association	dataset	threshold value	standardized value
TMEM181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03732
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pyrenoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
CELGOSIVIR	DGIdb Drug Targets 2026	1.0	6.6165
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.969
ZRANB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54555
Mucormycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0754
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97155
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48778
TMX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4983
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70702
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.90442
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2798
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BAIAP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68041
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
Glutathione hydrolase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.819
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Spore wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
Filgotinib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.027063
CDCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76554
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14774
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.74
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1543
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79479
Ruminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.907
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79738
RNASE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57026
Dieulafoy lesion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.729
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5839
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9105
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
GSE200839,GSE233826_2_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4089
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33342
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.85695
GSE143790_0_v_1_bcl9_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.81638
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4881
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10236
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S12_LF_C1_8h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Azurophil granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4487
LB-100_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0110055
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
Amylin receptor complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.403
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
Signal peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99882
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77901
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.136
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08281
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07431
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
HSPA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69775
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05138
Progressive myoclonus epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
Sulfatinib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0200304
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.88
INPP5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06443
GSE172494_2_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36184
ING4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66328
RMC-6236_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0193112
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94745
NIPSNAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22408
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0213
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2369
SEPTIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69655
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S01_LF_C1_3h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8961
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Basolateral part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.244
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98696
Milk allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
RNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27533
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.189
CRCGN009_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89773
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04865
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80843
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
FLOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29663
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60934
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0278
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73481
alpha-glucosidase activity	GO Molecular Function Annotations 2025	1.0	null
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.857
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02471
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6248
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30849
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
PIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40797
Vortioxetine_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00932393
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.33004
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9558712-Data_Sheet_2.xlsx-POU3F4_WT_vs_CTRL-gene_name_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
SYPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88749
TAK-733_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0429832
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.774
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61602
Exoskeleton	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cob	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
MON1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24841
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09729
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5115
Anal canal squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.781
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6194
GSE94849_6_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Osmotic diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.978
FNIP-folliculin RagC/D GAP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1943
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.328
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96647
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17241
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.79
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.995
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60581
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8645
Colonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.23275
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185744,GSE185747_2_v_3_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76875
Hippocampus minor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.2725
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07596
plant-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.766
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196117_6_v_5_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58025
Glycogen metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
Tofacitinib (citrate)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0219699
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35569
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4523
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
LRRC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9286
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69953
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.9954
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91647
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44379
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79003
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3708
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52089
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1914
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15832
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74569
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14115
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21065
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05873
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45107
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83871
ECEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.878
TLCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41366
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.01119
ZHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77541
Vastus lateralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7881
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.94555
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.692
Cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.079
NHERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28469
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1113
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4087
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04873
ARAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68166
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4125
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07863
Ileal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
RAB11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13226
Quinestrol_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0238453
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7763
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24328
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26111
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Egg white	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.56526
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
CALR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90694
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3771
TAGLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64263
Fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.089
Brivudine_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0172097
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
EXOC3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49826
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ghosal hematodiaphyseal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.694
Trametinib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0220165
Congenital diarrhea 5 with tufting enteropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25554
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.531
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
NCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70518
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP4R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26442
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.08865
CCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05601
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.683
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86802
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9647
GSE94849_1_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05471
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.31987
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66711
C1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4462
Variable age at onset electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04613
Microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.527
BCL2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58168
Pellicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.524
LCORL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23731
APELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35762
Ponatinib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0308385
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22646
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.041
Amyloplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.849
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.206
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.029
Digestive juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
Ivermectin_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0163067
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98488
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41444
Ecog Performance Status 1	DisGeNET Gene-Phenotype Associations	1.0	null
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6552
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet3-RNAseq_SJIA_KD_inter_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRDM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39232
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.7425
Krabbe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
PMC11625982-AJH-100-10-s001.pdf-68-ZNF534_ZNF534	Rummagene Transcription Factor Associations 2026	1.0	null
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68751
g.8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
METTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18798
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.774
