association	dataset	threshold value	standardized value
L-5178-Y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859887
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46852
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50002
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4762-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.763
UPF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46478
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
SF-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fibroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
JHU-011 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.406
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
EGR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K59263278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02366
MCF7_BMS-536924_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015766
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rhizome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19051
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	1.0	1.08297
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Mocetinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149464
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0225
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44329
UM-SCC-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.275
BRD-K64748422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.06254
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.74858
F36P	CCLE Cell Line Gene Expression Profiles	1.0	1.65684
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32023
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10385824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.99303
BRD-K59960811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0419
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02443
supramarginal gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.838978
Pairing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.02723
1269_CCDC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.615827
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38929
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.66777
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.08109
CRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36439
BAK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.475
GSE148252_2_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Decitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156513
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76555
ZNF460	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K78818514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71423
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10929
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TSACC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09155
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39977
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.358
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888791
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_PFI-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0253489
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947247
ZNF143	ENCODE Transcription Factor Targets	1.0	null
maintenance of sister chromatid cohesion	GO Biological Process Annotations 2015	1.0	null
A549_Tazemetostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113244
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.714
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.011026
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
Squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.255
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_ABT-737_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120328
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2651
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF764	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K25127909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.83512
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SLR20	CCLE Cell Line Gene CNV Profiles	1.0	1.34454
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30772
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67062
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
Brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
18537972-TableS2	GeneSigDB Published Gene Signatures	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946583
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.128
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25714
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cell Cycle	Reactome Pathways 2014	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Scc2-Scc4 cohesin loading complex	GO Cellular Component Annotations 2023	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38241
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29362
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047997
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31974
GSE136869_1_v_0_lpar2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.36818
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.967288
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440777
A549_Fedratinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211898
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.999499
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.13628
Tongue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.77
A549_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150365
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59997
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46792
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64317863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1398
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70865
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86727
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99278
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138019_4_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Temsirolimus_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0123455
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33949
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.15572
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.621
BRD-K20073772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46865
Choriocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_RG108_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193203
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3188
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22842
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30642
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60107240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70709
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31435
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.366
Fibrosarcoma	DisGeNET Gene-Disease Associations	1.0	null
K562_AZ 960_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196222
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8031
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13569
APLP2_KO_GDS4414_371_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K04731905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.003
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226181_3_v_2_akt1s1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48462
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826851
K562_AZ 960_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0199498
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.582497
K562_Resveratrol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189099
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02133
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.87023
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
laminin-15 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.553
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.172885
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
U2AF1_02_165	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59334
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.15143
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58795
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
BRD-K45318035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52568
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Biliary tract cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17149
Gingiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.067
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.23158
BRD-K53901855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07725
intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K53335788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44467
nucleoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_3-Supplementary_Table_3_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_ADHD_significant_association_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75186244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23763
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04788
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09801
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	1.40001
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4854-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10093
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05077
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43361
Palate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.301
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
E2F1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6519
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.09153
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17198
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2177
ChIP_DMAP1_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.0426
IZ in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02495
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09842
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PHF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04661
Triglycerides	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.75229
oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.976323
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422026
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73697974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76175
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45013226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2174
Mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.574
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2086
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80465
chorion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SARS-dORF6_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.7827
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6095
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TF1	CCLE Cell Line Gene CNV Profiles	1.0	1.61007
Perturb_16665_KO_Slc27a2_SRP186493	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.88815
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8167
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.565083
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25755
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95806
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
b104	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09854
K562_Trichostatin A_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0341999
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1836	CCLE Cell Line Gene Expression Profiles	1.0	1.53119
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.210894
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14867
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Breast disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
NARF	Pathway Commons Protein-Protein Interactions	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.18849
BRD-K94344573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50615
HCFC1-20581084-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
NCI-H2405	GDSC Cell Line Gene Expression Profiles	-1.0	-2.4456
HSC-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.086
HS-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DAUDI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Luminespib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126626
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54129
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.368
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
GSE180813,GSE180815_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143643,GSE143644_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7552
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29965
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fipexide-5737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary endosperm nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.835
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66776
HDAC1	ENCODE Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.71633
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.842405
Head and neck cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.506
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64307
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05269
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845798
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5507
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77763
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922659
BRD-K21671578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49733
Esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.90845
A549_Maraviroc_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148594
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.469
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87694
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848528
clorgiline-3219	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55662526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00007
SW780	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45449
MDA-MB-453 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
SAGA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49838
MCF7_Maraviroc_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169184
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78762661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16468
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.82271
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26948
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61017
chromosome, centromeric core domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_UNC1999_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128959
hsa-miR-185	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
l929s	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.791022
GSE153258_1_v_0_dcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13267130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93638
Crohn's disease_Intestine - Large Intestine - Colon (MMHCC)_GSE6731	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.66313
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17025
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26963
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_PD98059_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203736
BRD-K01071579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0113
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22465
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
Thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13249
MCF7_EED226_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0230964
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056732
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ADNP	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18436
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.12987
GSE114992,GSE114993_7_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
t62-spleen_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.76419
E2F4	ENCODE Transcription Factor Targets	1.0	null
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24252
hsa-miR-4742-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCV JFH1_96Hour-Huh7_5_1c2_None_GSE29889	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	4.26671
GSE223008_6_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mitotic checkpoint complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_IOX2_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.02015
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03877
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66202
MCF7_NVP-BSK805 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0127102
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.938664
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.226925
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.649
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44983
BRD-K74908937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27285
chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.311014
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prestwick-674-3614	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.25
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.13433
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromatin	GeneRIF Biological Term Annotations	1.0	null
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48737
7515_RPS26_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.654915
HGF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
prophase	GeneRIF Biological Term Annotations	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Sjnkp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.579
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32574
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24198
Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111247_14_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.927162
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29638
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44741
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46248
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65907
Bcl-2 family protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.472
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05973
DB	CCLE Cell Line Gene Expression Profiles	1.0	2.60535
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.493
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
FOXO3	ChEA Transcription Factor Targets	1.0	null
choriocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Cyclocytidine HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0207243
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gabapentin-5875	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSK3A_knockdown_205_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.63409
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33526
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17935
hsa-miR-4793-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29682
colon	HPA Tissue Gene Expression Profiles	-1.0	-0.846454
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Reticulate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.296
Cohesin loading factor	InterPro Predicted Protein Domain Annotations	1.0	null
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34163
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07567
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897233
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	GDSC Cell Line Gene Expression Profiles	1.0	1.93793
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203182
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_9_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_ZM 447439_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016952
CDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0148
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855352
BT-474 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
la7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985208
GSE196540,GSE196542_2_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558795
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.457
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2369
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GINS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22724
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GSE149943_1_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPMI7951_SKIN	CCLE Cell Line Proteomics	1.0	2.75816
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.685
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.939724
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01756
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6096
BL2230 (FIGNL1)	NURSA Protein Complexes	1.0	null
BRD-K70315531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18014
Larynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.435
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21176
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUV39H2	Pathway Commons Protein-Protein Interactions	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.15887
A549_Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01594
ZNF227	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04599
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10167
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52626
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77891
CRCGN010_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10354
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0822
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
RSP5-BUL ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.196
MCF7_Droxinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174963
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Box H/ACA snoRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.824
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27236
Oropharyngeal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPNA2	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_MK-5108_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0127291
MCF7_Trichostatin A_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012739
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.96705
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31485
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1931
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A719-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	0.928996
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63330804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36519
PML	ENCODE Transcription Factor Targets	1.0	null
CDCA8	Pathway Commons Protein-Protein Interactions	1.0	null
4161_IPO13_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.569406
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81745
MCF7_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157698
Tetratricopeptide-like helical domain	InterPro Predicted Protein Domain Annotations	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11761
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-19p13_overlap_Rifatbegovic2018-DCX-KD__CHR19p13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87901
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21919
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.365
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
maintenance of mitotic sister chromatid cohesion	GO Biological Process Annotations 2015	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08697
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56154
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCMV_24Hour-AG_pretreatment_20173022_GSE17948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.33198
SK-MES-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56623
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149439
pparg_21068720_macrophage_c57bl6_lof_mouse_gpl1261_gds4370	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.336847
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65338
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.97502
Perturb_14240_KO_Mtor_SRP106468	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31492
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15095
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50881
BCL7A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.583126
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33102216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08189
ZNF689	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ETS1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11138
TGBC1TKB	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48652
K562_WHI-P154_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0227397
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852532
tongue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196613
chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.265
OVCAR-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15067
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.916544
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2201
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.08762
Colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.783
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92118
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.49652
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2476
BRD-K91813753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3638
Red cell distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.65229
Subtelomeric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15476
Yoshida sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Amisulpride_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191968
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10089
ZNF701	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27927
BRD-K70895130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09339
MCF7_Capecitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147609
delsoline-7212	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1227	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Thymus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43796
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06445
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6843-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
K562_Tucidinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162778
MCF7_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147585
lycorine-4365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-fromNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mau2	GeneRIF Biological Term Annotations	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.12006
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02856
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Malignant ovarian surface epithelial-stromal neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63433
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175745
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49727
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0354
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956791
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52978625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10645
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938882
Mdr2_KO_GDS1990_286_mouse_Livers of 12 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Rpd3L complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Crizotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136059
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SGOL1	Pathway Commons Protein-Protein Interactions	1.0	null
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10115
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21803
SKMEL2	BioGPS Cell Line Gene Expression Profiles	1.0	1.37761
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911777
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52107
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Divalproex Sodium_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190101
Cohesin complex Cornelia de Lange syndrome	WikiPathways Pathways 2024	1.0	null
Gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26987
K562_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148851
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63199
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844327
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0726-SM-3TW8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51311
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00815
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883825
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3922-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
sotalol-4079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47694
Ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24801
NCI-H2126	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65899
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.798
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
colo320dm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
CAL851_BREAST	CCLE Cell Line Proteomics	1.0	2.06662
PMF1	Pathway Commons Protein-Protein Interactions	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7434
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.84296
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
tretinoin-447	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.610875
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90862
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Fasudil_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173177
BRD-K98117883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18373
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE148252_5_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18824
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03207
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21412
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Eyelid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4914
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.570913
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03756
pentolonium-4699	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.26165
FaDu cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.448
JUND	ENCODE Transcription Factor Targets	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38946705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17366
Rucaparib (phosphate)_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00300376
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884133
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21886
BRD-K22970494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22982
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YJ-A8SW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCDC186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6349
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.894482
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37871
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22152
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81659
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02063
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27236794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5307
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28297
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
Gonadal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03577
2203_DHX15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.673635
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93816
BRD-K21648400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28567
GTEX-WEY5-1226-SM-4LMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0935
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87392
BRD-K04378630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10669
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bu25tk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00996
BRD-K39695412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19822
BRD-K66352426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18535
LNCaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z3-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89307
S-isopropylisothiourea	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31578
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.783
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
Laryngeal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.713
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.36195
ZBTB33_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glioblastoma multiforme cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
MDM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536168
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938178
Mitotic Telophase/Cytokinesis	Reactome Pathways 2014	1.0	null
Hepa-RG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890367
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.211934
Type III protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-3617	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.79
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE121857_2_v_1_sin3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.603664
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249006
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09595
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.959685
Larynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.896
Condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.103
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888795
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23088
NCIH524	CCLE Cell Line Gene Expression Profiles	1.0	1.40722
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SJ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76904668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25536
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912084
