association	dataset	threshold value	standardized value
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FKBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74555
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58453
genotype	GeneRIF Biological Term Annotations	1.0	null
insulin-responsive compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.186708
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0324
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4251
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17723
PMC8851354-Table_2.xlsx-Genes_reg_by_FUS-DDIT3-Supplementary_Table_2_Genes_significantly_regulated_by_FUS-DDIT3_expression_in_HT1080_cells_adjusted_p-value_0_05_and_log2_Fold_change_1_or_-1_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11535_KD_SOX2_SRP235264	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.63523
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01856
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918015
GTEX-PSDG-1626-SM-48TCQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.873343
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947873
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18387
BRD-K77320034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15931
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22324
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07299
Leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
BRD-K12397820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62194
BRD-K69872823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11152
PMC11244912-media-3.xlsx-Sheet2-ESR1_mutation_E2_Co-UP_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49691
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28883
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	1.97891
BRD-K30853940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06526
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03655
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.576747
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16443
CRCGN014_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16121
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8635
GSE202434,GSE202438_15_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BICDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40513
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_6583_KO_Setd1b_SRP308727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9376
BSPRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82643
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.62685
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.84073
Infertility, Female	CTD Gene-Disease Associations	1.0	1.11741
BRD-K13927197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08354
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205021_3_v_1_fenofibrate_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25497
BRD-K59182232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41543
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4801
GSE87299_2_v_3_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.951
RBBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21282
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873785
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62661
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00586
provide	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
organonitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SW620_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	4.52695
BRD-K45563993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03934
BRD-K23333192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90259
FOS	ENCODE Transcription Factor Targets	1.0	null
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31301
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3LY-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Embryogenic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.3045
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Kidney Chromophobe_KICH_TCGA-KN-8424-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8851354-Table_5.xlsx-Ruxolitinib_reg_FD-bound-Supplementary_Table_5_Genes_regulated_by_ruxolitinib_that_are_FUS-DDIT3_targets_in_MLS_402-91_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4134
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74886
key	GeneRIF Biological Term Annotations	1.0	null
GTEX-NPJ8-0226-SM-48TBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K90918886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08438
HDAC3_KO_GDS4886_29_mouse_heart - 6 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K27092365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10171
BRD-K63065496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06473
Spore wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
Sclerenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.309
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.865029
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83619973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22156
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75089
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Diseases of metabolism	Reactome Pathways 2024	1.0	null
hacat	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53033
COPI-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.898
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40271
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pupa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
Phosphatidylinositol transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
BRD-K10989535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17074
BRD-K00446585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46762
Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43306617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30347
Dorsum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
Mammary Tumorigenesis	DisGeNET Gene-Phenotype Associations	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.540294
PMC7226524__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.277
Methylation pathways	WikiPathways Pathways 2024	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	2.13772
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839236
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889287
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58496
Steatohepatitis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.803352
Personality Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.236
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53110645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90461
NCIH292	DepMap CRISPR Gene Dependency	1.0	2.8527
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12795
hsa-miR-1343	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
adult ovary	HPM Cell Type and Tissue Protein Expression Profiles	1.0	1.14787
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
WM115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45743
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFON-0926-SM-4LVMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93495
BRD-K07336866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50532
RPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16886
Aneuploidy	CTD Gene-Disease Associations	1.0	1.0637
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K37760996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23108
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.738
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13757
liver/biliary system phenotype	MPO Gene-Phenotype Associations	1.0	null
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34027
methionine catabolic process	GO Biological Process Annotations 2025	1.0	null
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18211442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11642
GSE224969,GSE224971_3_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2837
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34724
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IR-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTP4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29158
Carcinoma	CTD Gene-Disease Associations	1.0	1.32637
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67056
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.089
Osteolysis_Leukocyte - Lymphocyte - B-Lymphocyte - Plasma Cell (MMHCC)_GSE755	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52756
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13116
imaginal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.265725
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.069
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40587
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03856
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11022_KO_Rabl2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.37288
LS1034	CCLE Cell Line Gene Expression Profiles	1.0	1.44087
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.54062
dietary	GeneRIF Biological Term Annotations	1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287092
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.65256
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56588599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06909
UBXN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54147
JHH7	CCLE Cell Line Gene Expression Profiles	1.0	1.46036
HCC70	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.39267
SOX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93574
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64461
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087972
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
L-Methionine	DrugBank Drug Targets	1.0	null
Argininosuccinic aciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47514
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.62869
Alcohol Or Other Drugs Use	DisGeNET Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCA1_Knock-in_GDS1756_231_mouse_Cerebellum tissue - 4 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
abnormality of amino acid metabolism	HPO Gene-Disease Associations	1.0	null
Diabetic Neuropathy_Sciatic Nerve_GSE11343	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.58164
BRD-K83049611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06718
Perturb_10834_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.05539
HCC1143	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88015
Electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
abnormal inflammatory response	MPO Gene-Phenotype Associations	1.0	null
ATP	MW Enzyme Metabolite Associations	1.0	null
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00362
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32816
USP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44717
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
tricarboxylic acid cycle enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.183328
DOHH-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56979
PMC8350598-NIHMS1728503-supplement-Table_S3.xlsx-Upregulated_by_SMAD4-Gene_Symbol_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5841
SKMEL2	CCLE Cell Line Gene Expression Profiles	1.0	2.12135
PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
hsa-miR-3190	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K61144709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14289
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940189
Infertility, Male	CTD Gene-Disease Associations	1.0	1.35502
LU65	DepMap CRISPR Gene Dependency	1.0	3.72727
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83254798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30079
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.64712
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12157
Caryopsis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.344
pontine reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827432
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908906
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49778
U2 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Rkip1_KO_GDS4331_15_mouse_C57BL/C pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.411631
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
C3A	GDSC Cell Line Gene Expression Profiles	1.0	3.60177
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17568
PMC9086029__F7	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_11214_KO_Cyp2e1_SRP355413	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.96954
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08016
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88481
Weight Loss	CTD Gene-Disease Associations	1.0	1.47736
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16408
Ubp3-Bre5 deubiquitination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
BRD-K36713925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19221
Forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.477
Photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.597
bisphenol A	CTD Gene-Chemical Interactions	1.0	null
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88695
bj	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053851
Cholestasis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47039
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8273
genetic	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880156
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27657
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
FOXA2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.69867
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23457
Imago	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
Perturb_10356_KD_BRD4_SRP093774	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82919
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70625
Cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.396
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	2.00002
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14802
Perturb_818_KO_BCL7A/BCL7B/BCL7C_SRP345839	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16086
NEPRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1491
Pulp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.865
BRD-K34910830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25194
Lsm2-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
CRCGN008_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0093
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999343
GTEX-RUSQ-2026-SM-4GIAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
inborn	GeneRIF Biological Term Annotations	1.0	null
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2067
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06277
Fatty Liver	DisGeNET Gene-Disease Associations	1.0	null
Perturb_8323_KD_INO80_SRP103083	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.47526
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42332
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS936T	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
TCF7L2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66277
BRD-K82882121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30575
BRD-K30921693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37672
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC9437808-mmc3.xlsx-IPA_Upstream_regulators-IPA_Upstream_regulator_analysis_Up_regulated_genes_following_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Non-Alcoholic Fatty Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
recombinant	GeneRIF Biological Term Annotations	1.0	null
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.89325
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6362
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05407
HEYA8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74939
eight	GeneRIF Biological Term Annotations	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
19061838-TableS3	GeneSigDB Published Gene Signatures	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20185
OCIM2	DepMap CRISPR Gene Dependency	1.0	2.46506
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.843766
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
Palpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.225
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.557629
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
MKN28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hypermethioninemia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K29543978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6552
auf1	GeneRIF Biological Term Annotations	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3913
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS746T	CCLE Cell Line Gene CNV Profiles	1.0	1.75604
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.158434
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9831
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.96869
BRD-K67319345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03898
BRD-K49094605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31511
BRD-A53381587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11795
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-PWCY-0826-SM-48TCR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_11172_KO_Klf15_SRP186285	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.59497
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260945
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16922
Perturb_11237_KO_Thbs1_SRP164677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.33738
IM-9	GDSC Cell Line Gene Expression Profiles	1.0	2.27939
vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.420004
Atrophy	CTD Gene-Disease Associations	1.0	1.62579
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.738
Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25707
EGR1-23403033-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37953
RCCFG2	DepMap CRISPR Gene Dependency	1.0	3.62537
BRD-K88974575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40332
BRD-K29802952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41691
Perturb_11103_KO_Depdc5_SRP219943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.8099
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
Biological oxidations	Reactome Pathways 2024	1.0	null
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.91685
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
barrier septum	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.16184
DRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08018
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)	Reactome Pathways 2014	1.0	null
BRD-K55453160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01235
BRD-K85292767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23874
HCC1954	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01757
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72145
(S)-Zopiclone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
Hyperargininemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
Fatty acid synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.167
BRD-K15474464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88784
Perturb_11046_KO_Ube2e2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.07992
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K02688026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21558
BRD-K07755570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54669
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29409
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of methionine metabolism	HPO Gene-Disease Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56068
hsa-miR-4701-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90756713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40237
BRD-K22875057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1445
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hep-G2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.001
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.016
BRD-K22651517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22355
Nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21269
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
BRD-K75584297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12613
arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289938
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Set1C/COMPASS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.175
ESR1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32186
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D2REFED4h_641_AR-D-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.300682
BRD-K09160804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34113
cos1	GeneRIF Biological Term Annotations	1.0	null
BRD-K65245206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.545
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054751
lb224	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.458
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830179
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
represents	GeneRIF Biological Term Annotations	1.0	null
rats-wistar	Phosphosite Textmining Biological Term Annotations	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45203
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Carcinoma Breast	DisGeNET Gene-Disease Associations	1.0	null
GSE210655_1_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.828
Brain Diseases	CTD Gene-Disease Associations	1.0	2.88009
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12088
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8168
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
autosomal	GeneRIF Biological Term Annotations	1.0	null
bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.237706
FTH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02618
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z3-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Opioid Use Disorder	DisGeNET Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.244
glycosyl compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842944
Multiple synapse bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
BRD-K64553072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33845
Neutropenia	CTD Gene-Disease Associations	1.0	1.08655
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Lateral root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.288
folate	GeneRIF Biological Term Annotations	1.0	null
spleen_3d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02605
Adventitious root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14147
Mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.493
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01783
Hypermethioninemia	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930863
GSE203308_6_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nicotine_mus musculus_gpl1261_gse31004	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875588
BRD-K18601936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11071
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39424
Glucosidase II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01654
Plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
liver_d	HPA Tissue Sample Gene Expression Profiles	1.0	2.01495
BRD-K00882360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25196
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG7-2426-SM-3GIL2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-A42246453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25346
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10197_KD_FIP1L1_SRP251753	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.719
Fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.127
GSE131887_1_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CDY2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10769
DDX55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48762
647V	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59379
Glycine N-methyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.275
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2094
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066488
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Clear cell acanthoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
HDAC3_KO_GDS4886_66_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Metabolism of ingested SeMet, Sec, MeSec into H2Se	Reactome Pathways 2024	1.0	null
HOXC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15686
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.672
CRCGN013_HEPG2_24H:I15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28752
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71521842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30052
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04211
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19261
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bosentan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_3_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K25702540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89904
Gravid adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.355
TST	MSigDB Cancer Gene Co-expression Modules	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36689
hsa-miR-486-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2987
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82115
Plastid thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
Urea cycle disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.823
Leptospirosis	DisGeNET Gene-Disease Associations	1.0	null
Primary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.257
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LH-86 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42071
Aflatoxin B1	CTD Gene-Chemical Interactions	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Metabolism of amino acids and derivatives	Reactome Pathways 2014	1.0	null
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.714189
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18401
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08236
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1591
Coma	CTD Gene-Disease Associations	1.0	1.24905
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10393
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08979
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9107
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08195
Sin3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.60477
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8186
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Citrullinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.002
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08715918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69278
Congenital Malformation Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35226
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.16784
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRS4_KO_GDS1219_306_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
MG63	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72582
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.242
BRD-K08966355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65556
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cystathioninuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.2352
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.858503
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22021
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	0.856635
hsa-miR-3916	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
EGR1-23403033-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K25075258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56039
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K66463856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.84148
BRD-K27228812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14873
MZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35839
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936126
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.073
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02874
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
stroke	GeneRIF Biological Term Annotations	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04528
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14823
Hyperlysinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
Perturb_14685_KO_Lkb1_ERP006813	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.71777
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.872792
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cybrid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.346
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.123
PMC6290138__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
Liver Neoplasms	CTD Gene-Disease Associations	1.0	2.23968
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
MONOMAC1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.12309
PMC5612418__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42418
Scutellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Proteasome regulatory particle, base subcomplex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.153
KYSE520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56907
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPN	MSigDB Cancer Gene Co-expression Modules	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAMM50	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K68547601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56024
pole plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.225622
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12478
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12041
Methionine de novo and salvage pathway	WikiPathways Pathways 2024	1.0	null
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K00920341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65829
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.943
MFE-280	GDSC Cell Line Gene Expression Profiles	1.0	1.66914
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.28
sulfur amino acid catabolic process	GO Biological Process Annotations 2025	1.0	null
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
Perturb_11054_KO_Mettl3_SRP363782	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.22323
PMC7714782__F3	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07705
RBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06255
enzyme	GeneRIF Biological Term Annotations	1.0	null
BRD-K03286808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49466
MLYCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00064
PDX1_KO_GDS4348_360_mouse_Proximal small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
APP	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K20942146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2032
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
MAZ	ENCODE Transcription Factor Targets	1.0	null
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal liver morphology	MGI Mouse Phenotype Associations 2023	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.250568
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A70099008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03367
cellular amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01594
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906712
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61132
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MU-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RB1_KD_GSE50532_656_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K12111274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57145
due	GeneRIF Biological Term Annotations	1.0	null
linked	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7834
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67042
MAFF	ENCODE Transcription Factor Targets	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	2.07454
cell part	GO Cellular Component Annotations 2015	1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844531
mantle zone of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05825
PMC8851354-Table_5.xlsx-FUS-DDIT3_reg_FD-bound-Supplementary_Table_5_Genes_regulated_by_FUS-DDIT3_that_are_FUS-DDIT3_targets_in_MLS_402-91_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050468
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
abnormal liver size	MPO Gene-Phenotype Associations	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Maple syrup urine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
NDUFS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00574311
protein tetramerization	GO Biological Process Annotations 2025	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatitis	DisGeNET Gene-Disease Associations	1.0	null
Coelomic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
BRD-K78812892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49945
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13783
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859183
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
hyperhomocysteinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.462394
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42361742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27465
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9442
EP300_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A113-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADAMTSL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508095
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36516
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
BRD-K73637411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11064
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Phase II - Conjugation of compounds	Reactome Pathways 2024	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39566
