association	dataset	threshold value	standardized value
PDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33929
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34815008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06469
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K65934178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33714
BRD-K41355409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.359
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.3984
BRD-K38450726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04257
BRD-K70648728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34011
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20951
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27473
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16035
SCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53214
GSE158834_2_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34312
BRD-K73692505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24832
GSE130864_0_v_1_tincr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40432489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25259
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146865,GSE146866_4_v_3_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39238
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
BRD-K40558736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03853
Loeys-Dietz syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
GPATCH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3888
BRD-K50511447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53589
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_DMOG-Unnamed_16_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2846
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45774
BRD-A89681034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16098
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21367
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17188
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73296174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04632
BRD-K60080002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10705
BRD-K82409466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21483
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73994499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13272
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31490008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28312
BRD-K12782513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10539
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15355
SEC61A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63642
BRD-K50417536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56771
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2887
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Seh1-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A27844016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11691
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44012257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59742
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GOLM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22883
BRD-K54042694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13608
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
ARG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7088
BRD-K31372389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0179
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.4685
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56024445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30243
BRD-A60487173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61131
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92899
BRD-K00243272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06789
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42344
BRD-K39815998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46185
GADD45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39307
BRD-K16064200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73926
BRD-A09975616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13701
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79099
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
BRD-K53992608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06761
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09483
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31703
BRD-K90366266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04867
BRD-K52361779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15686
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
negative regulation of growth	GO Biological Process Annotations 2025	1.0	null
BRD-K72135530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01204
BRD-K30372674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38816
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8331
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K45893504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40064
BRD-K91655763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63203
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K82570855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04687
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80241
BRD-K43979194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62419
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41492504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14537
BRD-K69903198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55738
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1449
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3116
LIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56183
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K46439376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41383
BRD-K99971319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03018
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19114
BRD-K19103068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24293
BRD-K57969466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07885
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5428
RB-42-MC53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2101
CHMP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17951
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27287379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03649
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11679
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
BRD-K60295429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24798
BRD-K75037209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01307
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10010414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52919
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6058
BRD-K22778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4184
CRCGN009_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3252
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29384
BRD-K48332223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44288
GSE81803,GSE81912_4_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.966
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6302
BRD-K36855468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3392
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
METTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84647
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49457
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF569	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24899
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.138
ITGB1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03205
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28434
CAVIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95139
BRD-K60076175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17079
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34721572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06031
Deuterosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
BRD-K47083242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14658
GSE135514_8_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAMDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36846
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-KLF4_correlates_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05795
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57526
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07263
BRD-K06611347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37672
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K08504955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11628
BRD-K46607226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17546
BRD-K00401259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27132
regulation of cell growth	GO Biological Process Annotations 2025	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
BRD-K33371292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07431
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K02972160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10124
GSE84462,GSE84762_0_v_7_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A73618687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08488
CRCGN017_MCF10A.TP53.M_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3024
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12618
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of neuron projection development	GO Biological Process Annotations 2025	1.0	null
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0674
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.243
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09039
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebrospinal P-tau181p levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02936
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55011
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9498
BRD-K89992188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85614
BRD-K87158974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29511
BRD-K98519785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54718
BRD-K86109840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32467
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27762
EIF3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56231
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43496057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.81239
BRD-K85559506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38622
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13257316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28107
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9934
SDF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35187
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K66754362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69564
BRD-K45516283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03917
BRD-K00676343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14199
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09438
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K82521348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12091
BRD-K24081812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33399
BRD-K16560691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71391
BRD-K11696817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36031
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3235
GSE148692,GSE148695_7_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41324679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89236
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90191
BRD-K38370827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39948
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16095
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5198
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9937
PMC12586484-41598_2025_22484_MOESM2_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_DEGs_in_ATOH8-depleted_EVT_ATOH8	Rummagene Transcription Factor Associations 2026	1.0	null
Axon hillock	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
FXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68721
BRD-K01995700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56979
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68981
BRD-K39476596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22829
ANKRD33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99739
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4246
BRD-K94037108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42214
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77073
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5431
dihydroergotamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27421