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SMARCC2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KNS81	CCLE Cell Line Gene CNV Profiles	1.0	1.53918
chromatin	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04421
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Colo-320 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cataract	IMPC Knockout Mouse Phenotypes	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1549
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF415	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64597
MCF7_Barasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140309
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37143
boldine-4004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMG complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
GSE242199_2_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24481
A549_SGI-1776 free base_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190964
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983371
isosorbide-6038	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43654
BRD-K23997756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19971
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976833
Tongue Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Laryngeal squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
Aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.242
BRD-K68002543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39034
MCF7_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153279
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Trichostatin A_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0235231
NCIH520	CCLE Cell Line Gene CNV Profiles	-1.0	-2.31057
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5FP-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_G007-LK_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185479
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MCF7_Costunolide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184836
Polytene chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23819
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900037
non-small cell lung adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.534
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3828
Squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.464
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE180_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.14641
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28707
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.74151
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34297
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06773
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824597
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16305
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42389
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1435	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95897
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-1.01007
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Selisistat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206375
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
morula	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043031
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.456732
SIX5_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
DA-17-YW85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28524
Spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.303
THYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66211
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.15944
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08065
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27537
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24927
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51193
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EI-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
K562_ENMD-2076_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177273
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RN-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW-480 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75756
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.986
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Anacardic Acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149525
BRD-K50046044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3859
yeast	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27638063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17053
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CDK8_knockdown_129_GSE30816	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.44263
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2104
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40G-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Berry	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.633
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8712
MCF7_Linifanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152923
Stiripentol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21181
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2647
UM-SCC-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22396
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21293
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4276
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.523545
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.71599
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42974
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9255
0173570-0000-4715	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86707
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZW-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53447
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37291
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10748
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hel299	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Cul7-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.933276
Mitotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.641
Acute leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.27436
ARID3A	ENCODE Transcription Factor Targets	1.0	null
K562_Ellagic acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0278548
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56141
K562_GSK J1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0264687
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949368
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203658
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95059
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949368
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68576
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE205976,GSE205978_3_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
RCM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46751
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.31223
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09294
MCF7_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015469
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Capecitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206652
preweaning lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Replication fork protection complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.21
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64166
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34676
GSE102870_7_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0085
KDM5A	ENCODE Transcription Factor Targets	1.0	null
CGTHW1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33308
JF-96-HH81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246237
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14164
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K44956383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68561
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062736
K562_Tucidinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0121454
ganciclovir-6289	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19354
A-2780 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HTC-C3	GDSC Cell Line Gene Expression Profiles	1.0	1.71302
Vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.686
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859781
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052202
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39327
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927178
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20728
K562_SRT2104_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163568
zalcitabine-4215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UO31	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.02378
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.61128
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997322
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
egr1_20019881_retina_lof_mouse_gpl1261_gds3607	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.19749
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
IPC298	CCLE Cell Line Gene CNV Profiles	1.0	1.49641
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44894
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11196
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62788
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937776
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-760	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
Congenital hypoplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15631
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K33005275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41475
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.959665
Chromatin factors	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.985
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07418
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.909792
MCF7_Cerdulatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153868
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916145
K562_TGX-221_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0227112
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6495
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.404
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1351
Thorax	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74715
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EHMT2	Pathway Commons Protein-Protein Interactions	1.0	null
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926799
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_5-Supplementary_Table_5A_Results_of_bulk_tissue_eQTL_MR_analysis_for_causal_effects_of_genes_on_ADHD_significant_association_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833219
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058559
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884133
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21381
RLF	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
KP4_PANCREAS	CCLE Cell Line Proteomics	1.0	5.91614
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.781287
K562_XAV-939_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0224636
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Carmofur_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018032
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76229
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96817
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16981
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.708
BRD-K63950697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04226
BRD-K99805333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2346
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_7_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12107215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33948
K562_Tacedinaline_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135842
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33687
Cervical adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
MDA-MB-435S cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
Chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.538
Larynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.731
ZSCAN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09725
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60266
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SE-81-RI20_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225239
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39734
Hypopharyngeal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.447
A549_Decitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0219701
MCF7_Sirtinol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151275
K562_Nilotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190652
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68697
dg2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
176_AFG3L2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.631565
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RC-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A68865339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12212
BRD-K95937143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15221
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893178
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59177
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.42853
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H6-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96776591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77522
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831266
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.64371
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06026
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20523
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899659
BRD-K08715132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58786
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39714
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.734
ZBTB33_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910085
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85585
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48546
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25106
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3156-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
K562_Regorafenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183252
MRPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53045
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04058
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315698
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0026
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02074
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55657
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87275815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57539
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47012
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-28 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
MCF7_Mesna_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0208088
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4081
organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18106
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
terconazole-4407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24013
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362042
761_BARD1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.66793
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06734
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AX-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nuclear part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.993893
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53778
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77112
K562_Ivosidenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179183
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04409
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.217856
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.711
ATF2	ENCODE Transcription Factor Targets	1.0	null
aciclovir-5278	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908355
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.99264
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARHGEF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20602
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8399-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.828843
8382_SPTA1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.688347
Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.78529
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00212
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03404
Experimental Organism Basal Cell Carcinoma	DisGeNET Gene-Phenotype Associations	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6299
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057674
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RBBP7	Pathway Commons Protein-Protein Interactions	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IS-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.008
Replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.835
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01155
family	GeneRIF Biological Term Annotations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
non-small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.594
3816_HLX_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.533885
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87176777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15462
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829671
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876229
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70989
PMC12695649-41588_2025_2389_MOESM2_ESM.xlsx-GATA6_RIME-_AsPC-1-Gene_Symbol_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE3583	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.908544
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00651
GSE202434,GSE202438_12_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29129
CHAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K19734887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09104
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996068
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77177732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00439
hsa-miR-3143	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
MRC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.24
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36906
TRIM28	ENCODE Transcription Factor Targets	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
THAP11-20581084-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Multiple myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.479
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LA-10-VZ79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209685
K562_Ki8751_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145774
GSE223008_6_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Inner kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.348
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29901
K562_Rigosertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206028
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69996
nystatin-4223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_G007-LK_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018971
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCO2	CCLE Cell Line Gene Expression Profiles	1.0	1.68904
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44141
BRD-A12822115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04426
DSIF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_down-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.06082
ZBTB33_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1944	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92527
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03877
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14894
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052413
thymus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224117
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82726
thiamazole-3815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7421-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865193
trophoblast	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11701
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00665
rhombomere 9	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15312
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95962
BRD-K25103635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09935
BRD-K63188051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13563
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-549 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01141
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284752
Nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.167
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83885
(-)-atenolol-6725	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66759
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10576
K562_Fasudil_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176601
specific	GeneRIF Biological Term Annotations	1.0	null
KBM-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
A-CA-04-2009(H1N1)_6Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.26118
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.25547
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39923
MAFF	ENCODE Transcription Factor Targets	1.0	null
CCF-STTG1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.508553
MCF7_Tie2 kinase inhibitor_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014602
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02727
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.33305
BRD-A20256229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66065
ZNF773	Pathway Commons Protein-Protein Interactions	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE160017,GSE160022_1_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05191
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60731
KPNA4	Pathway Commons Protein-Protein Interactions	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00652
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.935995
Mouth floor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.728
DB	GDSC Cell Line Gene Expression Profiles	1.0	2.59694
Cornelia De Lange Syndrome	DisGeNET Gene-Disease Associations	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864397
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.40773
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09658
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.26165
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZY-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POGZ	Pathway Commons Protein-Protein Interactions	1.0	null
Transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
corl88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6371
K562_SL-327_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142897
Ovarian serous carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99207
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Momelotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178618
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Foreskin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5979
Nuclear body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65605
Isw1b complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.74
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.26165
GSE169152_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883007
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.352
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239578_0_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_AG-490_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155776
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75203
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93733
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49419779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24558
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MV411	CCLE Cell Line Gene Expression Profiles	1.0	2.30636
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K17285234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54527
RELA	ENCODE Transcription Factor Targets	1.0	null
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78373
U-937 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Lysosomal storage disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.863794
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62145
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Cyclocytidine HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142251
BRD-K36474885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06875
chlorambucil-4345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911029
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
MEIS2_02_30	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59291
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87743988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09606
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K71493640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57983
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24813
Gastric cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.167
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45171
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00724
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15537
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Nasopharyngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
HT-1080 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.164
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29366
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ESR1_ECC-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09565
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.935995
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.851393
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Panobinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169003
BRD-K58286708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07092
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.55401
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Sorafenib Tosylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164126
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.544
HSCC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.577
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
Esophageal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.24
mitotic cell cycle process	GO Biological Process Annotations 2015	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26314
PMC10621121-40101_2023_341_MOESM1_ESM.docx-0-L3MBTL4_L3MBTL4	Rummagene Transcription Factor Associations 2026	1.0	null
OCIAML3	CCLE Cell Line Gene Expression Profiles	1.0	1.56843
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE158834_10_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_UNC1999_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176359
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09452
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_1_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eye cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144231_3_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925611
Perturb_3381_KO_Ptpn2_SRP159185	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.78543
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981622
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47894
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
fulvestrant-2698	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pancreatic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.542
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12857
BL1492 (NIPBL)	NURSA Protein Complexes	1.0	null
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Origin recognition complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.438
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
SK-MEL-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
PPARG	ChEA Transcription Factor Targets	1.0	null
GSE247862,GSE247863_0_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39489370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25222
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07397
DA-17-XI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266438
BICR18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65683
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74902280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02989
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092339
A549_SNS-314 Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132598
hsa-miR-584	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43556
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041771
TP53	ChEA Transcription Factor Targets	1.0	null
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.736499
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SLC35F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15318
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell division	GO Biological Process Annotations 2015	1.0	null
BRD-K92358687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10658
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11688
K562_Entinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0123143
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14798
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5886-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
HL-60 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.769
K562_Bosutinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146621
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	2.12722
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2852
GSE193999,GSE194000_4_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_POU5F1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZMYM3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A88237615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58669
8666_TAF5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.541022
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1747
liminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44053
Acute promyelocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311271
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K03953354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5706
GTEX-T6MO-1126-SM-4DM5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904359
gabapentin-2731	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47157
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75365
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54067431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10796
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1118
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_AMG-900_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151727
SF172	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56068
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_SRT1720 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133108
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911864
ALEXANDERCELLS	CCLE Cell Line Gene CNV Profiles	1.0	2.64361
bound	GeneRIF Biological Term Annotations	1.0	null
Cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.922
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4067
Squamous Cell Carcinoma Of Tongue	DisGeNET Gene-Disease Associations	1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MB-49-LL22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243356
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.944512
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
ERI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17868
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61520618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76822
MCF7_PD173074_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0231434
Lung squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73408
KG-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14261
GEO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.37816
picrotoxinin-2161	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.0
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Serum Total Cholesterol Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
PMC12254212-42003_2025_8449_MOESM4_ESM.xlsx-Sheet1-Proteins_in_the_AR_core_AR	Rummagene Transcription Factor Associations 2026	1.0	null
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
messa/dx5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.227
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_26_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
vertebral transformation	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865762
BRD-K42279779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10708
Vas efferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.648
BRD-K42789863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20773
CC-48-OM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211375
JHOM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91846
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28128
Medial geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7884-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83139520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86746
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40464
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20898
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ALL-PO	GDSC Cell Line Gene Expression Profiles	1.0	2.67454
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90024
BRD-K63908919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03187
