association	dataset	threshold value	standardized value
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855541
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31183
LB373-MEL-D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE209698_2_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
8305C	DepMap CRISPR Gene Dependency	1.0	2.37375
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CG-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133516_0_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mhc class i protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.211587
hsa-miR-3976	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PK8	DepMap CRISPR Gene Dependency	1.0	3.76883
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.14473
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.313
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.506
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4498_KO_Hnf4g_SRP139365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9541
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05935
Fra-1_KO_GDS5078_403_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A3OU-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49777
GTEX-WHWD-2426-SM-3LK6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906841
monoatomic cation channel activity	GO Molecular Function Annotations 2023	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66705
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_signficantly_upregulated_313_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YI-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PJ34	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.7
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056791
inorganic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.441
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LTV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12868
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71991
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84227
calcium-release channel activity	GO Molecular Function Annotations 2023	1.0	null
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
ZNF285	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34645
ETS1	ENCODE Transcription Factor Targets	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trpmls	GeneRIF Biological Term Annotations	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070971
Adrenocortical carcinoma_ACC_TCGA-OR-A5LL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8191339-mmc1.xlsx-Table_S3_DE_genes-LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996933
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192663_1_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827201
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03227
OSC20	DepMap CRISPR Gene Dependency	1.0	3.21466
GSE129772_2_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11687
calcium ion transport	GO Biological Process Annotations 2023	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58148
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04582
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.981644
NERF2-26677805-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NRF2-20460467-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Salivary_Gland-memory b cell	Tabula Sapiens Gene-Cell Associations	1.0	3.04551
Mastocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
roles	GeneRIF Biological Term Annotations	1.0	null
CI1	CCLE Cell Line Gene Expression Profiles	1.0	1.69794
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_6_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TTC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04192
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.896781
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
BORC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
GTEX-O5YT-1826-SM-32PK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27834
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Perturb_9703_KO_Mef2a_ERP122655	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.8411
DDX51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13459
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8862
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
kidney disease	GWASdb SNP-Disease Associations	1.0	0.848917
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22965
Endosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.784
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Dorsal nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1479
Bronchial Hyperreactivity	CTD Gene-Disease Associations	1.0	1.17596
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
personality disorder	GWASdb SNP-Disease Associations	1.0	0.884
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLI2_01_143	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60065
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15981
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F0-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BTK_knockout_2_GDS1346	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.285946
RPMI-7951	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.20685
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88058
GTEX-TMMY-0626-SM-33HBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37162
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35682
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57356
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TI-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11198
USF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78911
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01906
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
leukopenia	GWASdb SNP-Disease Associations	1.0	0.484162
HS944T	CCLE Cell Line Gene CNV Profiles	1.0	2.08654
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06195
SSTK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.032
r6 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23671
A549_Aurora A Inhibitor I_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114277
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75278
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
PMC4198693__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28368
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.21695
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86983
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7482
GSC cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Adenoma of small intestine_Intestinal Epithelium_GSE422	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.54589
iron ion transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-500a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
chr1_84931603_G_C_b38	GTEx eQTL 2025	1.0	2.15182
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36357
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92995
Gastric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95038
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21025
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951721
Pinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.004
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64402
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22848
GSE146074_0_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36574
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04346
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16901
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMRM-1226-SM-447C6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06638
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
RS411	CCLE Cell Line Gene Expression Profiles	1.0	1.52805
GSE168676_0_v_3_dach1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2022_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.92976
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38932
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886982
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80505
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15414
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051235
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16045
Endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.843
hsa-miR-591	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
16166618-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.32541
hsa-miR-4641	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.880893
ATPase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.176
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.046568
Perturb_1213_KO_Zfp580/Sp3_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.60589
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.076595
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22591
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lymphopenia	GWASdb SNP-Disease Associations	1.0	0.751374
GSE159206_1_v_3_drd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJHI-0726-SM-3DB92	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836101
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55317
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOSB_FOSB	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20772
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
Prostate adenocarcinoma_PRAD_TCGA-HC-A76X-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ca2	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Astrocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94W-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084927
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-99-TFAP2E_TFAP2E	Rummagene Transcription Factor Associations 2026	1.0	null
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05635
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41454
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Platelet dense granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16189
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.39
PMC9753996-jci-132-160767-s182.xlsx-IRF4_assciated-ABCA7_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
foxa1_21151129_mcfdash7_lof_human_gpl10558_gse25315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.069918
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.431077
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00926
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
pararubral nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08074
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3919
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909804
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4243
Hsf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
UPCISCC074	DepMap CRISPR Gene Dependency	1.0	2.52429
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.083101
Hypertrophy	CTD Gene-Disease Associations	1.0	1.76559
IRF4_01_262	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59095
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878808
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5286
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1207-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11182
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.17908
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE191105_0_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1455
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33775
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Melanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.309
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23367
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-548d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYL6B	Pathway Commons Protein-Protein Interactions	1.0	null
MYH8	Pathway Commons Protein-Protein Interactions	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06718
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46U-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856064
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18717
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.843
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.07363
FOSL1_KO_GSE43695_681_mouse_lung, bleomycin treated	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HIF1A_NULL MUTATION_GDS1648_764_mouse_Hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2661-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE132408_1_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-AB2X-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63072
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
GSE186483_6_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11221
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE226249_2_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYL2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-92a-3p	MiRTarBase microRNA Targets	1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.84387
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr1_84996511_G_C_b38	GTEx eQTL 2025	1.0	1.44698
BACH1	ENCODE Transcription Factor Targets	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.715908
Seh1-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65675
abnormality of granulocytes	GWASdb SNP-Phenotype Associations	1.0	0.301264
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRFN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23085
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pax5	GeneRIF Biological Term Annotations	1.0	null
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06262
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917383
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76628
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
PRKACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29765
L428	CCLE Cell Line Gene Expression Profiles	1.0	2.33226
metal ion transport	GO Biological Process Annotations 2015	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.07801
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964365
monoatomic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
GSE172490_5_v_3_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	2.0905
GSE158438_5_v_9_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04132
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.921
GTEX-S32W-1026-SM-4AD5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984006
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35626
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6885
Multiple myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_2_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10208
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95576
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56966
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20939
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.20427
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.919
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876675
calcium ion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905109
Desvenlafaxine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.77
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.61011
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53759
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00536
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18287
TRP channels	Reactome Pathways 2024	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931568
ML-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.637
SNU119	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044915
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28138
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_11_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949084
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24554
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07359
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Ebola hemorrhagic fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00432
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7711-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3123	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40616
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GRIN2A	Pathway Commons Protein-Protein Interactions	1.0	null
regulated	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TT1TKB	DepMap CRISPR Gene Dependency	1.0	2.28366
NFE2L2-20460467-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24444
TNNT3	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MYL3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07795
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43371
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.91928
localization	GO Biological Process Annotations 2015	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53166
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92995
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074543
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830578
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856064
GSE242083,GSE242098_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-3647-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
disease	GWASdb SNP-Disease Associations	1.0	0.06487
SUZ12	ENCODE Transcription Factor Targets	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.027
RHO	Pathway Commons Protein-Protein Interactions	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
viability	GeneRIF Biological Term Annotations	1.0	null
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
Tanomastat	DeepCoverMOA Drug Mechanisms of Action	1.0	1.87
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
colon	GTEx Tissue Gene Expression Profiles	1.0	0.995495
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2632
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949339
GSE143643,GSE143644_2_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872177
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040789
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
transition metal ion transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872177
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.626094
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.844736
DMD	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_8459_KO_SOX9_SRP399992	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852628
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43702
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Spreading_targets_gene_names_163_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92264
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57329
GSE185881,GSE185884_2_v_3_ctcf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.69888
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4077721-NIHMS539023-supplement-1.pdf-0-MKX_MKX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90818
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TPM3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DES_KO_GDS4804_171_mouse_young skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Coelomic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
ACTG2	Pathway Commons Protein-Protein Interactions	1.0	null
sodium	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940038
Atrophy	CTD Gene-Disease Associations	1.0	1.51936
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45T-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43477
MYL12B	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAOS-2	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6226
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050492
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14176
