association dataset threshold value standardized value GSE148066,GSE157787_11_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8CD-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE200352_5_v_8_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null Entorhinal area, medial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43766 COLO201 CCLE Cell Line Gene CNV Profiles 1.0 1.40973 GSE126345_2_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pituitary GTEx Tissue Gene Expression Profiles 2023 1.0 2.03982 superficial stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82929 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R53T-0926-SM-3GADH GTEx Tissue Sample Gene Expression Profiles 1.0 1.08644 RCOR1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6659 ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.9496 STAT1-17558387-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_10707_KO_RbpJ_SRP354352 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 occipito-temporal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07839 all GWASdb SNP-Phenotype Associations 1.0 0.030311 Dbf4-dependent protein kinase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.866 posterior part of anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18861 GSE137914_0_v_3_tet3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.977126 ITGA7_OE_GDS3209_142_mouse_skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_14896_KO_H13_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.98137 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.31465 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42145 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93191 r4 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82686 GATA2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70392 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.7174 Ventromedial hypothalamic nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09491 oral mucosa HPA Tissue Protein Expression Profiles 1.0 1.03283 CORL311 CCLE Cell Line Gene CNV Profiles 1.0 1.34751 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I4-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A6BH-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Satellite glial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.961 Acute Myeloid Leukemia_LAML_TCGA-AB-2939-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NPJ8-0011-R9a-SM-2YUN5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37467 Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2814 CCLE Cell Line Gene CNV Profiles 1.0 1.553 Nfe2l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.051 GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.09926 GTEX-OHPL-2526-SM-3MJGT GTEx Tissue Sample Gene Expression Profiles 1.0 1.25214 ZNF384 ENCODE Transcription Factor Targets 1.0 null GSE112174_5_v_7_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.891889 YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24217 Anteroventral periventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24064 ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6652 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.80774 TBX2-33478486-IMR90-HUMAN-LUNG ChEA Transcription Factor Targets 2022 1.0 null ventrolateral part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02661 SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.03033 intermediate stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0469 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.49643 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.28306 GTEX-QLQ7-0726-SM-2I5G2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01612 PML ENCODE Transcription Factor Targets 1.0 null Tfcp2l1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 60.7585 GSE248045,GSE248046_6_v_1_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.82038 SDHAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79703 r6 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83051 NCIH1651 CCLE Cell Line Gene CNV Profiles 1.0 1.43169 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1657 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.827539 MYOG_myocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dermatome TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.603 GSE203158_1_v_15_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE242647_2_v_3_adiponectin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12479 GTEX-R53T-0826-SM-48FCP GTEx Tissue Sample Gene Expression Profiles 1.0 1.92794 GSE179031_0_v_2_foxp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00466 superficial stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.05419 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34452 GTEX-XUJ4-1526-SM-4BONU GTEx Tissue Sample Gene Expression Profiles 1.0 0.857542 Artery - Tibial GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.578353 GSE193258,GSE193259_9_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE129725_4_v_0_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null mantle zone of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13067 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.979249 Integument TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15708 smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.078587 GTEX-PWN1-2026-SM-48TD9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.29614 GSE211177,GSE211178_0_v_1_ets1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null eGFP-GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31405 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lamina propria TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.478534 H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE131798,GSE131804_1_v_0_igf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Rif1_KD_GDS4943_242_mouse_J1 embryonic stem cell (ESCs) line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Basolateral amygdalar nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27814 HUG1N CCLE Cell Line Gene CNV Profiles -1.0 -2.72615 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null supramarginal gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.890984 OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5487 CD68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95111 TCF3 ChEA Transcription Factor Targets 1.0 null CEP250 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80918 PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GSE210101,GSE210114_5_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S32W-1426-SM-4AD66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35769 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3303 GSE216273,GSE216292_0_v_1_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE224096_1_v_0_cocaine_human RummaGEO Drug Perturbation Signatures 1.0 null Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TRIM28_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE135030_3_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE186440,GSE186443_0_v_5_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null J82 CCLE Cell Line Gene CNV Profiles 1.0 1.40515 GSE192689_0_v_2_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null periventricular stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61549 GATA1 ENCODE Transcription Factor Targets 1.0 null GTEX-XXEK-1326-SM-4BRV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52751 EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-1326-SM-4LVMN GTEx Tissue Sample Gene Expression Profiles 1.0 0.940185 SW 780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41327 GSE111660_1_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Mas-related G protein-coupled receptor family InterPro Predicted Protein Domain Annotations 1.0 null SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null UBTF ENCODE Transcription Factor Targets 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.834412 Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918719 MYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2695 PML_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 144.771 parathyroid gland HPA Tissue Protein Expression Profiles -1.0 -0.721457 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56861 superficial stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3737 Heschl's gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.5278 GSE190316,GSE190324_10_v_9_rbm4_human RummaGEO Gene Perturbation Signatures -1.0 null Neurod2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 52.6367 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7914 PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HA1E DepMap CRISPR Gene Dependency 1.0 2.30353 GSE93309_2_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE181966_0_v_3_has2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SP in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.985552 H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null UNC5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02985 GSE119564_1_v_0_zfp217_mouse RummaGEO Gene Perturbation Signatures 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.73046 GSE168797_4_v_0_cannabidiol_human RummaGEO Drug Perturbation Signatures 1.0 null Large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 anteroventral periventricular preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19814 cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null GTEX-XV7Q-2226-SM-4BRVY GTEx Tissue Sample Gene Expression Profiles 1.0 1.3103 Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13446 GSE206729_4_v_1_trps1_human RummaGEO Gene Perturbation Signatures 1.0 null DNM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81683 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB7A ENCODE Transcription Factor Targets 1.0 null LK-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WEY5-0826-SM-4LMIH GTEx Tissue Sample Gene Expression Profiles 1.0 1.4735 salivary gland HPA Tissue Protein Expression Profiles -1.0 -0.721457 GSE96641_1_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.4605 TEAD4 ENCODE Transcription Factor Targets 1.0 null subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04304 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CTCF_MEL cell line_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-2926-SM-3DB77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.913351 GTEX-T2IS-0011-R11A-SM-32QPC GTEx Tissue Sample Gene Expression Profiles 1.0 0.988535 RNASE7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59858 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957186 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.941377 GSE178255_2_v_7_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null ADA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17162 g-protein coupled receptor activity GO Molecular Function Annotations 2015 1.0 null Perturb_2187_KO_Map3k7_SRP237503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.60991 cell part GO Cellular Component Annotations 2015 1.0 null GSE162739_2_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null periventricular stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10082 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null molecular transducer activity GO Molecular Function Annotations 2015 1.0 null Mas-related G protein-coupled receptor E InterPro Predicted Protein Domain Annotations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r6 part of spinal trigeminal nucleus, pars oralis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11196 Mafg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.7354 anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.49218 lambdoid septal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06331 GSE195663_7_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF331 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 68.4978 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05822 Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null septal nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.921516 TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3528 AKR1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08115 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null prostate HPA Tissue Protein Expression Profiles -1.0 -0.721457 BRCA1 JASPAR Predicted Transcription Factor Targets 1.0 null MTHFSD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1607 upper basal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35049 GTEX-XMK1-0626-SM-4B65A GTEx Tissue Sample Gene Expression Profiles 1.0 1.57044 Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE115363_2_v_0_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null INPP5F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93482 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.870645 GTEX-PLZ4-1226-SM-2I5FE GTEx Tissue Sample Gene Expression Profiles 1.0 1.18743 WT1-20215353-NEPHRON-PROGENITOR-MOUSE ChEA Transcription Factor Targets 2022 1.0 null periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.91946 GSE158197_6_v_10_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE92965_0_v_1_klf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S4UY-1426-SM-4AD6Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.36303 C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.870645 cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070829 GSE147210_2_v_5_kmt2d_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE130383_2_v_3_gps2_mouse RummaGEO Gene Perturbation Signatures 1.0 null mantle zone of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21858 PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null GATA2 ENCODE Transcription Factor Targets 1.0 null GTEX-T2IS-1526-SM-32QPR GTEx Tissue Sample Gene Expression Profiles 1.0 1.98965 GSE150895,GSE150896_0_v_1_kif15_human RummaGEO Gene Perturbation Signatures -1.0 null ATOH7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3396 GTEX-WZTO-0011-R8A-SM-4E3II GTEx Tissue Sample Gene Expression Profiles 1.0 2.66759 H3K9me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles 1.0 0.979309 HCC2185 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.957242 GSE140607_0_v_6_pioglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null hypothalamus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.893703 GSE178255_5_v_0_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCOR1-26117541-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5766 GSE87404,GSE87812_1_v_0_hoxa9_mouse RummaGEO Gene Perturbation Signatures -1.0 null SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.939608 ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.1337 ERBB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02293 H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE217115_2_v_4_alectinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null peripheral nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.454512 gata4_18812176_jejunum_tissue_lof_mouse_gpl1261_gds3486 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.587035 GTEX-P4PP-2526-SM-3P61P GTEx Tissue Sample Gene Expression Profiles 1.0 0.83954 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OLIG2-26023283-AINV15-MOUSE ChEA Transcription Factor Targets 2022 1.0 null III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24763 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35951 mantle zone of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00577 Parasympathetic ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.938 TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957186 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TV-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE242647_2_v_0_adiponectin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-OIZG-0226-SM-2TC5L GTEx Tissue Sample Gene Expression Profiles 1.0 1.38688 TCF7-22412390-EML-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Piriform-amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70456 RCOR1 ENCODE Transcription Factor Targets 1.0 null 496100405_TCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.14092 CNN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90845 ZSCAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21747 ZNF574 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.5514 PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null dorsomedial nucleus, terminal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7689 ETS1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null QGP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE195743_1_v_4_lhx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null mRNA_EED_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Piriform-amygdalar area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37553 H3K27ac_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NANOG ChEA Transcription Factor Targets 1.0 null GSE100316_7_v_1_mtor_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OHPK-2526-SM-3MJH9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.866951 GTEX-OHPL-1826-SM-2YUN8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01016 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.853525 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.58458 mantle zone of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14748 MZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32367 GSE94849_7_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 MYB ENCODE Transcription Factor Targets 1.0 null SRF JASPAR Predicted Transcription Factor Targets 1.0 null lateral part of r1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01564 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE162739_7_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.940837 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YI-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YPEL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92099 r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07292 