BRD-K93186184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05386
BRD-K16885048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69017
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	4.79161
SEC61G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31311
PMC5691083-41467_2017_859_MOESM6_ESM.xlsx-FDR_0_1_RELB_RNAi-Unnamed_1_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1392
BRD-K66189308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13819
BRD-A29371732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46632
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6093
BRD-K50726251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20193
BRD-K95428783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02843
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K49338297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16501
GSE158834_7_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50985475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30847
CMTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20308
NAA38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83704
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16093
Adrenal cortical adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7455
CSNK1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52118
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94135
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46733
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K14645917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0297
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
GMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88218
BRD-K17659275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21539
BRD-K08199068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5173
BRD-K47999752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16515
BRD-K32595757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66329
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K82460510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45747
EKC/KEOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
BRD-K25773863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67329
BRD-K34456337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25101
BRD-K21927299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48456
BRD-K22390389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11552
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2479
TMCO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04447
BRD-K22800340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.94881
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41862
BRD-K80940089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5511
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.56
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0553
BRD-K10157835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57444
BRD-K83966071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16645
IRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03055
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXIII-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_breast_cancer_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
APOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81109
GSE70935_2_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A42536341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34259
OPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37821
BRD-K49529874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2226
BRD-K78120854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26745
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K92776249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92647
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89457
KPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46277
BRD-K26941844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28452
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184399_0_v_3_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K72379955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55817
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Retromer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.183
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17975
BRD-K54593730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06137
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135514_2_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38733341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1684
BRD-K10812033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03882
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K94790210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.39165
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33318
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09616
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72842
TOP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35777
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32106
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16857
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67263
UMNSAH/DF-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89453
GSE148692,GSE148695_5_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78041
BRD-K84517695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04631
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59108
BRD-K29301364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97084
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of protein ubiquitination	GO Biological Process Annotations 2025	1.0	null
GSE135514_8_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.057
negative regulation of intracellular signal transduction	GO Biological Process Annotations 2025	1.0	null
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50449
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16246
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6726
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48182
BRD-K32402344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04165
BRD-K79148949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20623
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98105
negative regulation of cellular process	GO Biological Process Annotations 2025	1.0	null
CRCGN008_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8377
BRD-K12984952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28563
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K56591923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07949
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81435
BRD-K82562625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03135
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01264
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1147
BRD-K21467089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24467
BRD-K45394633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91187
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-Overlap-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ACYP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02985
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5868
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38446773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33122
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
Human - Motor Cortex - Cluster - SST+ TH+ Layer 6 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2962
NMRAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7098
Endometrioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67430561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02583
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COMMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05983
Laryngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
GSE131649_6_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0493
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9683
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0407
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2398
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM238	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85763
BRD-K75073374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11536
BRD-K29458940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17632
CRCGN017_MCF10A.WT.HP_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00345
GSE179138_4_v_1_lama4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77023196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23625
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5051
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46332
LRPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23569
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25778
GSE147893,GSE147897_2_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:I14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02918
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cuticular plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46531
SIX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03367
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10573
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01288
BRD-K68512873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39571
BRD-K47143916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1696
BRD-K78902613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38678
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221004_3_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67245
BRD-K69269415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3553
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90516
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39288
negative regulation of protein ubiquitination	GO Biological Process Annotations 2025	1.0	null
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34293
BRD-K80622681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00383
ATPAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77699
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4385
GSE142684_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23997756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77943
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3148
BRD-K50260295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04102
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
IKKalpha-IKKalpha complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
CRABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58138
BRD-K56699877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87596
ZBTB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69712
BRD-K37584517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06334
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K55795421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16838
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
UBE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56256
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46219
BRD-K03440991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02688
GSE165647_5_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60462
BRD-K04969760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.72127
GSE111138,GSE111149_1_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
EYA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42097
BRD-K16167206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18984
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66008
BRD-K85636571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26034
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69466030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30751
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3181
ZNF768	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35164
ALDH16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06784
BRD-K42879623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.84892
SNAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05201
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62805
BRD-K82130737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0036
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68384
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.873
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09845
BRD-K43240808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20237
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35717
BRD-K40088786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09584
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19089
L2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43993
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3673
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5525
BRD-K21423945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54341
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE70499_5_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2846
