association dataset threshold value standardized value SLC30A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43313 UOK101 CCLE Cell Line Gene Expression Profiles -1.0 -1.6527 NCI-H345 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943239 Perturb_17510_KD_Klf4_SRP338421 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.93457 adult retina HPM Cell Type and Tissue Protein Expression Profiles 1.0 1.14787 COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.98294 Perturb_4568_KO_Prmt1_SRP178236 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.08921 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_2376_KD_Cdk8_SRP292215 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.34821 UBB_KO_GDS3906_494_mouse_Testis - 21 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SLC45A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89689 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.88805 Neuromuscular junction disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.205 APPBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13722 SCAF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93853 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.928004 NCI-H596 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_4683_KO_Mll2/Suz12_SRP189864 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.70541 IM95 CCLE Cell Line Gene Expression Profiles 1.0 1.47019 NCI-H522 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H526 COSMIC Cell Line Gene Mutation Profiles 1.0 null endometrial carcinoma GWASdb SNP-Disease Associations 1.0 0.675077 GSE139348,GSE139349_1_v_0_dicer1_mouse RummaGEO Gene Perturbation Signatures -1.0 null LYSMD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07034 Perturb_15674_KD_Hnrnpu_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.15693 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5956 GSE157050,GSE157051_2_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC12486367-Supplementary_Data2.pdf-60-HES4_HES4 Rummagene Transcription Factor Associations 2026 1.0 null RAB3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58543 Perturb_4713_KO_Hnrnpu_SRP331236 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.76734 Werner syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.071 GSE224969,GSE224971_0_v_7_chtop_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE141328_3_v_2_rock2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_14721_KO_Bma1_SRP351647 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.62597 Perturb_17325_KO_Dis3l2_SRP322105 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.37896 GSE221327_8_v_0_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96792 GSE149870_0_v_1_pfn1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 51.3751 GSE114992,GSE114993_1_v_2_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_18554_KD_miR466c_SRP319883 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.6073 DZIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83222 Perturb_5158_KD_Zic3_SRP046299 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.52522 PIEZO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36159 inner CP in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07127 RGS14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97119 Fundus dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.014 anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.936904 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51045 SW780 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H250 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_13251_KO_Dux_SRP098643 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.61348 GSE221327_10_v_2_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null SHFL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60002 inner CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21112 abnormality of head or neck GWASdb SNP-Phenotype Associations 1.0 0.096543 GSE223008_5_v_1_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE146074_0_v_7_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null stomach GTEx Tissue Gene Expression Profiles 1.0 0.8401 Perturb_5014_OE_Prdm15_SRP064415 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.42647 oral cleft GWASdb SNP-Phenotype Associations 1.0 0.654545 Perturb_16084_KO_Nfya_SRP270915 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.46198 GSE199606_3_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Stomach TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 JEKO-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null White coat effect (clinic systolic blood pressure minus ambulatory systolic blood pressure) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.552288 liver HPA Tissue Gene Expression Profiles 1.0 0.900573 COLO-824 COSMIC Cell Line Gene Mutation Profiles 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_211_KD_AU021063_SRP324142 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.57917 GSE258991_5_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null ACSS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84781 GSE81193_0_v_4_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_9525_Mut_Thra_SRP334033 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 ARHGDIA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99349 glioblastoma multiforme GWASdb SNP-Disease Associations 1.0 0.675077 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57103 NOS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69046 GSE101336_1_v_0_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null CDK8_knockdown_163_GSE38061 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -0.574351 Atf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.3267 Perturb_11054_KO_Mettl3_SRP363782 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.17444 SNU349 CCLE Cell Line Gene Expression Profiles 1.0 2.65495 MZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.904328 Perturb_14565_KO_Got2_SRP348541 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.39329 SHROOM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36348 Perturb_8417_KO_Srsf1_SRP252896 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.47061 RCOR1 ENCODE Transcription Factor Targets 1.0 null Perturb_2021_Mut_Ikzf3_SRP308042 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 AMPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55921 GSE141328_1_v_0_rock2_mouse RummaGEO Gene Perturbation Signatures 1.0 null neoplasm GWASdb SNP-Phenotype Associations 1.0 0.179911 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902767 Perturb_13328_KD_Mnt_SRP149831 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.60594 BRCA1-C complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.887 lymphoma GWASdb SNP-Phenotype Associations 1.0 0.578475 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9978 SW1990 COSMIC Cell Line Gene Mutation Profiles 1.0 null COL8A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47628 GSE140441_2_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null NUDT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2198 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null neoplasm by anatomical site GWASdb