GTEX-WYBS-1926-SM-3NM8N GTEx Tissue Sample Gene Expression Profiles 1.0 1.04497 CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QXCU-0326-SM-2TC63 GTEx Tissue Sample Gene Expression Profiles 1.0 0.824122 TDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66024 Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.08627 ITM2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1914 D341Med DepMap CRISPR Gene Dependency 1.0 2.05664 GSE226091,GSE226092_3_v_1_sall1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06995 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09487 GSE158632_2_v_0_oxyquinoline_human RummaGEO Drug Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-8021-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14893_KO_H11_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.76309 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902087 Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.9925 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE154350_1_v_0_ascl2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE123502,GSE123504_1_v_0_chd4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE220693_1_v_0_cgas_mouse RummaGEO Gene Perturbation Signatures -1.0 null duodenum HPA Tissue Gene Expression Profiles -1.0 -0.877723 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TCF7-22412390-EML-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null dorsal terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55698 SOX2 ChEA Transcription Factor Targets 1.0 null lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31287 H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56795 Anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07898 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.285316 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles 1.0 0.889971 Perturb_10740_KD_Ddx3_SRP324914 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.52178 H3K56ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE218580_1_v_4_fentanyl_mouse RummaGEO Drug Perturbation Signatures 1.0 null inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23411 GSE149903_0_v_2_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null Locus ceruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23843 POLR2AphosphoS5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE148066,GSE157787_8_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 74.6547 Skin TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CAMLG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83653 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0309 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7798 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.85184 GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7102 GTEX-S7SE-0011-R8A-SM-2XCDG GTEx Tissue Sample Gene Expression Profiles 1.0 1.1522 Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null signal transduction GO Biological Process Annotations 2015 1.0 null IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04849 GTEX-X261-0011-R11A-SM-4E3JY GTEx Tissue Sample Gene Expression Profiles 1.0 0.843134 GSTM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70107 GTEX-POMQ-0326-SM-2I5FO GTEx Tissue Sample Gene Expression Profiles 1.0 1.10174 H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE93674_1_v_0_ezh2_mouse RummaGEO Gene Perturbation Signatures -1.0 null anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.914498 GSE215351,GSE215794_1_v_0_kdm8_mouse RummaGEO Gene Perturbation Signatures 1.0 null MZ in retrosplenial cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.840284 GSE248045,GSE248046_0_v_1_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-R3RS-0726-SM-3GIJR GTEx Tissue Sample Gene Expression Profiles 1.0 1.00272 paraventricular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26355 periventricular stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46905 GB2 DepMap CRISPR Gene Dependency 1.0 3.03697 SLC25A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67744 immunodeficiency GWASdb SNP-Phenotype Associations 1.0 0.464565 VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21326 GSE135514_8_v_3_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE149903_0_v_7_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC2935 DepMap CRISPR Gene Dependency 1.0 2.10419 Artery - Coronary GTEx Tissue Gene Expression Profiles 2023 1.0 1.35411 GSE138001_0_v_3_rorb_mouse RummaGEO Gene Perturbation Signatures -1.0 null VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.68079 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null cervix uteri GTEx Tissue Gene Expression Profiles 1.0 1.17314 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.27243 GSE172295_4_v_2_sh3gl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null GSE168797_2_v_3_cannabidiol_human RummaGEO Drug Perturbation Signatures -1.0 null posteromedial visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12446 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null GPR19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25459 Retrosplenial area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05926 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_11110_KO_Tsc1_SRP303636 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.74641 496100572_HIP_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.73354 MZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07809 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE186440,GSE186443_6_v_5_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null Primary motor area, Layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10503 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3228 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21438 GSE92434_1_v_0_ebf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null r5 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.03246 CTCF ChEA Transcription Factor Targets 1.0 null skeletal muscle HPA Tissue Gene Expression Profiles -1.0 -0.877723 ZNF143 ENCODE Transcription Factor Targets 1.0 null POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NFK9-2026-SM-3LK5K GTEx Tissue Sample Gene Expression Profiles 1.0 0.934056 BMI1 ChEA Transcription Factor Targets 1.0 null GSE210667_3_v_2_rfx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75615 COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20696 GSE201882,GSE201883_3_v_5_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-RU72-2626-SM-4GIE1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.83649 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15956 POLR2A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null demyelinating disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.197766 GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles 1.0 1.71505 ZFP14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 144.273 g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36103 BT12 DepMap CRISPR Gene Dependency 1.0 2.08451 VAESBJ DepMap CRISPR Gene Dependency 1.0 6.66348 mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51886 JUND ENCODE Transcription Factor Targets 1.0 null BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64974 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.19493 GSE149903_3_v_2_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH2227 CCLE Cell Line Gene CNV Profiles 1.0 1.92827 CCDC34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52534 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.4582 Infundibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.305 GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles 1.0 1.45157 POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47213 nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.197766 reticular formation of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22376 H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.83571 GTEX-QVJO-0011-R9A-SM-2S1QH GTEx Tissue Sample Gene Expression Profiles 1.0 2.77983 Granulosa cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.865 MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.913 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.93937 Nephrogenic syndrome of inappropriate antidiuresis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 shell of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79497 UBE2F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62849 decreased urine magnesium level MGI Mouse Phenotype Associations 2023 1.0 null GSE116930,GSE116935_3_v_0_hes7_human RummaGEO Gene Perturbation Signatures -1.0 null GSE58724_3_v_0_oxymetholone_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE212330_1_v_3_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07907 GSE109285_3_v_2_glucagon_mouse RummaGEO Drug Perturbation Signatures 1.0 null RERFLCAI CCLE Cell Line Gene CNV Profiles 1.0 1.40124 molecular_function GO Molecular Function Annotations 2015 1.0 null AUP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96111 Immunoglobulin heavy-and-light chain DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.212 OSR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9415 Atoh1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.0694 GATA2-19941826-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null arcuate nucleus of medulla, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.901153 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA2, stratum lacunosum-moleculare Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17115 SOX9-25088423-EMBRYONIC GONADS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9538 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.34631 MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHLA266 DepMap CRISPR Gene Dependency 1.0 2.52154 paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05324 periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55481 Perturb_17420_Mut_Jak3_SRP168570 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 POLR2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MELHO CCLE Cell Line Gene CNV Profiles 1.0 1.7989 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.03428 GLI3T_Lipofectamine transfection_GDS4346_616_human_Panc-1 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null OLIG2-29049317-MOUSE-SPINALCORD ChEA Transcription Factor Targets 2022 1.0 null 496100382_PCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.14852 SETDB1-19884257-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null BHLHA15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2366 GSE217071_1_v_2_ythdf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-UTHO-2926-SM-3P5Z9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46151 GTEX-QDT8-0011-R2A-SM-32PKQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.72174 GSE147943_2_v_3_cited2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3 Rummagene Transcription Factor Associations 2026 1.0 null GSE237426_0_v_1_eif4a1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PANC0203 DepMap CRISPR Gene Dependency 1.0 3.34358 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.955654 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03223 GSE226770_1_v_0_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null JAR DepMap CRISPR Gene Dependency 1.0 3.738 Multiple sclerosis GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.569897 Magnocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54488 vascular disease GWASdb SNP-Disease Associations 1.0 0.084736 paraventricular nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5706 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3308-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EGR1-23403033-LIVER-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-QCQG-1226-SM-48U23 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15567 POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59332 NCIH747 DepMap CRISPR Gene Dependency 1.0 2.68396 GSE70499_4_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null FOSL1_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE184356_1_v_2_tfam_human RummaGEO Gene Perturbation Signatures -1.0 null lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.9867 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.971962 liver HPA Tissue Gene Expression Profiles -1.0 -0.877723 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.197766 USF2_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ileocecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.232039 ETS1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 part of nucleus gracilis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13174 NCIH1650 CCLE Cell Line Gene CNV Profiles -1.0 -1.64488 GATA1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37763 superficial stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14748 GSE119564_2_v_0_zfp217_mouse RummaGEO Gene Perturbation Signatures 1.0 null telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068111 MXI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null muscle GTEx Tissue Gene Expression Profiles -1.0 -1.34514 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.74705 GSE76425_0_v_12_lenalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XPVG-0626-SM-4B65B GTEx Tissue Sample Gene Expression Profiles 1.0 1.28907 SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1665 GSE111660_2_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null Ikzf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 44.4742 periventricular stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14493 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.83216 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59759 GSE118617,GSE118619_0_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Vomeronasal organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.958 CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 1.16947 ZBTB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5564 small intestine HPA Tissue Protein Expression Profiles -1.0 -0.721457 F36P DepMap CRISPR Gene Dependency 1.0 3.29947 Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.1191 GSE99187_1_v_0_gemcitabine_mouse RummaGEO Drug Perturbation Signatures -1.0 null rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.9844 membrane LOCATE Predicted Protein Localization Annotations 1.0 null Isolated growth hormone deficiency type IB DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.515 CTCF_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.9111 FAM156B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02947 MAX_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null core of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53045 Migraine DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.405 GSU DepMap CRISPR Gene Dependency 1.0 10.1305 Perturb_13165_KD_Myc_SRP057021 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.5274 H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null F5 DepMap CRISPR Gene Dependency 1.0 2.15195 GTEX-RVPV-1226-SM-2TF73 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25422 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SSA3-0426-SM-32QPI GTEx Tissue Sample Gene Expression Profiles 1.0 0.975784 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897204 GTEX-TKQ2-1326-SM-4DXT9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.936266 ZNF682 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.6125 Cell type cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 GSE248858_4_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null ZNF708 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0942 GTEX-UPIC-0226-SM-3GADO GTEx Tissue Sample Gene Expression Profiles 1.0 1.25774 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.89933 NANOG-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19102 RELB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3049 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE136238_1_v_0_ebf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE173232_2_v_3_sf3b1_human RummaGEO Gene Perturbation Signatures -1.0 null TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5KW-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased urine magnesium level IMPC Knockout Mouse Phenotypes 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of PHyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68643 GSE222758_0_v_1_clofazimine_human RummaGEO Drug Perturbation Signatures -1.0 null FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8403 GTEX-VJYA-0426-SM-3GIJK GTEx Tissue Sample Gene Expression Profiles 1.0 1.10571 GSE135244_0_v_1_trdmt1_human RummaGEO Gene Perturbation Signatures -1.0 null RBFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57801 amygdala BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.24908 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.030352 Posterolateral visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5886 GSE132948,GSE132949_2_v_3_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.856314 TCF3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null olivary pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29137 GTEX-OHPN-2826-SM-3LK67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.64822 CMK CCLE Cell Line Gene CNV Profiles -1.0 -1.53591 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null precuneus, left, superior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00588 GSE220287_2_v_1_mef2d_mouse RummaGEO Gene Perturbation Signatures -1.0 null MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5687 membrane GO Cellular Component Annotations 2015 1.0 null GTEX-XV7Q-1626-SM-4BRWC GTEx Tissue Sample Gene Expression Profiles 1.0 1.35238 Kidney Chromophobe_KICH_TCGA-KO-8403-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE149035_2_v_0_hepacam_human RummaGEO Gene Perturbation Signatures 1.0 null Cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42071 GSE142684_0_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null d36 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.594 