TMEM89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94709
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K11095218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13676
RPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02867
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6099
IL13RA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71068
CLIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96199
BRD-K28764680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41694
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
IST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66054
BRD-K49666076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63247
BRD-K84178479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2929
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K15393664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09977
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88679751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05927
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46929
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBC1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23705
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXVII-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_sarcoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150634_1_v_0_cd28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97695
C2orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60171
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24946
BRD-K28656917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5961
LAYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2792
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17352
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	3.91336
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50445
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81969
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59712
VCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52806
BRD-K98625375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64739
BRD-K22474245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88706
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83132
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
BRD-K05444553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49191
BRD-K72807299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66192
t69-brown-adipose_male_2w	MoTrPAC Rat Endurance Exercise Training	-1.0	-2.22023
PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_CUTOFF_2_5_TOTAL-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
MTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13509
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.679
IDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79498
NFIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09165
SGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32608
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40251180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07194
PMC10361908-10120_2023_1395_MOESM7_ESM.pdf-33-ZNF565_ZNF565	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K66870022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48228
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54762
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06476
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41672
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72453
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
BRD-K08799663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18027
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89009
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Supplementary_Table_2C_Contrast_ATF4-def_DMSO_8h_vs_HCT116_DMSO_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
XPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63059
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
negative regulation of blood vessel morphogenesis	GO Biological Process Annotations 2025	1.0	null
BRD-K53491881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29223
BRD-K45222498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5562
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K90793170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27179
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61798
BRD-K01762107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88148
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07588
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146865,GSE146866_1_v_0_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7546
KDM4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7052
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HuH-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
tilorone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28625
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MBD3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05735
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01755
MRPL57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00591
BRD-K88645787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3498
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25239
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5819
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0699
BRD-K70518736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50598
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0475
ME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75585
BRD-K22185032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80876
BRD-K19036695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70437
BRD-K97462883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0336
BRD-K79355381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.00789
BRD-K35975002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31574
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18138
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
BRD-K63487554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65871
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07204
BRD-K11781871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03573
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K26402831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39205
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9288
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65873
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9045
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
BRD-K77965546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77001
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97962579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22669
NR1I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71105
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86914375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03614
G3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68524
HAUS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77891
T-24 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.1221
BRD-K48519079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04718
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_DMOG-Unnamed_12_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
FDFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2566
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXVI-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_prostate_cancer_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10423
CD47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32753
BRD-K13486159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71728
WWTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19063
BRD-K82145108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22304
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K85656316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51905
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K16268355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04589
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MCB-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.58
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03541
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_12_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6513
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K62692910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23777
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07236
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2295
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38559
dolichol-phosphate-mannose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.058
BRD-K69987634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44818
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of angiogenesis	GO Biological Process Annotations 2025	1.0	null
PMC6941881-mmc4.xlsx-IR_only_Up_DEGs-List_of_DEGs_that_are_upregulated_upon_PRMT5_KD_only_in_IR_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09114
GSE123689_1_v_0_cbx8_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62425
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85478
BRD-K41970046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28042
PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_UP_2_5-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47163
BRD-K68916730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83172
UBE2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47472
BRD-K71842353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12744
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K56912308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25412
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69837
GRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24073
DEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73116
Autosomal recessive nonsyndromic deafness 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
BRD-K30252238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02402
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42971210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11653
KHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13257
BRD-A35323217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87683
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00065
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0766
GSE110673,GSE110674_4_v_5_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35111
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K40358491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79535
BRD-K25559116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.97872
BRD-K23762204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23107
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TUBA1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96659
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13497
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16228
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25406
PLAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84554
BRD-K72255851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07632
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56608
BATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35152
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42448
BRD-K31010207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16347
BRD-K24246830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8834
BRD-K24554824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62214
ZMAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05073
MRPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53897
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K50718861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26848
GSE148514_0_v_1_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cob	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
BRD-A36428246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92549
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGAP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65677
PTPRZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58808
BRD-K23931095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63629
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K89574562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3776
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K85059356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50421
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.61338
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02571
negative regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97695
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1202
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
KLHL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31163
BRD-K68574010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26949
