association dataset threshold value standardized value primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.5814 JAK2_knockout_79_GSE26188 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.46918 male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.303919 primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.27313 H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4776-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 inner SZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16395 REST_PFSK-1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Olfactory tubercle, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21424 NCI-H2110 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD3 ChEA Transcription Factor Targets 1.0 null intermediate stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.474 Perturb_14224_KO_Tcf12_SRP392331 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.66679 intermediate stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3607 TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05536 no abnormal phenotype detected MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SMAD3-21741376-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.296631 ABC1 CCLE Cell Line Gene CNV Profiles 1.0 2.46225 HCE-4 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.933867 RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null protein modification by small protein conjugation GO Biological Process Annotations 2015 1.0 null outer SZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.90312 CLPP_KO_GSE40207_379_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null inner SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16407 Abducens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69667 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null PARP MotifMap Predicted Transcription Factor Targets 1.0 null cellular metabolic process GO Biological Process Annotations 2015 1.0 null VZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.858737 alar plate of p1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14823 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.831684 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null membrane GO Cellular Component Annotations 2015 1.0 null MAX_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.995355 H3K36me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38711 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.4425 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.865111 medial mammillary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.909566 ABC-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 ventrolateral prefrontal cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.887955 anteroventral periventricular preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00296 superficial stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35651 spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.19067 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.18472 H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.911943 CTBP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.526744 CHD7 ENCODE Transcription Factor Targets 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null rostral division of VL Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.82603 PHF8 ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.108 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07451 SUZ12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cortical amygdalar area, posterior part, lateral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28338 primary auditory cortex (core)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.34513 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46959 Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OV7 DepMap CRISPR Gene Dependency 1.0 3.2294 Medial amygdalar nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.67655 Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43018 lateral SC part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33661 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nucleus of the lateral olfactory tract, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.01693 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null NCI-H1781 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.40167 GATA3 ENCODE Transcription Factor Targets 1.0 null H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null r4 liminal central gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40286 periventricular stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41733 VZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14519 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06146 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.82844 H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TAF7 ENCODE Transcription Factor Targets 1.0 null amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.891843 H3K27me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null deep white layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84916 Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00881 hypothalamic amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84902 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.5858 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042766 hand TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.7335 REST_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null organelle part GO Cellular Component Annotations 2015 1.0 null medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.873247 Sleeplessness DisGeNET Gene-Phenotype Associations 1.0 null H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945753 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.829807 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null HCC70 CCLE Cell Line Gene CNV Profiles 1.0 1.68898 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08845 NCI-H196 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 terminal hypothalamus (rostral hypothalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.027 endopiriform nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21309 NCI-H441 COSMIC Cell Line Gene Mutation Profiles 1.0 null SHP77 CCLE Cell Line Gene Expression Profiles 1.0 1.475 SMAD4 ChEA Transcription Factor Targets 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.38074 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SNU1214 CCLE Cell Line Gene Expression Profiles -1.0 -1.48007 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 1.82736 SKLU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.65227 H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null organelle membrane GO Cellular Component Annotations 2015 1.0 null superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36452 polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.918555 protein modification by small protein conjugation or removal GO Biological Process Annotations 2015 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8257-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CORL88 CCLE Cell Line Gene Expression Profiles 1.0 1.62436 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.074391 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.65632 NCIH510 CCLE Cell Line Gene Expression Profiles 1.0 1.35321 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5752 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW900 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MEC1 DepMap CRISPR Gene Dependency 1.0 5.30698 CBX3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039714 intermediate stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15668 H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MDAMB436 DepMap CRISPR Gene Dependency 1.0 2.14159 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.04023 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962125 supraoptic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.60841 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03165 somatic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.397979 Olfactory tubercle, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30777 Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LCLC-103H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.970661 Perturb_13588_KD_Adamtsl2_SRP341310 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 NZM42 DepMap CRISPR Gene Dependency 1.0 2.16685 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26431 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null APLN_KO_GDS3228_601_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC2279 CCLE Cell Line Gene Expression Profiles -1.0 -2.4123 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein ubiquitination GO Biological Process Annotations 2015 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null VZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.847068 mantle zone of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39317 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.872134 KMS26 DepMap CRISPR Gene Dependency 1.0 2.32818 HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93565 colitis GWASdb SNP-Phenotype Associations 1.0 0.355555 Lung squamous cell carcinoma_LUSC_TCGA-56-8082-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16332 REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06459 cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null acute myocardial infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.596792 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.938005 REST_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055041 Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01822 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.14844 Orbital area, medial part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25748 posteroventral (inferior) parietal cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.928163 