association	dataset	threshold value	standardized value
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	3.00169
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35194
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871166
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33335
BRD-K19220233_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-FX-A3TO-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K49371609_528116.cdx_A549_6.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09756
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.993894
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04204
KMS34	CCLE Cell Line Gene Expression Profiles	-1.0	-2.32679
RAD21	ENCODE Transcription Factor Targets	1.0	null
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66827
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916068
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854008
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5935
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15481
Thymus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.30644
BRD-U00779237_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
4371_KIAA1958_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.53734
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827343
BRD-K65602491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41821
spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885256
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.859724
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96919
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82344
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18601
BRD-K87399364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33397
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
16585155-TableS1	GeneSigDB Published Gene Signatures	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.941514
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5093
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.35222
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.7439
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-70-CU78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.585915
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.011
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884912
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100432_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30154
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.42068
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.98126
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2952
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:N18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12369
BRD-K72264770_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6863-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.98141
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983148
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.021
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13228
occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.52985
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7061
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K90686617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6512
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06287
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01259
ZBTB33_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73032790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16781
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.880229
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11144
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
HC-63-SV27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215872
BRD-K11636097_S1249_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13257
DD-85-WO51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313918
NCIH1436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74961
SNU410	CCLE Cell Line Gene CNV Profiles	-1.0	-2.73484
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.09266
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A18497530_EI-293_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6495
CRCGN015_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0256
Ink	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.812234
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.436408
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88542817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11438
BRD-K40816903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31967
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3316
BRD-K10435664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86644
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33021
WB-54-WD35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216595
FBXO33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62997
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCFL	ENCODE Transcription Factor Targets	1.0	null
BRD-K62970326_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99966
hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06456
BRD-K07825644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28215
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80663
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10305
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925413
RCOR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K17854062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43749
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0967
RSV_24Hour_19459069_GSE3397	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.74229
BRD-K55393423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4689
Rotavirus infection of children_Peripheral blood mononuclear cell_GSE2729	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.95864
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9804
BRD-K14909006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79127
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48953
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25375
HDAC2	ENCODE Transcription Factor Targets	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.97229
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260071
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.404
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00117
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKUT1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93242
BRD-K17421394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11582
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	2.37249
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65219
PMC9314667-Table_1.xlsx-Regulons-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888536
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44679
Cervical spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.892316
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07501326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08366
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-5.12655
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955666
16909099-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905054
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
BRD-K01734019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04211
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.949247
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7178_RBM48_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.609345
BRD-K43484052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27602
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.79824
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58498
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12842
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896402
CRCGN016_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06292
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.48459
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41652
CRCGN015_MCF10A.WT.HP_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13444
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.903227
SOX2_Deficiency_GDS4853_322_human_AZ-521 gastric cancer (GC) cell line - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CE-95-YX02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228747
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
deferasirox_homo sapiens_gpl570_gds3558	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12456
BRD-K98249237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25521
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.13605
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13228
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983263
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04618
H3K36me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32462
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	94.9284
TRIM28	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-7813-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99545815_HY-10459_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22872
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC-21-IP52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.429991
TGM2_KD_GSE23702_713_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44833
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67572
hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE240896,GSE240899_2_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42165
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13021
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42631
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
U-266	GDSC Cell Line Gene Expression Profiles	1.0	2.10089
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32237
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15691
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6039
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940522
GSE167474_2_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27477
UD-20-ER54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228026
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13988
BRD-K88070218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05545
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86541
H3K36me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84128
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41937
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YKG-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5578
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244796
BC-26-LE04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223649
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC33	CCLE Cell Line Gene Expression Profiles	1.0	1.64429
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-U00779237_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
9686_UTP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.670836
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-M16762496_S1205_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K92428232_HY-50877_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24663
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16647
17533364-TableS3	GeneSigDB Published Gene Signatures	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10826
CRCGN015_HEPG2_48H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3407
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40555
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47849061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01659
CRCGN017_MCF10A.WT.HP_24H:E18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0136
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.08543
ZNF732	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29054
MAP2K7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00380351
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52363
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211128_9_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.568
PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_HOXC6-gene_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13701
BRD-K11927976_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50845
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-01A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51398207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02929
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.60201
CEBPD	ENCODE Transcription Factor Targets	1.0	null
RS11846	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.92678
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.92191
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13494
BRD-K09468701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27997
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.20295
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7151
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04068
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04475
BRD-K96575636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08255
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865864
Perturb_12661_KD_RAB7_SRP017435	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.82331
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89801935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52113
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37582
BRD-K01896723_2-morpholino-N-((5-nitro-1H-benzo[d]imidazol-2-yl)methyl)-9-(thiophen-3-yl)-9H-purin-6-amine_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358668
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K01311880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00187
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.436
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996152
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5747
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54165
AD-43-XJ59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211499
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19499
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC138	DepMap CRISPR Gene Dependency	1.0	2.71199
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03888
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.89268
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.768229
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06357
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.899486
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL47	CCLE Cell Line Gene Expression Profiles	1.0	1.79387
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
19505326-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19307
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11208
GM2313	BioGPS Cell Line Gene Expression Profiles	1.0	1.13388
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.4387
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04828
BRD-K32280984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06727
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859072
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YE-46-YA12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272095
XC-65-XN91_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218487
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883258
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918659
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
BRD-K38380337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09117
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931225
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916837
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.66995
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70825
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872256
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.421
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01016
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.84702
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311595
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03229
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15045
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32777
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69219
2376_DROSHA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.560017
cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19608864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81212
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33710385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14768
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15048
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880273
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57351
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989561
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.59757
GSE111881_0_v_1_znf768_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32170456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16553
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876699
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0367
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29977
Embryonic brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.015
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.53097
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5566
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291359
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3622b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09427
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03565
REC1	CCLE Cell Line Gene CNV Profiles	1.0	1.77336
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901907
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19927
BRD-K44521151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23495
CB-46-FO63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262452
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.2692
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987437
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00337531
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905918
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.72452
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.05364
inner CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.852966
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.92189
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19981
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15499806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00154
6963_PWP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.673177
BRD-K72194126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26412
GSE211128_9_v_8_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cord blood stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
Prostate adenocarcinoma_PRAD_TCGA-G9-6373-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22457
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73272
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837683
BRD-K49050984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30452
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05371
GSE218727_0_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971405
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K64753899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97151
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11655
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.24957
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.4904
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02204
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.69988
ETS1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02911
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15505
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0555
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.990145
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K92468187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04933
BRD-K02118124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3619
GSPT1	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K17059629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20984
BRD-K01717817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22803
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15011
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24917
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.6701
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21658
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973321
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42035
NCIH358	CCLE Cell Line Gene Expression Profiles	1.0	1.56734
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.557261
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7893
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02149
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.932402
569_ASB8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.649251
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A68009927_daunorubicin_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K13289658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18386
GATA3	ENCODE Transcription Factor Targets	1.0	null
BRD-K19220233_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.39827
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86649
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
1843_CPSF4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.593207
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862647
BRD-K11859767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57305
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09271
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.51614
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38286
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13395
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44661
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945498
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JK-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9014
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K16554464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60809
SW756	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19575490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00758
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03826
