association	dataset	threshold value	standardized value
CHLA266	DepMap CRISPR Gene Dependency	1.0	2.46307
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961883
hsa-miR-4520a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Fatty Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
CJM	CCLE Cell Line Gene CNV Profiles	1.0	1.4433
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34457
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
THAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54927
GATA2_01_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.52496
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.534
19139136-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Medial geniculate complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05329
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.935933
TM31	DepMap CRISPR Gene Dependency	1.0	3.08641
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12073
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74131
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59835
HS944T	CCLE Cell Line Gene Expression Profiles	1.0	1.79561
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.832495
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SG-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1686
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872536
external cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11528
SCC15	CCLE Cell Line Gene Expression Profiles	1.0	1.64089
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Preeclampsia_Placenta_GSE4707	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52097
Thyroid Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Usher syndrome type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.755
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46813
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KASUMI1	DepMap CRISPR Gene Dependency	1.0	2.07484
CUX1	ChEA Transcription Factor Targets	1.0	null
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05455
m2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05878
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1214
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21324
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.16712
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34968
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H376	DepMap CRISPR Gene Dependency	1.0	2.36356
mantle zone of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0016
SIN3A	ENCODE Transcription Factor Targets	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052053
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.6105
ERCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60649
periventricular stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0412
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23845
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5951
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.09432
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30535
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF404	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37638
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.50594
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11988
SP1	ENCODE Transcription Factor Targets	1.0	null
ID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91639
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.5949
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873456
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9119
Lung adenocarcinoma_LUAD_TCGA-78-7150-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07254
Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81614
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53459
BCL11B_KO_GDS3178_296_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853224
Brain Lower Grade Glioma_LGG_TCGA-HT-8109-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
causes	GeneRIF Biological Term Annotations	1.0	null
K562	DepMap CRISPR Gene Dependency	1.0	2.21215
Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
process	GeneRIF Biological Term Annotations	1.0	null
PDIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78105
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09645
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Presenile Dementia	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A731-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A1KU-01A-32R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23357
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39821
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02813
BHY	CCLE Cell Line Gene Expression Profiles	1.0	1.43683
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24618
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WX-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A2	ChEA Transcription Factor Targets	1.0	null
YRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33436
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37482
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.43515
hsa-miR-3138	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3532
Subparafascicular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69315
SCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5748
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00477
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20041
HT144	CCLE Cell Line Gene Expression Profiles	1.0	2.16963
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
breast	GTEx Tissue Gene Expression Profiles	1.0	1.0781
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3891
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5152-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5781
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14243
JHESOAD1	DepMap CRISPR Gene Dependency	1.0	3.81878
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15845
SP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27229
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.7223
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15685
COV434	DepMap CRISPR Gene Dependency	1.0	2.7446
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86143
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.81209
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2336
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UT-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
ARFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94123
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55712
esophagus	GTEx Tissue Gene Expression Profiles	1.0	1.01448
DEL	DepMap CRISPR Gene Dependency	1.0	3.27966
DMS-273	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9245
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19701
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84198
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16033
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.43706
hsa-miR-448	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.26089
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4060771-170289.f1.pdf-201-MLL_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01047
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0726
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20X-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
647V	DepMap CRISPR Gene Dependency	1.0	2.39451
Tumor Initiation	DisGeNET Gene-Phenotype Associations	1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79872
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27981
signal transduction	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839376
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22303
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	3.44876
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05123
Rectum adenocarcinoma_READ_TCGA-AF-5654-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13903
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8417-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73075
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19453
DGCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51886
Albinism	DisGeNET Gene-Disease Associations	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25827
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32443
Islet Cell Tumor	DisGeNET Gene-Disease Associations	1.0	null
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64899
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2354
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NUDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68763
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21415
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15739
Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FI-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CK-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.07696
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44474
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KYSE410	DepMap CRISPR Gene Dependency	1.0	2.43962
PTRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43592
layer 3 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20737
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05555
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64185
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01472
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03235
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.147839
mesomere 2 (preisthmus or caudal midbrain)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20315
mantle zone of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19265
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1317
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06052
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2564
NCI-H1703	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0937
Encephalomyelitis	DisGeNET Gene-Disease Associations	1.0	null
16273092-TableS1c	GeneSigDB Published Gene Signatures	1.0	null
Spinothalamic tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
mantle zone of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51389
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17334
