association	dataset	threshold value	standardized value
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17309
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7578
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.8026
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX1_CDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17667
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6462
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40714
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BMPR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22771
HS-Sultan cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.649
MAP3K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62496
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9385
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RSC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86179
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0642
Fascioliasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50611
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	89.0716
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52639
SMU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5462
FOXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86141
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05453
GSE109285_3_v_4_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17373
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00774
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	206.692
Anal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
PMC7725876-Table_2.xls-Sheet1-Table_2_v1_DEGs_in_the_BESC_were_treated_with_LPS_compared_with_PBS_control_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55362
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42911
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47307
Anus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56183
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
VPS26C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16129
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.029
GSE211474,GSE212779_8_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.649
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1896
Secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.086
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5303304-13073_2017_407_MOESM4_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S3_Genes_differentially_expressed_by_24h_RA_and_48h_Dox_co-treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
FOXE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19846
Brain_CT2_CBI 306	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13697
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22492
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
CAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61859
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153443_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TIMM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00196
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.6153
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45211
GSE86507,GSE86509_3_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-7-TBX2_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
FAM98A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22399
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56549
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10933
FBXO41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85808
GSE205163,GSE205164_9_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02775
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33348
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61893
Sputum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07015
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.98168
TFB2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29618
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	154.934
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
PMC10753177-Table_3.xlsx-Upregulated-Table_S3_Overlap_among_gene_sets_differentially_regulated_after_NR5A1_beta-catenin_knockdown_in_H295R_ACC_cells_NR5A1	Rummagene Transcription Factor Associations 2026	1.0	null
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66628
GSE169263_1_v_0_armc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38959
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71919
Anal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
NCAPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54793
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86501
Brain_CT2_CBI 306	HuBMAP ASCT+B Annotations	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69393
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27473
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2015
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
496100542_PCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0795
MEL-JUSO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.15196
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8411
PMC9999213-mmc3.xlsx-DEGs_CSc-DEA_NB_MSC_EC_CSc_vs_NB_CSc_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60619
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
496100334_PCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29925
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9942993-pone.0281645.s002.xlsx-AR-as_adaptive-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02243
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0569
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-SALL2_targets-target_gene_SALL2	Rummagene Transcription Factor Associations 2026	1.0	null
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22739
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01611
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00917
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	248.959
VAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21432
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_lost-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KIAA1522	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81421
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPP1R2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.663
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66335
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11375
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
MRPS18C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4664
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35932
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
RPS19BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76854
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07153
CFAP418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1735
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant intellectual developmental disorder 44	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
ZFPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24725
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9879
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.649
TAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68247
GSE84922,GSE84924_0_v_3_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
trans-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.657
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Breast disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.649
chr5_16382388_T_A_b38	GTEx eQTL 2025	1.0	1.02709
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9686
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78111
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-52-PRDM13_PRDM13	Rummagene Transcription Factor Associations 2026	1.0	null
Columella	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6184
GSE201401_2_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.649
GSE161295_4_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Multivesicular body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.61
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8714
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3459
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74041
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18146
Ubiquitin activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
AKR7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30068
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr5_16110322_G_A_b38	GTEx eQTL 2025	1.0	1.07867
PMC6078853-molce-41-7-695-suppl2.xlsx-Sheet1-Table_S1_Genes_exhibiting_two-fold_changes_in_expression_between_WT_and_CTCF_KO_otocyst_with_FDR_less_than_0_05_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1287
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mast-cell leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6743
Chitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
TM7SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63371
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_lost-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
THAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57825
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.699
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE224970,GSE224971_1_v_0_sap30_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ZNF358_ZNF358	Rummagene Transcription Factor Associations 2026	1.0	null
BRCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24036
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74764
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71534
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31829
VWA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03446
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IgD B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.554
POLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55579
IgD immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.734
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38577
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
TMED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77921
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.784
496100581_TCx_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20566
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158320,GSE183351_0_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08449
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cysteine synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.146
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7971
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0592
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.64
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.75
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2754
TXNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62327
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30648
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	195.371
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50078
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cri-Du-Chat syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
GSE210655_3_v_6_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PLD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37428
ADCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07134
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
CASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48667
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1093
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81892
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	172.199
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9942993-pone.0281645.s002.xlsx-AR-as_adaptive_as_lost-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04445
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
PMC9574515-mmc1.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15386
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3317
CARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31956
Melanosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