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59316
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04049
BRD-K07307589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18468
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
colchicine-630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25069
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.26
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2388
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845001
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.422
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914494
BRD-K04468899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3686
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28839
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58665
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52594
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1171
GSE210476_2_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3155b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CRCGN008_HEPG2_24H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1566
ZEB1	ENCODE Transcription Factor Targets	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERCC4-ERCC1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.987
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.653869
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Monoclonal gammopathy of undetermined significance (MGUS)_Bone Marrow_GSE5900	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.59102
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11523
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.926243
PMC3023804-pone.0016344.s008.xls-S3_High_Confidence_PPAR_Peaks-Primary_Gene_Name_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04676
BRD-K34258713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29115
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17555561-Table2	GeneSigDB Published Gene Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.7512
GAMG	CCLE Cell Line Gene CNV Profiles	1.0	1.44428
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00974016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81003
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05273
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989038
GB-01-UN23_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28026
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46669
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975412
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A68009927_Daunorubicin hydrochloride_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79038
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.021
H3K36me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8183
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46723
BRD-K03287885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29324
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.19969
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15733
BRD-K14987634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49976
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2757-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K64862097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07033
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992076
ELF1	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03671
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46331
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885822
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1063
Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.66927
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	2.4835
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.2753
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6816
Lung adenocarcinoma_LUAD_TCGA-44-7659-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.937371
BRD-K13662825_dinaciclib_MCF7_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN013_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2734
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03671
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0696
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30158
BRD-K43384508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3662
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBALD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15774
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1286
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58974
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67177
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87909389_F3055_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900105
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89127
GSE154577_6_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957133
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP8	CCLE Cell Line Gene Expression Profiles	1.0	1.35596
BRD-K33869336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03477
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05191
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953509
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.5428
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67408816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97463
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60198
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85545
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21218
EGR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31563
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34682
BRD-K58214070_N-{3-[(2-Chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A02501536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01732
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07976
BRD-K47370004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2506
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_10677_KD_MTF2_SRP105765	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.55845
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08653
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9197
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2BK120ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15281
NCIH358	CCLE Cell Line Gene CNV Profiles	1.0	1.38223
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57999
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99739
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF274_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.89767
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.871909
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.49
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20909
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.16445
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06517
STAT5A	ENCODE Transcription Factor Targets	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.30652
CE-00-EK89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203948
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874951
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294432
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01914
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SX-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.9054
OD-96-OP94_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.601427
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.421
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50834
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04585040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05391
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48329
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870211
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02926
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97783
BRD-K03353688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68784
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19968781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66726
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
NCIH2887	DepMap CRISPR Gene Dependency	1.0	3.22264
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.5891
BRD-K58149231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22448
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.97582
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86839
UBTF	ENCODE Transcription Factor Targets	1.0	null
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K54233340_Dorsomorphin dihydrochloride_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28791
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.973544
BRD-A41250306_Cyclopenthiazide_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.18695
BRD-K17553044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9911
hsa-miR-3184	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT144	DepMap CRISPR Gene Dependency	1.0	5.25048
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21834
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7211
CRCGN012_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68554
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.048
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
albendazole-oxide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49726
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC12430004-ugae028_Supplemental_File.pdf-29-MKX_MKX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71533707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57828
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893254
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7872-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4815
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18695
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7263-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964534
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.679076
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45835
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59901
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880273
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52769
Rix1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.162
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.11722
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16492
BRD-K85722200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40633
Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860806
miR-142-3p_OE_GSE28456_470_human_Raji cells (B lymphocytes)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40955
ONS76	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63298
HLA-DRB5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00495615
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A431-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51835
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92888
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.26
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04115
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832127
OV56	CCLE Cell Line Gene Expression Profiles	-1.0	-2.2211
NCI-H1781	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960272
telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969685
PBX1	ChEA Transcription Factor Targets	1.0	null
SPATC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559386
GSE258991_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDAPCA2B	CCLE Cell Line Gene Expression Profiles	1.0	1.44652
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47811
BRD-K51087734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61507
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43389675_DAUNORUBICIN_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K90127324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20299
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.264
BRD-K06543683_Ro 31-8220 mesylate_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMAD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594542
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.55958
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.35689
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895226
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.43637
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32888
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5121-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4773
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.53276
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08236
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25443
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25542
BRCA1	ENCODE Transcription Factor Targets	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49128
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5252
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51466
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.904664
BRD-K74676765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21463
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JA-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987279
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45813
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.89318
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.96045
HMGN3	ENCODE Transcription Factor Targets	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829223
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.989421
BRD-K05799189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79431
PPARD	ChEA Transcription Factor Targets	1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.796588
BB-74-RX30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212924
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23002
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56821
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19363
BRD-K71590663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31468
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
11264_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.540522
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74961
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38706080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6095
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43319
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57064
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11606
15318932-Table3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K74148702_curcumin_NOMO1_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01861
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE202434,GSE202438_8_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19734
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47715
Lung adenocarcinoma_LUAD_TCGA-75-5146-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69650333_idarubicin hcl_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20974
CRCGN009_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39628
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91361836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34716
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945498
Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87909389_HY-10005_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02934881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23834
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10917
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34727
BRD-K19220233_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08111
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3825
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RSV_48Hour_22398282_GSE32138	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69219
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926809
GSE224131_2_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05328
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12151
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988226
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869401
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99220724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02954
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917262
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06308
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
BRD-K64072266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21917
BRD-K05737787_ISOEUGENITOL_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K36me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30379413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12079
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05456
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68149575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19295
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20215591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12412
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95678
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893628
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UA-39-TN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290258
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880273
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
BRD-K01045229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56196
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARVCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59273
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.25168
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221326
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17811
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE165548_2_v_8_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56662
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18068
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.894861
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.232
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920598
BRD-K21933068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18432
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.18725
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0062
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
GSE80537_0_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K27881972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03653
BRD-K62202988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23109
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5630-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06354
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-8250-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27543
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73069
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96214
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50053371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12055
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.78709
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03601405_NCGC00242337-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-3607-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55935
CRCGN015_MCF10A.WT.HP_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.35213
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22623
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21151
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K39244231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40771
BRD-K19699893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42129
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5888_NUP155_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.572838
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03232
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K00676343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94764
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62776
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860116
KDM5A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-342-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84759
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838732
LN18	BioGPS Cell Line Gene Expression Profiles	1.0	1.23161
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44861
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411379
DNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14536
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14515
PIK3CA_activemutant_56_GSE17785	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.10981
PAX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17762
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33949
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05305
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842141
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93425
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70112
BRD-U86222656_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CMLT1	CCLE Cell Line Gene Expression Profiles	1.0	1.602
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.59734
HT-144	GDSC Cell Line Gene Expression Profiles	-1.0	-1.94251
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357359
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.864814
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863713
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.12934
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13984
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851824
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16149312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.544
Follicular thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38279
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91585756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31067
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79432
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26644
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06635
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12278
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923488
BRD-K09117810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04654
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49154
BRD-K61522760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30281
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.387376
hsa-miR-662	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56526