SNP-Phenotype Associations 1.0 0.186628 Perturb_4163_KO_Aki2_SRP325507 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.3227 UIMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63409 Tonsil TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SKNMC CCLE Cell Line Gene Expression Profiles 1.0 2.13764 GGT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20646 NR4A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07529 MICALL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59955 sirolimus_homo sapiens_gpl2895_gse16944 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_13386_OE_p73_SRP069085 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.47112 MAGED4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00234 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null TOE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45118 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27829 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04354 USP45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59588 Perturb_11114_KO_Gps2_SRP140448 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.97514 KYSE-150 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null KYSE-220 COSMIC Cell Line Gene Mutation Profiles 1.0 null SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 schizophrenia GWASdb SNP-Disease Associations 1.0 1.36645 THEM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88385 GSE173232_1_v_0_sf3b1_human RummaGEO Gene Perturbation Signatures 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR Rummagene Transcription Factor Associations 2026 1.0 null HLA-C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97213 GSE145639_1_v_6_adar_human RummaGEO Gene Perturbation Signatures -1.0 null chr2_233823671_A_G_b38 GTEx eQTL 2025 1.0 2.83843 GSE169697,GSE169725_1_v_4_prrx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8454 Kinetochore microtubule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.564 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.971999 Perturb_4940_KO_Cbfa2t2_SRP061948 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 13.4555 NFRKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44868 outer CP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.62359 NR3C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4289 DNLZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94159 CANT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66341 NCI-H1915 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_3379_KO_Pgd_SRP309436 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.4223 EMC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59131 abnormal renal morphology GWASdb SNP-Phenotype Associations 1.0 0.271584 GATA2 ENCODE Transcription Factor Targets 1.0 null GSE228430_1_v_3_fabp5_human RummaGEO Gene Perturbation Signatures -1.0 null A704 CCLE Cell Line Gene Expression Profiles 1.0 1.35831 inherited metabolic disorder GWASdb SNP-Disease Associations 1.0 2.04328 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1596 Npas4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.8335 Perturb_10755_KO_Foxo1_SRP265620 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.47736 GSE148252_5_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE223893_4_v_9_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null HOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.15 GSE109530,GSE109531_1_v_0_hdac3_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6875 Perturb_212_KD_AU021063_SRP324142 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.44177 UACA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15976 GSE180200,GSE180201_12_v_9_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE133683_3_v_0_doxorubicin_mouse RummaGEO Drug Perturbation Signatures -1.0 null PL18 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE173810_0_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ORMDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43218 GATA1_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNAPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52218 PEAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0507 GSE264010_0_v_1_parp1_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_13134_KO_Pnpt1_SRP134850 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.42376 abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.145941 abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.507801 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.5904 CORO1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75024 STRA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8907 GSE138019_3_v_6_nudt12_mouse RummaGEO Gene Perturbation Signatures -1.0 null ACETAMINOPHEN GLUCURONIDE DGIdb Drug Targets 2026 1.0 9.624 GSE252988_0_v_1_lefamulin_human RummaGEO Drug Perturbation Signatures 1.0 null PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18752 ATXN7L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91451 outer CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09782 Paraplegia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.068 KIF4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27838 LYL1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MEK_INHIBITION_GDS5029_279_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE186483_1_v_0_lrrk2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF781 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87941 RHOQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70372 Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 65.539 SKP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44159 TLCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83439 abnormality of the uterus GWASdb SNP-Phenotype Associations 1.0 0.331537 GSE145249_1_v_3_ppm1g_human RummaGEO Gene Perturbation Signatures -1.0 null TPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25222 TRIM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03299 SMAD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74283 GSE237040_6_v_1_notch3_mouse RummaGEO Gene Perturbation Signatures 1.0 null H4C15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66766 PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_5542_KO|KD_Fh1|Foxa2_ERP138019 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.12527 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89043 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10264 GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18578 Perturb_11108_KO_Cpt2/Ppara_SRP303636 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.66924 RMND5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71812 GSE174751_0_v_1_postn_mouse RummaGEO Gene Perturbation Signatures -1.0 null LU-99A COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_4725_KO_Irx3_ERP116672 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2993 GSE89767_2_v_5_cebpa_mouse RummaGEO Gene Perturbation Signatures -1.0 null KAT6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94019 RT4 CCLE Cell Line Gene Expression Profiles 1.0 1.43176 IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null BCL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77914 thyroid GTEx Tissue Gene Expression