association	dataset	threshold value	standardized value
Nucleus of Darkschewitsch	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10305
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.76878
abnormal neuron morphology	MPO Gene-Phenotype Associations	1.0	null
astroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232881
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	2.25374
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33249
dendritic	GeneRIF Biological Term Annotations	1.0	null
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.157
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.92821
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854393
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11968
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48027
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04597
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17464
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.17893
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33952
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7065-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.728
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perinuclear region of cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
IQGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88009
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63591
GSE100102_0_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4643	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
regulation of microtubule-based process	GO Biological Process Annotations 2023	1.0	null
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22759
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42935
blood protein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.10955
using	GeneRIF Biological Term Annotations	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.774419
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02663
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Motor Skills Disorders	CTD Gene-Disease Associations	1.0	1.0241
SOX2	ChEA Transcription Factor Targets	1.0	null
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.882
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8185471-mmc6.xlsx-up-_and_downregulated_genes-Day_6_SOX15-_-_upregulated_and_downregulated_genes_nearby_shared_FO_and_FC_regions_respectively_Related_to_Figure_6_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34044
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.91761
golgi apparatus	GO Cellular Component Annotations 2015	1.0	null
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039214
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07859
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microtubule cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
LCLC97TM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76069
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.968115
GSE70499_4_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cis-Golgi network	GO Cellular Component Annotations 2025	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057561
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5287
abnormal fear/anxiety-related behavior	MPO Gene-Phenotype Associations	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0646
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SP-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dehydration_Hypothalamus_GSE3110	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.15156
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.60444
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15512
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77267
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94872
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.893
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94253
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11475
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15384
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20349
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12469
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22053
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3619-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12865
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71436
hsa-miR-451b	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.134
SETD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2934
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27672
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14216
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
H4K20me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18269
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02005
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.951784
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31671
Perturb_1283_KD_TRIM26_ERP131496	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.3979
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45714
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	1.23805
Spinal Stenosis Of Lumbar Region	DisGeNET Gene-Disease Associations	1.0	null
Intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC11953091-12035_2025_4695_MOESM1_ESM.xlsx-s5-Supplementary_Table_5_Results_of_the_2-sample_pQTL_MR_on_insomnia_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62627
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06951
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88572
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065217
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1653
Alate adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38651
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
conformation	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10608
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1792
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.021
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.49056
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20138
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61351
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92913
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059897
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39713
Kidney Chromophobe_KICH_TCGA-KL-8343-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.3856
Perturb_13880_KD_MYCN_SRP073460	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.91645
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lysosome localization	GO Biological Process Annotations 2025	1.0	null
15073113-Table4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26987
YWHAB	Hub Proteins Protein-Protein Interactions	1.0	null
FHIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54986
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49974
b-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.074355
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
astroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066956
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.982599
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33877
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.520041
Perturb_820_OE_Rspo1_SRP325709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.191
localization	GO Biological Process Annotations 2015	1.0	null
cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41271
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85615
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53396
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56748
r4 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03146
cellular_component	GO Cellular Component Annotations 2015	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5304
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071414
abnormal sleep pattern	MGI Mouse Phenotype Associations 2023	1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
microtubule	GO Cellular Component Annotations 2023	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_SOX2_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.306
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828099
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47426
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09254
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863426
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal anxiety-related response	MPO Gene-Phenotype Associations	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.728
PMC8299217-mmc4.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11169
Perturb_6217_KO_Mef2d_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.8938
GSE202434,GSE202438_15_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4287	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.165
SP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09744
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GW-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08393
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926295
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
EXOSC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78429
BT-483	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73908
abnormal offspring retrieval	MPO Gene-Phenotype Associations	1.0	null
head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261624
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73945
hippocampus	HPA Tissue Protein Expression Profiles	1.0	0.953245
EDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67639
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952535
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960789
DNAJB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10748
HCV JFH1_96Hour-Huh7_5_1c2_None_GSE29889	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.40889
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Febrile Neutropenia	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-338-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
GSE146865,GSE146866_4_v_3_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.868266
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91479
parietal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.208533
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08208
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38069
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Megalencephalic leukoencephalopathy with subcortical cysts	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25251
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31254
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.537
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972119
GSTA4	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04119
AM38	Achilles Cell Line Gene Essentiality Profiles	1.0	1.37319
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975166
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1428
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94437
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.8507
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058176
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10052
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
MYOG	ENCODE Transcription Factor Targets	1.0	null
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40098
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4488	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC11495544-JPN-240026-at-2.pdf-122-ARNT2_1_ARNT2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4605-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1225
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831302
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22846
GSE178532_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.303781
WDR43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43085
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6905
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09591
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38869
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09254
PMC11555823-supplementaltable4_ddae135.xlsx-Sheet1-Genes_inversely_regulated_between_MDS_and_RTT_iNeurons_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
USHBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81358
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06866
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-936	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
A549	Achilles Cell Line Gene Essentiality Profiles	1.0	1.12462
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_EZH2-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832511
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0589
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47499
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.43837
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EPI-2269-1 (USO1)	NURSA Protein Complexes	1.0	null
TMEM234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94809
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
DPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03948
regulation of cytoskeleton organization	GO Biological Process Annotations 2023	1.0	null
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.828924
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.957298
GSE89018_11_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cardia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.629
RTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60533
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.91348
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16264
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_SOX2_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.83571
OCIMY7	DepMap CRISPR Gene Dependency	1.0	2.22522
ZNF263	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6216_KO_Mef2c_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1966
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99814
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal synaptic vesicle number	MPO Gene-Phenotype Associations	1.0	null
CORL105	DepMap CRISPR Gene Dependency	1.0	4.17729
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2972
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10426
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9903
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.31002
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58408
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22941
stereotypic behavior	MPO Gene-Phenotype Associations	1.0	null
Primary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0059
cellular component morphogenesis	GO Biological Process Annotations 2015	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.0137
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55674
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86271
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19613
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13071_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.03602
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32322
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16888
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.58713
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8797
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24486
PTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34031
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18669
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.99875
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.18524
GSE110178_4_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3908
Field CA2, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18673
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936727
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61288
GSE136869_1_v_0_lpar2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04319
GSE109111_2_v_0_stim1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34682
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02313
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39169
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.988114
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27434
RNF2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16555
JAG1_OE_GDS3571_40_human_endometrial stromal cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
megakaryocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.152081
Perturb_15726_KO_Il1rl1_SRP274117	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.02958
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84788
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHSY5Y	CCLE Cell Line Gene Expression Profiles	1.0	1.75951
DLG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71069
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
DFFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70991
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S13-Table_S13_MR_resluts_of_brain_pQTL_and_large-artery_atherosclerotic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30891
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.771835
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43282
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.961
Katanin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05419
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21388
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.900056
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21993
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.66813
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04266
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52662
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.15681
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.7188
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1212
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18181
structural	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00876
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913145
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203308_14_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129772_2_v_1_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Schizophrenia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Perturb_13937_KD_PHOX2B_SRP345639	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE181513_0_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05501
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10919
schizophrenia	GeneRIF Biological Term Annotations	1.0	null
Perturb_15779_KO_Nrl_SRP009096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3536
Lissencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889369
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0793
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_949_KO_Bhlhe40|Bhlhe41_SRP216680	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17791
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990564
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6788
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.19351
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0307
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912625
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
Perturb_14567_KO_Got2_SRP348541	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.6452
CCND1	ChEA Transcription Factor Targets	1.0	null
mRNA_NANOG_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE114992,GSE114993_1_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898616
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94761
temporal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827996
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.88287
PHF8	ENCODE Transcription Factor Targets	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1039
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62675
Perturb_5881_OE_H3C1_SRP106792	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.58678
GSE112762,GSE112767_1_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228413_2_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cleft Lip	CTD Gene-Disease Associations	1.0	1.0189
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051565
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.444
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64414
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cis-Golgi network	GO Cellular Component Annotations 2023	1.0	null
MYC_Activation - 24 hours_GDS2025_726_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-520h	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22876
positive regulation of neurogenesis	GO Biological Process Annotations 2023	1.0	null
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27377
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43287
TADA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68617
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988504
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1215
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33634
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7712
RTN4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2335
CBC31 (POLDIP3)	NURSA Protein Complexes	1.0	null
GSE178255_3_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
Perturb_3820_KO_Satb2_SRP307573	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE166169_0_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1678
hsa-miR-3064-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-642b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56267
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62998
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
megakaryoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.141889
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.7557
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05047
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Giant cell tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5936
YDJC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2559
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05624
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42378
D-542MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2284
GSE100102_4_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of axonogenesis	GO Biological Process Annotations 2025	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00882
Perturb_4236_KD_Cnot7_SRP091584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.66981
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.999135
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08149
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051456
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0912
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	2.074
Agranular insular area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36151
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.04692
golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26329
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901812
USP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27799
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98278
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.291008
PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-219-IKZF1_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00383
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4314
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056266
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.242
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56835
ChIP_NANOG_18700969	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synaptic vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
ATM_Deficiency_GDS1544_769_mouse_Lymph nodes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
BT20	Achilles Cell Line Gene Essentiality Profiles	1.0	3.12345
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	1.7956
mumps	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.540829
KLF4	ChEA Transcription Factor Targets	1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887896
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.191
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73066
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06337
AKT1_OE_GDS2308[_473_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