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67200393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39497
BRD-K46171140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00284
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4486
BRD-A17687311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21908
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04710685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03688
BRD-K12493093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63553
CDC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63376
BRD-K25484053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17219
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4879
PRR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27398
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37115
PIWIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19342
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF404	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37638
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
BRD-K77727343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51812
CRCGN011_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22355
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29703
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213632_1_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86872145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06913
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46088
BRD-K12612468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49369
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26292
ARAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14169
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21724
BRD-K47584662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02729
BRD-K64055457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4479
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6199
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73581966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2372
BRD-K27302831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2257
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213026
BRD-K25646425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76705
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4499
TMEM184A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27959
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04437
BRD-K01367715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16123
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3055
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K97445906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76283
BRD-K11925125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33244
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.72625
CRCGN012_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22099
RASGEF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93336
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50218
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20738
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.233
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.2189
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
polyhydramnios, megalencephaly, and symptomatic epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4827
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63733
aklomide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39121
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0148
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25056189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12047
BRD-K97343426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33924
GSE102342,GSE102648_1_v_2_curcumin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NOP56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16009
BRD-K12833024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04692
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47261271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09685
BRD-K88941096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.315
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84663394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78725
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27483
BRD-K56149020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06292
BRD-K47776393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3353
Thyroid cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
TP53BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36172
BRD-K36347292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26901
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
NR1H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.45965
NAA50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28522
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64904
STAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12537
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31021
BRD-K34595206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27499
BRD-K54861624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18246
BRD-K18978916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33074
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K57833824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19612
BCL2L12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.023
BRD-K06459664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87314
BRD-K44525591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07476
PTGIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84222
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30347
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97547
BRD-K64194889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25671
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89408
GMCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07043
BRD-K35326556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54326
Endomembrane system	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
BRD-K62979806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07837
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51914
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51054674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17395
SDHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80214
BRD-K47092271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60646
Response to fenofibrate (LDL cholesterol levels)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
negative regulation of cell growth	GO Biological Process Annotations 2025	1.0	null
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12298
BRD-K39237487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00926
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_H3K27me3-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BBLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51892
BRD-K56106571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08064
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8441
PSMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43125
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90034
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3497
BRD-K44743425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11099
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53889798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62169
GSE172490_4_v_1_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K29324759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20449
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A65592966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35907
BRD-K90094729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52854
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08825
BRD-K95729740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40045
MRPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88123
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64509
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0877
BRD-K57786075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08396
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38562
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0921
BRD-K58217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53733
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02702
BRD-K55018894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29784
BRD-K00078503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42602
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GID8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04607
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17675
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74515526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78585
BRD-K81220870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42412
GSE202134_0_v_1_rbm39_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22479
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45904306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14434
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67904
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.8576
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A76076412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12249
BRD-K91575768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13702
BRD-K57938735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22236
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
TNPO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66551
BRD-K26809097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38527
GSE233679_14_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K98008739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00733
BRD-K93310782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83361
GSE221004_3_v_0_prdm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95153427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3381
BRD-K68134791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.283
Keratoconus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
BRD-K19327124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76968
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SF3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4498
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86981519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0066
Frt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
BRD-K59772014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30428
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20069402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07058
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.641
SLC39A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57964
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38545
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65303
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
PMC3590650-bjc2012518x7.xls-Sheet1-Supplementary_Table_S3_list_of_predicted_target_genes_for_miR29c_present_in_both_PITA_and_Targetscan_predictions_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
chr15_79474452_G_A_b38	GTEx eQTL 2025	1.0	1.93399
SUMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24727
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85025
RWDD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33902
BRD-K32214429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17195
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30497
BRD-K74363294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29653
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25330450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16459
hydroxytoluic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25098
BRD-K50859531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24068
BRD-K69564473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00778
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4111
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K49707067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55584
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_SUZ12-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69903018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01226
BRD-K13049124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64422
BRD-K73430970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33895
BRD-K05251963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72393
BRD-K85294251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04148
BRD-K26826253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22269
BRD-K34158806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75283
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32426
GSE246461,GSE246463_5_v_0_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44722328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36865
BRD-A02612852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58816