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50976
Calcium signaling pathway	KEGG Pathways 2026	1.0	null
GSE223334_1_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22769
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42081
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828215
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.81538
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01768
Brn3a_KO_GDS1651_247_mouse_Embryonic (day 13.5) trigeminal ganglia - heterozygous	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S7SF-1926-SM-4AT5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42838
hsa-miR-3170	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
PCI30	DepMap CRISPR Gene Dependency	1.0	4.40445
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12739
BHT101	CCLE Cell Line Gene CNV Profiles	1.0	1.36217
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12158
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33775
Perturb_1478_KO_Ly96_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.4681
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178255_2_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SHROOM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13744
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1001_KO_Adar1_SRP360154	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.9765
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65058
Bladder-b cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.00902304
Carbamazepine	DeepCoverMOA Drug Mechanisms of Action	1.0	2.37
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PDX1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11443
CAMK2B	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.002
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34125
icSARS CoV_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.74924
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	168.795
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38846
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.708848
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884917
NR3C1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
RELA_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24873
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10494
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827745
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32548
hsa-miR-3977	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_6_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7616765-EMS198548-supplement-Data_S2.xlsx-3_DEG_2D_and_3D-D9_Up_in_3D_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
CALD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE88819_5_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
marc145	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.421212
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.966623
Growth Disorders	CTD Gene-Disease Associations	1.0	1.27316
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.01474
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-92a	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33058
u698	HPA Cell Line Gene Expression Profiles	1.0	1.01474
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.835549
NFIC	ENCODE Transcription Factor Targets	1.0	null
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39378
intermediate stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0247
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067115
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_7_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01551
H 89	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.33
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46399
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cellular anatomical entity	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.027
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BATF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.869897
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
MEG01	CCLE Cell Line Gene CNV Profiles	1.0	1.6546
CRIK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
hsa-miR-92b	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.825
hsa-miR-548b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HEY	DepMap CRISPR Gene Dependency	1.0	2.50247
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35659
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
l138.8a	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OC316	CCLE Cell Line Gene CNV Profiles	1.0	1.72456
Perturb_16585_KO_Bmal1_SRP217335	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.73985
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07463
SARS-BatSRBD_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.94641
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883482
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3859
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.231794
COLO201	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
r9 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69294
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
SB-408124	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.97
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
RPL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23818
lymphoma	GWASdb SNP-Disease Associations	1.0	0.751374
GSE239578_1_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94397
GSE247862,GSE247863_2_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8826_KD_MYEOV_SRP313537	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Stimuli-sensing channels	Reactome Pathways 2024	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25782
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
A7r5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04881
BCL11A	ENCODE Transcription Factor Targets	1.0	null
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU739	DepMap CRISPR Gene Dependency	1.0	2.75818
lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.365859
SUZ12_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RELA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02102
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05085
Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.66727
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_7_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082378
A549_Divalproex Sodium_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166347
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29674
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.168
GSE156115_2_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.005
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02852
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6835-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Superior central nucleus raphe, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70055
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.03367
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HR-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR3C1-23031785-PC12-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SKBR3	DepMap CRISPR Gene Dependency	1.0	3.5942
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239578_2_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051193
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47528
Fetal Death	CTD Gene-Disease Associations	1.0	1.34576
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24383
hematologic cancer	GWASdb SNP-Disease Associations	1.0	0.206753
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
GSE215086_5_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_1434_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.69969
Rectum adenocarcinoma_READ_TCGA-G5-6235-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973069
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.688539
PPP3CB	Pathway Commons Protein-Protein Interactions	1.0	null
TRPS1_Mutation_GDS4493_594_mouse_Whisker pads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24958
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122509,GSE122513_2_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6071
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51107
Pons, behavioral state related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19553
GSE223008_4_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32647
Prostate adenocarcinoma_PRAD_TCGA-XJ-A83F-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26369
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
splenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.369747
DES	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52536
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Parasubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01652
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLCPRF5	DepMap CRISPR Gene Dependency	1.0	2.2709
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12288
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.743226
TUBGCP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12771
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960965
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840438
MYC_KD_GSE22139_685_human_medulloblastoma	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95957
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.05089
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
personality disorder	GWASdb SNP-Phenotype Associations	1.0	0.776085
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11486
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959986
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hek293	HPA Cell Line Gene Expression Profiles	1.0	0.942013
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A479-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.59348
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24653
NDR1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
EHEB	CCLE Cell Line Gene Expression Profiles	1.0	2.58092
COS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
monoatomic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
PYGM	Pathway Commons Protein-Protein Interactions	1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
autophagy	GeneRIF Biological Term Annotations	1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10118
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.887139
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
distinct	GeneRIF Biological Term Annotations	1.0	null
NFATC3	Pathway Commons Protein-Protein Interactions	1.0	null
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15463
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A624-01A-22R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.23637
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
Autosomal dominant polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23409
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.113655
PACADD161	DepMap CRISPR Gene Dependency	1.0	4.04393
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05865
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1700_KO_Gprc5c_ERP125636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31443
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2045
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D6-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07992
Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rectum_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.12195
NO10	DepMap CRISPR Gene Dependency	1.0	3.23359
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.50198
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977404
ESCRT II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94849_1_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.9428
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
compounds	GeneRIF Biological Term Annotations	1.0	null
GSE146074_1_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111102,GSE111105_8_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917383
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06422
PPFIA1	Pathway Commons Protein-Protein Interactions	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070189
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PPP3CA	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54673
hsa-miR-1972	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
chr1_84993515_G_A_b38	GTEx eQTL 2025	1.0	1.51425
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52715
ESTRADIOL 3-METHYL ETHER	DGIdb Drug Targets 2026	1.0	2.94067
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3R1-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r3 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0049
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.326789
irinotecan_rattus norvegicus_gpl1355_gds3466	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KINSSHIP syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cdx2_21074721_jejunum_epithelium_lof_mouse_gpl10773_gse23436	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.939228
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2661
Glioma	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.162
microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.13473
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RASGRP1	Pathway Commons Protein-Protein Interactions	1.0	null
HOKUG	DepMap CRISPR Gene Dependency	1.0	4.25808
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
calcium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Intermediate filament cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.027
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29674
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186483_6_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858862
GSE148066,GSE157787_5_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55744
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5248-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_down-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WH7G-1326-SM-4LVMS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976663
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.49941
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09948
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Amoeba	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rimonabant	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
H3K27me3_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	1.65267
GSE151782_4_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45575
GSE210667_1_v_0_rfx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pontine reticular nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10986
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29674
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
Polycystin cation channel, PKD1/PKD2	InterPro Predicted Protein Domain Annotations	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42088
STK368746	DeepCoverMOA Drug Mechanisms of Action	-1.0	-4.4
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4981
RPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15258
CHEMBL383736	DeepCoverMOA Drug Mechanisms of Action	1.0	0.6
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13618
Acute Myeloid Leukemia_LAML_TCGA-AB-2956-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8405
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31462
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00584
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10469
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20643
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85587
heart muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.49941
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069687
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0399
SLC17A7	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36811
SETDB1-19884257-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.39338
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18869
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.064347
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41353
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-D_ATF4-def_IGG_8_vs_DMSO_8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE132313_1_v_0_fosl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47082
TNNT1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MINO	CCLE Cell Line Gene Expression Profiles	1.0	1.49492
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA42-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11892598-pnas.2417308122.sd05.xlsx-DEGs_of_RORC_cluster-Unnamed_3_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.61013
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Melanosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.55084
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3528
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979322
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.18326
ABT-199	DeepCoverMOA Drug Mechanisms of Action	1.0	0.45
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04215
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Primary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.958
GSE109285_3_v_4_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6571-01A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045423
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22187
BROX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04371
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7338542-41389_2020_247_MOESM6_ESM.xlsx-BRN2_2_of_3_DOWN_48_h-Symbol_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Doramapimod	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.64
CREB1	ChEA Transcription Factor Targets	1.0	null
GTEX-XUJ4-0926-SM-4BOPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1737
GSE215086_1_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
calcium channel activity	GO Molecular Function Annotations 2025	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886101
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842853
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.806488
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71231
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Erlotinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-3.07
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-8198-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
asthma	GWASdb SNP-Disease Associations	1.0	0.751374
Oxyntic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.482
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
20670856-Table2	GeneSigDB Published Gene Signatures	1.0	null
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953351
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11009
GSE48812_8_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.952108
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47928
Lung squamous cell carcinoma_LUSC_TCGA-77-8156-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ITGA1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7710-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.972868
Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.87653
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.49941
distributions	GeneRIF Biological Term Annotations	1.0	null
RPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37098
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE146865,GSE146866_4_v_3_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0076
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13267
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06228
HS611T	CCLE Cell Line Gene Expression Profiles	1.0	2.02048