crucial	GeneRIF Biological Term Annotations	1.0	null
CNOT3	ChEA Transcription Factor Targets	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.902707
PMC5830929-supp_gad.301887.117_Supplemental_Table_S3.xlsx-Sheet1-Downregulated_genes_in_CHD7-KD_and_CHARGE_NE_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7210-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S15-Table_S15_MR_resluts_of_brain_pQTL_and_small-vessel_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33291
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lysosomal lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.7
GSE210580_3_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38922
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21125
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36002
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05017
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5876_OE_Six1_SRP141174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.0701
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.842
PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Downregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924623
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60659
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849155
Perturb_16727_KO_Mbd2_SRP326773	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.01668
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	1.91813
myotonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.285086
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.746277
non-hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.439123
cell morphogenesis involved in neuron differentiation	GO Biological Process Annotations 2025	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S3.xlsx-Table_S3F-Supplemental_Table_S3F_ZFX_binding_pattern_clustering_information_for_genes_with_promoters_bound_by_ZFX_related_to_Figure_2I_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058917
BL990 (INCENP)	NURSA Protein Complexes	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32139
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1948
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EB-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38208
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24287
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CORL47	CCLE Cell Line Gene Expression Profiles	1.0	1.66749
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03336
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.08825
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15531
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10572
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34703
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ULK1_knockout_198_GSE60778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.48019
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.10739
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13359
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.211
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05845
MIXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31545
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03575
CAMA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72814
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19009
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946004
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08078
Perturb_11912_KD_Arntl2_SRP063609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.95924
neuron projection	GO Cellular Component Annotations 2025	1.0	null
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21717
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898727
C2BBE1	CCLE Cell Line Gene Expression Profiles	1.0	1.50683
Perturb_4326_KO_Zcchc8_SRP187429	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.30913
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17553
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09981
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902037
cellular	GeneRIF Biological Term Annotations	1.0	null
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25641
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40314
Ebolavirus(ZEBOV)_6day_PBMCs_rhAPCtreated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.8E-4
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6674
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.19479
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SOX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39192
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50674
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.00981
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83377
Perturb_463_KO_IGF2BP1_SRP251874	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.41407
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.97338
blood platelet disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.371847
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44638
TMEM209	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46974
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954552
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28082
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	2.31005
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14358
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23801
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.844997
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066634
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908739
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922531
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.47012
muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.106905
Laurin-Sandrow Syndrome	DisGeNET Gene-Disease Associations	1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.341
Rmz	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2427
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29683
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.711
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47547
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111102,GSE111105_3_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41684
Perturb_13815_KO_Rap1_SRP169501	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.90297
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08625
VMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21169
movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163729
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of axonogenesis	GO Biological Process Annotations 2025	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45715
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08781
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40572
GSE114258_3_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25954
CK1E	Kinase Library Serine Threonine Kinome Atlas	1.0	null
dendrite	GO Cellular Component Annotations 2023	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17789
GSE183113_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90887
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61236
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64045
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52614
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Caudoputamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06785
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07867
Anemia	DisGeNET Gene-Disease Associations	1.0	null
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.933
map6	GeneRIF Biological Term Annotations	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.16137
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887124
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tuberculous Pleural Effusion	DisGeNET Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23244
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060731
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.886023
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58727
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17617
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.43379
GSE144346_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OVISE	Achilles Cell Line Gene Essentiality Profiles	1.0	1.28165
hsa-miR-4455	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HSD3B7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10007
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19199
hsa-miR-761	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE137653_4_v_0_siglecf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75145
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78421
controlling	GeneRIF Biological Term Annotations	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01621
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.54664
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Downregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
Kinesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.429
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
Ataxia	CTD Gene-Disease Associations	1.0	1.01776
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
CHRAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83445
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042914
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC15A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44478
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.967573
BL596 (APTX)	NURSA Protein Complexes	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.09756
GSE112761,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
JUND	ENCODE Transcription Factor Targets	1.0	null
PMC3443648-1752-0509-6-89-S1.xls-Sheet1-NFYA_NFYA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845394
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
Cardia cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
CDC42BPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2456
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948667
CHD2	ENCODE Transcription Factor Targets	1.0	null
LN235	DepMap CRISPR Gene Dependency	1.0	2.15017
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.880561
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
SF3B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8072
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24269
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68536
HIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32764
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	2.12186
progressive supranuclear palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.387794
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99977
MEWO	CCLE Cell Line Gene CNV Profiles	1.0	1.58063
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929866
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61222
ME1	CCLE Cell Line Gene CNV Profiles	1.0	1.33556
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11227
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23614
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06996
NRL_Deficiency_GDS1693_239_mouse_Photoreceptors cells of retinas at 4 weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.34314
influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.221793
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ChIP_RNF2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17059
Learning Disorders	CTD Gene-Disease Associations	1.0	1.85869
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38033
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8795
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15561
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.838215
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39118
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12069
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07001
Atrophic gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
TCF3	ChEA Transcription Factor Targets	1.0	null
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42578
CASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03218
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27067
EXOSC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90188
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.172
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863213
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70329
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31432
ENTREP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19584
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1476
CL11	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87933
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28705
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.273696
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864419
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54152
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973885
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.68968
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63683
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24043
MCAD_KO_GDS4546_422_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
salivary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247719
17009876-tableS1a	GeneSigDB Published Gene Signatures	1.0	null
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35823
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35778
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40386
Chagas Disease	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843689
ARHGEF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38866
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2546
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ulcerative Colitis	DisGeNET Gene-Disease Associations	1.0	null
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123887,GSE123888_2_v_1_hpgd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0059
retrograde	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
DNA replication preinitiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dendrite	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ERBB2_druginhibition_6_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.20095
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138939_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75164
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.5118
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MOV10L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36432
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996497
PMC8481886-Table_1.xlsx-A_subsets-iMSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1724
Perturb_12673_KD_Mitf_SRP191908	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.84673
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824942
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.091
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
MRPS18C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23895
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874828
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.1558
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04656
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42465
non-hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062819
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93745
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34013
Perturb_13873_KD_ELF4_SRP182698	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.08427
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IOMMLEE	Achilles Cell Line Gene Essentiality Profiles	1.0	1.55097
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.89981
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76753
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CBC2232 (AKAP8)	NURSA Protein Complexes	1.0	null
NCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11211
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83411
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23396
hsa-miR-4419a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PAX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31428
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.929639
Perturb_13066_KD_Trim28/Setdb1_SRP073679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.45824
KCNK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44232
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26152
HSC4	CCLE Cell Line Gene CNV Profiles	1.0	1.67129
Autosomal recessive nonsyndromic deafness 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
PFSK1	DepMap CRISPR Gene Dependency	1.0	8.74228
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043714
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3724
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78144
BL5032 (CHD7)	NURSA Protein Complexes	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.03575
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17224
TRAPPC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11331
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24986
Perturb_421_KD_MYBL2_SRP239534	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.9818
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8722
microvascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126929
Severe Major Depression With Psychotic Features	DisGeNET Gene-Disease Associations	1.0	null
GB1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.36359
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.532
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.311
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.26516
Postoperative Delirium	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_15771_KO_Nrl_SRP219918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE169263_1_v_0_armc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cingulate gyrus, frontal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864196
GLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18663
GSE100102_0_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05338
RORB	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13188
Perturb_13364_KD_Wwtr1_SRP079400	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.22725
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.84824
Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.786468
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935741
organelle	GO Cellular Component Annotations 2015	1.0	null
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70051
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959094
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9665_KD_TCF4_SRP188467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07254
BL2264 (DOCK9)	NURSA Protein Complexes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_3_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
partial neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454512
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158834_2_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Agnosia	DisGeNET Gene-Disease Associations	1.0	null
MYB-21317192-ERMYB-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924623
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54873
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061346
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0291
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
tricuspid valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.143853
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NRL_Deficiency_GDS2936_630_mouse_Retinas - 10 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842647
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870045
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66338
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.2387
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848911
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
relapsing fever	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.856087
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31465
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52457
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31067
hsa-miR-4657	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Hyperphosphatasia with impaired intellectual development syndrome 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.882297
Perturb_15224_KD_lncRNALFAR1_SRP101771	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68199
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.72406
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.501909
Perturb_17379_KD_Pparg_SRP190223	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.60192
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28201
cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57173
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4708
Stereotypic Movement Disorder	DisGeNET Gene-Phenotype Associations	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44848
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17823
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85988
abnormality of circulating fibrinogen	GWASdb SNP-Phenotype Associations	1.0	0.58452
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30871
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39897
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.558622
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.352834
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04244
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47822
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.31506
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3832_KO_Foxd2_SRP307575	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.32943
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24302
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889803
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.387051
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12338_KD_TFEB_SRP226507	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.13824
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
PSIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66538
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5755
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.26208
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16867
SARS-CoV_84Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.59112
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43341
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19395
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972623
Perturb_7804_KO_Ythdc1_SRP065329	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.191
Perturb_13213_KO_Yap1_SRP059253	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.71721
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839841
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056902
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00423
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.741327
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZCCHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43423
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68536
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE410	DepMap CRISPR Gene Dependency	1.0	5.23671
Prediabetes Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5669_KD_Yy1_SRP281855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.1031
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16616
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.886998
SOX2-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32588
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
sbc2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71441
Perturb_15705_KO_Rnf20_SRP304263	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.2332
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.880078
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
hilus of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51478
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5694-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
akinesia	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_12674_KD_Sox10_SRP191908	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.18403
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954794
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.178