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865195
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06351
mantle zone of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72793
GSE172146_2_v_1_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876043
UM-SCC-17A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.17074
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WS-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tongue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.593
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065298
RBPJ	ChEA Transcription Factor Targets	1.0	null
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.52009
Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
nucleus	GO Cellular Component Annotations 2023	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BL1476 (PNKP)	NURSA Protein Complexes	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44802
EF-52-ML96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263737
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_filtered-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Estimated glomerular filtration rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.722185
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898358
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72161
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05632
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.09148
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864563
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.8302
MCF7_Tacedinaline_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154905
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.43067
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9562
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13599
NCIH1944	CCLE Cell Line Gene Expression Profiles	-1.0	-2.99255
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.951
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26378
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38524
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02485
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_10_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.13518
OECM-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.634
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
oxantel-6738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBX5	ChEA Transcription Factor Targets	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01603
hsa-miR-1278	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859993
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Tozasertib_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152668
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
UM-SCC-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.19
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20437
Ovarian cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
Nasopharyngeal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
Lung squamous cell carcinoma_LUSC_TCGA-43-7656-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-266 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.496
BRD-K05969019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25713
BRD-A96334094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21307
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113221,GSE113968_6_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50196
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6436
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
Protein phosphatase type 2A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.505
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48152
HEC50B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09439
Intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.805
HCC1395	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
K562_INO-1001_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177004
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09315
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Plateletcrit	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.33979
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76619
GSE134986_2_v_8_oma1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11462941-CAS-115-2947-s001.pdf-175-ZGLP1_ZGLP1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45034
NCIH2172	CCLE Cell Line Gene CNV Profiles	1.0	1.8831
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23989
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sw837	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052188
BRD-K66494817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30907
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73762
BRD-K10459972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01014
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2952
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.56958
1458_CDT1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.658556
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.551
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906273
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
hsa-miR-2115	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
BRD-K89891928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06631
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.728
MCF7_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203912
BRD-A41916216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10392
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ATP5MC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23933
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7428-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
NAD(P)H dehydrogenase complex (plastoquinone)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.836
Perturb_1650_KO_Tnfaip3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.66837
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957659
CTCF	ENCODE Transcription Factor Targets	1.0	null
BMPR1A_knockout_222_GSE48092	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.08492
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02405
hsa-miR-92a-3p	MiRTarBase microRNA Targets	1.0	null
THAP11	ChEA Transcription Factor Targets	1.0	null
NCIH838	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80063
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8331-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59005
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
BRD-K72821236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66485
ZNF384	ENCODE Transcription Factor Targets	1.0	null
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.34412
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62223
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.565906
K562_Carmofur_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015545
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00247
Pharyngeal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.319
Mrsa - Methicillin Resistant Staphylococcus Aureus Infection	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936892
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52551
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.482
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11597
ZNF483	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K99581286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24642
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13163
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.332
hsa-miR-4492	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4424
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCC-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.248
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oral squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319863
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VPS72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0063
dilazep-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96526
Breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.986
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0899
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35719
protein-containing complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
A549_Entacapone_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146898
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68583
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
RP1_KO_GDS1845_190_mouse_Retinas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ncih1650	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
MAPK14_knockout_13_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.49754
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
K562_Fluorouracil_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148411
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03377
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056276
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Response to fenofibrate (LDL cholesterol levels)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
periventricular stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21164
Tonsil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31789
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20396
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A0-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43735
RBL1_KO_GDS1931_740_mouse_Neurospheres (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12415
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.704576
Elg1 RFC-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.572
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.996084
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17894
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.786
K562_Celecoxib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0214144
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Daphnetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184495
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
SP4	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850074
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2086
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0177
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27056
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.54135
GSE151782_3_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_UNC1999_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204484
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
AC-36-SY22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232508
MCF7_Lomustine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160908
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839662
K562_JNJ-26854165_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.026562
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Daphnetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169205
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29276
oe19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37975989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41137
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Karyomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.959
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40932
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_RG108_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159873
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.840992
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.868773
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22696
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42195
POU2F2	ENCODE Transcription Factor Targets	1.0	null
keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.273696
A549_Veliparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013884
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Granum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.77565
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.872216
etamsylate-4399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08149
Tongue cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.173
MOTN1	CCLE Cell Line Gene Expression Profiles	1.0	1.38367
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939117
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13877
MCF7_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142875
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
trunk	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13358
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297431
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69478
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8892
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hep-G2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.672
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_CEP-33779_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193605
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79603
SYK_druginhibition_281_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.7799
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62492257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01355
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO-357 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
XE-29-LT20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241394
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42736
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01445
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0487
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28055
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38874
spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04885
SK-N-MC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL26L1	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_AZD1480_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191435
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9686_UTP3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.808894
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
BRD-K94993773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43412
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1312
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04771
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
IZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835303
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57437
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3289
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11004
clozapine-2689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_Enzastaurin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.020959
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836227
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10007
NCIH1618	CCLE Cell Line Gene Expression Profiles	1.0	2.27066
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNA polymerase II, holoenzyme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.36
H-1299	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
Kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.92
Tongue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.791
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI-8226 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.034
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.775
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.712211
MDA-MB-468 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
Gum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87737
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0293
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43109
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27102
SIX5	ENCODE Transcription Factor Targets	1.0	null
A549_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155809
SFRP5_KO_GDS4988_27_mouse_gonadal white adipose tissue HFD	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917634
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.106
single-organism process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K46494135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32563
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.572578
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55769
protoveratrine A-2144	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
M Phase	Reactome Pathways 2024	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942462
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19926
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40986
AA-87-EI21_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402523
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSTO-211H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
reduced	GeneRIF Biological Term Annotations	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
Nasopharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06697
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25376
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-2.3084
SARS-dORF6_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.11578
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.825634
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31034
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.38851
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35066174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62107
BRD-K09711841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15807
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
KDM1A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4668-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
MOLT-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220934
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0148
Epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.273
BRD-K99000702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40705
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Mercaptopurine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155421
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.798
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150827
RCOR1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-660	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08006
Inherited metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00316
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03644
MOGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30721
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Entacapone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.021946
BRD-K84792324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69647
BRD-K39379715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2335
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colorectal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
8-M-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12317
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
IZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12952
WHSC1	ENCODE Transcription Factor Targets	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897451
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973386
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurological pain disorder_Dorsal Root Ganglia_GSE15041	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	3.45196
ZNF566	Pathway Commons Protein-Protein Interactions	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325655
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43847
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13876
MCF7_Nilotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144297
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.78072
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0969
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MCF7_Tofacitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218743
KPNA3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATG12	Hub Proteins Protein-Protein Interactions	1.0	null
JHU-013 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
BRD-K59335919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20996
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76861469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33109
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
IDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5764
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03675
K562_Barasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139745
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.897
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10861
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HV-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298229
RAMOS-2G6-4C10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98711518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23169
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76292
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Male germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
periventricular stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4572
ZNF274	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28571
A-253 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016837
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19658
IF-92-OK68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205638
Hepatobiliary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866363
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-65-UA27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262265
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kasumi-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
Brain Lower Grade Glioma_LGG_TCGA-DB-5277-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.60352
Chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.417
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0128107
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43121
Rectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
Kinetochore microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.966
MCF7_Nintedanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169811
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.977852
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	1.02727
GSE172490_5_v_3_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Steatotic liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
KYSE-270	GDSC Cell Line Gene Expression Profiles	-1.0	-2.26923
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01654
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.833562
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4M0-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03669
PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF568	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.49549
BRD-K49338297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10842
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02903
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04025
PMC10203545-Table_4.xlsx-LM7_underrepresented-DMRTA1_DMRTA1	Rummagene Transcription Factor Associations 2026	1.0	null
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09752
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP2CB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193258,GSE193259_2_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945581
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9707
protein binding	GO Molecular Function Annotations 2015	1.0	null
PMC11021710__F3	PFOCR Pathway Figure Associations 2024	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37092
K562_BRD4770_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017428
BRD-K13898728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17791
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.189
mantle zone of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37019
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83636
ZBTB33_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65831955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41408
BRD-K34095226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22452
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_SL-327_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017399
Lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.761
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33366
BRD-K82364958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57814
Esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.351
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951695
SAS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.369
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC loading complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060601
Staf	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03608
SP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.936805
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37904
nucleus	GO Cellular Component Annotations 2015	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.157707
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LZTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26656
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.934116
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
8505C_THYROID	CCLE Cell Line Proteomics	1.0	5.38128
(-)-isoprenaline-6149	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47686
7-Hydroxycoumarine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
ZEB1	ENCODE Transcription Factor Targets	1.0	null
Perturb_14525_KO_Foxa2_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.098
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34859
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-SP1_mod_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.510187
MCF7_Cyclocytidine HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0123928
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.32818
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46E-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Azacitidine_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122257
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.7864
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NEPRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39158
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.89029
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52197
MCF7_Sirtinol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0192582
Prostate adenocarcinoma_PRAD_TCGA-VP-A87D-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89393
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
zygote	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Crizotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186909
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87342
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_AC480_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174102
MCF7_PD98059_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137339
BL1999 (DDB1)	NURSA Protein Complexes	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.51042
PMC5998130-41467_2018_4619_MOESM7_ESM.xlsx-specificity_NCOA3-Gene_Name_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85513
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24362
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10935
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58795
alfaxalone-3135	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC3680531-cc-12-1510-s01.pdf-24-SP100_SP100	Rummagene Transcription Factor Associations 2026	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCC-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.503
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
BRD-K12853587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17009
Kidney Chromophobe_KICH_TCGA-KO-8414-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967414
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K75440064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4081
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981188
K562_Nintedanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172637
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47661
Hypopharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Elementary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04196669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20402
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25001
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.984
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44936
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1517
TROVE2	Hub Proteins Protein-Protein Interactions	1.0	null
Tongue cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.377
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53598
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10245
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.344827
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
PMC10750291__F6	PFOCR Pathway Figure Associations 2024	1.0	null
K562_Quercetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.020069
hsa-miR-365	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
BRD-K50950731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03022
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36228
Squamous Cell Carcinoma Of The Head And Neck	DisGeNET Gene-Disease Associations	1.0	null
commissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12009
Mitotic spindle microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
BRD-K63829331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3609
CGTHW1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.3536
Hoxc13_OE_GDS1890_174_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.912349
K562_Fulvestrant_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152999
K562_Thiotepa_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0222098
Pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.909
hsf1_00000000_tcell_lof_mouse_gpl1261_gse41005	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.074568
RELA_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.614774
NCIH1975	CCLE Cell Line Gene CNV Profiles	1.0	2.36179
BxPC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
RERFGC1B	CCLE Cell Line Gene Expression Profiles	1.0	1.90783
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02914
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.062
Ethiprole	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5152
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K91137832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.294
BRD-K38750802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30149
Solid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
Esophageal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
precentral gyrus, left, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.876022
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.503378
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0276
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73539077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06126
15459216-TableA2b	GeneSigDB Published Gene Signatures	1.0	null
PRDM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38208
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
decreased body length	MGI Mouse Phenotype Associations 2023	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16092
pantothenic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52454
Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MCF7_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122511
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5470_NAT10_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.25012
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adult Fibrosarcoma	DisGeNET Gene-Disease Associations	1.0	null
K562_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0418258
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4699-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-acetyl-L-leucine-5683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863596
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7785
MCF7_BMS-536924_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154611
BRD-K95508535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61584
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.335864
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-SP1_mod_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-1526-SM-4AD6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875279
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55835
SOX2_Deficiency_GDS4853_320_human_AZ-521 gastric cancer (GC) cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.5916
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UA-39-TN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247794
APLP2_KO_GDS4414_534_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
chr19_19329619_A_G_b38	GTEx eQTL 2025	1.0	2.22431
T-24 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
HEP-3B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
PMC10081388-media-2.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1892
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-Genes_with_VDR_elements_only_control_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1137
chloropyramine-4589	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3157-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mau2interacting	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-DX-A1KX-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4708-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ChIP_HCIF1_20581084	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE111245_0_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.56122
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02524
Uveal melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
PPP2CA	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.921
methylbenzethonium chloride-2190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31291
HS683	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.24687
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12937
4951_MED28_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.67777
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47058
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.748