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K30962012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08362
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.03854
RBBP5	ENCODE Transcription Factor Targets	1.0	null
BRD-A79465854_auranofin_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H-7-5941	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8518-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	2.59489
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21394
HB-24-GP45_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210441
MAP2K4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517861
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.849719
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.939017
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.491135
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00676
CRCGN015_MCF10A.WT.HP_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23958
BRD-K11636097_S1249_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80107
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35566
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.26
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11658
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31316
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989147
PMC6538380-elife-42374-supp3.xlsx-human-sp-ENSG00000007866_TEAD3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7355
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6199
Iron	dbGAP Gene-Trait Associations	1.0	0.036043
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4329-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.824469
BRD-K74148702_curcumin_HA1E_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K74148702_curcumin_SNUC5_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3477
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40577
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.898397
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.74862
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24647
AD-51-FB60_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17701
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04776
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03132
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OU-A5PI-01A-12R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89598
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89007
GSE188382_2_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871553
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49371609_528116.cdx_HCC15_6.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08609
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06836
Huntington's disease-like 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202622
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66641
LU-65	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53257
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38279
HEP3B217	CCLE Cell Line Gene CNV Profiles	1.0	1.45323
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64309
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08016
MM160113	DepMap CRISPR Gene Dependency	1.0	3.35365
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00135
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14174
H3K36me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948114
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.862261
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4917
GSE189941_1_v_0_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
DA-58-LZ09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229914
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.697084
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0593
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87670244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16903
BRD-K49103536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23488
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02076
Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE218098,GSE218099_1_v_0_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48454
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02901
LIVF001-008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55782
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21134
BRD-K96101240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70624
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892383
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04996
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901907
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.86481
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32154
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827168
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.21963
TMEM266	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600087
CDK2AP1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.0823
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32520360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09284
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05802716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19182
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PABPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01535
Null cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
TMEM181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06495
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20798
BRD-K95575699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2948
NUTM2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37261
BRD-K35863275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00252
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.899277
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30336
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26139
HOXC9	ChEA Transcription Factor Targets	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71713
CB-36-QH71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296542
GSE246660_1_v_0_lmo3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3189-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
IRF1	ENCODE Transcription Factor Targets	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49982
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55603
GSE210476_2_v_3_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0239
CRCGN017_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66785
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45514
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.919457
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18689
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	1.51269
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE167474_1_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56888
KD	DepMap CRISPR Gene Dependency	1.0	5.06857
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955958
BRD-K62236460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09006
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.57265
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24135
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.920232
4-PPBP	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26762
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GS-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SKOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73708
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6485
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48261
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833061
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26904107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14054
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21035
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941839
NCIH661	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62043
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	2.1194
PMC7806814-41598_2020_80145_MOESM3_ESM.xlsx-CombinedResults_TreatbySexMainE-Supplementary_Table_S2_Genes_with_significant_FDR_0_05_sex_by_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	2.54422
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846333
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846307
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.85
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREBZF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63315
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.56876
CRCGN015_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23513
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.05848
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00222
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.97681
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	1.38062
CIT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541629
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.45642
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14862
BRD-K13662825_dinaciclib_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79090631_CGP-60474_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-942	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33211
Prefrontal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.26
8227_SNRPC_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.562811
BRD-K17609687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75565
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237684
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	76.3779
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23138
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880273
BRD-K38519440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68158
BRD-K14763154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00532
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955534
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0624
protein binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K74300740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06723
CRCGN015_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8754
BRD-K06543683_Ro 31-8220 mesylate_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.97154
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45532
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05673000_Dicloxacillin sodium salt hydrate_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08826
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07688551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14358
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.941
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3841
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.355
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48178
calycanthine-1771	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03147
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82771
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07802542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26715
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901907
KNS-42	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51983
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SK-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9433
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4898
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945498
hsa-miR-3119	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K03351377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78037
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10725
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.18909
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17901
BRD-K19183365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75453
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A67788537_Salermide_A375_24.0_h_120.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K13007223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56107
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262558
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46552
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.829708
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08767
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837083
MEIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22049
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.2707
BRD-K27982554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15139
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42612
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13455
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22698
TEAD4	ENCODE Transcription Factor Targets	1.0	null
SMTNL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554143
H3K23ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AA-46-GL76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269506
HCC1897	CCLE Cell Line Gene Expression Profiles	1.0	1.77848
KMOE-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.15904
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836465
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.92658
GSE210476_9_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
no-10	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72801
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12443
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854418
BRD-K47348275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21749
LNCAP	BioGPS Cell Line Gene Expression Profiles	1.0	1.05825
KC-10-GC29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23657
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928677
Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC2808176__F1	PFOCR Pathway Figure Associations 2024	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5432
BRD-K46824282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28844
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308532
ZR-75-30	GDSC Cell Line Gene Expression Profiles	1.0	1.68764
BRD-K26304855_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906722
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13566078_HY-10518_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K54024474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25112
CRCGN010_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18432
SKMM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45432
ATF2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovary	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.972829
BRD-K32127177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25453
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876361
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.69278
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.537
BRD-K74148702_curcumin_PC3_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12371
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25593
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60478
BRD-K24825509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70994
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7167-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fetus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0264
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.61471
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP1S2	ChEA Transcription Factor Targets	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	12.2663
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15492
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.45
LIVF001-028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99345
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75547
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26417
ENL-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61134709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95447
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A75517195_thiazolopyrimidine_HA1E_24.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28804
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.42257
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61603
SNU761	CCLE Cell Line Gene CNV Profiles	1.0	1.35145
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05435
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.62095
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49704
BE-66-UB12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319984
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875317
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7421
BRD-K99277076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42424
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45709
BRD-K05246869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34572
BRD-K72745710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37006
BRD-K61829047_7b-cis_MDST8_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2835-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
BRD-K28347985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33074
PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01001
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84807
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87909389_alvocidib_HS578T_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.436
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8478
SBC-5	GDSC Cell Line Gene Expression Profiles	1.0	2.13513
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10671
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32637
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23265
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.730352
Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-10-RU23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257453
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74356
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.4466
SKMEL1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
NCIH23	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48608
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894655
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.2295
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MKN45	DepMap CRISPR Gene Dependency	1.0	2.11746
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOLT4	CCLE Cell Line Gene Expression Profiles	1.0	1.38036
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5838-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE107594_0_v_1_hmga2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
iron	GAD Gene-Disease Associations	1.0	null
LF-35-CP32_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364309
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55447
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
HC-76-HU27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404434
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SORT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0043516
SAP30	ENCODE Transcription Factor Targets	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.954735
BRD-A76490030_K784-3131_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98934548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25413
BRD-K03352270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4123
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08313
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.223954
BRD-K53814023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44432
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08344
ZNF93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29912
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00673
CDCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87035
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44067360_FLUFENAMIC ACID_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10826
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.837228
BRD-K01077691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03791
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.70469
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0544
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858563
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8141
EGF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0182062
BRD-K20542687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11414
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952349
STAT3	ENCODE Transcription Factor Targets	1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00135
BRD-K98169006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48426
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8021-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85266041_DNQX disodium salt_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19807
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15566
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2595
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20457
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:E09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20601
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K06974027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43821
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21876
BYSL	Pathway Commons Protein-Protein Interactions	1.0	null
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.597931
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
UMUC3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48232
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27591
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4027
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.12838
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_1_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K01896723_2-morpholino-N-((5-nitro-1H-benzo[d]imidazol-2-yl)methyl)-9-(thiophen-3-yl)-9H-purin-6-amine_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20653
SYNCRIP_OE_GDS1806_82_human_T-lymphocytes from normal donors were activated with anti-CD3 and IL2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1434
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20536
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45416
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02359
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2999-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77869064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13761
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO320	CCLE Cell Line Gene Expression Profiles	1.0	1.8279
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36764