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.848
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02102
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Membrane fusion priming complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.054
hematological neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.173662
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL29	DepMap CRISPR Gene Dependency	1.0	2.60712
mRNA_CTNNB1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MYC_Activation - 2 hours_GDS2025_723_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20693
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53587
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958067
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18646
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53327
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYH11	Pathway Commons Protein-Protein Interactions	1.0	null
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292079
KIF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40654
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34349
T-24 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lymphoma	GWASdb SNP-Phenotype Associations	1.0	0.650291
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0227
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0853
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24745
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
trpml	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852952
EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32884
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23402
CHEMBL1902935	DeepCoverMOA Drug Mechanisms of Action	1.0	0.19
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3611
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26186
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.672469
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Weight Gain	CTD Gene-Disease Associations	1.0	1.05423
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52Q-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.119632
Perturb_8499_OE_MYC_SRP150620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.39175
Memory Disorders	CTD Gene-Disease Associations	1.0	1.25745
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83565
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
T3M3	DepMap CRISPR Gene Dependency	1.0	2.93724
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07468
Lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.437
Sphingolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874815
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224893
neutropenia	GWASdb SNP-Phenotype Associations	1.0	0.646367
Autolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.286
BAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10743
GTEX-T5JC-0526-SM-32PM7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8246
GSE244199,GSE244200_0_v_1_chmp5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9437808-mmc3.xlsx-IPA_Upstream_regulators-IPA_Upstream_regulator_analysis_Up_regulated_genes_following_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71309
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE213219_0_v_1_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05897
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Quisinostat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.35
Organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.027
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902531
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08999
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4204
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897001
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MED30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92401
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_797_KO_Tnfaip3_SRP332632	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leads	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.14726
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.98232
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.52963
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.146158
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49348
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.296222
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.027
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991339
lysosome	GO Cellular Component Annotations 2025	1.0	null
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85034
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.97303
SUPT20H_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.35076
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05085
Lung Injury	CTD Gene-Disease Associations	1.0	1.04941
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25606
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30949
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.326789
hsa-miR-4652-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09125
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083703
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05202
FAM171A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14401
MINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52204
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10078
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953994
GSE160817_3_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28138
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21454
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02778
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84921
EP300	ChEA Transcription Factor Targets	1.0	null
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861237
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0496
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
trpml1	GeneRIF Biological Term Annotations	1.0	null
GSE185872_0_v_2_methotrexate_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SD-208	DeepCoverMOA Drug Mechanisms of Action	1.0	1.16
GSE137914_0_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
activators	GeneRIF Biological Term Annotations	1.0	null
Neutropenia	CTD Gene-Disease Associations	1.0	1.07482
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2667
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.990253
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24295
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.98741
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13695
TPM1	Pathway Commons Protein-Protein Interactions	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34921
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36278
divalent metal ion transport	GO Biological Process Annotations 2015	1.0	null
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37622
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC9	DepMap CRISPR Gene Dependency	1.0	3.35736
hsa-miR-548i	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
medial part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41311
GTEX-PWN1-2426-SM-48TDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986854
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nucleus of the solitary tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6018
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99558
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08137
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
Labellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
OVCAR-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	0.871797
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16085
lung disease	GWASdb SNP-Disease Associations	1.0	0.228165
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTC642	DepMap CRISPR Gene Dependency	1.0	2.60187
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2604
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.53883
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00327
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FEV	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.027
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COL6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25989
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14541
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20866
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09957
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	1.50362
Perturb_1365_OE_FOXP3_SRP074426	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.4219
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.758
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6N0-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
calcium channel activity	GO Molecular Function Annotations 2023	1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mucolipidosis type IV	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.446
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.07549
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.23354
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC29A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16669
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058202
Perturb_3241_OE_IK6_SRP136156	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.9634
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10762
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35244
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.18915
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2452	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40376
lysosome	GO Cellular Component Annotations 2023	1.0	null
MYBL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6854
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.6311
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TR146	DepMap CRISPR Gene Dependency	1.0	3.36293
Spleen-cd8-positive, alpha-beta memory t cell	Tabula Sapiens Gene-Cell Associations	1.0	1.67856
chemical	GeneRIF Biological Term Annotations	1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410111
H3K27me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Endolysosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.385
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21568
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.063313
PSS131R	DepMap CRISPR Gene Dependency	1.0	3.32052
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHEMBL1643306	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.42
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.200322
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.067641
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.834
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISO-1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-5.52
Perturb_1408_KO_Pth1r_SRP341470	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.303
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
appears	GeneRIF Biological Term Annotations	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.34459
Tubular endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.609
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862686
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15993
PMC9399107-41467_2022_32627_MOESM6_ESM.xlsx-7_B-cell_subsets-gene_name_Bcell_C5_NR4A1_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045323
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37287
496100382_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62284
Recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.214
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.92087
PPARD	ChEA Transcription Factor Targets	1.0	null
NFATC2	Pathway Commons Protein-Protein Interactions	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.2777
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
8-MG-BA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834989
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.681792
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lysosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.31
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8532
AZ505	DeepCoverMOA Drug Mechanisms of Action	1.0	0.54
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206516,GSE206518_0_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hemolymph vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08412
Oleanolic Acid	DeepCoverMOA Drug Mechanisms of Action	1.0	0.42
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.67579
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08771
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A4S6-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
major	GeneRIF Biological Term Annotations	1.0	null
Charcot-Marie-Tooth disease type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01587
hsa-miR-32-5p	MiRTarBase microRNA Targets	1.0	null
Niemann-Pick disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glioblastoma multiforme cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr1_84996982_T_G_b38	GTEx eQTL 2025	1.0	2.56449
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900861
Perturb_1494_KO_Sf3b6_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.46454
Perturb_6373_KD_COP1_SRP073333	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE153124_4_v_3_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RN-1734	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.0983
colocalizing	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824842
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.14113
Perturb_1134_KO_Tcf3/Tcf4_SRP063508	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.39847
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45091
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05725
pre-B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
Death	CTD Gene-Disease Associations	1.0	1.02373
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
pou5f1_20526341_human_embryonic_stem_cells_hesc_lof_human_gpl6947_gse21135	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.431675
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05617
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79232
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896575
H4K20me1_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_9_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9795
JVM2	CCLE Cell Line Gene Expression Profiles	1.0	2.048
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5497-01A-02R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548ab	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8161
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1903
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
localization	GeneRIF Biological Term Annotations	1.0	null
Glioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.43
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65189
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00223
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.097762
PMC6433273-pone.0214296.s009.xlsx-Table_C-S3_Table_Differentially_expressed_mRNAs_in_human_primary_monocytes_after_6_hours_of_LPS_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851606
GTEX-VJYA-2026-SM-4KL1K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885045
colonrectum_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.959657
CAOV3	DepMap CRISPR Gene Dependency	1.0	2.25387
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185519_6_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TNNC2	Pathway Commons Protein-Protein Interactions	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999715
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89111
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40306
PSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45586
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79976
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205291,GSE205292_1_v_3_drd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
e1a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
Perturb_16833_Mut_Runx3_SRP349093	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.8176
CDY2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63669
STL336112	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.52
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8373
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUSP1_KO_GDS1606_773_mouse_spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Calcineurin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.52
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3329_KO_miR24_SRP092642	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.0693
TNNC1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12451
Perturb_16934_KD_GLI1_SRP286421	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Amphisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.392
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911526
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957492
Perturb_15184_KD_SREBP_SRP190161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.33818
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00534
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961366
Contractile vacuole complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876675
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.156495
gfi1b_22201127_amulv_gof_mouse_gpl6246_gds4302	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.02837
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41701
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.128338
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mhc protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.125491
BCL11A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ML SA1	DGIdb Drug Targets 2026	1.0	2.94067
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879738
Familial hemiplegic migraine 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
hsa-miR-320e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
AKAP9	Pathway Commons Protein-Protein Interactions	1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061332
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PKACA	Kinase Library Serine Threonine Kinome Atlas	1.0	null
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.48128
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6DY-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RALDH2_KO_GSE43578_6_mouse_head (rostral or posterior)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lysosomal lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.07
recycling	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUJ4-1126-SM-4BOPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842008
22RV1	DepMap CRISPR Gene Dependency	1.0	2.33297
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
ACTA2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8405683-41419_2021_4120_MOESM2_ESM.xlsx-Sheet1-Table_S2_MYCN-responsive_gene_list_1_5_fold_p_0_05_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A551-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49791
icSARA deltaORF6_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.34242
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03375
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11709
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ion channel transport	Reactome Pathways 2014	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.8623
GSE153341_2_v_3_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTLL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02786
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04293
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SYK_druginhibition_284_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.58036