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234868
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33673
EBF1	ENCODE Transcription Factor Targets	1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87927
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HO-8910PM	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
A375	CCLE Cell Line Gene Expression Profiles	1.0	1.53975
Adenoid cystic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retrorsine-2129	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
3986_HSPE1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.561007
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
tanespimycin-2685	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCFC1	ChEA Transcription Factor Targets	1.0	null
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94481
ovary	HPA Tissue Gene Expression Profiles	1.0	1.23642
K562_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173689
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLCPRF5	CCLE Cell Line Gene Expression Profiles	1.0	1.61428
CTV-1	GDSC Cell Line Gene Expression Profiles	1.0	1.50526
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.950018
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061575
PMC11880379-41467_2025_57480_MOESM3_ESM.xlsx-SOX9_RIME_Limma-Gene_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.96802
KOSC-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-346	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72793
Thoracic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36151
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.048
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20487
Gingival cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
BRD-K44026015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10439
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12744
K562_PF-573228_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177326
CRCGN015_MCF10A.TP53.M_24H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03423
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.844985
Bipolar I disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.086
PHF8	ChEA Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26758
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
4149_INTS4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.679935
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SF539	BioGPS Cell Line Gene Expression Profiles	1.0	1.64096
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88137
ZBTB33_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97857
DU-145 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.665
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04462
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.406
neostigmine bromide-6735	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30587
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZBTB33_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43847
GNAI3	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K50445566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12634
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830046
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07235
MCF7_Carmofur_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149577
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65618
Trunk	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE154464_1_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.208137
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38295
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.17
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835011
atropine methonitrate-3116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DNA polymerase III, clamp loader complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.283
BRD-K40732885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18122
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922054
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.704
PDX1_KO_GDS4348_360_mouse_Proximal small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OCIAML5	CCLE Cell Line Gene Expression Profiles	1.0	1.4313
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1	ChEA Transcription Factor Targets	1.0	null
until	GeneRIF Biological Term Annotations	1.0	null
K562_JNJ-7706621_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161794
Perturb_3145_KO_Mrfta/Mrtfb_SRP388810	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.38552
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20582
ZNF620	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-7	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_SRT2104_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177512
Brain Lower Grade Glioma_LGG_TCGA-HW-7493-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
Huntington's Disease_CNS - Brain - Cerebellum (MMHCC)_GSE3248	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.52643
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.19023
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971751
BRD-K47881755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63148
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884133
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.370222
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00563
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167691
SW-620 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
Dbf4-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.996
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26616
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
Tracheal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
MAZ	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40141
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19E-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_8-Supplementary_Table_8A_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_persistent_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.54224
hsa-miR-1292	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TLE2_02_53	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61271
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88533
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
guaifenesin-4371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Laryngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.755
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27356
Postprandial triglyceride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.956922
organelle	GO Cellular Component Annotations 2015	1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
WI-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.866
thorax	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K87404495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52056
BRD-K70050144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16449
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23569
IA-27-CK10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276197
Astrocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.411
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43606
CBX5	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Disulfiram_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187607
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07577
Breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.0
PBX3	ENCODE Transcription Factor Targets	1.0	null
MCF7_Tanespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00931238
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.676
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fasting triglyceride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
AsPC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.238
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03315
19797726-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847374
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223008_5_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25587
MCF7_Ki16425_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0299324
Gingival fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.728
A549_Disulfiram_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167271
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19281
Mesophyll	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
K562_Tofacitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189984
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.809
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Givinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014281
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.85861
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53778
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Nintedanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0290198
Lung adenocarcinoma_LUAD_TCGA-69-7764-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
MITF	ChEA Transcription Factor Targets	1.0	null
u87	HPA Cell Line Gene Expression Profiles	-1.0	-0.832709
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890589
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
10244_ZNF260_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.972318
NCIH520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65484
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.87952
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UM-SCC-22B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13736
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299388
BRD-K74811560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44653
MCF7_Rucaparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0252755
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.075748
ONS76	CCLE Cell Line Gene Expression Profiles	1.0	1.43309
doxorubicin-4610	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ezh2_deficiency_GDS2717_141_mouse_lymph node T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KARPAS299_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.46303
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.94666
Dok	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.219
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20383
SK-MEL-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
BRD-K36736230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1635
Rotavirus infection of children_Peripheral blood mononuclear cell_GSE2729	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.8019
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.725
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
corticosterone-4145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.630318
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OTT1_KO_GDS4315_146_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.949
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11878
chromosomal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35359
RUNX3	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-29c	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
Acute myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.689
A549_Crizotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148211
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38625
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.177154
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1383
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K45315294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6136
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z3-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.597571
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14153
A549_PF-3845_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018429
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71982936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06137
5791_NR2E1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.584558
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETS1	ChEA Transcription Factor Targets	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.99451
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
MCF7_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012562
MCF7_Bisindolylmaleimide IX_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133474
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18603
ZNF324	Pathway Commons Protein-Protein Interactions	1.0	null
liminal part of the r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96111
preweaning lethality, complete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
Salivary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
K562_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0296251
GSE154940_1_v_0_nbdy_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Laryngeal benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35513
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.16947
KLF1	ChEA Transcription Factor Targets	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fludroxycortide-6039	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63213
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32312
LRRK2_mutant_32_GDS4400	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.70033
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Erectile dysfunction_Penis Erectile Tissue_GSE2457	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.72807
BRD-K51520673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01746
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL-AF4_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6106
K562_Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0329696
NR2F6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00347838
K562_M344_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143367
rhizome	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281423
anaphase-promoting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.632
K562_GSK-LSD1 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129349
yy2_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.20638
trihexyphenidyl-2158	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AKT1_activemutant_9_GDS2304	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.72066
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4700-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K42960858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70436
BRD-K45367466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26812
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48386
BRD-K24312231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18943
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40118
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881044
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151782_6_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.86973
Promyelocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.141
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
BRD-K70969650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57608
Esophageal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.983
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89811208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36298
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91533
Lung squamous cell carcinoma_LUSC_TCGA-77-8009-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-671-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01534
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08193
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40559
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14393
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.63186
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE209601_0_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.54306
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884133
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14812927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58475
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42392619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06733
Chromatin silencing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.713
BRD-K24640918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35098
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06327
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mitotic spindle assembly checkpoint MAD1-MAD2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.619
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82879
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05361
BRD-K21040167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01173
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65636
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4599
CHD1	ENCODE Transcription Factor Targets	1.0	null
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24653
2747_ESYT1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.963706
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24396618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12377
Acute Myeloid Leukemia_LAML_TCGA-AB-2855-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72444
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HCC-15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.59872
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Cerdulatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187367
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00008
MCF7_ENMD-2076_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0240194
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.604
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09632
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884838
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858096
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06732
Polytene chromosome band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.955
e2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_SNS-314 Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0103125
A549	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62621
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.951655
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923407
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27198
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82155
HSF1_KD_GDS1733_753_human_HeLa cells - 4 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.89019
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.185015
Nasopharyngeal carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20523
Plastid thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
Ovary cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.524
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
precentral gyrus, left, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824805
blastomere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30907
17676974-TableS4	GeneSigDB Published Gene Signatures	1.0	null
BRD-K22449045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17698
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BJ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08088
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.158966
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.33953
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
B-CPAP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.61356
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.79866
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.62121
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.827
Nasopharynx epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
OB-06-WW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353072
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838254
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bipolar II disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GINS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.257
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11637
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.26165
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09148
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829233
Liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-WL-A834-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.22474
hsa-miR-451	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20033
2376_DROSHA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.06793
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL1	ENCODE Transcription Factor Targets	1.0	null
NCIH23	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63053
Lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.838
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ZNF518A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE151782_4_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-29b	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
JHU-022 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
Papillary thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
K562_Toremifene Citrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0354985
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.867816
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.505887
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
HN-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.354
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03877
Colo-205 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.341
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81497
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06939
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100316_3_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183271_4_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3	Pathway Commons Protein-Protein Interactions	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.895
OKF-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.579
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ctf18 RFC-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.801
Skin carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
Transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.646
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.66061
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2086
Perturb_8570_KO_Lpar2_SRP220340	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
UACC-257 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52792
BRD-A37056613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38124
Warsaw breakage syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29425
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47283018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08558
BRD-K88573743_A443654_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6724
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55479099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.75328
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.02506
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02524
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LB2518-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_Dasatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119699
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936364
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46313
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mitotic sister chromatid cohesion	GO Biological Process Annotations 2023	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.836207
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-684	GDSC Cell Line Gene Expression Profiles	1.0	2.20888
Colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.537
dacarbazine-2754	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15421
H2AK5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Momelotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0216794
chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.656895
MCF7_Fluorouracil_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0294439
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
Promonocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3537
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31396
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2431
Breast carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
Heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.695
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
double-stranded DNA binding	GO Molecular Function Annotations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19749
vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.581618
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990294
GSE193258,GSE193259_9_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bipolar Disorder	DisGeNET Gene-Disease Associations	1.0	null
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47679
MFM-223	COSMIC Cell Line Gene CNV Profiles	1.0	2.15316
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376637
MCF7_Sodium Phenylbutyrate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133234
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31904
liver	HPA Tissue Gene Expression Profiles	-1.0	-2.05499
hsa-miR-506	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
hsa-miR-548z	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-3135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23819
TAK-875	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67475
BRD-K40332193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29462
FOXJ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29455
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QD-01A-32R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40628462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64414
BRD-K73775927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44133
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Alisertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145645
ATF3	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BV-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transplanted Heart Complication_Myocardial tissue_GSE582	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.13379
decreased body length	IMPC Knockout Mouse Phenotypes	1.0	null
hek293	HPA Cell Line Gene Expression Profiles	1.0	1.6255
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sulfamerazine-3718	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73903
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNW1_02_49	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58686
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
KLF4	ChEA Transcription Factor Targets	1.0	null
DMS114	CCLE Cell Line Gene Expression Profiles	1.0	1.48699
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925488
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
6862_PSMC5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.599496
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.136
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00544
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932992
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3439829__F4	PFOCR Pathway Figure Associations 2024	1.0	null
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.16991
19621087-Table1d	GeneSigDB Published Gene Signatures	1.0	null
BRD-K55399138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17651
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
Bpe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27072
CEBPB	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61440521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82041
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1064
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900458
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.17507
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_M344_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133658
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_131_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262376
GTEX-TML8-0926-SM-4DXSJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934537
PMC11011430__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE196540,GSE196542_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05604
Oral submucous fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
SNU-C5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.97414
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16561
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-FLI1_mod_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_7-Supplementary_Table_7A_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_late-diagnosed_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941253
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65396
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24175
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32018
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.02331
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3451-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Aurora A Inhibitor I_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189513
MYBL2	ENCODE Transcription Factor Targets	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	2.45758
TRIM61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13907
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1541
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917103
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
Perturb_4005_KD_LMNB1_SRP320092	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.28941
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29974
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103122_0_v_1_riok3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-548ac	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00164
K562_Tozasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174006
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7210-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12718
K562_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015625
JVM-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K95035301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4663
Syp1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.620356
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20917
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984269
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53168433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05858
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28627
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.94547
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26978
PMC12706077-44318_2025_598_MOESM21_ESM.xlsx-Dataset_EV19-hKidney_TPP-PISA-Genes_ZNF568	Rummagene Transcription Factor Associations 2026	1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9913
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8614-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.8985
Artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.014
GSE206870,GSE206872_3_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890843
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21033
SIRT6	ENCODE Transcription Factor Targets	1.0	null
K562_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0321453
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17898
KP-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13071
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13454
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0148
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BC-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22063
POR_KO_GDS1678_761_mouse_ILEUM	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06319
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9324_TRPM7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.547541
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95806
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31034
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
Detroit-562 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.442
UM-SCC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
GSE235066_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
methylprednisolone-3183	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PNU-0230031-4288	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78748401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2009
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962093
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53841
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6622
MTA3	ENCODE Transcription Factor Targets	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.21402
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
PSII associated light-harvesting complex II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.508
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10912
PMC12646413-ppat.1013702.s009.pdf-3-KDM2A_KDM2A	Rummagene Transcription Factor Associations 2026	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23926
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18986
pc3	HPA Cell Line Gene Expression Profiles	1.0	0.86408
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2086
MCF7_Lapatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0104952
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54164
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_Divalproex Sodium_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176308
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58301
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.18442
PMC11522423-41598_2024_76982_MOESM1_ESM.pdf-27-THAP9-AS1_THAP9	Rummagene Transcription Factor Associations 2026	1.0	null
liminal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08478
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21874
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075305
ZFP82	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839474
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.710765
BC-06-OP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27887
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46965
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CH-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22969
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
SYK_druginhibition_153_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.9764
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056579