MMP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10742
Almonertinib (mesylate)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0297447
GSE132408_0_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.48515
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40706
Amylin receptor complex 3	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82124
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17592
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77594
CEP170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99639
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64899
RNF144A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61713
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7378
VOGLIBOSE	DGIdb Drug Targets 2026	1.0	6.6165
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
Scape	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
ZNF626	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07412
BEST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72096
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70316
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3261
SLC27A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83132
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03716
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
SNX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86638
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.18875
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63618
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4708
SOX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27088
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
ZNF222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36253
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22685
IKBKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47456
palbociclib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0292311
POU5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71788
ITGB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79068
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
IRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51212
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.873
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.58895
PHTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74737
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24297
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6118
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09194
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S23_LF_C1_24h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21423
Lateral part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86185
chr7_142096444_G_T_b38	GTEx eQTL 2025	1.0	1.56134
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58566
TIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21922
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15879
Secretory diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
CRCGN012_HEPG2_24H:J21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0902
EID2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39032
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41357
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
Galactose metabolism	KEGG Pathways 2026	1.0	null
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	4.15724
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47327
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pexidartinib (hydrochloride)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0294154
GSE185519_1_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.6515
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59431
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22738
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66777
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
Omeprazole (sodium)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0134021
Belzutifan_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.024979
APOBEC3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89653
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0353
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9529
GSE185519_1_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Aril	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.145
TLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98719
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
HNRNPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84097
alpha-glucosidase activity	GO Molecular Function Annotations 2023	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.774
Hydroxyfasudil_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0222073
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
Isoamylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.232
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01138
ONECUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07625
GSE157296,GSE157298_4_v_5_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98919
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45006
Plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.854
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.818
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.96315
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24383
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135352_6_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19889
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28258
Salicylic acid_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0169922
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0544
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13377
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40105
Niclosamide (olamine)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0163864
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.2357
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32632
CRCGN014_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1907
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
MEOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80627
ZNF417	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94846
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99835
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.488
Starch and sucrose metabolism	KEGG Pathways 2026	1.0	null
alpha-1,4-glucosidase activity	GO Molecular Function Annotations 2025	1.0	null
Food allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1417
RASGEF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98537
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.846
Naproxen_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.016876
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.386
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0427
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_chimp_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S27_LF_C2_24h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88468
Dysentery	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
HEATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77979
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9375
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31071
MRPL57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Neck Pain Score 1	DisGeNET Gene-Phenotype Associations	1.0	null
Husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.65
ACTL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99393
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70972
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
TCEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71737
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91112
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56982
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.311
GSE94849_3_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88268
Duodenal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
Pericarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.297
PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-gene_name_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
SLC11A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49003
GSE109565_12_v_11_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7404
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91231
Dapagliflozin ((2S)-1,2-propanediol, hydrate)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.03154
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.1205
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73269
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82468
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
XPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81688
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.633
SFT2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06281
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9529
PRDM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51693
NFU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46613
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56753
ANAPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15227
Glycogen storage disease II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
POFUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.994
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94687
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.068
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.0451
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77875
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50502
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98237
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.80595
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
GSE196117_1_v_5_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Grb2-Shc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.69314
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93301
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8735
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.61025
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18441
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06417
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03979
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0519
ZNF512B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60523
Ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.731
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
MBOAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72352
Plant scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53074
Extracellular isoamylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.119
CC2D1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61403
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0688
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Plant parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
CRCGN014_HEPG2_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35538
MUS81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13617
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25098
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Medroxyprogesterone acetate_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0165898
Crypt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.502
Congenital sucrase-isomaltase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.41
Caryopsis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.922
ZBTB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73625
Prediabetes syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4918
GLRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91411
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96833
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
DV-90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
Clopidogrel_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0272147
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43547
RUNX1-22343733-PBMC-HUMAN-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9994
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54245
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29707
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62591
Ezz	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51255
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
REST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84617
CASKIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69487
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ECSCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59844
Dried cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
Bile duct cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
Sonidegib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0346218
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21798
MRPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10517
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
Zileuton_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0196152
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4557
Small intestine mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.742
CRCGN012_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05512
ARL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55874
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.54035
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79447
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86904
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1181
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.61728
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.73365