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.2429
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
GSE215086_3_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4498
BRD-K59708864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47125
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.98902
CRCGN015_MCF10A.TP53.M_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06885
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15397
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	1.02706
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901907
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06462
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25461
CRCGN015_MCF10A.TP53.M_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41582
Perturb_6729_KD_jouvence_SRP288327	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IS-01A-21R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26061
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
NB5	DepMap CRISPR Gene Dependency	1.0	2.31941
hsa-miR-3155	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
JHUEM7	DepMap CRISPR Gene Dependency	1.0	2.51687
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27991
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04788
temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66846
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962329
gemcitabine_homo sapiens_gpl96_gse6914	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891898
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917221
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.91112
OB-06-WW76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334527
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18746
BRD-K30816563_Ranitidine hydrochloride_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49775
BRD-A54347351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40221
BRD-K34531548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21911
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36687
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0988
ART1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0044967
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834072
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PAX5	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76176797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24366
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82344
RL7	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.24903
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4712
GSE163240_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65392756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0157
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55976
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841833
SNU878	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85654
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4758-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.17602
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916944
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.02748
BE-27-RQ61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19516
BRD-K89638177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13374
EF-62-IO23_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224346
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.90642
CTCF	ENCODE Transcription Factor Targets	1.0	null
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56479
VNN3P	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00488668
BRD-K46171140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55333
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5808
NCIH520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58328
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865238
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10853
BRD-K74148702_curcumin_EFO27_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HS819T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52653
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03177
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64805
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34563
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.08063
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33767317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46511
GSE140651,GSE140653_5_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26847
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17472
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02461
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37588
BRD-K59960811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56951
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.613
BRD-A63949900_NCGC00238536-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
KKU100	DepMap CRISPR Gene Dependency	1.0	3.68428
BRD-K58044926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49744
Acute Myeloid Leukemia_LAML_TCGA-AB-2803-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75493
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25684
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	2.98905
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985506
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06079
CC-70-BD07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234777
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10371
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08618283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97099
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8368
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36044
BRD-K06543683_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31602464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13233
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22257
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K00853706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67232
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31616862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31841
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.26
H3K36me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20T-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.879584
BRD-K31883758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27624
7424_RPAP3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.535067
BRD-K19499941_STOCK1S-53863_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K57042334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06994
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847833
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cytotoxic T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.172
RH41	CCLE Cell Line Gene Expression Profiles	1.0	2.35863
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06797
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32857
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.42933
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57227
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00635
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68256
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345621
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K14166654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14114
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44161
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14553
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31813
BRD-K92158425_N-((5-chloro-1H-benzo[d]imidazol-2-yl)methyl)-2-morpholino-9-(thiophen-3-yl)-9H-purin-6-amine_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K85853281_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC12019345-41598_2025_98989_MOESM10_ESM.xlsx-Sheet_1-CCNE2_related_genes_AND_HNSCC_HNSCC_DDP_NOT_DDR_Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895227
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2202
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.93557
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9091
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE80098,GSE80366_0_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08538
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.834381
BRD-K11143221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32873
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K89524688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17901
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Heart_GSE9377_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37957
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K96740880_NCGC00182608-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K38494391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24165
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6999
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.435
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12254
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984218
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.57909
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37042
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79328
FTC-133 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28866
BRD-K03886176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32295
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906541
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87554
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K17953061_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00778
CRCGN008_HEPG2_24H:B05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6154
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34714
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22142
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924191
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90431
Liver hepatocellular carcinoma_LIHC_TCGA-T1-A6J8-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88274759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33964
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67394
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825639
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27298
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55603
STON2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527395
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K18190982_COT-10b_PC3_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.65593
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945498
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883638
BRD-K01754882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68799
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	2.22625
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.81431
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GI-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3074-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-OLIG2-M_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89311
GPR61	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542327
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.78986
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08888
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K34640380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2737
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07046
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57652
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
core of nucleus accumbens	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32331
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.26873
estradiol_homo sapiens_gpl96_gse4668	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10209
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	2.96306
BRD-K24978625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79078
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5517
Psoriasis vulgaris_Skin tissue_GSE6710	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.40317
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.24425
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.938123
Uterine Carcinosarcoma_UCS_TCGA-N5-A4R8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.277
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-70	GDSC Cell Line Gene Expression Profiles	1.0	1.83167
BRD-A78360835_cercosporin_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K72636697_QL-X-138_HME1_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08006576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29704
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K92776249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2545
K029AX	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6578
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87926172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25975
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18667080-TableS2	GeneSigDB Published Gene Signatures	1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30778
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF3_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
5550_NDUFAF7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.584135
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.01019
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T47D	GDSC Cell Line Gene Expression Profiles	1.0	1.59833
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.98667
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.762736
BRD-K73206088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00199
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
5198_MRPL15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.533902
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880542
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11259
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.617
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.908782
CORL88	CCLE Cell Line Gene Expression Profiles	1.0	1.55428
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.461
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31121304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25567
GSE154936_3_v_4_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19693
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27376
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30859
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3076
BRD-K11474067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2882
4108_IMP4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.541524
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEx Thyroid 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-7.10398
BRD-K47574423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14309
PPARD-23208498-MDA-MB-231-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CMK115	DepMap CRISPR Gene Dependency	1.0	2.33296
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.91712
3338_GEMIN7_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.09237
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UF-01A-23R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37657772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42949
Brain Lower Grade Glioma_LGG_TCGA-HT-7606-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.2937
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metronidazole-1921	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0658
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K57359365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5972
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
5748_NOP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.888534
PMC10820750-dmm-17-050487-s1.pdf-37-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K00615600_AG14361_MCF7_6.0_h_25.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3977
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944808
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851055
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3514
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33686
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32424
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8422-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KNS62	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55103
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-00-QG34_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433236
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16919
Stromal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20911
BRD-K35711197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0754
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47491
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.18363
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17859
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28894
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43964
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.470197
PMC11358472-41467_2024_51851_MOESM4_ESM.xlsx-Sheet1-Supplementary_Table_4_gene_expression_levels_for_323_genes_connected_to_EWS-WT1_in_JN-DSRCT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.957211
DD-89-WQ95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211795
BRD-K41538715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20328
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94975
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842206
GSE146982_4_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3634
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86759
BRD-K20039572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25086
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829515
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20619
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.82301
1197_CARS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.617868
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K99545815_HY-10459_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:E08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22403
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K99545815_HY-10459_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1765
GSE230174_0_v_1_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K15654812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30583
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM253	DepMap CRISPR Gene Dependency	1.0	5.07476
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H358	GDSC Cell Line Gene Expression Profiles	1.0	1.65517
LD-14-PB06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294172
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4968-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.613
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44P-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.13208
Sarcoma_SARC_TCGA-MJ-A68H-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1191
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98127
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02203
BRD-K67522096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17794
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931937
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.46144
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81104218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17168
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861655
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22276
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04377
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06086
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.0074
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05627
BRD-K50424430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87197
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.576223
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pineal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23872
Brain Lower Grade Glioma_LGG_TCGA-DB-A64Q-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11131
PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5194
Lung squamous cell carcinoma_LUSC_TCGA-39-5024-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4159
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12388
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51306
BB-55-JH29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264313
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19339
BRD-K12267335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03508
TCOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02189
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945159
6795_PRPF38B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.514482
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61123
BRD-K77681376_2-morpholino-N-((4-nitro-1H-benzo[d]imidazol-2-yl)methyl)-9-(thiophen-3-yl)-9H-purin-6-amine_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02881560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07923
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15737
PKN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47849
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81913
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.59545
BRD-K74568352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46165
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.51741
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.86533
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341296
Perturb_12294_KO_PKM_SRP322205	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912907
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69265
CRCGN017_MCF10A.TP53.M_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98021
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30534
BRD-K23112275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32852
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936346
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QO-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.22916
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.48267
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3434-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844807
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6433-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07813434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42547