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.746381
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17794
Dentate gyrus, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85988
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16264
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27426
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3447
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05477
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58609
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.72948
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03336
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64338
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86037
ZNF281	ChEA Transcription Factor Targets	1.0	null
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71003
GSE229671,GSE229673_0_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.05206
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DJ-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microtubule binding	GO Molecular Function Annotations 2023	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15881
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	1.98955
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03336
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.306
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07674
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-600	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GPATCH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42968
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2663
atrial heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.480945
GSE228413_0_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00324
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1992
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57682
CORL51	CCLE Cell Line Gene Expression Profiles	1.0	1.37978
Mood Swings	DisGeNET Gene-Disease Associations	1.0	null
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23236
microtubule	GeneRIF Biological Term Annotations	1.0	null
MPP89	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06188
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830586
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864971
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33967
EZH2	ChEA Transcription Factor Targets	1.0	null
Pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64711
Abnormalities, Multiple	CTD Gene-Disease Associations	1.0	1.30208
GSE100102_4_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47877
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15564
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53959
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83812
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal synapse morphology	MPO Gene-Phenotype Associations	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46418
ESR1	ChEA Transcription Factor Targets	1.0	null
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
temperature	GeneRIF Biological Term Annotations	1.0	null
TE15	CCLE Cell Line Gene CNV Profiles	1.0	2.02137
Hyperphosphatasia with impaired intellectual development syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.48517
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8988166-EMMM-14-e14841-s007.docx-0-ASCL1_ChIp-seq_Augustyn_et_al_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.54101
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895252
network	GeneRIF Biological Term Annotations	1.0	null
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
CTAGE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9923
SKNDZ	CCLE Cell Line Gene Expression Profiles	1.0	1.86186
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01858
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12041165-401_2025_2886_MOESM1_ESM.xlsx-Meta_CAA_vs_AD-Genes_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316224
Hyperphosphatasia with impaired intellectual development syndrome 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
basis	GeneRIF Biological Term Annotations	1.0	null
PMC11563688-jci-134-173448-s017.xlsx-EC2-gene_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92389
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20295
COLO680N	DepMap CRISPR Gene Dependency	1.0	4.07514
NF2	MSigDB Cancer Gene Co-expression Modules	1.0	null
Golgi-associated vesicle	GO Cellular Component Annotations 2023	1.0	null
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KQ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11601945-jci-134-173770-s148.pdf-6-ENSG00000137309_HMGA1	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17464
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.54025
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68213
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970497
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4E-Supplemental_Table_S4E_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_MCF-7_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LN215	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.46438
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26439
PMC2866657-pone.0010547.s003.xls-ESE3_corr-Genes_correlated_anticorrelated_to_ESE3_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23068
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985777
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.163
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70051
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1826
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28423
cellular component organization	GO Biological Process Annotations 2015	1.0	null
TCF7	ChEA Transcription Factor Targets	1.0	null
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46611
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00358
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr11_75603742_G_T_b38	GTEx eQTL 2025	1.0	1.47954
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869766
Perturb_12694_KO_p75_SRP327861	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.53278
FKBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01459
VPS26C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44212
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83744
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46012
UPMD1	DepMap CRISPR Gene Dependency	1.0	2.40794
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.72384
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4118
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
UMUC16	DepMap CRISPR Gene Dependency	1.0	7.75478
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13402
CCC5	DepMap CRISPR Gene Dependency	1.0	3.56351
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46727
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20379
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7113
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25369
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57285
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077397
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.84678
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056912
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	1.34831
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.693832
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878001
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAP4K5_knockdown_199_GSE61497	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.42337
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25267
hsa-miR-548g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_7611_KD_PARP1_SRP410217	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952802
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HA1E	DepMap CRISPR Gene Dependency	1.0	2.73782
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-548a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4947
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16328
Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S117	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5831
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0713
Osteogenesis imperfecta type 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3061
GSE111035,GSE111040_8_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.76437
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932695
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32433
KELLY	CCLE Cell Line Gene Expression Profiles	1.0	1.36786
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19419
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00566
KYSE410	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27088
HGH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17012
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918528
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
BL6415 (BCR)	NURSA Protein Complexes	1.0	null
PMC7899452-media-5.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32898
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44127
abnormal synaptic plasticity	MPO Gene-Phenotype Associations	1.0	null
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56358
Perturb_17720_KO_Apoe/Ahcy_SRP342341	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.55658
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42348
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE176305_0_v_3_rotenone_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytoskeleton-dependent intracellular transport	GO Biological Process Annotations 2023	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3981
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42208
Weight Gain	CTD Gene-Disease Associations	1.0	1.01966
GSE96641_3_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918179
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30535
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998632
UBTF	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915273
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.84242
HCV_8week+IFN-a_None_GSE37715	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.0896
cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287803
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.942314
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01055
GSE169697,GSE169725_0_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3500769-srep00875-s3.xls-PAX2-Time_4_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133087_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dentate gyrus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62104
GSE211955_1_v_0_jmjd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45701
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891839
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.84678
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03707
CENPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82464
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29703
tick-borne relapsing fever	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.25124
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42918
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00903
Obstructive Sleep Apnea Hypopnea Syndrome	DisGeNET Gene-Disease Associations	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04299
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80658
EXOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05015
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3903
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.259
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05205
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-IE-A4EK-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postsynaptic specialization of symmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.392
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.53576
Neoplasms	CTD Gene-Disease Associations	1.0	1.13007
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1712
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51787
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	1.5189
Hereditary diffuse gastric cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
Varicosity	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.25
TNIK_knockdown_297_GSE17623	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.70526
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.633505
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40654
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08468
molecular layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76875
perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04051
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99591
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38907
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883949
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO21	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.23652
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
PLB985	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.0392
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058975
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908442
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50199
Perturb_431_KD_MYBL2_SRP371675	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.9818
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
neuron projection	GO Cellular Component Annotations 2023	1.0	null
NRL_Deficiency_GDS2936_631_mouse_Retinas - 2 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062901
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45186
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mucopolysaccharidosis type IIIB	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
Perturb_8947_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.06606
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57017
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61871
GSE139016_0_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
protein complex	GO Cellular Component Annotations 2015	1.0	null
SNU324	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13807
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910525
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.139252
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03468
Bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13999
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907441
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE114992,GSE114993_8_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21887
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17767_KO_Prdm16_SRP238935	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.77777
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12652
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06866
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
19377508-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27207
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE137137_1_v_0_rcor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30438
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25318
WDR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60464
PMC3500769-srep00875-s3.xls-GATA3-Time_4_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966854
hemorrhagic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.323002
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17764
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17891
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.48169
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16936
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral	GeneRIF Biological Term Annotations	1.0	null
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.00513
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26991
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
H3K36me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.34926
basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.140966
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27903
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17854
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00916
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31741
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056086
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884281
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.68507
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35178
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5584-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.525931
regulation of axonogenesis	GO Biological Process Annotations 2023	1.0	null
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848611
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.325552
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73438
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057689
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.92752
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EC-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.728
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68536
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALM1	MSigDB Cancer Gene Co-expression Modules	1.0	null
spectrometry	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05833
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.19279
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14140_KO_Chsy3_SRP250178	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.75314
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03756
ELF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32556
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04619
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35473
EIF4G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02295
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nes	HPA Cell Line Gene Expression Profiles	1.0	1.27421
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.046
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55486
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27706
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25545
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.987107
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.195183
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.68725
GSE153341_2_v_3_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BL3131 (PPP2CB)	NURSA Protein Complexes	1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	2.32139
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.622
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56555
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03377
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A23Z-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213410_0_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_2_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_2_Mesendoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21449
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.932337
vero cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233162
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849877
PTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17849
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.78818
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34989
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863652
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.35213
NCI-H322M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
18435859-ShorterGeneList	GeneSigDB Published Gene Signatures	1.0	null
Perturb_403_KO_FOXM1_SRP272209	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.86214
SUZ12_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25648
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.931245
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.7485
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09739
Perturb_16513_KD_C11orf53_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834464
LCLC103H	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
MYC	ENCODE Transcription Factor Targets	1.0	null
Perturb_3395_KO_Irf4_SRP028864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.5167
SOX9	ChEA Transcription Factor Targets	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.07549
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.17469
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053079
hsa-miR-346	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14251
GSE147366_3_v_0_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7598_KD_PARP1_SRP410217	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.146
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17464
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863652
GSE158834_0_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242199_2_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06533
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComUp-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947444
Microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.279
PMC12808183-41598_2025_31780_MOESM6_ESM.pdf-2-ATF3_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.65453
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.927997
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838614
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24453
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF648	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90654
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928436
Cerebral peduncle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.168
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Paroxysmal Atrial Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
increased anxiety-related response	MGI Mouse Phenotype Associations 2023	1.0	null
RBM8A	MSigDB Cancer Gene Co-expression Modules	1.0	null
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88412
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04013
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.952395
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02992
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.54884
PMC4595011-pgen.1005555.s003.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.186708
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab10_KDM5C-KD-up-DKD-rescued-Table_10_Up-regulated_genes_in_KDM5C-KD_and_rescued_genes_in_DKD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940959
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	1.17185
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00877
PMC12123029-41598_2025_3625_MOESM1_ESM.pdf-30-NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
Striatum dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06929
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92573
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF598	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40169
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92253
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10776
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24325
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	3.91508
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968638
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65665
SUM190PT	DepMap CRISPR Gene Dependency	1.0	3.96545
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
serve	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43475
E2F1	ChEA Transcription Factor Targets	1.0	null
EMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77019
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10356
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.757879
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_15490_KO_BCOR_SRP168753	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.42737
Acute Myeloid Leukemia_LAML_TCGA-AB-3001-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.850236
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44514
Site of polarized growth	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.4
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_24_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48368
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0912
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Embryo Loss	CTD Gene-Disease Associations	1.0	1.01025
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9971