membrane part	GO Cellular Component Annotations 2015	1.0	null
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
UBFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79006
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32364
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7342
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0318
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33833
sublayer 6b of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43619
HS294T	CCLE Cell Line Gene Expression Profiles	1.0	1.84969
anteroventral part of alar thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01194
mantle zone of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41313
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23357
GSE48812_3_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8634-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.35681
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996869
FADS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09092
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.839218
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83518
HS729	CCLE Cell Line Gene CNV Profiles	1.0	1.33739
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
HMGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.943
PANC0213	CCLE Cell Line Gene Expression Profiles	1.0	1.4939
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96584
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25255
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF6_KO_GDS2359_126_mouse_skin E17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21967
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29466
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03942
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PDF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46588
Rosacea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
Bipolar Disorder	DisGeNET Gene-Disease Associations	1.0	null
ZNF229	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4337
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EPHA4_knockout_226_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.984407
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
EKVX	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LB771HNC	DepMap CRISPR Gene Dependency	1.0	2.59858
SNUC2A	CCLE Cell Line Gene Expression Profiles	1.0	1.57973
Merkel Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75271
A2058	CCLE Cell Line Gene Expression Profiles	1.0	2.40873
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05498
Arthritis	DisGeNET Gene-Disease Associations	1.0	null
ventrolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12556
KCNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91847
Laryngeal Cleft	DisGeNET Gene-Disease Associations	1.0	null
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24936
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
MYDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01638
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2086
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09584
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91319
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19886
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.36998
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.64517
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1616
Prostate adenocarcinoma_PRAD_TCGA-HC-7818-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3126-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65753
HUH7	DepMap CRISPR Gene Dependency	1.0	2.0532
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.65317
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41767
KASUMI2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63378
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.5381
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01759
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
Hyperparathyroidism	DisGeNET Gene-Disease Associations	1.0	null
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80671
ZNF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54565
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0576
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256902
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97257
EIF4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66148
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHRAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3421
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1423
MEL285	DepMap CRISPR Gene Dependency	1.0	2.286
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059912
SCC25	CCLE Cell Line Gene Expression Profiles	1.0	1.92631
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11961
Brain Lower Grade Glioma_LGG_TCGA-CS-4938-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RASSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02015
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79632
EP300	ENCODE Transcription Factor Targets	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907915
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13859
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.54051
ATPAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60504
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33008
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2915
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
Inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1237
hsa-miR-4428	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15487
Androgen insensitivity syndrome_Fibroblast_GSE3871	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.74054
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.66765
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92604
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDIT4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59285
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7385
KMS20	DepMap CRISPR Gene Dependency	1.0	2.6326
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7173
PECAPJ49	CCLE Cell Line Gene Expression Profiles	1.0	1.44731
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079445
GSE195568_1_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5369-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8169
Primary somatosensory area, trunk, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14367
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.4926
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.586
Neural crest-derived stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2982
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIMMDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79672
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
HCE4	DepMap CRISPR Gene Dependency	1.0	3.98601
Graves Disease	DisGeNET Gene-Disease Associations	1.0	null
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D341Med	DepMap CRISPR Gene Dependency	1.0	2.16755
grhl3_16949565_skin_lof_mouse_gpl1261_gds2629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.168445
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54374
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50338
PMC4060771-170289.f1.pdf-200-MLL_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.529047
RCCFG2	DepMap CRISPR Gene Dependency	1.0	4.0782
SUPM2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03052
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65115
TCCSUP	DepMap CRISPR Gene Dependency	1.0	2.4665
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.871849
RNF144A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61713
IKBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96488
Gross Obesity	DisGeNET Gene-Disease Associations	1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-472-ZNF575_ZNF575	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CD-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
RNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95653
SNU398	DepMap CRISPR Gene Dependency	1.0	3.64142
HNRNPL_02_96	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.867
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43565
Mammary-basal cell	Tabula Sapiens Gene-Cell Associations	1.0	3.02254
FOXA1	ENCODE Transcription Factor Targets	1.0	null
CTAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61345
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871298
NR2F2	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4329	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2834-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	153.405
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057565
hsa-miR-17	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC8191339-mmc1.xlsx-Table_S3_DE_genes-LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845983
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961883
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
Primary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23343
RYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83938
isthmic liminal part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24186
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280717
Diarrhea	DisGeNET Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A622-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161846,GSE161849_1_v_5_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130396_7_v_6_braf_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.935
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11828
CRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17029
HSC3	CCLE Cell Line Gene Expression Profiles	1.0	1.75824
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.66063
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCA1_Knock-in_GDS1756_232_mouse_Cerebellum tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961883
Hyperactive Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
CUL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72991
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6682
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74066
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01724
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49678