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H8-A6C1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-A59174698_RITODRINE HYDROCHLORIDE_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.67717
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00219
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92735
BRD-M16762496_S1205_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.93362
BRD-A84941884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17835
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8459
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.57858
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovary	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-U08759356_EI-346_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-1227	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2746
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06797
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51873
BRD-K61223323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09028
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67188
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IP-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08716
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.67273
NCI-H2196	GDSC Cell Line Gene Expression Profiles	1.0	2.09623
HCC1806	GDSC Cell Line Gene Expression Profiles	-1.0	-1.97596
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06543683_Ro 31-8220 mesylate_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51764
BRD-A58269583_DEOXYANDIROBIN LACTONE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
7671_SBNO2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.851893
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54527
PIK3R2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OC-10-FB51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.671607
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09069
CRCGN012_HEPG2_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05043
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11333
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47785
BRD-K08899466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55326
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22366
BRD-K27026825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50408
NC-01-ET52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.573512
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76244
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1500	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19917
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857589
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3659
PMC4609150-13073_2015_228_MOESM2_ESM.xlsx-TP53-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21801
Avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.021
BRD-K43714461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06173
7427_RPF2_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.69936
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.448753
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00235
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885294
BRD-A60245366_AS-601245_SKBR3_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.192
CCNT2	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.22315
CBX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00458945
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.91634
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32093012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00896
BRD-K88746179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45579
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61548
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92036
BRD-K47511177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34702
GC-57-HV87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223066
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.16407
BRD-K53703060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03336
Lung squamous cell carcinoma_LUSC_TCGA-18-3409-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03507
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33204746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07365
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
CIITA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533408
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BA-90-AA10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241453
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	10.604
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32015
HD-18-YL30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22125
BRD-K26997899_D-64131_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13189
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471654
MAFK	ENCODE Transcription Factor Targets	1.0	null
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841071
BRD-K20690715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0131
BRD-K30895360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65324
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.537
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20826
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72308
BRD-K43674766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13533
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3528
8264_SOCS3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.677418
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01492
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43072
7657_SARS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.917519
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12075
BRD-A41451487_PK-11195_A375_24.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09023
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54416
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT-116 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.94403
CRCGN017_MCF10A.WT.HP_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.27396
ZFP64	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20731
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
NFKB1_01_167	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	9.26354
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26289
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37095
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38263
BRD-K33783177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2192
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH7	CCLE Cell Line Gene CNV Profiles	1.0	1.38954
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6593
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24566
BRD-K64593260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22043
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.69878
BRD-K09699976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10345
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19428
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.502391
RKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.202
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990517
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
risedronate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64984
LGALS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50205
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35121
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28729
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26133
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.9608
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15476
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990517
BRD-K00414849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42978
SLAIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00510671
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23681
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10398797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45605
CXCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00398997
Lung adenocarcinoma_LUAD_TCGA-38-4628-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	4.44273
MORF4 family-associated protein 1	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03548
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202597
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55217
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22329
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-M16762496_S1205_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875602
NCI H322M	BioGPS Cell Line Gene Expression Profiles	1.0	1.98132
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35456
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70567
CHD1	ENCODE Transcription Factor Targets	1.0	null
AB-71-CI37_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210337
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04016
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QT-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHUEM1	DepMap CRISPR Gene Dependency	1.0	5.96825
TSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04603
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81867
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.35547
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132408_0_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.32205
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.021
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NH-12	GDSC Cell Line Gene Expression Profiles	1.0	1.75324
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971012
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25908
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38331
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.13008
BRD-K02691653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24447
BRD-K28071390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15654
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01979
HDAC6	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4435
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31411
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20077
Lung adenocarcinoma_LUAD_TCGA-64-5778-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H250	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48016
BRD-K09607752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60816
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5194
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08423
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.7748
hsa-miR-423-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.43806
HOXB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71575
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	0.897868
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17695
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36317
BRD-A39093044_K784-3187_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34667
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.069
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926925
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8356
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07782
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26423
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.489
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924287
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5976-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326055
BRD-K12313989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12139
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K43909206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70621
BRD-K15269548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55022
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49055
BRD-K32471649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23344
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929441
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55601
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3464
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.931564
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.87872
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.04541
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00191
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66599
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16604
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11251
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24032
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
BRD-K72238567_656402-250MG_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.712
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A52530684_DOXORUBICIN_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46003
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29975
ZNF274	ENCODE Transcription Factor Targets	1.0	null
CAL51	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11798
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.503
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945643
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979792
BRD-K93210276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69495
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50352
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4617
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.19098
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.55042
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52796
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.295
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.85125
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
KNS62	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15231
ZNF263	ENCODE Transcription Factor Targets	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79222491_2-morpholino-9-(thiophen-3-yl)-N-((5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)methyl)-9H-purin-6-amine_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.36959
cotinine-1929	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIK3CA_druginhibition_57_GSE17785	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	3.07552
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3689_KD_NUF2_SRP352847	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.7795
BRD-K84178479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04837
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.59522
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41977
AD-51-FB60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322179
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57964
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828675
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WC-67-DI84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379346
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41205
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97339945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13545
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVTOKO	DepMap CRISPR Gene Dependency	1.0	3.12775
BRD-K02920459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07577
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.59846
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07898
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984304
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K55127134_fluphenazine_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
NB13	DepMap CRISPR Gene Dependency	1.0	6.63677
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11961
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
YWHAG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40639
Lung adenocarcinoma_LUAD_TCGA-86-8279-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-A34492468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18468
BRD-K01463939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65117
hsa-miR-491-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76143
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64382
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05852
BRD-K80296876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7843
Lung adenocarcinoma_LUAD_TCGA-64-1681-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.79747
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21372
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.66456
inferior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875704
CRCGN015_MCF10A.WT.HP_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.04054
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01332
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3944
WC-59-RG09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378236
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00197
NES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38013
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851204
embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.85093
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74314059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78185
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91634
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.88122
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8791
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8462
HEK 293T	BioGPS Cell Line Gene Expression Profiles	1.0	0.88443
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27542
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31476
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
11206_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.513844
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23528
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A17658676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08864
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.568
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96545
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50856
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32214
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05796780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03199
RT112	CCLE Cell Line Gene CNV Profiles	1.0	1.82788
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2771
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K30812092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32074
4950_MED27_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.605413
8332_SPC25_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.524005
KE37	CCLE Cell Line Gene Expression Profiles	1.0	1.40111
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37383
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-VT-A80G-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9677_KD_PIAS1_SRP295152	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.69663
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6005
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21765
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.8473
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9434
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300241
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12741
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_107_KD_STON2_SRP135729	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.86604
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4159-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67035256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32193
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21767
H3K23ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01787
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924572
SOX2_Deficiency_GDS4853_321_human_AZ-521 gastric cancer (GC) cell line - 18 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47945
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
SNU1544	DepMap CRISPR Gene Dependency	1.0	3.99717
BRD-K12384030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27111
BRD-K75497233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23573
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967041
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.952334
CRCGN017_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5103
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25126
CRCGN015_HEPG2_48H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06687
BRD-K03659510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79255
BRD-K97395479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11864
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BE-38-UW72_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310817
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.84851
BRD-K01095342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43141
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4769
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994616
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13533
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0302
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89803
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	2.22881
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5462_NAPA_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.829415
EW22	DepMap CRISPR Gene Dependency	1.0	2.04388
BRD-A16998493_etodolac_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05575
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50511447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27925
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.26
ZNF274_GM08714_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14823121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47262
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881041
Perturb_7218_KD_NOL9_SRP321650	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3577
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44866
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.828
CRCGN016_MCF10A.WT.HP_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9874
BRD-K06226868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9679
NANOG	ENCODE Transcription Factor Targets	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26524
MMP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31744
BRD-K26194226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37044
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93587
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.57374
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06995
