dbGAP Gene-Trait Associations	1.0	0.258751
CRCGN015_MCF10A.WT.HP_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30051
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
DDRGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.471
NB1	DepMap CRISPR Gene Dependency	1.0	2.31899
NCI-H2196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845347
PMC4829974__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919764
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43246
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24814
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71946
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.4125
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51214
CEBPB	ENCODE Transcription Factor Targets	1.0	null
H2AB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58716
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06124
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27212
Medial geniculate complex, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13722
activation of mapkk activity	GO Biological Process Annotations 2015	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0925
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K04429417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92596
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01205
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4167
BRD-K47636083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35482
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00213
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WT-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06196
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14545
BRD-K99302735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08143
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6364
BRD-K13164804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07517
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10459
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73011
LRCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26642
ZNF736	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60448
PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K61432982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17691
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34184
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14528
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0341
J82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24374
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20752
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.854984
ING2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35527
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K60661821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81668
positive regulation of protein modification process	GO Biological Process Annotations 2015	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.034451
ZBED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24224
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84281
positive regulation of protein kinase activity	GO Biological Process Annotations 2015	1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77031
FAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97908
degeneration of macula and posterior pole	GWASdb SNP-Disease Associations	1.0	0.917442
GSE148252_2_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16867
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71615
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05543
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57787
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4067
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08819
LZTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77038
Lung squamous cell carcinoma_LUSC_TCGA-56-1622-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHTOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30003
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMBC2	CCLE Cell Line Gene Mutation Profiles	1.0	null
Prospore membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.523
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59112
BICR78	DepMap CRISPR Gene Dependency	1.0	2.26723
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937863
BRD-K67586245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01839
MDAMB231	DepMap CRISPR Gene Dependency	1.0	3.21551
CRCGN017_MCF10A.WT.HP_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32063
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48697
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29976
TM9SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34906
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28609
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14171
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3989
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57797
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17615
CEBPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47669
retinal degeneration	GWASdb SNP-Disease Associations	1.0	0.353983
RLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74771
MRPL44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55019
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11149
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03819
BRD-K20026212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56982
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1366
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LDAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07479
HEL-92.1.7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858836
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14569
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K98018160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60459
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82515
eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.63207
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85501
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78362
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28601
BRD-K37457040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34798
CRCGN011_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12165
ZSWIM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24251
HMOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36036
MAN1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7068
HPAFII	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78331
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55333
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10993
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF597	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02007
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.951723
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11876
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23343
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16459
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02382
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59476
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968656
CYP2D6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38298
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.859847
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41468
JL1	CCLE Cell Line Gene CNV Profiles	1.0	1.54399
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6571
MYDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01638
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57381
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.618
CNN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95195
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12623
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996808
TOR1AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07299
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67668
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03145
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04865
CRCGN008_HEPG2_24H:E15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01645
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KASUMI1	CCLE Cell Line Gene Expression Profiles	1.0	1.64782
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH292	DepMap CRISPR Gene Dependency	1.0	2.78541
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPP1CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97212
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40446
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-x_LPS-BMDCs-mouse_kinase_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40443
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50494
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4635
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847901
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1888
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.00217
ZNF274	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18775
HCC1954	CCLE Cell Line Gene Mutation Profiles	1.0	null
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43436
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60802
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888189
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.8
BRD-K73227539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67986
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10382
neuropeptide-S nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39199
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1381
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51681
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DHX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3872
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89247
NUDT17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80407
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14349
PSEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42544
BRD-K31218318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85313
NPPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09419
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0659
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0397
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEAS-2B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895742
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938019
SYVN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98884
EIF4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65988
paget's disease of bone	GWASdb SNP-Disease Associations	1.0	0.797385
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917025
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30832
BRD-K19411393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58243
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45537
BRD-K87929769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48367
NCIH2126	DepMap CRISPR Gene Dependency	1.0	2.88979
corneal disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.63207
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBC1D7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80365
HNF4A	ChEA Transcription Factor Targets	1.0	null
LHX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03187
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37949
CRCGN013_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10309
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50388
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.92722
BRD-K97086564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09663
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0609
KIRREL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95846
CIDEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46264
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K40474424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82547
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.967996
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6847
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.258
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969115
CDYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38166
SNGM	CCLE Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.050706
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	2.59981
ZNF660	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34856
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38258
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5885
PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49786
RND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41517
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0288
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0123
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06847
Perturb_1122_KD_E2APBX1_SRP115954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.75938
STRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08574
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.70968
BRD-K16588281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00895
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Keratoconus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99543
TRDMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36396
CCDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06251
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22924
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56087
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19711
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79998
KATNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37009
BRD-K78211834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21958
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90523
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