mantle zone of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12556
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13009
Rheumatism	DisGeNET Gene-Disease Associations	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2416
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0
LRP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07486
G protein-coupled receptor activity	GO Molecular Function Annotations 2025	1.0	null
Primary ciliary dyskinesia 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.867
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.58159
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84918
Metallochaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
FAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12717
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03888
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2804
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25427
CREB3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8039
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA5_KO_GSE47425_386_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.16277
Toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
preisthmic midbrain tectum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06047
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00558
KYSE70	CCLE Cell Line Gene CNV Profiles	1.0	1.47632
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32558
NHBE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
Nasopharyngeal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-106b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931409
Acrodyostosis	DisGeNET Gene-Disease Associations	1.0	null
RBM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78905
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	3.13065
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97274
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3148
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18359
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A633-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.2165
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01109
GALK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31622
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1589
MITD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84647
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884358
MTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5489
HASPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68982
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.95432
Lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_14362_KD_SORBS2_SRP112756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.0712
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.16988
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9094
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01598
IRAK4_Deficiency_GDS2641_653_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14549
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.2956
Odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85261
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16538
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parkinson Disease	DisGeNET Gene-Disease Associations	1.0	null
TBX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00308
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GB-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09595
NCI-H1437	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32198
ZFP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07033
intermediate tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0016
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7785
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02536
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41607
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.680656
EPCAM_OE_GDS4887_342_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SARS-CoV MA15_Day2-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79398
GLDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74597
USF1	ENCODE Transcription Factor Targets	1.0	null
CCNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0647
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Azurophil granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.3794
Congenital disorder of glycosylation type I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35494
KYM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61521
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.15035
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7067-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.969834
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92064
oaw28	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
TE1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.36952
Brain Lower Grade Glioma_LGG_TCGA-RY-A845-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-AB2X-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57458
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HO-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18501
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2467
SFMBT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6442
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14921
UMUC13	DepMap CRISPR Gene Dependency	1.0	2.48243
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11444
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01835
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66702
NCIH520	DepMap CRISPR Gene Dependency	1.0	2.14256
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950218
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOX-1_OE_GDS4262_434_human_HAECT - aortic endothelial cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99993
molecular_function	GO Molecular Function Annotations 2015	1.0	null
REXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.087
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.195
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94564
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cone-Rod Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KSR2_knockout_60_GSE17923	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.37605
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08966
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66306
NCI-H2227	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TC205	DepMap CRISPR Gene Dependency	1.0	3.36619
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66093
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04909
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81614
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45312
Malaria	DisGeNET Gene-Disease Associations	1.0	null
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55611
Dermatofibrosarcoma	DisGeNET Gene-Disease Associations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185519_1_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70914
Mandibular incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
Portal Hypertensive Gastropathy	DisGeNET Gene-Disease Associations	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.68817
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20234
TMEM237	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17734
A-Netherlands-602-2009(H1N1)_3Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.25976
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75084
DENND1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43056
LC1SQSF	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54668
Hunger	DisGeNET Gene-Phenotype Associations	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18332
Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46746
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00477
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32558
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960665
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934809
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GCLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54541
NCIH1092	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63812
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02033
CORL105	CCLE Cell Line Gene Expression Profiles	1.0	1.39521
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02589
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00558
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14504
normal	GeneRIF Biological Term Annotations	1.0	null
Thyroid Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Adrenal Cushing'S Syndrome	DisGeNET Gene-Disease Associations	1.0	null
SNU626	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7148
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE195568_2_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91821
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
GSS	CCLE Cell Line Gene CNV Profiles	1.0	1.82713
Ventral posterolateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54571
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873456
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Sarcoma_SARC_TCGA-LI-A9QH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Invertebrate mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
VCAP	CCLE Cell Line Gene Expression Profiles	1.0	1.4012
Hyperglycemia	DisGeNET Gene-Disease Associations	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Conventional (Clear Cell) Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55935
ZNF506	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4353
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
SOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09541
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28943
Lung adenocarcinoma_LUAD_TCGA-44-2668-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.41742
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.566134
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57897
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91657
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.98412
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90697
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10051