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K65780164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59602
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7524
FOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15058
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41601
BRD-K79329532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.80111
MAP3K6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15098
BRD-K95792127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14434
ANTXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26454
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19227
ZNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50666
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06478
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07008
BRD-K13445266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17832
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9517
BRD-K84073439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2769
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
C2CD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56971
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5616
BRD-K98253383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59799
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12688
ATP2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00763
GSE130401_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal thymus morphology	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K63568016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52916
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02216
TMED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75274
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anaplastic large cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
BRD-K42799692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20996
CRCGN017_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6349
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08163
verob4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K43558307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16631
BRD-K98976117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23828
BRD-K90027990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54495
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.78285
BRD-K12396271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57265
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45815
EI24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43908
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56362
BRD-K26435104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49709
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K58237252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60717
CRCGN008_HEPG2_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1737
BRD-K13411423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2595
BRD-K53308623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72536
PMC11932929-41388_2024_3264_MOESM4_ESM.xlsx-p_0_05_FC_0_5_n_675-Differentially_expressed_genes_in_MCF7_AR-isolated_BCSCs_after_4_days_GSK591_500nM_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71872
GSE158834_12_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
negative regulation of angiogenesis	GO Biological Process Annotations 2025	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0532
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-NR4A2-sequence_name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
FRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12802
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57921
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34819
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02593
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31125
BRD-K30217326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17348
BRD-K45495792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01029
KLF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15139
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93899
BRD-K02024244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09129
negative regulation of neuron projection development	GO Biological Process Annotations 2025	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K61551386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27378
BRD-K51140037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2551
chr15_79420949_C_T_b38	GTEx eQTL 2025	1.0	1.4998
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_EZH2-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20879770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6367
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35685
CTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74448
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26309
CFAP157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48509
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11196699-41598_2024_61762_MOESM1_ESM.xls-Early_v_Normal-HES2_HES2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99331869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13039
BRD-K22002184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6072
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3501
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69678391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68363
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1771
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78175
BRD-K70851916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8684
BRD-K33770771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40866
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stereocilium membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.681
BRD-K49584388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6406
PMC8260791-41467_2021_24345_MOESM4_ESM.xlsx-NOT_MODULAR_GENES_DISEASE_LOCI-Gene_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56272400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01252
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K78196882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41599
SLC4A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03133
MARCHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58135
Multilymphoid progenitor cell_Umbilical cord blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02542
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF438	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43551
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7857
PMC10189495-mmc7.xlsx-TCF4_wk1-gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
YOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87353
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0669
negative regulation of cell projection organization	GO Biological Process Annotations 2025	1.0	null
BRD-K89652482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1152
GSE111660_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19073
GSE233679_12_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9106
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
BRD-K41334119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7212
CRCGN016_MCF10A.TP53.M_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13349
BRD-K50479239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25218
BRD-K44664883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22128
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K81956993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.2217
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
chr15_79548215_C_T_b38	GTEx eQTL 2025	1.0	1.68904
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9144
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25533
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89035
NSUN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60662
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98549
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48963
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K28559679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1139
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4162954-12864_2014_6430_MOESM3_ESM.xlsx-2102Ep-Genes_deregulated_in_2102Ep_cells_after_SOX2_knock-down_FDR-corrected_P-value_0_05_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65209
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXV-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_hepatocellular_carcinoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5868
BRD-K12340493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54639
RCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0268
BRD-K38984040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53838
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16936
PRDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72195
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K45732260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29463
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8239
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_pos_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60011
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K72787967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4529
PSMG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60783
BRD-K51364219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0033
BRD-K20110031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.00131
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03488
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59413
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15837
pravastatin-lactone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35349
mRNA cap methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43083
BRD-K68970089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18582
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3835
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
BRD-K74676765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54855
BRD-K41719231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54205
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70663
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4455
SLC25A24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34126
HSPA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47293
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46428124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21849
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
BRD-K32208085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63207
BRD-K73025852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34309
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24392
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40728
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9181
SCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29522
BRD-K04336022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68476
CFAP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30446
FAM162A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61364
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38315
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27582
BRD-K41323747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02377
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16264250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03911
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59564
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53796
TOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11769
BRD-K44141416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25822
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K38831170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15684
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6215
BRD-K18494310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37854
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2262
BRD-K57502201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64492
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17322
BRD-K27911943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04386
BRD-K97949309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21157
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36246
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0623
BRD-K74568359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37136
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A07870296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25885
ZNF80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64924
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
COX6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0839
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40915
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7452
FAM110D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96818
BRD-K81537454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12598