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03231
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13858
BRD-K93496326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25791
PMC10879698-mmc1.pdf-12-MTF2_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30564
BRD-K38610362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2856
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53780220_N-((1H-benzo[d]imidazol-2-yl)methyl)-2-morpholino-9-(thiophen-3-yl)-9H-purin-6-amine_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87909389_F3055_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.70727
CC-90-EX35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231928
SNU16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48028
Lung squamous cell carcinoma_LUSC_TCGA-56-7822-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skbr3	HPA Cell Line Gene Expression Profiles	-1.0	-1.04303
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22023
H9	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57719
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55015
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28074
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33097
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98043
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.876215
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17751
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10528627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41937
HT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78816
PPARD-23208498-MDA-MB-231-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28633
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00502422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3103
BRD-M16762496_S1205_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863362
BRD-K78062244_STOCK1N-27488_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1214
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
HEC108	CCLE Cell Line Gene Expression Profiles	-1.0	-3.67918
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29071
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59525
NCIH2196	CCLE Cell Line Gene Expression Profiles	1.0	1.37518
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9136
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-1.06429
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81121
HEC50B	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02604
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.1412
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14327064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10632
BRD-K41006887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31888
Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.228
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01891
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.0822
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09511124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52727
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77820762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55804
AB-84-PK04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280535
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.449179
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF385C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13073
BRD-K74148702_curcumin_MCF7_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18667
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MQ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38256
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10151
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61H-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Osteoarthritis_Synovial Membrane_GSE1919	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.84118
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25829
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
A361	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.15119
BRD-K54233340_Dorsomorphin dihydrochloride_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91813
BRD-K44307624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41253
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.87659
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873898
STAT1	ENCODE Transcription Factor Targets	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7355
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.72134
Adrenal gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K22137463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54635
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3595
hsa-miR-4733-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01234
2793_EXOSC6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.504748
Perturb_5982_KD_YBX1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.771
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RL	GDSC Cell Line Gene Expression Profiles	-1.0	-2.60116
placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38074
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50352
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860494
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20322
G401	CCLE Cell Line Gene Expression Profiles	-1.0	-2.62349
CRCGN015_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0314
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15035
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40955
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPT1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530673
OVKATE	CCLE Cell Line Gene Expression Profiles	1.0	1.69735
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25211
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45317
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13118
USF2	ENCODE Transcription Factor Targets	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-A02333338_C3393M50_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10566
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5158-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36523261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6582
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08531
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9014
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7	GDSC Cell Line Gene Expression Profiles	1.0	1.53119
deferoxamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08297
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75942
CRCGN010_HEPG2_24H:D24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01614
GSE156708_1_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1484
CRCGN016_MCF10A.TP53.M_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46362
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40712
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05769
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31555
PA1	DepMap CRISPR Gene Dependency	1.0	2.06288
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.8135
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828668
SD-69-QA40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226742
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03665
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EOL1	CCLE Cell Line Gene Expression Profiles	1.0	1.35251
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
GSE234043_0_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SA-32-CC58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249189
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08476
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02325
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.40093
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14561
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.597515
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.83417
lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08076
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898456
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16537
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2161
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53396471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26957
8433_SRSF3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.660867
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92158425_N-((5-chloro-1H-benzo[d]imidazol-2-yl)methyl)-2-morpholino-9-(thiophen-3-yl)-9H-purin-6-amine_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41741
MON	DepMap CRISPR Gene Dependency	1.0	5.70346
BFTC-909	GDSC Cell Line Gene Expression Profiles	-1.0	-1.75293
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48555
hsa-miR-3919	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.70686
a549	HPA Cell Line Gene Expression Profiles	-1.0	-1.14999
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19244
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61836
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.43729
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927492
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12814
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910517
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14118
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A97730597_Hexylcaine hydrochloride_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28034
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957099
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867024
Lung adenocarcinoma_LUAD_TCGA-55-8302-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824848
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.71556
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.847542
Helper T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.192
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24699
BRD-K36807301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20179
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27564
BT483	CCLE Cell Line Gene Expression Profiles	1.0	1.57716
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988273
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68256
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-4705	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860784
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.880603
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.982524
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
7566_RRP7A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.575041
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99401
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45828
BRD-K89432538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20486
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_7_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1029
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14036
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4526	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
12734205-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862493
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	1.0	2.16589
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43341819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08292
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.031
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203-2004(H5N1)_7Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.28286
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826109
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MED13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15863
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06657
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901907
Epithalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.449288
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.20687
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06641
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30292003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88802
BRD-K04454173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13454
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67606
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37179
GSE193993_4_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962749
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42444
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66368
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80407
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420723
ZDHHC17	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.73929
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874317
BRD-K92991072_PAC 1_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K13016489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64062
BRD-K36815183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05299
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
16651414-Supp2	GeneSigDB Published Gene Signatures	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.70909
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02322
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09058
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.920985
BRD-U51951544_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18279
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0062
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.436
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35137
NFIC	ENCODE Transcription Factor Targets	1.0	null
PCTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13056
BRD-K15444511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18255
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-421_ChIP-Seq_H3K9me1_2_AR_differential_expression_upon_KDM3A_or_AR_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-5144-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855733
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.43304
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.17933
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE165307_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01016
Large granular lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.39358
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.924155
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.984112
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G6-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1693	GDSC Cell Line Gene Expression Profiles	1.0	1.48316
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25009
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.45596
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13118
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50095
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92221
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51624
ARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20064
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cisplatin_homo sapiens_gpl6480_gse33482	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844756
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31133
BRD-K28269391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43694
7527_RPS5_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.3068
BRD-A56592690_PX12_NCIH1694_6.0_h_30.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4994_METTL16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.53311
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06796
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39926
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00529794
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915655
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4315
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854546
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5729
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31133
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908146
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12868
496100641_PCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37492
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
BRD-K41327620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52486
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50177
BRD-K66089377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1182
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16126
H2BK120ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COL1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40608
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.979436
MYBL2	ENCODE Transcription Factor Targets	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28224
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17149
GSE212760_0_v_1_fxr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
OVISE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64436
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0594
NCIH1693	CCLE Cell Line Gene CNV Profiles	1.0	1.73719
MED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02392
Uroepithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.79075
KPL1	CCLE Cell Line Gene Expression Profiles	1.0	1.6798
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	1.46487
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993834
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90766
GSE240896,GSE240899_10_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.12993
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WE-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49371609_528116.cdx_HT29_6.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0471
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04309
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04785821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16935
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97764662_3044_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213747
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18783
BRD-K26304855_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64473
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93677460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19472
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929441
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57899
hacat	HPA Cell Line Gene Expression Profiles	-1.0	-0.942278
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945506
urinarybladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.886125
SMSCTR	DepMap CRISPR Gene Dependency	1.0	3.10661
LU99	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8903
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940364
BRD-K30258816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31958
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24416
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23413
BRD-A52530684_DOXORUBICIN_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0668
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66517
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22766
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94915822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37077
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895358
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC2808176__F1	PFOCR Pathway Figure Associations 2023	1.0	null
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05862
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22382
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15448
GSE204929_0_v_1_ywhag_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.67805
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10244410-41467_2023_39054_MOESM5_ESM.xlsx-PIE-LIN28B-GeneSymbol_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
VDR	ChEA Transcription Factor Targets	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5475
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.906974
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861498
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.103
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.29605
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EF-52-ML96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00111
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29571884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52717
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844166
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14724
GSE128333_2_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28016
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8183
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77471
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261607
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36056
BRD-K01614657_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6738
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1856
GSE175787_5_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71881549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3383
715_AURKB_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.4928
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24004917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10097
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76732
CRCGN015_HEPG2_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32943
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2874
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992553
emetine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80873
BRD-K34595616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03606
Amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.021
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00135
HCC1395	CCLE Cell Line Gene CNV Profiles	-1.0	-2.4129
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09172
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44602
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.26
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48455
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IH-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76005262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10881
BRD-K06543683_Ro 31-8220 mesylate_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.56402
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.90854
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.3075
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.01887
BRD-K99545815_HY-10459_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.932099