Profiles 1.0 1.12033 abnormality of the astrocytes GWASdb SNP-Phenotype Associations 1.0 0.578475 HDAC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1341 Perturb_13572_KD_Setdb1_SRP059699 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.55189 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943239 GSE169205_3_v_2_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE89018_6_v_14_cry2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NKIRAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84298 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.888537 TGBC11TKB CCLE Cell Line Gene Expression Profiles 1.0 1.57857 Perturb_4779_KD_Trim24/Trp53_ERP016337 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.19804 SW756 COSMIC Cell Line Gene Mutation Profiles 1.0 null esophagus HPA Tissue Protein Expression Profiles 1.0 0.994474 GSE74251_0_v_3_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null COPS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16649 GSE220520_5_v_2_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903849 Perturb_14484_KO_Ubc9_SRP202561 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.54567 Perturb_5825_KO_Pax5_SRP185455 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -13.7985 SOX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0573 Congenital myasthenic syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.294 JDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18501 Mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.85154 GSE207914_5_v_6_nudt7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.842 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.944405 liver HPA Tissue Protein Expression Profiles -1.0 -0.936627 Perturb_13264_KO_chr7_SRP162484 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.50554 CLPSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61877 GSE81193_3_v_5_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_13072_KO_Cry2_SRP091906 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.67052 FARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87493 HS939-T COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE102598_1_v_2_nmda_mouse RummaGEO Drug Perturbation Signatures 1.0 null uterine neoplasm GWASdb SNP-Phenotype Associations 1.0 0.377222 JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.26097 GSE139948_3_v_6_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null thyroid gland HPA Tissue Gene Expression Profiles 1.0 0.858557 Perturb_3998_KD_RIOK3_SRP116196 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 MAP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92043 H3K9me3_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9326 GPHA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12573 GSE92364_1_v_5_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null Serotonin receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.052 PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63 Rummagene Transcription Factor Associations 2026 1.0 null CRIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53797 GSE81193_3_v_2_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE142210_3_v_1_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null GSE164135,GSE164137_0_v_1_fbxw7_mouse RummaGEO Gene Perturbation Signatures 1.0 null TMEM248 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23288 Perturb_8390_KO_Ssu72_SRP167695 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 18.8239 neoplasm of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.257619 GSE207302,GSE207303_0_v_2_tp53bp2_human RummaGEO Gene Perturbation Signatures 1.0 null RD CCLE Cell Line Gene Expression Profiles -1.0 -2.12986 PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX Rummagene Transcription Factor Associations 2026 1.0 null GSE169155_3_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Waardenburg syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.336 OVK-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null C11orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12955 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR Rummagene Transcription Factor Associations 2026 1.0 null Perturb_15226_OE_hIGFBP5_SRP337748 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.139235 GSE152246_0_v_1_dihydrotestosterone_human RummaGEO Drug Perturbation Signatures -1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.971999 INTS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0479 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848188 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.74502 GSE223008_5_v_2_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE239373_0_v_1_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null MYADM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19073 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.08053 MONO-MAC-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_14917_KD_Mof_SRP060636 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.90884 GSE250534_4_v_1_cabergoline_mouse RummaGEO Drug Perturbation Signatures 1.0 null depressive disorder, major GAD Gene-Disease Associations 1.0 null DRAM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63368 Perturb_12137_OE_Wdr11_SRP113332 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.79897 cancer GWASdb SNP-Disease Associations 1.0 0.155351 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15699 Perturb_10999_KO_Mcam_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.64334 Gallbladder disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.979 inner CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.54624 abnormality of the face GWASdb SNP-Phenotype Associations 1.0 0.116091 496100324_FWM_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.98714 FANCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58305 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04354 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null KALS1 CCLE Cell Line Gene Expression Profiles -1.0 -1.65071 GSE76771_2_v_3_atf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_18399_KO_Pik3cg_SRP078862 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.38416 KDM4E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51274 HS940-T COSMIC Cell Line Gene Mutation Profiles 1.0 null MSLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63673 Perturb_17683_KO_Parp1/Parp2_SRP311978 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.46544 urinary tract neoplasm GWASdb SNP-Phenotype Associations 1.0 0.292668 H3K9me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96792 UDSCC2 COSMIC Cell Line Gene Mutation Profiles 1.0 null SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06595 GSE110178_5_v_0_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures -1.0 null C8orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77473 CDR2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43382 Perturb_4941_KO_Prdm14_SRP061948 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.78762 tcf3_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.49144 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903849 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87244 