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver And Intrahepatic Biliary Tract Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
FGF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17104
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19307
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.02971
ubiquitously	GeneRIF Biological Term Annotations	1.0	null
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852012
OVCAR5	CCLE Cell Line Gene CNV Profiles	1.0	1.42135
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.46821
BRD-K13637593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0226
MFE319_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	2.53974
GroEL-GroES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
Multiple synapse bouton, contacting multiple dendrites	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923335
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92781
C3A	CCLE Cell Line Gene Expression Profiles	1.0	3.40791
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Histidinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
mnng/hos	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
GSE246195,GSE246305_1_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LC4-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEBPA	MSigDB Cancer Gene Co-expression Modules	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
trastuzumab_homo sapiens_gpl570_gse15043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_TESTES_627_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intergeniculate leaflet	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64241
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.95978
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.38076
UMUC11	DepMap CRISPR Gene Dependency	1.0	3.5209
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83865
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZMYM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4868
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47792
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2118
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MOB3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18259
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965772
BRD-K23589316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58153
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49663
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Protein storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.523
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
novikoff hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.901573
variants	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7006-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33272704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48558
Perturb_15019_KO_Prdm3_SRP247808	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.59692
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06883
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.06504
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289938
Disease	Reactome Pathways 2024	1.0	null
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13677
Secondary cell wall cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
GTEX-TMMY-1226-SM-4DXT6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.86673
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.19
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.318911
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045794
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BSC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0439
PMC12549544-mmc2.xlsx-AA_D7_VS_D14-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.20978
PRC_Partial Depletion_GDS3531_563_human_U2OS cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19969
Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cholangiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.324
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K46120925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45797
Nuclear RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86029
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7259377__F6	PFOCR Pathway Figure Associations 2023	1.0	null
effects	GeneRIF Biological Term Annotations	1.0	null
neonatal	GeneRIF Biological Term Annotations	1.0	null
BRD-K75900642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63096
contributes	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4628-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35847
CTCF	ENCODE Transcription Factor Targets	1.0	null
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91821
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.506
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
BRD-K38932508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38335
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34696
BRD-K91885806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00211
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
NONO_02_149	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.85798
Feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.178
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.11749
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9146
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-WFON-0626-SM-4LVLX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53149
BRD-K28057105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84351
BRD-K33221810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90614
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Bile duct adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46348
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91241684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90243
Methionine adenosyltransferase deficiency, autosomal recessive	ClinVar Gene-Phenotype Associations	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06959
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.00404
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU1919_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	2.84625
FLCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1236
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
Perturb_10819_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.64189
USF1	ENCODE Transcription Factor Targets	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40382
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899078
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1826
S-adenosylmethionine biosynthetic process	GO Biological Process Annotations 2023	1.0	null
Cognition	HuGE Navigator Gene-Phenotype Associations	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3273
Lung squamous cell carcinoma_LUSC_TCGA-92-8065-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01912
Hyphal tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.915
NR2F2	ENCODE Transcription Factor Targets	1.0	null
BRD-K39237487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7205
CK syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
hsa-miR-3156-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-4700-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Perturb_10705_OE_ATF5/PROX1/CYP3A4_SRP287297	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.04094
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73166462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05384
baclofen_mus musculus_gpl1261_gse17266	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08766
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27866
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
upon	GeneRIF Biological Term Annotations	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6001
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095368
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.176
BRD-K40126748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43938
EP300_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.85
CRCGN014_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57566
MAPK14_KO_GDS2693_535_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
methionine metabolic process	GO Biological Process Annotations 2023	1.0	null
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.64937
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01143
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K03848296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95561
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2024	1.0	null
Ire1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.244
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0835
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52347
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.586
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17934
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67254
ESR1-17901129-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Spinal Dysraphism	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
Fumarate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
MOLM16_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.69162
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05723
HULC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
CRCGN013_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16067
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.83185
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16946
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.453
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14477_KO_Zfp36l2_SRP310261	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.9426
Hyperprolinemia type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
OVMIU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K06830450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19286
mesentery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.168501
10q22q23 copy number variation	WikiPathways Pathways 2024	1.0	null
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
improving	GeneRIF Biological Term Annotations	1.0	null
NCIH446	DepMap CRISPR Gene Dependency	1.0	3.12571
NSMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42418
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Megaloblastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.031303
BRD-K97588749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90805
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K94803981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00901
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO1	ChEA Transcription Factor Targets	1.0	null
BRD-K35122752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30327
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12982
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-A06578049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71055
Neoplasms	CTD Gene-Disease Associations	1.0	1.87725
Apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
BRD-K07525144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77771
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRELID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69741
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922546
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_11011_KO_Phpt1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.13556
hsa-miR-552	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC8482521-mmc10.xlsx-Upstreme_Regulators_48_hr_MLR-Unnamed_0_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79168
hsa-miR-4480	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52261
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99516
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58707
BRD-K10452371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29027
BRD-K75380271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01798
vitamin	GeneRIF Biological Term Annotations	1.0	null
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.281
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_CAMTA1_vs_subEV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12869
Flemming body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
PMC3174208__F1	PFOCR Pathway Figure Associations 2024	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
them	GeneRIF Biological Term Annotations	1.0	null
PMC11960529-mmc4.xlsx-Ventricular_ZNF711_KOoverCT-gene_ZNF711	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
BRD-K61287439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32166
Amino acid metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Alcoholic hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.889
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Commitment complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57572
CRCGN010_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50897
cc91	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088101
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74424
BRD-K67087027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12459
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74726
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23825243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24652
Rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hemolysis	CTD Gene-Disease Associations	1.0	1.12219
helicase	GeneRIF Biological Term Annotations	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.703536
ESR1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6463
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6743-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NAMALWA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54174
mRNA editing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.003
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Sensillum trichodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.379
ascites	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185236
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874738
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	5.13023
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Hepatoblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
PMC6826333__F1	PFOCR Pathway Figure Associations 2024	1.0	null
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02082
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1632
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38319
peripheral demyelination	HPO Gene-Disease Associations	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.45007
Methionine metabolism leading to sulfur amino acids and related disorders	WikiPathways Pathways 2024	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61124
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
appendices_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JNK_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00403
16699793-Table2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95908
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal peripheral myelination	HPO Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75452
phospholipid-translocating ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
nrk-49f cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33744
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853572
abnormal liver physiology	MPO Gene-Phenotype Associations	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043368
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02364
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.72999
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2786
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929589
MOLP8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68518
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33569
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tissue culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220152
Labellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
Chloroplast ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A 1120	DeepCoverMOA Drug Mechanisms of Action	1.0	0.54
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.93274
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91007
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
KNS-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61161
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
HT3	DepMap CRISPR Gene Dependency	1.0	2.54974
Trans sulfuration one carbon metabolism and related pathways	WikiPathways Pathways 2024	1.0	null
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.169636
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Larva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.589
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99242
KDM4C_natural variation_GSE41040_590_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17785
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.68454
UACC893	DepMap CRISPR Gene Dependency	1.0	2.58807
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04357
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18785
CRCGN013_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04481
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6228-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83682
BRD-K90519599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.169
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
L-Methionine	HMDB Metabolites of Enzymes	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79364
Hybridoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.205
endocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.928906
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81768
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-11A-12R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abscission zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8878
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.44181
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4286
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04021
cytosolic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.056925
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.601686
BRD-K09112411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43408
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03336
cation binding	GO Molecular Function Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61078510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35146
methionine metabolic process	GO Biological Process Annotations 2025	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K39227064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07078
ESR1_T47D_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
resulted	GeneRIF Biological Term Annotations	1.0	null
PMC6030166__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Vitamin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.713
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10303
BRD-K92749855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00633
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11232
nerve	GTEx Tissue Gene Expression Profiles	-1.0	-0.906243
BRD-K46334103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41471
PMC4239617__F10	PFOCR Pathway Figure Associations 2023	1.0	null
RPL23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64294
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2741
BRD-K21784579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23437
Anxiety Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
Short Stature	DisGeNET Gene-Disease Associations	1.0	null
BRD-K34595193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93687
NCIH716	Achilles Cell Line Gene Essentiality Profiles	1.0	1.14475
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
Tyrosinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3579
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Methionine adenosyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.977
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22656
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.45906
organonitrogen compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0705
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0134
CRCGN014_HEPG2_3H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56705
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05927
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
increased liver weight	MPO Gene-Phenotype Associations	1.0	null
tRNA methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.477
Liver Failure, Acute	CTD Gene-Disease Associations	1.0	1.38498
BRD-K91795767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05147
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15166
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
granule cell layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2622
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22035
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05485
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.087837
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.206
carboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K31883758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04664
BRD-K96839404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87948
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
larva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089571
mat	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86125
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	2.33055
wm115	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88616
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55584
PMC8410083-elife-65574-fig7-data1.xlsx-KLF10_network-Genes_bound_by_KLF10_in_their_-10_1kb_region_or_differentially_expressed_in_WT_vs_HepKO_hepatocytes_challenged_with_high_sugar_KLF10	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.095
Pneumonia	CTD Gene-Disease Associations	1.0	1.08975
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45851
Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.27
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81747
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63194
Prostate	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.828009
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.32918
BRD-K56691168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00521
core of nucleus accumbens	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.99294
eRF1 methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.711
BRD-K72278003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00038
BRD-K97391170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09234
liver_c	HPA Tissue Sample Gene Expression Profiles	1.0	2.11558
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.33464
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1714
RCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06661
COR-L88	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nucleobase-containing small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3926
PMC6471220__F3	PFOCR Pathway Figure Associations 2024	1.0	null
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043973
KMH2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09276
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glutamate formiminotransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
COPI vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.942
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35532
BRD-K59821372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53171
superficial stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07168
Novikoff hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
One Carbon Metabolism(Mus musculus)	WikiPathways Pathways 2014	1.0	null
BRD-K73582217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23803
anterior nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35581
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.048
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KASUMI1	DepMap CRISPR Gene Dependency	1.0	7.39142
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
homocystinuria-megaloblastic anemia cblG type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.937944
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26439
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-7774-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70090544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09035
exception	GeneRIF Biological Term Annotations	1.0	null
GSE145476_2_v_3_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.21431
PMC11236317-aging-16-205930-s001.pdf-1-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.194
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
HCT116	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.79429
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35221
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6045
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6740_KD_VPS4A/VPS4B_SRP187973	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.50006
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08579
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
USE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74597
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes Mellitus, Type 2	CTD Gene-Disease Associations	1.0	2.88009
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12551
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1106
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117764
gnmt	GeneRIF Biological Term Annotations	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22985
rc96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.169
Lung Diseases	CTD Gene-Disease Associations	1.0	1.28333
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Defective MAT1A causes MATD	Reactome Pathways 2024	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adventitious root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09341
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.08655
subcuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13152
Arteriosclerosis	CTD Gene-Disease Associations	1.0	1.20163
d17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
lm7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57747
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4h-LAS1L_KD_upreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
CEP290	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51673
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K36812047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41624
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97551
BRD-K27754030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81728
GSE193258,GSE193259_2_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-877	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99611
Selenoamino acid metabolism	Reactome Pathways 2024	1.0	null
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
PLEKHG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02576
Hepatic vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0014
plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316224
BRD-K00359952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.85093
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.782
NOMO1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.22517
report	GeneRIF Biological Term Annotations	1.0	null
BRD-K96845170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00639
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.39249
Dentate gyrus, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37384
Methylation	Reactome Pathways 2024	1.0	null
DCTN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00456802
Histidine metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.42229
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289226
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4G_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.35495
bile duct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340757
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872788
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
Heschl's gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.928189
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46043
PMC5300302__F7	PFOCR Pathway Figure Associations 2023	1.0	null
CRCGN014_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16064
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57094
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05495
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74329
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7453
CIAO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04757
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984371
BRD-K80577041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7434
Perturb_11277_KO_Bmal1_SRP060295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.1134
GSE199606_6_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31332
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1781
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
LS411N	Achilles Cell Line Gene Essentiality Profiles	1.0	1.06566
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84219
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052252
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45209
parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348889
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04778
metacyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.753297
One carbon metabolism and related pathways(Mus musculus)	WikiPathways Pathways 2014	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFE2L2_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.723739
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
phosphatase	Phosphosite Textmining Biological Term Annotations	1.0	null
liver	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	2.45842
methionine adenosyltransferase deficiency, autosomal recessive	OMIM Gene-Disease Associations	1.0	null
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.794
Metabolic dysfunction-associated steatohepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.031
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.38301
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9122
HNF4G	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00076
subunit	GeneRIF Biological Term Annotations	1.0	null
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6353
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.395709
dominant	GeneRIF Biological Term Annotations	1.0	null
MEC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6094
CRCGN015_HEPG2_48H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1503
purine ribonucleoside metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A181-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09023
PMC9376070-41419_2022_5157_MOESM15_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_of_CYTOR-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970755
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
BRD-K75551005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18016
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945097
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055718
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.03604
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51096
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7863452-12920_2021_883_MOESM2_ESM.xls-SRG_23_HCC_vs_17_NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9160962__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A20208638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54115
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S32W-0826-SM-4AD5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04438
s-adenosylmethionine biosynthetic process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46853
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
BRD-K13526564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34479
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34915
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SF172	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.25573
superficial stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31753
hsa-miR-29a	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08416
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12706077-44318_2025_598_MOESM21_ESM.xlsx-Dataset_EV19-hKidney_TPP-PISA-Genes_ZNF568	Rummagene Transcription Factor Associations 2026	1.0	null
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31508
T24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48927
depending	GeneRIF Biological Term Annotations	1.0	null
Pyrophosphate	HMDB Metabolites of Enzymes	1.0	null
Perturb_11023_KO_Rabl6_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.14135
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.487836
BRD-K83180232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70769
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hepatitis B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
Central vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.742
Jaw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.317
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K58843485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31633
UO31	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.47799
GTEX-PWN1-0726-SM-48TDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE149760_3_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cytosolic small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.229176
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10249
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08143
Perturb_10899_KD_Mdr2_SRP055450	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.55366
Plume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4187
ZEB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
indirectly	GeneRIF Biological Term Annotations	1.0	null
Middle frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	1.0	3.2651
Photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.664
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04335
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084146