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32188
GSE57871_6_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16083
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
leukocyte disease	GWASdb SNP-Disease Associations	1.0	0.448887
GSE147669_2_v_1_tram2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Diseases	CTD Gene-Disease Associations	1.0	1.07234
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12523
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1196
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43544
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.18516
impaired neutrophil chemotaxis	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WM-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30006
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-122	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25808
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52096
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.43146
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mucolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.97317
trpml3	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KM-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2607
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Q7-0826-SM-4AD5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3474
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49515
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.04679
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.81825
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070809
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
OVCA420	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3872
Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914315
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AZD1152	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.34
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08854
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.231664
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889873
TPM2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE77857_1_v_2_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07576
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT5H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67192
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22502
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6515-01A-21R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917383
PMC12634441-41375_2025_2771_MOESM7_ESM.xlsx-RNAseq-Table_S2_Bulk_RNA-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856064
MITF	ChEA Transcription Factor Targets	1.0	null
Perturb_6372_KD_COP1_SRP073333	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
constitutively	GeneRIF Biological Term Annotations	1.0	null
GSE142430_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r3 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02984
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26816
BICR31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92457
PMC4728380-ncomms10153-s11.xlsx-M2069-BILD_MYC_ONCOGENIC_SIGNATURE_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_15_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80426
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0399
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.10592
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835726
GTEX-PWOO-0726-SM-2I3EB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856076
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
TNNI1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inorganic cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Contractile vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.141259
starvationinduced	GeneRIF Biological Term Annotations	1.0	null
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34921
lysosomal membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967004
GSE161295_4_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE151782_3_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
subset	GeneRIF Biological Term Annotations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN464	DepMap CRISPR Gene Dependency	1.0	3.33323
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993106
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845458
Plasmacytoid dendritic cell_Blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
U-251MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85113
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0139
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48623
Phagocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.823
Mucolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.328
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-1726-SM-4DXTD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05127
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929548
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11279
CAL-72	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
Embryo Loss	CTD Gene-Disease Associations	1.0	1.03419
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38882
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GSE166169_0_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.267768
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8058
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20402
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958577
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052518
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.211933
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JVM3	CCLE Cell Line Gene Expression Profiles	1.0	2.05576
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PPFIA3	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34284
GSE185519_1_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2116
Coelomocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.27875
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE85723,GSE85833_1_v_0_huwe1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.051557
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24653
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16866
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43477
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21724
EGR1	ENCODE Transcription Factor Targets	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.45115
HIPK2_overexpression_28_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.83061
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02399
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.049239
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906307
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27346
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2014
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.15695
PMC5577301-in-17-237-s001.xls-AR_upregulated_DEGs-Heart_GSE9377_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35059
GSE86507,GSE86509_3_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A44A-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.643572
GSE198165,GSE198166_6_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_28_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CEP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94155
Leukemia_promyelocytic-HL-60	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.855755
GSE111102,GSE111105_1_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35244
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57851
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08683
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048912
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830381
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	0.849326
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26186
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20897
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autophagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.663
GTEX-REY6-1726-SM-48FDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0052
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.945
Ion channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.861
Indapamide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.89
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05606
biological_process	GO Biological Process Annotations 2015	1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
HH	CCLE Cell Line Gene Expression Profiles	1.0	1.46142
VIM	Pathway Commons Protein-Protein Interactions	1.0	null
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03443
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23414
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Arterial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
Hyperkinesis	CTD Gene-Disease Associations	1.0	1.03715
Anemia	CTD Gene-Disease Associations	1.0	1.12703
HT-1197 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
liminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04156
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40242
Micropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3778
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUNB_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22769
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-1326-SM-48U1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08768
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9314667-Table_1.xlsx-Regulons-TFAP2A_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Fabry disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
AMPKA2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91913
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Endometrial spiral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24726
NRF1	JASPAR Predicted Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A268-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE124410_3_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135562
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5263239-mmc2.xls-ML2_-_MLL-AF6-Non-spreading_targets_gene_names_65_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
there	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58912
Perturb_15225_KD_lncRNALFAR1_SRP101771	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.6091
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33887
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21695
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07437
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
chr1_85001362_T_C_b38	GTEx eQTL 2025	1.0	3.42025
RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
19505326-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGC-1alpha_Deficiency_GDS4904_310_mouse_Aged gastrocnemius muscle - 10 weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE132948,GSE132949_4_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.638
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RASGRP4	Pathway Commons Protein-Protein Interactions	1.0	null
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.096
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43584
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
POU2F2	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20784
ICC137	DepMap CRISPR Gene Dependency	1.0	3.1913
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.99259
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAADP-sensitive calcium-release channel activity	GO Molecular Function Annotations 2025	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.85445
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ulipristal	DeepCoverMOA Drug Mechanisms of Action	1.0	1.2
SSR128129E	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.47
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42005
t69-brown-adipose_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	4.36526
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.231664
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8208-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11364
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072474
USF2	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of neutrophils	GWASdb SNP-Phenotype Associations	1.0	0.384088
ROS50	DepMap CRISPR Gene Dependency	1.0	6.42964
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
Secondary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.417
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STXBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_795_KO_Tnfaip3_SRP332632	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Nucleus of the solitary tract, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17589
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16755
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051254
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
inorganic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.189651
assemblies	GeneRIF Biological Term Annotations	1.0	null
GSE129772_2_v_1_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7481169-277_2020_4194_MOESM9_ESM.xlsx-RUNX1_R174L-RUNX1_R174L_mutant_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
C2BBE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46654
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
transcriptional	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LU134A	DepMap CRISPR Gene Dependency	1.0	3.58241
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087103
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1658
mRNA_POU5F1_20526341	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TMOD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116299_6_v_1_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
D-54MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
ICC10	DepMap CRISPR Gene Dependency	1.0	2.01604
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5842026-mmc5.xlsx-HIC1_directTargets_72h-Gene_symbol_HIC1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYH3	Pathway Commons Protein-Protein Interactions	1.0	null
Tongue-immune cell	Tabula Sapiens Gene-Cell Associations	1.0	1.45074
GTEX-P4PP-1426-SM-3NM9L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47852
EBF1	ENCODE Transcription Factor Targets	1.0	null
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31678
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46458
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Early endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.919
GSE148510_1_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BZRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.452029
XEN445	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
GSE120612_4_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23965
Kidney-b cell	Tabula Sapiens Gene-Cell Associations	1.0	0.235677
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60025
Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20945
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982598
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ripasudil	DeepCoverMOA Drug Mechanisms of Action	1.0	0.43
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44983
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24303
Lung squamous cell carcinoma_LUSC_TCGA-39-5021-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844581
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.717
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06701
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PXN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS695T	DepMap CRISPR Gene Dependency	1.0	2.42771
C1QL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11761
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TTI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23491
lysosomal membrane	GO Cellular Component Annotations 2025	1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-1303	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29359
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3292
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18203
ARPE-19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50603
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924095
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.48811
intermediate stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31678
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43147
SNAP25	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20784
Perturb_11938_KO_SPI1_ERP119419	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.9502
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21275
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-125a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.512291
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00341
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.00736
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
class	GeneRIF Biological Term Annotations	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal innate immunity	MGI Mouse Phenotype Associations 2023	1.0	null
GSE131887_1_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of lymphocytes	GWASdb SNP-Phenotype Associations	1.0	0.650291
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS422	DepMap CRISPR Gene Dependency	1.0	4.73471
Neoplasms	CTD Gene-Disease Associations	1.0	1.30269
NEFL	Pathway Commons Protein-Protein Interactions	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CNGB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
TRP channels	Reactome Pathways 2014	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Dyslipidemias	CTD Gene-Disease Associations	1.0	1.23743
THP1	CCLE Cell Line Gene Expression Profiles	1.0	1.42133
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBLC1	DepMap CRISPR Gene Dependency	1.0	2.30008
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Down_REST	Rummagene Transcription Factor Associations 2026	1.0	null
tissuespecific	GeneRIF Biological Term Annotations	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47666
19249085-TableE3	GeneSigDB Published Gene Signatures	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33415
chr1_84984944_T_C_b38	GTEx eQTL 2025	1.0	2.52045
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83668
hsa-miR-320d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2358
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050505
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Parotid acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A5NE-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25751
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.38807
Nephrotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62485
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E2-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIPSNAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59893
OBF-1_NULL MUTATION_GDS3473_571_mouse_Bone marrow pre-BII cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40616
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40564
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.19239
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94626
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27958
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16849
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0757
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5596
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43477
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09595
SRY	ChEA Transcription Factor Targets	1.0	null
Perturb_3367_KO_H1_SRP234772	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.73514
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4393
STAT1	ENCODE Transcription Factor Targets	1.0	null