Perturb_11018_KO_Prkab1_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.89229 GSE139239_2_v_6_ddr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BLTP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89614 TRIB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92384 A431 COSMIC Cell Line Gene Mutation Profiles 1.0 null endogenous depression GWASdb SNP-Disease Associations 1.0 0.750866 spleen HPA Tissue Protein Expression Profiles -1.0 -0.936627 SAP30L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91505 CORO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73135 LYL1 ChEA Transcription Factor Targets 1.0 null GSE157960_0_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null PFDN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03715 PIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52367 PPARG ChEA Transcription Factor Targets 1.0 null KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_6902_KD_Hdac5_SRP257918 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.83859 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6832 SRRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68092 PSN1 CCLE Cell Line Gene Expression Profiles 1.0 1.75447 Perturb_2953_KD_Mll3_SRP029581 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 DENND11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91305 PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE66724_DE-Genes_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.58836 TAL1_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRL_Deficiency_GDS1693_239_mouse_Photoreceptors cells of retinas at 4 weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Bilirubin levels GWAS Catalog SNP-Phenotype Associations 1.0 1.1262 496100653_PCx_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02201 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.77157 496100413_FWM_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.28144 Perturb_9529_KO_Clock_SRP252642 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.90581 stomach HPA Tissue Protein Expression Profiles 1.0 0.994474 Perturb_13275_KO_Zbtb24_SRP198761 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.54854 Perturb_16359_OE_Ppargc1a_SRP278337 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.11789 Perturb_12589_KO_Eed_SRP379883 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.64884 Perturb_852_KO_Igfbp7_SRP081229 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.70676 Perturb_11505_KO_Brg1_SRP271459 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.27111 TMX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70805 NCIH716 CCLE Cell Line Gene Expression Profiles -1.0 -1.69182 GSE247764_4_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE203308_7_v_0_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE74251_2_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_12038_KO_Trps1_SRP201986 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.70262 Perturb_9566_KO_Setd_SRP266340 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.61856 SP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09363 Perturb_15761_KO_Zfp36l1_SRP285762 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.88128 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.855571 GSE146072_0_v_1_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null A1207 CCLE Cell Line Gene Expression Profiles -1.0 -2.32461 KAT2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1271_KO_Adar_SRP132963 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.79334 Mafb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0902 Perturb_12569_KD_Sufu_SRP194252 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 nervous tissue neoplasm GWASdb SNP-Phenotype Associations 1.0 0.292668 breast carcinoma GWASdb SNP-Phenotype Associations 1.0 0.578475 FAM86B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20864 GSE186483_2_v_0_lrrk2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE71674,GSE71676_0_v_2_cbfa2t2_mouse RummaGEO Gene Perturbation Signatures 1.0 null HOXC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81565 RCOR1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC26A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05019 XPO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06451 GSE122067_3_v_1_mtch2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE148647_1_v_2_scgb1a1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GPR19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25459 PLBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6722 Perturb_3403_KO_Cbfb_SRP214434 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.0359 organelle LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_1382_KO_Sdc1_SRP286584 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.55328 NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8609 MAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78632 Skin TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCI-H1417 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100360_FWM_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.51042 SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943239 PANK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36284 Inhibitory control GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.630103 GSE236511_1_v_0_ngfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null LOVO COSMIC Cell Line Gene Mutation Profiles 1.0 null TEKTIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02369 SLITRK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68817 SCN5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42733 GSE129370_0_v_1_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE166004_5_v_4_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null COPE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87667 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.81859 GSE193993_5_v_2_sstr2_human RummaGEO Gene Perturbation Signatures -1.0 null EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9548 urinary system disease GWASdb SNP-Disease Associations 1.0 0.32814 TE1 CCLE Cell Line Gene Expression Profiles 1.0 1.55042 Perturb_17262_OE_Foxj2_SRP368260 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.8732 BEX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21174 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.13938 GSE92364_0_v_5_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null 639-V COSMIC Cell Line Gene Mutation Profiles 1.0 null Uterine endometrium TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Perturb_10233_KO_RN7SK_SRP201495 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.38229 QGP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.98294 GPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80735 Perturb_4810_KO_Atp2b4_ERP004375 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.21364 ENSG00000170846 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69918 GSE133213_9_v_15_znrf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Nfe2l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.3196 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5468 Perturb_15673_KD_Hnrnpk_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.53984 PITPNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06417 GSE147210_3_v_5_kmt2d_mouse RummaGEO Gene Perturbation Signatures 1.0 null nephrolithiasis GWASdb SNP-Disease Associations 1.0 0.793562 Perturb_15672_KD_Hnrnpc_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.57133 GSE124920_1_v_2_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15823 GSE213632_1_v_5_acod1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SAS cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.686 HS 695T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.33053 GSE226285_3_v_0_nr0b1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE138019_1_v_5_nudt12_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE100528_1_v_0_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null AGO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77238 PCI-30 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_3401_KO_Tet2_SRP267372 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.30435 496100363_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.05301 Serum bilirubin levels in metabolic syndrome GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.739794 DU4475 CCLE Cell Line Gene Expression Profiles 1.0 2.40872 Perturb_17281_KO_Gja1_SRP247546 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.26803 Perturb_6209_KO_Zcchc8_SRP187429 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.79789 JHOS4 CCLE Cell Line Gene Expression Profiles -1.0 -1.59358 GSE147210_2_v_5_kmt2d_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_11270_KO_Bmal1_SRP337469 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.21492 Perturb_2000_KO_Arid2_SRP344792 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.89934 USP44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92254 GTF2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2033 Perturb_4569_KO_Prmt1_SRP178236 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.31032 Perturb_9414_KO_Mettl14_SRP136010 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.1439 JL1 CCLE Cell Line Gene Expression Profiles 1.0 1.68714 Perturb_6953_KD_Rbm20_ERP122940 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.11564 GSE166169_1_v_3_elp3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE193999,GSE194000_3_v_2_atf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE147664_0_v_1_arid1b_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE67266_2_v_4_etoposide_mouse RummaGEO Drug Perturbation Signatures -1.0 null IL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08707 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04354 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.888417 Depressive Disorder, Major dbGAP Gene-Trait Associations 1.0 0.118912 non-small cell lung carcinoma GWASdb SNP-Disease Associations 1.0 0.675077 GSE226316_11_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_16832_OE_Myc_SRP250081 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.52731 GSE144500_8_v_2_ventx_human RummaGEO Gene Perturbation Signatures 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null DNMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85424 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.11095 Perturb_2152_KO_Trp53_DRP003641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.81053 NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.2482 subthalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.87315 renal neoplasm GWASdb SNP-Phenotype Associations 1.0 0.377222 H2461 COSMIC Cell Line Gene Mutation Profiles 1.0 null BLOC1S4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33878 respiratory system cancer GWASdb SNP-Disease Associations 1.0 0.2799 Perturb_3810_KO_Axin1_SRP358586 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.97815 GSE200352_5_v_8_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null Vagina TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 layer III of piriform cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.94568 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6067 SMO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98382 TMEM30A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57858 heart muscle HPA Tissue Protein Expression Profiles -1.0 -0.936627 rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.029643 disease of mental health GWASdb SNP-Disease Associations 1.0 0.107491 ADM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78994 GSE89154_1_v_2_proscillaridin_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_4688_KD_Srsf3_SRP059321 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.231 PTAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5048 MYO10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.096 GSE172494_3_v_1_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null Joubert syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.154 ERCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44698 GSE153189_1_v_3_interferon gamma_mouse RummaGEO Drug Perturbation Signatures 1.0 null raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.09492 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15699 REPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65866 Perturb_13840_KD_Ebp1_SRP279969 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.48346 AGAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53959 ZC3H12C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.782 Schizophrenia DisGeNET Gene-Disease Associations 1.0 null TAL1 ENCODE Transcription Factor Targets 1.0 null STARD3NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96181 L-363 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Perturb_4682_KO_Mll2_SRP189864 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.22528 paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03885 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943239 GSE220520_3_v_4_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null RYBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83938 COPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15546 Uterus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HCC38 CCLE Cell Line Gene Expression Profiles 1.0 1.63943 GSE239578_0_v_4_cxadr_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_11123_KO_Mettl3_SRP363782 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.14489 GSE96093_1_v_0_abca1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE184479_3_v_2_aim2_mouse RummaGEO Gene Perturbation Signatures -1.0 null MPP-89 COSMIC Cell Line Gene Mutation Profiles 1.0 null MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Familial isolated trichomegaly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.054 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08186 Perturb_17346_KO_Srsf1_SRP219203 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.56376 outer CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.889438 bilirubin metabolic disorder GWASdb SNP-Disease Associations 1.0 3.42593 TUBB2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88885 GSE173911,GSE173917_0_v_1_morc3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE221327_10_v_9_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 8.89499 