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE101336_1_v_0_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null NCIH1355 CCLE Cell Line Gene CNV Profiles -1.0 -2.03657 abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.080931 EGR1 ChEA Transcription Factor Targets 1.0 null Reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 Arntl JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.4418 molecular layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.82656 Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.836978 ZNF449 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4859 GATA2_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE193258,GSE193259_9_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59164 Pain agnosia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.06 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4866-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41016 placenta HPA Tissue Protein Expression Profiles -1.0 -0.721457 GSE160765_2_v_1_twist1_human RummaGEO Gene Perturbation Signatures 1.0 null PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WZTO-0011-R3B-SM-3NMC6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.985748 TCF21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5342 JHH5 DepMap CRISPR Gene Dependency 1.0 2.69076 GSE217115_2_v_5_alectinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE190316,GSE190324_6_v_9_rbm4_human RummaGEO Gene Perturbation Signatures -1.0 null GSE241875_1_v_0_huwe1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ChIP_TCF3_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null ZFX_02_172 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.63227 GSE195743_3_v_2_lhx6_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null BHY CCLE Cell Line Gene CNV Profiles 1.0 1.3392 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27612 GATA2 ChEA Transcription Factor Targets 1.0 null Field CA3, stratum lacunosum-moleculare Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11561 PLA2G12A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.20742 YWHAZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4804 Cerebrooculofacioskeletal syndrome 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.73 central part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01012 plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 nd7/23 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.616 KGN cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.928 Perturb_794_KO_Tnfaip3_SRP332632 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE180277_0_v_1_bach2_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZN-0326-SM-3DB86 GTEx Tissue Sample Gene Expression Profiles 1.0 0.978282 VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.846248 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.88305 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 EFEMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50445 CTCF-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KLF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 96.4124 periventricular stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32579 GTEX-WFON-1626-SM-4LVMV GTEx Tissue Sample Gene Expression Profiles 1.0 1.53952 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null COV318 DepMap CRISPR Gene Dependency 1.0 2.13154 CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE202284,GSE202289_3_v_4_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZFAND5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60405 TUNAR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52221 496100539_HIP_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.91738 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11722 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE210101,GSE210114_2_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null GSE155972_0_v_1_setdb1_human RummaGEO Gene Perturbation Signatures 1.0 null Paraventricular hypothalamic nucleus, descending division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05905 MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.913859 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.912366 ZNF189 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0019 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.18453 POLDIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10398 Perturb_15239_KD_ERCC6L2_SRP349996 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.28043 GSE195582_2_v_1_pim1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80324 SETDB1 ChEA Transcription Factor Targets 1.0 null Twist2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.8894 outer CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.931035 Myometrial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.775 PCDHB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61382 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18688 signal transducer activity GO Molecular Function Annotations 2015 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null MYOD1_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE217115_2_v_0_alectinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE208254_3_v_1_irf8_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100364_TCx_possible Alzheimer's disease_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.42295 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06847 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13047 Elytron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.687 Brain Lower Grade Glioma_LGG_TCGA-DU-5854-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE167886_2_v_0_chd7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Malaria GWAS Catalog SNP-Phenotype Associations 2025 1.0 6.83979 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.890619 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16878 Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC1005 DepMap CRISPR Gene Dependency 1.0 2.48313 MFSD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34197 H9 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.894562 TRMT10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72682 BGC823 CCLE Cell Line Gene CNV Profiles 1.0 2.41033 DLX5_Deficiency_GDS4443_355_mouse_E10 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 liver GTEx Tissue Gene Expression Profiles -1.0 -1.41323 fusiform gyrus, left, bank of cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0725 Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 human immunodeficiency virus infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.234225 inferior occipital gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05871 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_MYOD1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SOX9 ChEA Transcription Factor Targets 1.0 null GSE152432_1_v_4_zrsr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5459-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neurodegenerative disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.197766 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87182 H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WK11-0926-SM-3NMAU GTEx Tissue Sample Gene Expression Profiles 1.0 0.998395 PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null NPY1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05518 mantle zone of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02068 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOSL1 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-A4M6-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFEB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7156 GTEX-RWS6-1326-SM-47JXB GTEx Tissue Sample Gene Expression Profiles 1.0 3.16913 MAX_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05109 GTEX-WYVS-1726-SM-3NMAY GTEx Tissue Sample Gene Expression Profiles 1.0 1.04011 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49158 ZNF213 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 71.0291 ZNF274_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE201309_5_v_0_matrine_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUPT1 DepMap CRISPR Gene Dependency 1.0 3.45975 GSE167218_1_v_0_hoxd12_mouse RummaGEO Gene Perturbation Signatures 1.0 null DSTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60181 GTEX-TSE9-2826-SM-4DXTF GTEx Tissue Sample Gene Expression Profiles 1.0 2.22671 SLC27A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2516 Nr1h3::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.818 lateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.883039 GSE148657_3_v_1_cd44_human RummaGEO Gene Perturbation Signatures 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.341 Posterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14647 Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12768 Perturb_11347_KO_Hdac3_SRP360955 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.1053 Median eminence TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.38 SKNMM DepMap CRISPR Gene Dependency 1.0 2.89416 GTEX-U3ZH-0226-SM-3DB7B GTEx Tissue Sample Gene Expression Profiles 1.0 1.08932 heart ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.418861 CCNT2 ENCODE Transcription Factor Targets 1.0 null USF1_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE178255_1_v_7_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE201882,GSE201883_3_v_4_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE168918_1_v_0_tmprss4_human RummaGEO Gene Perturbation Signatures 1.0 null TCF12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7118 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MIA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84117 GTEX-U3ZM-0126-SM-3DB8M GTEx Tissue Sample Gene Expression Profiles 1.0 1.31519 GSE137818_3_v_6_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE223008_7_v_3_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null MZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.864013 mRNA_SUZ12_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Lung adenocarcinoma_LUAD_TCGA-86-7953-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAPAN2 CCLE Cell Line Gene CNV Profiles 1.0 1.94939 allodynia MGI Mouse Phenotype Associations 2023 1.0 null GSE121246_1_v_0_stat5b_mouse RummaGEO Gene Perturbation Signatures 1.0 null Wt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 68.4926 GSE220914_1_v_0_zdhhc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4895-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE166315_2_v_0_docetaxel_mouse RummaGEO Drug Perturbation Signatures 1.0 null MZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9862 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.44493 gallbladder HPA Tissue Protein Expression Profiles -1.0 -0.721457 GSE195663_0_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1148 muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.054316 KLF5-20875108-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null viral infectious disease GWASdb SNP-Disease Associations 1.0 0.188753 GSE130081,GSE130082_0_v_10_neil2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08082 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36248 H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null GSE43041,GSE43044_0_v_1_ldb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-P4PP-0926-SM-48TBZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.02064 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ileitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.389 YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of cellular process GO Biological Process Annotations 2015 1.0 null rostral migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.877938 184B5 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.05093 muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056617 POLR2A ENCODE Transcription Factor Targets 1.0 null EP300_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF263_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.870645 GSE226770_1_v_6_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null GSE93309_5_v_3_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE223540_2_v_3_anxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null RIF1_KD_GDS4943_13_mouse_J1 ESC GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC56 CCLE Cell Line Gene CNV Profiles 1.0 1.71402 PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null GSE190235_3_v_2_foxo3_mouse RummaGEO Gene Perturbation Signatures 1.0 null NELFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18391 diagonal part of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21968 DLD-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881864 ASAH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74936 PATU8988T CCLE Cell Line Gene CNV Profiles 1.0 1.36898 ZNF263 ENCODE Transcription Factor Targets 1.0 null Anterior lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.564 GTEX-S4UY-1226-SM-4AD51 GTEx Tissue Sample Gene Expression Profiles 1.0 0.98815 mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66347 cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.105908 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38154 ZNF768 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.9055 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA1, stratum lacunosum-moleculare Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15949 Brain - Caudate (basal ganglia) GTEx Tissue Gene Expression Profiles 2023 1.0 1.54112 superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.828 Female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.07395 GTEX-NL4W-0011-R8a-SM-2I3G4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28313 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.521 temporal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.906897 CTCF-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_14900_KO_H15_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.27139 GSE182180_1_v_2_secretin_human RummaGEO Drug Perturbation Signatures -1.0 null lymph node HPA Tissue Protein Expression Profiles -1.0 -0.721457 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18626 GSE148692,GSE148695_7_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13191 heart TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.082343 KLF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.7323 GSE129389_0_v_6_tropifexor_mouse RummaGEO Drug Perturbation Signatures -1.0 null CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE166169_2_v_3_elp3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE203308_9_v_10_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GABPA_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100491_HIP_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.8982 intermediate part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01839 CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.74891 cell part LOCATE Predicted Protein Localization Annotations 1.0 null chr11_3228754_C_T_b38 GTEx eQTL 2025 1.0 1.10107 subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05784 Dorsomedial nucleus of the hypothalamus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16128 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20575 GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null Metaphyseal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.047 GSE168797_1_v_0_cannabidiol_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WL46-0011-R3A-SM-3TW8E GTEx Tissue Sample Gene Expression Profiles 1.0 0.920183 CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.861678 SRY ChEA Transcription Factor Targets 1.0 null HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MBIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1744 Lung adenocarcinoma_LUAD_TCGA-86-8056-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCOR1 ENCODE Transcription Factor Targets 1.0 null H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null rectum HPA Tissue Protein Expression Profiles -1.0 -0.721457 GSE137914_4_v_3_tet3_mouse RummaGEO Gene Perturbation Signatures -1.0 null PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70392 gut wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.705993 UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SMC3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.987741 GSE166169_1_v_3_elp3_mouse RummaGEO Gene Perturbation Signatures -1.0 null PDPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77849 RAD21_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DNAJB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85699 superficial stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78954 GSE223334_1_v_2_bcl11b_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00734 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2953_KD_Mll3_SRP029581 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 1.88113 layer 1 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02777 layer 2 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.13952 SOX2-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE247775_1_v_0_tmprss2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XUJ4-2126-SM-4BOOX GTEx Tissue Sample Gene Expression Profiles 1.0 0.871323 GSE198826,GSE198911_1_v_2_dexamethasone_mouse RummaGEO Drug Perturbation Signatures 1.0 null r5 part of the oral Sp5 subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03361 H2AL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28258 principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.91593 H3K36me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07393 H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE168807_0_v_7_dnmt3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43279 AGRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95411 medial part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2897 D502MG DepMap CRISPR Gene Dependency 1.0 2.54855 GTEX-OOBK-2626-SM-2HMKY GTEx Tissue Sample Gene Expression