Pith	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1893
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7532
GSE137702_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76571
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47735
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11003700-pbio.3002240.s011.xlsx-MYCN-IMR32_RawData-Unnamed_2_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2057
PRKCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5802
ZNF747	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.774
Sieve tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
GSE175787_5_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.54728
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26721
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6984
RPS4Y1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47212
Glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.247
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
RAD51B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82938
PTPMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35432
Estrone sulfate (potassium)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0176868
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Binimetinib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0301728
Pravastatin (sodium)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0246222
RNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88738
RBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55584
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.76477
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70566
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9361
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8744
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.40429
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4339
NSUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60705
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7214
NAXE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85341
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MTREX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1884
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1741
TMCO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46299
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9288
PKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04834
Plant tumor tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.969
Middle lamella	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
Cysteamine (hydrochloride)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0151346
GSE158632_2_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
AHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73785
OLN-93 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
Gastrointestinal allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.013
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7236
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8084
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36672
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.78609
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95555
Plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.089
Pseudostem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38289
ACTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54897
[Ni-Fe] hydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.225
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.579
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84107
Selinexor _KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0169362
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12118
SKIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31651
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHISA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53993
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8793
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23769
RNASET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42158
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0951
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7508
Huelle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1038
DLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
SPTBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20678
MED13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47573
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30397
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40371
Relugolix_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0222973
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7759
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.366
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31037
TRMT61A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79567
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79252
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97547
Neratinib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0215775
Lactose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.893
1,5-anhydroglucitol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.13979
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3621
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92565
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35813
ACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74478
WDR53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.167
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98422
G cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.51735
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.786
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02859
Glycogen granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.435
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8761
CAB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76903
Digitoxin_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0330847
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32614
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
GroEL-GroES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
Gastric juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77188
Antral mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
CRCGN015_MCF10A.TP53.M_24H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32435
Irritable bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0054
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.9649
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38436
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
Glucosidase II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.515
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.48099
Cellulose microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63085
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.33
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9395
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.526
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4091
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4355
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5232
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7826
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12997
Jejunal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.627
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0591
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6799
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79108
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99951
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3516
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21778
NISCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53228
Pulp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
Tazarotene_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00955968
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
GSE188382_2_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.9702
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.754
LBH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77006
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.96465
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64058
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32494
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24783
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.86058
Honey	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.238
HMGXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70038
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.09365
Cobimetinib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0591668
HP1BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33954
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
Forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04935
Meloxicam_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0196979
GSE178340_5_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gemcitabine_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0232744
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4965
RAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43237
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
AKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34636
Goserelin (acetate)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0256019
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2581
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99758
ACP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06333
Busulfan_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0237589
HRT-18 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34505
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9824
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5216
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47288
Caco-2/TC7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.326
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2017
Hindgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
ZNF195	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61667
Villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.523
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9189
FKBP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65219
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1455
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Proprotein convertase 1/3 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
TBKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15091
Chaperonin ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56864
Camurati-Engelmann disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
BCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47916
Hairy root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47055
Intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.943
POLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68588
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1751
Juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.822
Fruit juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.605
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6467
Ray cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.211
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8261
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.07096
Woronin body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
TRAPPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17918
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.261
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7355
Sphingolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
PCDHB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81188
GSE210476_11_v_10_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CNTNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44786
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33955
Betamethasone dipropionate_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00968039
ZSCAN16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15186
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42862
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63888
PMC9510835-Table_2.docx-28-CEBPB_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Glossopharyngeal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
Microvillus inclusion disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35324
IGFBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82788
MINDY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99218
Gut mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08865
SKOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22509
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66454
ZMYM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51593
Functional diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46321
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4922
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3162
Autosomal recessive spinocerebellar ataxia 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.18227
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2185
GTPase activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.533
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80623
NBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36612
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51218
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11794
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Host cellular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
Riluzole hydrochloride_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0210914