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2233
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07402
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01076
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-223	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-K74148702_curcumin_THP1_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.05941
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.70147
IRF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49137
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906177
BRD-K07274638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22153
IGF2BP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00376597
TTC709	DepMap CRISPR Gene Dependency	1.0	4.38682
BRD-K44921931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28961
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.63655
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75945
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68151
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04371
HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE203329_2_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.71645
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NUP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30744
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05777
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2443
BRD-K11636097_S1249_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C8166	DepMap CRISPR Gene Dependency	1.0	3.53232
GSS	CCLE Cell Line Gene CNV Profiles	-1.0	-2.70804
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A619-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.625836
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.13153
SIX5	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6003-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMA1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A11605036_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16783
CRCGN017_MCF10A.WT.HP_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13186
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04564
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908474
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epilepsy_lymphoblast_GSE7486	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.56616
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06356
PTPN11	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K07557785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0493
E2F4	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7474
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4761-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T5-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6954-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3023804-pone.0016344.s008.xls-S3_High_Confidence_PPAR_Peaks-Primary_Gene_ID_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parkinson's Disease_Substantia Nigra_GSE7621	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.48521
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11224
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14042
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835243
BRD-K19106745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21319
hsa-miR-4757-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895358
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08413
BRD-K41451401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65503
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K16195444_Oxymetazoline hydrochloride_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.601787
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04822
BRD-K02388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87346
metolazone-1932	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
BRD-K21680192_mitoxantrone_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
6708_PPWD1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.676137
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3756
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00367
NCIH2196	CCLE Cell Line Gene CNV Profiles	1.0	2.20361
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891835
BRD-K49371609_528116.cdx_MCF7_6.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0501
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06480376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39609
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17486
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17901
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912128
CRCGN016_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32571
GSE131660_1_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
epivincamine-1783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16006
BRD-K63921431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20079
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853223
GC-54-IZ89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296884
RT11284	CCLE Cell Line Gene CNV Profiles	1.0	1.38709
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RW-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.8974
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14707716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3814
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01025
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25226
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.37583
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.19615
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.04963
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
J7 hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.761
BRD-A60245366_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97183783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67755
CRCGN016_MCF10A.WT.HP_24H:D21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10694
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.62617
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.07023
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RC-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
5188_MRFAP1L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.544472
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906541
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10162
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36589
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.907479
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19220233_-666_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.546647
BRD-K05831864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57402
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04497
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	2.82157
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24314
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846793
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18017
BRD-K64827406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48998
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4361
CUX1	ENCODE Transcription Factor Targets	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.91938
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21851
TSNAX	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GU-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68608492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46353
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0369
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9946
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984826
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
3436_RACK1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.567714
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22045
GPR27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66196
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5947
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.9854
PMC11639743-mmc2.xlsx-LIN28B-gene_name_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MO-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.55169
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69769
BRD-K16891407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23968
BRD-A59985574_T542500_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARS-CoV_24Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.25267
Brain Lower Grade Glioma_LGG_TCGA-DU-5852-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60623809_SU11652_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9548
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40757
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.19123
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28886
BRD-K25064302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59998
BRD-K18787491_U-0126_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K16406336_METHYLENE BLUE_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48771
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K18352607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1055
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-01-FD24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3291
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62150807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11975
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
NFATC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07639
6-chloromelatonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23174
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
8656_TAF1A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.565666
SARS-dORF6_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.08357
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.04915
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77875023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.324
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K28598371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56786
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.36798
EST1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.04024
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28203
NB4	CCLE Cell Line Gene CNV Profiles	1.0	1.48894
BRD-A18497530_EI-293_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K43896262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47482
FC-62-AI14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284786
BRD-K51181201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75284
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33448511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30732
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.34471
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03651
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873704
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00135
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1083
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901328
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K38081867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39031
EGR1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997505
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89459
GSE156708_1_v_0_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.28823
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02284
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895358
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906541
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABI1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999466
BRD-K14813155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38991
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28463
CD-47-YL43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.537913
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0969
NCI-H28	GDSC Cell Line Gene Expression Profiles	-1.0	-2.33042
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.92864
GB-73-QS80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227942
NEIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14452
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.697958
CCC5	DepMap CRISPR Gene Dependency	1.0	2.59803
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03245
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.94349
Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U343	CCLE Cell Line Gene CNV Profiles	1.0	1.74935
BRD-K14695590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05126
SNU601	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13196
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18385869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.066
BRD-K60337438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26408
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34971
BRD-K03344897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28418
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9053
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZJ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.18487
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948114
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24895
nb4	HPA Cell Line Gene Expression Profiles	1.0	1.3229
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26855
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500356
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932934
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5782
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55936
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65488
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02776
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943953
BRD-K00610900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37271
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9619
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.91877
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4165-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
chr4_6695946_T_C_b38	GTEx eQTL 2025	1.0	1.0719
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71013
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76529
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16627
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31354456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26267
KNS42	DepMap CRISPR Gene Dependency	1.0	2.01441
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86272
EOL1	CCLE Cell Line Gene CNV Profiles	1.0	1.34042
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF3	ENCODE Transcription Factor Targets	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.68242
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85702
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8647_KO_GATA4_SRP287180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.2218
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18888
PMC6742760-41467_2019_12079_MOESM10_ESM.xlsx-Data_S8-Supplementary_Data_8_Target_genes_of_FOXA1-bound_enhancers_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C99	DepMap CRISPR Gene Dependency	1.0	2.78658
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49428
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0101
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.16343
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A43126523_NCGC00183690-01_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15816
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06291
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28612
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88775
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2121
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47962
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
SIMA	GDSC Cell Line Gene Expression Profiles	1.0	3.51855
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0088
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ionocyte cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10032
BRD-K24792153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09484
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.87
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7492
Sarcoma_SARC_TCGA-IE-A4EJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39495
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AF-12-IW93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.435265
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-2114	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.661
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04515
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904275
PMC9720390-Table_2.xlsx-Supplementary_Table_2-Supplementary_Table_2_Modulation_of_differentially_expressed_genes_in_groups_receiving_different_doses_of_FTC-TAF_and_FTC-TDF_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4312	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NCIH28	CCLE Cell Line Gene Expression Profiles	-1.0	-2.44232
BRD-K23975481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35036
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26749
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.826236
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08438266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50941
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26077185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02918
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RB1_KD_GSE50532_623_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68151
BRD-K09863466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67968
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853003
BRD-K35451051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05202
SPI1	ENCODE Transcription Factor Targets	1.0	null
GSE144453,GSE144454_1_v_0_tfdp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21182
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06003
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26632
BRD-K58971526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18289
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5846
CRCGN012_HEPG2_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22624
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09271
BRD-K18368161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.88904
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.981049
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58354
RL	CCLE Cell Line Gene Expression Profiles	-1.0	-2.90986
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
6845_PSMA5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.70217
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC22A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00691667
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38046
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15621
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMU1	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38170103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43422
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34712
MHHES1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78033
BRD-K01896723_2-morpholino-N-((5-nitro-1H-benzo[d]imidazol-2-yl)methyl)-9-(thiophen-3-yl)-9H-purin-6-amine_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JHOS2	DepMap CRISPR Gene Dependency	1.0	3.74695
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.015
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46567
MAFF	ENCODE Transcription Factor Targets	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13138
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.939693
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05129
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05671
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901907
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LNCAPCLONEFGC	CCLE Cell Line Gene Expression Profiles	1.0	1.51459
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08822
BRD-K03440695_Boldine_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GLS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.091
BRD-K43364707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09237
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901907
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983483
hsa-miR-412	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K98805845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32845
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01718
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49505
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33714
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE230174_0_v_1_dagla_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TTC642	DepMap CRISPR Gene Dependency	1.0	5.59353
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998638
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3359
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832302
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
CFAP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14008
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879734
limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE160304,GSE163392_0_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
M14	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.03937
BRD-K04706894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54432
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31504
BRD-K10846167_N-((1H-naphtho[2,3-d]imidazol-2-yl)methyl)-2-morpholino-9-(thiophen-3-yl)-9H-purin-6-amine_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07138
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12043227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10565
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850284
Prostate adenocarcinoma_PRAD_TCGA-G9-7519-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E6-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3438
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7477-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882367
MZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855087
binding	GO Molecular Function Annotations 2015	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74148702_curcumin_HCC515_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3385-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82922
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3122