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2584
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951782
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18055
MM1S	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60748
(S)-Selisistat	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845734
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.183
r4 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11364
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0936
SYT5	Pathway Commons Protein-Protein Interactions	1.0	null
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31996
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97652
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.231794
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902766
GSE186483_1_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BICR22	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74106
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23174
Adrenocortical carcinoma_ACC_TCGA-OR-A5LN-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67F-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53749
Ileum smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28715
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-g-Classification_of_camel_SON_basal_genes_-_ion_channels_SON	Rummagene Transcription Factor Associations 2026	1.0	null
Melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.759
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.22948
YY1	ENCODE Transcription Factor Targets	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	1.0	1.81733
chr1_84993616_T_TAG_b38	GTEx eQTL 2025	1.0	1.00773
activated	GeneRIF Biological Term Annotations	1.0	null
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14946
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13959
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32393
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28221
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5893-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.050894
GSE202434,GSE202438_12_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Natural killer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
Intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.027
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05078
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876675
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03325
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887833
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.666
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sitagliptin	DeepCoverMOA Drug Mechanisms of Action	1.0	1.19
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05085
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05716
BATF	ENCODE Transcription Factor Targets	1.0	null
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42908
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086682
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29674
L1236	CCLE Cell Line Gene Expression Profiles	1.0	2.90609
(S)-(-)-Pindolol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKCZ	Pathway Commons Protein-Protein Interactions	1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065852
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
subcellular	GeneRIF Biological Term Annotations	1.0	null
MYL4	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.656
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54116
C127I cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.77
GSE215086_3_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRABD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69308
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3834
FEM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17175
Bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.989
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5873
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.162599
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.027
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal chemokine secretion	MGI Mouse Phenotype Associations 2023	1.0	null
SUPHD1	CCLE Cell Line Gene Expression Profiles	1.0	1.73262
GSE137928_0_v_1_blebbistatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916737
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GLO1_OE_GDS4991_546_mouse_anxiety disorders	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36811
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11539
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74387
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8696
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.34227
GSE199899_1_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bronchial disease	GWASdb SNP-Disease Associations	1.0	0.751374
SK-MEL-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.951
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.33583
DT-40 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart conduction disease	GWASdb SNP-Disease Associations	1.0	1.00148
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974057
E2F6	ENCODE Transcription Factor Targets	1.0	null
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.064825
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHHNB11	DepMap CRISPR Gene Dependency	1.0	3.27962
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1568	CCLE Cell Line Gene CNV Profiles	1.0	1.46493
IKZF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_1752_KO_Runx1_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938789
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15628
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19492
hsa-miR-363	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9123
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943845
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31317
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43159
Central amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24773
Glucagonoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC8525330__F3	PFOCR Pathway Figure Associations 2024	1.0	null
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00079
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RASGRF2	Pathway Commons Protein-Protein Interactions	1.0	null
MYBPC2	Pathway Commons Protein-Protein Interactions	1.0	null
GRIN2D	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88Q-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3417
ZNF324	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93555
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04816
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cd59	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6281
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_18391_KO_923_SRP286259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.69276
PMC4486168-pone.0131961.s006.xlsx-Sheet1-ARID3B_Upregulated_Genes_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-intersection_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135312_1_v_2_bmpr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PHOSPHATIDYL (3,5) INOSITOL BISPHOSPHATE	DGIdb Drug Targets 2026	1.0	1.7644
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14479
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12051
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Thyroid	GTEx Tissue Gene Expression Profiles 2023	1.0	7.1188
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.108028
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MQ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46627
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
9505BIK	DepMap CRISPR Gene Dependency	1.0	2.96729
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
Lysosomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.21
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02371
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36651
GRIN2B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.437
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874838
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.042897
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
CTBP2	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93717
somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.557263
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.17327
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69071
Sarcoma_SARC_TCGA-DX-AB2Z-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05723
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
C1GALT1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0016
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060591
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XGQ4-2426-SM-4AT55	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944727
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	1.45515
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAMK2A	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.63468
CALM1	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01551
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1366
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07171
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.04411
NFE2L2-20460467-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899443
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Brain Diseases	CTD Gene-Disease Associations	1.0	1.19672
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J7-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTK7_KD_GSE50138_675_human_H2009	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NFE2L2	ChEA Transcription Factor Targets	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22166
Perturb_6452_KD_YAP1_SRP056665	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867049
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16546
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04468
vorinostat_homo sapiens_gpl570_gse34880	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53704
Prostate adenocarcinoma_PRAD_TCGA-H9-7775-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81745
6603-0104	DeepCoverMOA Drug Mechanisms of Action	1.0	0.71
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953994
ion transport	GO Biological Process Annotations 2015	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053981
RASGRP2	Pathway Commons Protein-Protein Interactions	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70852
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4823830-ncomms11171-s2.xlsx-GATA3_repressed_genes-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.312183
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
impaired macrophage chemotaxis	MGI Mouse Phenotype Associations 2023	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866792
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22674
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.437322
MYLK_knockdown_48_GSE14525	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.73805
KON	DepMap CRISPR Gene Dependency	1.0	2.23655
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.051283
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
FNDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29602
GSE143643,GSE143644_4_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937477
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49791
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05998
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52219
CAMK1B	Kinase Library Serine Threonine Kinome Atlas	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20O-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.77718
gm03123	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
BTK_mutant_1_GDS1346	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.566457
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05789
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7056
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76436
RET_knockout_270_GSE32093	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.11307
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
previously	GeneRIF Biological Term Annotations	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4677-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Telotristat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20866
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050786
hsa-miR-1226	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_17_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195582_3_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE215086_8_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11938
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
GSE226259_0_v_1_scd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3156-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
TP63	ChEA Transcription Factor Targets	1.0	null
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
GSE237984_1_v_0_magi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Astrocytoma	DisGeNET Gene-Disease Associations	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0536
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36017
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.35969
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XBED-1326-SM-4AT4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97152
Pancreatic ductal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28467
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06215
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.12911
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843804
ITGB5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02183
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WX-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMPKA1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Subceruleus nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33075
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RFC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01961
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31987
NAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4404
DHRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31751
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MEF2A	ENCODE Transcription Factor Targets	1.0	null
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12937
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22848
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7806814-41598_2020_80145_MOESM3_ESM.xlsx-CombinedResults_TreatbySexMainE-Supplementary_Table_S2_Genes_with_significant_FDR_0_05_sex_by_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02116
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986942
SF-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.522
abnormal neutrophil cell number	GWASdb SNP-Phenotype Associations	1.0	0.646367
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94849_3_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7441006-41388_2020_1389_MOESM2_ESM.xlsx-Supplementary_Table_1-Prostate-Specific_MYC_Overexpression_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBED-0926-SM-48TCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825461
PMC11951866-mmc1.pdf-78-SMAD4_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
GSE146074_0_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918316
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
t62-spleen_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.17452
OVOL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5072
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57013
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH838	CCLE Cell Line Gene CNV Profiles	1.0	2.596
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thymus-memory b cell	Tabula Sapiens Gene-Cell Associations	1.0	4.02431
hsa-miR-513a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4789-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35865
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I5-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA10	CCLE Cell Line Gene Expression Profiles	1.0	1.41315
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04676
GSE208435_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846884
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYBPC3	Pathway Commons Protein-Protein Interactions	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3766
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S2.xlsx-S2B_in_vivo_shared-Suppl_Table_S2B_shared_genes_between_RCAS-YAP1-MAMLD1-dR3R1_RCAS-YAP1-FAM118B_RCAS-YAP1-TFE3_in_vivo_tumors_RCAS_mouse_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65964
MEF2C	ENCODE Transcription Factor Targets	1.0	null
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27572
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149880_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68531
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34539
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Infertility, Female	CTD Gene-Disease Associations	1.0	1.16001
PMC10245467-mmc3.pdf-216-MTERF3_MTERF3	Rummagene Transcription Factor Associations 2026	1.0	null
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02194
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845797
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16651409-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
cardiac arrest	GWASdb SNP-Phenotype Associations	1.0	0.403939
BRSK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.856
CS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47301
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906603
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4385
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865098
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dictate	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35969
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06296
single-organism process	GO Biological Process Annotations 2015	1.0	null
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.32738
GSE140651,GSE140653_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049605
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51651
GTEX-S3XE-1126-SM-4AD4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83701
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.866
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
TCF3	ENCODE Transcription Factor Targets	1.0	null
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11179
Prostate adenocarcinoma_PRAD_TCGA-EJ-5521-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15123
hsa-miR-548v	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41581
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25966
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11724
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.70438
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43913
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917383
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12410147-NIHMS2099518-supplement-5.xlsx-z-scores_E4DEG_DGATiLPS_vs_LPS-Z-scores_for_genes_differentially_expressed_when_comparing_DGATi_LPS_treatment_to_LPS_alone_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879675
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09062
MYL1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_6132_OE_Tfeb_SRP157662	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.19495
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31754
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06973
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3299_KO_Bmpr1a_SRP116199	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.62258