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null PMC3972651__F2 PFOCR Pathway Figure Associations 2023 1.0 null Basomedial amygdalar nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04198 PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GABPA_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053049 H3K27me3_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HA-E2F1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13256 OCI-AML5 COSMIC Cell Line Gene Mutation Profiles 1.0 null PACADD161 DepMap CRISPR Gene Dependency 1.0 3.71271 NCI-H1623 COSMIC Cell Line Gene Mutation Profiles 1.0 null layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33711 H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null NCIH1869 CCLE Cell Line Gene CNV Profiles 1.0 2.0097 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNB19 CCLE Cell Line Gene Expression Profiles -1.0 -3.18376 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null Medial amygdalar nucleus, posterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30057 H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null sperm part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.099299 ventral posterior lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.972488 H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33434 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35042 REST_Panc1_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAL-12T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.916622 MMAC DepMap CRISPR Gene Dependency 1.0 6.28138 NCIH1623 CCLE Cell Line Gene Expression Profiles -1.0 -1.73269 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09019 superficial stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4252 magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.938985 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65724 lateral spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44534 BV-173 COSMIC Cell Line Gene Mutation Profiles 1.0 null integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30439 CORL279 CCLE Cell Line Gene Expression Profiles 1.0 2.03104 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of metabolism GWASdb SNP-Disease Associations 1.0 0.103638 H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-576-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 H3K27me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07767 metal ion binding GO Molecular Function Annotations 2015 1.0 null Weight Loss CTD Gene-Disease Associations 1.0 1.08655 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.034173 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null coronary artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.309204 medial group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.90908 H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34196 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.21806 layer 3 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35589 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20P-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nucleus of the lateral olfactory tract, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72128 anterior pretectal nucleus, dorsal core part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12452 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null ES2 CCLE Cell Line Gene CNV Profiles -1.0 -1.76563 Lung squamous cell carcinoma_LUSC_TCGA-56-8628-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.971545 GEO COSMIC Cell Line Gene Mutation Profiles 1.0 null EP300_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.33267 Bed nuclei of the stria terminalis, anterior division, oval nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1273 Depression DisGeNET Gene-Disease Associations 1.0 null HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null integral component of membrane GO Cellular Component Annotations 2015 1.0 null RAB3A_KO_GDS2483_700_mouse_Cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null medial geniculate complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00761 CA2 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.82918 posteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16647 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null shell part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52837 REST_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MHHNB11 CCLE Cell Line Gene Expression Profiles 1.0 1.58486 Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09474 CTCF_WERI-Rb-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2029 CCLE Cell Line Gene Expression Profiles 1.0 1.84966 H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.937764 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS53 CCLE Cell Line Gene Expression Profiles -1.0 -1.81713 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7902-01A-12R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19564 Perturb_13930_OE_DLG2_ERP119345 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 15.1807 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.831169 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35854 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52789 dorsal part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18669 H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lateral posterior nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09969 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA3_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02741 mantle zone of AHy Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84723 NCI-H2347 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYOG ENCODE Transcription Factor Targets 1.0 null CPCN CCLE Cell Line Gene CNV Profiles -1.0 -1.56863 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HMGN3 ENCODE Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNCA_KO_GDS4153_530_mouse_striatum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-520b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053718 UBB_KO_GDS3906_494_mouse_Testis - 21 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22534 JL1 DepMap CRISPR Gene Dependency 1.0 2.34115 SNCA_KO_GDS4153_445_mouse_Striatum - 21 month GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00651 NCIH2887 DepMap CRISPR Gene Dependency 1.0 5.64695 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RU-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS153 CCLE Cell Line Gene Expression Profiles 1.0 1.67561 CDK4_knockdown_225_GSE8866 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.1619 anterior pretectal nucleus, ventral core part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15616 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63491 Brain Lower Grade Glioma_LGG_TCGA-DB-A64W-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.073675 Cortical amygdalar area, anterior part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47972 vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.054167 mantle zone of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61421 H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.24643 LCLC-103H COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.62961 OSC-20 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31594 cytoplasmic part GO Cellular Component Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAPAN-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 TCF12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58982 NCI-H196 COSMIC Cell Line Gene Mutation Profiles 1.0 null olivary pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49635 SIN3A_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02644 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.921348 ubiquitin-like protein transferase activity GO Molecular Function Annotations 2023 1.0 null YKG1 DepMap CRISPR Gene Dependency 1.0 2.58146 CNR_KO_GDS2820_636_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null OCIM2 DepMap CRISPR Gene Dependency 1.0 5.09929 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962854 hsa-miR-520e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 crohn's disease GWASdb SNP-Disease Associations 1.0 0.549747 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I7-06A-22R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03891 Optic Neuritis DisGeNET Gene-Disease Associations 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 polymorph layer of TuPal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36645 KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04491 cellular protein modification process GO Biological Process Annotations 2015 1.0 null LOUCY CCLE Cell Line Gene CNV Profiles -1.0 -1.51993 COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03014 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.30097 Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GDS4791_539_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY ChEA Transcription Factor Targets 2022 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02395 FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056828 JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS454 CCLE Cell Line Gene Expression Profiles 1.0 1.72221 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849617 Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CML-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21867 inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.87336 TAF7_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Olfactory tubercle Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20396 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null REST_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Precommissural nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82072 CORL95 CCLE Cell Line Gene Expression Profiles 1.0 1.78141 HCFC1 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5740-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CSTB_KO_GDS5089_486_mouse_Cerebellum