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44095
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
CNPPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52577
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
mesocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.58322
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897099
BRD-K87159315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69662
HDAC1	ENCODE Transcription Factor Targets	1.0	null
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21472
CHD7	ENCODE Transcription Factor Targets	1.0	null
RH28	DepMap CRISPR Gene Dependency	1.0	3.01798
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.863865
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.29965
Chromosome Aberrations	CTD Gene-Disease Associations	1.0	1.0241
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72127
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832008
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94511
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859226
Wilson disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
developmental	GAD High Level Gene-Disease Associations	1.0	0.295739
hsa-miR-4665-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC7259377__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74258
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE212486,GSE212488_2_v_3_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hyperreflexia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K50216176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51547
intermediate stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06236
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839948
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15315
BRD-K58220038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63816
GSE199606_6_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OUMS23	DepMap CRISPR Gene Dependency	1.0	4.2319
liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0206
apoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.269335
PMC7039202__F3	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K24930745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18818
Perturb_1339_OE_MAT1A_SRP202083	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K08730943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29975
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16342
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24879
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7787
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831268
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.53334
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.946283
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75203
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.56676
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19988
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nuclear pore outer ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3312
alpha4-beta1 integrin-JAM2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.536
PMC6151027-12864_2018_5080_MOESM4_ESM.xlsx-Amino_Acid_Metabolism_50_AR-DEG-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.401572
Biliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.546
BRD-K89532826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1167
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.12
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248858_6_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKMEL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43479
BRD-K10541973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.8841
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
hsa-miR-4419a	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
CRCGN015_HEPG2_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.02837
2-amino-4-methylthio-3-butenoic acid	CTD Gene-Chemical Interactions	1.0	null
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32942
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50313
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86502
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04265
Phagophore assembly site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
PMC7863452-12920_2021_883_MOESM5_ESM.xls-SRG_13_GE2-HCC_vs_17NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37561
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48782
BRD-K49742819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70364
Translation initiation ternary complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.654
Protoxylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
BRD-K48195722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27844
Seta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.381
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25212
Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.90159
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870237
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.22692
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17544
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73616
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831059
Fibrosis	CTD Gene-Disease Associations	1.0	1.64348
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97527
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)	Reactome Pathways 2014	1.0	null
gata4_16914500_e9dot5_atrioventricular_canal_lof_mouse_gpl1261_gds3663	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.457655
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03629
ehrlich ascites carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.985425
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2452
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAOV3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.02467
cellular modified amino acid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-Embryo-Hatchling_1272_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
External female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
methionine adenosyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11895
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08863
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34872
liver	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25304254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06197
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
TOV21G	CCLE Cell Line Gene CNV Profiles	1.0	1.39531
BRD-K02204058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00716
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28499
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57353
highly	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A264-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE241701_2_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40271
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2393
Perturb_8385_KD_USP22_SRP213120	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.03091
non-alcoholic fatty liver	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
Host cellular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K90852412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11201
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.162
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
Prostomium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2648
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33452
r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13589
Height	DisGeNET Gene-Phenotype Associations	1.0	null
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95321
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BT474	CCLE Cell Line Gene Expression Profiles	1.0	1.50822
stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.329361
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18067
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23336
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Body wall muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.418
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-T_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.985787
Cleft Lip	HuGE Navigator Gene-Phenotype Associations	1.0	null
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40919
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09823
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84632
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831059
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37056
Thyroid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.429
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46567
translation	GeneRIF Biological Term Annotations	1.0	null
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
methylation	GeneRIF Biological Term Annotations	1.0	null
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.43374
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL2	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NAMALWA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50014
BRD-K40061713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25521
apical bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.521223
BRD-K68072222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03018
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01481
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inflorescence stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
Prepupa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.08868
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN235	DepMap CRISPR Gene Dependency	1.0	4.81683
BRD-K46239950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81496
Chloroplast thylakoid membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.802
HJURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30918
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
HCC1187	CCLE Cell Line Gene CNV Profiles	1.0	2.09872
none	GeneRIF Biological Term Annotations	1.0	null
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.46961
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.45045
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
Endocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
Seh1-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.18
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10702
hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.329565
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
methionine adenosyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14084
purine-containing compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
SNU719	CCLE Cell Line Gene Expression Profiles	1.0	1.60525
Liver Failure	CTD Gene-Disease Associations	1.0	1.17235
Kinesin I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K36134372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1743
BRD-K50300854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5414
BRD-K20624967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83806
posterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0827
lipid particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.169859
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14958
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079721
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054135
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Branch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9346
BRD-K93737936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3387
ZNF280A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15281
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K93195215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83082
HES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53646
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.782
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35871
BRD-K28601178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06223
Perturb_11132_OE_Cyp7a1_SRP066776	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.38
PATU8902	CCLE Cell Line Gene CNV Profiles	1.0	1.61952
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MELAS - Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes_Muscle - Striated (Skeletal) (MMHCC)_GSE1462	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.64594
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20869
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.82691
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04397
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_10828_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.80352
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1688	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Amino Acid Metabolism, Inborn Errors	CTD Gene-Disease Associations	1.0	2.88009
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03399
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78702
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89253
disease of metabolism	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-R55G-2426-SM-2TC5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
DNA Damage	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4977
BRD-K60057192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60041
CRCGN015_HEPG2_48H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54314
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898355
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55415
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69253
BRD-K70145120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16533
perianth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312232
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.04546
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73641
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3276
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13221
BRD-K38017028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15933
SW900	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K54053991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04068
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948592
GSE216538_0_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97362312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54085
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952489
Exocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
protein-kinase-c	Phosphosite Textmining Biological Term Annotations	1.0	null
cellular modified amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
intermediate stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55154
trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277197
BRD-K90697691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56224
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30615964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08039
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15397
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91773
coding	GeneRIF Biological Term Annotations	1.0	null
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.26947
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052006
xth2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.256
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44369
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K04562748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02741
Citrullinemia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38583
Perturb_11043_KO_Tmem97_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.31493
selenoamino acid metabolism	KEGG Pathways	1.0	null
HCC1187	COSMIC Cell Line Gene CNV Profiles	1.0	2.09073
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2463
CBX8	ENCODE Transcription Factor Targets	1.0	null
Acinar cell_Pancreatic islet_Human	CellMarker Gene-Cell Type Associations	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Hypodermal seam cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1891
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00832
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06287
Folate Metabolism(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.259
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
Siponimod	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
Liver-hepatocyte	Tabula Sapiens Gene-Cell Associations	1.0	7.8155
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPAP3/R2TP/prefoldin-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Metabolism	Reactome Pathways 2014	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.772
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88832
BRD-K38073091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23715
Glutamate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.307
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92118
BRD-K59535072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87063
3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.22
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
D-566MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54504
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Methionine Adenosyltransferase Deficiency	CTD Gene-Disease Associations	1.0	2.88009
aromatic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17244
SP in perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98959
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053651
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
MAT2A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K59772014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46723
BRD-K89932793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43133
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04923
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Lateral root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080733
upregulated	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6212
Seizures	CTD Gene-Disease Associations	1.0	1.15156
HEY	DepMap CRISPR Gene Dependency	1.0	3.07045
BRD-K71141540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02586
CAL120	CCLE Cell Line Gene CNV Profiles	1.0	1.5265
Perturb_10946_KO_Nr1d1_ERP117724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.6907
Inflammation	CTD Gene-Disease Associations	1.0	2.17489
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.55658
GTEX-XXEK-1426-SM-4BRW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K90951880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20929
Perturb_10985_KO_Fam210b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.74674
Amyotrophic lateral sclerosis type 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
risk	GeneRIF Biological Term Annotations	1.0	null
protein homotetramerization	GO Biological Process Annotations 2025	1.0	null
methionine-importing ABC transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.213
Hematuria	DisGeNET Gene-Phenotype Associations	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829096
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39099
lymph	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1605
CEBPA-23403033-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K83699731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37381
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2794-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NE-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein tetramerization	GO Biological Process Annotations 2023	1.0	null
CLDN18_KO_GSE48443_44_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37903
Perturb_11025_KO_Reg2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.19849
FOXA2	ENCODE Transcription Factor Targets	1.0	null
atp binding	GO Molecular Function Annotations 2015	1.0	null
lines	GeneRIF Biological Term Annotations	1.0	null
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41989
BRD-K79148949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51499
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2779
CYP2B6	MSigDB Cancer Gene Co-expression Modules	1.0	null
EFE184	DepMap CRISPR Gene Dependency	1.0	2.64804
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90833
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60272064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80934
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39636
BRD-K59250830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2923
autonomic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107194
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.642
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8293
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4888-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tafluprost	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57951
Perturb_11024_KO_Rbp4_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.17627
mantle zone of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03447
Female pudendum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848754
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.75371
C84	DepMap CRISPR Gene Dependency	1.0	2.17304
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2226-SM-2S1P1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.842
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
Nephritis, Interstitial	CTD Gene-Disease Associations	1.0	1.10631
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESR1-30970003-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K52492854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10384
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60989
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.658
PMC11659402-41523_2024_709_MOESM3_ESM.xlsx-Sheet2-ESR1_mutation_E2_Co-UP_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
NCOA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05768
BRD-K73831263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40981
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE155830_1_v_0_fkbp5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63299069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17283
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11987
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06364
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
alcoholism	GAD Gene-Disease Associations	1.0	null
GTEx Thyroid 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	6.96864
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49381
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3003
liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.432
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Metabolism	Reactome Pathways 2024	1.0	null
DNA replication factor C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
superpathway of methionine degradation	HumanCyc Pathways	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911773
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831059
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caused	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01493
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52001024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5673
BRD-K06264262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53222
Cvt vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.718
DMD_Deficiency_GDS2996_613_mouse_Cardiac muscles from 8-week (mdx animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18947
MON1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02615
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3176
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.116
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932236
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Perinuclear endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48791
CRCGN013_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.73378
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55738
targets	GeneRIF Biological Term Annotations	1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15389
Lung adenocarcinoma_LUAD_TCGA-05-4389-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92941354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12298
liminal part of the r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16676
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53726
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4026
GMNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13952
D423MG	DepMap CRISPR Gene Dependency	1.0	5.21745
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
BRD-K72647169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33796
BRD-K85741537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05004
abnormal liver physiology	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7804
Enhanceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
N-nitrosomorpholine	CTD Gene-Chemical Interactions	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869415
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metabolic	GeneRIF Biological Term Annotations	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.71317
BRD-K61139423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07961
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31854
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931316
6-phosphofructokinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5332
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25355
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Hyperhomocysteinemia	DisGeNET Gene-Disease Associations	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.21731
MVK	Pathway Commons Protein-Protein Interactions	1.0	null
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2052
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.054
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64007
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43449
ethanol_rattus norvegicus_gpl341_gse3311	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.56804
Bile duct cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K19089958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49469
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045015
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18962
TP63	ChEA Transcription Factor Targets	1.0	null
BRD-K76803075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24972
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4906
SRF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PDE10A_KO_GDS4542_292_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
BRD-K19536737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00794
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9211
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)	Reactome Pathways 2014	1.0	null
BRD-K75730049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02752
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.351002
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10436
BRD-K22718400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1738
plasma	GeneRIF Biological Term Annotations	1.0	null
determining	GeneRIF Biological Term Annotations	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K85776843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47327
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.725
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4031
SW13	GDSC Cell Line Gene Expression Profiles	1.0	2.12164
BRD-K75331656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37447
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1818
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20C-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859183
GSE198036,GSE198041_0_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78995236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00471
mat2b	GeneRIF Biological Term Annotations	1.0	null
BRD-K12003101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01367
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50522
OCIAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31183
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830179
inherited metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16935
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26057
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5089
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BORC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886969
Perturb_11048_KO_Ypel3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.34952
BRD-K68312794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09704
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4690-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
JHESOAD1	CCLE Cell Line Gene Expression Profiles	1.0	1.6719
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05441
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35711
BRD-K73539077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01378
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26385
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CAR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3174208__F1	PFOCR Pathway Figure Associations 2023	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976632
Chromoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.009
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
dimerization	Phosphosite Textmining Biological Term Annotations	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.09671
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1002
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
U118MG	DepMap CRISPR Gene Dependency	1.0	3.47933
BNIP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42733
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42542
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837836
BRD-K20831543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02513
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.478923
inheritance	GeneRIF Biological Term Annotations	1.0	null
LOX-1_OE_GDS4262_434_human_HAECT - aortic endothelial cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
dementia	GWASdb SNP-Disease Associations	1.0	0.345386
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919384
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3265
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260606
BRD-K22599787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00473
BRD-K59847773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20462
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
glutamyl-tRNA(Gln) amidotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
molecular layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01682
Viral hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
mode of inheritance	HPO Gene-Disease Associations	1.0	null
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06959
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.59966
hsa-miR-4722-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02178
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Methylation	Reactome Pathways 2014	1.0	null
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.349
HOP92	CCLE Cell Line Gene CNV Profiles	1.0	1.33356
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4448	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16147
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.879512
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
purine nucleoside metabolic process	GO Biological Process Annotations 2015	1.0	null
Nascent polypeptide-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.407
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93362
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU761	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60248
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.921298
S-adenosylmethionine synthetase, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.369
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059638
ESR1_T47D_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sulfur amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Water	HMDB Metabolites of Enzymes	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844442
Field CA3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45878
MYC	ENCODE Transcription Factor Targets	1.0	null
Orteronel	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32858
Perturb_11253_KO_Nampt_SRP133057	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.93
Memory	HuGE Navigator Gene-Phenotype Associations	1.0	null
cofactor biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849951
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107003
INA6	DepMap CRISPR Gene Dependency	1.0	2.51544
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13354
ITFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11896
BRD-K69699301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22237
CRCGN013_HEPG2_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01339
HNF4A	ChEA Transcription Factor Targets	1.0	null
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08826
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02038
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CCR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571308
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
INSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39571
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PEAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0507
ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K69291887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52191
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83538
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53515
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56169
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.644
Tassel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
HDA1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
BRD-A14484404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25249
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_11086_KO_Atf6_SRP332137	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.75314
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35772
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17035
