association	dataset	threshold value	standardized value
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.262
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9288
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96055
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151782_1_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H-508	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0137
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4574
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3937
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.09804
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6822
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240027,GSE240030_5_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59395
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114690_2_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220520_5_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06475
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5296
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18674
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1008
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic translational initiation	GO Biological Process Annotations 2025	1.0	null
PMC7581777-41419_2020_3029_MOESM6_ESM.xlsx-MNX1_ChIP-Symbol_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144481,GSE144483_0_v_3_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25179
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1757
GLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1701
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5939
GSE139948_3_v_2_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
gp5d	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
formation of translation preinitiation complex	GO Biological Process Annotations 2025	1.0	null
GSE112760,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE229698_1_v_2_traf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypopharyngeal carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
ACSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47254
GTEx Brain 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-13.174
GSE203158_12_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129858,GSE129859_1_v_3_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139120_1_v_0_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7681055-ACEL-19-e13226-s015.xlsx-Sheet1-Ryk-dependent_FOXO3_targets_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0886
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2291
CNOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88225
Visceral endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
Extraembryonic tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.651
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21695
Subcortical maternal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.723
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20667
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6322
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120413,GSE120447_3_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.73981
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Trophectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2179
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGFBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39662
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.92
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2057
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71292
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA-bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9972
PMC12178829-mmc4.xlsx-Sheet_3-MEG3-KD_Down-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37712
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7482
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	173.673
GSE218580_1_v_2_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19589
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
efm19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9644
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5808
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.59681
Embryonic stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
PMC7927818-AAC.01755-20-s0002.xlsx-Supplemental_Table_1-Supplemental_Table_1_List_of_significantly_altered_genes_in_MDMs_differentiated_in_the_presence_of_PrEP_FTC_v_No_Drug_TDF_v_No_Drug_FTC_v_TDF_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143643,GSE143644_4_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
colo824	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
GSE203158_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0391
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.251
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5718
GSE179002_0_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4669
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35978
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140651,GSE140653_5_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2604
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7427
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.606
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.54474
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5817
GSE183101_0_v_1_hvcn1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hdlm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4787
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169155_3_v_7_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKLU-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.645
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
jf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.743
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8894
VGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67957
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4331
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H-1836	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.096
GSE210373_0_v_1_cntnap4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.6359
PMC12178829-mmc4.xlsx-Sheet_3-MEG3-KD_Down-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bae	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Blastocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
dms273	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.663
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.229
BCL9L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66214
Conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.416
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.82
GSE112760,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5615
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2192
ACSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84781
e2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
T/C-28a2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6735
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.186
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.622
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9378
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ht55	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
sw837	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0542
H-1694	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.02
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7395
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA_high-signal_selected_bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.9306
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5913
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2163
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6744561-41467_2019_12125_MOESM8_ESM.xlsx-SEs_in_MCF10DCIS-TCF7_cells-Enhancer_to_gene_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0627
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.25
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0011
HNF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99249
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4609
ELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15238
PCDHB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2615
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6033
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00309
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.529
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.105
GSE165682_2_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.475
Pollen coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.03
HCC-1954 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211226_1_v_2_sirpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9715
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23845
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0635
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.06363
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	1.65416
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5997
CAL-51 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.611
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6538380-elife-42374-supp3.xlsx-human-sp-ENSG00000007866_TEAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8554124-DataSheet2.XLSX-23-TBX18_TBX18	Rummagene Transcription Factor Associations 2026	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.53563
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2956
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4727
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.155
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
lxf289	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
GSE203158_5_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125782_0_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203158_12_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7662
2-iminoacetate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
MSH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73552
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4424
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9318
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223008_5_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49651
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54769
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151364,GSE151366_1_v_2_taf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50654
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2713
Spongiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199899_1_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0116
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.9189
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30697
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.2419
Cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.316
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13896
GSE180951_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3607232-mmc3.xlsx-b_RUNX1_SEM_MLLC_H3K4Me3-x_2_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF449	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99048
GSE220520_5_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9694
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9333
GTEx Brain 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-8.40641
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2527
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC-15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6543
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02826
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2465
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
C1orf216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04149
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93156_1_v_0_idelalisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8669
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1215
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11981
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2006
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1514
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2216
GSE179002_3_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6466
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0149
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40971
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9135
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5949
GSE182680,GSE182683_10_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8133
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28157
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9916
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3021
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pl90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.144
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
623 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.632
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.8722
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5289
LS-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.018
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.38549
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
Placental cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63257
SEMA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50898
protein-RNA complex assembly	GO Biological Process Annotations 2025	1.0	null
GSE246053_1_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
EXOC3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49826
GSE201309_5_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.46949
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.24481
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NOTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.191
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8171
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16701
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4065
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7487
KM-H2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
TDRD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9205
SLC44A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90578
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9317
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9979
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65677
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34945
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.4455