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I2-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07171
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1765
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.913532
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9253
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09541
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24036
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57416
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5937
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.535
SNU1040	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42399
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19473
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53504
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89928
ZSCAN16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15186
MOLM13	DepMap CRISPR Gene Dependency	1.0	2.72542
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53822
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SubthalamicNucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.954177
MET_knockout_251_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.53332
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1173
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COQ7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96846
Sarcoma_SARC_TCGA-IF-A4AK-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20969
Prostate adenocarcinoma_PRAD_TCGA-EJ-5497-01A-02R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929437
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96245
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.043
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39934
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214576
PMC3526356-supp_jem.20121387_JEM_20121387_sm.pdf-27-MEIS1_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.974
Ocular Albinism	DisGeNET Gene-Disease Associations	1.0	null
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5506
Endothelial Dysfunction	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-148a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75907
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8451
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 6 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23302
Primary somatosensory area, lower limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37521
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16668
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76036
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.547
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23357
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5744
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34923
SARS-CoV MA15_Day1_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.39086
KYAE1	DepMap CRISPR Gene Dependency	1.0	2.89975
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50872
chr11_18129798_C_T_b38	GTEx eQTL 2025	1.0	12.1644
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02665
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9774
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92604
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0016
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3591
Primary Differentiated Carcinoma Of Thyroid Gland	DisGeNET Gene-Disease Associations	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40105
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
NCIH747	DepMap CRISPR Gene Dependency	1.0	2.97736
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79081
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.707
RB1_KD_GSE50532_624_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
496100600_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13707
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE192362_1_v_0_erastin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF217	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66657
HOXD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25644
Urticaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Depression	DisGeNET Gene-Disease Associations	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60741
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.87872
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26959
RBM34_02_121	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.20645
KDM6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73208
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41607
HS695T	CCLE Cell Line Gene Expression Profiles	1.0	1.48054
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Orbital area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0318
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47226
SRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69066
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98861
Rectum adenocarcinoma_READ_TCGA-AG-4022-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73004
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51458
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76027
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43076
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74021
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03942
Polymicrogyria, Bilateral Frontoparietal	DisGeNET Gene-Disease Associations	1.0	null
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83059
Childhood Leukemia	DisGeNET Gene-Disease Associations	1.0	null
OCIAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42986
LN464	CCLE Cell Line Gene Expression Profiles	1.0	1.70741
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MBOAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72352
Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11444
NR4A2-19515692-MN9D-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventral tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41875
ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5158
COASY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11307
Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74988
PMC7880379-aging-13-202285-s003.xlsx-DElncRNA_target-FEZF1_FEZF1	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZD-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04909
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15626
A101D	CCLE Cell Line Gene Expression Profiles	1.0	2.65496
ZFHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53867
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9099
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82309
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51687
Prostate adenocarcinoma_PRAD_TCGA-VN-A88K-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2895
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.3732
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
FLO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14499
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.948527
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80658
Primary somatosensory area, lower limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07225
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86121
membrane	GO Cellular Component Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypocalciuric Hypercalcemia, Acquired	DisGeNET Gene-Disease Associations	1.0	null
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26208
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80268
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874309
Satellite glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29R-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UTP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.012
PLIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57754
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60652
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4395-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43944
KKU100	DepMap CRISPR Gene Dependency	1.0	3.43367
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98306
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19986
ZNF391	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29373
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0029
A-Netherlands-602-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.9458
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21967
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7635
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	2.13766
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59895
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JEG-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Well Differentiated Pancreatic Endocrine Tumor	DisGeNET Gene-Disease Associations	1.0	null
GSE143790_0_v_1_bcl9_human	RummaGEO Gene Perturbation Signatures	1.0	null
G protein-coupled receptor activity	GO Molecular Function Annotations 2023	1.0	null
NCIH292	CCLE Cell Line Gene CNV Profiles	1.0	1.51249
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99516
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30951
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1668
Lung squamous cell carcinoma_LUSC_TCGA-66-2765-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JIMT1	DepMap CRISPR Gene Dependency	1.0	2.37946
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.637611
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961883
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-20a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14367
hsa-miR-4255	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8187
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42291
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05207
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50727
A204	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178532_1_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mixed Anxiety And Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GIGYF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09578
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01219
Contracture	DisGeNET Gene-Disease Associations	1.0	null
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
Skin Endocrine Disorder	DisGeNET Gene-Disease Associations	1.0	null
EIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44772
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84324
YY1	ENCODE Transcription Factor Targets	1.0	null
STX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01859
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4375
Thalamus, sensory-motor cortex related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30889
Right Ventricular Hypertrophy	DisGeNET Gene-Disease Associations	1.0	null
H357	DepMap CRISPR Gene Dependency	1.0	3.09178
periventricular stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24618
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53459
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43537
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19583
GSE226355,GSE226357_3_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2BC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51152
CAL54	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61024
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07904
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09608
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JT-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reticular formation of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67705
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061953
THRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83834
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947754
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56124
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
A253	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22628
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92604
SIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48475
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59837
BHY	CCLE Cell Line Gene CNV Profiles	1.0	1.44681
TXLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67228
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Hereditary Hemochromatosis	DisGeNET Gene-Disease Associations	1.0	null
HAE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19791
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50872
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.877
cellular_component	GO Cellular Component Annotations 2015	1.0	null
SKMEL24	CCLE Cell Line Gene Expression Profiles	1.0	3.40697
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7068-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29449
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05071
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-148b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
FIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22744
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1189
FAM221A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7878
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20505
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82866
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39762
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47105
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05878
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.1004
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08607
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2982
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6484-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12083
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.85904
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62739
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25274
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17461
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38294
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41553
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52058
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13009
AAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26333
Granular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.547
Midbrain raphe nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20531
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.979287
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8342-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Conn Adenoma	DisGeNET Gene-Disease Associations	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19848
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57965
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45532
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08401
PEO4	DepMap CRISPR Gene Dependency	1.0	4.37198
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196117_1_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.3902
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3722
Congestive Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.900909
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
TP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37498
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954555
Giant Cell Fibroblastoma	DisGeNET Gene-Disease Associations	1.0	null
NCIH1869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39521
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.34915
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86137
TSPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25941
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01995
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44497
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78645
TSPAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06693
CD83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7158
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52813
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
CCNI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58838
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02384
496100413_FWM_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33966
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.73098
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06586
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37158
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.547
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00272
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3326
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923343
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
SW626	DepMap CRISPR Gene Dependency	1.0	3.55058
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8635
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73681
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25967
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03938
hsa-miR-519d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.943075
intermediate stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76009
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37033
layer 5 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10177
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8167
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74006
CADO-ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11452
lmx1b_18351676_hind_limb_bud_lof_mouse_gpl1261_gds3320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.040724
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67654
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05242
PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.477
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16986
PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
Heartburn	DisGeNET Gene-Phenotype Associations	1.0	null
MKN28	DepMap CRISPR Gene Dependency	1.0	2.41423
CRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12061
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.647756
FAM83H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58091
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27156
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
KMBC2	CCLE Cell Line Gene Expression Profiles	-1.0	-3.93455
interstitial nucleus of the zona limitans	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76009
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35674
Degenerative Polyarthritis	DisGeNET Gene-Disease Associations	1.0	null
CADM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79059
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19682
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17962
Ebolavirus(ZEBOV)_5day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.66241
Bullous keratopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
Acth-Independent Macronodular Adrenal Hyperplasia	DisGeNET Gene-Disease Associations	1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84001
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50617
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-4526	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30889
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08582
Genitourinary Cancer	DisGeNET Gene-Disease Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052133
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65324
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.879004
BCPAP	CCLE Cell Line Gene Expression Profiles	1.0	1.55029
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.671
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78559
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67705
hsa-miR-3660	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
KP2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.18799
BCL11B_KO_GSE9330_4_mouse_brain (striatum)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lens epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
Ventral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50754
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10115
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34667
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20499
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06586
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14179
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56569
H2BW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51563
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33462
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92852