PMC9609401__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K88890050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13244
BRD-A57594599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14702
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Childhood Hepatocellular Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
liverspecific	GeneRIF Biological Term Annotations	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Neural tube defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
RFX5	ENCODE Transcription Factor Targets	1.0	null
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)	Reactome Pathways 2014	1.0	null
BRD-K05357297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5498
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42939
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829039
sleeping sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.612401
CRCGN013_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10746
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
Root vascular cylinder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
Caov-3	GDSC Cell Line Gene Expression Profiles	1.0	1.60339
hsa-miR-873	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	1.0	2.69288
Dentate gyrus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47594
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11393
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1408
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29119
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Anaplastic thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.92771
sulfur compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10701
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88179337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85092
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.916858
Bile canaliculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
Spina bifida	WikiPathways Pathways 2024	1.0	null
PEBP1_KO_GSE31150_52_mouse_pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NB4	DepMap CRISPR Gene Dependency	1.0	2.39934
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1634
Hepatoma HLE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.544
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54295
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
xenobiotic metabolic process	GO Biological Process Annotations 2015	1.0	null
Cotton fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.021
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.293
Chemically-Induced Liver Toxicity	DisGeNET Gene-Disease Associations	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17189
Liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28473
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
Disease of metabolism	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
TAX1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9841
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1818
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Hypodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.643
Perturb_10992_KO_Il6ra_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.01601
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2384
Perturb_9806_KO_EBF4_SRP381947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.10407
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE62974_1_v_0_epas1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Biliary tract cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06054
liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.676706
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82037
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9561
BRD-K06091213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9427
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976632
Coelomocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
Perturb_8711_OE_SMAD4_SRP255626	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.90175
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2516
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3852
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18834
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34547
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16312305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44736
URM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3015
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colitis	DisGeNET Gene-Disease Associations	1.0	null
Perturb_11145_KO_1810027O10Rik_ERP013119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.51218
HNF1A-26855178-CACO2-HUMAN-COLON-ADENOCARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3233
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.864265
TCF7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66548
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74651
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.097203
S-adenosyl-L-methionine biosynthesis	HumanCyc Pathways	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A98099470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16051
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58086
Adult Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0112
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37087
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13424
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66181
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7628
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844969
hsa-miR-766	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.00707
pulp	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215051
Perturb_10818_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.99737
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
iiii	GeneRIF Biological Term Annotations	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01526
Myalgia	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-WEY5-1326-SM-3GILS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75391
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50073
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40365
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NCIH2347	CCLE Cell Line Gene Expression Profiles	1.0	1.35119
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.242
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	2.28489
BRD-K36804307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33897
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936479
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49663
BRD-K13849122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7367
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
Root apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
SW1783_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	13.2208
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910568
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41174
BRD-K09900382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07035
15980968-Table3b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_11323_KO_Bmal1_SRP153814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.07361
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840403
BRD-A23345137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81963
NOBOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501306
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4487
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
chr10_80286452_A_G_b38	GTEx eQTL 2025	1.0	4.12787
BRD-K49664555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18828
BRD-K85887470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81052
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-6.58307
methionine adenosyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.29673
Perturb_11316_KO_Noct_SRP120584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.2303
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.329837
Plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.642
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0179
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.39972
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01021
BRD-K95007662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1595
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
upregulation	GeneRIF Biological Term Annotations	1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00027
hsa-miR-3153	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	2.32071
estradiol_bos taurus_gpl2112_gse45857	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ8I-1326-SM-4BOPV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
hsa-miR-874	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
BRD-K71274071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92835
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26126
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0514
miR-142-3p_OE_GSE28456_470_human_Raji cells (B lymphocytes)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_11028_KO_Scarf2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.22756
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
ovary	HPA Tissue Gene Expression Profiles	1.0	0.89615
Septicemia	DisGeNET Gene-Disease Associations	1.0	null
review	GeneRIF Biological Term Annotations	1.0	null
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.92771
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fatty Liver	HuGE Navigator Gene-Phenotype Associations	1.0	null
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071974
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.557629
cofactor metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880688
S-Adenosylmethionine	CTD Gene-Chemical Interactions	1.0	null
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10T-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-588	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Final leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.050683
GSE217363_6_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28332
Lung adenocarcinoma_LUAD_TCGA-80-5611-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18077898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70888
mixed glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.605372
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
chr10_80285963_T_C_b38	GTEx eQTL 2025	1.0	6.71037
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1721
STK40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97402
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09341
L-540	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64352
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.45114
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Orbital area, ventrolateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06959
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
germ plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.230601
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315135
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37573
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
CEBPB	ChEA Transcription Factor Targets	1.0	null
Perturb_6761_KD_VPS4A/VPS4B_SRP187973	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.60366
Hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.04
MJ	CCLE Cell Line Gene Expression Profiles	1.0	1.40547
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03422
Kupffer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.313
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59094
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.48048
Etioplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
Nuclear dicing body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.535
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0487
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
fibrodysplasia ossificans progressiva	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.458996
frequency	GeneRIF Biological Term Annotations	1.0	null
BRD-K05222558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10173
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.25557
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07027
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918015
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
b21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
NCIH2171	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976632
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84068
Trans-sulfuration and one carbon metabolism(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
BRD-K18888894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72658
Filiform apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
pimasertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42411
BRD-K83697352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01514
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04486
neurological	GAD High Level Gene-Disease Associations	1.0	0.295739
Perturb_9831_KO_SIX6_SRP256351	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
hsa-miR-4725-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
One carbon metabolism	WikiPathways Pathways 2024	1.0	null
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.994091
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60228
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468048
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1932
PMC8528285-pbio.3001085.s010.xlsx-Fig_7G-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Peripheral Demyelination	DisGeNET Gene-Phenotype Associations	1.0	null
Hypermethioninemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.37
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
HEPG2	CCLE Cell Line Gene Expression Profiles	1.0	2.31132
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K93153656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64285
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00421
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42687
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3126-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
Glycogen granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.561
BRD-K97332312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54613
BRD-K24081812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72236
Food vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
TT2609C02	CCLE Cell Line Gene Expression Profiles	-1.0	-2.83624
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
GTEX-PWOO-2526-SM-2S1PG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
sulfur amino acid catabolic process	GO Biological Process Annotations 2023	1.0	null
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03643
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
Acute Myeloid Leukemia_LAML_TCGA-AB-2838-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TI-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65875972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15709
BRD-K70936779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.8798
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0188
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
pancreas	HPA Tissue Gene Expression Profiles	1.0	1.22638
Hepatic Methionine Adenosyltransferase Deficiency	DisGeNET Gene-Disease Associations	1.0	null
Perturb_11014_KO_Popdc3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.26502
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	2.88009
JNJ-38877605	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
BRD-K45185240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08163
BRD-K93601851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81109
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1107
GTEX-X8HC-0226-SM-4E3K1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35643
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.395
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68949590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10316
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34505
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	1.9413
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neurodevelopmental abnormality	HPO Gene-Disease Associations	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02074
BRD-K69109808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3219
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23733
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74097
Perturb_10860_KO_Med13_SRP302233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.1563
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.828
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71517
Hypospadias	CTD Gene-Disease Associations	1.0	1.01062
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06157545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96082
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53955
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61284
TAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79359
BRD-K16838444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87715
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8147
Shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00362
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7261
Biological oxidations	Reactome Pathways 2014	1.0	null
BRD-K18208847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60184
H1-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9724
CEBPA-23403033-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Perturb_10798_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.59189
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.355
ESR1	ChEA Transcription Factor Targets	1.0	null
One carbon pool by folate	KEGG Pathways 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R2-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MIF_DEPLETION_GDS3626_95_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN013_HEPG2_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28869
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
kidney hypertrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.506507
hepatoma	GeneRIF Biological Term Annotations	1.0	null
Vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.823
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Methylmalonic acidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.729
Prostatic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Cystathionase Deficiency	DisGeNET Gene-Disease Associations	1.0	null
Liver reticuloendothelial system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.309
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052527
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67078
BRD-K45348630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35904
SKNMC	DepMap CRISPR Gene Dependency	1.0	7.57284
Metabolism of amino acids and derivatives	Reactome Pathways 2024	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20113
BRD-K20271299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89394
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9666
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270909
cn96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.03855
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.58605
MCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46929
BRD-K68008192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18906
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15138_KO_Nlk_SRP259678	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Pericarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Cortical microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
Biliary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
BRD-K67027685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46628
Perturb_10829_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.82855
hepatic steatosis	MPO Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66425065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1233
BRD-K64180195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07576
Sternum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
abnormality of carboxylic acid metabolism	HPO Gene-Disease Associations	1.0	null
hsa-miR-3175	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.644
Dimethyl Sulfoxide	CTD Gene-Chemical Interactions	1.0	null
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872843
S-adenosylmethionine metabolic process	GO Biological Process Annotations 2025	1.0	null
chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.288514
BRD-K26351062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5645
Alcoholic liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
PMC10079833-41467_2023_37542_MOESM11_ESM.xlsx-Sheet1-Supplementary_Data_10_Significantly_differentially_expressed_genes_identified_in_IGF2BP1-KD_cells_compared_to_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Albedo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.788733
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.228
ZNF143	ENCODE Transcription Factor Targets	1.0	null
PELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62367
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040464
GSE218781_3_v_1_abl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06968
Defective UGT1A1 causes hyperbilirubinemia	Reactome Pathways 2014	1.0	null
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27739
BRD-A97759891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04622
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94052
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.512
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.33846
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.042996
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	0.830433
Diabetic Nephropathy_Renal Tissue_GSE1009	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.405733
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EW8	CCLE Cell Line Gene Expression Profiles	1.0	1.41134
posttranscriptional	GeneRIF Biological Term Annotations	1.0	null
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17629
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26837
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
homocysteine	GeneRIF Biological Term Annotations	1.0	null
MELHO	CCLE Cell Line Gene Expression Profiles	1.0	1.90395
3-methylcrotonyl-CoA carboxylase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.763
ERBB2_knockdown_235_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.73009
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3501
FGFR2_activemutant_59_GSE17916	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.87743
ZNF384_02_203	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64386
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Very long chain acyl-CoA dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2382
BRD-K38370827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30042
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1004
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
BRD-K73562260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46321
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Glycolate oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4484	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SW620	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.956443
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.990679
nucleoside biosynthetic process	GO Biological Process Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51844
PMC10338540-41416_2023_2282_MOESM2_ESM.xlsx-AA_metabolism-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	0.939189
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393064
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
liminal part of the r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06749
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_11005_KO_Nudt14_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.31071
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4924
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956779
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.13
TRIM28	ENCODE Transcription Factor Targets	1.0	null
Chloroplast ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.666
BRD-K76426411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20397
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911762
Phase II conjugation	Reactome Pathways 2014	1.0	null
Galactosemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.7031
Pith	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
BRD-K23220745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36238
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
HCT116_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.4896
BRD-K93785828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47421
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.844
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5989
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69113
Endoplasmic reticulum palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
STARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11811
GSE111247_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEPG2	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.446
BRD-K81952048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49779
GSE243491_1_v_2_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09857
methionine	GeneRIF Biological Term Annotations	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.6043
BRD-K23963854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23939
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.058982
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.9795
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALPL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00504976
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32481
Anterior group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47751
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27828
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859325
Methionine adenosyltransferase deficiency, autosomal dominant	ClinVar Gene-Phenotype Associations	1.0	null
mir495	GeneRIF Biological Term Annotations	1.0	null
ENSG00000230707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36834
tRNA (m2G10) methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.716
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879519
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64305
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11911
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21878
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gican	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
cleft lip; cleft palate	GAD Gene-Disease Associations	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K08416880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2063
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anemia, Hemolytic	CTD Gene-Disease Associations	1.0	1.26917
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)	Reactome Pathways 2014	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.04559
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.18259
Internode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.355
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01764
subset	GeneRIF Biological Term Annotations	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Halitosis	DisGeNET Gene-Phenotype Associations	1.0	null
HT-1080	GDSC Cell Line Gene Expression Profiles	1.0	1.4838
Flag leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.091
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07168
acetyl-coa carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.509604
Lung adenocarcinoma_LUAD_TCGA-75-6205-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:M18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86971
hsa-miR-4649-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974712
plant-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.572
ATP6V1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07875
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8128
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952178
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.574385
root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166167
skmel30	HPA Cell Line Gene Expression Profiles	1.0	0.886529
pkc	Phosphosite Textmining Biological Term Annotations	1.0	null
mantle zone of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06699
OCIM1	CCLE Cell Line Gene Expression Profiles	1.0	1.45787
Isovaleric acidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.797
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51096
Perturb_11031_KO_Slc45a3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.31757
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hur	GeneRIF Biological Term Annotations	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4848
rat	Phosphosite Textmining Biological Term Annotations	1.0	null
SBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20032
SNU1105	DepMap CRISPR Gene Dependency	1.0	2.45633
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15746
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901395
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
BRD-K42480393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27705
Kidney Tubular Necrosis, Acute	CTD Gene-Disease Associations	1.0	1.19146
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hcc	GeneRIF Biological Term Annotations	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13402
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38514
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9499
Akd	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84815485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27928
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
hep-g2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11553
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
adult-onset type II citrullinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.994
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
BRD-K60521891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55475
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.288
Perturb_7031_KD_Casz1_SRP038989	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.73277
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.966281
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_11220_KO_Cga_SRP405950	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.69095
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933494
PMC6030166__F6	PFOCR Pathway Figure Associations 2023	1.0	null
prethalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15616
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7368
Adenosine triphosphate	HMDB Metabolites of Enzymes	1.0	null
an3ca	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
ZNF217	ENCODE Transcription Factor Targets	1.0	null
hypertension	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076234
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70217
HS746T	DepMap CRISPR Gene Dependency	1.0	4.50883
BRD-K78658063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62613
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Teratoma	DisGeNET Gene-Disease Associations	1.0	null
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0356
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37025
abnormal myelination	HPO Gene-Disease Associations	1.0	null
C3A	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.02408
binding	GO Molecular Function Annotations 2015	1.0	null
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.489171
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
Storage root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K54922310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34492
Sumatriptan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066488
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4901
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05591
TBP	ENCODE Transcription Factor Targets	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988224
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34822
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Organic acidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3986
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836708
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51815
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.169094
BRD-K22316029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43546
KALS1	DepMap CRISPR Gene Dependency	1.0	2.39663
E2F6	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Mantle muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
methylation	GO Biological Process Annotations 2015	1.0	null
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58838
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.047849
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54188
COLO-678	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Plant cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2617
BRD-K04725393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	2.65595
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.4211
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19C-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW8	DepMap CRISPR Gene Dependency	1.0	7.37528
19377508-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K93032100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54617
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11074_KO_Prkcb_SRP330448	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.33476
assayed	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
galician	GeneRIF Biological Term Annotations	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K22447639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32486
hsa-miR-3679-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_8043_KO_Zeb2_SRP261907	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.6371
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59356
HPX	MSigDB Cancer Gene Co-expression Modules	1.0	null
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13177