and granule neurons GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ventral part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03982 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31131 Brain Lower Grade Glioma_LGG_TCGA-DU-7300-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05209 CCLFPEDS0008T DepMap CRISPR Gene Dependency 1.0 3.25236 PK45H CCLE Cell Line Gene CNV Profiles 1.0 2.24603 POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2126 COSMIC Cell Line Gene Mutation Profiles 1.0 null VZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.963513 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043215 pyramidal layer of taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.26508 pretectum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14523 CHD1 ENCODE Transcription Factor Targets 1.0 null r11 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18703 type ii diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.432089 Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null principal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40442 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.857507 COV644 DepMap CRISPR Gene Dependency 1.0 2.40809 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.881068 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01308 H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6WP-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AKT1_Activation - 6 week induction_GDS2308_718_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.906976 zinc ion binding GO Molecular Function Annotations 2015 1.0 null rostral paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1682 Perturb_13928_OE_DLG2_ERP119345 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.061401 Brain Lower Grade Glioma_LGG_TCGA-QH-A6X8-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reticular formation of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.91473 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1395 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.92855 H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.96918 Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.0979 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-11A-01R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.138134 lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.55304 ventral entopeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19564 CSTB_KO_GDS5089_169_mouse_Cerebrellum GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null horizontal nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08633 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null plexiform layer of TuStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92786 Zinc finger, RING/FYVE/PHD-type InterPro Predicted Protein Domain Annotations 1.0 null REST_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.16581 NCIH2009 CCLE Cell Line Gene CNV Profiles 1.0 1.5998 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null corticoid layer of TuStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71987 primary motor cortex (area M1, area 4)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.990856 TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null finger TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.734323 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OACP4C COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 NCIH1792 CCLE Cell Line Gene CNV Profiles -1.0 -1.67088 BEN CCLE Cell Line Gene Expression Profiles 1.0 1.98579 parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19889 SMAD4-21741376-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null suboptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82611 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.948312 NCIH2122 CCLE Cell Line Gene Expression Profiles -1.0 -1.59127 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 liminal central gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0007 H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03584 abnormality of the kidney GWASdb SNP-Phenotype Associations 1.0 0.138221 MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null reticular nucleus of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3616 disease GWASdb SNP-Disease Associations 1.0 0.031263 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31131 spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.187391 hsa-miR-376a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TGFBR2_knockout_295_GSE45968 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.68675 mantle zone of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50214 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.834655 PC14 CCLE Cell Line Gene CNV Profiles 1.0 1.53387 SIN3A ENCODE Transcription Factor Targets 1.0 null YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null putamen, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21175 HEP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52251 JUN_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Superior colliculus, motor related, intermediate gray layer, sublayer b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13172 PL18 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_PFSK-1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC70 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 CA4 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02766 PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null CREB1-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Nucleus of the lateral olfactory tract, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84723 Perturb_13039_KD_Tardbp_SRP314028 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.21507 REST_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1 ChEA Transcription Factor Targets 1.0 null dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.39996 caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.901963 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18567 CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null MDAMB415 DepMap CRISPR Gene Dependency 1.0 2.06692 HMCB CCLE Cell Line Gene Expression Profiles -1.0 -2.14406 late endosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.648721 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null intestinal disease GWASdb SNP-Disease Associations 1.0 0.242919 Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849617 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6356-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-302c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.05427 Perturb_172_KD_Asns_SRP119931 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.46691 medial (main) part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05389 POLR2A ENCODE Transcription Factor Targets 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05315 Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1512 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.4229 tobacco use disorder GAD Gene-Disease Associations 1.0 null HLE CCLE Cell Line Gene CNV Profiles -1.0 -1.48383 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33806 striatal part of olfactory tuberculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38711 TE-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53093 Septohippocampal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01494 H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCIH1836 CCLE Cell Line Gene Expression Profiles 1.0 1.51139 mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.28506 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null putamen, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30143 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KON COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-302a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 S117 CCLE Cell Line Gene CNV Profiles -1.0 -1.32154 preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.943896 anterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05539 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041127 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH2227 CCLE Cell Line Gene CNV Profiles -1.0 -1.88143 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.00808 Superior colliculus, motor related, deep gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47197 SW900 CCLE Cell Line Gene CNV Profiles -1.0 -1.71362 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06549 subethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50267 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.894294 Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Duodenum Mucosa Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.27034 Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.73964 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22386 intrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.125449 H3K27me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null intermediate stratum of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.60133 SKMEL1 CCLE Cell Line Gene CNV Profiles 1.0 1.55911 VZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.833514 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.96497 MDST8 CCLE Cell Line Gene CNV Profiles -1.0 -2.13824 RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DAUDI COSMIC Cell Line Gene Mutation Profiles 1.0 null ventral lateral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00849 Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-7637-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ESS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.44923 MAX ENCODE Transcription Factor Targets 1.0 null pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.138134 H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null EGR1 ENCODE Transcription Factor Targets 1.0 null cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01889 KPNYN CCLE Cell Line Gene Expression