Profiles 1.0 1.24927 GSE210101,GSE210114_1_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null GSE113106_2_v_5_dnm2_mouse RummaGEO Gene Perturbation Signatures 1.0 null JHH6 CCLE Cell Line Gene CNV Profiles 1.0 1.71643 EGR1-23403033-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34694 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.439 skin HPA Tissue Protein Expression Profiles 1.0 1.03283 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pituitary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.87277 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0309 Migraine without aura DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.037 HES6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.483 GSE126345_7_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null Phosphatidylinositol 3-kinase complex, class II COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.561 LMO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64908 Chronic urticaria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.166 GTEX-S341-1326-SM-4AD72 GTEx Tissue Sample Gene Expression Profiles 1.0 1.67524 GSE173997_1_v_0_clic4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XUW1-0326-SM-4BOOR GTEx Tissue Sample Gene Expression Profiles 1.0 1.18144 CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.68319 451LU COSMIC Cell Line Gene Mutation Profiles 1.0 null Erg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 46.5991 NFYB-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HCFC1 ENCODE Transcription Factor Targets 1.0 null GSE171837_1_v_2_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null TCF3-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE137144_2_v_6_nlrp3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE153871_0_v_3_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null COLO-680N COSMIC Cell Line Gene Mutation Profiles 1.0 null hypertension GWASdb SNP-Disease Associations 1.0 0.783797 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.64065 GSE141328_3_v_2_rock2_mouse RummaGEO Gene Perturbation Signatures 1.0 null MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34522 496100371_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.57833 OXCT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67987 chr11_3240660_CAGGG_C_b38 GTEx eQTL 2025 1.0 1.64734 GSE202284,GSE202289_1_v_4_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null peripheral nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.587629 GTEX-SIU8-0626-SM-2XCDN GTEx Tissue Sample Gene Expression Profiles 1.0 0.918901 GSE199899_4_v_2_diethylnitrosamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Perturb_3223_KO_Nhe1_SRP366933 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.80382 plasma membrane GO Cellular Component Annotations 2015 1.0 null periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63621 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE162739_6_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.890619 disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.197766 ZNF341 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4184 GSE109530,GSE109531_2_v_0_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE140607_3_v_6_pioglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27222 GSE216540_10_v_6_fulvestrant_human RummaGEO Drug Perturbation Signatures 1.0 null layer 5 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67394 GSE76425_0_v_3_lenalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.054747 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01767 Prostate adenocarcinoma_PRAD_TCGA-EJ-5531-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE148066,GSE157787_0_v_1_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE180185_7_v_1_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE201882,GSE201883_3_v_1_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null ETS1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null GTEX-R53T-1526-SM-48FEK GTEx Tissue Sample Gene Expression Profiles 1.0 0.927052 496100369_PCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.35186 GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 0.916524 mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07292 GSE215351,GSE215794_1_v_3_kdm8_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.51828 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.864852 SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 Retrosplenial area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02547 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XM-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TPM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86611 GABPA_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20856 Perturb_4590_KO_Ezh2/Runx1_SRP066416 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.66955 MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Migrasome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.638 appendix HPA Tissue Protein Expression Profiles -1.0 -0.721457 GSE140607_5_v_6_pioglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null VAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41042 Hypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.64 posteromedial cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02313 TRAK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05318 JVE015 DepMap CRISPR Gene Dependency 1.0 5.28092 GTEX-Q2AG-0011-R2A-SM-2HMIT GTEx Tissue Sample Gene Expression Profiles 1.0 3.19352 GTEX-XLM4-0005-SM-4AT4P GTEx Tissue Sample Gene Expression Profiles 1.0 0.853625 GTEX-XYKS-1426-SM-4BRUO GTEx Tissue Sample Gene Expression Profiles 1.0 1.11723 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Anteroventral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51498 Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP53-18474530-U2OS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Ahr::Arnt JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.625 alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065684 GTEX-U3ZN-1926-SM-4DXSG GTEx Tissue Sample Gene Expression Profiles 1.0 0.897252 SREBF2 JASPAR Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA2_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null GTEX-TSE9-2626-SM-4DXV2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.67934 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36192 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4098-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE235596_0_v_1_pikfyve_mouse RummaGEO Gene Perturbation Signatures 1.0 null DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957186 Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MYOD1 ENCODE Transcription Factor Targets 1.0 null inferior temporal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.932594 H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07564 H3K4me1_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.051953 GSE166536_1_v_2_docetaxel_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE160017,GSE160022_1_v_0_trem2_mouse RummaGEO Gene Perturbation Signatures 1.0 null facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46001 Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE214931_4_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20575 Colon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Medial preoptic nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3387 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43P-01A-31R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE149903_3_v_7_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null UGCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82489 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE149903_0_v_1_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null RAB9A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69167 Lung squamous cell carcinoma_LUSC_TCGA-39-5034-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZN-0726-SM-4DXT5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46192 r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05982 parasitic helminthiasis infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.638282 HEC116 DepMap CRISPR Gene Dependency 1.0 2.53603 Primary somatosensory area, mouth, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05926 Retrosplenial area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09382 Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26023 Anterior hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08565 superficial stratum of PCPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22995 Mesothelioma_MESO_TCGA-MQ-A4KX-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC25A35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82524 Zic1::Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.1633 ChIP_REST_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null EWSR1-FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 320.095 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08326 Biceps femoris TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.589 NCIH1915 CCLE Cell Line Gene CNV Profiles 1.0 2.19285 HCC1806 CCLE Cell Line Gene CNV Profiles -1.0 -1.95596 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.958386 H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE181966_5_v_3_has2_mouse RummaGEO Gene Perturbation Signatures 1.0 null G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18139 Male reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 CA14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99036 reticular formation of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36186 GSE186440,GSE186443_3_v_5_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null PMC12818133-mmc1.pdf-10-MAFB_MAFB Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7866 496100385_TCx_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.48162 H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_15364_KO_Mef2c/Mef2d_SRP064307 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GSE192689_0_v_1_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null REST ChEA Transcription Factor Targets 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70531 Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.834412 GTEX-P4QT-1826-SM-2S1NJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.68938 Ankle joint TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.946 r1 part of intermediate nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88757 Prostate disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 Testis TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PAX6 ChEA Transcription Factor Targets 1.0 null GTEX-XYKS-2726-SM-4E3IC GTEx Tissue Sample Gene Expression Profiles 1.0 1.19392 OLIG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6963 HCC70 CCLE Cell Line Gene CNV Profiles -1.0 -1.92541 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.027506 Lung adenocarcinoma_LUAD_TCGA-91-8497-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE70499_4_v_6_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE162739_8_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1048 Colorectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 lymph node HPA Tissue Gene Expression Profiles -1.0 -0.877723 GSE84148,GSE96938_3_v_1_nrros_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE186440,GSE186443_1_v_5_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null GSE244072_10_v_9_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9091 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE178255_5_v_7_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.82079 superficial stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09293 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35951 GSE129389_0_v_5_tropifexor_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE248045,GSE248046_6_v_5_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE148066,GSE157787_9_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Midbrain trigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15875 H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE248045,GSE248046_4_v_1_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TBL1XR1 ENCODE Transcription Factor Targets 1.0 null GYPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32851 H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null PMC12021535-CPH4-15-e70011-s001.xlsx-S21-KLF2_KLF2 Rummagene Transcription Factor Associations 2026 1.0 null 496100353_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.53021 BAIAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18498 BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0291 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE186440,GSE186443_4_v_5_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.84933 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null MXI1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ventromedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21753 496100426_PCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.27242 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.09059 PRDM9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 526.843 SP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 145.095 GSE216274,GSE216292_4_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE161170,GSE161268_1_v_3_med1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE171352_2_v_3_glucagon_human RummaGEO Drug Perturbation Signatures -1.0 null Intestinal schistosomiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.292 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null GSE223334_1_v_0_bcl11b_mouse RummaGEO Gene Perturbation Signatures 1.0 null PPP1R26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30015 GSE217115_3_v_5_alectinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 91.3229 GTEX-QMRM-0726-SM-2I5G8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18754 r6 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00538 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1048 TCF7 ChEA Transcription Factor Targets 1.0 null H3K27me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE145311_0_v_2_glutathione_mouse RummaGEO Drug Perturbation Signatures -1.0 null Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null KYSE-410 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE223008_4_v_12_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE132948,GSE132949_0_v_3_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Mucosal mast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.176 lower basal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50729 GTEX-U3ZN-0926-SM-4DXTU GTEx Tissue Sample Gene Expression Profiles 1.0 1.71653 Scutellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.508 periventricular stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83051 abnormality of cardiovascular system physiology GWASdb SNP-Phenotype Associations 1.0 0.087803 outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23883 MXI1 ENCODE Transcription Factor Targets 1.0 null GSE186440,GSE186443_2_v_5_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.49334 Sympathetic ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.847 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.984812 Acute Myeloid Leukemia_LAML_TCGA-AB-2991-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060663 retrosplenial cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65786 MYB_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055826 Sublaterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1373 Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14892_KO_H11_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.70844 Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.9083 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null nor10 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.379 POLR2AphosphoS5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WWYW-0011-R8A-SM-3NB3S GTEx Tissue Sample Gene Expression Profiles 1.0 0.903105 GSE112762,GSE112767_1_v_0_dgcr8_mouse RummaGEO Gene Perturbation Signatures 1.0 null Neurohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.17 GSE135030_11_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE141328_1_v_0_rock2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2 Rummagene Transcription Factor Associations 2026 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.927634 ZNF274 ENCODE Transcription Factor Targets 1.0 null H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE178255_1_v_4_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GI1 DepMap CRISPR Gene Dependency 1.0 2.58818 DDT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03755 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.948231 Lung adenocarcinoma_LUAD_TCGA-55-7914-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Trigeminal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.65 A375SKINCJ3 DepMap CRISPR Gene Dependency 1.0 2.91322 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19893 USF1_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.84168 SUM229PE DepMap CRISPR Gene Dependency 1.0 2.6801 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.23395 H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EP300_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE184884_7_v_1_gps2_mouse RummaGEO Gene Perturbation Signatures -1.0 null OLIG3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9856 SMYD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8952 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58515 TAL1 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.956017 SETDB1-19884257-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 GSE258991_1_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null WSU-FSCCL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54176 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE217115_3_v_0_alectinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01298 NRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11476 lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12391 Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.1905 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.92027 Koelliker-Fuse nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16595 Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.6331 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059796 perimammillary part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38313 TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3253 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957186 NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19517 LU-135 COSMIC Cell Line Gene Mutation Profiles 1.0 null EGR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1 ENCODE Transcription Factor Targets 1.0 null mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Olfactory organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.819 dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.963337 terminal nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19018 GSE212628_2_v_1_mier1_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100344_HIP_probable Alzheimer's disease_TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04112 H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XOT4-0726-SM-4GIAW GTEx Tissue Sample Gene Expression Profiles 1.0 1.29521 GSE223334_3_v_0_bcl11b_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-N7MT-1926-SM-3LK5N GTEx Tissue Sample Gene Expression Profiles 1.0 0.98045 GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.83161 TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7158 GSE123372,GSE123373_1_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null heart muscle HPA Tissue Protein Expression Profiles -1.0 -0.721457 gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055797 biological regulation GO Biological Process Annotations 2015 1.0 null RBE DepMap CRISPR Gene Dependency 1.0 2.83532 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-11A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81174 ZC3H11A_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF701 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 239.75 Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 65.7124 HAND2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7468 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJYA-1226-SM-3GIJ6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.945133 gastroesophageal reflux disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.658422 UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F2 ENCODE Transcription Factor Targets 1.0 null RUNX1 ChEA Transcription Factor Targets 1.0 null shell of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08038 GSE129389_0_v_4_tropifexor_mouse RummaGEO Drug Perturbation Signatures -1.0 null Proteasome storage granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.688 GTEX-OXRK-0826-SM-2HMK7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.866057 r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55481 lateral septal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.884432 ZKSCAN5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 70.0502 GSE109530,GSE109531_2_v_3_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null intermediate stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88347 GSE66931,GSE73382_1_v_0_hira_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-X4XX-0011-R10B-SM-46MWO GTEx Tissue Sample Gene Expression Profiles 1.0 0.852679 ETS1 ENCODE Transcription Factor Targets 1.0 null GSE94849_3_v_2_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null integral component of membrane GO Cellular Component Annotations 2015 1.0 null NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.8836 signaling receptor activity GO Molecular Function Annotations 2015 1.0 null r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.35478 MYOD1_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE190235_1_v_2_foxo3_mouse RummaGEO Gene Perturbation Signatures 1.0 null TRAM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7268 Lung adenocarcinoma_LUAD_TCGA-75-6211-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 POU5F1-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ZNF816 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 73.0294 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44525 GSE159446,GSE159449_1_v_0_tunicamycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40302 NCCIT COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.832 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_CBX8_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE135514_2_v_3_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null Oviduct TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Sympathetic chain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.817 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44525 Medial preoptic nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62455 disease GWASdb SNP-Disease Associations 1.0 0.027471 Trigeminal nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.164 MV411 DepMap CRISPR Gene Dependency 1.0 3.16734 WT1-20215353-NEPHRON PROGENITOR-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE161295_0_v_5_cdk8_mouse RummaGEO Gene Perturbation Signatures -1.0 null fallopiantube_5a HPA Tissue Sample Gene Expression Profiles 1.0 0.859191 H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP53 ChEA Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7539-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R53T-0726-SM-48FCS GTEx Tissue Sample Gene Expression Profiles 1.0 0.955999 H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Connective tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LN-229 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2998-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Heart - Atrial Appendage GTEx Tissue Gene Expression Profiles 2023 1.0 3.84761 Endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MERO48A DepMap CRISPR Gene Dependency 1.0 3.23384 GTEX-VJYA-0126-SM-4KL1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.08829 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null NCIH1373 DepMap CRISPR Gene Dependency 1.0 2.67133 dorsomedial preoptic area, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78954 CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF3-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9957 GSE165071,GSE165072_1_v_0_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null C4orf46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47123 H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE76771_2_v_3_atf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE234340_9_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null COV318 CCLE Cell Line Gene CNV Profiles -1.0 -1.51688 USF2 ENCODE Transcription Factor Targets 1.0 null Male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039887 precentral gyrus, right, bank of the central sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.945754 Nucleus of the lateral lemniscus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1141 facial motor nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.869966 GTEX-TSE9-2526-SM-4DXUS GTEx Tissue Sample Gene Expression Profiles 1.0 1.61142 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.98798 GRM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79193 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.893461 PACADD161 DepMap CRISPR Gene Dependency 1.0 3.83185 GSE148066,GSE157787_11_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05764 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7081-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE125219,GSE125221_3_v_8_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-R55E-0011-R9A-SM-2TC6C GTEx Tissue Sample Gene Expression Profiles 1.0 1.51982 PTGER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70273 GSE225900_1_v_0_hsdl2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Dorsomedial nucleus of the hypothalamus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.43252 CTCF_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles 1.0 0.993439 connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052783 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3835 MCM3AP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32819 GTEX-XV7Q-2526-SM-4BRV9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45179 PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GSE213996_1_v_0_fhl3_mouse RummaGEO Gene Perturbation Signatures -1.0 null parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.909456 RUNX1-22412390-EML-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null SUM102PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.668368 PPP2R3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93935 WDR53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56138 GSE71491_0_v_1_cyclophosphamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-QMRM-0005-SM-3NB2A GTEx Tissue Sample Gene Expression Profiles 1.0 0.879836 GSE173232_4_v_3_sf3b1_human RummaGEO Gene Perturbation Signatures -1.0 null SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6017 GSE228413_4_v_3_mavs_mouse RummaGEO Gene Perturbation Signatures -1.0 null CENP-A containing nucleosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.506 superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31347 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34522 GSE234340_1_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.473869 Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96608 GSE145915_5_v_1_pcm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Circumventricular organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.142 paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55159 GSE217405_0_v_1_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.832932 ZNF732 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10379 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A ENCODE Transcription Factor Targets 1.0 null GSE161184_0_v_1_tlr7_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45446 CJM CCLE Cell Line Gene CNV Profiles 1.0 1.63703 disease by infectious agent GWASdb SNP-Disease Associations 1.0 0.11646 GTEX-V955-0426-SM-3GAEL GTEx Tissue Sample Gene Expression Profiles 1.0 0.985999 GTEX-Q2AG-0011-R3A-SM-2HMJ9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.977414 superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12616 SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.995009 H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null KLM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.46567 MGRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5081 H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lymphoma_burkitts(Daudi) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.847945 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49447 GSE129725_1_v_5_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE127970_1_v_0_ebf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Inflammatory bowel disease 10 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.714 NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 73.6298 r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01575 FAM216A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95011 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null small intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.081601 NCIH1703 CCLE Cell Line Gene CNV Profiles -1.0 -1.97743 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A821-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null RUNX2-24655370-MC3T3E1-MOUSE-BONE ChEA Transcription Factor Targets 2022 1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TCF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0005 outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21757 Lung adenocarcinoma_LUAD_TCGA-97-8175-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE159206_1_v_3_drd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null TMEM199 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68251 Entorhinal area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21484 eGFP-JUNB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_13094_KD_Gcn5_SRP057021 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 17.1278 CTCF_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.059772 GSE93309_1_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Entorhinal area, medial part, ventral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2846 Interanteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12718 GTEX-OHPL-0006-SM-3MJHB GTEx Tissue Sample Gene Expression Profiles 1.0 1.37803 SKNO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.36698 CTCF ENCODE Transcription Factor Targets 1.0 null GSE200673,GSE200691_2_v_0_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Stomach Smooth Muscle Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.46647 mRNA_ZFAND3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null GTEX-NPJ8-0011-R8a-SM-2HMLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.13478 GTEX-S341-1126-SM-4AD6T GTEx Tissue Sample Gene Expression Profiles 1.0 1.08485 NCIH526 DepMap CRISPR Gene Dependency 1.0 2.79186 ZNF432 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61925 GSE173997_3_v_0_clic4_mouse RummaGEO Gene Perturbation Signatures -1.0 null KSR2_knockout_60_GSE17923 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.04029 Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C6orf132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84766 TEAD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE145323,GSE145324_1_v_0_rfx3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-S4P3-0008-SM-3NM8R GTEx Tissue Sample Gene Expression Profiles 1.0 0.846353 GSE165682_4_v_3_ptbp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE100316_0_v_6_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.987741 vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057363 CUX1 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5550-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null IZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.894932 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38514 sensory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.705173 H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE165682_2_v_1_ptbp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PF382 DepMap CRISPR Gene Dependency 1.0 3.48643 gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04364 eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Posterolateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15991 PANC1 CCLE Cell Line Gene CNV Profiles 1.0 2.09508 CTCF_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZM-0926-SM-4DXSW GTEx Tissue Sample Gene Expression Profiles 1.0 0.913531 GTEX-XUJ4-1926-SM-4BOOV GTEx Tissue Sample Gene Expression Profiles 1.0 0.881638 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NPJ7-0011-R9a-SM-2TC5R GTEx Tissue Sample Gene Expression Profiles 1.0 0.856369 HSF1 ChEA Transcription Factor Targets 1.0 null ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsalrootganglion BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.920602 bonemarrow_6a HPA Tissue Sample Gene Expression Profiles 1.0 0.939207 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE157050,GSE157051_2_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null intermediate stratum of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48293 GSE137818_5_v_6_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01848 UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUW1-2326-SM-4BOO5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32063 GSE228413_4_v_1_mavs_mouse RummaGEO Gene Perturbation Signatures -1.0 null Thyroid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.877782 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null pdx1_22135308_duodenum_lof_mouse_gpl1261_gds4348 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.770987 Nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01383 GSE227891_5_v_0_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE127790_4_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-X261-0011-R8A-SM-4E3I5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52294 EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE212330_1_v_0_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null GTEX-OOBJ-2026-SM-3NB1R GTEx Tissue Sample Gene Expression Profiles 1.0 1.16026 TP53-18474530-U2OS-human ChEA Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles 1.0 0.892572 r6 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14545 retina BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.826581 LPCAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81917 GTEX-WZTO-0011-R10B-SM-4E3KB GTEx Tissue Sample Gene Expression Profiles 1.0 0.939703 GTEX-P4PP-2026-SM-3P61N GTEx Tissue Sample Gene Expression Profiles 1.0 2.611 GSE124097_3_v_0_trem2_mouse RummaGEO Gene Perturbation Signatures 1.0 null REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNF139 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55035 PANC0203 CCLE Cell Line Gene CNV Profiles 1.0 2.37986 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067614 GSE93309_1_v_3_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE100316_3_v_6_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null core of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63837 P30-OHK COSMIC Cell Line Gene Mutation Profiles 1.0 null CGRP receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.535 H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE224096_3_v_0_cocaine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE112860_3_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-V1-A8MU-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056454 Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.3246 