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
SCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99171
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7238
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01025
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29545
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
E2F4	ChEA Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	1.0	null
MTF2	ChEA Transcription Factor Targets	1.0	null
RNASE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52407
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gingival cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62478
cytoskeleton-dependent intracellular transport	GO Biological Process Annotations 2025	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20564
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Transient Cerebral Ischemia	DisGeNET Gene-Disease Associations	1.0	null
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20521
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.845664
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1618	CCLE Cell Line Gene Expression Profiles	1.0	1.47199
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-TAL1-sequence_name_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12062214-41467_2025_59646_MOESM5_ESM.xlsx-HMGA2_activated_repressed-Ensembl_ID_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4467
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73555
neuron projection morphogenesis	GO Biological Process Annotations 2023	1.0	null
SNU1105	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.18196
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14385_KD_PAX8_SRP276625	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.1703
CORL95	CCLE Cell Line Gene Expression Profiles	1.0	1.43001
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13648
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31904
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
16651409-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158605
Sarcoma_SARC_TCGA-IW-A3M6-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946018
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41157
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18338247-SuppTable4B	GeneSigDB Published Gene Signatures	1.0	null
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2565
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00724
TAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11087
Perturb_15325_KO_Setd2_SRP251920	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82303
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of cell projection organization	GO Biological Process Annotations 2025	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896123
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28386
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.965361
Perturb_7604_KD_PARP1_SRP410217	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.74834
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7092
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054961
single-organism process	GO Biological Process Annotations 2015	1.0	null
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8238
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32226
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
MMADHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86918
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
Hyperphosphatasia with impaired intellectual development syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKMEL30	DepMap CRISPR Gene Dependency	1.0	3.20133
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31118
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.26029
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86782
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.31697
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	2.06234
ABHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16737
PMC6361956__F5	PFOCR Pathway Figure Associations 2023	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5322732__F6	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29426
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952253
MRPS18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28162
MRPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13138
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90227
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63752
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.3347
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.322
Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46332
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
TMEM14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81675
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44935
GSE115542_5_v_0_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064976
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13829
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181019
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE155162,GSE155169_1_v_3_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-2.66843
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-2.46788
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84541
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.532
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE134191_3_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_5_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMIM30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85866
hsa-miR-644	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.137442
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22066
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4559
Perturb_17773_OE_Tgfb1_SRP325964	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.60405
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.37741
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02627
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.582594
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03882
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	1.77403
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33559
hsa-miR-4717-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	1.0	1.50676
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
Microtubule minus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
Nmyc_OE_GDS2406_14_mouse_LUNG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
perinuclear region of cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14033
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.92146
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21997
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02187
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.191
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54893
TLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65833
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916493
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-663b	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052321
hsa-miR-1226	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20032
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6429
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40277
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09388
Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66291
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11179
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32941
NR2F1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11479
CIDEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10572
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2165
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02233
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.749999
EZH2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
microtubule	GO Cellular Component Annotations 2025	1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52297
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08682
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31177
NOMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
klf7_17123745_olfactory_epithelium_lof_mouse_gpl1261_gds2069	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.385046
resting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221989
periventricular stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4314
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4141
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6665
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25304
GSE159473_0_v_1_eif5a2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Field CA1, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22224
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
20937356-TableS2	GeneSigDB Published Gene Signatures	1.0	null
NCIH522	DepMap CRISPR Gene Dependency	1.0	2.78039
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.267
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1944
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926805
TBP	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78096
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8581
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.06
olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.195812
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGA2_KO_GSE55340_21_mouse_lung (E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1c-List_of_1682_genes_differentially_regulated_by_GLI1_FDR_0_1_GLI1	Rummagene Transcription Factor Associations 2026	1.0	null
HSOS1	DepMap CRISPR Gene Dependency	1.0	5.08521
mass	GeneRIF Biological Term Annotations	1.0	null
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_KLF4_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
oligodendroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.427254
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0184
PMC7064337-elife-51373-supp1.xlsx-SUZ12_targets_shPHF19-List_of_567_genes_marked_by_SUZ12_ChIPseq_iafter_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC33	CCLE Cell Line Gene Expression Profiles	1.0	1.41596
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4584
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63118
Perturb_13984_KO_Setd5_ERP110684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.76548
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC25A36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25371
GSE165647_6_v_7_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892717
PMC11237666-spectrum.03516-23-s0004.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190316,GSE190324_10_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33445
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hepatitis B	DisGeNET Gene-Disease Associations	1.0	null
cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.384451
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.578
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11459
Sto	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18793
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
Perturb_3970_Mut_BRAF_SRP258593	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.42746
axon	GO Cellular Component Annotations 2025	1.0	null
PANC0327	Achilles Cell Line Gene Essentiality Profiles	1.0	1.54952
SIMA	CCLE Cell Line Gene Expression Profiles	1.0	1.71537
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.082183
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942228
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Depressed Mood	DisGeNET Gene-Phenotype Associations	1.0	null
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HIVEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66818
WDR74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51042
LIN28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92717
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87675
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12430004-ugae028_Supplemental_File.pdf-9-IKZF3_IKZF3	Rummagene Transcription Factor Associations 2026	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.2536
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.726
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12132
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0081
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924623
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5414054-ncomms15013-s11.xlsx-SupplementaryData10-Supplementary_Data_10_Genes_differentially_expressed_due_to_infection_in_IRF5-_-_compared_to_parent_KOLF2_cells_IRF5	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF763	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91784
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02567
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47941
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9414
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18398
SIN3B	ChEA Transcription Factor Targets	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAN	MSigDB Cancer Gene Co-expression Modules	1.0	null
hsa-miR-4421	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35429
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101534
Microtubule-associated protein 6	InterPro Predicted Protein Domain Annotations	1.0	null
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924623
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03603
Replication fork protection complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.052
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903222
abnormal synaptic vesicle number	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11089
congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.139317
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SKUT1	DepMap CRISPR Gene Dependency	1.0	5.50148
PMC10568675-JCMM-27-3157-s003.docx-70-RFX3_RFX3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
shotgun	GeneRIF Biological Term Annotations	1.0	null
gamma-tubulin large complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04822
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5261-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02863
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39451
anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
abnormal maternal nurturing	MPO Gene-Phenotype Associations	1.0	null
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8433
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053233
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76821
YKT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61958
NCIH2882	DepMap CRISPR Gene Dependency	1.0	2.40434
MAP4K4	NURSA Protein-Protein Interactions	1.0	0.121092
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4491	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Chronic Chagas' Disease	DisGeNET Gene-Disease Associations	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12551
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25906
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.05461
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2358
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08677
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic membrane-bounded vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10413
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11361
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73747
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.74028
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.84944
JHOM1	CCLE Cell Line Gene CNV Profiles	1.0	1.46442
Perturb_13907_KD_UBE3A_SRP124518	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.6145
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.401
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051366
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101546_2_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12430004-ugae028_Supplemental_File.pdf-35-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
Field CA3, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01858
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.054
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.86919
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.053171
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75464
Aqueous Humor Disorders	DisGeNET Gene-Disease Associations	1.0	null
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44948
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24772
Sleep-Disordered Breathing	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6214_KO_Hdac_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.45554
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935537
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51901
Diffuse gastric cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.34205
Anophthalmia And Pulmonary Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
SUGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46343
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42107
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867999
CBFbeta_Deficiency_GDS3577_557_mouse_Regulatory T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.08919
PMC8283158-mmc2.xlsx-TCF4_Glut-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36784
decreased aggression	MPO Gene-Phenotype Associations	1.0	null
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43588
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10127
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09629
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	1.64567
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47822
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831849
NCI-H1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34161
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rif1_KD_GDS4943_243_mouse_F1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
abnormal sleep behavior	MPO Gene-Phenotype Associations	1.0	null
Neurofibrillary tangle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30952
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS852T	DepMap CRISPR Gene Dependency	1.0	8.85339
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF705B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89438
embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104009
PMC8208823-mmc2.xlsx-CDX2-dataset-feature_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
RARB	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15644
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4383005-ncomms7500-s4.xlsx-MinusSpecific_filteredGenes-Supplementary_Data_3_HES5-_vs_HES5_expression_intensity_ratios_during_NSC_progression_HES5	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of FCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00063
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86281
hyperactivity	MPO Gene-Phenotype Associations	1.0	null
Secondary motor area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05845
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80604
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.30574
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37014
non-membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221004_3_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92393
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM1S	DepMap CRISPR Gene Dependency	1.0	2.90151
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OQ-01A-32R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.849005
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48148
social withdrawal	MGI Mouse Phenotype Associations 2023	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
19168792-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25992
organelle organization	GO Biological Process Annotations 2015	1.0	null
DDX56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33027
NANOG-21062744-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86864
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	131.963
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Apnea	DisGeNET Gene-Phenotype Associations	1.0	null
MHHES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69384
microtubule cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061149
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.4518
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.947809
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.341
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17468
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04604
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S5-Supplemental_Table_S5_Genes_commonly_downregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
transport	GeneRIF Biological Term Annotations	1.0	null
NOLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07049
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47134
JEKO1	CCLE Cell Line Gene CNV Profiles	1.0	1.59679
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
perinuclear region of cytoplasm	GO Cellular Component Annotations 2015	1.0	null
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30554
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43728
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
protein complex binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_13750_KO_Bcl3_SRP179718	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.5284
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913106
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
lysosome localization	GO Biological Process Annotations 2015	1.0	null
GSE178255_3_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12494973-41467_2025_63880_MOESM1_ESM.pdf-168-KLF4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
maintain	GeneRIF Biological Term Annotations	1.0	null
Perturb_7124_KO_Prkcd/Prkce_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.025
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31252
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CALM1	Hub Proteins Protein-Protein Interactions	1.0	null
Perturb_2217_OE_H3f3a_SRP289821	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.22361
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062624
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04265
Perturb_13457_OE_Smn1_SRP366489	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.70379
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.5024
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939676
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61893
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
BL3118 (PPP4R2)	NURSA Protein Complexes	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Hyperkinesia	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00849
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02526
Tcf1_KO_GDS1473_307_mouse_Pancreatic islets	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
protein s deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.382223
ELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92723
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CNOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12156
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47488
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934047
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56281
CHLA90	DepMap CRISPR Gene Dependency	1.0	6.96824
Autosomal dominant nonsyndromic deafness 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07324
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.898727
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10932
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.079
SET2	DepMap CRISPR Gene Dependency	1.0	3.04169
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78564
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNCA	Hub Proteins Protein-Protein Interactions	1.0	null
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03936
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.576
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15474998-tableS1c	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
cell part morphogenesis	GO Biological Process Annotations 2015	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
Mesothelioma_MESO_TCGA-MQ-A6BR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
PMC11495544-JPN-240026-at-2.pdf-122-ARNT2_ARNT2	Rummagene Transcription Factor Associations 2026	1.0	null