Profiles 1.0 2.16359 TT2609C02 CCLE Cell Line Gene Expression Profiles -1.0 -2.02285 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 647-V COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 Lateral habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10353 CCFSTTG1 DepMap CRISPR Gene Dependency 1.0 2.35058 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2451 heart GTEx Tissue Gene Expression Profiles 1.0 0.923974 GATA1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNB19 CCLE Cell Line Gene CNV Profiles -1.0 -1.49702 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.846433 inflammatory bowel disease GWASdb SNP-Disease Associations 1.0 0.338196 membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.054108 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4938 cuneiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1517 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r4 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08397 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.210894 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKNSH CCLE Cell Line Gene Expression Profiles 1.0 1.76191 H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null neuroblastoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null UMC-11 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 medial amygdala, anteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.63047 striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.43509 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053149 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null olfactory part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.924895 KM12 CCLE Cell Line Gene CNV Profiles -1.0 -1.32266 Striatum-like amygdalar nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0739 TE14 CCLE Cell Line Gene CNV Profiles 1.0 1.93458 RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.165 ATF2 ENCODE Transcription Factor Targets 1.0 null vesicle membrane GO Cellular Component Annotations 2015 1.0 null Diabetic Nephropathies dbGAP Gene-Trait Associations 1.0 0.156847 layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23855 crohn's disease GWASdb SNP-Phenotype Associations 1.0 0.468803 intermediate stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11101 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null REST_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null periventricular stratum of m2AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18226 Prostate adenocarcinoma_PRAD_TCGA-KK-A8I6-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner SZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.920722 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22443 H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCIH82 DepMap CRISPR Gene Dependency 1.0 2.4092 RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null spanning component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.210894 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null doxorubicin_homo sapiens_gpl570_gse46493 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Uterine Carcinosarcoma_UCS_TCGA-ND-A4W6-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null Violence DisGeNET Gene-Phenotype Associations 1.0 null NCIH660 CCLE Cell Line Gene Expression Profiles 1.0 1.4101 periventricular stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78843 HDAC6 ENCODE Transcription Factor Targets 1.0 null H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 mantle zone of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34355 CAL-85-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.91175 REST_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null NCI-H748 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 inferior olivary complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.89146 LN464 DepMap CRISPR Gene Dependency 1.0 2.34486 spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.04577 episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43452 TFAP2A JASPAR Predicted Transcription Factor Targets 1.0 null H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NM-01A-21R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-373 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 REST_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17232 Infralimbic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18077 NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.301 LTBR_INHIBITION - 27 Day_GDS2005_731_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NH6 CCLE Cell Line Gene Expression Profiles 1.0 2.4087 CA1 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.901082 cell part LOCATE Predicted Protein Localization Annotations 1.0 null artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.064533 H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Clinically Isolated Syndrome DisGeNET Gene-Disease Associations 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.032534 Striatum ventral region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04044 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null pallidal islands of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.23188 REST_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NB1 CCLE Cell Line Gene Expression Profiles 1.0 1.56377 mediodorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.919038 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_13570_KD_Islr_SRP160431 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.951003 vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Postsubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10409 body of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11303 SUZ12 ENCODE Transcription Factor Targets 1.0 null HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_Panc1_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3255 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051336 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28156 Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null deep layers of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0477 multivesicular body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.864907 nucleus of the lateral olfactory tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87253 VZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13011 amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01083 juxtacommissural pretectal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36773 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18629 r5 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41681 H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.906341 Medial amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.30191 Dorsal peduncular area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36773 SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.25584 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61512 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.839038 MYOG_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null commissural pretectal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07582 intermediate stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12684 Osteoporosis DisGeNET Gene-Disease Associations 1.0 null central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03904 MAX_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1385 CCLE Cell Line Gene Expression Profiles 1.0 1.60302 REST_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A875-01A-31R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17036 REST_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytoplasmic vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34013 MFM-223 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null ATM_knockout_74_GSE23116 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.17391 NUGC3 CCLE Cell Line Gene Expression Profiles -1.0 -1.94046 REST_Panc1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K27me3_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06979 abnormality of the large intestine GWASdb SNP-Phenotype Associations 1.0 0.229989 intermediate stratum of JcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16876 H3K27me3_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null integral component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.165697 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4995-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null polymorph layer of TuStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14872 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05873 TKKK DepMap CRISPR Gene Dependency 1.0 2.24688 GABPA ENCODE Transcription Factor Targets 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_Rectal Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Alcohol Abuse DisGeNET Gene-Disease Associations 1.0 null CAL851 CCLE Cell Line Gene CNV Profiles 1.0 1.34288 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27282 GATA3-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null ABC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.42269 HOTHC DepMap CRISPR Gene Dependency 1.0 2.47711 Get-1_Deficiency_GDS2629_161_mouse_embryonic skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null periventricular stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06181 periventricular stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00172 CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04226 93T449 DepMap CRISPR Gene Dependency 1.0 2.74633 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.981874 SF126 CCLE Cell Line Gene CNV Profiles 1.0 1.3542 CHLA15 DepMap CRISPR Gene Dependency 1.0 2.92701 BDCM CCLE Cell Line Gene CNV Profiles -1.0 -1.55054 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18629 REST_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50423 TCF12 ENCODE Transcription Factor Targets 1.0 null ventral anterior nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.869474 