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957186 Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100354_PCx_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.73518 Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TCF12_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18535 GSE203308_14_v_0_brf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null WT1 ChEA Transcription Factor Targets 1.0 null cingulate gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.699444 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE199660_1_v_0_secretin_mouse RummaGEO Drug Perturbation Signatures 1.0 null MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27222 HSF1-23293686-STHDH-STRIATAL-MOUSE ChEA Transcription Factor Targets 2022 1.0 null cortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.965335 GSE130383_1_v_3_gps2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PRRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82262 GSE171837_0_v_3_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null KIAA0319L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87175 YH13 CCLE Cell Line Gene CNV Profiles -1.0 -1.66002 MYOG ENCODE Transcription Factor Targets 1.0 null GTEX-W5X1-2626-SM-4LMI8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07855 496100492_TCx_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.39472 Prostate adenocarcinoma_PRAD_TCGA-EJ-5530-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_ASCL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CTCF_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VDAC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9268 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63621 BE2M17 DepMap CRISPR Gene Dependency 1.0 2.08854 hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.911852 Barrington's nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04172 GTEX-XGQ4-0008-SM-4AT3Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.26662 KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null PATZ1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 216.252 Hypothalamic medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01609 H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NPJ7-0011-R8a-SM-2I3G2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.25451 Retrosplenial area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00734 Dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41401 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07743 ATAD3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47611 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.943 Prostate adenocarcinoma_PRAD_TCGA-HC-7740-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055277 TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9631 Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29912 GTEX-S4P3-1326-SM-4AD6V GTEx Tissue Sample Gene Expression Profiles 1.0 0.830123 Dorsomedial nucleus of the hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84622 cerebral gray matter TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.393819 Reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1077 H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.80136 Prostate adenocarcinoma_PRAD_TCGA-J4-A6M7-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.995103 GSE153871_5_v_3_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XYKS-1626-SM-4BRUQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.20919 Uterine endometrium TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100351_FWM_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1798 Sarcoma_SARC_TCGA-DX-A23Y-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.86784 DMS454 CCLE Cell Line Gene CNV Profiles 1.0 1.4943 GSE111660_4_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null regulation of biological process GO Biological Process Annotations 2015 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51315 musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043346 cerebellar vermis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.51477 Acute Myeloid Leukemia_LAML_TCGA-AB-2911-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null gut TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.391553 H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-H9-7775-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE138938_1_v_3_foxp2_human RummaGEO Gene Perturbation Signatures 1.0 null NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.37849 basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.989783 GSE79291_1_v_2_streptozotocin_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null b220.bcell BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.60065 GTEX-R55E-0326-SM-48FD2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.94534 BMI1-19503595-MEFSC-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Hinge joint TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.942 GTEX-S7SE-2526-SM-2XCDL GTEx Tissue Sample Gene Expression Profiles 1.0 1.23803 pancreas HPA Tissue Gene Expression Profiles -1.0 -0.877723 Parasympathetic nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.731 KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881864 r7 part of cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45813 Brain Lower Grade Glioma_LGG_TCGA-TM-A84C-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE239373_0_v_1_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055825 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TSE9-3026-SM-3DB76 GTEx Tissue Sample Gene Expression Profiles 1.0 0.996409 Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH358 DepMap CRISPR Gene Dependency 1.0 3.19628 uterus GTEx Tissue Gene Expression Profiles 1.0 1.27552 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 DPEP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63158 LMSU CCLE Cell Line Gene CNV Profiles 1.0 3.2803 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null DLD1 CCLE Cell Line Gene CNV Profiles 1.0 1.49196 NFYA-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PUR1 MotifMap Predicted Transcription Factor Targets 1.0 null SPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22167 cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043754 OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25534 GSE219103,GSE219104_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE148066,GSE157787_8_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24352 PPP1R14A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04314 GSE95386_0_v_1_trim24_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE178255_1_v_0_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null multiple sclerosis DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.197766 WT1-25993318-PODOCYTE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Adenohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.582 NAP1L5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5976 JIMT1 CCLE Cell Line Gene CNV Profiles -1.0 -2.41553 GTEX-WHPG-0226-SM-3NMB9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.964951 TCF3 ENCODE Transcription Factor Targets 1.0 null ZNF281 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 216.646 GSE175683_3_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures 1.0 null REST-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null breast HPA Tissue Protein Expression Profiles -1.0 -0.721457 Dorsal premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01504 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null Internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 superficial stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.034 GTEX-TMMY-1926-SM-4DXUU GTEx Tissue Sample Gene Expression Profiles 1.0 1.44224 Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral premammillary nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34812 KMCH1 DepMap CRISPR Gene Dependency 1.0 4.77044 NCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null GTEX-T5JC-2126-SM-32PMO GTEx Tissue Sample Gene Expression Profiles 1.0 0.990834 retrohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3252 intrinsic cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.134093 CAPAN1 DepMap CRISPR Gene Dependency 1.0 2.44686 Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, upper limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29273 Communication disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.035 stratum pyramidale of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03622 PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10003 MYC ENCODE Transcription Factor Targets 1.0 null H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.4337 Lung adenocarcinoma_LUAD_TCGA-L4-A4E5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ascl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 47.2987 HMGN3 ENCODE Transcription Factor Targets 1.0 null esophagus HPA Tissue Protein Expression Profiles 1.0 1.03283 GSE192689_0_v_3_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null MOTN1 CCLE Cell Line Gene CNV Profiles -1.0 -1.39137 MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE196407_1_v_0_fluorouracil_mouse RummaGEO Drug Perturbation Signatures -1.0 null STRADB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24711 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG8-1826-SM-4LVM4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.48216 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.35574 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Urticaria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.132 KCNK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5931 GTEX-Q2AG-2926-SM-2HMJ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10025 MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 191.864 GSE146156_2_v_3_tagap_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-SE5C-0726-SM-4BRWY GTEx Tissue Sample Gene Expression Profiles 1.0 1.46035 GSE131887_1_v_4_doxycycline_mouse RummaGEO Drug Perturbation Signatures 1.0 null EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null C10 DepMap CRISPR Gene Dependency 1.0 2.50257 MXI1_02_173 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.67807 GTEX-S7SE-0011-R11A-SM-2XCDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.01931 inner SZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.882423 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5096-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EGR1 ENCODE Transcription Factor Targets 1.0 null mantle zone of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45813 H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.956352 POU5F1-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null DICER1_KO_GDS4504_586_mouse_bone marrow granulocyte-macrophage progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE190186,GSE190188_8_v_10_apoe_mouse RummaGEO Gene Perturbation Signatures 1.0 null superior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06314 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.70122 GSE150349_0_v_1_msx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GATA1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE125219,GSE125221_4_v_8_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null GSE142684_0_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null CIAO2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04757 POU5F1 ChEA Transcription Factor Targets 1.0 null Adrenal Gland GTEx Tissue Gene Expression Profiles 2023 1.0 3.28657 Peripheral ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.415 GSE126345_9_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null GATA2-19941826-K562-human ChEA Transcription Factor Binding Site Profiles 1.0 null autonomic nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.364513 GSE171837_3_v_1_bortezomib_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE171401_1_v_2_adnp_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QDVN-0626-SM-2I3FP GTEx Tissue Sample Gene Expression Profiles 1.0 0.931458 CDK18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39105 GSE93309_1_v_0_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.898614 MYOG_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.829523 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15645 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_ASCL1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE149943_2_v_3_cd8a_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZR751 DepMap CRISPR Gene Dependency 1.0 3.73945 ChIP_CTCF_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NUMBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33373 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23449 G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3067 GSE258991_5_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE125862_2_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_2021_Mut_Ikzf3_SRP308042 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Reflex, Abnormal CTD Gene-Disease Associations 1.0 1.09401 GSE89018_1_v_8_cry2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Periventricular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08136 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.287593 r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66159 MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NELFE ENCODE Transcription Factor Targets 1.0 null GTEX-X4XX-0011-R8B-SM-46MWM GTEx Tissue Sample Gene Expression Profiles 1.0 1.06201 TEAD1 JASPAR Predicted Transcription Factor Targets 1.0 null OPM2 DepMap CRISPR Gene Dependency 1.0 2.02104 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null arcuate nucleus of medulla, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.913168 Ventral premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.03784 soft tissue HPA Tissue Protein Expression Profiles 1.0 0.764697 human immunodeficiency virus infectious disease GWASdb SNP-Disease Associations 1.0 0.544946 central part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24962 dorsomedial preoptic area, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18861 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE236486_1_v_0_arnt_human RummaGEO Gene Perturbation Signatures -1.0 null 496100408_PCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.27762 PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Mouth TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE150895,GSE150896_0_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3924 GSE148066,GSE157787_11_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE213228_4_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE166315_5_v_4_docetaxel_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null arrhythmogenic right ventricular cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.757786 Spinal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.416 H3K4me3_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null layer 4 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68563 CTSL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23393 GTEX-WYBS-0926-SM-3NM94 GTEx Tissue Sample Gene Expression Profiles 1.0 0.962595 AML193 DepMap CRISPR Gene Dependency 1.0 2.1348 P2RY11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07334 GSE148066,GSE157787_8_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE142588_2_v_1_cinobufagin_human RummaGEO Drug Perturbation Signatures 1.0 null principal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23224 Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881563 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DHTKD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67471 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.79819 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27284 muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.053521 GTEX-XLM4-0726-SM-4AT64 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879934 Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE81803,GSE81912_0_v_5_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null peduncular part of dorsomedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9896 GSE234340_4_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE234340_10_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QDT8-2526-SM-48TYX GTEx Tissue Sample Gene Expression Profiles 1.0 0.860697 GATA3 ENCODE Transcription Factor Targets 1.0 null GTEX-S3XE-0626-SM-4AD6B GTEx Tissue Sample Gene Expression Profiles 1.0 0.93132 GSE151494_8_v_3_nrp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 DAZAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63255 Lung adenocarcinoma_LUAD_TCGA-86-6851-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.60458 sirolimus_mus musculus_gpl1261_gse21755 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_17031_KD_Nr3c1_SRP149816 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSE87404,GSE87812_1_v_3_hoxa9_mouse RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059549 H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CBX3 ENCODE Transcription Factor Targets 1.0 null cerebral gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.614571 POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ileum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.298524 hypoparathyroidism-deafness-renal disease syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 NR2F2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE201520_8_v_3_inhba_mouse RummaGEO Gene Perturbation Signatures -1.0 null ISL1-27105846-CHIP-SEQ-CPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null receptor activity GO Molecular Function Annotations 2015 1.0 null GSE100316_5_v_2_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE208254_4_v_5_irf8_mouse RummaGEO Gene Perturbation Signatures 1.0 null MYOD1_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 G protein-coupled receptor activity GO Molecular Function Annotations 2025 1.0 null EP300_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S1-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09868 