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.995425
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33975
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12044
ACTMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01623
Magnesium	HMDB Metabolites of Enzymes	1.0	null
BRD-A21877498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0071
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
recessive	GeneRIF Biological Term Annotations	1.0	null
most	GeneRIF Biological Term Annotations	1.0	null
PMC5300302__F7	PFOCR Pathway Figure Associations 2024	1.0	null
Hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.006
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.34918
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.42395
POR_KO_GDS1678_763_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.74301
abnormal liver weight	MPO Gene-Phenotype Associations	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.36128
BRD-K18686200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06487
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.3412
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SK-MEL-5	GDSC Cell Line Gene Expression Profiles	1.0	1.78049
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963662
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial (main) part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33134
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47791
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5956
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BMY 7378	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90225
MEND syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1818
enlarged liver	MPO Gene-Phenotype Associations	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06655
ESR1_T47D_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14211116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38299
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348889
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-A73150064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23512
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18748
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04578
EFM19	DepMap CRISPR Gene Dependency	1.0	2.08133
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00804
GTEX-SSA3-0426-SM-32QPI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K28952606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36617
ADHD and autism ASD pathways	WikiPathways Pathways 2024	1.0	null
hilus of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54809
BRD-K69521416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3063
Barrett Esophagus_Esophageal Tissue_GSE1420	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.78871
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078391
SNX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49139
rather	GeneRIF Biological Term Annotations	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22885
CRCGN013_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.56267
Radiation Injuries	HuGE Navigator Gene-Phenotype Associations	1.0	null
Stoma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
SPI1	ChEA Transcription Factor Targets	1.0	null
ITGB1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04646
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5251
liver	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.865884
Pregnancy Complications	CTD Gene-Disease Associations	1.0	1.01776
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
Invertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.342
dystonia	HPO Gene-Disease Associations	1.0	null
ls1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221521
ribonucleoside biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Methylation Pathways(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
CMAH_KO_GDS4200_114_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.098
RPS19BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08688
hsa-miR-3188	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Hepatoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
HO-1-U-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.09073
One Carbon Metabolism(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
OCIAML3	Achilles Cell Line Gene Essentiality Profiles	1.0	2.25069
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
hep-3b cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.646911
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6024
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.991909
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7186
GTEX-WFG7-1226-SM-4LMK2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.13381
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34895
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00617
Hypertension	CTD Gene-Disease Associations	1.0	1.32756
Middle lamella	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
CDC25C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00544701
Lung squamous cell carcinoma_LUSC_TCGA-21-5786-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
Icotinib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.42
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immune system phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855096
SRF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE-296	GDSC Cell Line Gene Expression Profiles	1.0	1.65708
everolimus_mus musculus_gpl6885_gse37129	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Glycine cleavage complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.332
Poisoning	CTD Gene-Disease Associations	1.0	1.6428
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6998
FAM118A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07439
GSE171269_1_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hepatoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
SRF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-485-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CRCGN015_MCF10A.TP53.M_24H:A05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05881
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-2.64338
ratio	GeneRIF Biological Term Annotations	1.0	null
Feather vane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.328
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12902
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28146
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.06383
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900503
OVK18	CCLE Cell Line Gene Expression Profiles	1.0	1.76594
hsa-miR-664	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Short chain acyl-CoA dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.881
Cvt vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.308
CAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02668
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8707
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081889
Polyps	DisGeNET Gene-Phenotype Associations	1.0	null
PMC5612430__F1	PFOCR Pathway Figure Associations 2023	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.93426
PLC-PRF-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.59606
regulated	GeneRIF Biological Term Annotations	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.536
DUSP1_KO_GDS1606_773_mouse_spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
duodenal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.522273
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09259
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26373865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09497
SETDB1	ENCODE Transcription Factor Targets	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2897
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_817_KO_BCL7A/BCL7B/BCL7C_SRP345839	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49142
L2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43993
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8954
Perturb_10977_KO_Dnase1l2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.99298
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.23296
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
UACC257	DepMap CRISPR Gene Dependency	1.0	2.08847
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.71208
therapy	GeneRIF Biological Term Annotations	1.0	null
Edema	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
severe	GeneRIF Biological Term Annotations	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42814
PMC9068765-41467_2022_29960_MOESM14_ESM.xlsx-TP53-Unnamed_2_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15678
BRD-K38358574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10091
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831059
BRD-K61439332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25413
BRD-K92520489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93253
PMC12800118-41698_2025_1217_MOESM1_ESM.pdf-6-JDP2_JDP2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75595810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.894
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061565
Adventitious root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.6
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.83808
BRD-K43680691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18528
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.471539
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.60795
Sulfur amino acid metabolism	Reactome Pathways 2024	1.0	null
BRD-K65829768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39262
Vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.797
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Tuber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
PMC6290138__F2	PFOCR Pathway Figure Associations 2023	1.0	null
promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.45374
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.67202
Vitamin B12 Metabolism(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
FZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42199
8-MG-BA	GDSC Cell Line Gene Expression Profiles	1.0	1.58155
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08294
A101D_SKIN	CCLE Cell Line Proteomics	1.0	2.026
Vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.673
BRD-K23905877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33119
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8409
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8236
protein homooligomerization	GO Biological Process Annotations 2025	1.0	null
hsa-miR-4300	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
BRD-K18117162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44382
SKMEL5	CCLE Cell Line Gene Expression Profiles	1.0	1.98452
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04011
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7974
Ventral part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79475
Hepatic Encephalopathy	CTD Gene-Disease Associations	1.0	1.30911
GTEX-XUW1-1126-SM-4BONZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19911
Ozagrel	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
BRD-K47995281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33916
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21146
S-Adenosylmethionine	MW Enzyme Metabolite Associations	1.0	null
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32403
Perturb_10711_KO_Nrf2_SRP336215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.14942
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.66317
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.03567
immobilized cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.533856
CYCLIN_D1_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Breast Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
nucleotide-excision repair factor 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.01
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850219
ESYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45123
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Demyelinating Diseases	CTD Gene-Disease Associations	1.0	2.88009
Perturb_8065_KD_GFER_SRP239459	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.50561
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14564
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03362
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.46736
BRD-K10847374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06665
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1	ENCODE Transcription Factor Targets	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10563
abnormality of aspartate family amino acid metabolism	HPO Gene-Disease Associations	1.0	null
BRD-K19492738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2674
GTEX-WY7C-0926-SM-3NB34	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62282
one-carbon metabolic process	GO Biological Process Annotations 2015	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
OCIMY5	DepMap CRISPR Gene Dependency	1.0	2.08379
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
six	GeneRIF Biological Term Annotations	1.0	null
ACLY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00504827
oseltamivir-phosphate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.564
Fine root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
Glutamate synthase complex (NADPH)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.287
NR1I2	ChEA Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842038
xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.409351
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YJ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99413603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57369
Ocellus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.231206
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4740-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
synostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.425139
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.19247
S-adenosylmethionine biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
lateral part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05723
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40785
Fatty Liver	CTD Gene-Disease Associations	1.0	2.88009
increased circulating methionine level	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K65265098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6955
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618978
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36944891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39961
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.018
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.25713
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.033032
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.766
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
macrovesicular hepatic steatosis	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K07351191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88237
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10805
vascular disease	GWASdb SNP-Disease Associations	1.0	0.069172
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	0.851075
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Pneumocystis Jiroveci Pneumonia	DisGeNET Gene-Disease Associations	1.0	null
taiwanese	GeneRIF Biological Term Annotations	1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11
BRD-K35520972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56345
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
Hak	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
isolated	GeneRIF Biological Term Annotations	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4664-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45475
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
abnormal peripheral nervous system morphology	HPO Gene-Disease Associations	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5799
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08056
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K58696904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66205
GSE145476_1_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160017,GSE160022_1_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87634
GTEX-P4PP-1726-SM-2S1NS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.531
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PPARA_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_4_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bile duct carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Finasteride	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Liver Diseases	CTD Gene-Disease Associations	1.0	1.96847
Adult Hepatocellular Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.35189
corolla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340388
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
tumorigenesis	GeneRIF Biological Term Annotations	1.0	null
BRD-K86155080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41193
Gut granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
MYBL2	ENCODE Transcription Factor Targets	1.0	null
Perturb_8324_KD_INO80_SRP103083	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.93044
Cellulose microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.934
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
SP3_Deficiency_GDS3058_610_mouse_Embryonic heart  (day 12.5 C57Bl/6)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rat-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303198
IFT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2951
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31577
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hyperprolinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
purine ribonucleoside biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Vitamin B12 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
Diabetic kidney disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.604576
Peroxisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.777
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Chloroplast thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.835
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32327
BRD-K63624341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42398
GSE237040_0_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.627
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
serine-pyruvate aminotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.314
LAMA2_Deficiency_GDS1778_747_mouse_Diaphragm (from dystrophia muscularis -dy/dy- mouse model)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE148658_1_v_0_six6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A59683007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10936
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_10800_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.39815
BRD-K15282144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37085
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CCLFUPGI0005T	DepMap CRISPR Gene Dependency	1.0	10.8652
GSE246983_1_v_0_cdk12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tyrosinemia type III	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06775
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42126874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4425
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8043
Geniculate group, ventral thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68167
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42179
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49676
BRD-K57184082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04362
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08122
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.06618
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21455
Eplerenone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
disease	GWASdb SNP-Disease Associations	1.0	0.026832
S-Adenosylmethionine	HMDB Metabolites of Enzymes	1.0	null
petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.363393
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8333
PMC5612418__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.05019
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052262
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32182
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FTC-133	GDSC Cell Line Gene Expression Profiles	-1.0	-1.79626
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64662
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
increased liver weight	MGI Mouse Phenotype Associations 2023	1.0	null
Bacterial degradosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
IL17RC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39913
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
COLO783	CCLE Cell Line Gene Expression Profiles	1.0	1.85169
BRD-K90429860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11788
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.981169
BRD-K95479169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24687
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45921
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920295
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11184_KO_Jmjd1c_SRP239229	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.65686
Perturb_8395_KD_Atoh8_SRP410862	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.96184
BRD-K11242872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88063
Perturb_10736_OE_Nampt_ERP132005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43534
BRD-K74677971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88607
Methionine adenosyltransferase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CALU6	DepMap CRISPR Gene Dependency	1.0	3.80376
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_10846_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.09956
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
troglitazone_rattus norvegicus_gpl341_liver_gds3850	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TSHZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19617
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.322
SNU5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.3147
mantle zone of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16571
Acetaminophen	CTD Gene-Chemical Interactions	1.0	null
BRD-K08929846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05262
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.108937
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of body height	GWASdb SNP-Phenotype Associations	1.0	1.04992
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47392
PC-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.40381
BRD-K95935249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27052
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Chemical And Drug Induced Liver Injury	DisGeNET Gene-Disease Associations	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30359
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Childhood Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K96807219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12948
ARID3A	ENCODE Transcription Factor Targets	1.0	null
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
alitretinoin_rattus norvegicus_gpl85_liver   b_gds2385	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K78315404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76294
Hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.325
Phosphoric acid	HMDB Metabolites of Enzymes	1.0	null
abnormal cns myelination	HPO Gene-Disease Associations	1.0	null
PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43777
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	1.0	2.90909
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Hyperplasia	DisGeNET Gene-Phenotype Associations	1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53185
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
alar plate of p3 (alar prethalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15729
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_8423_KO_DGAT2_ERP114849	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
tauopathy	GWASdb SNP-Disease Associations	1.0	0.574385
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09982
Hypertension	HuGE Navigator Gene-Phenotype Associations	1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14084
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6589
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
3-Oxiran-2ylalanine	DrugBank Drug Targets	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Personality Tests	HuGE Navigator Gene-Phenotype Associations	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0021
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289226
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Essential Thrombocytemia_Thrombocyte_GSE2006	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.63059
angiogenin-PRI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.752
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.673917
Hamartoma	DisGeNET Gene-Disease Associations	1.0	null
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC7A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77075
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.728389
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Pulvinus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6048
carbohydrate derivative metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC6442705__F7	PFOCR Pathway Figure Associations 2024	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Stipe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.093
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04296
BRD-K30682979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94242
Multiple carboxylase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
BRD-K89811208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05626
hypermethioninemia	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Cleft Palate	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE193351_1_v_9_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.139
deficiency	GeneRIF Biological Term Annotations	1.0	null
PRKCA_KO_GDS2141_300_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNU-61	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LYRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92673
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Lipid droplet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.706
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.43576
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20422
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isoenzyme	GeneRIF Biological Term Annotations	1.0	null
GATOR1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
A427	GDSC Cell Line Gene Expression Profiles	1.0	1.72157
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.587
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCAR2_02_146	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65208
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OAW42	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.01275
KP2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.42689
Phenylketonuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42293
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Macrocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
GSE237040_4_v_3_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53552
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896424
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44264
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
Alcoholism	HuGE Navigator Gene-Phenotype Associations	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.25
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-HEP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
BRD-K84199148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26243
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.039875
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dystonia	DisGeNET Gene-Phenotype Associations	1.0	null
cls1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.913
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
meta1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Phagophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.11
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.34529
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15253
BRD-K75413392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02415
CTSA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555221
Vascular cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
FOXM1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240896,GSE240899_2_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05151
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
Ornithine carbamoyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU840	CCLE Cell Line Gene Expression Profiles	-1.0	-3.25871
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51096
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6231
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Central Nervous System Demyelination	DisGeNET Gene-Disease Associations	1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
hypermethioninemia	GeneRIF Biological Term Annotations	1.0	null
Perturb_11146_KO_3110043O21Rik_ERP013119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.85305
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.875
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.837604
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
PMC12062214-41467_2025_59646_MOESM5_ESM.xlsx-HMGA2_activated_repressed-Gene_symbol_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53141
transcription	GeneRIF Biological Term Annotations	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3226
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
Biotinidase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.082363
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF767	CCLE Cell Line Gene CNV Profiles	1.0	2.47098
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.95802
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSF1_KD_GDS1733_750_human_HeLa cells - 0 Hour	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PKBalpha_KO_GDS1784_197_mouse_Embryonic fibroblasts (MEFs) - 48h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11552
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE167984,GSE167987_0_v_1_setd1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
a24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47397
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
BRD-K41307363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21286
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32943
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10341
Choline deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12779
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.839757
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Cob	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
MCAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
genetically	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFJO-1926-SM-3GILA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4857-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bud8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.354
BRD-K32037893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8344
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
very-low-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.863
EP300_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Catalytic step 1 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95974
PMC9950457-mmc3.xlsx-GRHL2_overexpression_DOWN-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC70	DepMap CRISPR Gene Dependency	1.0	6.13514
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47966
Sapling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
LCAT	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K29083370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04904
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K88070373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38168
NCI-H1355	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plhc-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315498
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846602
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_ATF5-Logfold_change_threshold_1_0_1_ATF5	Rummagene Transcription Factor Associations 2026	1.0	null
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2706
BRD-A47963183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89853
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48596
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4068
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11861
BRD-K57343972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62553
Dbf4-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88601
BRD-K48207398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32371
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K18070214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17633
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.752785
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079614
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.844873
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976908
BRD-K41089262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4886
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
Glycoprotein network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.945
BT20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9616
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84219
KMS12BM	Achilles Cell Line Gene Essentiality Profiles	1.0	2.03817
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899746
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29729
PMC6169732-NIHMS77178-supplement-Table_S3.xlsx-Genes_repressed_by_TRPS1-GeneSymbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.12242