COV318 DepMap CRISPR Gene Dependency 1.0 2.31677 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null kidney disease GWASdb SNP-Disease Associations 1.0 0.194227 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.20375 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the intestine GWASdb SNP-Phenotype Associations 1.0 0.170148 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular protein metabolic process GO Biological Process Annotations 2015 1.0 null HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984131 periventricular stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17577 U87MG DepMap CRISPR Gene Dependency 1.0 2.55801 LP1 DepMap CRISPR Gene Dependency 1.0 5.93184 Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1402 POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Abnormalities, Drug-Induced CTD Gene-Disease Associations 1.0 1.1437 H3K27me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bed nucleus of the accessory olfactory tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.59403 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03019 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.36526 REST_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null REST_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SIN3A_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-520d-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 T3M10 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 TE-10 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945753 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.554478 NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09098 MYC_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 1 of PrS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17902 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35422 COLO783 CCLE Cell Line Gene CNV Profiles -1.0 -2.59406 all GWASdb SNP-Phenotype Associations 1.0 0.03409 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.51567 abnormality of the urinary system physiology GWASdb SNP-Phenotype Associations 1.0 0.222492 CBX3 ENCODE Transcription Factor Targets 1.0 null H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.980159 REST ENCODE Transcription Factor Targets 1.0 null MYC_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45845 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043405 COV318 CCLE Cell Line Gene CNV Profiles -1.0 -2.35153 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.22498 H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.79126 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GLC82 CCLE Cell Line Gene CNV Profiles 1.0 1.77052 Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UG-01A-32R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Postsubiculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03649 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08545 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null precommissural pretectal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40958 corticoid layer of TuPal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.01693 MEF-2 MotifMap Predicted Transcription Factor Targets 1.0 null CHD1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09065 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null caudal subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.987808 corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.79354 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.833687 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Islands of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17424 GK_KO_GDS2610_162_mouse_Brown adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43234 superficial stratum of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35775 urinary system disease GWASdb SNP-Disease Associations 1.0 0.194227 facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23366 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null Huntington's Disease_Lymphocyte_GSE8762 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.50656 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null subcuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04464 NCIH1703 CCLE Cell Line Gene CNV Profiles 1.0 1.72214 RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39306 lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03458 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Necrosis CTD Gene-Disease Associations 1.0 1.17202 Zinc finger, RING-CH-type InterPro Predicted Protein Domain Annotations 1.0 null H3K27me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null REST_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.52218 superficial stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10409 transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.824267 CORL279 CCLE Cell Line Gene CNV Profiles 1.0 2.04323 Anterior amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01582 NCIH889 CCLE Cell Line Gene Expression Profiles 1.0 1.44831 HCC44 CCLE Cell Line Gene CNV Profiles 1.0 1.63756 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040679 REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH520 CCLE Cell Line Gene CNV Profiles -1.0 -1.4664 SMARCA4 ChEA Transcription Factor Targets 1.0 null HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null diabetic nephropathies GAD Gene-Disease Associations 1.0 null RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12724 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35952 H3K27me3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-302e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.078478 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.49882 cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.231102 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cortical amygdalar area, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62211 secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.19744 CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21621 EGR1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cuneus, left, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0647 hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85527 H3K4me1_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null medial amygdala, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.09478 abnormal renal physiology GWASdb SNP-Phenotype Associations 1.0 0.243807 cell part GO Cellular Component Annotations 2015 1.0 null KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6838 mantle zone of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60147 body of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0009 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35422 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.16847 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.41182 H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09132 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13880_KD_MYCN_SRP073460 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.81937 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.061433 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12663 plexiform layer of TuPal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.25075 cytoplasmic membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.054687 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11081 mantle zone of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1242 Perturb_13844_KD_Hs6st1_SRP371980 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.51106 Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10054 KDM4A ENCODE Transcription Factor Targets 1.0 null SUPM2 DepMap CRISPR Gene Dependency 1.0 2.47947 medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1233 HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19488 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21206 mediodorsal nucleus of thalamus_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.996337 Ankylosing Spondylitides_macrophage_GSE11886 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.64104 orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.824096 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null tail of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.988423 posteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14184 orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07792 H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null chronic colitis GWASdb SNP-Phenotype Associations 1.0 0.355555 Presubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18343 M040416 DepMap CRISPR Gene Dependency 1.0 2.97433 Periventricular hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02426 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22515 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Radiation-Induced Cancer DisGeNET Gene-Disease Associations 1.0 null H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null lateral preoptic nucleus, PO2 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4724 Perturb_18496_KD_LINC00881_SRP362016 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.07657 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20375 ligase activity GO Molecular Function Annotations 2015 1.0 null anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05267 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A814-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16908 parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.51215 Superior colliculus, motor related, deep white layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.61439 Periventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7314 posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.45696 glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.296631 Psychological Distress DisGeNET Gene-Disease Associations 1.0 null cytoplasmic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.054108 