association	dataset	threshold value	standardized value
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5516
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22316
Pyruvate metabolism	Reactome Pathways 2024	1.0	null
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.314
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.47976
UK-5099	DGIdb Drug Targets 2026	1.0	4.411
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.963115
Interphotoreceptor matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.7389
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
single-organism transport	GO Biological Process Annotations 2015	1.0	null
single-organism intracellular transport	GO Biological Process Annotations 2015	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53289
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863447
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6879
pyruvate transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4353
Mitochondrial encephalomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
Fatty acid synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.098
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2206
PTK7_KD_GSE50138_675_human_H2009	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6008
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00844
TIM22 mitochondrial import inner membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1271
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
mitochondrial part	GO Cellular Component Annotations 2015	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9075
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6664
LC1SQSF	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99172
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57417
X-organ-sinus-gland complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.24
Plant parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
membrane	GO Cellular Component Annotations 2015	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25359
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4254
mitochondrial membrane	GO Cellular Component Annotations 2015	1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CMK115	CCLE Cell Line Gene CNV Profiles	1.0	1.72297
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.4831
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863447
MKN45	CCLE Cell Line Gene CNV Profiles	1.0	1.91
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905829
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
spleen	GTEx Tissue Gene Expression Profiles	1.0	0.841626
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863447
pyruvate transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9317
pyruvate transport	GO Biological Process Annotations 2015	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0763
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8442
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.064
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6624
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07137
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.49762
mitochondrial transport	GO Biological Process Annotations 2015	1.0	null
hsa-miR-636	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-509-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32926
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Biotin carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931758
Metabolism	Reactome Pathways 2024	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.186
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
Pleural mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
NCIH747	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59831
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9127
intracellular part	GO Cellular Component Annotations 2015	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26801
organic acid transport	GO Biological Process Annotations 2015	1.0	null
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.0029
42-MG-BA	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
PMC6591464-Table_4.xlsx-Sheet_1-Non-AIRE_regulated_genes_random_set_2_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84218
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09603
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949048
JHOC5	CCLE Cell Line Gene CNV Profiles	1.0	2.36415
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1248
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1229
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.33607
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6289
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0701
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
Lactic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.2093
hsa-miR-657	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1063
RPL39L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75658
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.39263
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10172
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.83377
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1755
T47D	CCLE Cell Line Gene CNV Profiles	1.0	1.57696
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8833
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.20584
ASIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0026
MITOGLITAZONE	DGIdb Drug Targets 2026	1.0	2.2055
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
U2OS	CCLE Cell Line Gene CNV Profiles	1.0	1.79788
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62101
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.248
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5795
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
Tricarboxylic acid cycle enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.478
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.1025
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47563
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9959
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78002
MELK_knockdown_150_GSE32873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.53507
GGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96437
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3848
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0299
HuCCT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0716
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.822
Bloodstream form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.95554
mitochondrial membrane	GO Cellular Component Annotations 2023	1.0	null
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886555
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905829
496100544_PCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.04478
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33959
NAD(P)H dehydrogenase complex (plastoquinone)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.662
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48514
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47101
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82502
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
COR-L311	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886555
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3665	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0491
Glutaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.283
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.3263
SQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67735
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4203
biological_process	GO Biological Process Annotations 2015	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21237
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41116
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35143
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8129
mitochondrial inner membrane	GO Cellular Component Annotations 2015	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.839
monocarboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6441
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2115
organic anion transport	GO Biological Process Annotations 2015	1.0	null
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.44911
HDQ-P1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35201
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5445
Phosphoribosylaminoimidazole carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3312
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0513
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1168
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.0133
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.956854
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.40421
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40902
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2777
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.6902
CMK	CCLE Cell Line Gene CNV Profiles	1.0	1.43473
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886555
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9393
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
Diabetic cardiomyopathy	KEGG Pathways 2026	1.0	null
KE39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54495
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04294
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	1.35086
hsa-miR-4418	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
pyruvate transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100296_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87335
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83214
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41038
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04284
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8254
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995847
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961346
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4118
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0166
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10172
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916627
Organelle inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11089
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1417
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5551
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.49795
organelle inner membrane	GO Cellular Component Annotations 2015	1.0	null
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00215
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3112
mitochondrial pyruvate transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Mitochondrial pyruvate carrier	InterPro Predicted Protein Domain Annotations	1.0	null
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.6203
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872739
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906508
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
anion transport	GO Biological Process Annotations 2015	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15427
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78938
TT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60912
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0609
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2658
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74508
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68207
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976896
Dihydrolipoyl dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.473
Trypanosomoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
Mitochondrial intermembrane space protein transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
NUDUL1	CCLE Cell Line Gene CNV Profiles	1.0	1.36776
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931033
mitochondrial pyruvate transmembrane transport	GO Biological Process Annotations 2025	1.0	null
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
KCL-22 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
Esophagus squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
organic substance transport	GO Biological Process Annotations 2015	1.0	null
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2321
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.03049
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.44078
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20989
Eyestalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3825
Glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.57
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09603
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01106
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61382
ZAPRINAST	DGIdb Drug Targets 2026	1.0	0.735167
carboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.1984
GSE149760_3_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44884
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.2181
SF539	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89004
NCI-H3122	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7809
mitochondrial membrane	GO Cellular Component Annotations 2025	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Retinal pigment epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25528
GSE201042_2_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79391
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41053
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7116
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.7877
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7276
monocarboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3746
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	2.09602
Aerobic respiration and respiratory electron transport	Reactome Pathways 2024	1.0	null
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.623
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.04885
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-NR4A2-sequence_name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5865
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52799
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	87.6983
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.57
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25528
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
single-organism process	GO Biological Process Annotations 2015	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.1481
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SNU308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46461
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.038
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
GSE239457_1_v_0_rasa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.705
fh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906508
Oxoglutarate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.461
ENTACAPONE	DGIdb Drug Targets 2026	1.0	2.2055
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mandibular organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2479
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5887
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.45821
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.56688
MFM-223	COSMIC Cell Line Gene CNV Profiles	1.0	2.15687
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3333
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.388
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Succinate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.318
KMH-2	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4145
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.24484
GSE161827_2_v_3_ertugliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Alevin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37052
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43426
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
not applicable_cell type comparison_GSE49439_365_human_podocytes and progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0873
hsa-miR-1205	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3512
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	133.075
NCIH1573	CCLE Cell Line Gene CNV Profiles	1.0	2.20946
cumulus-oocyte complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
ARNT::HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7019
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4788
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81177
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91548
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.5161
TMEM216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66677
13c4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.939
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01106
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5277
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.54289
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6992
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43544
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9656
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.0595
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9334
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1357
6-phosphofructokinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.451
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.087
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40607
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00025
Aa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13096
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0126
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905829
RPMI7951	CCLE Cell Line Gene CNV Profiles	1.0	1.6
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
Tongue cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100564_TCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12453
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20989
PC14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90667
Mitochondrial myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
LONIDAMINE	DGIdb Drug Targets 2026	1.0	1.7644
GSE241701_2_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.79284
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17857
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83214
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
496100561_PCx_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02313
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09288
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7859
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20989
membrane part	GO Cellular Component Annotations 2015	1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.81
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.93136
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46431
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mitochondrial pyruvate transport	GO Biological Process Annotations 2015	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72953
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9542
pyruvate transmembrane transport	GO Biological Process Annotations 2023	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84218
hsa-miR-509-3-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cybrid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34305
mitochondrial inner membrane	GO Cellular Component Annotations 2023	1.0	null
GSE95685_2_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Mitochondrial respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6064
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	57.9001
DANG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37153
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE169152_5_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09077
ion transport	GO Biological Process Annotations 2015	1.0	null
496100373_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15875
SNU5	CCLE Cell Line Gene CNV Profiles	1.0	1.60565
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10172
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.52805
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC2279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4938
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.69286
GSE153189_2_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5027
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39365
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00025
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6138
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4176
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3604
intracellular transport	GO Biological Process Annotations 2015	1.0	null
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39396
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.2162
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5191
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.03409
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
monocarboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886555
at1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
GSE153443_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6582
496100356_TCx_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.37348
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1543
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
PRC_DEPLETION_GDS3532_96_human_U2OS cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H650	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00844
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00844
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01106
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872739
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74106
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7166
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76555
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52369
cervix uteri	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7854
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172490_0_v_1_junb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE213632_1_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.931
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7908
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4628
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86378
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53899
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28026
GSE112860_3_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KP4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73599
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5248
mitochondrial inner membrane	GO Cellular Component Annotations 2025	1.0	null
organelle inner membrane	GO Cellular Component Annotations 2023	1.0	null
Respiratory chain complex II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.311
Mitochondrial envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SOX2_Deficiency_GDS4853_322_human_AZ-521 gastric cancer (GC) cell line - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
hsa-miR-1208	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Quiescent skeletal muscle satellite cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.03355
cellular_component	GO Cellular Component Annotations 2015	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0164
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17431
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chlorenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.1
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.2682
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.34618
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72717
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73897
EW8	CCLE Cell Line Gene CNV Profiles	1.0	1.94113
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906508
Pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.936
skein-like inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96052
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91743
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20989
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.301
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3557
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00025
Mitochondrial membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54122
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9576
transport	GO Biological Process Annotations 2015	1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4311
HNF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99249
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0361
ERO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35691
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NITROFURANTOIN, MACROCRYSTALS	DGIdb Drug Targets 2026	1.0	0.678615
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.382
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0