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Euchromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.237
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K59045095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45442
SARS-CoV MA15_Day2-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.96716
NFYA	ENCODE Transcription Factor Targets	1.0	null
t30-blood-rna_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.5592
NHEK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
BRD-K89760040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37301
BRD-K71204648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1583
CRCGN012_HEPG2_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28895
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88428
dorsal terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47068
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82187446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29368
K562_FLLL32_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0248387
Scc2-Scc4 cohesin loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.059
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53797069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03691
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16968
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
SK-N-AS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32144
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EoL-1-cell	GDSC Cell Line Gene Expression Profiles	1.0	1.71984
MDAMB468_BREAST	CCLE Cell Line Proteomics	1.0	2.03814
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76173551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12973
BRD-K90060707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32434
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29817
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
CaSki cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.443
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-475	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67185
oral cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286026
Chlorenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.132
ZBTB33_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54537
BC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.682
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25888
GSE143462_0_v_1_omipalisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32392
HSC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.137
Large cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.192
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865755
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973783
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_SNS-314 Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0258301
BRD-K71368065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30998
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
2313_DNM2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.774816
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910193
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.854187
Oral epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.465
Retinoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.086
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28029
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08706
BRD-K28795679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23435
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256386
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1273d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187442
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91734
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54446
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6427
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459373
MCF7_Givinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0209197
BRD-K98020844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64433
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68935
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4682
A-549 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.537
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K48012250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00672
riluzole-2334	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935088
Primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
BRD-K74919500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16331
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2812
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
adipiodone-3111	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04443
Triglycerides Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
MCF7_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151599
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11568
myc_20940306_e13dot5_erythroblast_purified_from_liver_gof_mouse_gpl6885_gse18558	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.323638
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.82747
mantle zone of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08912
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3922-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Sarcoma_SARC_TCGA-X9-A973-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14169
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96652989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30607
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74354
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rad6-Rad18 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22605
BRD-K22189453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06047
Gastric adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
BRD-K75576005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12444
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70079
DAN-G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMRC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4804
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.959
subiculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34633
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Momelotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162441
WIZ	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K95648552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0105
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.922957
BRD-M53346459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22887
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Chromatin	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CBX2_KO_GDS4445_353_mouse_E11.5 XX embryonic gonads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
A549_Glesatinib(MGCD265)_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190733
SARS-BatSRBD_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.92491
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.906
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16962
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.712
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03877
BRD-K43053725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27287
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48900723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69486
K562_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146841
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07599
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19562
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090361
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Crizotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165765
fetal membrane	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DC-98-HC94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24169
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3607232-mmc3.xlsx-b_RUNX1_SEM_MLLC_H3K4Me3-x_2_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74009
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09297
BRD-A12372458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15583
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Head and neck squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.273
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.27219
Bundle sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.599
BRD-K53971345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2847
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860421
YY1	ChEA Transcription Factor Targets	1.0	null
PFKL_OE_GDS4410_202_human_biceps	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amphotericin B-5404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K88441035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76338
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42923
Monocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916716
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K83049611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28677
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25595
RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.03553
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45856
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24296
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837056
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31486
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SW-48 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
SBC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.32405
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.83979
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC3439829__F4	PFOCR Pathway Figure Associations 2023	1.0	null
c87	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23372
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.52421
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31143
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
nuclear chromosome part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.324576
HCT-116 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00412
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47938
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995652
neural crest	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.554478
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Esophageal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5910_NXF1_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.55457
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880928
Chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Pretectal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28766
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tongue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.23082
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34616
Squamous Cell Carcinoma Of Mouth	DisGeNET Gene-Disease Associations	1.0	null
DNAJB1	Hub Proteins Protein-Protein Interactions	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE114992,GSE114993_9_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus of the optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16334
Human papillomavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15394
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65617
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061098
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WEHI-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
cataract	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-A04231641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44078
u266b1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61G-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
smc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.982
L-methionine sulfoximine-2470	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12951693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46008
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50994
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
head and neck squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120694
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ameloblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
BRD-K60772078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17181
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
A549_Zileuton_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158556
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25405
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6133
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03322
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34279
Bacteremia	DisGeNET Gene-Disease Associations	1.0	null
smc loading complex	GO Cellular Component Annotations 2015	1.0	null
MCF7_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187258
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00883
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Nuclear DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.422
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
scc4	GeneRIF Biological Term Annotations	1.0	null
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Stomach carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K10181552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63338
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31479652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49793
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6396
BRD-K48171978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21977
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35026
Cornelia de Lange syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.902
GSE208254_3_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mitotic sister chromatid cohesion	GO Biological Process Annotations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6021-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44659
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04368
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38435
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1175
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153341_2_v_3_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
embryonic lethality during organogenesis, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.949
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
K562_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152524
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843292
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38749
DU145	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67529
orphenadrine-3801	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMARCA2	Pathway Commons Protein-Protein Interactions	1.0	null
Liver volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
BRD-K30342454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03251
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YI-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87965
Mre11 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.483
GSE150634_1_v_0_cd28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9179018-NIHMS1792335-supplement-Supplementary_Tables.xlsx-ST18-Unnamed_7_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0339957
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15802
Fibrosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
KBG syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mammary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.483
Condensed chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.92
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05128
BRD-K31372389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57028
H3K23ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Osteoclastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.872216
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
telophase	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_2_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03756
SEC61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02483
Lung adenocarcinoma_LUAD_TCGA-69-7980-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_1490_KO_Rpl23a_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.67143
Colonic adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13726
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.48108
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
dicycloverine-4405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK-HEP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H460 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7951
hsa-miR-511	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11363
A549_WP1066_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155335
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SARS-dORF6_24Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.3227
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055723
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28469
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.142579
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02651
BRD-K84710243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27231
A549_Cediranib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134378
MCF7_MK-0752_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138439
htta1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
hsa-miR-4297	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K22087390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14078
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tongue squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.601
SIN3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.368319
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.785
Myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.656
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOTCH1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF280D	Pathway Commons Protein-Protein Interactions	1.0	null
Pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.101
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150555
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07324
K562_MK-5108_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165762
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05596
IZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41775
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841737
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16992
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04731
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNA packaging complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.956
MAP7D3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17271
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46031
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05219
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.10278
TAF7	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899547
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205117
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14712
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22029
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMRC20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48763
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
BRD-K41172555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16532
nterminus	GeneRIF Biological Term Annotations	1.0	null
SKOV-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.37
haloperidol_mus musculus_gpl339_gds2531	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCT-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.493
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.98362
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.1474
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32403948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28504
ZBTB33_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
Oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.671
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.707
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83293
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.33775
Colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.808
Myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.373
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RB1_KD_GSE50532_624_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
K562_Triamcinolone Acetonide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133232
proxyphylline-3115	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mevalolactone-5738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04806
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.35126
ZNF569	Pathway Commons Protein-Protein Interactions	1.0	null
Myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.415
HOS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
B16-F10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.396
Bipolar I disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
hsa-miR-615-3p	MiRTarBase microRNA Targets	1.0	null
hsa-miR-4534	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
cell part	GO Cellular Component Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196699_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31348453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5077
MCF7_Entinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130172
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.751
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSL1	Pathway Commons Protein-Protein Interactions	1.0	null
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27659
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LASV_FML29 _4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.26387
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04997
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59680547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44984
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74988798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64304
BC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.60537
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A44068497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11907
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156283
ZNF649	Pathway Commons Protein-Protein Interactions	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2201
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TIMM50	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-686Ln cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.501
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.9797
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.072
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52485
BRD-K22797212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31245
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244274
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.699653
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966424
rent1_15448691_hela_lof_human_gpl8300_gds705	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.167837
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.09278
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0592
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173810_4_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235066_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.3743
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13803
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14651
MCF7_Celecoxib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0224967
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF585A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07481
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7902-01A-12R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58272
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54882
hsa-miR-1915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Oropharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.849
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26214
BRD-K44212150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22488
Meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.136
hsa-miR-4468	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.160863
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.48545
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30105
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tongue epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.381
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IC-05-AW29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359709
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.611
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHAF1B	Pathway Commons Protein-Protein Interactions	1.0	null
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04604
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
abnormal lens morphology	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
P32-ISH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83457
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_PF-3845_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0209706
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5421
BRD-K11589884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04615
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06115
BRD-K50746465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40616
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948101
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4126
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905478
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.777149
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.30044
NCIH647	CCLE Cell Line Gene CNV Profiles	1.0	1.90791
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-409-ZNF627_ZNF627	Rummagene Transcription Factor Associations 2026	1.0	null
Nasopharyngeal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
8653_TAF12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.583868
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5731
BRD-K43324262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76715
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.904073
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09301
V-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
Mushroom body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26681
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNU-0230031-4757	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
piromidic acid-2996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Retinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
similarity	GeneRIF Biological Term Annotations	1.0	null
K562_Cerdulatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012719
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09045
Transcription factor TFIIH holo complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884133
GSE228181_0_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute promyelocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4083
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.845034
nucleoplasm	GO Cellular Component Annotations 2015	1.0	null
BRD-K05128360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57101
binding	GO Molecular Function Annotations 2015	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K14070721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14596
PMC5967331-41467_2018_4384_MOESM4_ESM.xlsx-Sup_data1_with_CCF_txt-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44079
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55895855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1665
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495714
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910728
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LY-294002-2699	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51134
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1066
CBC412 (AHCTF1)	NURSA Protein Complexes	1.0	null
blastula	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K02299361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12394
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83183
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2556
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836356
nuclear lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ACHN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12004
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76292
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_BMS-754807_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179677
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28608
BRD-K28874552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07897
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Temsirolimus_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145889
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MPP-89	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2777
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0638
HCC4006	CCLE Cell Line Gene CNV Profiles	1.0	1.64972
cornelia de lange syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.00424
MCF7_Pracinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158735
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18064
BRD-K20497425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17266
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26978
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253101
NCIH2023	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52655
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2482
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tongue cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.61352
tongue cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.603295
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
VA-ES-BJ	GDSC Cell Line Gene Expression Profiles	-1.0	-1.73605
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cheek pouch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7357
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pharyngeal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.323
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF829	Pathway Commons Protein-Protein Interactions	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
MCF7_Danusertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138419
cell cycle	GO Biological Process Annotations 2015	1.0	null
TCF21-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02359
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.862889
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871268
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04011
BRD-A55020151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16839
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858096
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gilles de la Tourette syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
PMC9362915-pone.0272017.s004.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary hyperoxaluria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
GSE182888_0_v_1_jmjd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.96066
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19749
SARS-CoV MA15_Day2-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.50058
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GSE215351,GSE215794_7_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCE-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.703
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29M-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36170758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11486
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Keratinocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.019
ZNF324B	Pathway Commons Protein-Protein Interactions	1.0	null
nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.314091
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
BRD-K16432886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23884
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.78273
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289569
Epstein-Barr Virus_Akata BL clone-4hr starve_None_GSE19761	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.50072
EFO-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48747
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OE-33 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
BRD-K77246148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39055
Fanconi anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
benzocaine-4224	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04079
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35392
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27274
MCF7_Linifanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136509
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32478
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.29284
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
A549_Linifanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0251943
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01544
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35795
Pancreatic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.538
BRD-K89584810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02672
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nuclear DNA replication factor C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
K562_Cimetidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179318
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870389
Submandibular gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
NR2F2	ENCODE Transcription Factor Targets	1.0	null
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42716
GSE171572_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
MPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12519
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations	1.0	0.346786
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-C-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34942
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prothylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-38-KX20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243675
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08256