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null globus pallidus, external segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17082 Abnormalities, Multiple CTD Gene-Disease Associations 1.0 1.13689 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.870119 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H647 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCAR-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null inferior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12116 mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.89049 inflammation of the large intestine GWASdb SNP-Phenotype Associations 1.0 0.355555 Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null golgi apparatus part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.081179 MON DepMap CRISPR Gene Dependency 1.0 4.70325 primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.27819 principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.969933 KPNRTBM1 CCLE Cell Line Gene Expression Profiles 1.0 3.4076 layer 2 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.9415 limb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.360036 ubiquitin-protein transferase activity GO Molecular Function Annotations 2023 1.0 null medial (fastigial) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07168 RBL1_KO_GDS1932_739_mouse_Neurospheres GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null FURIN_Deficiency_GDS3512_568_mouse_T-cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2862-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-376b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.79298 Perturb_4490_KO_Pantr2_SRP390021 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.0468 cerebellum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11144 type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.794247 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33562 1321N1 CCLE Cell Line Gene Expression Profiles -1.0 -1.58798 TEAD4 ENCODE Transcription Factor Targets 1.0 null primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.55912 ion binding GO Molecular Function Annotations 2015 1.0 null Pretectal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79735 dorsolateral part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1512 SKNDZ CCLE Cell Line Gene Expression Profiles 1.0 1.35252 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849617 Intralaminar nuclei of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08806 MS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HUH-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.91806 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null MYOG_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12103 POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.056163 superficial stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.26508 abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.280975 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.924191 anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.915281 REST_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW1783 CCLE Cell Line Gene CNV Profiles -1.0 -1.38743 abnormality of the abdomen GWASdb SNP-Phenotype Associations 1.0 0.047372 amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02291 abnormality of the abdominal organs GWASdb SNP-Phenotype Associations 1.0 0.051406 magnocellular superficial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4252 Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-34-2600-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86952 H3K36me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 1 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71416 MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13354 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04818 MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1599 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 CLPP_KO_GSE40207_394_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hsa-miR-302b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 H3K23me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34146 dorsolateral IC periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78843 dorsal part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49952 hsa-miR-520a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.870119 germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.485156 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null REST_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-302d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cytoplasmic part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 DKMG DepMap CRISPR Gene Dependency 1.0 5.42969 lateral part of preisthmic periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18177 REST_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Posterior pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92324 dorsofrontal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.60416 SRY JASPAR Predicted Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.905087 NOS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58181 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849617 medial amygdala, anterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28609 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6666-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Medial amygdalar nucleus, anteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.80072 CTCF_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31594 Olfactory tubercle, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09556 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.194006 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lambdoid septal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27822 REST_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40392 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.58355 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.31214 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49853 EP300 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64818 H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CHP134 DepMap CRISPR Gene Dependency 1.0 2.08382 extrinsic cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.24996 COLO-783 COSMIC Cell Line Gene Mutation Profiles 1.0 null OVKATE COSMIC Cell Line Gene Mutation Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of m2AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15071 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null COR-L95 COSMIC Cell Line Gene Mutation Profiles 1.0 null REST_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50214 cytoplasmic vesicle membrane GO Cellular Component Annotations 2015 1.0 null MAPK14_knockout_13_GDS2693 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.9121 end stage renal failure GWASdb SNP-Disease Associations 1.0 0.794247 H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-93-7348-01A-21R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.675357 H3K9me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 3.17073 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03604 abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.301941 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null supragenual nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06763 Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macromolecule modification GO Biological Process Annotations 2015 1.0 null superficial stratum of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41466 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SHSY5Y CCLE Cell Line Gene Expression Profiles 1.0 2.65491 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042828 gastrointestinal inflammation GWASdb SNP-Phenotype Associations 1.0 0.262217 H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate part of the arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23493 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4876 lateral part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60203 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8108 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00763 REST_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VG-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1857 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17138 CTBP2 ENCODE Transcription Factor Targets 1.0 null VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.936824 endosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.378122 H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.91175 CTCF_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CSTB_KO_GSE47516_677_mouse_mouse cerebellum P7 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Orbital area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09553 VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16315 inner SZ in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01548 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3ac_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.64921 HT1080 DepMap CRISPR Gene Dependency 1.0 3.15266 MSTN_KO_GDS3637_439_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27745 Fastigial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12168 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.906341 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.43509 cerebellar nuclei of CbV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0727 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.9898 MTF2 ChEA Transcription Factor Targets 1.0 null U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945753 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.9976 SKNDZ DepMap CRISPR Gene Dependency 1.0 2.82835 Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58662 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null LN340 CCLE Cell Line Gene CNV Profiles -1.0 -1.78789 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29827 cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.48159 HDAC6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null reticular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1663 amygdaloid complex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02007 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12011 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02361 H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null S117 DepMap CRISPR Gene Dependency 1.0 6.67661 Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.26378 mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.27883 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null transition metal ion binding GO Molecular Function Annotations 2015 1.0 null Superior colliculus, motor related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06914 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LNCAPCLONEFGC DepMap CRISPR Gene Dependency 1.0 3.06429 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31594 rhombomere 11 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13473 HO-1-U-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 RCOR1 ENCODE Transcription Factor Targets 1.0 null H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null chronic kidney failure GWASdb SNP-Disease Associations 1.0 0.454009 GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Arcuate hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42948 secretory granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.086851 Medial amygdalar nucleus, posterodorsal part, sublayer a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84196 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20237 Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEL DepMap CRISPR Gene Dependency 1.0 2.64565 ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05024 Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A87H-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null gastrointestinal system disease GWASdb SNP-Disease Associations 1.0 0.067043 dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30001 Nucleus of the optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00833 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42212 SCC4 CCLE Cell Line Gene CNV Profiles 1.0 1.80341 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ventral juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16976 HS 852.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46156 cation binding GO Molecular Function Annotations 2015 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962854 NCI-H1869 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 CHD2 ENCODE Transcription Factor Targets 1.0 null membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042693 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1703 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21791 superior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13565 Medial amygdalar nucleus, posterodorsal part, sublayer b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16951 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LN18 CCLE Cell Line Gene Expression Profiles -1.0 -1.68341 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null WM1799 CCLE Cell Line Gene CNV Profiles 1.0 1.37235 CORL24 CCLE Cell Line Gene Expression Profiles 1.0 1.43575 H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null VMRC-LCD COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.690584 RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.062537 NCIH2081 CCLE Cell Line Gene Expression Profiles 1.0 1.39312 H3K27me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.930378 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H9 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.36266 H3K27me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null U251MG CCLE Cell Line Gene CNV Profiles -1.0 -1.41723 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.939708 Dorsal peduncular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.81235 intermediate stratum of m2AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1517 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null CHP126 CCLE Cell Line Gene Expression Profiles 1.0 1.35795 NCI-H716 COSMIC Cell Line Gene Mutation Profiles 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventral tuberomammillary nucleus, superficial part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10482 shell of SCH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35651 H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.48625 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.39167 ZNF143 ENCODE Transcription Factor Targets 1.0 null H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the endocrine system GWASdb SNP-Phenotype Associations 1.0 0.137137 SH4 DepMap CRISPR Gene Dependency 1.0 4.21361 Dorsal peduncular area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 4.44139 trans-golgi network COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.665962 NCI-H2009 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44616 NO-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null JHU-029 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11386 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inner SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09184 NCI-H82 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984131 REST_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cortical amygdalar area, anterior part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74329 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.65493 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.966319 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4483 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 REST_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CA3 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21296 outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00382 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10227 CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042635 cytoplasmic vesicle part GO Cellular Component Annotations 2015 1.0 null superficial stratum of Pal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73282 A673 CCLE Cell Line Gene CNV Profiles -1.0 -1.42062 REST_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Taenia tecta, dorsal part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32311 HS852T CCLE Cell Line Gene CNV Profiles 1.0 2.26368 COGN305 DepMap CRISPR Gene Dependency 1.0 2.48445 JJN-3 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945753 outer SZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.849586 HELA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.89301 LUDLU1 CCLE Cell Line Gene CNV Profiles 1.0 1.56354 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reticular formation of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62184 Retrosplenial area, lateral agranular part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27135 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.325753 COLO-205 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11913 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.88009 YD38 DepMap CRISPR Gene Dependency 1.0 2.35194 MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CLPP_KO_GDS4791_375_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12663 MJ DepMap CRISPR Gene Dependency 1.0 2.69073 mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.51519 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-124-3p MiRTarBase microRNA Targets 1.0 null female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.212936 lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.80931 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047388 deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.912275 alar part of terminal hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11778 H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null kidney failure GWASdb SNP-Disease Associations 1.0 0.387883 brain GTEx Tissue Gene Expression Profiles 1.0 1.11667 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.82844 FOXA1 ENCODE Transcription Factor Targets 1.0 null mediodorsal nucleus of thalamus_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.71095 Perturb_2948_KD_Hnrnpk_DRP004738 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.88669 posteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23046 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Post-Traumatic Stress Disorder DisGeNET Gene-Disease Associations 1.0 null morphological abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.103636 Lung squamous cell carcinoma_LUSC_TCGA-85-8287-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.879313 lateral subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19675 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.51704 RAGE_knockout_267_GDS3755 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.51933 H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null myocardial infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.350452 pallidal part of olfactory tuberculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72128 JHOM2B CCLE Cell Line Gene Expression Profiles -1.0 -1.90287 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null DMS79 CCLE Cell Line Gene Expression Profiles -1.0 -1.51014 E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06813 eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A59E-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.35557 RAD21 ENCODE Transcription Factor Targets 1.0 null HS281T CCLE Cell Line Gene Expression Profiles -1.0 -1.75805 Cortical amygdalar area, posterior part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00148 RPE1SS119 DepMap CRISPR Gene Dependency 1.0 3.45209 abnormality of the urinary system GWASdb SNP-Phenotype Associations 1.0 0.113347 647V CCLE Cell Line Gene CNV Profiles 1.0 1.51956 molecular_function GO