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35797
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76667
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.608
layer 3 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51327
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
submandibular gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.509813
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28251
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25655
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
FANCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61137
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03284
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03995
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01934
TRIM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45803
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
calmodulin	GeneRIF Biological Term Annotations	1.0	null
19605494-TableS3	GeneSigDB Published Gene Signatures	1.0	null
ROCK_INHIBITION_GDS3944_462_mouse_Forebrain astrocytes - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.161
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_48h_2-down-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE153189_1_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Schizophrenia	DisGeNET Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.70265
ELL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46442
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056788
19185848-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Immune Thrombocytopenic Purpura	DisGeNET Gene-Disease Associations	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RH-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
16611997-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.20097
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFX_KO_GDS2718_151_mouse_hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.960818
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899175
NCIH1573	DepMap CRISPR Gene Dependency	1.0	5.56533
establishment of localization	GO Biological Process Annotations 2015	1.0	null
H3K27me3_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RASSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48746
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35466
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
MXRA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44446
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64396
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_splenic B cell_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31432
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE148514_0_v_1_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059183
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71114
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.930269
SNU-449	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Myelin membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.821
Supramolecular fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
abnormal aggression-related behavior	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-214	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00625
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66556
NB1	DepMap CRISPR Gene Dependency	1.0	5.07453
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46335
Asthma	DisGeNET Gene-Disease Associations	1.0	null
Peptic ulcer disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08406
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03685
GSE42805,GSE42811_1_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pulmonary microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501574
NH6	CCLE Cell Line Gene Expression Profiles	1.0	1.45133
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal synaptic vesicle morphology	MPO Gene-Phenotype Associations	1.0	null
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36784
GSE214823,GSE214824_4_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54411
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53637
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ST6GALNAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05547
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902698
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902605
CNOT3-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27923
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887896
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103623
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35332
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4711-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077247
m1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37649
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.09801
Perturb_15223_KD_FOXC1_SRP276213	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.33926
HSC-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4888-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81913
Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	2.37047
microtubule associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.352522
telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159302
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_6519_KD_S100A4_SRP105051	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.84478
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994599
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37808
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43585
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13644
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08625
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8168563-supp_gad.348295.121_Supplemental_Table_S2.xlsx-GSEA_ASCL1_ChIP_Targets-Unnamed_1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
U343	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.06886
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ENSG_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.432
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060494
PMC11867963-Table1.xlsx-Sheet1-BATF2_BATF2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1284	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
BL4214 (THRAP3)	NURSA Protein Complexes	1.0	null
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10096
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83744
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0917
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74292
EIF2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74606
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93513
SYK_druginhibition_284_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.5913
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36607
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924623
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89018_1_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4786-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54361
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
XBP1_OE_GDS5065_273_mouse_F424a adipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
REST_01_337	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.8281
Perturb_13295_KD_Klf5_SRP307776	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.57611
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23646
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-Overlap-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AKT1_Activation - 2 week induction_GDS2308_717_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EGFR_drugactivation_20_GDS2146	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.82469
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
lysosome localization	GO Biological Process Annotations 2023	1.0	null
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.236
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87251
CHK1_KD_GSE54267_672_human_U2OS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
chr11_75676115_AC_A_b38	GTEx eQTL 2025	1.0	1.43843
motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.275089
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74029
BL511 (PAK4)	NURSA Protein Complexes	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
18535662-TableS2d	GeneSigDB Published Gene Signatures	1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal sleep pattern	MPO Gene-Phenotype Associations	1.0	null
ES2	CCLE Cell Line Gene CNV Profiles	1.0	1.51251
Perturb_14391_KD_PAX8_SRP276625	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
KYSE-410	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0291
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
prefrontal	GeneRIF Biological Term Annotations	1.0	null
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9685
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.994231
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17851
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902189
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04143
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39428
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	1.3592
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.194232
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SKNAS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96702
E2F6	ENCODE Transcription Factor Targets	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81456
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	2.19474
FLI1	ChEA Transcription Factor Targets	1.0	null
NRL_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03263
8-MG-BA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.14719
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17511
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48824
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4405
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30038
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11335
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
PMC7069124__F4	PFOCR Pathway Figure Associations 2023	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.4905
cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.208579
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the coagulation cascade	GWASdb SNP-Phenotype Associations	1.0	0.232215
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15225_KD_lncRNALFAR1_SRP101771	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16183
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04059
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04653
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06544
Perturb_13190_KO_Wnt5a_SRP346437	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.44855
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19231
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal locomotor activation	MPO Gene-Phenotype Associations	1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5771
SMG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20957
Perturb_16427_KD_Atf3_SRP327850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.72505
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64007
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15589
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584422
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890017
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19219
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI-8402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476979
GSE225656_2_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150215_1_v_0_etl4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2907
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.306
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.92119
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94598
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61866
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CAMA-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25523
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46878
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05677
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Methionine	CTD Gene-Chemical Interactions	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.95914
Perturb_9447_KD_ESR2_SRP275562	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.81908
Transcription factor TFIIF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78868
Sleeplessness	DisGeNET Gene-Phenotype Associations	1.0	null
GSE137702_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90931
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.886057
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NB14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45894
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39633
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26711
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Otosclerosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24445
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0307
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.772246
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Golgi-associated vesicle	GO Cellular Component Annotations 2025	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028534
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.832154
macroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466111
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.027032
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27728
PMC10025425-mmc3.xlsx-ADNP_WH-gene_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.49252
tubulin binding	GO Molecular Function Annotations 2023	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0171
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24095
EGR1	ChEA Transcription Factor Targets	1.0	null
Axolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33909
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00901
SUZ12	ChEA Transcription Factor Targets	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10284
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lysosomes	GeneRIF Biological Term Annotations	1.0	null
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
polymeric cytoskeletal fiber	GO Cellular Component Annotations 2025	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
ZBTB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59567
SLC39A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71676
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6106
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.897256
Uveitis	DisGeNET Gene-Disease Associations	1.0	null
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24835
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.86656
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65308
cell projection morphogenesis	GO Biological Process Annotations 2015	1.0	null
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.24458
PMC4395454__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE137653_2_v_3_siglecf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07935
abnormal social investigation	MPO Gene-Phenotype Associations	1.0	null
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91695
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18731
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.972141
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24712
oculomotor nucleus, Edinger-Westphal subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23025
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085432
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4146
decreased prepulse inhibition	MGI Mouse Phenotype Associations 2023	1.0	null
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.854064
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967924
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863881
hsa-miR-4685-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.663368
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.07325
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49639
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37567
Perturb_13072_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.16101
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89027
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09169
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cortex	GeneRIF Biological Term Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37805
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74311
heart valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.11064
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.4664
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39169
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878046
BL8669 (MLLT6)	NURSA Protein Complexes	1.0	null
Sleep Apnea	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181019
MHHNB11	CCLE Cell Line Gene Expression Profiles	1.0	1.8883
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.582196
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.972024
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1363_KO_NAT10_SRP367833	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.70939
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	1.36119
EP300	ENCODE Transcription Factor Targets	1.0	null
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27706
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulation of microtubule cytoskeleton organization	GO Biological Process Annotations 2025	1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_5524_KO_Trpm7_SRP409200	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07811
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03153
GSE76425_1_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fetal alcohol syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07888
adapting	GeneRIF Biological Term Annotations	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of neurogenesis	GO Biological Process Annotations 2025	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20529
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10305
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51816
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53271
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23136
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.08538
Myeloid Leukemia	DisGeNET Gene-Disease Associations	1.0	null
parolfactory gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.932545
Hyperphosphatasia with impaired intellectual development syndrome 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24054
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
neuron projection morphogenesis	GO Biological Process Annotations 2025	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5106
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01381
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80272
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Golgi-associated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01275
Perturb_9652_KD_COPS2_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.26907
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.915947
GSE184087_0_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45441
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.87963
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02578
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973769
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.057
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.142
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE254517_2_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.0043
MBTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4892
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_394_KO_FOXM1_SRP272209	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.66178
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mucopolysaccharidosis III	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
Eye Abnormalities	CTD Gene-Disease Associations	1.0	1.07093
ebstein anomaly	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08327
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51177
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868953
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950093
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857344
CGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18736
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3126-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872051
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61086
FBXO48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55953
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03294
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12299
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70693
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06929
GSE239457_1_v_0_rasa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.01437
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29745
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01331
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39184
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
granule cell layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98307
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.443547
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.979286
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS CoV_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58445
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20673
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0399
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.278
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.69159
regulation of microtubule cytoskeleton organization	GO Biological Process Annotations 2023	1.0	null
microtubules	GeneRIF Biological Term Annotations	1.0	null
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29745
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11390959-41598_2024_70075_MOESM3_ESM.xlsx-520_DMD_common_down_gene_list-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
Difficulty Sleeping	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_10615_OE|KO_Stk4|Lgals3_SRP121622	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.0818
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43227
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.34711
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23995
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.882158
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.077511
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121148
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1664
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE208435_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06721
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.377031
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059023
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03146
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31807
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23547
hsa-miR-548e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC3590650-bjc2012518x7.xls-Sheet1-Supplementary_Table_S3_list_of_predicted_target_genes_for_miR29c_present_in_both_PITA_and_Targetscan_predictions_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-29c	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ACADS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72714
GSE139239_1_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5387
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75I-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223906
Inflammation	CTD Gene-Disease Associations	1.0	1.58561
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70557
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.81579
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90703
HS852T	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
PMC5316868__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953345
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63264
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64344
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15459
SNU761	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59424