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0876
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16473
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.913731
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Coronary Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.69713
GRIPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53713
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A8YN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874309
Microtubule organizing center attachment site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.494
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1859
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21967
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.78521
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73075
EMC-BAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25334
CJM	CCLE Cell Line Gene Expression Profiles	1.0	1.6812
Corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1755	DepMap CRISPR Gene Dependency	1.0	2.11588
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58781
CTCF	ENCODE Transcription Factor Targets	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.2695
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05939
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-01A-21R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.773589
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.477
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1988
Obesity	DisGeNET Gene-Disease Associations	1.0	null
496100663_TCx_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.59046
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98087
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08582
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Enzyme Inhibition Disorder	DisGeNET Gene-Phenotype Associations	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.820248
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24398
hsa-miR-152	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
VPS37C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33419
CLDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61987
superficial stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13903
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31646
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85462
liminal part of alar isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51721
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	2.12627
IFNLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61181
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35177
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29916
GATA1	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884108
NCI-H1836	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13162
vitamin c_mus musculus_gpl6246_gse19377	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02973
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
ZNF440	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33234
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02049
SLC9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23935
Lung squamous cell carcinoma_LUSC_TCGA-66-2753-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.944005
SK-N-AS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
HEY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03352
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39874
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45039
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56918
ACSBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99536
liminal alar domain of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12556
Neuralgia	DisGeNET Gene-Phenotype Associations	1.0	null
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33206
layer 6a of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77312
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09696
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08775
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.95724
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17615
Bilateral Cataracts (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
GSE234767,GSE234769_0_v_4_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8423
Aortic Valve Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04144
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17379
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6192
REXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01927
Cystic Fibrosis	DisGeNET Gene-Disease Associations	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5607
Nucleolar ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.121
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7509
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.547
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40013
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06213
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34901
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuromyelitis Optica	DisGeNET Gene-Disease Associations	1.0	null
Congenital disorder of glycosylation Ip	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.008
SMPDL3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8931
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67255
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
HS766T	DepMap CRISPR Gene Dependency	1.0	2.04
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34284
Mental Depression	DisGeNET Gene-Disease Associations	1.0	null
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03898
WSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11822
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86137
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3393
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83934
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Rectum adenocarcinoma_READ_TCGA-CL-4957-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03488
PMC10061014-Table7.XLSX-C_vs_L-Table_S7a_Predicted_upstream_regulators_of_genes_showing_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A-CA-04-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.72571
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5665
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5025
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
Tumor Angiogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19151
Triple Negative Breast Neoplasms	DisGeNET Gene-Disease Associations	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3626
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9448
Get-1_Deficiency_GDS2629_161_mouse_embryonic skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6961-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87012
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63879
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JI-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6506-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11782
ROCK_INHIBITION_GDS3944_462_mouse_Forebrain astrocytes - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0916
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07904
MYBL2	ENCODE Transcription Factor Targets	1.0	null
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33715
Idiopathic Hypogonadotropic Hypogonadism	DisGeNET Gene-Disease Associations	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
ventral posterolateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91116
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21996
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
Triple-Negative Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34923
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75907
Orbital area, lateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15685
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76786
MYOZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59066
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30682
ADAM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1056
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88033
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03008
IFIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31526
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05939
GRHL3_01_336	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.56444
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.54091
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5951
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28828
hsa-miR-20b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
SP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07507
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055252
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
WM793	CCLE Cell Line Gene Expression Profiles	1.0	2.05203
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38509
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055665
CYBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64775
Depressed Mood	DisGeNET Gene-Phenotype Associations	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054333
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897357
Uterine Carcinosarcoma_UCS_TCGA-ND-A4W6-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	2.49596
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20108
intermediate stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67705
biological regulation	GO Biological Process Annotations 2015	1.0	null
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49918
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11961
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29916
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36847
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.547
Septicemia	DisGeNET Gene-Disease Associations	1.0	null
EPCAM_OE_GDS4887_343_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36973
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.20101
TE441T	CCLE Cell Line Gene Expression Profiles	1.0	1.60765
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.235
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34094
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53459