BRD-K56616847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32512
BRD-K72213294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28401
LARP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94568
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARMCX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0186
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	3.03932
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09811
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5558
EVSAT	CCLE Cell Line Gene Expression Profiles	1.0	1.7841
BRD-K45520793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10395
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.86965
NFKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63827
BTN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56037
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MHH-PREB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04059
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19986
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14284
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9513
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06858
ITPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50531
CASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13087
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31298
MAP1LC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4279
TLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54787
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02944
BRD-K29684372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51182
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3267
Superior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15594
KMS28BM	CCLE Cell Line Gene Expression Profiles	1.0	2.47514
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
r4 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06815
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0197
BTBD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83057
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00308
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69298
MYOCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3963
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEC108	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09161
BRD-K49573242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29363
BRI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44594
PPP1R2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.663
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-01A-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12032
BRD-K30821056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02021
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1733
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6863
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0413
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52398
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09733
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43983
BRD-K07011015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06039
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16304302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40409
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986216
SEL1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11768
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92282
SLC43A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77258
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06304
Lung epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
CA46	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11903614-11033_2025_10367_MOESM3_ESM.xlsx-Sheet1-Pharmacological_inhibition_of_the_Janus_Kinases_enhances_ASCL1_protein_stability_and_transcriptional_activity_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88714
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53232
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31356
MAPK cascade	GO Biological Process Annotations 2025	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1202
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5346
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71467
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3579
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6094
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77099
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33492
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K96737756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36737
BRD-K96547094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56894
GSE85874_4_v_5_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32370845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17689
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944384
BRD-K86722849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56106
TCEAL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51415
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00694
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916884
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85465
abamectin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60278
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23293
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
Perturb_1181_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.08903
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71529
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55461
SULT4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11833
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.53177
BRD-K96637326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22803
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.95904
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
SPAG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14423
EW7	DepMap CRISPR Gene Dependency	1.0	2.27312
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12003903-41531_2025_933_MOESM1_ESM.pdf-11-ENSG00000275111_ZNF2	Rummagene Transcription Factor Associations 2026	1.0	null
HT144	DepMap CRISPR Gene Dependency	1.0	4.22563
SIRNA_EIF4GI	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
NCIH1568	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62621
GCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01919
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95905
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977168
Lung squamous cell carcinoma_LUSC_TCGA-56-7823-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CARF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47477
proxyphylline-3115	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.956
RPL26L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20401
mapk cascade	GO Biological Process Annotations 2015	1.0	null
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
signal transduction by phosphorylation	GO Biological Process Annotations 2015	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929084
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65579
SREBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8847
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21312
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4605-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AIF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74301
PEDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65268
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6927
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1525
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03254
HOXC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81565
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946032
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14695
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47316
BRD-K16769896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32393
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
CHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36837
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32694
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98538
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2636
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.503
AMO1	CCLE Cell Line Gene Expression Profiles	1.0	1.47521
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MFGE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50723
CFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35467
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00298
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24489
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
SIPA1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73039
MONO-MAC-6	GDSC Cell Line Gene Expression Profiles	-1.0	-2.42854
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1295
HT3	DepMap CRISPR Gene Dependency	1.0	3.67691
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1143
BRD-K95500387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22494
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07349
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59462
GSE193351_1_v_9_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBE2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41903
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99737
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62515
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0419
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44626
BRD-K91998226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04263
BRD-K57468571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2395
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON	Rummagene Transcription Factor Associations 2026	1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.087396
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15956
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.87291
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61639
FLT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12507
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90931
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_6_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67386
SDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29038
mrc9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
SNU81	CCLE Cell Line Gene Mutation Profiles	1.0	null
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5532
ZNF48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93455
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3518
BRD-K55393423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24346
CLSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41164
lung	HPA Tissue Gene Expression Profiles	1.0	1.19547
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.888967
EBC1	DepMap CRISPR Gene Dependency	1.0	5.40848
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67931
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2268
Protein kinase-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50099
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10931
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33012
PUS7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8546
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98994
BRD-K94751306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44203
ZNF589	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.693425
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03145
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37825
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860574
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42456
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48445
BRD-K06398048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32847
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12323
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11108
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71262
BRD-K55218521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55323
U-266	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44878
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
BRD-A51540388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20116
BRD-K57173429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13028
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22968
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1293
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946032
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ZFP36L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55757
J82	CCLE Cell Line Gene Mutation Profiles	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH526	CCLE Cell Line Gene Mutation Profiles	1.0	null
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65865
GAMG	DepMap CRISPR Gene Dependency	1.0	2.07009
NCI-H2291	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21606
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907069
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99516
Perturb_11740_KO_Trp53_SRP221563	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.0015
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8795
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74306
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
bone remodeling disease	GWASdb SNP-Disease Associations	1.0	0.388281
PMC12003903-41531_2025_933_MOESM1_ESM.pdf-11-ZNF2_ZNF2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L1236	CCLE Cell Line Gene Mutation Profiles	1.0	null
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78447
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65745
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-w_SRPK2-KD-kinase_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50418