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87558616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33927
NDUFA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15221
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856242
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14016
BRD-K47572485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36226
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27739
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838446
Hepatic stellate cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.466
CREBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1706
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70144
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.833223
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.27
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ACT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.562
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1312
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292436
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Plant candle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_RORC-Logfold_change_threshold_1_0_1_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17404
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9237
intermediate stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23924
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0849
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K78397696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53032
GSE240896,GSE240899_2_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cholangiocarcinoma	CTD Gene-Disease Associations	1.0	1.07804
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Sporulating cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.581
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Vitamin B12 metabolism	WikiPathways Pathways 2024	1.0	null
BRD-K04848570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94906
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5694
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16561
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49253
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
hsa-miR-4438	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Kidney Chromophobe_KICH_TCGA-KM-8441-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3622b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65098
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061178
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
BRD-K70148902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85609
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.46961
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	3.94532
GSE205540_2_v_1_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48305
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Bile duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
abnormal pyramidal signs	HPO Gene-Disease Associations	1.0	null
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.19295
Plasmodesma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.544
Metacyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
PMC5571732__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Mesophyll	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37436
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
superior mesenteric artery syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.31013
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0458
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04372
NB10	DepMap CRISPR Gene Dependency	1.0	2.35591
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of sulfur amino acid metabolism	HPO Gene-Disease Associations	1.0	null
GSE207914_1_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.8238
Perturb_4393_KD_EHMT2_SRP290196	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
peritoneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.140232
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954562
Lung squamous cell carcinoma_LUSC_TCGA-33-4582-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55596
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.951
homocystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.54098
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
abnormal hepatobiliary system physiology	MPO Gene-Phenotype Associations	1.0	null
BRD-K47087435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59704
RBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77517
variant	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26976202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41264
ANKRD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57371
Hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901916
Perturb_11004_KO_Nhlh2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.22339
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06558
EIF2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74606
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15527
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04934
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3037
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51272
GSE193993_5_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06287
CRCGN017_MCF10A.TP53.M_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15955
BRD-K55800245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00559
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
S-adenosylmethionine synthetase, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
Symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
FAM171A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01485
NCIH524	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66998
BRD-K76600600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3156
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25821
ME-180	COSMIC Cell Line Gene CNV Profiles	1.0	2.09073
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0981
TP53INP2_KO_GDS5053_544_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06426
BRD-K43982279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55466
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962098
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11758
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46648
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38898
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-1726-SM-33HB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.64069
ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.081912
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00011
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K82883803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08877
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.996295
CRCGN017_MCF10A.WT.HP_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0164
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416576
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33523
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.308
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53185
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56302
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830179
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alkaptonuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
BRD-K53665750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20029
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12451
amino acid metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977911
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Thalamus, polymodal association cortex related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27739
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61303
BRD-K33462260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43437
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11144_KO_Klf14_ERP010756	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.83658
sulfur compound biosynthetic process	GO Biological Process Annotations 2023	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
alphaIIb-beta3 integrin-talin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.821
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15844
BRD-K38084509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08598
20592013-Table2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K28803288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06962
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.29641
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14284
Hyperhomocysteinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.0
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2094
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.63756
Glyoxysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.903
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Defective GGT1 causes Glutathionuria (GLUTH)	Reactome Pathways 2014	1.0	null
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
P30-OHK	GDSC Cell Line Gene Expression Profiles	-1.0	-1.70039
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13263
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922546
SubthalamicNucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.49891
BRD-K43205312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18884
BRD-K41382866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35456
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
hsa-miR-3622a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16943
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
VRK1_knockout_64_GSE19329	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.1791
Cytochrome b6f complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
single-organism process	GO Biological Process Annotations 2015	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.892948
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.23601
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
ATM_Deficiency_GDS1544_769_mouse_Lymph nodes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.49613
Atg12-Atg5-Atg16 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.717
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066773
Weight Gain	CTD Gene-Disease Associations	1.0	1.70802
CUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70677
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.804772
Kidney Chromophobe_KICH_TCGA-KN-8437-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950106
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
whose	GeneRIF Biological Term Annotations	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HOP62	DepMap CRISPR Gene Dependency	1.0	2.05903
EP300_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MICAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75518
Glutaric acidemia I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
GTEX-S4Z8-2026-SM-3K2A9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268137
PMC5131312-srep38063-s2.xls-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71204
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8268
epicotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05149
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
EP300_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
impairment	GeneRIF Biological Term Annotations	1.0	null
purine-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5758
Vegetative stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31462
Callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
Perturb_11027_KO_Rilp_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.01587
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26275
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09669
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
included	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85051145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04414
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.014
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrion-derived vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23804
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CYCLIN_D1_KE_.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	1.0	1.18865
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48923
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11861
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1632
ZNF180_02_177	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58981
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998897
SF767	DepMap CRISPR Gene Dependency	1.0	2.54898
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.21501
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347038
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53991
Perturb_11021_KO_Pxdc1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.86867
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
BRD-K01554997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24244
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2157	COSMIC Cell Line Gene CNV Profiles	1.0	2.09073
VMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21169
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03641
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.4888
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07755
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892679
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90273
hypermethioninemia	HPO Gene-Disease Associations	1.0	null
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02074
MET_knockout_258_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.859732
splicing	GeneRIF Biological Term Annotations	1.0	null
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884162
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24464
BRD-K72261386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48984
Secondary progressive multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09778
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
S-Adenosylhomocysteine Hydrolase Deficiency	DisGeNET Gene-Disease Associations	1.0	null
BRD-K85615919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31637
Perturb_10950_KO_31O21Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.48282
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094807
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1818
BRD-K22944782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05754
Cancer of thyroid_Thyroid_GSE5364	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.69108
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03922
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52441396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58486
GSE228125_0_v_3_ptafr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19911
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TFE3_vs_EV-Gene_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17549
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12469242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13034
18786252-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-NFK9-1226-SM-3LK79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
single-organism biosynthetic process	GO Biological Process Annotations 2015	1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873467
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0581
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55431
RING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68569
N-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)	Reactome Pathways 2014	1.0	null
pregeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4839
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99774
shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.7619
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18882
Autophagosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
Homocystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.757
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20889
rko cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33413
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Photosystem II reaction center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
hepatocellular	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0502
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13425
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nucleobase-containing compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
BRD-K44133102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87728
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27972
biliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.265725
BRD-K26314798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26618
small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.114318
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88613983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82737
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05267
intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.202346
aleurone layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436055
BRD-A44438286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22368
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4433
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46043
BRD-K94088690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00281
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
NAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22726
Vacuolar proton-transporting V-type ATPase, V1 domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.973
MRPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88123
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Serine C-palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
BRD-K11227160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22996
BRD-K75821161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30817
Apoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.659
GSE240896,GSE240899_10_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K99022424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07467
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MS-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19998
BRD-K78245984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30609
PMC11711664-41598_2025_85366_MOESM6_ESM.xlsx-AA-METABOLIC_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RT11284	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74033
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21644
GATA2	ChEA Transcription Factor Targets	1.0	null
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44873
BRD-K40116023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56298
cancer stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.197998
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.17662
Asthma, allergic_Bronchial epithelium_GSE3004	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.3956
BRD-K88934376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36273
Pharyngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
SCC90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K04371719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2111
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
activities	GeneRIF Biological Term Annotations	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital Absence Of Liver	DisGeNET Gene-Disease Associations	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.233
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51004
CRCGN012_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44178
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58807
ProVWX complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1588
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16783
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4836
cell septum	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.6638
NCIH322	DepMap CRISPR Gene Dependency	1.0	3.92071
BRD-K37830990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03693
purine nucleoside biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1363
BRD-K50129495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16797
protein homotetramerization	GO Biological Process Annotations 2023	1.0	null
STX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23909
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21842
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1512
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
bile duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102793
Inherited metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
tyrosinemia type i	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.58005
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89666
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Vegetation	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97993
KCTD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17981
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.067545
superficial stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55325
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K75853175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43365
Exosome (RNase complex)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.752
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04275
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33046
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088327
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein homooligomerization	GO Biological Process Annotations 2023	1.0	null
Hepatocarcinogenesis	DisGeNET Gene-Disease Associations	1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
TET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37345
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82544
significant	GeneRIF Biological Term Annotations	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K50931403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6913
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.451
other	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67002
KIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32511
Mitochondrial fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC9692021-Table_4.xlsx-Table_S4-Table_S4_405_DEGs_of_RA_synovial_tissues_between_NFIL3-high_and_NFIL3-low_group_NFIL3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36320220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47976
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
BRD-K98586629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32821
enhanced	GeneRIF Biological Term Annotations	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879838
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.365
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Eleocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.396
Microbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.783
MFM-223	COSMIC Cell Line Gene CNV Profiles	1.0	2.09073
rna	GeneRIF Biological Term Annotations	1.0	null
BRD-K43834805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0283
Perturb_12320_KD_PRMT1_SRP165280	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Cirrhosis, Alcoholic	DisGeNET Gene-Disease Associations	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06119
abnormal amino acid level	MPO Gene-Phenotype Associations	1.0	null
GSE216538_5_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47906308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03295
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.71182
PMC5889290-koni-07-04-1412909-s001.xlsx-GSC-exo_vs_Fibro-exo_stat_sign-Gene_name_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.23201
Perturb_15127_KO_Mettl3_SRP363779	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982908
Crohn Disease	DisGeNET Gene-Disease Associations	1.0	null
ZFYVE21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08177
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.77709
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3991
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871739
lateral portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935654
carbohydrate derivative biosynthetic process	GO Biological Process Annotations 2015	1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	1.0	0.953553
Bile duct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920562
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.85344
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_6431_KD_ADAR_SRP268834	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.68643
PMC3315189__F1	PFOCR Pathway Figure Associations 2024	1.0	null
KMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11867
BRD-K16641781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86599
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3922
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.09073
Perturb_10694_KD_Kat7_SRP174052	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
LOX IMVI	BioGPS Cell Line Gene Expression Profiles	1.0	1.04489
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04477
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
BRD-K76738405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46314
Inferior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
Petiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.993
UNC45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62199
GTEX-RU1J-0426-SM-46MUK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A198-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15794
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43877
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10591418-12711_2023_849_MOESM11_ESM.xls-AA_1W_vs_LS_1W-gene_name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5WG-1026-SM-4LMIF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K37486644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57299
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76204
SK-MEL-2	GDSC Cell Line Gene Expression Profiles	1.0	1.50586
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14376
Glutamate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.98
BRD-K90934902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06926
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.422
SW1353	CCLE Cell Line Gene Expression Profiles	1.0	1.77048
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06855
Defective UGT1A4 causes hyperbilirubinemia	Reactome Pathways 2014	1.0	null
BRD-K55642725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56973
BRD-K54364215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09488
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
Arsenic	CTD Gene-Chemical Interactions	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.694
Fetalliver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K52218664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05401
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
well	GeneRIF Biological Term Annotations	1.0	null
PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6870463-Table_7.xlsx-Family_H_LPS-LPS_treatment_of_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A69E-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11441
Cognition Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Olfactory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03922
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.9984
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.807982
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ASPSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17964
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
strongly	GeneRIF Biological Term Annotations	1.0	null
BRD-K32943057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06812
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC8410083-elife-65574-fig7-data1.xlsx-KLF10_network-Unnamed_25_KLF10	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
usually	GeneRIF Biological Term Annotations	1.0	null
BRD-K68758594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83971
NCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54547
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58534227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04616
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K32146668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43835
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_10885_KD_Mafg_SRP165897	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.69834
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87858
Cholestasis	CTD Gene-Disease Associations	1.0	1.49356
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38205
hTERT-HSC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36367
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
RL952	CCLE Cell Line Gene Expression Profiles	1.0	1.36281
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC5571732__F1	PFOCR Pathway Figure Associations 2024	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23774
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.405
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135905
BRD-K88150784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22249
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53639
PECAPJ41CLONED2	DepMap CRISPR Gene Dependency	1.0	6.32549
ribonucleoside metabolic process	GO Biological Process Annotations 2015	1.0	null
PACS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00939
increased inflammatory response	MPO Gene-Phenotype Associations	1.0	null
KAT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SW620	DepMap CRISPR Gene Dependency	1.0	2.17085
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3626
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SELENOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47406
Perturb_16001_KO_TP53_SRP261893	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Central Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
HCC1937	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51066
Pericycle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
ZC3H8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02349
export	GeneRIF Biological Term Annotations	1.0	null
HEP-3B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.679
GTEX-Q2AH-0926-SM-48TZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02129
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K10130686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07665
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12088
GTEX-T5JW-0226-SM-4DM7I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10259
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05309
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32186
Proboscis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K07770425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26714
FOXA2	ChEA Transcription Factor Targets	1.0	null
Liver cancer stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.511
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
NCI-H2452	GDSC Cell Line Gene Expression Profiles	-1.0	-2.18786
BRD-K56424158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14491
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23728
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11409
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835098
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.882206
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2644
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06797
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.52748
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE10	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.10933
Chloroplast thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
Influenza_B Cell Lymphocyte_GSE3203	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.45238
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45208
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79429
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
methylprednisolone_rattus norvegicus_gpl341_gds972	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K59744424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09096
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PMC7714782__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
first	GeneRIF Biological Term Annotations	1.0	null
Perturb_11007_KO_Olah_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.98769
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Hepatic methionine adenosyltransferase deficiency	ClinVar Gene-Phenotype Associations 2025	1.0	null
BTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2065
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38613
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13062
BRD-K47441131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31702
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V955-0326-SM-4JBGV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43228
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05666
PMC12260418-pnas.2425984122.sd02.xlsx-TEAD1_6fraction_test_result-Unnamed_3_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8064_KD_GFER_SRP239459	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.65283
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.601487
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39326623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14355
Hyperplasia	CTD Gene-Disease Associations	1.0	2.88009
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950279
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07574
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02191
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hypermethioninemia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K50599016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00936
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
MAX	ENCODE Transcription Factor Targets	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.11775
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61743
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26332
Parenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.286