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07226
HS729	CCLE Cell Line Gene CNV Profiles	1.0	1.66896
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39471
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56667
Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64800655_HY-11001_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981406
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72629
heart	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Fetalbrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.957552
OC315	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4768
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51016
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-U07653185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33015
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K88573743_A443654_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70612
Genital mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34852
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8698
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865603
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57609
BRD-K06181307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0062
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37342
Lung squamous cell carcinoma_LUSC_TCGA-58-8390-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L363	CCLE Cell Line Gene Expression Profiles	1.0	1.35345
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44489
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.997836
hsa-miR-1291	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
U343	CCLE Cell Line Gene Expression Profiles	1.0	1.82265
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.7797
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50836
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.864469
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863429
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86102179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06153
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01237277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79241
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.949597
hsa-miR-3660	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4011
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31122616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42401
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.78565
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77128
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880273
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932687
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.21259
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.20084
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.232
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21746
BRD-K41306114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05106
ATF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.61521
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23085
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38637
Prostate adenocarcinoma_PRAD_TCGA-CH-5754-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.99819
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27613
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25496
AD-51-FB60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255034
RXF393	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.893306
Lung adenocarcinoma_LUAD_TCGA-49-4507-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CVB3_9Hour-Infection+U0126_None_GSE697	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71565
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35819
SMC3	ENCODE Transcription Factor Targets	1.0	null
BRD-K12325488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06445
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04897
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.77251
CHD7	ENCODE Transcription Factor Targets	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849868
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.894898
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.986355
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23403
GSE160001,GSE160670_1_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13838
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18547
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PI-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.474337
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.658827
BRD-K87602457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75334
BC-84-BQ58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328295
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01494
CHLA57	DepMap CRISPR Gene Dependency	1.0	5.56605
TCERG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08236
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05961
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34492
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5UA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6441-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34603
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18629
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.825469
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946836
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49615
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A13122391_16-HYDROXYTRIPTOLIDE_MCF7_24.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K40117723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05365
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32077
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18607
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29648
MORF4L1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37313
ABCB11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00550757
TCF12	ENCODE Transcription Factor Targets	1.0	null
BRD-K04143388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06093
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.949545
Pancreatic adenocarcinoma_PAAD_TCGA-M8-A5N4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.2993
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830472
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
EW-7	GDSC Cell Line Gene Expression Profiles	1.0	2.12175
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56731
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
SARS-dORF6_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.34124
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23063
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
HCC1419	CCLE Cell Line Gene Expression Profiles	1.0	1.3604
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08108
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24647
18667080-TableS9	GeneSigDB Published Gene Signatures	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77934
SH10TC	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10251
BRD-K43389698_BMS-387032_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.981702
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02814
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40789
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954715
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61220632_LEOIDIN DIMETHYL ETHER_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1263
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38630090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41603
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37033
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45684
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14482
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-M16762496_S1205_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89515752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01393
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	1.0	null
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.553168
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07641
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25737009_-666_A375_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886969
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78409
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28224
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.841935
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	3.07479
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AA-48-XT80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.572969
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849131
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66363
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.05065
BRD-K67352070_TC 2559 difumarate_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K94761446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47757
Raji	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53531
SJSA-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41557
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132408_1_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	101.344
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.471
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.82124
BRD-K75784474_NCGC00188012-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K53489056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19592
AIFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28989
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832302
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.03155
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.832251
2561_EIF4A3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.598802
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.954341
HTT	Pathway Commons Protein-Protein Interactions	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211151_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K92158425_N-((5-chloro-1H-benzo[d]imidazol-2-yl)methyl)-2-morpholino-9-(thiophen-3-yl)-9H-purin-6-amine_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
MJ	DepMap CRISPR Gene Dependency	1.0	2.64103
BRD-K50434315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01904
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31947
hsa-miR-3622a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37592272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2254
BRD-A78360835_cercosporin_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
RBM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11444
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74714
BRD-K18533510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06379
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
G-401	GDSC Cell Line Gene Expression Profiles	-1.0	-3.53725
PMC6683136-41598_2019_47363_MOESM2_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1-AS1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04513994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61268
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.906144
8856_TFR2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.533606
KMS11	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5807
MAX	ENCODE Transcription Factor Targets	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55453
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845293
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866845
BRD-K53414658_-666_RMGI_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE239844_1_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.07918
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05773
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TF-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38928
BRD-K65955264_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47556
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MG-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43447
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19694
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.96656
BRD-K49401787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01908
IA-LM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90997
BRD-K10180613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07131
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22831
BRD-K15690866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17687
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04534322_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20065
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.931235
BRD-K95147502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11427
cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
4940_MED18_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.526168
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0902
BRD-K82364958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26044
ranitidine-1404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25713
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852299
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.232
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01392
Sarcoma_SARC_TCGA-LI-A9QH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948841
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
FADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24445
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE70	CCLE Cell Line Gene CNV Profiles	1.0	1.52054
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.867912
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_10_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20758
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79978
E2F6	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00654
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.32532
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.16019
MCIDAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4735
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990646
5518_NDC1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.510556
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0397
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.30509
DA-10-HD17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322508
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20974
XC-12-SL04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281302
H3K36me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
NPIPB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28883
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOTN1	CCLE Cell Line Gene Expression Profiles	1.0	1.60619
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853223
BRD-K80462316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10566
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.8459
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24167
BRD-K32828673_Chelidonine (+)_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K45860594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52105
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911808
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K49371609_528116.cdx_HEPG2_6.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34155
BRD-K44328896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68968
GSE182854_2_v_0_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03509
CRCGN010_HEPG2_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0399
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.97775
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.87935
Brain Lower Grade Glioma_LGG_TCGA-KT-A74X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28429328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24803
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A03898562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02082
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20560768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24525
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ED-71-GA72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.486071
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59099
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-GH-A9DA-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50737
DISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40494
SNU216	DepMap CRISPR Gene Dependency	1.0	2.9765
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.06628
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44988
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2_Deficiency_GDS4853_320_human_AZ-521 gastric cancer (GC) cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE211128_4_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T4C_BATF3_downreg_padj_0_01-Gene_Name_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31485
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4005
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26449
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.73439
BRD-K10412976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38135
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14887
BRD-K19526797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74974
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.396111
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRY	JASPAR Predicted Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1X3-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49096
PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05725
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62926
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07982814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39538
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83808
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.83013
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYP4V2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612864
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15703
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Huntington's Disease_Blood_GSE1751	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.68015
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241284
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08576275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35848
16288205-GeneTable3	GeneSigDB Published Gene Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A4SU-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26488
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20028052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21282
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.16514
EST1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918767
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZM-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
BRD-K74148702_curcumin_PC3_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNUC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73709
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SS-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A03684405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12977
7515_RPS26_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.643684
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04934
BRD-K93697231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17033
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Natural killer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12295
BRD-K38972344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08505
BRD-K36883526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08588
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05774
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9411
Lung squamous cell carcinoma_LUSC_TCGA-68-7757-01B-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01861
BRD-K48046422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35396
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16186
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918204
Sarcoma_SARC_TCGA-SG-A6Z4-01A-22R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193993_5_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.11407
Lung squamous cell carcinoma_LUSC_TCGA-33-A5GW-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69879051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32906
BRD-A76904477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3271
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.985654
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04734
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6993
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-A60245366_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCK81	DepMap CRISPR Gene Dependency	1.0	4.23841
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.015
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1348
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4323	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K13146924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0175
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13988
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ARHGEF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601401
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03511
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.994018
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.95564
BRD-K20600965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11016
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_18438_KD_NR2F2_ERP124128	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC2866657-pone.0010547.s003.xls-ESE3_corr-Genes_correlated_anticorrelated_to_ESE3_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.14477
HS695T	DepMap CRISPR Gene Dependency	1.0	5.82016
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5907-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SUPT20H_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49348
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85876
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SYK_druginhibition_283_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.15903
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4937
BRD-K04614055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17417
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25181
POU2F2	ENCODE Transcription Factor Targets	1.0	null
NPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35045
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	1.0	null