GSE210476_11_v_10_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.230958
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTN3	Pathway Commons Protein-Protein Interactions	1.0	null
SCA1_Knock-in_GDS3544_561_mouse_Cerebellum - 4 Weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
small	GeneRIF Biological Term Annotations	1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRU-12	DGIdb Drug Targets 2026	1.0	2.94067
AR	ChEA Transcription Factor Targets	1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15314
SAOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09885
PMC9041830-ppat.1010464.s009.xlsx-MAGeCK_MLE_output-STAT1-KO-Gene_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
death	GeneRIF Biological Term Annotations	1.0	null
NCI-H838	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
Hemolysis	CTD Gene-Disease Associations	1.0	1.04201
Fibrosis	CTD Gene-Disease Associations	1.0	1.50248
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sudden cardiac death	GWASdb SNP-Phenotype Associations	1.0	0.880765
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.066822
496100503_HIP_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1727
pregeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20855
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912129
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A762-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mucolipidosis	DisGeNET Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-A475-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-767-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85851
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8373
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11259
NUPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00576
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A876-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7297
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72456
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5915
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02316
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21119
SORBS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ARGLU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08695
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE140651,GSE140653_5_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	2.10222
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.944813
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.3395
OC314	CCLE Cell Line Gene CNV Profiles	1.0	1.60253
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50907
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.7297
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04276
CHCHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11444
Helam	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02623
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00821
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
neutropenia	GWASdb SNP-Disease Associations	1.0	0.747373
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum	HPA Tissue Gene Expression Profiles	1.0	1.02422
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939093
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.086061
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8108288-gutjnl-2020-321731supp004.xlsx-LPS_stimulation-gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.2501
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060151
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
DLG4	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23402
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09837
GSE199543,GSE239447_0_v_6_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
complexes	GeneRIF Biological Term Annotations	1.0	null
Spleen-memory b cell	Tabula Sapiens Gene-Cell Associations	1.0	4.63184
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02866
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C1-23031785-PC12-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845214
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal leukocyte count	GWASdb SNP-Phenotype Associations	1.0	0.384088
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38665
RNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08851
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.516934
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
long	GeneRIF Biological Term Annotations	1.0	null
GTEx AdiposeTissue 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	15.2737
trpml2	GeneRIF Biological Term Annotations	1.0	null
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46801
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06585
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Vacuolar lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.022
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01807
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7817
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.284607
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4894
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.848
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.26856
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03128
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054763
REST	ENCODE Transcription Factor Targets	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10794
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29674
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32021
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229671,GSE229673_0_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183335,GSE183351_3_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Early endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
NRF2-20460467-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06054
Baricitinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.09
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cdx2_21402776_jejunum_epithelium_lof_mouse_gpl11044_gse24633	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.265705
GSE183316,GSE183317_4_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
thp1	HPA Cell Line Gene Expression Profiles	1.0	1.11405
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IC-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP4K5_knockdown_199_GSE61497	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-4.30473
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47082
SPI1	ENCODE Transcription Factor Targets	1.0	null
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.18707
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prednisolone_homo sapiens_gpl570_gse32962	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lytic vacuole membrane	GO Cellular Component Annotations 2025	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.58731
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28735
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_237_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MEF2C_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37291
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35747
abnormal chemokine level	MGI Mouse Phenotype Associations 2023	1.0	null
Gfi1b_OE_GDS4302_425_mouse_AMuLV (pro-B Abelson leukemia virus transformed) cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSK3_INHIBITION_GDS4043_459_human_MLL leukemia cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
T-98 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.618
Perturb_4592_KD_EBNA1_SRP064652	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.15229
Edema	CTD Gene-Disease Associations	1.0	1.12461
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4530	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.324
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4305	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CHD2	ENCODE Transcription Factor Targets	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.841449
Late endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.278
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
Charcot-Marie-Tooth disease type 4J	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6182
DUSP1_KO_GDS1606_772_mouse_spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6970-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146074_9_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S5-Supplemental_Table_S5_Genes_commonly_downregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE254517_1_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Intracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.305
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
TNNI3	Pathway Commons Protein-Protein Interactions	1.0	null
channel	GeneRIF Biological Term Annotations	1.0	null
GSE209698_0_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35241
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905256
Prostate adenocarcinoma_PRAD_TCGA-VN-A88L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.123703
19351829-Table1	GeneSigDB Published Gene Signatures	1.0	null
ChIP_DMAP1_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11061611-cd-23-0857_table_s4_suppst4.xlsx-Myeloid_F2-pM2_FU2_unique_LEF1_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.09011
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05747
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
NFATC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895199
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21875
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mcoln2	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_26_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_1136_KO_Id3_SRP063508	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
cellular process	GO Biological Process Annotations 2015	1.0	null
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061777
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
leukopenia	GWASdb SNP-Phenotype Associations	1.0	0.646367
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
hierarchy	GeneRIF Biological Term Annotations	1.0	null
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HUT102	CCLE Cell Line Gene Expression Profiles	1.0	2.22816
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01551
PRKCB	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92206
RIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46141
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146074_6_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_5728_KO_Cdh1_SRP149531	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.51418
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7306-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23409
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_29_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902577
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4033
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31128
LMOD1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_2486_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GSE239578_0_v_6_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125403_3_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RASGRF1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lowering	GeneRIF Biological Term Annotations	1.0	null
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933604
hsa-miR-365	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07119
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
calcium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988901
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.04679
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35626
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218098,GSE218099_1_v_0_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37982
RUNX1_01_344	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.70862
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05286
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13516
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905265
arrhythmia	GWASdb SNP-Phenotype Associations	1.0	0.22576
intermediate stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15873
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13136
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863687
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916737
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.1447
GSE231799_2_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-320c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
rectum_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.880424
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33162
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1862
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
calcium ion transport	GO Biological Process Annotations 2015	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08157
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
NCIH1915	DepMap CRISPR Gene Dependency	1.0	2.07149
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90591
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951782
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82889
single-organism localization	GO Biological Process Annotations 2015	1.0	null
B3GNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00777
UNC13B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836379
BCL11A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08203
NCI-H522	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYH6	Pathway Commons Protein-Protein Interactions	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11319
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
RPMI-8226 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85682
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPM-1426-SM-3TW8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40624
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYL9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WEY5-1526-SM-4LMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0813
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4755-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE117643_1_v_0_irx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1479
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE88819_0_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067701
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46137
abnormality of myeloid leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.20085
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.430768
post-lysosomal vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
Perturb_16775_KO_Utx/Jmjd3_SRP339500	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.81706
U-266 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDVN-0726-SM-4B64L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895405
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91298
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.267768
SYNJ2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07563
GSE213219_2_v_3_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47545
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04007
TNNT2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.414678
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903166
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.844736
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PRPSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14002
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962119
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88249
Skin-cd1c-positive myeloid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.328494
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GSE171826_1_v_3_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Central amygdalar nucleus, capsular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16466
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6481-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE62843,GSE64371_4_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056762
NDR2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE171826_1_v_0_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
endolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.797436
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16651414-Supp2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04979
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24436
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.38332
GSE223008_4_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Q7-0426-SM-3K2BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19136
VCL	Pathway Commons Protein-Protein Interactions	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
such	GeneRIF Biological Term Annotations	1.0	null
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73811
NAA50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10011
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
Gbm cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.228
inorganic ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03643
GSE202434,GSE202438_2_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	1.85191
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92301
H3K27me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79642
mantle zone of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41311
hsa-miR-367	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.418
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
ELF3-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r2 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36017
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87692
gm01607	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.163
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.051889
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.17801
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907816
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67847
periventricular stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69294
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.29088
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuronal ceroid lipofuscinosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
Endolysosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.062
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87747
CNGA1	Pathway Commons Protein-Protein Interactions	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96915
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.96482
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14832
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tonsil	HPA Tissue Gene Expression Profiles	1.0	0.900642
Perturb_2055_KD_NR2F2_ERP124128	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.069999
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Gangliosidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055421
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-824	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
GSE137144_5_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.814
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857773
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103857
Perturb_3399_KO_Tcf7_SRP077563	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.5596
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40125
MYL6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.44079
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SORBS3	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09915
POLR2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04613