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056386
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Photosystem II oxygen evolving complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32476586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3663
Palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.023
PMC9068765-41467_2022_29960_MOESM14_ESM.xlsx-TP53-Annotation_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K37657049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0211
BRD-K03957217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77081
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71847
deadbox	GeneRIF Biological Term Annotations	1.0	null
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
triglyceride-rich plasma lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.855
ESR1-17901129-mouse liver-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K89432538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42361
SW1710	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99226
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_766_mouse_Skin - 0 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NOTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48824
displayed	GeneRIF Biological Term Annotations	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.602892
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14137
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05157
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
DNAJA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14201
SUDHL6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	3.79131
CRCGN009_HEPG2_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20866
Perturb_10998_KO_Lyplal1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.57529
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46753
Perianth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.059
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
downregulated	GeneRIF Biological Term Annotations	1.0	null
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23717
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.38515
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509965
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0025
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06152
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.71104
IHF-DNA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45714931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76462
parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.093695
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74448
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2895
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973157
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67979
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157233_1_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.893917
polyunsaturated	GeneRIF Biological Term Annotations	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
mRNA_STAT3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BRD-A64985224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07116
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCCC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00623328
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BT20	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.92862
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1881
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K66214486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32329
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85802
MYD88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77831
NSMCE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33054
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
glutamate-cysteine ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.192
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
ATPase dependent transmembrane transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
BRD-K65314728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.9108
root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.726918
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
Lignifying cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48415
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955882
Protein storage vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.256
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086798
BRD-K97526959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7387
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_8417_KO_Srsf1_SRP252896	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.17344
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03293
GSE218060_1_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cebp	GeneRIF Biological Term Annotations	1.0	null
BRD-K45498945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36904
Dentate gyrus, granule cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30446
BRD-K94993773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26829
PMC6439317-Table_4.XLSX-NR2F6-Supplementary_Table_4_Genes_with_significant_correlation_with_NR2F6_NR2F6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27618188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17389
ECE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00615248
BRD-K28912195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38696
bed nucleus of the stria terminalis, mediocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00027
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K87461415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29739
cardiovascular	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4423-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K64215435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57594
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.34529
PMC5612430__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.18226
protoxylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.197616
BRD-K23440419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77811
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.182
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.717
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42591
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.804772
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
S-adenosylmethionine synthetase, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
ethanol_rattus norvegicus_gpl341_gds2107	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21506
alate adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00763
Leaf primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tyrosinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.710378
BRD-K84541452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.217
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832263
snps	GeneRIF Biological Term Annotations	1.0	null
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.08091
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08207
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03404
Folate metabolism	WikiPathways Pathways 2024	1.0	null
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6451
spleen_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
Perturb_14584_KD_ATF3_SRP237943	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36914
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A551-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sulfur compound biosynthetic process	GO Biological Process Annotations 2025	1.0	null
BRD-K12836153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50204
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7211
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0666
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56083
Adult liver stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
COPI-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27084
Perturb_10897_KO_Nr5a2_SRP131036	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.50372
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21253219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04589
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33931
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUSP1_KO_GDS1606_772_mouse_spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A0-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39924
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE210655_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42557763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35881
methionine degradation	HumanCyc Pathways	1.0	null
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.80491
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.41344
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09915
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31252
CAKI1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.834184
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	2.04516
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.042337
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
L-2-Amino-4-Methoxy-Cis-but-3-Enoic Acid	DrugBank Drug Targets	1.0	null
Reticular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65731
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070947
VPS52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0079
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6562
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLB985	Achilles Cell Line Gene Essentiality Profiles	1.0	1.34912
Perturb_8424_KO_DGAT2_ERP114849	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE237040_2_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6804
hsa-miR-4436a	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94184
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
telmisartan_rattus norvegicus_gpl4135_gse29445	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
time	GeneRIF Biological Term Annotations	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88249
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
glycosyl compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909949
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.62631
Bacterial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Stroke	HuGE Navigator Gene-Phenotype Associations	1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045888
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859183
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240896,GSE240899_10_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1214
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
TE1	CCLE Cell Line Gene CNV Profiles	1.0	1.81761
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3083
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.953711
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23765
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56854
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
JURKAT	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.08677
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D1FED24h_vs_D1FAST24h_259_AR-DE-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A549	Achilles Cell Line Gene Essentiality Profiles	1.0	1.16255
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
coordinate	GeneRIF Biological Term Annotations	1.0	null
BRD-K07011015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00739
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24207
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
sulfur compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11255_KO_Nr5a2_SRP131036	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.56624
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Impulsive Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K93956318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22239
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Potassium	HMDB Metabolites of Enzymes	1.0	null
BRD-K25284184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16165
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059166
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04046
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46299
KURAMOCHI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21673
ESR1_T47D_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6442705__F7	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K63364685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09715
CAOV4	DepMap CRISPR Gene Dependency	1.0	4.48749
PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10903_KO_Ppp1r3c_SRP019798	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.17028
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79546
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848635
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21157
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
Thioacetamide	CTD Gene-Chemical Interactions	1.0	null
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.352
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5656
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
ARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38812
PMC11266089-Table3.XLSX-Fig1_Disease_targets-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Obesity	HuGE Navigator Gene-Phenotype Associations	1.0	null
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00463
BRD-K42654859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07854
BRD-K83312314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3839
Lung adenocarcinoma_LUAD_TCGA-78-7146-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93127164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05343
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92043
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K77290793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04008
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OOBK-2025-SM-3LK5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
EFM19	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00905
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4542
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.142
BRD-K13515483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20991
GPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45851
GSE237984_1_v_0_magi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K04036799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5567
BRD-K72073851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47753
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.06425
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
Memory Disorders	CTD Gene-Disease Associations	1.0	1.68148
hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.43464
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919336
THNSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07842
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.36961
Elytron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.34
Raji	GDSC Cell Line Gene Expression Profiles	1.0	2.31595
S-adenosylmethionine biosynthesis	PANTHER Pathways	1.0	null
Perturb_852_KO_Igfbp7_SRP081229	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.90624
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
methionine adenosyltransferase i/iii deficiency	GAD Gene-Disease Associations	1.0	null
hel	HPA Cell Line Gene Expression Profiles	1.0	0.84629
HCC1187	DepMap CRISPR Gene Dependency	1.0	5.93626
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48577
Perturb_4394_KD_EHMT2_SRP290196	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0367
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18197334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01158
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
ATP6V1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01301
Perturb_6748_KO_TDRD3_SRP345494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.95363
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K13229082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68678
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
decreased	GeneRIF Biological Term Annotations	1.0	null
RNA N6-methyladenosine methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.027
artery disease	GWASdb SNP-Disease Associations	1.0	0.096949
Perturb_10932_KO_Lkb1_SRP351964	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.71421
Subgeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.46875
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.5935
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7863-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pole plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.137
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
callus culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.569622
Perturb_18151_KO_Cdk1_SRP287303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.1815
BRD-K76942055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58816
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE201668_0_v_1_ncor2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12513721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71834
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-2426-SM-3NMCL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922489
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-U4B1-0926-SM-4DXUV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.478923
BRD-K57464717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21301
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
hsa-miR-1275	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.779
Lung squamous cell carcinoma_LUSC_TCGA-22-4591-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
postcentral gyrus, left, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895232
Inflorescence apex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
PMC3479095-pone.0047303.s002.xlsx-AA_catabolism-Gene_name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K00502656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51174
STK869906	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
BRD-K50114736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0411
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55106
Polar tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
PMC3315189__F1	PFOCR Pathway Figure Associations 2023	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Drug-Induced Liver Disease	DisGeNET Gene-Phenotype Associations	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10952034-mmc2.xlsx-Table_S1-Table_S1_Pooled_shRNA_screen_analysis_to_identify_genes_selectively_required_for_the_proliferation_of_MYC_overexpressing_cells_Related_to_Figure_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.696989
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07525
fatty	GeneRIF Biological Term Annotations	1.0	null
Familial Generalized Lipodystrophy	DisGeNET Gene-Disease Associations	1.0	null
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19291
BRD-K68435627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20489
GSE248858_5_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Rhp55-Rhp57 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.986
Proplastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.841
BRD-K51278788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06357
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909255
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45733
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88281646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03671
BRD-A21814529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17635
BRD-K66852478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10106
hepatic	GeneRIF Biological Term Annotations	1.0	null
Systemic primary carnitine deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.261
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.43909
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085032
BRD-K63654001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46068
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	13.9298
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57404
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04203
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-331-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
mesenteric vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292079
Granum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.906
proton-transporting V-type ATPase, V1 domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
DV90	CCLE Cell Line Gene Expression Profiles	1.0	1.72444
IGF1	MSigDB Cancer Gene Co-expression Modules	1.0	null
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165337
GSTM1	MSigDB Cancer Gene Co-expression Modules	1.0	null
Perturb_10967_KO_Caskin2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.8109
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mat1a	GeneRIF Biological Term Annotations	1.0	null
adenosyltransferase	GeneRIF Biological Term Annotations	1.0	null
BRD-K31195910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41799
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4396
Edema	CTD Gene-Disease Associations	1.0	1.3311
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.83161
inhibit	GeneRIF Biological Term Annotations	1.0	null
PC14	DepMap CRISPR Gene Dependency	1.0	2.47724
aspartate family amino acid catabolic process	GO Biological Process Annotations 2025	1.0	null
Field CA3, stratum lucidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8028
BRD-K31233830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36405
BRD-K02078126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66267
Beckwith-Wiedemann Syndrome	DisGeNET Gene-Disease Associations	1.0	null
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47825
CRCGN009_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92274
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985101
Cerebral creatine deficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
BRD-K31820800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22651
ESRRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14764
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864447
liver	HPA Tissue Gene Expression Profiles	1.0	2.24804
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56064
Perturb_11250_KO_Med23_SRP027536	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.71996
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.65925
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
lb24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
19334046-TableS3b	GeneSigDB Published Gene Signatures	1.0	null
BRD-K78169765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99549
Perturb_10995_KO_Kmo_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.25073
Digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.529
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938733
hypermethioninemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.53691
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19146
mat2a	GeneRIF Biological Term Annotations	1.0	null
Mesophyll cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
all	HPO Gene-Disease Associations	1.0	null
GSE224969,GSE224971_3_v_9_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Aleurone layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.028
MFE-280	COSMIC Cell Line Gene CNV Profiles	1.0	2.09073
BRD-K64483847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75029
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
proton-transporting two-sector ATPase complex, catalytic domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03655
BRD-K36074653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60717
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69867
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32923
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
spinal dysraphism	GAD Gene-Disease Associations	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2452
E2F4	ENCODE Transcription Factor Targets	1.0	null
PPARGC1A_KO_GDS2391_299_mouse_brain striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.209
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K28522188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20375
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976632
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24151
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K31666794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63584
hsa-miR-1909	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K63858518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04706
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02543
S-adenosylmethionine synthetase	InterPro Predicted Protein Domain Annotations	1.0	null
Apical hook	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.021
BRD-K30298864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39816
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02678
only	GeneRIF Biological Term Annotations	1.0	null
Perturb_11001_KO_Mtnr1b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.80907
GSE186440,GSE186443_3_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_4_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
Measles Chicago-1_24Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71511
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.39881
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07078
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07247
EGI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Fetal Death	CTD Gene-Disease Associations	1.0	1.2818
beta-ketothiolase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
Cytoplasmic exosome (RNase complex)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
Medium chain acyl-CoA dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
oxoacid metabolic process	GO Biological Process Annotations 2015	1.0	null
nrk cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188194
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8851354-Table_5.xlsx-FUS-DDIT3_ruxo_reg_FD-bound-Supplementary_Table_5_Genes_regulated_by_both_FUS-DDIT3_and_ruxolitinib_that_are_FUS-DDIT3_targets_in_MLS_402-91_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11209_KO_Mettl14_SRP339507	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.41486
cause	GeneRIF Biological Term Annotations	1.0	null
a431	HPA Cell Line Gene Expression Profiles	1.0	1.49503
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03535
Wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.307
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86075
hsa-miR-29b	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
BRD-K88385836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40128
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06241
CRCGN012_HEPG2_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82797
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0483
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26348
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52566202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02687
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5088
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8077
BLACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4897
BRD-K93310782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09101
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03655
hnf4a_16714383_e18dot5_liver_lof_mouse_gpl1261_gds1916	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.11841
Perturb_2605_OE_SEPTIN9_SRP159553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49005
Navarixin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.42
BRD-K63171151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27577
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NFYA_01_355	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6377
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35126
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63619
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.238
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18792
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Amino Acid Metabolism, Inherited Disorders	DisGeNET Gene-Disease Associations	1.0	null
BRD-K34258763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33568
Spadix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
ac2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832967
BRD-K77627909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64278
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.117783
BRD-K39597125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45796
PMC11031166-SAG-2302-87_0_Appendix_1_SG_IHDS_(569_genes)_Final_List.xlsx-AP1-Genes_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K94647035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15437
hsa-miR-3185	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
duodenal obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.807718
b95.8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EFM-19	COSMIC Cell Line Gene CNV Profiles	1.0	2.09073
abnormal circulating amino acid level	MPO Gene-Phenotype Associations	1.0	null
Mesocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
IST-MEL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
coenzyme metabolic process	GO Biological Process Annotations 2015	1.0	null
cellular nitrogen compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE167474_1_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186440,GSE186443_6_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.84
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00819
anion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4496
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
protein-cysteine S-palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
Sulfur amino acid metabolism	Reactome Pathways 2014	1.0	null
Homocystinuria	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4alpha_KO_GDS1916_168_mouse_Embryonic liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cysteine and methionine catabolism	WikiPathways Pathways 2024	1.0	null
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09095
HLE	GDSC Cell Line Gene Expression Profiles	1.0	2.02047
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973297
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fh4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
BRD-K34192219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13397
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1082
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_10927_KO_Mettl3_SRP363782	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.13863
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41831
NCIH596	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4809
BRD-K62497619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62304
PMC12035534-gfae237_supplemental_file.pdf-65-IRF2_IRF2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843929
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57576
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905977
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
abnormality of movement	HPO Gene-Disease Associations	1.0	null
Fetal Growth Retardation	DisGeNET Gene-Phenotype Associations	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
S-adenosylmethionine synthetase superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1018
GSE157049,GSE157051_6_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K56373119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01123
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7291
Obesity_Adipose tissue_GSE4692	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	3.39815
Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14245433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2343
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02864
GSE110440_1_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-THRB_THRB	Rummagene Transcription Factor Associations 2026	1.0	null
S-adenosylmethionine synthetase, central domain	InterPro Predicted Protein Domain Annotations	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-495	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CRCGN008_HEPG2_24H:E15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08215
MEG01	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68952
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Plastid thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57173429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0299
ovary_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.13023
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12665
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24721
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07348252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71858
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3804
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC7039202__F3	PFOCR Pathway Figure Associations 2023	1.0	null
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6567
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09552
EPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9123
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0667
PJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14842
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.987726
BRD-K53192330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01808
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5428
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
CRCGN008_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70935
Chaperonin ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
BRD-K80413110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50684
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6671
liminal part of the r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03552
Ethanol effects on histone modifications	WikiPathways Pathways 2024	1.0	null
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.201
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18996