SCCOHT1 DepMap CRISPR Gene Dependency 1.0 2.05465 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLF4 JASPAR Predicted Transcription Factor Targets 1.0 null GSE178255_2_v_6_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null KMS27 CCLE Cell Line Gene CNV Profiles 1.0 1.38065 GTEX-R53T-1026-SM-48FCO GTEx Tissue Sample Gene Expression Profiles 1.0 1.25356 Adrenocortical carcinoma_ACC_TCGA-OR-A5J2-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE198165,GSE198166_6_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null Muscular coat TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.785 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.56342 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36683 vertical nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29306 MZ in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23927 Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7935 GTEX-RWS6-1726-SM-47JXP GTEx Tissue Sample Gene Expression Profiles 1.0 1.85231 GTEX-WHSE-0011-R8A-SM-3P5Z1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.833728 Prostate adenocarcinoma_PRAD_TCGA-G9-6363-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.987741 GTEX-S4P3-0526-SM-4AD58 GTEx Tissue Sample Gene Expression Profiles 1.0 0.829429 HEP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0242 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.946128 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43003 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null PTBP1_02_07 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.54432 GSE186707_1_v_0_hdac4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GPCR, rhodopsin-like, 7TM InterPro Predicted Protein Domain Annotations 1.0 null Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23565 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.286 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.523194 GSE139987_1_v_2_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23377 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RX-A8JQ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PML_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1166 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9115 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.5595 MYC_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.73214 Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFON-1526-SM-4LVMP GTEx Tissue Sample Gene Expression Profiles 1.0 0.844815 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10666 GSE75976_3_v_6_abl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.998694 GTEX-S4P3-1126-SM-4AD52 GTEx Tissue Sample Gene Expression Profiles 1.0 0.889083 right ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.705583 GSE203308_9_v_3_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.33704 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1048 Olig2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.7805 mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.97041 MZ in posteroventral (inferior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.989672 Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null larva TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.357802 Nitrate reductase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.025 Cranial ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.644 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45585 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 locus coeruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20507 GSE93309_5_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ANAPC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78599 MATR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7278 Prostate carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 chr11_3237292_C_G_b38 GTEx eQTL 2025 1.0 2.60977 CEBPD_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.93207 GSE85302_4_v_1_kat6a_mouse RummaGEO Gene Perturbation Signatures 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42383 Pancreas GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.827703 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60964 GSE178255_3_v_7_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null testis HPA Tissue Protein Expression Profiles 1.0 1.03283 IPO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82304 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE164483_2_v_0_venetoclax_mouse RummaGEO Drug Perturbation Signatures 1.0 null inner SZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.930717 GSE100316_3_v_4_mtor_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles 1.0 1.04506 Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CMAH_KO_GDS4200_114_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.7 GTEX-RNOR-0011-R9A-SM-2TF52 GTEx Tissue Sample Gene Expression Profiles 1.0 2.0637 GTEX-XUZC-1626-SM-4BRVP GTEx Tissue Sample Gene Expression Profiles 1.0 1.05983 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04057 paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.84297 H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null GTEX-WZTO-0011-R5B-SM-3NMC5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.844106 CTCF_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE146074_10_v_3_ly6e_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.76977 planum temporale, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28175 GTEX-OIZG-0926-SM-3LK5Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.27311 ARHGEF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59209 SHF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69478 496100370_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.13171 ZNF692 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.0907 GTEX-N7MS-0011-R2a-SM-2HML6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.42296 Artery - Aorta GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.703028 GSE167956_1_v_0_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.185 HSC3 CCLE Cell Line Gene CNV Profiles 1.0 1.41596 H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ADAM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24819 H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HSF1-23293686-STHDH_STRIATAL-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null transverse gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.912402 parasitic infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.315366 SIHA COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-UTHO-2726-SM-4JBH9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08259 Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4288 Primary somatosensory area, mouth, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11761 EP300 ENCODE Transcription Factor Targets 1.0 null FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8125 GSE149903_4_v_2_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-O5YW-1826-SM-2YUN2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.897656 SUDHL6 CCLE Cell Line Gene CNV Profiles 1.0 1.48366 horizontal nucleus of the diagonal band, transitional part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09194 GTEX-P78B-2226-SM-3P5ZZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.43114 CTCF_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE92965_0_v_1_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE185944_5_v_3_pth1r_mouse RummaGEO Gene Perturbation Signatures 1.0 null TCF12 ENCODE Transcription Factor Targets 1.0 null GABPA ENCODE Transcription Factor Targets 1.0 null GTEX-XV7Q-1526-SM-4BRWB GTEx Tissue Sample Gene Expression Profiles 1.0 1.52831 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.970897 GSE189789_0_v_1_oridonin_human RummaGEO Drug Perturbation Signatures 1.0 null muscular coat TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.891798 GSE76425_0_v_7_lenalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null Anterior hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39601 GSE228413_2_v_5_mavs_mouse RummaGEO Gene Perturbation Signatures 1.0 null Agnosia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.1 SRY-25088423-EMBRYONIC-GONADS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null KELLY CCLE Cell Line Gene CNV Profiles -1.0 -1.49417 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.882306 lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.830747 MAFK_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEPSIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89934 PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null schistosomiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.803616 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071252 GTEX-WY7C-0226-SM-3NB37 GTEx Tissue Sample Gene Expression Profiles 1.0 0.882561 GSE118766_2_v_0_ifng_mouse RummaGEO Gene Perturbation Signatures 1.0 null intermediate periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88621 Rfx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.162 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27284 NCIH292 CCLE Cell Line Gene CNV Profiles 1.0 1.40613 MYOD1_myocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3301 GSE208096_1_v_0_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045374 TRIM28 ENCODE Transcription Factor Targets 1.0 null CORL279 DepMap CRISPR Gene Dependency 1.0 4.16123 Muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.11988 H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.49643 GSE217405_0_v_1_osimertinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28973 GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.971112 GTEX-PWCY-1426-SM-48TCT GTEx Tissue Sample Gene Expression Profiles 1.0 2.1117 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.60708 r3 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03361 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XN-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XGQ4-0126-SM-4AT4H GTEx Tissue Sample Gene Expression Profiles 1.0 1.12078 chr11_3209239_C_A_b38 GTEx eQTL 2025 1.0 1.32354 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0537 GSE146074_6_v_8_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8097 RNF41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7077 H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48277 GLS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90483 GTEX-T2IS-2926-SM-32QPO GTEx Tissue Sample Gene Expression Profiles 1.0 0.911163 SUM149PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.770693 CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.727926 MDAMB361 CCLE Cell Line Gene CNV Profiles -1.0 -2.71264 REST ENCODE Transcription Factor Targets 1.0 null H3K27me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXO1_KO_GSE46025_480_mouse_CD8 T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null mantle zone of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38435 GSE148193_1_v_0_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ChIP_SETDB1_19884257 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE217441,GSE217443_1_v_0_ivosidenib_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE94849_1_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null Superior colliculus, motor related, intermediate gray layer, sublayer a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02078 Sarcoma_SARC_TCGA-FX-A3NK-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE98898_4_v_1_hoxa1_human RummaGEO Gene Perturbation Signatures 1.0 null TNP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07636 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22019 GTEX-VJYA-2026-SM-4KL1K GTEx Tissue Sample Gene Expression Profiles 1.0 1.11933 GTEX-QCQG-1326-SM-48U24 GTEx Tissue Sample Gene Expression Profiles 1.0 2.25032 posterobasal nucleus, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00285 HEC6 DepMap CRISPR Gene Dependency 1.0 3.00581 IZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1042 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.49833 ChIP_NANOG_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.34334 GTEX-XV7Q-0526-SM-4BRWR GTEx Tissue Sample Gene Expression Profiles 1.0 1.49672 Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCMCRM2 DepMap CRISPR Gene Dependency 1.0 2.64344 NB10 DepMap CRISPR Gene Dependency 1.0 4.61492 A2780 DepMap CRISPR Gene Dependency 1.0 2.84179 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.13254 Perturb_10738_KD_Ddx3_SRP324914 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GSE122215,GSE122217_0_v_1_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 NFYA JASPAR Predicted Transcription Factor Targets 1.0 null forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062397 Bt TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.679 r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57847 H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE155305_3_v_0_ifitm3_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100306_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20256 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.1698 JURLMK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.37984 smooth muscle HPA Tissue Protein Expression Profiles 1.0 1.03283 CREB1 JASPAR Predicted Transcription Factor Targets 1.0 null CTCF_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24765 CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ6-0126-SM-48TC6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01533 MYT1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89743 Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28 superficial stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88966 TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4131_OE_PS2APP_SRP092532 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.46264 GTEX-T2IS-0011-R3A-SM-32QPB GTEx Tissue Sample Gene Expression Profiles 1.0 0.862848 r5 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.26413 GSKIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36269 heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.057015 GSE149903_6_v_1_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null vagina GTEx Tissue Gene Expression Profiles 1.0 0.884576 N-27 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.533 POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE155305_2_v_0_ifitm3_mouse RummaGEO Gene Perturbation Signatures 1.0 null G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10602 Perturb_3384_KO_Hobit_SRP060705 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 PPARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0714 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE168233_0_v_1_setdb1_human RummaGEO Gene Perturbation Signatures 1.0 null trans-synaptic protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.939 GSE74490_0_v_1_triptolide_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65883 H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41808 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE246053_4_v_3_hnf4a_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCOA2_KO_GDS4785_172_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE179880_7_v_5_e2f4_mouse RummaGEO Gene Perturbation Signatures 1.0 null cingulate gyrus, parietal part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.49668 GSE73561,GSE73563_0_v_1_mef2c_mouse RummaGEO Gene Perturbation Signatures 1.0 null frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.74939 mRNA_ETV3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96608 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68519 SRY-25088423-EMBRYONIC GONADS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.828281 GTEX-R3RS-0626-SM-48FE1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.60343 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126345_7_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59743 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.37289 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hypertension GWASdb SNP-Phenotype Associations 1.0 0.681114 PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF Rummagene Transcription Factor Associations 2026 1.0 null GSE179002_3_v_1_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Primary somatosensory area, upper limb, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19306 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.04249 TE1 CCLE Cell Line Gene CNV Profiles -1.0 -2.13861 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal septopreoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07325 membrane part GO Cellular Component Annotations 2015 1.0 null ventral part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14748 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null enteric nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.750405 mantle zone of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.26228 ChIP_SOX2_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943646 SNU1079 DepMap CRISPR Gene Dependency 1.0 4.6133 superficial stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11196 CHD2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00421 alphaT3-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.913 Perturb_3340_KO_Cns4_SRP310440 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.18719 COPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15546 Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055448 CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -1.767 Perturb_13164_KD_Gcn5_SRP057021 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 WM88 DepMap CRISPR Gene Dependency 1.0 3.04089 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA ChEA Transcription Factor Targets 2022 1.0 null SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.880818 GATA1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6754 MYOG_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null paraventricular nucleus, peduncular or principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46842 