L540	CCLE Cell Line Gene CNV Profiles	1.0	1.38116
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997191
BRD-K81082554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51014
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.49278
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
eye and adnexa disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.63207
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881666
BRD-K54198678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75944
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21566
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32511780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17215
NBDY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31018
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.112205
GSE196407_1_v_0_fluorouracil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
Wsunhl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52067
NIF3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76679
NCIH2030	DepMap CRISPR Gene Dependency	1.0	2.59753
HPAF-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KY-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estradiol_oncorhynchus mykiss_gpl2096_gse5643	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71059
GJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49652
TUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94969
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41177
RAB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46453
HSPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48875
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49934
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59217
ART5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40507
Lateral terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30128
BRD-K27610371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83425
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7696
NCIH2286	CCLE Cell Line Gene Expression Profiles	1.0	1.43095
BRD-K22039769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09097
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PL4	DepMap CRISPR Gene Dependency	1.0	4.03202
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16946
BRD-K60052521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85017
GLYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46262
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09855
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01365
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89837874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11296
STON1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13697
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1453
USP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85239
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54924
positive regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65552
TGW	GDSC Cell Line Gene Expression Profiles	1.0	1.77004
Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.24439
RI1	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K83872468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70391
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52042
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02338
POLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74373
RD	CCLE Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01836
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78915
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
layer 5 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09506
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968656
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874799
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9913
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70209
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.852806
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37663
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86041
SARS-BatSRBD_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.57675
BRD-K86008496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09731
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46827
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8124
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28512751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12287
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64611
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV-90 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
TP53INP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4926
KYAE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1734	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85313
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K08927194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50829
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16387
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97257
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79765
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GPR173	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59446
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29176
Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
actin filament-based process	GO Biological Process Annotations 2015	1.0	null
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
ECC12	CCLE Cell Line Gene Mutation Profiles	1.0	null
TT	CCLE Cell Line Gene CNV Profiles	1.0	2.37286
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
transferase activity	GO Molecular Function Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A48L-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60619
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	1.77623
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23392
DHX57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67382
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82251
ISHIKAWAHERAKLIO02ER	CCLE Cell Line Gene Mutation Profiles	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.861221
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976118
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16287
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8582
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02506
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946032
CRCGN017_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89475
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06337
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77933
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
ascospore-type prospore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24378
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20816
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02369
Prostate adenocarcinoma_PRAD_TCGA-HC-7231-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24435
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8223
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
phosphate-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07817
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6399
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95193
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.35917
hsa-miR-491-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K96758498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07413
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8554
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11672
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90307
LNZTA3WT4	DepMap CRISPR Gene Dependency	1.0	3.84247
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64087
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00038
protein serine/threonine kinase activity	GO Molecular Function Annotations 2015	1.0	null
T98G	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K84077642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74739
Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G402	CCLE Cell Line Gene CNV Profiles	1.0	1.53369
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL851	CCLE Cell Line Gene Expression Profiles	-1.0	-2.6817
BRD-K46308702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26734
intracellular signaling cassette	GO Biological Process Annotations 2025	1.0	null
JEKO1	CCLE Cell Line Gene Mutation Profiles	1.0	null
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22303
CNIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9102
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.096
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12962
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7524
PLCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11083
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62265
BRD-A26952628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1409
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10868
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.852479
BRD-K87779720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04267
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16228
Serine/threonine/dual specificity protein kinase, catalytic  domain	InterPro Predicted Protein Domain Annotations	1.0	null
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.205
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74862
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19045
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20543
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05563
hsa-miR-4680-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ZFAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37382
GTEX-REY6-2126-SM-48FD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942278
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01004
CRCGN015_HEPG2_48H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08731
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.51264
BRD-K38519440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21246
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94394
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11009
TMEM181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03732
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83190598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00027
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69369
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61696
BRD-K13118417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78714
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57424
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1224
positive regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61236
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889377
MLMA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24498
Malignant Transformation	DisGeNET Gene-Phenotype Associations	1.0	null
JRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.2984
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC4829974__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_15286_KO_Trp73_SRP067006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.51869
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1543
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15876
JHOC5	CCLE Cell Line Gene CNV Profiles	1.0	2.12751
FAM47E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55024
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976084
CDC42SE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33897
EEF1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47438
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.6611
BRD-K07276273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01342
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3323
ADAM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24819
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12115
CW2	CCLE Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8443-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30863464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17965
KIJK	CCLE Cell Line Gene Expression Profiles	1.0	1.56956
SURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41019
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
639V	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44346
BRD-K19752998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0837
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40799
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3611
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29831
BRD-K90136643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2386
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2005
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98648
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32879
ABHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90799
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22352
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86597
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01177
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861509
Medial geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33788
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
RYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83938
ZIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44636
BRD-M97109212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02046
BRD-K21996189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04911
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.25746
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73927
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02719
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27252
GSE229978_4_v_7_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55154