GSE184884_4_v_1_gps2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PAFAH1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82857 carboplatin_homo sapiens_gpl570_gse13525 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MADD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20274 SPDEF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8611 Perturb_14937_KD_Pnky_SRP053095 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.42015 Perturb_17572_KD_Hnrnpk_SRP157112 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.45617 Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.0228 oral mucosa HPA Tissue Protein Expression Profiles 1.0 0.994474 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51052 Bilirubin levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.730103 EW-12 COSMIC Cell Line Gene Mutation Profiles 1.0 null mood disorder GWASdb SNP-Disease Associations 1.0 0.331593 NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.712 LRRC40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41701 ZNF627 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00893 schizophrenia GWASdb SNP-Phenotype Associations 1.0 1.19366 MAP6D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72398 PCI-15A COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_4732_KO_Ssu72_SRP167695 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.89935 ZSCAN16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15186 GSE223540_0_v_3_anxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92201 GSE180200,GSE180201_5_v_11_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.83787 GSE215351,GSE215794_2_v_3_kdm8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE111660_4_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1569 PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_11203_KO_Mettl3_SRP322470 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.92286 PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF Rummagene Transcription Factor Associations 2026 1.0 null GSE197564,GSE198513_2_v_0_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.033 abnormality of female internal genitalia GWASdb SNP-Phenotype Associations 1.0 0.166571 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ISG20L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32056 RD COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE65617_5_v_1_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903849 GPATCH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23139 SBC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE142684_4_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE250534_0_v_3_cabergoline_mouse RummaGEO Drug Perturbation Signatures -1.0 null TCF7L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05123 Inner acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.103 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14215 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.56224 MDA-MB-175-VII COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_8708_KD_Irf2_SRP193480 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.43741 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93755 Perturb_5173_KD_Hnrnpk_SRP078486 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.8116 disease of cellular proliferation GWASdb SNP-Disease Associations 1.0 0.151954 AP5Z1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85994 Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.979 INO80C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.44033 HS695T CCLE Cell Line Gene Expression Profiles -1.0 -1.98402 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81024 SK-N-AS COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE213632_0_v_6_acod1_mouse RummaGEO Gene Perturbation Signatures 1.0 null hyperbilirubinemia GWASdb SNP-Phenotype Associations 1.0 3.32303 GSE208096_1_v_0_progesterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null Perturb_5540_KO_Fh1_ERP138019 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.38176 GSE224969,GSE224971_0_v_1_chtop_mouse RummaGEO Gene Perturbation Signatures -1.0 null RUFY3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35245 COX7C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16364 GSE226285_3_v_1_glutathione_human RummaGEO Drug Perturbation Signatures 1.0 null hippocampus HPA Tissue Protein Expression Profiles -1.0 -0.936627 GSE74490_0_v_1_triptolide_mouse RummaGEO Drug Perturbation Signatures 1.0 null Oral mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Perturb_16750_KO_Rc3h1/Rc3h2/Zc3h12a_SRP268288 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.61815 MRPL14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26972 Perturb_9459_KO_Srsf3_SRP143519 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.97944 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15823 METTL21EP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6985 Brain - Putamen (basal ganglia) GTEx Tissue Gene Expression Profiles 2023 1.0 0.362209 GSE114992,GSE114993_9_v_6_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_17108_KO_Fam26f_ERP105671 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.34116 outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.920693 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.935631 GSE248858_1_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null PRPF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28571 limitans nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.979205 outer SZ in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07028 GSE221327_1_v_0_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null GSE223008_9_v_1_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null G-402 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.08479 TMEM250 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5837 MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM136A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19352 ESS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_4566_KD_Setdb1_SRP172038 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.7826 Perturb_13377_KO_Sox10_SRP267687 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.61983 Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.7193 outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6628 H4C3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27793 ENTPD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46569 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.986969 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.78753 SLC18A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45393 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848188 Perturb_13336_KD_Pou2f1_SRP149831 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.38622 Perturb_4514_KD_Tip60_SRP081300 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.78383 OST4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42239 GSE60837_2_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE153189_2_v_3_interferon gamma_mouse RummaGEO Drug Perturbation Signatures 1.0 null LMNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25907 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887028 PRKAG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18095 