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63673
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054756
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61956
PMC12686523-41421_2025_842_MOESM6_ESM.xlsx-Table_S5-Supplementary_Table_S5_-_Target_genes_of_FOXG1_in_GBM_FOXG1	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1567
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.22758
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
rabies	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.544705
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.67499
NCIH1963	CCLE Cell Line Gene Expression Profiles	1.0	2.20667
brucellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.430393
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31379
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.191
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dendrite morphogenesis	GO Biological Process Annotations 2015	1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913172
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934802
hsa-miR-4474-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
PFKL_OE_GDS1079_201_mouse_myoblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0291
SLC25A32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72709
SAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tubulin binding	GO Molecular Function Annotations 2025	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.20833
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.900056
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37041
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hela	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00856
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.989758
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02601
Metabolic Syndrome X	DisGeNET Gene-Disease Associations	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Type I spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61743
Acute Myeloid Leukemia_LAML_TCGA-AB-2830-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12062214-41467_2025_59646_MOESM5_ESM.xlsx-HMGA2_activated_repressed-Gene_symbol_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00427
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_CNOT3_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AW-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70345
molecular	GeneRIF Biological Term Annotations	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18076
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70666
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Regurgitation	DisGeNET Gene-Phenotype Associations	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.32535
social withdrawal	MPO Gene-Phenotype Associations	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985088
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069297
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of microtubule-based process	GO Biological Process Annotations 2025	1.0	null
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48919
Perturb_13077_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.62186
Atrophy	CTD Gene-Disease Associations	1.0	1.48761
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057325
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.598067
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_61_KO_Usp16_SRP271781	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.59381
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84767
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12915
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BL7007 (ZNF574)	NURSA Protein Complexes	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.973876
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14098
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05654
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13203
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13456_OE_Smn1_SRP366489	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.2063
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.838215
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1930	CCLE Cell Line Gene Expression Profiles	1.0	3.40804
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09739
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Supramolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.37818
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28258
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65711
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.41721
Pitcher	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910852
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	127.6
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935537
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935611
Chronic traumatic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
Hippocampal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3019
GSE93156_1_v_0_idelalisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41066
HMGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22656
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-A549_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_A549_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16685
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20692
thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.428516
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927717
RARG	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853511
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_H3K27me3-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Muscle Weakness	DisGeNET Gene-Phenotype Associations	1.0	null
GSE158834_1_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-412	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06869
Perturb_16496_KO_Ptpn2_SRP159185	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.92462
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.682275
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134191_6_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19285
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05778
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03999
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08406
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.07549
positive regulation of cell projection organization	GO Biological Process Annotations 2023	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.966415
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.3314
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830809
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16483
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9239
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the common coagulation pathway	GWASdb SNP-Phenotype Associations	1.0	0.58452
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Anterior commissure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03203
SF295	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39091
BL3250 (DDX31)	NURSA Protein Complexes	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13977
ChIP_KLF4_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-4259	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04402
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7941
differentially	GeneRIF Biological Term Annotations	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904604
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69925
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38044
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.54208
tubulin binding	GO Molecular Function Annotations 2015	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25655
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTDSPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74128
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31807
Edema	CTD Gene-Disease Associations	1.0	1.21108
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31187
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cis-Golgi network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1411
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912122
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849155
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48909
PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2047
intermediate stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51643
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48633
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Violence	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_12859_KO_Lrp1_SRP154938	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.49172
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZWILCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61297
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19847
protein binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844626
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20968
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2616
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38818
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.996444
GSE210225_0_v_1_inosine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Colitis	DisGeNET Gene-Disease Associations	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00063
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SKMEL30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38793
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC366	CCLE Cell Line Gene CNV Profiles	1.0	1.35307
mitotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.385822
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.17969
abnormal behavioral response to amphetamine	MGI Mouse Phenotype Associations 2023	1.0	null
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
abnormal pup retrieval	MGI Mouse Phenotype Associations 2023	1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dermatofibroma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96082
Dendritic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.938
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46144
Primary progressive aphasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.260538
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882407
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988193
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08697
Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.024429
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221989
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01189
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.879123
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Field CA3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03603
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14245
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60676
hsa-miR-29b	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.357802
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brake	GeneRIF Biological Term Annotations	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33086
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
TES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16584
ESCRT III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.105
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.967396
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847775
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16781_KD_Msi2_SRP061564	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.45477
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82079
GSE158834_1_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC37A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37905
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0652
GSE86507,GSE86509_3_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11368
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875827
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
PREB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51965
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4056
GSE213219_2_v_3_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF793	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27345
PMC6438015-13148_2019_651_MOESM7_ESM.xlsx-Sheet1-Table_S2_Genes_exhibiting_both_significantly_increased_promoter_methylation_and_significantly_lowered_expression_in_CRISPR_TET2-KO_cells_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Complicated Intra-Abdominal Infection	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44695
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TE-15	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.002
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39169
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47408
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22671
Perturb_3140_KD_HSALNG0104472_SRP371179	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.00815
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.141
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935537
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15676
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00271
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12459
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829118
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971778
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196699_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
RHPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15267
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60184
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20545
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.14541
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S12-Table_S12_MR_resluts_of_brain_pQTL_and_any_ischemic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Somnolence	DisGeNET Gene-Phenotype Associations	1.0	null
GLIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0507
IQGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46925
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polymeric cytoskeletal fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Depression	DisGeNET Gene-Disease Associations	1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.27507
Iga Glomerulonephritis	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paresis	DisGeNET Gene-Phenotype Associations	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.941785
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
GSE143643,GSE143644_2_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fetal alcohol spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
NMC-G1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59255
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
Gastric ulcer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Microtubule end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.175
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66941
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.972323
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.006
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884359
hsa-miR-29a	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
HEC251	DepMap CRISPR Gene Dependency	1.0	3.31396
microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7888
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComUp-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SEC61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02483
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89018_11_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40872
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901029
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.850204
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4552
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21558
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
hsa-miR-2113	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163938
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863652
15273739-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08406
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03146
BL3041 (ERBB4)	NURSA Protein Complexes	1.0	null
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4965
ING3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28287
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	216.948
cytoskeleton	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54839
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Axon	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
SLR26	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49045
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25437
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.77131
membrane-bounded vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t64-ovaries_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.08741
MAFK	ENCODE Transcription Factor Targets	1.0	null
Submandibular gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
BL5105 (BRF1)	NURSA Protein Complexes	1.0	null
Subcortical band heterotopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1903
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07896
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876565
Myelin sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
Breast Cancer_Mammary Gland Tissue_GSE1378	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.65229
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41258
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5356
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43128
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4474-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE209928_0_v_1_kmt2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32133
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Field CA3, stratum lucidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03203
USF1	ENCODE Transcription Factor Targets	1.0	null
METTL21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2918
STON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40453
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.012
Alcohol Use Disorder	DisGeNET Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ductal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08486
OE19	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
Endometriosis_Endometrium_GSE7305	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.82729
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867298
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938077
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pontine nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
TRIM28	ChEA Transcription Factor Targets	1.0	null
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_15293_OE_Fos_SRP304877	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.4696
GSE200352_1_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34787
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36898
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.22858
PMC8628126__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_3027_KO_Hif1a_ERP124464	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.51097
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876219
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07857
NB1	CCLE Cell Line Gene Expression Profiles	1.0	1.64664
PC3	DepMap CRISPR Gene Dependency	1.0	2.65541
Diphtheria	DisGeNET Gene-Disease Associations	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood platelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247079
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10811
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.948904
GSE199538,GSE199539_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.13342
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATXN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03549
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25821
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
Orbital area, medial part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37649
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41824
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.90826
macromolecular complex binding	GO Molecular Function Annotations 2015	1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.3209
BL8109 (RAD54L2)	NURSA Protein Complexes	1.0	null
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
METTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28648
microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.131934
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.25734
neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
Perturb_2889_KO_Mcrip2_SRP302058	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7833
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857759
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.06232
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-3907	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
EWS502	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.36952
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
masseter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.458373
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41344
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4763-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hsa-miR-205	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Poliomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18059
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4696	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
NMB	DepMap CRISPR Gene Dependency	1.0	6.67553
cell morphogenesis involved in neuron differentiation	GO Biological Process Annotations 2023	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Dentate gyrus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76728
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Postgastrectomy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08929
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19496
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.17834
PKN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52459
CBC632 (AKAP13)	NURSA Protein Complexes	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.26194
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06224
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23256
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89455
Perturb_12337_KD_TFEB_SRP226507	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.93025
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.72405
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10115
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05917
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0059
A-VN-1203-2004(H5N1)_Day7-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69972
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-AF_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE136238_1_v_2_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12296_KD_RORC_SRP066204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.6739
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64262
Kidney Chromophobe_KICH_TCGA-KN-8437-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3747
MIS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22488
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90682
astroglial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241746
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8064
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308612
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905557
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSS008	DepMap CRISPR Gene Dependency	1.0	4.32462
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21776
Perturb_1486_KO_Rbx1_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.48229
Cardiac Arrhythmia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40905
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5430_OE_ATF3_SRP308440	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.88416
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46332
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062799
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843879
MAGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63785