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53356
G361	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE214685_0_v_1_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70361
LIPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34675
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE209680,GSE209683_0_v_1_nfat5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7473-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03293
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29031
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1925
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87587
CRCGN016_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2714
regulation of mapk cascade	GO Biological Process Annotations 2015	1.0	null
EFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95468
METTL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3098
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.02315
Perturb_4823_KD_Chd4_SRP315519	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.72566
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16156
BRD-K09863466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08526
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93434
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14065
KMS34	CCLE Cell Line Gene Expression Profiles	1.0	2.17757
ZNF526	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33321
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28168
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41254
BRD-K62318087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10144
SUM190PT	DepMap CRISPR Gene Dependency	1.0	3.2979
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11643
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19116
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845561
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19112
BRD-K19662956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41481
BRD-K31577322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23582
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36727
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04707
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.40062
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03883
CFAP418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59753
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23756
eye disease	GWASdb SNP-Disease Associations	1.0	0.136474
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33717
dorsolateral isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17515
BRD-K34519313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08126
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7429
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8785
BRD-K02844551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40577
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAKI1	CCLE Cell Line Gene Expression Profiles	1.0	1.89562
RBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92662
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99882
RERFLCMS	CCLE Cell Line Gene Mutation Profiles	1.0	null
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49361
ALMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21399
BRD-K70594121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20217
2313287	CCLE Cell Line Gene Mutation Profiles	1.0	null
BEND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39567
BRD-K39185798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4351
AACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48736
ROS-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13262
SARS-CoV_48Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.22695
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00825
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21599
BRD-K57586808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51828
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50495
Childhood Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K43364707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29358
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1993
LLPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64776
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.55712
TMEM51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02219
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.36675
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43361
BRD-K64704925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39561
CEP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12064
BE2-M17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17538
SNU886	CCLE Cell Line Gene Mutation Profiles	1.0	null
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92675
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21454
MRPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5755
CXCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52706
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48323
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94482
ZNF304	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74218
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TENT4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97493
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76681
PMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9132
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60788
BRD-K92241728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06792
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86488
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92403
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49158
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5948
PHF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
A549	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86904
SDR39U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52272
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23293
BRD-K16605233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34857
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9995
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06378
NCIH2023	CCLE Cell Line Gene CNV Profiles	1.0	1.66403
HEC251	CCLE Cell Line Gene Mutation Profiles	1.0	null
RHNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33069
BRD-K28329571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32851
mexiletine-3973	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Corneal Topography	DisGeNET Gene-Phenotype Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81692
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70098
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978007
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.438
RS5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94649
PLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47913
BRD-K30013451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30583
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
GTEX-WY7C-0426-SM-3NB3C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18292
CRCGN008_HEPG2_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16205
phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
TXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82028
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6489
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86212
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.526
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO680N	DepMap CRISPR Gene Dependency	1.0	2.51837
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37243
Bronchial epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.395
PRR15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24883
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968656
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83028
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K77139764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48495
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08273
superior parietal lobule, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839702
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18304
RASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65596
BRD-K94303022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69002
NCI-H1693	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47618
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46914
BRD-K92269212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76309
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33565
BRD-K19036695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2636
SREK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
TMEM60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89422
HMGXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66907
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20874
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
BRD-A63704386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39819
endometrium	HPA Tissue Gene Expression Profiles	1.0	0.993307
PTK7_knockdown_185_GSE50138	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.5724
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3673
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47332
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51362
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42044
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13965
H2591	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6153
NCIH1563	CCLE Cell Line Gene CNV Profiles	1.0	1.80105
Perturb_6165_KO_Tet2/Tet3_SRP060364	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.79535
SMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61191
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.616
HS821T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08141
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
GSK3A_KD_GDS4305_182_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.25189
INPP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35425
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.63207
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.364
C2CD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27302
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02902
clenbuterol-5266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBFOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79902
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33353
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05543
SPTBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20678
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1494
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58217
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88869
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2337
PRDM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57811
TTC38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.501
fusaric acid-3986	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A_48H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.796
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79252
GPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46736
Mesothelioma_MESO_TCGA-TS-A7P0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of transferase activity	GO Biological Process Annotations 2015	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8873
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35737
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.841519
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56424
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29269
TRIP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84277
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.59798
SYNDIG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61782
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23892
RNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71105
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03531
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8256-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90697693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72939
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61024
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55973
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35975
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50243
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836394
BRD-K30761927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10936
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
Bronchial epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.333
PEX11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72484
BRD-K88802328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27295
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9757
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55598
BEST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97602
EI24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66064
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48018
FRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64051
CRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12108
Adult Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
TPMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57224
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91048
BRD-K92569554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33844
HCT116	CCLE Cell Line Gene Mutation Profiles	1.0	null
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15428
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08343
TNRC6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42013
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78407
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41711
LRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41948
NCIH226	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5894
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47212522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90741
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.929293
BRD-K82216975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52842
CAMK2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87096
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6407
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.15446
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.80782
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14407
BRCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52531
CDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39605
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9151
BRD-K72356321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69872
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18213
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04531886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13093
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K59984972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71211
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52207
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A23345137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30928
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2269
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70258
APOBEC3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37142
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9467
PARD6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94278
UBAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8467
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6321
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90611
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859212
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27451
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32824
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27067
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04157
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.097
BRD-K01022714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16316
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07719
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14796
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1179_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.3481
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8554
isthmic liminal part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01692
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S11_DGEA_CDKN2A_PAX5-Supplemental_Table_11_Differentially_expressed_genes_between_CDKN2A_PAX5_and_all_other_subcluster_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
IGFBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04802
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.913377
BRD-K51461946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49641
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05352
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888189
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5698
SLVL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K34703146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01232
RPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01296
GSE146074_1_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04117
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.32805
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-w_SRPK2-KD-mouse_kinase_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BNL CL.2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
BRD-K86453556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84262
BRD-K63212062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60241
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.9406
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LGALS3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87177
BRD-K98598055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4313
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28707
C2orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87266
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5798
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
RERF-LC-MS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NUDT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95203
OCILY19	DepMap CRISPR Gene Dependency	1.0	2.60047
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2227	GDSC Cell Line Gene Expression Profiles	1.0	1.63609
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852918
BRD-K77808555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04667
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07493
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03404
SCC25	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66646
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
GSE242167_1_v_2_cd40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2039
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14619
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72999
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05326
DSH1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87622
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37195
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3472
GSE201042_2_v_1_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07319
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28329
macular degeneration	GWASdb SNP-Disease Associations	1.0	0.917442
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893158
GRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58553
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75204
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93918_1_v_3_clozapine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
697	CCLE Cell Line Gene Expression Profiles	1.0	1.41482
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2167
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13165
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24672
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6637
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44599
BRD-K84707727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13863
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3205
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22749
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16899
regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68259
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61431
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3731
OVK18	CCLE Cell Line Gene Mutation Profiles	1.0	null
SJSA1	CCLE Cell Line Gene Mutation Profiles	1.0	null
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900724
layer 6 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47381
MKN74	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95517
molecular_function	GO Molecular Function Annotations 2015	1.0	null
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11787
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5607
GALE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50989
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.565485
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888189
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52131
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
USP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27752
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7115
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24944
Perturb_644_OE_ERG_SRP344038	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.21153
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38837
HEC1A	CCLE Cell Line Gene CNV Profiles	1.0	1.39523
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2644
Sarcoma_SARC_TCGA-JV-A5VF-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.52611
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM35	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5228
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6359
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2665
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28024
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5243
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2291	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8242
BXPC3	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K21997380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55946
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60481
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23292
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4184
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06005
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899992
BRD-K69903198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72255
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839415
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01442
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19766
Acute Myeloid Leukemia_LAML_TCGA-AB-2967-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5275
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.205
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.03486
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66596
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-T_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38853
SNURF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89246
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12654
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42727
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.89634
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.96387
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4228
SLC2A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95496
PLSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32771
PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0383
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861779
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74611
CCNYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34759
TGM2_KD_GSE23702_713_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11908
KMS26	CCLE Cell Line Gene Expression Profiles	1.0	1.36126
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26114
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19967
BRD-K79709959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23452
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
Subthalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1353
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29456
FOXE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0243
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68926
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51139
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70038
HLFA	CCLE Cell Line Gene Mutation Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PALB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3664
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44724
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
LN428	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86318
BL70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71003
single-organism process	GO Biological Process Annotations 2015	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SAMHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9993
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02859
BRD-K02190643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47802
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.64838
PLAAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6358
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27443
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ES5	DepMap CRISPR Gene Dependency	1.0	2.86305
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84448
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXB13-26457646-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04624
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85441584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1936
ZZEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0377
layer 3 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12465
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WWC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67985
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05429
HEATR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7416
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895656
FEM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62015
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21712
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LUDLU1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54111
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04775
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977743
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829692
TBP	ENCODE Transcription Factor Targets	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55289
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84577
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3755
Perturb_13653_KD_CELSR2_SRP149837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.71922
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_8513_KO_Setd1b_SRP328849	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.04124
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7641
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PIPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6798
EDARADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95107
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04357
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.855864
BRD-K15160749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40928
disease	GWASdb SNP-Disease Associations	1.0	0.03436
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
NCOA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47413
SNU719	CCLE Cell Line Gene Mutation Profiles	1.0	null
TAF5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03037
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15134
ZKSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84941
BRD-K97733472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14927
sublayer 6a of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24199
receptor signaling protein activity	GO Molecular Function Annotations 2015	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4433
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15396
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.217517
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35979
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.825346
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23469
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04458
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881527
BRD-K93040255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44315
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3137
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C3A	CCLE Cell Line Gene CNV Profiles	1.0	1.3677
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50713
RD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.94542
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866257
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904123
SET2	CCLE Cell Line Gene Mutation Profiles	1.0	null
regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K69826976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21168
Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32433
BRD-K48029682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14502
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56805
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41864
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946032
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53299
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9349
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01334
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3201
Perturb_17304_KO_Tug1_SRP176442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58098
PLEKHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61394
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43391
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75627
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55333
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51426
HCC1569	CCLE Cell Line Gene Mutation Profiles	1.0	null
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35116
BRD-K08123827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33348
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.2223
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96362
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47199
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5786
MFE319	DepMap CRISPR Gene Dependency	1.0	3.18815
NFYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86468
GINM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.453
Presubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20602
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.61691
UMUC9	DepMap CRISPR Gene Dependency	1.0	8.23608
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53162
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2274
GSE132759_4_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10135449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00179
LMX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52934
LMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26779
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3116
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888189
GSE163282_12_v_5_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-61	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZM-226600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01792
BRD-K73524144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47107
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04946
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91695
Anteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3843
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m2 part of substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00955
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01472
PAQR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31784
ZNF343	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92054
RIMKLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82545
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46914
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21176
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968656
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2429
DLX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66196
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.19005
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9373
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93405
SERINC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01383
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22749
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01224
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HSC3	CCLE Cell Line Gene Mutation Profiles	1.0	null
Fine root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
BRD-K88016677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11402
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
TNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07636
BRD-K47998973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41538
GSE220813_0_v_1_zfp750_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DU145	DepMap CRISPR Gene Dependency	1.0	4.15493
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00825
HOXB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5376
CHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63885
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99633
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58902
dorsal part of alar p3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46274
signal transduction	GO Biological Process Annotations 2015	1.0	null
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60364
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28849
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
CRCGN011_HEPG2_24H:F06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03915
BRD-K97276563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30259
ZXDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34383
transferase activity, transferring phosphorus-containing groups	GO Molecular Function Annotations 2015	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828996
sublayer 6b of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41217
Sarcoma_SARC_TCGA-DX-A48J-01A-21R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VKORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69721
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72746
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN014_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47484
CLOCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
BRD-K13350372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87877
BRD-K00909602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6809
LIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64045
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38324
NCIH1436	CCLE Cell Line Gene Mutation Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880399
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73342
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13516
alpha-ergocryptine-4552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43355
Perturb_15080_KD_Chd8_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.8561
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39762
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1451
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06444
cellular component organization	GO Biological Process Annotations 2015	1.0	null
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13896
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.077416
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DQX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37902
actin cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
22RV1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07692
biological regulation	GO Biological Process Annotations 2015	1.0	null
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.29514
KIF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96801
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22216
NCIH146	CCLE Cell Line Gene Mutation Profiles	1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61934
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
SNUC5	CCLE Cell Line Gene Mutation Profiles	1.0	null
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41804
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69356
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913057
NOP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46622
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17624
BRD-K82521348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09971
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850613
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24909
Optic disk drusen	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43346
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942808
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21189
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905576
EM2	DepMap CRISPR Gene Dependency	1.0	3.0328
BRD-K58333451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03458
BRD-K25065206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78291
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4595
SCAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85093
BRD-K09117810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1978
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81423
BRD-K79213964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03057
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
Nuclear RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.598
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38463
RAB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43168
Prostate adenocarcinoma_PRAD_TCGA-CH-5766-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMCUB1	DepMap CRISPR Gene Dependency	1.0	2.23103
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1299
BCL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58
BRD-K39087188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75204
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44159
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888189
BRD-K49666076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39918
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74926
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
ZDHHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31269
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14415
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9172
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05596
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45916
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42377
OAW42	CCLE Cell Line Gene Expression Profiles	1.0	1.49337
BRD-K00507184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0065
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01755
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0403
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13464
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2585
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.79275
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	2.11672
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5344
nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.63207
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95352
LP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41918
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55276
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991699
macular degeneration	GAD Gene-Disease Associations	1.0	null
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970781
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3404
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55829
accessory entopeduncular nucleus (post-migratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87404
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5414
Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22407
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1632
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HACD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56466
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53770426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16181
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42631
NCIH838	CCLE Cell Line Gene CNV Profiles	1.0	1.34329
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75282
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	2.54494
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88631
BRD-K30895360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48513