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01472
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.042
Sporangiospore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.295
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95857
CACO-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
PMC12587232-DOM-27-6894-s001.pdf-18-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Phosphorylase kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.74
OTS514_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.015667
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
FAM83F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53553
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Econazole_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0399318
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4364
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62987
Pediculus humanus capitis infestation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.851
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.663
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01525
Congenital diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
GUSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42976
Hyphal tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.498
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0367
IGSF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97917
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1344
IFITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39771
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9579
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2955
Acute diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
GSE213588_9_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
C1orf159	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58835
Tuber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.402
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	90.9
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44483
H1-10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14438
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.10831
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08282
Immunoglobulin heavy chain amyloidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
BBLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85485
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45118
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.477
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.587
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7777
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84766
KAT6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59639
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.68699
alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
Vacuolar transporter chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9645
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0231
RTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07289
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66904
Intestinal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Cytarabine_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0292058
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Storage tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.60635
NR4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57559
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.633
STARD3NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
UNKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38826
Exocrine pancreatic insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
Periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.271
Xylanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96163
NPIPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50428
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.47883
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10891
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93004
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
Bicalutamide_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00739574
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6502
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29615
SLC22A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74698
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93347
ASF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03153
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73275
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1985
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77044
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97593
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07313
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
Golgi trans cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.9214
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5959
SSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99906
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.88951
DTP3_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0145775
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03256
GSE158632_3_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9326
THRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83834
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56421
DTX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20979
GSE158834_0_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSK1059615_HCT15	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.011478
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65091
Cytochrome o ubiquinol oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.702
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0756
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.1991
CRCGN011_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80605
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Aleurone layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.529
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94744
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.17847
Neratinib (maleate)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0193971
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
HCFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14239
Cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.531
ZNF738	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74262
Intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.811
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178340_7_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23395
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24291
GSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95975
TRIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7488
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.3145
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44561
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7265
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6578
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.88585
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23072
Tetracycline (hydrochloride)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.035232
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.634
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62577
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Phenylephrine (hydrochloride)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0129142
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2603
Phenytoin (sodium)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0199851
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50366
PHF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82669
GABRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99516
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
SMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74006
DNASE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70778
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.02645
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68956
PCGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90308
Pancreatic juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89646
ETC-206_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0167166
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24946
Congenital lactase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.2
r95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.842
NCDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.37055
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
glycerol-3-phosphate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.051
AKT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86097
Mucilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14764
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23322
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8345
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2323
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05811
CCDC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95118
Cecal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
JJ012 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2745
ML-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55058
chr7_142114588_A_C_b38	GTEx eQTL 2025	1.0	2.57785
Small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.386
XRK3F2_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0374925
KAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1603
Maltose transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4615
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28329
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17536
DNAJC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97685
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2564
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8553
CEP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.75812
Lucanthone_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0244882
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96397
OSBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68622
DUSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57228
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.96845
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36904
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39704
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.731
Berry	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.09
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60687
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.62321
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3057
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88996
olaparib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0289581
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5523
AJUBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
Trametinib (DMSO_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0270002
Carbohydrate digestion and absorption	KEGG Pathways 2026	1.0	null
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43286
ZNF157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98424
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50275
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62392
C1orf210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45569
GSE209973_1_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DHX40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22128
CDK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79561
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
LMX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52934
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
PMC12658036-41598_2025_25964_MOESM5_ESM.xlsx-Sheet1-Supplementary_Table_1_The_list_of_546_proteins_specific_to_pLV3-CMV-AR-TurboID_H2O2_group_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09969
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5425
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Microvillus membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FGFR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1536
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
ACAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29844
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.533
Tirabrutinib (hydrochloride)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0100518
ZNF554	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89233
TEAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19585
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1622
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.09165
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74504
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4016
PIGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25234
Vitamin K4_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0177621
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89655
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57435
ZNF396	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75907
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Glycogen storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
NSMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15958
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Antropyloric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SCRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83542
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2345
Glucose transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.671
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.774