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161864,GSE161866_1_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
HECA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26637
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27498
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39178
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17592
GSE158834_7_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6305
BRD-K58193973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01895
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.64701
BRD-K61912055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92257
BRD-K76742876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49583
PMC12630751-41540_2025_602_MOESM2_ESM.xlsx-Sustained_Angiogenesis-KLF4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Mpf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84741
DLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10257
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
negative regulation of protein modification by small protein conjugation or removal	GO Biological Process Annotations 2025	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4109
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64204
BRD-K87889654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28367
BRD-K43918778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13431
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1185
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1049
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88505
BOLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44863
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33652
BRD-K03713632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42172
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62588
USO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02774
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49482
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BLTP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34461
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06967
BRD-K89668690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6623
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55443
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5357
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46428
BRD-K00263786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79418
IER5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95078
regulation of TOR signaling	GO Biological Process Annotations 2025	1.0	null
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
HSPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37791
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K02100640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12056
BRD-K79995507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28762
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95035301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01132
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67556876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12617
BRD-K97368902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79127
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1592
MAGI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09539
PRKACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33848
PMC10315050-12920_2023_1588_MOESM2_ESM.pdf-12-SKOR1_SKOR1	Rummagene Transcription Factor Associations 2026	1.0	null
SPRY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00544
BRD-K20829034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47646
BRD-K07551625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52969
CDKN2AIPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83279
BRD-K27885385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21574
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2619
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_DMOG-HIF2_-related_miRNA_targets_expression_during_hypoxia_based_on_micorarray_FC_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29162
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45359
POLR2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74357
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Laryngeal cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30861
BRD-K62263376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48863
BRD-K17062413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50972
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Oogenesis phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K18657361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0851
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06893
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.3081
FC-22-ZV65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217568
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13904
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6122
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07009788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24125
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24195
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	3.27567
TTC38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41001
BRD-K46623934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46289
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52731672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13004
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4674
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06981
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8094
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05653
BRD-K72351789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24797
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00677
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K33865795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90718
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ANXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66846
BRD-K88274759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05069
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
N4BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0693
NPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35045
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27055
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16449
BRD-K44622259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52237
BRD-K49211735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13991
GPR63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92711
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52527
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5192
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K17405621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84935
C12orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19347
BRD-K88831197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02817
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65153
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2894
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_pos_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
KLK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76703
BRD-K99727034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34157
GATOR1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.205
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33441
BRD-K13425292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12624
BRD-K54067431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01915
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.67879
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01882
hydroxyprogesterone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5813
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143847_2_v_0_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94921
PMC5390115-mmc7.xlsx-DE_Lists-H1-ECs_Experiment_2_H1-EC2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43074
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32191
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65637
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220520_1_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10803041-elife-86204-supp2.xlsx-Bulk_-_Snc-KD_in_HT-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08859
BRD-K73768826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32137
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87879912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31336
MESP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01087
PMC10189495-mmc10.xlsx-TCF4_wk1-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K61522760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42975
BRD-K38240683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00347
TRMT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12321
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53042
BRD-A79884839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85736
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8966
BRD-A35495382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08285
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM53C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1434
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78322
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68629
PMC10361908-10120_2023_1395_MOESM7_ESM.pdf-32-ENSG00000196357_ZNF565	Rummagene Transcription Factor Associations 2026	1.0	null
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61594
SPAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46281
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66039243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27512
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A63704386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96209
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6369
BRD-K47690679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22062
negative regulation of TOR signaling	GO Biological Process Annotations 2025	1.0	null
OSBPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20753
BRD-K22069962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95294
BRD-K56802897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49601
RRAGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25299
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6668
BRD-K86158100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27248
CDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4569
RPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57385
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28774
BRD-K51131084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16125
BRD-K05561348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48957
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38145
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00282
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44285
BRD-K64222382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54093
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06304
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82239
BRD-K15028515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.73362
BRD-K63504496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20154
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1162
BRD-K32018176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45454
BRD-K37680172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52889
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
BRD-K17020860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04355
BRD-K83902026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47645
BRD-K61021741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30708
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10637
BRD-K11487484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18149
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.5671
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82504
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128099,GSE128159_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76960970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57194
BRD-K72774661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9161
BRD-K75807319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43341
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77646
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101546_2_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
THAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54927
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K46619710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18818
GSE105170,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
PMC3728595-srep02327-s1.pdf-27-ZBTB1_ZBTB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0543
BRD-K94962942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41963