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04638
GSE214685_0_v_1_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
liminal part of the r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37019
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.740299
TONSL	Pathway Commons Protein-Protein Interactions	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FC-64-QJ96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204118
DNA replication factor C core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.962
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Zileuton_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0259048
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870678
A549_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0207157
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14452
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393896
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QH-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205788_0_v_1_gfap_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4521181-oncsis201520x8.pdf-29-TBX18_TBX18	Rummagene Transcription Factor Associations 2026	1.0	null
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14529
K562_Meprednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0230146
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
Ovary epithelial cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94125
Lung fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.346
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43924
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08582
TCF3	ENCODE Transcription Factor Targets	1.0	null
chr19_19285013_G_A_b38	GTEx eQTL 2025	1.0	1.39891
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
weak	GeneRIF Biological Term Annotations	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
PRR14	Pathway Commons Protein-Protein Interactions	1.0	null
Calu-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.7694
Oral squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.282
Lung squamous cell carcinoma_LUSC_TCGA-60-2719-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	0.935995
hsa-miR-124	TargetScan Predicted Conserved microRNA Targets	1.0	0.002088
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17952126-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Alcoholic liver cirrhosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.454
hsa-miR-384	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24009
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.887
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rett Syndrome_frontal cortex_GSE6955	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.51748
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2964
ZNF682	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03571
Pulp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.752
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297263
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11637
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14804
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00464
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18078
absent pinna reflex	IMPC Knockout Mouse Phenotypes	1.0	null
tinidazole-4370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
estradiol_homo sapiens_gpl570_gse5102	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Type I site-specific deoxyribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K47504528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06953
ZNF747	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.923315
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.823
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13311
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.935995
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
CBF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.607
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESR1	ENCODE Transcription Factor Targets	1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29259
Gastric	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.898633
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89922
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83358
Cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_34_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4841
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52108
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33216
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39769
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19896
BRD-K25907192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52865
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30517
Colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.787
clemizole-7371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85635
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.538
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-Ale_DE_MSC_genes_H_sapiens_340_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SMARCC2	ENCODE Transcription Factor Targets	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
naringenin-4597	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
1774_COPG1_P1	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.06361
Fibrosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
BRD-K36422663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12798
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63448
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05182
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DNA gyrase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.408
hsa-miR-3197	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20662
A549_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013372
SMARCA4	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.952831
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5323-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887765
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.227041
SIN3B	ChEA Transcription Factor Targets	1.0	null
BRD-K16207499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90961
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306444
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997322
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAL-33 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.316
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.748
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_AMG-900_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175223
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.17815
BRD-K11757577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96382
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K44497547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79639
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21475
Nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0502
A549_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143276
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.438776
MCF7_PJ34_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016853
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45138
PMC10897204__F6	PFOCR Pathway Figure Associations 2024	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323558
SCC-25 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.726
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
BTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03849
RUNX2	ChEA Transcription Factor Targets	1.0	null
b10411	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
BBC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01369
EHMT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33909
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910085
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.674
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56336
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16457
CTCFL	ENCODE Transcription Factor Targets	1.0	null
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881915
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826454
BRD-K21713052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16831
Tca-8113 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
NCIH2052_PLEURA	CCLE Cell Line Proteomics	1.0	2.58771
COMA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.233
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23468
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16334
BRD-K57734337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66959
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976079
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52289
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.863432
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5645
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19773
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3PZ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CENP-T-W-S-X complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
cell cycle process	GO Biological Process Annotations 2015	1.0	null
Uterine sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
TRIM21	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K18493795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97443
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
White blood cell count (basophil)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
BRD-K21253219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08397
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MGST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04603
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36848
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.23003
Hypopharyngeal carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.444
hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07937
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09947
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
SEMA3G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589393
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24712
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13042
Lung adenocarcinoma_LUAD_TCGA-93-A4JO-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Resminostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150048
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6187
KYSE450	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59296
K562_UNC0379_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180332
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053225
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881899
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.086
K562_Alendronate sodium trihydrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0306421
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.435376
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39598
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063541
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.586
SIN3A-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
KAT2B	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42709
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75648723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10164
Mitotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.243
Perturb_5183_KD_Ssrp1_SRP094584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41146
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28883
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.35775
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29327
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
K562_UNC0631_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158279
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1027_KO_Ovgp1_SRP379795	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.31483
Brain cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.458
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997322
RMUGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55872
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13523
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFB2_KD_GDS4483_351_mouse_Embryonic palatal tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.92088
Gingival cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8327
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHLF	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.98314
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46503
LRIF1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54236126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18771
K562_Costunolide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150511
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_MLN8054_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016828
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0161
MCF7_S3I-201_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019516
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Synapsis initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.787
BC-25-VR48_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277861
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2259
F36P	CCLE Cell Line Gene CNV Profiles	1.0	1.93182
Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Scc2-Scc4 cohesin loading complex	GO Cellular Component Annotations 2025	1.0	null
NCI-H2081	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.781287
K562_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166123
BRD-K87385385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50311
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983299
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57417
SP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15251
BRD-K25045770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74784
A-375 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
diphenylpyraline-4299	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019849
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LNCAP	BioGPS Cell Line Gene Expression Profiles	1.0	0.928545
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.50229
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CYFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09792
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360654
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Oral squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.924
Megakaryoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endometrial cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
BRD-K55237592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02967
CCRF-CEM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
hsa-miR-4478	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MCF7_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0100499
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930556
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.703906
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K52049165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27165
K562_Barasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0251293
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89214
NCIH2029	CCLE Cell Line Gene Expression Profiles	1.0	1.89057
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HSC-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.388
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11767
MCF7_S-Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142592
Monopolin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.401
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27263
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-87-OG75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204562
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05832
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8958
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161293
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42497
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09411
MYC-22102868-BL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846983
K562_MLN8054_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0197522
18593951-TableS3	GeneSigDB Published Gene Signatures	1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.903369
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.524
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87653
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.2398
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1464
Lip And Oral Cavity Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966295
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.843789
TTYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64705
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214833
HUH7	CCLE Cell Line Gene CNV Profiles	1.0	1.66806
Smc5-Smc6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.963
GSE223334_1_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Fulvestrant_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159595
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23011
GSE112995,GSE132079_1_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
M1 melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
BRD-K08971733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77197
DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.434
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07537
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862722
Carcinoma, Basal Cell	DisGeNET Gene-Disease Associations	1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43095
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Tozasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119283
BRD-K04257723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26349
organelle part	GO Cellular Component Annotations 2015	1.0	null
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05473
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14391
8842_TFCP2L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.647411
VDR	ChEA Transcription Factor Targets	1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE145311_1_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55448
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27477764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05435
hsa-miR-3929	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.952511
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB33_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37334
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A172_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	10.7267
DU-4475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26579
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.03433
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35147
SENP7	Pathway Commons Protein-Protein Interactions	1.0	null
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12231
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5443-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05411364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17293
163 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61654
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7603
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.01552
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_GSK1070916_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150258
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935288
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.511846
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997322
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.45706
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_AICAR_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202951
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43179
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.472
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24514314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01042
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3749
MiaPaCa-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.349
Pancreatic ductal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65986
RNA polymerase II, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.339
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884133
BRD-K51972131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86454
RPP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27223
HLF	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92276
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DC-13-RZ62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246416
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RR-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitotic Telophase/Cytokinesis	Reactome Pathways 2024	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
SCC-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
MCF7_Valproic acid sodium salt_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150031
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14708
A549_Ofloxacin_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136115
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879608
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SCAI	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K24125966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43888
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23432
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920831
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver cirrhosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.928
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATR_knockdown_120_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.77836
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22061
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833064
MCF7_BMS-754807_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135192
A549_Temsirolimus_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172873
protein complex	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.561
A549_Azacitidine_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.00829298
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.47835
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF462	Pathway Commons Protein-Protein Interactions	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047374
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26248
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26124
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16992
HHV8_72Hour-BEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.1965
BRD-K59191599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31267
BRD-K50851442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16444
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960311
MCF7_MK-0752_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200155
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1972	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.844437
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05706
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34501
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23579
Oral cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.269
Renal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
KATOIII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.642
BRD-K13320013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09004
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921939
BRD-K37741838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00139
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40347
PMC12824906-mmc5.xlsx-Sheet1-Table_S4_Target_genes_of_FOXM1_and_their_expression_across_the_subtype_of_breast_tumors_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13969
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.81
superficial stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32574
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83616
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877565
IPO8	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.423
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.16678
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LCLC-103H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.47403
Plant parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.965
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926686
Nasopharynx carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
FBXO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20286
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06302
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
FOXM1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
meclocycline-3277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00513
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311815
Salivary gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30971
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20575
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.00635
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
BRD-K34343777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22905
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42109
r9ab	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.918
BRD-K65887908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32021
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11761
KB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.66
A549	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75159
BRD-A92357389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38912
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K61087440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70877
BRD-K68562280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07809
BRD-K28105726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02426
BRD-A98888138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3425
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18165
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K83270266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44488
BRD-K09487932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2648
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897082
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CENP-A containing chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
DNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.252
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
A549_MC1568_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125167
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.979
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27393
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.847841
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.731582
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4446-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CAL-62	GDSC Cell Line Gene Expression Profiles	1.0	1.59894
BRD-K01225247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27691
A549_Sodium Phenylbutyrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146013
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.937458
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41906
BRD-K07588901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36892
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02429
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55975
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.292
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981293
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35963
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52776
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.078298
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.826679
Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
nucleus	GO Cellular Component Annotations 2025	1.0	null
K562_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0222056
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.948
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23171
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7989
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07501194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09573
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79276
Buccal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.643
NABP1	Hub Proteins Protein-Protein Interactions	1.0	null
MDA-MB-361 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.11736
CAL-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.49
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypercalcemia	DisGeNET Gene-Disease Associations	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_PD173074_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162905
vertebral transformation	IMPC Knockout Mouse Phenotypes	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57347
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF552	Pathway Commons Protein-Protein Interactions	1.0	null
E2F1-21310950-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
K562_Glesatinib(MGCD265)_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0265258
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
seminal vesicle	HPA Tissue Protein Expression Profiles	1.0	0.935995
BRD-K97487406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55274
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13814
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32059
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastric cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
K562_CEP-33779_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157646
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
required	GeneRIF Biological Term Annotations	1.0	null
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.46533
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37283718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0805
FOXP2	ENCODE Transcription Factor Targets	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
guanfacine-5256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ETS1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70171
SREBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828324
KDM5B	ChEA Transcription Factor Targets	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03164
BRD-K32760954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39362
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
RHOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15957
BCL3	ENCODE Transcription Factor Targets	1.0	null
GSE144231_6_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26978
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K39419290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25268
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mammary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.485
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42137
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.11726
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
colo680n	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.885112
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16744
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87427
BRD-A05828965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27835
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01315
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952932
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64103
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
1578_CHML_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.661517
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	3.65491
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_BMS-911543_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01455
Autosomal dominant intellectual developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
BRD-K75807882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67115
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K27971671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.363
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66828
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147240_3_v_4_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
a431	HPA Cell Line Gene Expression Profiles	-1.0	-0.924827
K562_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0252246
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72793
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BGC-823 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
STAT3	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13130949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04466
Tachycardia_Myocardial tissue_GSE7999	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.54054
BRD-K75976016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18626
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05246
K562_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0306038
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18745
Chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.254
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.062
GSE127916_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF45	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-MF-A522-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.707
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01719
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.663555
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44795
SREBF1	ENCODE Transcription Factor Targets	1.0	null
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14953
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.995
Bipolar disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.086
PPP2R5A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832829
15546871-Table1S	GeneSigDB Published Gene Signatures	1.0	null
PMC9362915-pone.0272017.s003.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20034
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31649
Peripheral nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.0
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.221
SUP-T1	GDSC Cell Line Gene Expression Profiles	1.0	2.04723
BB-20-UU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258547
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4757