Molecular Function Annotations 2015 1.0 null A3KAW CCLE Cell Line Gene CNV Profiles -1.0 -1.39448 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SHSY5Y DepMap CRISPR Gene Dependency 1.0 4.32396 superficial stratum of AHy Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84902 NCIH2110 CCLE Cell Line Gene CNV Profiles 1.0 1.56624 REST_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041032 NCI-H1734 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 Anterior pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98307 muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.053852 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null functional abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.186708 dorsal part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12383 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4876 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.91564 protein metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_6233_KO_Ugt8_SRP073495 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.78346 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.134002 forelimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.430312 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 inferior olive, dorsal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.906714 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868639 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3641 SAP30 ENCODE Transcription Factor Targets 1.0 null GATA1 ENCODE Transcription Factor Targets 1.0 null HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34304 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.33727 H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null binding GO Molecular Function Annotations 2015 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SKNBE2 CCLE Cell Line Gene Expression Profiles 1.0 2.21996 posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17582 cellular_component GO Cellular Component Annotations 2015 1.0 null YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5769-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.53736 EZH2 ENCODE Transcription Factor Targets 1.0 null HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39517 H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IMR32 CCLE Cell Line Gene Expression Profiles 1.0 1.51145 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03545 H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OELE CCLE Cell Line Gene Expression Profiles -1.0 -1.61041 lateral part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08856 abnormality of the upper urinary tract GWASdb SNP-Phenotype Associations 1.0 0.138221 RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.21902 Rectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ESS1 CCLE Cell Line Gene Expression Profiles -1.0 -1.47274 HEL9217 DepMap CRISPR Gene Dependency 1.0 2.0944 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.61168 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23653 inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1823 H3K9me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null VZ in caudal cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.825985 SK-MG-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 HCC-366 COSMIC Cell Line Gene Mutation Profiles 1.0 null muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.053082 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null U343 CCLE Cell Line Gene CNV Profiles -1.0 -1.91277 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02175 semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.177285 NCIH1781 CCLE Cell Line Gene CNV Profiles 1.0 1.42551 hsa-miR-323-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 lateral part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61477 NCI-H1703 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-520c-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nephropathy GWASdb SNP-Phenotype Associations 1.0 0.690584 Inflammation CTD Gene-Disease Associations 1.0 1.06188 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00805 CLPP_KO_GDS4791_106_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17326 H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KPNYN DepMap CRISPR Gene Dependency 1.0 2.72483 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05024 SIHA CCLE Cell Line Gene CNV Profiles 1.0 1.47818 RBBP5 ENCODE Transcription Factor Targets 1.0 null REST_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-372 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 REST_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13138 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57754 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 LTBR_INHIBITION - 35 Day_GDS2005_732_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.28906 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02768 lateral tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46371 MTF2-20144788-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GATA3_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null deep gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5326 Medial amygdalar nucleus, anterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66708 H3K4me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.881118 dorsolateral SC part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.24775 cerebellar cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.836774 FOSL1 ENCODE Transcription Factor Targets 1.0 null Metastatic Non-Small Cell Lung Cancer DisGeNET Gene-Disease Associations 1.0 null medial amygdala, posterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20259 H3K27me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral IC periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47039 HDAC2_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.945753 abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.073957 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null LK-2 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 LTBR_INHIBITION - 3 Days_GDS2005_730_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.58953 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01154 LCLC103H CCLE Cell Line Gene CNV Profiles 1.0 1.47065 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42287 Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC-44 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 H3K27me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-2A-A8VV-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.59423 Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58451 HDLM2 CCLE Cell Line Gene CNV Profiles -1.0 -2.13572 H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Orbital area, medial part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38755 PDE10A_KO_GDS4542_291_mouse_striatum GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null globus pallidus, internal segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.867597 VZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09501 HCC2157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.79513 ethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4767 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4994-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary metabolic process GO Biological Process Annotations 2015 1.0 null H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FOSL1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane part GO Cellular Component Annotations 2015 1.0 null H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null abducens nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.835216 LU-134-A COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 Perturb_13915_KD_SLC45A4_SRP173763 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.06723 Nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96581 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984131 SKNFI CCLE Cell Line Gene Expression Profiles 1.0 1.90628 reticular formation of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88727 protein modification process GO Biological Process Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r10 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11213 H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48603 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.065 Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taenia tecta, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71451 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.903563 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.78651 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27072 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05342 BICR31 CCLE Cell Line Gene CNV Profiles -1.0 -1.48961 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15368 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null periventricular stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08655 CSTB_KO_GDS5089_565_mouse_cerebellum and granule neurons GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null AKT1_OE_GDS2308_499_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null integral component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.138505 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HO-1-N-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.19863 Cortical amygdalar area, posterior part, lateral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24427 E2F6 ENCODE Transcription Factor Targets 1.0 null H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.075601 MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64448 Medial pretectal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17527 CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null catalytic activity GO Molecular Function Annotations 2015 1.0 null SKMES1 CCLE Cell Line Gene CNV Profiles -1.0 -1.99778 inner SZ in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.875855