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29674
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50396
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.87195
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3038
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
ST486	CCLE Cell Line Gene Expression Profiles	1.0	2.67965
SPCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7594
PMC8494348-pone.0257161.s002.xlsx-only_OXT_NOT_ext-OXT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2825
MHH-NB-11	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49161
SERINC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92682
BRD-K77953978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85363
YBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16762
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85093
SKOV3	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.860381
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32608
BRD-K33752391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05596
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22014
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82379643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46485
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	2.15535
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84623
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10068
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.49398
PMC10140619-mmc5.xlsx-Beta3_ConVsBSL-Gene_BHLHE22	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1777
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880399
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65753
BRD-K51681402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12827
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26681
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60695
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02818
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10807
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19707
SOX10_KO_GDS3480_257_rat_Schwannoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DDAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.388
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53154
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26597
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43495
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.134056
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20319
ARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74575
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34789
AFDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46391
CRCGN014_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2743
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21438
COMPOUND 1 [PMID: 24793884]	DGIdb Drug Targets 2026	1.0	6.6165
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90244
LCLC97TM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54079
PABPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81414
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.608
Brain Lower Grade Glioma_LGG_TCGA-HT-7611-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28008
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91428
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.25
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6972
CNPY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38773
HEY	DepMap CRISPR Gene Dependency	1.0	4.91293
LDLRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38617
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26004
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885894
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976829
PKNOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56328
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909443
USP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18782
activation of protein kinase activity	GO Biological Process Annotations 2015	1.0	null
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
OCILY3	CCLE Cell Line Gene Expression Profiles	1.0	1.94509
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.58565
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.116
BRD-K62794454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6591
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67902
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68591
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938019
16912175-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84846
EZH2	ENCODE Transcription Factor Targets	1.0	null
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60112
CALU6	DepMap CRISPR Gene Dependency	1.0	3.37196
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1591
Breast fibrocystic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.783
GOTO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54571
RBM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60138
BRD-K15714771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10778
RAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2949
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NDUFV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52893
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
A204	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
NAA60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49021
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
CYB5RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39249
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.099331
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.958096
BRD-K16663346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49703
BRD-K16698502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30838
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50713
HCC1806	CCLE Cell Line Gene Expression Profiles	-1.0	-2.58908
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03569
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26594
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
flumetasone-4272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU-475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.869723
MCAS	CCLE Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06759
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888189
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843894
CUL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23198
PL21	CCLE Cell Line Gene Mutation Profiles	1.0	null
CRIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59414
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25459
JHUEM7	CCLE Cell Line Gene Mutation Profiles	1.0	null
MRPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38787
MLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86597
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80087
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68956
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14683
ZNF516	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27076
COLO668	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49307
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37902
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05678
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0036
JPH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40401
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02826
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6056
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908427
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.321
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08466
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46184
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87806
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22533
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826321
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59745
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46827
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
KCNF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59989
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7256
icSARS CoV_72Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.46373
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0376
positive regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
ZNF484	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49019
positive regulation of mapk cascade	GO Biological Process Annotations 2015	1.0	null
posterobasal nucleus, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32817
BMAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31224
CA9-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75988
ctnnb1_21565795_adrenocortical_adenomas_lof_mouse_gpl570_gds3912	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.511221
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9348
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9257
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0264
BRD-K85636571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06353
PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30507
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57218
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09329
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01409
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932239
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72923
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.968202
STS-0421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3929
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.849
ICC15	DepMap CRISPR Gene Dependency	1.0	4.49019
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93901
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58067
intermediate stratum of PHyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28184
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
INPP5J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52184
Alveolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59125
BRD-K49215584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00008
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34957
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43182
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11375
MFE296	CCLE Cell Line Gene Mutation Profiles	1.0	null
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30186
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04225
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82264
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941493
NCI-H226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2937
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42693
CI1	CCLE Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945487
GTEX-S341-0826-SM-4AD73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939091
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00506
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919982
BRD-K93374700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08255
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71501
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10934
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ENPP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69759
PPM1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76344
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.52019
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24783
kinase activity	GO Molecular Function Annotations 2015	1.0	null
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06098
Apocrine adenosis of breast	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.318
GLO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89491
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.16086
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.60243
Mpk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
BRD-K79437066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50412
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20512
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8865
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1366
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
COLO783	CCLE Cell Line Gene Mutation Profiles	1.0	null
POLR2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90446
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88775
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17447
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40002
CEBPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07274
cellular process	GO Biological Process Annotations 2015	1.0	null
Superior olivary complex, periolivary region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15076
Neutrophilia	DisGeNET Gene-Disease Associations	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16459
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908578
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30388
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30403
Lung adenocarcinoma_LUAD_TCGA-97-7546-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YKG1	CCLE Cell Line Gene Mutation Profiles	1.0	null
KYO1	DepMap CRISPR Gene Dependency	1.0	6.51838
PDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82919
BRD-K48129913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.07271
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5761
Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K78574327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27051
BRD-K94346447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54488
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9931
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831904
BRD-K88150784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52073
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17087