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_9280_KD_DDX24_SRP153815	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.0265
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE151160_0_v_1_cd36_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51932
BRD-K49443464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90222
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CPCN	CCLE Cell Line Gene Expression Profiles	1.0	1.82164
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13568
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04323
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833835
maintenance of mitotic sister chromatid cohesion	GO Biological Process Annotations 2025	1.0	null
Urinary bladder transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.945449
BRD-K63111122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59216
NIPBL	Pathway Commons Protein-Protein Interactions	1.0	null
Cell Cycle, Mitotic	Reactome Pathways 2024	1.0	null
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45002
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883359
A549_PFI-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014486
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Tofacitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016504
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59476
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ts/a	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1142
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nt2d1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
MCF7_Meprednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132062
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_THAP11_20581084	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61501
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8566
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4306	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Cell Cycle	Reactome Pathways 2024	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.846486
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Glioblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914391
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17282
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56739
K562_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0244592
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18217
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06748
BRD-K05074020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18213
GSE223008_6_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32468
skmel24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
PMC12254212-42003_2025_8449_MOESM5_ESM.xlsx-Overlap_of_AR_interactomes-Proteins_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23371
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
NHBE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
Multiple myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4398
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43775480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01978
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Osteosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.339
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JHOC5	CCLE Cell Line Gene Expression Profiles	-1.0	-3.29488
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM13	CCLE Cell Line Gene Expression Profiles	1.0	1.97183
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31524
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74239
MCF7_Tubastatin A HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169036
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35481
clemizole-3672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10981
Hs-578T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11295044-pnas.2403331121.sapp.pdf-134-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222754
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.171673
POU5F1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cbp_cpb heterozygous mice_GSE30880_328_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
g2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.349
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37624
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_TGX-221_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146971
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883007
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51143
BRD-K29178949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41154
NFATC1	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CG-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RB1_KD_GSE50532_656_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Podocyte foot	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
ATM_knockdown_113_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.66333
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45896
pre-primosome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.336
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2012
ZNF195	Pathway Commons Protein-Protein Interactions	1.0	null
K562_JQ1_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153489
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64899
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K94858557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77158
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41674016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01774
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thoracic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Mercaptopurine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018844
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01378
GSE241875_1_v_0_huwe1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5741
Prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.718
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35796
Retinal cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3417
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83037
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6015
MCF7_Capecitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0278855
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11232677__F7	PFOCR Pathway Figure Associations 2024	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.18565
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HU-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Maraviroc_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0280807
BRD-K36135420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29069
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05409
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64108
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14703
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394128
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23889
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.653127
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.88699
BRD-K92803674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2534
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cohesin Loading onto Chromatin	Reactome Pathways 2024	1.0	null
A549_JNJ-7706621_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015087
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61458
Cohesin Loading onto Chromatin	Reactome Pathways 2014	1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18698
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922759
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
eldeline-3831	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
Dental plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847861
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01094
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26383
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05235
CREB1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6406-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIS12	Pathway Commons Protein-Protein Interactions	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43924
Spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053153
Skin cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.646
mitotic cell cycle	GO Biological Process Annotations 2015	1.0	null
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27256
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-899 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37604
MCF7_Ki8751_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166244
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5442-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
terbutaline-5764	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
K562_Linifanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157216
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4335
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920831
GSE104508_0_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Larynx squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.531
BRD-K26461918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20445
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA2_02_28	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62814
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4332_KDSR_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.567301
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85696
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.389
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Motesanib Diphosphate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143795
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.874605
Dosage compensation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920099
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00915
Oral epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.424
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
result	GeneRIF Biological Term Annotations	1.0	null
Gingival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.677
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56253099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33338
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186963
ovary_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.25458
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.885507
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orlistat-6420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AHDC1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83935370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54181
OE-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
L363	CCLE Cell Line Gene Expression Profiles	1.0	2.6772
Chronic myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
MCF7_UNC1999_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0242443
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JB-60-JM38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233879
CCSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75212
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
PMC10280803-1415-4757-GMB-46-2-e20220358-s3.pdf-7003-NR1D2_NR1D2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84143716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03793
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE103297_1_v_0_glis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10851
CCNDBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34716
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916202
BRD-K20051655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81918
TAF7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dms53	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44273
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.2554
GATA3	ENCODE Transcription Factor Targets	1.0	null
Nicotine addiction_Ganglioneuroblastoma_GSE11208	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.96175
FD-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.539
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.70713
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
Colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.777
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18523
MCF7_Resveratrol_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015262
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67199
STAT5A	ENCODE Transcription Factor Targets	1.0	null
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79566
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1567
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.855
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Trichostatin A_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185744
Phosphatidylinositol 3-kinase complex, class IA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
RAD21	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Body fat distribution (trunk fat ratio)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38222
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.824922
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22615
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_PHA-680632_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140156
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.52605
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16347
spleen	HPA Tissue Gene Expression Profiles	1.0	1.16267
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
K562_Sodium Phenylbutyrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145476
CHAF1A	Pathway Commons Protein-Protein Interactions	1.0	null
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95806
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920831
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03877
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Box H/ACA RNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
c4i	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
NCIH2405	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61078
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07395
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.7992
ELF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RPL26	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K51322795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25807
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05908
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33031
16813654-SuppFile2	GeneSigDB Published Gene Signatures	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12486
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CBX1	Pathway Commons Protein-Protein Interactions	1.0	null
NHK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34955
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Body fat distribution (leg fat ratio)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CE-95-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415105
BRD-K44177822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10216
A549_Divalproex Sodium_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179869
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32948
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244172
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SAOS-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21881
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC11699082-BLOODA_ADV-2023-012291-mmc1.xlsx-Sheet1-CD37_pos_corr_top100_GSE10846_CHOP_GCB_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87199
SK-MES-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
Brain Lower Grade Glioma_LGG_TCGA-DU-6396-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatitis C infection_Hepatocyte_GSE2067	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.40303
4953_MED30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.528057
PMC10280803-1415-4757-GMB-46-2-e20220358-s3.pdf-7003-ENSG00000174738_NR1D2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4261	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.697976
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ovarian disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902637
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22931
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.707314
hsa-miR-502-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56036
hydrocortisone-6684	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Outer kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.858
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Familial isolated trichomegaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
MCF7_CYC116_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187536
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4066
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19749
HDAC2	ENCODE Transcription Factor Targets	1.0	null
PANC0403	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91032
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69472
Multiple Chronic Conditions	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-1226	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X4-01A-51R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF724P	Pathway Commons Protein-Protein Interactions	1.0	null
K562_PD98059_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176129
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11433
PMC10248509-Data_Sheet_5.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
chromatin	GO Cellular Component Annotations 2015	1.0	null
BRD-K40220562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07136
Lung adenocarcinoma_LUAD_TCGA-62-A472-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.13088
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35433
KLN205 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08068
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEx AdiposeTissue 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	12.278
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ELF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P31FUJ	CCLE Cell Line Gene Expression Profiles	1.0	1.74812
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34904
nuclear part	GO Cellular Component Annotations 2015	1.0	null
psn1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
Serum metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
BRD-K01643633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21338
TAL1	ENCODE Transcription Factor Targets	1.0	null
ZNF302	Pathway Commons Protein-Protein Interactions	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946836
H3K23ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pharynx squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45248
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
MG-63 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
Perturb_17044_KD_IRF4_SRP201887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.872
BRD-K21660570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02728
BRD-K12115687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50374
CENP-A containing nucleosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.047
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.88152
DNA replication factor C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
H3K79me2_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS-114	GDSC Cell Line Gene Expression Profiles	1.0	1.94867
LinE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8350-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
R-atenolol-2496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.206913
Lung squamous cell carcinoma_LUSC_TCGA-39-5035-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72793
RFX5	ENCODE Transcription Factor Targets	1.0	null
SK-BR-3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
trastuzumab_homo sapiens_gpl570_gse15043	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tiotropium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5183
Breast cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
BRD-K73573090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20101
MCF7_Alvespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113931
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917083
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0375
K562_Temsirolimus_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163099
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.76814
hel12469	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30385
BRD-K83690550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35626
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.90432
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
MCF7_Roscovitine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0207912
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929467
ChaGo-K-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05578
MAFK	ENCODE Transcription Factor Targets	1.0	null
BRD-K91180296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21378
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44285
BRD-K53388755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02159
GB-73-QS80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257008
TE-11	GDSC Cell Line Gene Expression Profiles	-1.0	-3.53328
9686_UTP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.07163
BRD-K15259307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00796
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
Nasal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.525
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20858
K562_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147782
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06084
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.38883
BRD-K39809702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12835
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910279
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8892
NCI-H522 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.44228
BRD-K10634221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49137
8305C	CCLE Cell Line Gene CNV Profiles	1.0	1.64031
PLCPRF5	CCLE Cell Line Gene CNV Profiles	1.0	2.90237
member	GeneRIF Biological Term Annotations	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.57648
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01551
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
HD-29-LW24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331746
SP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24197
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246501
Head and neck squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.46
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43805
Transcription factor TFIIK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
SUV39H1	Pathway Commons Protein-Protein Interactions	1.0	null
pre-replicative complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.908
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30515
SRF	ENCODE Transcription Factor Targets	1.0	null
gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846396
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09133
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05014
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6959
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.3641
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
AGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30436
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	0.913324
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04871
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
interphase	GeneRIF Biological Term Annotations	1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04869
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05206
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.730388
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00457
Bundle sheath cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.328
Skin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
SCH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K02087489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77537
A549_Ki16425_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163803
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81318113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39476
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SiHa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.545
MCF7_Selisistat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0199085
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.99441
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22729
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K25649458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18477
BRD-A38066207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2426
Linear element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
hsa-miR-4496	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE179138_4_v_1_lama4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8396
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.793872
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MCF7_M344_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130696
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Busulfan_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153052
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.985
Mediator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.414
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81501934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40057
Cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UM-SCC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.843
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4173
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00494
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98965
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955796
ZFX	ChEA Transcription Factor Targets	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860541
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PSMG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3094
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
KAT2A	ENCODE Transcription Factor Targets	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-USF2_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01288
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10986
SK-MEL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.163
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56405
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16141
Lipid storage disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_PF-573228_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212375
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.976989
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K90741031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26374
K562_MK-0752_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175508
Low Density Lipoprotein Cholesterol Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25714
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14282
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A39506880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75256
Microsporidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.858642
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LoVo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
SYK_druginhibition_152_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.5804
A549_Tie2 kinase inhibitor_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152061
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tongue carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.208
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877689
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
SIN3A-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.755
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8255
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Coffin-Siris syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
MCF7_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143026
PMC6996923-elife-46981-supp4.xlsx-KO_Up_Only_Vs_OCT4-Column_ID_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.12779
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.052
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64968
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MM-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52506
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02476
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0222446
BRD-K73296174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61067
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922616
Metaphase plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.325
MCF7_Rigosertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120285
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP-4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889934
GSE112860_5_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.119
JUN	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
amiodarone-4657	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63958
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.975315
Apoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.868
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nonsyndromic cleft palate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
NCI-H1975 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210758
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Isw1a complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1343	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Extrachromosomal circular DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.544
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
Ovary adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.482
Perturb_14656_KD_LINC00673_SRP102315	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
tongue cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.608124
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07613
NB-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.15399
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11761
ZBTB16-27035670-HESC-HUMAN-ENDOMETRIAL	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83186
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062731
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKG-IIIa	GDSC Cell Line Gene Expression Profiles	-1.0	-2.22836
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04921
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65575
RNF2_02_68	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59588
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1794
Intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91773
AA92593	DeepCoverMOA Drug Mechanisms of Action	1.0	0.79
Ca9-22 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
santonin-4353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.086
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.54688
A549_Iniparib_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0194425
PMC10866659-jci-134-176311-s178.xlsx-S3_TurboID_vs_RUNX1-RUNX1T1-gene_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC9386181-Table5.XLSX-BFT-Unnamed_1_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06320746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44871
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gall bladder cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
CFPAC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19749
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01657
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37775
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0753
GSE119564_2_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEp-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.399
BRD-K44430448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04862
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3680531-cc-12-1510-s02.pdf-27-SP100_SP100	Rummagene Transcription Factor Associations 2026	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.945103
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.910404
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128408
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343681
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.32502
PMC3728595-srep02327-s1.pdf-17-POU2F2_POU2F2	Rummagene Transcription Factor Associations 2026	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
HT-29 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.582
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74371
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-EZ-7264-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tanespimycin-6184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BEN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.851283
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
ZNF688	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09696
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13952
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62335
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68834
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914702
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.722464
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23256
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829577
A549_Barasertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150658
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87653
CAF-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27068
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63815
BRD-K07431402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68174
PMC9174176-41467_2022_30924_MOESM6_ESM.xlsx-OC3-SYMBOL_ONECUT3	Rummagene Transcription Factor Associations 2026	1.0	null
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46743
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.59
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14203
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67982
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.935201
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67405
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_JNJ-26854165_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0330484
thalidomide-606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.23955