RAB39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86868
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1434
GSE258991_5_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86042
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
MLST8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36832
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07308
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120595_0_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31799
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	208.071
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51671
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9865
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40493
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Breast carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.649
PPP1R3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76875
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NUP210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04282
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3387
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4566
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17078
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02199
IER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64938
GINS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31882
GSE102870_5_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal dominant intellectual developmental disorder 48	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.8647
GSE186440,GSE186443_1_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_4_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5303304-13073_2017_407_MOESM3_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S2_Genes_differentially_expressed_by_24h_RA_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22333
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neuroblastoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AQR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67233
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8007
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55128
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9574515-mmc2.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130401_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3155
PMC9942993-pone.0281645.s002.xlsx-AR-as_adaptive-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37225
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1373
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.649
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8036
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02787
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C9orf78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69622
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08864
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4364
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-117-IRX2_IRX2	Rummagene Transcription Factor Associations 2026	1.0	null
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27697
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9135
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	154.77
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5833
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09031
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13001
NEDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19907
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
retromer, cargo-selective complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
ACADS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58627
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3239
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04471
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9574515-mmc2.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6743
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54122
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67904
GSE161295_2_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
GSE193334_1_v_0_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22555
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.958
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4363
PMC6961462-NIHMS1544104-supplement-Sup_Tab.xlsx-Sup_Table_3_a-Supplementary_Table_3_Genes_Regulated_by_A_MYB_in_Humans_and_Macaques_Bold_genes_with_reduced_expression_in_Group_3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33956
PMC9999213-mmc3.xlsx-DEGs_CSc-DEA_NB_MSC_CSc_vs_NB_CSc_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.26942
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8726
ELP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00673
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72246
SH-EP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
archaeal-type flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
ZNF160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08088
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14575
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9067
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GLMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58443
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
Otulipenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3542
PPP4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05833
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18845
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08218
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7815
RAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20888
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
iron-sulfur cluster transfer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.536
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6463
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06479
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59391
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31988
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Buffy coat cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3459
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23535
DONSON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37215
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71383
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LMX1B_LMX1B	Rummagene Transcription Factor Associations 2026	1.0	null
Thoracic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.649
PEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40591
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
LAMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08024
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	154.882
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02574
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LUZP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12191
ZNF672	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20252
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69131
Large intestine adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9624
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-45-ZIC1_ZIC1	Rummagene Transcription Factor Associations 2026	1.0	null
RAD51C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.295
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7414
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07559
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34559
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18729
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EXOSC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56847
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62993
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9209
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8883
GSE179002_0_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00749
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18461
GSE210101,GSE210114_11_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF526	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45339
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98174
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56425
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54964
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE156708_1_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80061
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16886
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4527
UTP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13917
HSPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32775
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_11_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7678
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210655_3_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
PMC9942993-pone.0281645.s002.xlsx-AR-as_adaptive_as_lost-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Ms	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
GSE211128_7_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16645
Derlin-1 retrotranslocation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
RIOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50654
Golgi apparatus subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.631
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8665
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
KNOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6446
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.561
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58011
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF474	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23856
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9129
ITPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01392
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0179
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	216.579
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8228
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF831	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38296
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.389
ZNF799	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07406
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
Outer acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9003
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01539
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3721
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-REL_REL	Rummagene Transcription Factor Associations 2026	1.0	null
Thoracic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.649
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.649
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3489
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF699	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45142
BRCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44454
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
ONECUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0024
AMMECR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65787
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5673
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35568
GSE206870,GSE206872_3_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46054
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	163.77
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.724
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12183
PMC11625982-AJH-100-10-s001.pdf-77-GLI2_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
CHMP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68321
PMC9574515-mmc1.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95632
Criduchat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.32
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8129
Pigment granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2289
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221101_1_v_0_hopx_human	RummaGEO Gene Perturbation Signatures	-1.0	null