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88292241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54429
BRD-K61520618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31957
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.733
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03773
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K28531276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55175
BRD-K28357534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16044
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.317315
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87000197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77834
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84668
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
hsa-miR-4649-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
Leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.593
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.817
CEBPA	ChEA Transcription Factor Targets	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15531
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.828
GTEX-XBEC-0326-SM-4AT4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04528
BRD-K78192025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06692
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-29c	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
BRD-K13888422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30207
15546871-Table1S	GeneSigDB Published Gene Signatures	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
SIN3A	ENCODE Transcription Factor Targets	1.0	null
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K90821428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04731
Labial palp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
liver inflammation	MPO Gene-Phenotype Associations	1.0	null
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
SKOV3	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.977277
BRD-K52231520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9198
HuH-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
NUDHL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	3.08525
BRD-K62572662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26475
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.53165
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.433757
CFPAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
population	GeneRIF Biological Term Annotations	1.0	null
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956999
Dentate gyrus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47128
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.548
BRD-K44458042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79115
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.925674
BRD-K20745677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18515
coexpression	GeneRIF Biological Term Annotations	1.0	null
hypertension	GWASdb SNP-Disease Associations	1.0	0.572673
Perturb_10596_KO_Nr1h3/Nr1h2_SRP351084	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.66762
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68799
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
15656903-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Perturb_8051_KD_SETD2_SRP167173	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.8271
BRD-K16843478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16459
BRD-K63761383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59681
ZEB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9699
CRCGN011_HEPG2_24H:A11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1358
methionine-importing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.211
GTEX-PWOO-0626-SM-48TZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35077
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Disease	Reactome Pathways 2014	1.0	null
pericarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.585224
J7 hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
Get-1_Deficiency_GDS2629_161_mouse_embryonic skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6275
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ring stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
COPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00017
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14468
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_11311_KO_Bmal1_SRP060295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.07068
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28139
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71938
cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
prevalent	GeneRIF Biological Term Annotations	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040515
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleoside metabolic process	GO Biological Process Annotations 2015	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methionine catabolic process	GO Biological Process Annotations 2023	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79227
apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358919
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25721
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
showed	GeneRIF Biological Term Annotations	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51049
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900085
RCOR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K49864183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1573
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.85694
PMC10290283-biol-2022-0622-sm3.pdf-293-ZNF429_ZNF429	Rummagene Transcription Factor Associations 2026	1.0	null
TC71	Achilles Cell Line Gene Essentiality Profiles	1.0	1.37616
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16429
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27331
mir4853p	GeneRIF Biological Term Annotations	1.0	null
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Companion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
HCC1187	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.55175
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8053_KD_SETD2_SRP167173	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.55941
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.53135
Mpk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3379
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K91202220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33467
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IST1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_12078_KO_Ezh1_SRP060232	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.6247
HUH1	CCLE Cell Line Gene Expression Profiles	1.0	1.4938
aspartate family amino acid catabolic process	GO Biological Process Annotations 2023	1.0	null
BRD-K52854560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17131
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PC3	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Liver Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-XGQ4-2226-SM-4AT4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
s-adenosylmethionine metabolic process	GO Biological Process Annotations 2015	1.0	null
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242054
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25169
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
PMC6366065-13075_2019_1816_MOESM1_ESM.xlsx-DOD_Skin_imputed_log2_median_ce-Name_PIN1	Rummagene Transcription Factor Associations 2026	1.0	null
Hepatitis	CTD Gene-Disease Associations	1.0	1.20097
BRD-K18828858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30776
DSTYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23083
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39992
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4680-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95589
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16661
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.780251
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Primary cell wall cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
14767473-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Perturb_14571_OE_JUN_SRP315909	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Tyrosinemia	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16522
GTEX-WFG7-1026-SM-4LMK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94352
transferase activity, transferring alkyl or aryl (other than methyl) groups	GO Molecular Function Annotations 2015	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03587
male	Phosphosite Textmining Biological Term Annotations	1.0	null
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)	Reactome Pathways 2014	1.0	null
liver	HPA Tissue Protein Expression Profiles	1.0	0.858587
Nonalcoholic Steatohepatitis	DisGeNET Gene-Disease Associations	1.0	null
PMC12062214-41467_2025_59646_MOESM5_ESM.xlsx-HMGA2_activated_repressed-Ensembl_ID_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10767_KO_Nrf2_SRP311380	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.11196
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Root cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
CCDC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00542
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00265
GSE155031_6_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Drug-Induced Acute Liver Injury	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16689
Glycine encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
hct-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256568
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.426109
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A70167453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10999
Perturb_10882_KO_Pck1_SRP363462	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.2917
Nuclear cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11758
SRF	ENCODE Transcription Factor Targets	1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-WCDI-0426-SM-4GIAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86254
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23242
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5343
abnormal immune system physiology	MPO Gene-Phenotype Associations	1.0	null
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11441
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27373956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08331
ascites tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.429547
Se-Adenosylselenomethionine	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-4648	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
S-Adenosylmethionine	DrugBank Drug Targets	1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.76559
Methylation(Mus musculus)	WikiPathways Pathways 2014	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.725229
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_10859_KO_Ahr_SRP326814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50346
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15271
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU475	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68069
LAN-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH2141	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76405
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.129
Methionine	MW Enzyme Metabolite Associations	1.0	null
CRCGN011_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28935
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K91799761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24278
4-aminobutyrate transaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
ESR1-20056654-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Hepa-RG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980232
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K77594363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08937
hyperreflexia	HPO Gene-Disease Associations	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heterocycle biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17745
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Lymph	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57175
hsa-miR-3065-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
enzymatic	GeneRIF Biological Term Annotations	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.032961
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.065335
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29822
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13908
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10484
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Phosphate	HMDB Metabolites of Enzymes	1.0	null
pc3	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
BRCA1_02_202	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61926
BRD-K89724519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03335
Perturb_11177_KO_Sqstm1_SRP214429	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.51784
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4977
TRIM24_knockout_299_GSE19675	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.76061
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3635
LIVF001-025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1298
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39996
previously	GeneRIF Biological Term Annotations	1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.540294
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAOS2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74937
Adenoma	CTD Gene-Disease Associations	1.0	1.18554
BRD-K80044183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16437
GSU	DepMap CRISPR Gene Dependency	1.0	2.03787
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054116
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Renal Insufficiency	CTD Gene-Disease Associations	1.0	1.17134
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.072993
furan	CTD Gene-Chemical Interactions	1.0	null
Clinically Isolated Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Hypoinsulinemic hypoglycemia with hemihypertrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831059
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
coenzyme biosynthetic process	GO Biological Process Annotations 2015	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.905675
Propionic acidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.43816
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K92379545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16482
Corolla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.794792
GSE151160_0_v_1_cd36_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulating	GeneRIF Biological Term Annotations	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
mediated	GeneRIF Biological Term Annotations	1.0	null
BRD-K30436657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09882
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.681
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56076
PMC11252405-41467_2024_50426_MOESM1_ESM.pdf-87-TP73_TP73	Rummagene Transcription Factor Associations 2026	1.0	null
intramuscular adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224398
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07948
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Cobalt	HMDB Metabolites of Enzymes	1.0	null
RBM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10426
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.450657
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00246
BRD-K65392908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17678
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1818
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7105
acids	GeneRIF Biological Term Annotations	1.0	null
BRD-K77480803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42465
BRD-K11672894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4912
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cysteine and methionine metabolism	KEGG Pathways 2026	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
Portal hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
MCAS	CCLE Cell Line Gene CNV Profiles	1.0	1.45902
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57609
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SKMEL5	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412771
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.140217
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	7.20904
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.448346
plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193132
Glaucoma_Retina_GSE3554	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.50528
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53489056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07576
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
B3GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07339
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K35860167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08615
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23995
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glutathione and one carbon metabolism(Mus musculus)	WikiPathways Pathways 2014	1.0	null
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24309
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3935_KO_TFAP2A_SRP273704	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Alcoholic Steatohepatitis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K30326216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20641
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2924
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925651
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.78778
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.12461
other	GAD High Level Gene-Disease Associations	1.0	0.293278
ERCC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35076
ACOD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556089
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2067
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1672
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399114
BRD-K90027990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55943
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I1-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00530465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83818
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NK-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.950442
HNF4A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182835,GSE182836_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22496
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20405
hsa-miR-3125	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
liver cancer stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09164
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08027
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.18882
BRD-K15694916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90417
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8441
GW 441756	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HT-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.603
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01331
Tyrosinemia type I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.308
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06657
KMCH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
CRCGN012_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04043
BICR78	DepMap CRISPR Gene Dependency	1.0	2.08864
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5108
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054428
SIRT3_KO_GDS4817_416_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cns demyelination	HPO Gene-Disease Associations	1.0	null
methionine metabolism	KEGG Pathways	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8288-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cob	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303198
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12501
BRD-K66311249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.05357
BRD-K38273665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0099
GSE155162,GSE155169_1_v_3_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938813
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EC-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933202
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
intellectual disability	HPO Gene-Disease Associations	1.0	null
Paliperidone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
BRD-K66655211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75765
axenic culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.52635
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.369
CYBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27873
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ddx3x	GeneRIF Biological Term Annotations	1.0	null
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01828
lower	GeneRIF Biological Term Annotations	1.0	null
GSE221742,GSE221743_1_v_2_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41259
metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88181
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07678
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58632
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143216
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8422_KO_DGAT2_ERP114849	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
interstitial nucleus of the zona limitans	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23924
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352227
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12698
GSE188382_4_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4667-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K73048554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25626
BRD-K44866331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75666
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11065_KO_Mettl3_SRP363782	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.1257
intestinal obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.143722
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K90138084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01149
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Atherosclerosis_Aorta Smooth Muscle Tissue_GSE420	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.29486
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97784715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20281
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919172
Central cylinder	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
cytosol	GO Cellular Component Annotations 2015	1.0	null
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24904
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52628
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
BRD-K70254692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65656
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045408
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19435
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00168
CORL23	CCLE Cell Line Gene Expression Profiles	1.0	1.57078
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76046
Tiagabine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
Phosphopyruvate hydratase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
pICln-Sm protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.39705
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A05635986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.96595
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.8447
hypertension	GAD Gene-Disease Associations	1.0	null
hsa-miR-1910	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ANTISENSE OLIGONUCLEOTIDES	DGIdb Drug Targets 2026	1.0	3.208
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13291
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32714
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.47089
PMC7226524__F2	PFOCR Pathway Figure Associations 2024	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05318
SP1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1631
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.37275
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.887208
region	GeneRIF Biological Term Annotations	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922546
mRNA_SMAD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-XUW1-0526-SM-4BOP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Prespliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
MZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23118
NQO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.431
BRD-K84800135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16338
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07996284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00337
BRD-K74107343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36409
BRD-K03154735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35849
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08824
hsa-miR-920	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54399
Cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
all	GeneRIF Biological Term Annotations	1.0	null
myc_17159920_cancer_cell_lines_lof_human_gpl570_gds2526	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.182425
BRD-K51104732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30319
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2648
BRD-K64182862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00695
decrease	GeneRIF Biological Term Annotations	1.0	null
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926739
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225144
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1579
Twig	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17629
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16683
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85699
hypermethioninemia, persistent, autosomal dominant, due to methionine adenosyltransferase i/iii deficiency	OMIM Gene-Disease Associations	1.0	null
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077772
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82623
Acrodermatitis enteropathica	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
SEC14L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20079
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05555
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
TP53INP2_KO_GDS5053_277_mouse_Skeletal muscle - SKM-KO	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_9807_OE_EBF4_SRP381947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CEBPB-23403033-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Nonparenchymal liver cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047529
GSE198036,GSE198041_4_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K49526793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11176
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08899
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
r7 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06906
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18075
GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5993681-mmc4.xlsx-Tabelle1-Metacore_analysis_of_SRF_binding_targets_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4650-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE167474_2_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0566
Germ plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.14
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K09663164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33364
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.08723
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24686
BRD-A57353172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11202
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3562
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.95482
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951468
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	0.913913
KMRC20	CCLE Cell Line Gene Expression Profiles	1.0	1.56098
GTEX-QLQ7-1526-SM-2S1QA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07296
PMC4239617__F10	PFOCR Pathway Figure Associations 2024	1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trypanosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.309204
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
liver	GTEx Tissue Gene Expression Profiles	1.0	2.18987
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955979
GSE171269_1_v_2_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PEBP1_KO_GDS4334_617_mouse_Pancreatic beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48731
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6629
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
U178	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34679
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1491
Tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95134
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-23403033-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE216538_5_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40347
status	GeneRIF Biological Term Annotations	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84732
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988224
Nauplius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
SYNCRIP_02_10	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59864
Demyelination	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_11713_KO_Kpna3_ERP009054	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.78568
GTEX-XXEK-0426-SM-4BRVW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
liver inflammation	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K51697315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6213
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Metabolic Syndrome X	HuGE Navigator Gene-Phenotype Associations	1.0	null
mRNA cap methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
abnormal hepatobiliary system morphology	MPO Gene-Phenotype Associations	1.0	null
abnormal liver morphology	MPO Gene-Phenotype Associations	1.0	null
Field CA3, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64055
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.763
CRCGN013_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13149
CLDN18_KO_GDS4961_28_mouse_whole lung tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
HNF4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Field CA3, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52261
FD-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15471
HLF	CCLE Cell Line Gene Expression Profiles	1.0	1.64758
Lymphatic edema_Skin tissue_GSE4333	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.78789
SPOTS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.062
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2489
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55801
Head capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.74
layer 4 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14841
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889602
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55431
GTEX-U8T8-1226-SM-4E3IH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.53868
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30259
ERBB2_knockdown_236_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.59694
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16852
hsa-miR-4510	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
hsa-miR-616	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hypercholesteremia_Hepatic Tissue_GSE3889	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.62892
Perturb_10951_KO_48J19Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.98613
organic cyclic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38583
BRD-K41649962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24651
Asarone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
Perturb_10881_KO_Pck1_SRP363462	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.45302
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58632
SAP30	ENCODE Transcription Factor Targets	1.0	null
Root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.249
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08338
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21541
Bundle sheath cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907792
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07101
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940254
Fatty Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918015
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25057
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34335
BRD-K78907463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54562
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.412
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BHLHE40_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A98208100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09608
Perturb_10979_KO_Dusp13_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.29129
JUND	ENCODE Transcription Factor Targets	1.0	null
BRD-K08759542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07777
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Selenomethionine	HMDB Metabolites of Enzymes	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
BRD-K03715233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9908
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
cysteine biosynthesis	HumanCyc Pathways	1.0	null
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47106
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889358
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18483
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04477
disorder	GeneRIF Biological Term Annotations	1.0	null