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12318
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80699
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.83581
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14243
Differentiated Thyroid Gland Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
GCT	CCLE Cell Line Gene Expression Profiles	1.0	2.17214
A-CA-04-2009(H1N1)_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64777
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51586
Corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7212-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961883
Usher Syndrome	DisGeNET Gene-Disease Associations	1.0	null
NDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54462
Von Willebrand Disease	DisGeNET Gene-Disease Associations	1.0	null
Withdrawal Symptoms	DisGeNET Gene-Phenotype Associations	1.0	null
PK45H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70012
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0318
CYFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45773
hsa-miR-889	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871298
GSE145990_1_v_5_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052044
hsa-miR-4649-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71749
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02559
MAFF	ENCODE Transcription Factor Targets	1.0	null
NCI-H524	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.84225
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17924
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08082
REST_01_338	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.73488
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5966-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7185
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5671
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27349
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53788
FOXM1_01_77	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.05536
Alcohol Abuse	DisGeNET Gene-Disease Associations	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97844
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05715
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74066
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31102
chr11_18127105_C_G_b38	GTEx eQTL 2025	1.0	1.84288
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11828
Primary motor area, Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02404
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983716
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lumpy Skin Disease	DisGeNET Gene-Disease Associations	1.0	null
SOX5	JASPAR Predicted Transcription Factor Targets	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
CL-40	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CUEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17697
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4424
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35487
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2975
RFX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77621
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6235-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01567
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EIF4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65988
ENHO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81647
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02712
Rectum adenocarcinoma_READ_TCGA-DC-6157-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT1197	DepMap CRISPR Gene Dependency	1.0	2.6999
MDAMB453	CCLE Cell Line Gene CNV Profiles	1.0	2.25783
vitamin c_mus musculus_gpl6246_gse19378	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
KASUMI1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62174
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08582
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8768
Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
HELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53669
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01917
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87242
Prostate adenocarcinoma_PRAD_TCGA-VN-A88Q-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21083
MAP2K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3113
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0348
LAMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52748
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.17915
EMTOKA	DepMap CRISPR Gene Dependency	1.0	2.08581
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	2.19668
SW1353	CCLE Cell Line Gene Expression Profiles	1.0	1.37524
Mediodorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05555
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3698
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3823
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927274
DNASE1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70781
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10115
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
MXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45704
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51066
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79905
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0623
MDAMB453	DepMap CRISPR Gene Dependency	1.0	3.56626
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42889
SKMEL19	DepMap CRISPR Gene Dependency	1.0	2.62967
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
ZFP69B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34106
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.663
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872536
LN443	CCLE Cell Line Gene CNV Profiles	1.0	1.32864
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53284
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
TNKS_INHIBITION_GDS5029_280_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33669
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
Lung squamous cell carcinoma_LUSC_TCGA-22-5485-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34542
GSE130396_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9685
Lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.047
NFIB-24661679-E16.5 LUNG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HOXB4	ChEA Transcription Factor Targets	1.0	null
SARS-CoV MA15_Day1-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.72224
CGRP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
Thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09302
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07338
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6517
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91458
EW22	DepMap CRISPR Gene Dependency	1.0	3.60594
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46874
NFIB	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
Agnosia	DisGeNET Gene-Disease Associations	1.0	null
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991762
SKMEL2	CCLE Cell Line Gene Expression Profiles	1.0	1.52397
KOPN-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44756
RFX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76958
COX6B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92905
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WSUNHL	DepMap CRISPR Gene Dependency	1.0	2.10441
Idiopathic Pulmonary Arterial Hypertension	DisGeNET Gene-Disease Associations	1.0	null
DCTPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79213
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00477
MOB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89679
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08401
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929437
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59194
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.05383
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38879
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.8473
Prostate adenocarcinoma_PRAD_TCGA-G9-6342-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20543
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64978
EVSAT	CCLE Cell Line Gene CNV Profiles	1.0	1.43078
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00313
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.1287
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954555
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19791
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2512
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839376
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22533
furan	CTD Gene-Chemical Interactions	1.0	null
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.3283
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5329-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72294
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85925
Taste Sweet	DisGeNET Gene-Phenotype Associations	1.0	null
superficial stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1107
Lung adenocarcinoma_LUAD_TCGA-50-6595-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60581
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03888
receptor activity	GO Molecular Function Annotations 2015	1.0	null
A-CA-04-2009(H1N1)MA_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.87169
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19745
ZSCAN26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10153
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FASTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2174
CCNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63023
Multiple Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72539
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94262
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Essential Hypertension	DisGeNET Gene-Disease Associations	1.0	null
A-Vietnam-1203-2004(H5N1)_2day-TNFRSF1BKO_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.0222
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5378
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Dementia	DisGeNET Gene-Disease Associations	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Osteoporosis	DisGeNET Gene-Disease Associations	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE145990_1_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1474
PATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990042
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11361
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.07291
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74263
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05654
lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13235
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70121
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Irritable Bowel Syndrome	DisGeNET Gene-Disease Associations	1.0	null
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884108
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02589
Usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
Uveal Melanoma	DisGeNET Gene-Disease Associations	1.0	null
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02539
ESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8107
probucol_mus musculus_gpl9525_gds3618	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3113
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
voltage-gated sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRCA1_DEPLETION_GDS3791_38_human_Hela	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Corneal endothelial dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKBKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47456
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9684
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.859535
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.477
Kaposi Sarcoma	DisGeNET Gene-Disease Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03808
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Usher syndrome type 3A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.107
Chronic Pain	DisGeNET Gene-Phenotype Associations	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0711
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
MUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63333
MTREC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
Asthma	DisGeNET Gene-Disease Associations	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5813
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13431
Brain Lower Grade Glioma_LGG_TCGA-HT-7681-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subcuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14367
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15669
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46803
sublayer 6a of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04275
Corneal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
CBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55192
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65677
MFE280	DepMap CRISPR Gene Dependency	1.0	2.79098
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55287
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.21691
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52646
H2AC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12369
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13946
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74066
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42602
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7104
CC2D1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61403
Hemorrhage	DisGeNET Gene-Disease Associations	1.0	null
Calprotectin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.0
HO1U1	DepMap CRISPR Gene Dependency	1.0	2.24202
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	6.56141
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839376
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.0959
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.30938
Mas-related G protein-coupled receptor family	InterPro Predicted Protein Domain Annotations	1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79072
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.863699
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951739
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29553
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Y-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76663
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960665
Nephrogenic Diabetes Insipidus	DisGeNET Gene-Disease Associations	1.0	null
BICDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71548
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883109
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326067
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZJ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2512
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-93	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HS751T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76302
disturbance	GeneRIF Biological Term Annotations	1.0	null
Huntington Disease	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
KYSE220	DepMap CRISPR Gene Dependency	1.0	2.61644
HDQP1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64158
17676974-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Perturb_12186_KD_TP53_SRP065500	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.67522
TRIM35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32561
DES_KO_GDS4804_171_mouse_young skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10673
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48002
DNAJC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55534
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10495
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12878
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04018
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31646
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23769
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83655
Chronic Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
Meningeal Melanoma	DisGeNET Gene-Disease Associations	1.0	null
RAF1_overexpression_220_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.77697
Perturb_4298_KD_BCL9_SRP242206	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.23711
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
SW780	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37358
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PL-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43922
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47947
ventrolateral part of isA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51721
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.4204
SNU216	DepMap CRISPR Gene Dependency	1.0	2.53747
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77008
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077199
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59369
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18735
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.70791
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Decompression Sickness	DisGeNET Gene-Disease Associations	1.0	null
C7orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61877
ethinyl estradiol_oryzias latipes_gpl16266_gse44859	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-106a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052132
MRPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92579
ILF2_02_88	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.66838
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9967
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A181-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 5 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09645
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.854198
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8555
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFPAC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59361
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11427
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pulmonary alveolar proteinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.8351
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03808
hsa-miR-4772-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CHCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90448
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79695
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61999
OCILY19	DepMap CRISPR Gene Dependency	1.0	2.05352
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79208
Cataract	DisGeNET Gene-Disease Associations	1.0	null
overexpression	GeneRIF Biological Term Annotations	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.35377
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08401
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0097
a24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55711
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09645
hsa-miR-4421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	2.32323
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.64139
COLO678	DepMap CRISPR Gene Dependency	1.0	2.40409
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41506
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81111
FBXO42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52156
Papillary Thyroid Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.4106
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02033
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95233
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.68817
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1479
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	3.8235
MIEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89397
TYKNU	DepMap CRISPR Gene Dependency	1.0	2.24879
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50727
Major Affective Disorder	DisGeNET Gene-Disease Associations	1.0	null
KBTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94541
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.438
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30682
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49947
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-0.825831
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7849