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peripheral nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
calmodulin binding	GO Molecular Function Annotations 2015	1.0	null
GSE100102_0_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
microtubule cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
TUBA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4928
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S14-Table_S14_MR_resluts_of_brain_pQTL_and_cardioembolic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84334
heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.318999
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
Atrial Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HMGA2_KO_GDS5048_26_mouse_embryonic lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parkinson Disease	DisGeNET Gene-Disease Associations	1.0	null
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	1.59854
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22801
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.012
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Xia-Gibbs Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05796
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25161
SLTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10093
polymeric cytoskeletal fiber	GO Cellular Component Annotations 2023	1.0	null
carotid artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.36187
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41096
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26406
Transient Ischemic Attack	DisGeNET Gene-Disease Associations	1.0	null
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06953
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63591
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ECC4	DepMap CRISPR Gene Dependency	1.0	2.84108
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15218
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7735
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.763286
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01543
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919365
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04258
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15776
KMS11	DepMap CRISPR Gene Dependency	1.0	4.22949
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7050-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37139
19621087-Table1e	GeneSigDB Published Gene Signatures	1.0	null
dendrite morphogenesis	GO Biological Process Annotations 2023	1.0	null
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58608
PECAPJ41CLONED2	CCLE Cell Line Gene CNV Profiles	1.0	1.42631
MAZ	ENCODE Transcription Factor Targets	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.81003
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2507
SBNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978554
positive regulation of axonogenesis	GO Biological Process Annotations 2023	1.0	null
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.937899
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05707
Proteinuria	CTD Gene-Disease Associations	1.0	1.08161
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.71583
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068353
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
carotid stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.436026
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05381
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5883-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
18081427-TableS7	GeneSigDB Published Gene Signatures	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00132
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08395
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971103
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68159
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
non-hodgkin lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187069
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38838
Perturb_7255_KD_PARP1_SRP410217	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.699
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05665
Growth cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.43
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	1.58798
circling	MPO Gene-Phenotype Associations	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5859
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CMG complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.15324
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.360395
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08615
Perturb_15070_KD_Twist1_SRP150075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.8104
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.786
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0486
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98831
abnormal maternal behavior	MPO Gene-Phenotype Associations	1.0	null
GSE254517_1_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oligodendrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.45374
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59255
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055619
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832265
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1316
PMC6811834-sby183_suppl_supplementary_data_set_1.xls-ZNF804A_DEX_FDR_0_01-Gene_Symbol_ZNF804A	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE194396,GSE194429_2_v_3_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60688
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10278
MAP6/FAM154	InterPro Predicted Protein Domain Annotations	1.0	null
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.931014
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.32828
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.13724
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.869102
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1428
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.685959
GSE150215_1_v_2_etl4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05355
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.802205
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69395
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210225_0_v_1_uba6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15082_KD_Ehmt1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.5594
PMC7304190-13229_2020_355_MOESM18_ESM.xlsx-Supplemental_Table_5-hNSCs_SATB2_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MM160113	DepMap CRISPR Gene Dependency	1.0	5.673
trafficking	GeneRIF Biological Term Annotations	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05392
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0635
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84407
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.862299
H2AZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3694
THAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65684
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07524
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.958665
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10233
Vascular type Ehlers-Danlos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16163
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2803-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.66914
circling	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933315
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW982	DepMap CRISPR Gene Dependency	1.0	3.02394
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16674
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11836325-41467_2025_56634_MOESM8_ESM.xlsx-gene_table_NGS5844-Supplementary_Data_6_Gene_targets_lost_in_resistant_cells_upon_FOSL1_knockdown_and_their_corresponding_hallmark_pathway_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889032
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8791933-41598_2022_4817_MOESM4_ESM.xlsx-PAX7_down-Unnamed_1_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60878
FOXJ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45178
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920024
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08439
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-01A-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927398
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09008
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945975
GLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35659
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.897183
LNZ308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39997
Perturb_14002_KD_Dek_SRP376103	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.75442
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_5_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33559
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
microtubule-based process	GO Biological Process Annotations 2015	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866701
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
Deficiency Of Testosterone Biosynthesis	DisGeNET Gene-Disease Associations	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904618
hsa-miR-376c	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
tmem106bmap6	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00574
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
acting	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperphosphatasia with impaired intellectual development syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29122
RPLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24216
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183189
FUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86563
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_7_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40136
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07129
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24049
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55319
TE14	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71779
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.46113
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11179
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.841125
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958644
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982676
rat-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.524377
Growth Disorders	CTD Gene-Disease Associations	1.0	1.24433
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10637
hsa-miR-4753-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.107604
Carpal tunnel syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15126
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SEC61G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31311
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3742
hsa-miR-520g	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74693
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94819
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-2.30949
MEIOSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55926
PMC8260656-41467_2021_24380_MOESM4_ESM.xlsx-ERG_EZH2-ATTENUATED_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
POGLUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65165
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07086
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07307
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05085
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0636
Choline	CTD Gene-Chemical Interactions	1.0	null
ADNP_Deficiency - NULL MUTATION_GDS2540_692_mouse_E9 embryos - Homozygous mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.341
Congestive Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
induced hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64685
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04193
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.641715
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11041
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07026
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KSR1_knockout_126_GSE28228	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.17007
Lung squamous cell carcinoma_LUSC_TCGA-33-4582-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74179
PMC7771094-12920_2020_832_MOESM5_ESM.txt--ATF2_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.052
GSE157262,GSE157268_3_v_0_ythdc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.29178
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9345
hESC_Derived_CD184+_Endoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.01123
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-4.09841
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.991968
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pituitary Adenoma	DisGeNET Gene-Disease Associations	1.0	null
ONDA8	DepMap CRISPR Gene Dependency	1.0	2.05461
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28957
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68392
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
km3	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905551
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2821
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76828
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952253
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84798
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNUC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46588
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.369373
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950087
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2771
Perturb_12040_OE_S100a9_SRP313839	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247399
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
OCIM1	CCLE Cell Line Gene CNV Profiles	1.0	1.88278
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02791
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.830704
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LN382	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07753
PMC7069124__F4	PFOCR Pathway Figure Associations 2024	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04129
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.553491
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989186
SNU216	DepMap CRISPR Gene Dependency	1.0	2.53648
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
microtubule binding	GO Molecular Function Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5846
INTS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47597
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9449_OE_ALS/FUS_SRP297132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.30452
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Malaria	DisGeNET Gene-Disease Associations	1.0	null
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14641
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20974
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00876
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.203361
Perturb_7123_KO_Prkcd_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.70385
Rat-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08688
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERBB2_druginhibition_8_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.41008
DIFI	DepMap CRISPR Gene Dependency	1.0	2.16029
presumably	GeneRIF Biological Term Annotations	1.0	null
Progressive supranuclear palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
PMC8283158-mmc2.xlsx-TCF4_NPC-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Neurosphere_Cultured_Cells_Cortex_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.15729
superficial stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83848
GSE212312_1_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05162
PMC3470785-NIHMS377161-supplement-12.pdf-601-DACH1_DACH1	Rummagene Transcription Factor Associations 2026	1.0	null
leptospirosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.538893
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.89992
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4395454__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.191
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.742281
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09829
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08278
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18674
u937	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	1.0	1.63357
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08386
E2F1_KD_GDS4094_446_mouse_Mammary tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92252
Perturb_15777_KO_Nmnat1_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.89281
Perturb_3173_KD_LEF1_SRP277903	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.35834
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052145
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064612
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845043
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CLCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20837
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90273
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954416
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889032
dendrite morphogenesis	GO Biological Process Annotations 2025	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16827_KO_MLL4_SRP058264	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.7263
KLF4-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_15507_KD_MYC_SRP279303	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.3423
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058537
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3498
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ICAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32135
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03931
METTL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93409
PMC7899452-media-4.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78291
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964349
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.565923
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25549
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9577795__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.9995
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
GSE110178_2_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271256
PMC10769395-media-2.xlsx-S2D_EF_Repressed_genes-Ebegboni_et_al_Supplemental_Table_S2D_Increased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11973_KO_Soat1_SRP235547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.84855
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20701
impaired synaptic plasticity	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Dumping syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80028
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.59533
SCC25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45368
Somatodendritic compartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04584
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840548
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864917
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72552
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-1972	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
PMC8168563-supp_gad.348295.121_Supplemental_Table_S2.xlsx-GSEA_ASCL1_ChIP_Targets-ASCL1_ChIP_Targets_Conserved_in_mose_SCLC_and_human_SCLC_Models_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
YD38	DepMap CRISPR Gene Dependency	1.0	2.40314
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.2041
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900562
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09204
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064177
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.46341
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08192
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.64323
NAMALWA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46298
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921701
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02937
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49506
neonatal lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
BL5519 (PCNT)	NURSA Protein Complexes	1.0	null
TUBB	Hub Proteins Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Axon cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.453
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.097838
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.04904
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824014
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78559
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055464
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076453
H1_BMP4_Derived_Trophoblast_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.69641
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
impaired synaptic plasticity	MPO Gene-Phenotype Associations	1.0	null
Ca9-22 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
FBRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86966
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64305
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.831881
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924623
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50154
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78339
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7064
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91866
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCLC21H	CCLE Cell Line Gene Expression Profiles	1.0	2.05264
KPNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41441
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890694
intracellular non-membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
NB4	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.0155
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18291
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06398
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85551
NCIH1573	CCLE Cell Line Gene CNV Profiles	1.0	1.58689
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909227
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0394
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31173
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15931
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10285
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.236
NANOG-18700969-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49671
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48252
GSE101112_0_v_2_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAF1	Pathway Commons Protein-Protein Interactions	1.0	null
caco2	HPA Cell Line Gene Expression Profiles	1.0	1.26286
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.4423
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15375
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09631
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05681
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11002
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25304
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.33233
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907044
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Supramolecular polymer	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
WDR44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66119
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05725
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881098
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46887
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23547
hsa-miR-4800-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28773
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4N-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03774
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22426
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65595
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42721