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_7_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47555438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41845
RHOQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70372
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4305
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.863988
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61717
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80596
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11212
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.13063
J-RT3-T3-5	GDSC Cell Line Gene Expression Profiles	1.0	1.82297
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26242
debrisoquin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74787
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1581
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37723
JUN_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17486
Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33935
mantle zone of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46274
brain	GTEx Tissue Gene Expression Profiles	1.0	0.842787
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4573
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21319
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8215
FTC238	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63431
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68251
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
KARPAS299	CCLE Cell Line Gene Expression Profiles	1.0	1.88147
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.41244
BRD-A64761364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22224
regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K89537738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11681
Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07390518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15918
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44288
SMAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34207
BRD-K36324810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02176
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EPHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65462
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03294
BRD-K13038935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13327
HPAF-II	GDSC Cell Line Gene Expression Profiles	1.0	1.61263
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28769
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92933
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46276
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.86664
LMNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19457
RMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48836
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836859
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03549
BRD-K46298577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02507
Perturb_15734_KO_Kmt2d_SRP058264	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.18926
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.89135
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1931
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48558
SNU449	DepMap CRISPR Gene Dependency	1.0	5.34807
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8264
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08311
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9922
Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2091
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05352
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92931
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.856304
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23585
BRD-K43936610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31828
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562	BioGPS Cell Line Gene Expression Profiles	1.0	0.920631
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5584-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr2_135342903_A_G_b38	GTEx eQTL 2025	1.0	5.15761
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84174
MT-ND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80248
protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15126
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pneumonia	DisGeNET Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20P-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retinal disease	GWASdb SNP-Disease Associations	1.0	0.227112
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07901
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62097
Perturb_7092_KD_Lmna_SRP132471	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.85849
MSH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25366
U2-type spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5848
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.41281
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872845
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6002
BRD-K11987248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62586
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01951
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24184
GTEX-PWOO-0726-SM-2I3EB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09721
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69361
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05678
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	2.03623
BRD-K78668110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29338
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62739
cbp_cpb heterozygous mice_GSE30880_328_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.35131
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92393
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42928
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01146
BRD-K28559679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63675
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.163
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75636
ZNF239	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23365
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20755
NCIH1693	CCLE Cell Line Gene Mutation Profiles	1.0	null
KP1N	CCLE Cell Line Gene Mutation Profiles	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26289
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07187
PK45H	DepMap CRISPR Gene Dependency	1.0	3.43147
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29808
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6028
TMEM106A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2217
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90191
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885457
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22997
KLF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32199
OVCAR3	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.998609
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19532
Perturb_13655_KO_TAPR1_SRP291201	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.36276
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.18105
Protein kinase domain	InterPro Predicted Protein Domain Annotations	1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49934
BRD-K00676343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46807
AGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80399
positive regulation of signaling	GO Biological Process Annotations 2015	1.0	null
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32318
Perturb_15284_KO_Trp73_SRP067006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.0458
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H4-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
KYSE-520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WYJK-0826-SM-3NM8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947622
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869816
BRD-K23342427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88255
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27451
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1414
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00193
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24247
BRD-K06529600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07998
BRD-K22789469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22227
BRD-K05251963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39367
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67862892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15427
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GRB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6747
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0613
PDCD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46465
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.937467
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29493
ATXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7528
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900394
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72931
BRD-K92140823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02414
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3447
ZNF77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92851
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.40088
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32754
SRY	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K20377072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09919
BRD-K94697940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04406
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.75
NUDT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79688
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.108287
TUHR4TKB	DepMap CRISPR Gene Dependency	1.0	2.11801
BRD-K67409155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13739
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0739
COGN305	DepMap CRISPR Gene Dependency	1.0	2.88188
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1494
GSE254155_5_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
19808870-ST1	GeneSigDB Published Gene Signatures	1.0	null
HTATIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8938
SCAR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
precentral gyrus, left, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.953179
Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01329192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05848
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
C2CD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42816
BRD-K33272704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10059
BRD-K31589685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0498
BRD-K09975370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25676
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
lung	GTEx Tissue Gene Expression Profiles	1.0	1.10348
BRD-K72156149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24027
Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1475
BRD-A16119053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60625
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37217
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10606
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05978
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3924
layer 6 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26869
RAB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54239
SPG21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19667
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24924
GSE188382_2_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43319
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6667
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67335
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23892
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.882
BRD-K79324911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54316
STYXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93348
SBC5	CCLE Cell Line Gene CNV Profiles	1.0	1.91317
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28613
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0741
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04515
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18066
BRD-K73075421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49586
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
ASCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05557
cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27199
CHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37094
BRD-K98089885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0319
Lamina epithelialis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
EHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92793
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
POU5F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18283
T173	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53475
Corneal ectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
CLASRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93361
DNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29043
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60007
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19584
TMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2984
BRD-K95709431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03853
AATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51002
647V	CCLE Cell Line Gene CNV Profiles	-1.0	-3.12414
KMRC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	2.33929
phosphorylation	GO Biological Process Annotations 2015	1.0	null