GSE196407_1_v_0_fluorouracil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE198165,GSE198166_6_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3024
cellular_component	GO Cellular Component Annotations 2015	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951017
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Guanfacine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.6
active	GeneRIF Biological Term Annotations	1.0	null
GTEX-SE5C-1526-SM-4BRWU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32023
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PK45H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82667
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10401
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90775
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870654
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5702
UACC893	DepMap CRISPR Gene Dependency	1.0	10.1234
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.844736
Intracellular anatomical structure	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	3.027
icSARS-Cov_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45888
RGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03931
Serum sulfate level	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832483
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.885
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5811
HOXA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43756
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01551
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TP63_01_202	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60544
Gaucher's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6692-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8371
GTEX-NFK9-1726-SM-3TW8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06189
GSE184884_7_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus of the solitary tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14426
GRANTA519	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6997
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
overload	GeneRIF Biological Term Annotations	1.0	null
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91519
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.159578
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
PMC11185845-NIHMS1996282-supplement-Table_S1.xls-TableS1_txt-CB_TBL1XR1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.620621
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16578
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
Lymph_Node-memory b cell	Tabula Sapiens Gene-Cell Associations	1.0	4.58121
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34921
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869374
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844863
GSE160817_3_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_STAT3_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
t69-brown-adipose_male_1w	MoTrPAC Rat Endurance Exercise Training	-1.0	-2.7348
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.49941
IRF4	ENCODE Transcription Factor Targets	1.0	null
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02446
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NF-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
Infertility, Male	CTD Gene-Disease Associations	1.0	1.48582
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	2.20532
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TTN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29178
GRHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02014
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19663
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70668
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51J-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3914
versa	GeneRIF Biological Term Annotations	1.0	null
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0522
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
KDM4A	ENCODE Transcription Factor Targets	1.0	null
PMC9038526-mmc1.xlsx-healthy_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.58
divalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.100934
Macitentan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.84
AHRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29929
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.272995
b-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.521223
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.166
GSE94849_7_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03115
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00894
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22546
Stimuli-sensing channels	Reactome Pathways 2014	1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23665
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13833
hsa-miR-3691-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.359357
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00266
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160817_0_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.823
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.972744
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.944
Pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.285
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45347
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01411
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GSE114992,GSE114993_1_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr1_84953993_A_G_b38	GTEx eQTL 2025	1.0	3.23721
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.751374
IGFLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28522
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09934
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6018
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11984
15845616-Table3	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20836
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41364
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.99472
DAOY	CCLE Cell Line Gene CNV Profiles	1.0	1.56201
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31502
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845641
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C6-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.13751
controlling	GeneRIF Biological Term Annotations	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	4.92971
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966037
PFEIFFER	CCLE Cell Line Gene Expression Profiles	1.0	1.60872
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12559107-12035_2025_5221_MOESM1_ESM.xlsx-Supplment_Tab_3-Supplement_Tab_3_The_result_of_MR_analysis_for_SCZ_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
RERFLCKJ	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
establishment of localization	GO Biological Process Annotations 2015	1.0	null
RMDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28064
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.839
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.67007
H3K27me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22313
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF1	ENCODE Transcription Factor Targets	1.0	null
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.16195
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2076
GATOR1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00472
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.231206
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.467273
GSE165682_4_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ8I-2126-SM-4BOOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19851
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
extracellular	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88058
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04058
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.206753
CAMK1D	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13844
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3116
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.7333
late endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.615437
Lymph_Node-b cell	Tabula Sapiens Gene-Cell Associations	1.0	11.6691
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10456
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860206
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548u	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
concentration	GeneRIF Biological Term Annotations	1.0	null
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.45376
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040382
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28786
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49791
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878851
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32407
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10922
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901644
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
agranulocytosis	GWASdb SNP-Disease Associations	1.0	0.747373
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BTK_KO_GDS1346_302_mouse_splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE168676_2_v_3_dach1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228413_4_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967319
Cation channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.85
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35077
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Perturb_1807_KO_lncFAO_SRP192861	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.10265
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044887
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136238_1_v_2_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
obstructive lung disease	GWASdb SNP-Disease Associations	1.0	0.382211
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01366
ERRalpha_Deficiency_GDS2727_646_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34264
GSE246567_0_v_1_acat2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
SOD2_KO_GDS1080_128_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990026
GSE206729_3_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2157_KO_Tnfaip3_SRP126279	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.0755
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26858
form	GeneRIF Biological Term Annotations	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
CAMK2G	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-D_ATF4-def_IGG_8_vs_DMSO_8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Paroxetine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.67
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39675
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PYGB	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
PMC4198693__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829194
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-320a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IRS1_KO_GDS1219_303_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18342
PRU-10	DGIdb Drug Targets 2026	1.0	2.94067
daudi	HPA Cell Line Gene Expression Profiles	1.0	1.07809
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61309
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.54019
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.861935
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.911645
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24139
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.961291
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53749
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50I-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
adpribosylation	GeneRIF Biological Term Annotations	1.0	null
NB13	DepMap CRISPR Gene Dependency	1.0	6.07551
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54634
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79334
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03375
GSE114992,GSE114993_1_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32021
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4659b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BL41	CCLE Cell Line Gene Expression Profiles	1.0	1.38555
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31765
ML-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.06
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6478-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01691
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070161
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CPLX1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
SNARE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.352
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11246
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
PMC10322668-Table_7.xlsx-DE_genes_at_early_infection-List_of_de-regulated_genes_at_early_interaction_time_point_of_Dm28c_T_cruzi_THP1_infected_cells_From_Libisch_2020_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54634
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Jejunal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.146
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06664
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ONDA8	DepMap CRISPR Gene Dependency	1.0	6.62233
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876675
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16045
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.33316
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958851
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970758
MRPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07752
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4219345-1471-2121-14-52-S4.xlsx-BORIS_6dN-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21124
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mhs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165682_2_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
15845616-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00414
Gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A47G-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.01249
TNNI2	Pathway Commons Protein-Protein Interactions	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.39876
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943487
SCHNEIDER-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dexamethasone_homo sapiens_gpl570_gse37474	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
PMC5842026-mmc5.xlsx-HIC1_directTargets_48h-Gene_symbol_HIC1	Rummagene Transcription Factor Associations 2026	1.0	null
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066749
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16083
PMC11073998-41375_2024_2235_MOESM9_ESM.xlsx-THP1_phosphoproteome-Unnamed_2_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10497
Pneumonia	CTD Gene-Disease Associations	1.0	1.23106
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51396
lytic vacuole membrane	GO Cellular Component Annotations 2023	1.0	null
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02623
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01007
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849986
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20329
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75418
GSE111102,GSE111105_3_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9314667-Table_1.xlsx-Regulons-MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.156342
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.72711
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EB2	CCLE Cell Line Gene Expression Profiles	1.0	1.63485
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6018
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY334370	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.47
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01326
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882316
Perturb_6374_KD_COP1_SRP073333	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.49834
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE215086_1_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2619
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
RPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07961
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
THAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3865
PRKCA	Pathway Commons Protein-Protein Interactions	1.0	null
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06586
H3K36me3_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63116
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
XPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42765
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10249
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24966
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF664	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08781
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49048
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23961
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824667
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13747
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942181
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20114
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25101
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20866
BCL3	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35059
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Renal clear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.206753
ChIP_H3K27me3_18600261_mouseWholeBrain	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8373
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5289
Prostate adenocarcinoma_PRAD_TCGA-EJ-5496-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15614
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50887
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90208
PMC10852255-pone.0297872.s004.xlsx-LPS_UPstream-Upstream_Regulator_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lymphnode	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM3211	DepMap CRISPR Gene Dependency	1.0	8.66692
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38149
GSE104508_0_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neuronal ceroid lipofuscinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69567
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02756
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19447
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15933
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63318
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
Perturb_6758_Mut_TOP3B_SRP345494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CDC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0155
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.1294
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25966
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.49941
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01521
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.07024
ATAD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69741
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13604
ATF6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14318
lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.365477
GSE130217_0_v_2_sesn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2135	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999145
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12669