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26284
GSE214823,GSE214824_4_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930831
GSE214823,GSE214824_3_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Trichohepatoenteric Syndrome	DisGeNET Gene-Disease Associations	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.778212
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838544
Lung squamous cell carcinoma_LUSC_TCGA-43-A475-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955916
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.65136
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22757
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02097
cytoskeletal protein binding	GO Molecular Function Annotations 2015	1.0	null
GSE179880_2_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.928662
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909397
synapse part	LOCATE Curated Protein Localization Annotations	1.0	null
axon	GO Cellular Component Annotations 2023	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825924
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03511
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12389
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832537
organisms	GeneRIF Biological Term Annotations	1.0	null
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06515
19235837-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20176
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE153124_4_v_0_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8299217-mmc3.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956489
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.984671
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13069_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.39584
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.175938
Wernicke-Korsakoff syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
neuron projection morphogenesis	GO Biological Process Annotations 2015	1.0	null
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09739
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60627
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
microtubule binding	GO Molecular Function Annotations 2025	1.0	null
hsa-miR-3148	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67991
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22181
cytoplasmic vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09739
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87696
increased exploration in new environment	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859229
BICR22	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69729
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10087102-LSA-2023-02054_TableS5.xlsx-Sheet_1_-_Supplementary_Table_6-Supplementary_Table_6_PITA_filtered_output_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13080_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.59769
H2BC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79144
biological_process	GO Biological Process Annotations 2015	1.0	null
16651409-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Cancer Pain	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_11828_KO_Ptpdc1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.03747
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897191
YAPC	CCLE Cell Line Gene CNV Profiles	1.0	1.503
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.292257
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21466
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15280_OE_Foxa1_SRP189075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.69382
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10494
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
HCE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peripheral nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
REST_01_211	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58692
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86128
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
exposed	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054073
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.012
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32403
abnormal emotion/affect behavior	MPO Gene-Phenotype Associations	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10966
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864042
NZM42	DepMap CRISPR Gene Dependency	1.0	3.3626
Snoring	DisGeNET Gene-Phenotype Associations	1.0	null
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65923
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC2785767-1741-7007-7-79-S2.DOC-0-Day_5_IR_vs_OUT_4_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06619
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71423
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral ventricle	HPA Tissue Protein Expression Profiles	1.0	0.953245
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.530693
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1545_KO_Rbx1_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.93126
Habenular trigone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
abnormality of coagulation	GWASdb SNP-Phenotype Associations	1.0	0.211744
MV411	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08865
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.728
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33087
BL269 (MCM8)	NURSA Protein Complexes	1.0	null
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18669
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF2	ChEA Transcription Factor Targets	1.0	null
DYNLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48347
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51708
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23035
BL2777 (NF2)	NURSA Protein Complexes	1.0	null
Epileptic Syndromes	DisGeNET Gene-Disease Associations	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12823551-mmc2.xlsx-S1B-down_genes_Rbl2_KD_neuro-Unnamed_0_AR	Rummagene Transcription Factor Associations 2026	1.0	null
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01625
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055371
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25648
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.610778
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85145
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34079
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071414
Schizophrenia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
PMC7237311__F5	PFOCR Pathway Figure Associations 2024	1.0	null
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48626
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01625
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.553491
MBLAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73348
SNU387	CCLE Cell Line Gene CNV Profiles	1.0	1.38804
myotonic dystrophy type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298371
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14884
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2052	Achilles Cell Line Gene Essentiality Profiles	1.0	1.96792
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24681
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decrease	GeneRIF Biological Term Annotations	1.0	null
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13242
PMC5316868__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Impaired Glucose Tolerance	DisGeNET Gene-Phenotype Associations	1.0	null
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
tcf12_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.07907
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52651
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01992
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12777
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.26188
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09753
SKNO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01262
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39441
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.944146
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIMS2	NURSA Protein-Protein Interactions	1.0	0.046806
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
Mitotic arrest phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
YME1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25816
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4686761-ncomms10068-s3.xlsx-S2E-MSC_up_specific-Supplementary_Data_2E_-_expression_of_up-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05009
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dentate gyrus, granule cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9973
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2289
PMC6361956__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4303	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60242
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03124
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-510	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31717
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
long insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.898632
Ammon's horn	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0387
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7628
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24325
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_3_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89563
vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
Perturb_14114_KD_ATF7IP_SRP156289	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.68489
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847719
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901536
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.927997
tet1_21295276_mesc_v6.5_lof_mouse_gpl6887_gse26900	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.19447
Neuron projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
Infertility, Male	CTD Gene-Disease Associations	1.0	1.15492
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58356
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
BAIAP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56299
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular localization	GO Biological Process Annotations 2015	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08927
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12078
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_16512_KD_PAX9_SRP300302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
organelle localization	GO Biological Process Annotations 2015	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastric Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hyperkinesis	CTD Gene-Disease Associations	1.0	2.88009
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37021
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064838
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.967154
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0912
hsa-miR-4530	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19369
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28697
NANOG	ChEA Transcription Factor Targets	1.0	null
H3K27me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34099
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56581
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14208
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0303
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.855351
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.2393
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882993
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879425
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.342233
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25641
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16817
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Overweight And Obesity	DisGeNET Gene-Disease Associations	1.0	null
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11042
alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.268687
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5641-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.10014
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4680-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1112
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	1.0	1.51279
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00713
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880356
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_CAMTA1_vs_subEV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KRBOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03357
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00546
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40647
Endothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.766539
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27377
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MED17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17638
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924623
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959933
G402	DepMap CRISPR Gene Dependency	1.0	2.70395
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Field CA3, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10278
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15384
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31432
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23547
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241746
suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.09328
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57786
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
transport	GO Biological Process Annotations 2015	1.0	null
FAM118B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32706
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93483
Field CA2, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44616
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH2171	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33382
Anxiety	DisGeNET Gene-Disease Associations	1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05358
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.51876
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.20722
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.963713
sensor	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0869
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945449
CBC2032 (ZMYND8)	NURSA Protein Complexes	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Obsessive-Compulsive Disorder	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3109
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.012
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dendritic tree	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
APPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82387
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6948
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.962585
all	GWASdb SNP-Phenotype Associations	1.0	0.028512
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
microtubule	GO Cellular Component Annotations 2015	1.0	null
GSE85995_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166308_1_v_0_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4224
Mental Depression	DisGeNET Gene-Disease Associations	1.0	null
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24325
abnormal social/conspecific interaction	MPO Gene-Phenotype Associations	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867829
ADCYAP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13635
BL5502 (HDAC6)	NURSA Protein Complexes	1.0	null
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23891
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
according	GeneRIF Biological Term Annotations	1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073513
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27139
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03999
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29004
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04204
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5714_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.5229
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188398
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11762
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16148
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23294
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BMPR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71505
GSE202434,GSE202438_3_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51534
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5387
GSE111035,GSE111040_8_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prelimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30438
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.341
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47195
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.02023
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4732-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2973
dendrite	GO Cellular Component Annotations 2025	1.0	null
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155031_5_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65711
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02791
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01241
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF384	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20175
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC5322732__F6	PFOCR Pathway Figure Associations 2024	1.0	null
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97165
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843113
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936727
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
akinesia	MPO Gene-Phenotype Associations	1.0	null
GSE151119_2_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25411
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2827
ESR1-22446102-UTERI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11028
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929188
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smarcc2_00000000_e12dot5_embryonic_cortex_lof_mouse_gpl6887_gse45629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.094753
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4697-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.29352
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.982186
H4K20me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4676-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
decreased aggression	MGI Mouse Phenotype Associations 2023	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827027
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13211
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.337
Nde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42377
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18799
GSE130676_0_v_1_suds3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-622	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Perturb_3903_KD_HNF4A_SRP123224	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.30197
APLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89445
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21147
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26731
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17233
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.964
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20993
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72037
regulation of cytoskeleton organization	GO Biological Process Annotations 2025	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-KLF6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.46727
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08406
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
19139136-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Perturb_10614_OE_Stk4_SRP121622	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.3555
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45901
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased anxiety-related response	MPO Gene-Phenotype Associations	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49789
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825924
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MYB	ChEA Transcription Factor Targets	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.295655
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38921
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060768
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.66271
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08625
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.38904
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11028
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850651
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93359
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal pup retrieval	MPO Gene-Phenotype Associations	1.0	null
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
submandibular gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18805
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945659
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30056
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DBTRG05MG	Achilles Cell Line Gene Essentiality Profiles	1.0	1.86852
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061181
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18011
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.778212
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.741517
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ARHGEF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01245
abnormal parental behavior	MPO Gene-Phenotype Associations	1.0	null
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65149
GSE114992,GSE114993_1_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22534
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7098486-mmc2.xlsx-Kgg_Quant_NGN2_AAVS_-_WCL-Unnamed_2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0059
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9328
Pyoderma	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936727
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.191
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50217
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_SUZ12-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_15708_KD_Ctcf_SRP173291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46125
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842012
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.5619
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell projection organization	GO Biological Process Annotations 2015	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.746689
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13043
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18694
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46656
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.21267
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EXOSC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27937
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S11-Table_S11_MR_resluts_of_brain_pQTL_and_any_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
thrombophilia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.134408
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20307
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18085
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9258
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03336
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48916
Lung adenocarcinoma_LUAD_TCGA-78-7161-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918184
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	1.24908
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872671
Dynactin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.251
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14495