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KAT2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2123
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94Y-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
HA-30-KD77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.515519
K562_NVP-BSK805 2HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196154
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10931
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07932
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.76704
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55977
TRIM28	ChEA Transcription Factor Targets	1.0	null
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.7
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10334
harman-4408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPA2	Hub Proteins Protein-Protein Interactions	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
novobiocin-435	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16566
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
K562_Andarine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.022516
Sarcoma_SARC_TCGA-3B-A9HR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2373
HT	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21992
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35288
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37949
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Condensin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.487
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ceritinib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.52
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47874568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52989
1197_CARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.607138
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25092
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59861
Urinary bladder cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.365
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LM4_M2	MotifMap Predicted Transcription Factor Targets	1.0	null
LS-174T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56188108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17905
hsa-miR-1537	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Uterine cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
estradiol-6718	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055743
Gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.542
hsa-miR-4644	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995547
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864453
Ovarian carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
BRD-K22839533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26807
BRD-K33705415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32543
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01971
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
mitochondrion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.182122
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69225
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855381
BRD-K23481525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02486
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62634
BRD-K86019347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54774
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27868
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.935995
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885532
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
tolmetin-4167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44882
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60514
nibpl	GeneRIF Biological Term Annotations	1.0	null
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21435
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.728152
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.31575
oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.58437
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.81168
MCF7_Azacitidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158555
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Z-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE242290_1_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K62504352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42995
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33086
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.227041
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.634
HN-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
CCDC88C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42105
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87028
BRD-K39573478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5211
K562_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156932
PFDN1	Hub Proteins Protein-Protein Interactions	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8235
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07932
Laryngeal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
K562_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163587
orphenadrine-4359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_Sodium Phenylbutyrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137621
Oral mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.486
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151782_2_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47946
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DNA replication preinitiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.298
BRD-K45563993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01979
Complex laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32968
WM-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mad-Max complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
carbinoxamine-2725	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	1.0	1.41117
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.724436
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32435
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8689
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38039
TC-YIK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884133
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47199
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48005
metixene-2451	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Isw1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.293
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232545
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
K562_Curcumin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150296
BRD-K57242481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38859
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40851366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13065
hsa-miR-4419b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.81912
Kmp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
cohesin loader activity	GO Molecular Function Annotations 2025	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Spindle microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.307
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1036
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33947
Scc2-Scc4 cohesin loading complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09618
BRD-K93457574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35413
C6 glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
K562_Dacinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138555
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Calu-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.17857
H3K27ac_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01262
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.74009
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15271
T-47D cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.297
MCF-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.936
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22404
beta-escin-6050	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39435
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05231
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872416
Hypopharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.821
Stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.345
BRD-K11573765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28226
squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079701
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00598
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R3-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
ZFP1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Storage tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.625465
IZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42177
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Laryngeal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
ELK1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924205
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80474
budesonide-2866	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T-98G cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
Rectum adenocarcinoma_READ_TCGA-EI-6883-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46763
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201524
Oropharyngeal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.72
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06131
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864537
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
MCF7_SRT2104_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162819
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.334315
9841_WDR75_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.20056
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_AG-14361_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144306
BRD-K46877890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13584
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38949
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46232
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55119
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49307935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21014
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	1.05587
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09393
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37516
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77392
SK-BR-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25202
Roberts syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.303
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74465
BRD-K25979847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14468
6794_PRPF38A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.504175
Melanoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.529
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34843
Esophageal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
BRD-K82793574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66225
BRD-K62909976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11239
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3216
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.666
hsa-miR-762	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
protein n-terminus binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4436a	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
ACTL6A	Pathway Commons Protein-Protein Interactions	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.527944
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46451
DNA binding	GO Molecular Function Annotations 2023	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13129
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_JNJ-7706621_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153759
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J2-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.30486
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32027
BRD-K73808079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67087
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21427
GSE173810_4_v_6_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
K562_Tanespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0343126
FOSL1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70926
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.651
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.118337
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11117
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86845405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59933
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20821
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950564
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34882
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6467-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_BRD4770_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140965
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UM-SCC-14A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54983
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29293
UBTF	ENCODE Transcription Factor Targets	1.0	null
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC0327	CCLE Cell Line Gene CNV Profiles	1.0	1.40507
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836178
A549_Linifanib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0127903
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K64660038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10156
K562_CUDC-907_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170854
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.843242
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.74703
Rubinstein-Taybi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48239
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03994
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.857231
MCF7_FLLL32_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151711
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150506
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
M Phase	Reactome Pathways 2014	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859211
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_EED226_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161404
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25116
SCC-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.324
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77054
Late recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2764
C-33A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_6-Supplementary_Table_6A_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_Childhood_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20388
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121146
Rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.786
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847977
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40129
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151782_3_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.06191
ZNF264	Pathway Commons Protein-Protein Interactions	1.0	null
SERPINE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610388
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1758
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91705
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.33539
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.161
U-87MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.22998
chromosomal part	GO Cellular Component Annotations 2015	1.0	null
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Iniparib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129932
MCF7_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200325
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09133
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF625	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K58268854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07292
K562_Glesatinib(MGCD265)_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190897
nizatidine-3047	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell Cycle, Mitotic	Reactome Pathways 2014	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258774
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Buccal mucosa cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.911
Nuclear cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.351
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54809
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052192
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04339
MECO complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
maintenance of mitotic sister chromatid cohesion	GO Biological Process Annotations 2023	1.0	null
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-231 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.806
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51597
BRD-K05119275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57326
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57697
UM-SCC-22A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.913884
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Serum Ldl Cholesterol Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
MCF7_Roscovitine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151573
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pericentric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87927290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70129
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7933_KD_Spt6_SRP132004	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.64314
PPARD	ChEA Transcription Factor Targets	1.0	null
markedly	GeneRIF Biological Term Annotations	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883007
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.38178
SIN3A	ChEA Transcription Factor Targets	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20271299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27297
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20705
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.935995
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52393
Cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.287
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.946625
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3189923-pone.0025991.s001.xlsx-CENPB-Unnamed_1_CENPB	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COASY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1424
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K59437706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0477
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cohesin	GeneRIF Biological Term Annotations	1.0	null
M cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.641989
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03009
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01851
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48567
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.82131
MG63	CCLE Cell Line Gene Expression Profiles	1.0	1.36808
FOXM1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.957733
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.875624
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MT-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
Super elongation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.166
SW962	GDSC Cell Line Gene Expression Profiles	-1.0	-1.69388
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.983
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8825
Oral cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.091
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.89712
BRD-K91191855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28392
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.60737
ludlu1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
hsa-miR-641	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082771
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837207
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
J-82 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
CRCGN009_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02681
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3056
BRD-K06926365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02819
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_PF-3845_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156445
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_NOT_Autophagy_NOT_GSE22255_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
smc loading complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPI-2589-1 (RPA1)	NURSA Protein Complexes	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14051
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883007
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858096
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QZ-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polytene chromosome interband	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.654
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6511
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3591
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Micronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.57714
SIX5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39400123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32746
meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08413
K562_Triamcinolone Acetonide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0230189
A549_Ellagic acid_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160114
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883007
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40610042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49989
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262745
hsa-miR-3175	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76919
smc loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.60534
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09993756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12688
BRD-K06219419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77431
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15802
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AURKB	Pathway Commons Protein-Protein Interactions	1.0	null
isocarboxazid-4706	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF8	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95605
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16345
Perturb_7608_KD_YY1_SRP237753	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.50364
CAKI2_KIDNEY	CCLE Cell Line Proteomics	1.0	6.20722
MCF7_JNJ-7706621_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159302
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32831
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43797
cellular_component	GO Cellular Component Annotations 2015	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reticular formation of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19978
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HEC50B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51215
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIF18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3615
PFKL_OE_GDS4410_75_human_Biceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K85359206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21067
Cell cycle	KEGG Pathways 2026	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2431
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08263
A549_ENMD-2076_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0254488
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13807_KD_Qki_SRP116547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.09021
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.739
A-431 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.927588
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.952227
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874616
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943309
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73159
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z2-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934588
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
pm85	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
MCF7_AMG-900_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184132
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20516
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28394
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872411
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-29a	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20133
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4014
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.03122
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01398
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73408
ZR-75-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
RSC-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.156
NCIH1793	CCLE Cell Line Gene CNV Profiles	1.0	2.17022
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59937
K562_A-366_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202209
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26511
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66853
GTF2B	ENCODE Transcription Factor Targets	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LA-44-KW22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219156
K562_Lomustine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177639
Oral squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.334
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.16727
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07577
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883007
Oropharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K33217094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24049
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0229982
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JI-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	130.816
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1585
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056278
CENP-A recruiting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.753
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50115
MCF7_WHI-P154_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185237
Tongue cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.925
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ECC10	CCLE Cell Line Gene Expression Profiles	1.0	1.36085
MCF7_BMS-265246_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148682
A549_PF-573228_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013888
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03363
A549_Azacitidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154215
hsa-miR-4757-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K66189308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80216
6740_PREB_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.0855
Lung adenocarcinoma_LUAD_TCGA-50-5946-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Metabolic dysfunction-associated steatotic liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.062
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K35193502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57827
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270603
INCENP	Pathway Commons Protein-Protein Interactions	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
RPMI-2650 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.525
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DSN1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19732
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21389
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.66615
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858096
BRD-K73275682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01018
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WiDr cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63983
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25442
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
metacetamol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4734
SUZ12	Pathway Commons Protein-Protein Interactions	1.0	null
Laryngeal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
KB-V1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03845
BRD-K38558166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33489
absent pinna reflex	MGI Mouse Phenotype Associations 2023	1.0	null
Chronic atrial and intestinal dysrhythmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
POS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
BRD-K32451879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07843
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13365
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9114
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887221
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39322
BRD-K36539857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13648
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.829
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.65848
AGS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TIA1_KO_GSE54418_267_mouse_spinal cord	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
dorsal part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72181
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15802
beta-escin-4364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
BRD-K43834805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26674
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11586
Tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.89
primidone-3402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WF-85-JN16_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268604
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.634
Hypertrophy	CTD Gene-Disease Associations	1.0	1.01286
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal lens morphology	IMPC Knockout Mouse Phenotypes	1.0	null
mantle zone of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96215
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UCHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06475
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10361
Female reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.361
GSE126463_4_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31034
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
BRD-A61778798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18832
HaCaT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.385
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.894759
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50502
ACCMESO1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00985
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34369
Transcription factor TFIIIC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.016
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Tazemetostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200457
GTEX-QDT8-2526-SM-48TYX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839603
BRD-K51858914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04276
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43721
NCI-H661	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48014
nefopam-3627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
peripheral nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BL6780 (NIPBL)	NURSA Protein Complexes	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09664
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28521
hydrastinine-5494	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912868
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63595
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_ENMD-2076 L-Tartaric acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172685
Blood Basophil Count (Lab Test)	DisGeNET Gene-Phenotype Associations	1.0	null
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30772
Bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
A549_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127792
GSE154464_0_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63573625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46987
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9375	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.88299
ZNF585B	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0208789
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120184
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
colo704	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01692
PPP2R5E	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Mocetinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173033
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904356
H2810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
4953_MED30_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.00415
MCF7_Cerdulatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187992
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08239
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K47577519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63293
Lung squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34259
BRD-A71722688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01311
hsa-miR-370	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.13628
POU5F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.711022
NHOK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.491
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81529
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE218060_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K53443314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74918
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193993_1_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null