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35521
GSE202434,GSE202438_4_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP3R1	Pathway Commons Protein-Protein Interactions	1.0	null
CHST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3613
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.625821
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	1.35011
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPM4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88047
GOS3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33939
Sarcoma_SARC_TCGA-UE-A6QT-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.861632
well	GeneRIF Biological Term Annotations	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5516-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PAPOLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04536
CPSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
Superior central nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15656
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2555
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10934
Skin-langerhans cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0343368
GSE116810_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08123
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41468
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
causing	GeneRIF Biological Term Annotations	1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
C1orf216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14239
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16822
hsa-miR-3673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5530-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10534
endosomes	GeneRIF Biological Term Annotations	1.0	null
PYGL	Pathway Commons Protein-Protein Interactions	1.0	null
t69-brown-adipose_female_2w	MoTrPAC Rat Endurance Exercise Training	-1.0	-29.8183
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73429
H3K36me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28523
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBPC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01414
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.972057
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049474
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.61126
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13807
STK155799	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.92
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171572_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36017
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT	CCLE Cell Line Gene Expression Profiles	1.0	1.52604
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukemia	GWASdb SNP-Disease Associations	1.0	0.751374
G415	DepMap CRISPR Gene Dependency	1.0	2.37543
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.39151
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93998
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC70	DepMap CRISPR Gene Dependency	1.0	5.33143
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90096
Sarcoma_SARC_TCGA-DX-A3U6-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.19312
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101546_2_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00918
Perturb_1545_KO_Rbx1_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.98067
Human - Tonsil - L2 - LZ	HuBMAP Azimuth Cell Type Annotations	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90856
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908209
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78496
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
myocardial infarction	GWASdb SNP-Disease Associations	1.0	1.00148
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0405
ELK1	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60776
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12931
Abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46284
intermediate stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02984
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26858
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178255_2_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01331
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immune system disease	GWASdb SNP-Disease Associations	1.0	0.09896
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02751
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76357
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95126
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20431
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207832_1_v_0_usp22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.10332
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056678
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10122
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EmrE multidrug transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
Perturb_12817_KD_Stmn2_SRP148807	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.32141
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41512
GSE236511_1_v_0_ngfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPBGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50449
GTEX-XYKS-2226-SM-4E3IU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941955
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137914_4_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trastuzumab_homo sapiens_gpl570_gse15043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11648
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07959
GTEX-XMK1-0226-SM-4B65D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04988
PRKX	Kinase Library Serine Threonine Kinome Atlas	1.0	null
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0067
Rotigotine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.48
EB1	CCLE Cell Line Gene Expression Profiles	1.0	1.66947
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.815802
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Macropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.981
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
BHY	DepMap CRISPR Gene Dependency	1.0	3.68007
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1076-01A-01R-0692-07,TCGA-21-1076-01A-02R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transport of small molecules	Reactome Pathways 2024	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10702
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2409
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57382
endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.348346
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977695
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.07549
GRIN2C	Pathway Commons Protein-Protein Interactions	1.0	null
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15909
CTCF	ENCODE Transcription Factor Targets	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053982
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
histocompatibility	GeneRIF Biological Term Annotations	1.0	null
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16308
pRb_Deficiency_GDS3176_605_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE160246_0_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13452
PPFIA4	Pathway Commons Protein-Protein Interactions	1.0	null
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6018
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alveolar macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.28192
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907701
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62582
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05865
LY2090314	DeepCoverMOA Drug Mechanisms of Action	1.0	2.48
Perturb_16729_KO_miR301a_SRP131007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.8356
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4659a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE94849_7_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.082261
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056972
UMUC10	DepMap CRISPR Gene Dependency	1.0	3.75981
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JO-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05221
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-D_ATF4-def_IGG_8_vs_DMSO_8-Supplementary_Table_4D_DEGs_in_ATF4-def_cells_comparing_IGG_to_DMSO_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.525166
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01825
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14045
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22111
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82078
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13352
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880973
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
nephrotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.65907
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr1_84995229_C_A_b38	GTEx eQTL 2025	1.0	2.49772
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040308
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05045
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4077721-NIHMS539023-supplement-1.pdf-0-IRF2_IRF2	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1183
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05853
hsa-miR-552	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14137
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930124
PPFIA2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4628
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35059
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE204811,GSE204813_1_v_3_trim29_human	RummaGEO Gene Perturbation Signatures	1.0	null
stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.469203
UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2621
hsa-miR-4763-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE172490_5_v_1_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88058
SNU738	CCLE Cell Line Gene CNV Profiles	1.0	1.42686
Weight Loss	CTD Gene-Disease Associations	1.0	1.44735
Perturb_4497_KO_Hnf4a/Hnf4g_SRP139365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045637
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Deuterosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
16273092-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051935
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052393
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pulmonary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42355
GSE124410_3_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
STX1A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97255
NCI-H2196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perinuclear endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133516_5_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7780220-12943_2020_1301_MOESM8_ESM.xlsx-Fig_3A_RNA-seq_DEGs-Summary_701_LPS-induced_DEGs_361_THZ1-sensitive_DEGs_in_blue_of_macrophages_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-32	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE183316,GSE183317_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE137818_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15584
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28887
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863753
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895065
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51283
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051181
COPI-coated Golgi to ER transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.77
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07359
GTEX-S4P3-1226-SM-4AD4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837192
STAT3-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05544
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.228165
ML2-SA1	DGIdb Drug Targets 2026	1.0	8.822
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01693
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3124-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BDCM	CCLE Cell Line Gene Expression Profiles	1.0	1.82212
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08099
traffics	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vacuolar membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.195
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25267
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838385
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.839658
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
NCI-H2444	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.964941
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
hsa-miR-4429	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08194
USE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.239
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MJ	CCLE Cell Line Gene Expression Profiles	1.0	1.45353
Ion channel transport	Reactome Pathways 2024	1.0	null
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Large_Intestine-mature enterocyte	Tabula Sapiens Gene-Cell Associations	1.0	1.70388
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.94008
Duvelisib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.28
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.731423
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056164
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.07888
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.161905
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920453
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25813
TCAP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsomedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64181
SETDB1	ChEA Transcription Factor Targets	1.0	null
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875887
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.871053
chr1_85000110_T_C_b38	GTEx eQTL 2025	1.0	1.21115
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.18516
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.857047
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-320b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lytic vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.31
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844348
SYT1	Pathway Commons Protein-Protein Interactions	1.0	null
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830941
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08874
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.6317
Perturb_1709_KO_Tox_SRP054249	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.96033
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1203
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3177-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33661
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POMQ-0526-SM-3GADD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11423
SP1	JASPAR Predicted Transcription Factor Targets	1.0	null
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894949
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB3A	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_15250_KO_Dnmt3a_SRP386956	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.3188
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z2-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26186
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
transcriptionally	GeneRIF Biological Term Annotations	1.0	null
vice	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_2_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MU-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11114
intracellularly gated calcium channel activity	GO Molecular Function Annotations 2025	1.0	null
Acidocalcisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.963
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.252527
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H1-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43026
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.32203
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16867
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89006
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MEF2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37116
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67758
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50708
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33925
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary biliary cholangitis 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Brain Lower Grade Glioma_LGG_TCGA-CS-4941-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86905
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23994
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16728_Mut_Zfp36_SRP052881	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.13022
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ezh2_KO_GDS3765_515_mouse_Primary preadipocyte cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_1537_KO_Ly96_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.12785
GRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
RAB3A_KO_GDS2482_705_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.1109
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PKACG	Kinase Library Serine Threonine Kinome Atlas	1.0	null
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23409
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85239
hsa-miR-25	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44533
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.5586
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2755-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185744,GSE185747_2_v_4_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051153
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3458
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.22274
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846673
hsa-miR-4794	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11938
myocardial infarction	GWASdb SNP-Phenotype Associations	1.0	0.880765
artery disease	GWASdb SNP-Disease Associations	1.0	0.136524
GSE239578_1_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
calcium ion transport	GO Biological Process Annotations 2025	1.0	null
PMC9038526-mmc1.xlsx-postCOVID_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_2_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62633
Endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.582
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05165
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09962
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0126-SM-4AD4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99694
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921775
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE151782_4_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
crig1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546929
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892155
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.797
NAADP-sensitive calcium-release channel activity	GO Molecular Function Annotations 2023	1.0	null
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.42253
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Perturb_3361_OE_Bach2_SRP267100	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.0898
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31183
15793299-TableC	GeneSigDB Published Gene Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840806
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34795