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32979
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
Tranilast_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0082057
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2116
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13101
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9119
PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-Unnamed_0_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
Aspergillosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.7809
SYT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8566
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8708
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3043
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Omasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.452
archaeal-type flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.5
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87272
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14679
ATF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30312
CRCGN009_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65823
CCND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4374
Bestatin (hydrochloride)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0162639
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91322
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZW10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23988
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5579
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.19582
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perindopril (erbumine)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0208649
QTRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59371
GGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91359
Nipple	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
Cellulosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.28
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8215
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5745
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Docetaxel (Trihydrate)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0414868
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31735
Exocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78938
TAF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
Pralsetinib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0370247
GSE158834_0_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2256
ZNF37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23222
Anal canal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26141
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.527
DNAJC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37844
UBA52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03659
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.033
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32958
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72665
Enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.044
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
Harringtonine_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0190031
Norepinephrine (hydrochloride)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0210675
IER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35403
CRCGN014_HEPG2_3H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2313
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.42271
Intestinal juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67141
CRCGN016_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02954
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
ANG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04961
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93459
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.764
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.774
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03569
ZNF106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84613
CRCGN017_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24779
PTER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77138
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF562	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44809
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.587
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Benproperine (phosphate)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0199434
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6616
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81125
SAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1199
ARMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66715
AHR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8502
Hereditary spastic paraplegia 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
Gut cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.967
Pod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
Lactate (calcium)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0206698
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6084
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
SPG21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05892
GSE217552_3_v_4_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95286
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.31669
GSE213588_9_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83002
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6359
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5799
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0677
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41109
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51702
TFAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0784
CRCGN016_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0613
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6389
FADS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72995
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6784
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.58743
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.127
TM9SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84777
Giardiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6736
MGRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5081
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.85462
Pimozide_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0284715
GSE169152_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22615
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31066
ZNF786	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48806
Hyphal cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.513
PMC9558712-Data_Sheet_2.xlsx-POU3F4_WT_vs_CTRL-Unnamed_0_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
APOBEC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2701
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.77905
Pitavastatin (Calcium)_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0347694
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6146
Flutamide_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0165441
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49058
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6463
SETD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16358
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.67711
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dental plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
CRCGN017_MCF10A.TP53.M_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60815
Ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.795
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2925
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83291
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5987
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.774
NUDT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32856
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20041
Sunitinib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0110473
alpha-1,4-glucosidase activity	GO Molecular Function Annotations 2023	1.0	null
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39916
Hepatitis B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.7712
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2BC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62887
Rennet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.61634
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.25219
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32581
GSE94849_3_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
ZNF765	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98925
BHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27678
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7275
STOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60371
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8988
TPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30424
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.353
Fruit peduncle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05604
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08894
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9844
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37547
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76108
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02931
Oleic acid_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0270513
Cilostazol_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0218877
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2765
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.9948
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.347
Intestinal wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
Mild Adverse Event	DisGeNET Gene-Phenotype Associations	1.0	null
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55971
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08346
Jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.958
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0527
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39862
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7162
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2781
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41998
TYK-NU	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2622
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37348
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7707
Petiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74442
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39338
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77542
GSE178340_7_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Elagolix sodium_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0354363
GSE178340_5_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet4-RNAseq_SJIA_KD_up_inter_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1554
tm94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.316
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8248
JMJD1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01058
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.6164
DDX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05515
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89872
Small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.075
ZUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56553
ZC3HC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84653
ZNF876P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93129
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03993
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.77216
Delayed sleep phase syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7772
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92661
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.765
COQ9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43007
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Protein body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.95952
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75714
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9359
fungal-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.523
Formate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
ATAD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45112
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83727
Celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7005
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95438
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68995
CRCGN014_HEPG2_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03561
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.33202
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.63723
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89928
AT7519_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0360674
GSE185744,GSE185747_2_v_4_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32005
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64905
GATD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04696
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fenofibrate_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0308021
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2817
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21296
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12656
USP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21003
Lafora disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312