OCUM1 DepMap CRISPR Gene Dependency 1.0 4.23016 Odorant GPCRs(Mus musculus) WikiPathways Pathways 2014 1.0 null GTEX-S4P3-0226-SM-3K2BD GTEx Tissue Sample Gene Expression Profiles 1.0 0.953175 Enteric nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.87 GSE118794_2_v_1_zmynd8_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PIP5KL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00767 GSE138001_2_v_4_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null USF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null D283MED CCLE Cell Line Gene CNV Profiles -1.0 -1.73795 CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ventromedial hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61648 496100499_PCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.32077 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A6JB-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE210580_0_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null JAK1_knockdown_160_GSE37012 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.52229 EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2374 L428 DepMap CRISPR Gene Dependency 1.0 2.2757 HENMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39744 SK-MES-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_9766_KO_Shp2_SRP285005 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.85059 cuneus, left, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.980636 GSE173232_1_v_0_sf3b1_human RummaGEO Gene Perturbation Signatures 1.0 null RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fallopian tube HPA Tissue Protein Expression Profiles 1.0 1.03283 GSE149903_4_v_7_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null Posterior pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31743 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44445 GSE126345_0_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42259 pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06582 GSE214823,GSE214824_0_v_2_crtc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Skin - Sun Exposed (Lower leg) GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.765366 GSE76425_0_v_5_lenalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE235234_2_v_3_corticosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE136627_2_v_1_hdac4_mouse RummaGEO Gene Perturbation Signatures 1.0 null intestinal schistosomiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.2717 PLPPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79447 ASCL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.2979 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10602 Acute Myeloid Leukemia_LAML_TCGA-AB-2886-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142684_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null Hip joint TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.753 Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FEZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.2302 Uterus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24352 Smooth muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 dorsal part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13067 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 0.927915 Prdm15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.4609 NFIC JASPAR Predicted Transcription Factor Targets 1.0 null OLIG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0998 BHLHE23 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5216 TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2128 SOX2-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.69805 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.987741 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25383 GSE157049,GSE157051_6_v_1_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null superficial stratum of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14545 MXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5677 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.23622 FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19517 PCDHB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17975 SAMHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9993 Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25062 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE114258_3_v_0_foxk1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QVJO-0011-R8A-SM-447C7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3099 HUH-6-CLONE5 COSMIC Cell Line Gene Mutation Profiles 1.0 null periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65977 Lung adenocarcinoma_LUAD_TCGA-86-8075-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE119564_2_v_3_zfp217_mouse RummaGEO Gene Perturbation Signatures 1.0 null REST_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMIZ1 ENCODE Transcription Factor Targets 1.0 null GSE148066,GSE157787_11_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE96641_5_v_0_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CHD2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64315 Male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.9261 PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Male reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 GTEX-RU72-2926-SM-2TF66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01314 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SMG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30763 GTEX-P4QS-1826-SM-2S1NI GTEx Tissue Sample Gene Expression Profiles 1.0 1.21444 urinary bladder HPA Tissue Protein Expression Profiles -1.0 -0.721457 JVM3 DepMap CRISPR Gene Dependency 1.0 5.25022 GSE179880_10_v_3_e2f4_mouse RummaGEO Gene Perturbation Signatures 1.0 null FBXW5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.152 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01848 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11722 TAGLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74889 Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterolateral cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26716 GSE244072_10_v_3_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE178255_2_v_0_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Primary somatosensory area, barrel field, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13859 superior parietal lobule, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30225 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.89538 H3K36me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.0688 GSE135030_8_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null CUX1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G protein-coupled receptor activity GO Molecular Function Annotations 2023 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE100316_5_v_6_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null Female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.24629 GSE242096,GSE242098_1_v_0_med1_mouse RummaGEO Gene Perturbation Signatures 1.0 null mRNA_NANOG_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 49.347 supramarginal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04671 GTEX-RVPV-0011-R11A-SM-2TF6F GTEx Tissue Sample Gene Expression Profiles 1.0 0.923792 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.90818 BMI1-19503595-MEFC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE178255_3_v_6_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE208254_3_v_2_irf8_mouse RummaGEO Gene Perturbation Signatures -1.0 null EB2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IQ-01A-31R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Oral mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-XUW1-0226-SM-4BOOS GTEx Tissue Sample Gene Expression Profiles 1.0 1.20631 Testis GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.703028 liver HPA Tissue Protein Expression Profiles -1.0 -0.721457 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE178255_1_v_6_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Mixed sleep apnea DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.426 chr11_3262756_G_A_b38 GTEx eQTL 2025 1.0 3.98909 Sensory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.657 CEBPD ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.02284 SJSA1 CCLE Cell Line Gene CNV Profiles 1.0 1.65344 DLAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04089 Anterior olfactory nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14331 TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35869 GTEX-PX3G-2526-SM-48TZV GTEx Tissue Sample Gene Expression Profiles 1.0 1.10115 Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.36074 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46284 GTEX-W5WG-1326-SM-4LMI9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.919004 RT11284 CCLE Cell Line Gene CNV Profiles -1.0 -1.41498 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anosognosia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.091 intermediate pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30692 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.047933 superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57998 GSE166315_1_v_0_docetaxel_mouse RummaGEO Drug Perturbation Signatures 1.0 null periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24306 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.17412 spleen HPA Tissue Protein Expression Profiles -1.0 -0.721457 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.05477 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.8637 GSE202603_0_v_2_bhlhe40_mouse RummaGEO Gene Perturbation Signatures -1.0 null Microtubule organizing center attachment site COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.014 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gut wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.054 NAMALWA DepMap CRISPR Gene Dependency 1.0 2.65584 STAT5A ENCODE Transcription Factor Targets 1.0 null Perturb_10160_KD_TNFAIP8_SRP271403 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.0865 Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.3284 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6617 GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11192 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.14781 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20575 GTEX-XOTO-0011-R9A-SM-4GICI GTEx Tissue Sample Gene Expression Profiles 1.0 1.3353 NANOG-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70263 Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52915 GSE149901_3_v_0_anlotinib_human RummaGEO Drug Perturbation Signatures -1.0 null TBP ENCODE Transcription Factor Targets 1.0 null spinal cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064649 GTEX-RU72-0011-R2A-SM-2TF6O GTEx Tissue Sample Gene Expression Profiles 1.0 2.04197 GSE178255_5_v_6_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null CKAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45398 HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.839511 Internal female genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 shell of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22019 H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3456-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.586 GSE147210_3_v_4_kmt2d_mouse RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01701 FLI1 ChEA Transcription Factor Targets 1.0 null rostral subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39932 ETV5::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.7968 CTCF_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_10739_KD_Ddx3_SRP324914 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.87752 GSE140607_1_v_6_pioglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 0.836653 STK11_knockout_278_GSE34866 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.41591 TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.6857 layer 6 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3569 basolateral amygdaloid nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06942 THAP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.5541 21205295-TableS1 GeneSigDB Published Gene Signatures 1.0 null r3 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61716 cerebral white matter TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.362273 ZNF257 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 95.1555 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.07928 MCF7 CCLE Cell Line Gene CNV Profiles -1.0 -1.53278 GTEX-PLZ4-2726-SM-3P61A GTEx Tissue Sample Gene Expression Profiles 1.0 1.7854 GTEX-T5JW-1226-SM-3GACY GTEx Tissue Sample Gene Expression Profiles 1.0 1.14771 intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058742 GSE183413_0_v_2_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null Mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-UJHI-1326-SM-4IHJO GTEx Tissue Sample Gene Expression Profiles 1.0 1.0156 layer 6b of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34814 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.33411 ANKRD27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80227 fusiform gyrus, left, bank of the its Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.87733 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.51669 GSE211177,GSE211178_8_v_3_ets1_mouse RummaGEO Gene Perturbation Signatures -1.0 null central nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.197766 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98657 Ventromedial hypothalamic nucleus, dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24342 SOX9-25088423-EMBRYONIC-GONADS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 stratum oriens of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.907051 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT5A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE234340_12_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18904 GTEX-S3XE-1326-SM-4AD4H GTEx Tissue Sample Gene Expression Profiles 1.0 0.886865 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.781429 Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral septal nucleus, intermedio-ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66553 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null stratum oriens of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26965 Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 3 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18329 GSE223540_1_v_3_anxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CAMA1 DepMap CRISPR Gene Dependency 1.0 7.84824 GSE210101,GSE210114_8_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null artery disease GWASdb SNP-Disease Associations 1.0 0.117958 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5334-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.099 methylphenidate_mus musculus_gpl11180_gse33619 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE154253_1_v_0_tnfaip8_human RummaGEO Gene Perturbation Signatures -1.0 null Sin3 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.664 Prostate adenocarcinoma_PRAD_TCGA-EJ-5518-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67887 precentral gyrus, left, superior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07127 GSE246184,GSE246195_0_v_1_sin3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-T6MO-1426-SM-4DM73 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07172 GSE168797_1_v_5_cannabidiol_human RummaGEO Drug Perturbation Signatures 1.0 null superficial dorsofrontal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22995 GTEX-SUCS-0226-SM-32PLQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.846627 r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51761 GTEX-WFJO-0226-SM-3GIKW GTEx Tissue Sample Gene Expression Profiles 1.0 0.921729 IRX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34185 GSE211177,GSE211178_9_v_11_ets1_mouse RummaGEO Gene Perturbation Signatures 1.0 null cysticercus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.28009 USF2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PP-1826-SM-2S1NT GTEx Tissue Sample Gene Expression Profiles 1.0 0.96729 CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.956017 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.67088 HCC1187 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.861178 TPD52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01025 superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.53461 ZNF384_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2014_KO_Xbp1_SRP061216 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 planum polare, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.973749 H3K9me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.876397 GTEX-PW2O-0126-SM-48TC8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.48489 ATP2A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5378 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5944-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF638 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55007 Schistosomiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.187 EP300_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE93309_5_v_0_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE112860_5_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null HBA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60802 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.45032 POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P78B-0526-SM-2I5F7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24217 ENTREP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44102 Muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.32944 POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE185944_0_v_1_pth1r_mouse RummaGEO Gene Perturbation Signatures -1.0 null LGALS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90024 r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.345 GSE122378_0_v_1_carmil3_mouse RummaGEO Gene Perturbation Signatures 1.0 null