GSE114992,GSE114993_9_v_2_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.227551 MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30721 SIN3A ENCODE Transcription Factor Targets 1.0 null GSE77178_1_v_3_ccnd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CHD1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69641 Perturb_16759_KO_Trp53_DRP003641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.35411 KIF3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57961 hematologic cancer GWASdb SNP-Disease Associations 1.0 0.115863 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.34045 Perturb_13179_KO_Mof_SRP060636 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.05875 Perturb_5872_KD_Nudt21_SRP336206 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.82764 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1083 PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX Rummagene Transcription Factor Associations 2026 1.0 null PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null NB17 COSMIC Cell Line Gene Mutation Profiles 1.0 null Large cell neuroendocrine carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.27 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08078 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.03345 Perturb_2378_KD_Cdk8_SRP292215 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.15509 Perturb_15705_KO_Rnf20_SRP304263 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.17481 GSE142210_3_v_8_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null Total bilirubin levels in HIV-1 infection GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.552288 MDAMB175VII CCLE Cell Line Gene Expression Profiles 1.0 1.97138 496100532_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.54644 Perturb_5266_KD_neg_SRP331021 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.25204 UQCC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77618 depression GWASdb SNP-Phenotype Associations 1.0 0.649829 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.116043 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50009 GSE226285_3_v_1_nr0b1_human RummaGEO Gene Perturbation Signatures 1.0 null thoracic cancer GWASdb SNP-Disease Associations 1.0 0.439439 morphological abnormality of the central nervous system GWASdb SNP-Phenotype Associations 1.0 0.082185 inner CP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31436 PACS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40676 LMTK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.55859 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11693 Arid3b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.7876 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06505 Brain - Cortex GTEx Tissue Gene Expression Profiles 2023 1.0 1.9148 TCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1464 XPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09316 PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-PHOX2B-fromNode_PHOX2B Rummagene Transcription Factor Associations 2026 1.0 null DNAJC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13568 Perturb_1071_KO_miR34a_SRP212898 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.56701 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40137 GSE139239_1_v_5_ddr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PGRMC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65435 outer CP in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17444 Perturb_16580_KO_Ep300_SRP174041 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.6426 SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69868 Lef1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.7428 GSE153189_1_v_0_stat1_mouse RummaGEO Gene Perturbation Signatures 1.0 null IM-95 COSMIC Cell Line Gene Mutation Profiles 1.0 null YY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78275 GSE114258_3_v_2_foxk1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE63048_11_v_8_morc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE129241_4_v_0_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null GSE211744_8_v_1_gdf15_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE171179,GSE171181_0_v_1_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null BRPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44622 Dermal dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.904 POU2AF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11033 GSE180200,GSE180201_2_v_9_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null MY-M12 COSMIC Cell Line Gene Mutation Profiles 1.0 null B4GALT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74072 soft tissue HPA Tissue Protein Expression Profiles -1.0 -2.49562 GSE223893_11_v_10_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null KIF21B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45203 GSE224004,GSE224005_0_v_1_chd4_human RummaGEO Gene Perturbation Signatures -1.0 null GSE246195,GSE246305_1_v_0_sin3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null CDCP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31721 GSE221327_1_v_2_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null GSE220520_3_v_9_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.869168 ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2928 Nr1h3::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.9511 CCK-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null inner CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30374 MKNK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89495 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.979 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.3699 GSE193258,GSE193259_5_v_6_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null KYM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null IGR-37 COSMIC Cell Line Gene Mutation Profiles 1.0 null TE-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_5044_KO_Ssu72_SRP167695 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.40266 outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01106 ME1 CCLE Cell Line Gene Expression Profiles -1.0 -2.02672 SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null ERCC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02729 Coloboma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.158 CLASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81809 RCM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H2369 COSMIC Cell Line Gene Mutation Profiles 1.0 null SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null neoplasm by histology GWASdb SNP-Phenotype Associations 1.0 0.193832 PLPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12236 WASL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22997 neuroectodermal neoplasm GWASdb SNP-Phenotype Associations 1.0 0.292668 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -1.89556 ZNF768 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.5846 parathyroid gland HPA Tissue Protein Expression Profiles -1.0 -0.936627 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14456 OVCAR-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZBTB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4104 OV7 CCLE Cell Line Gene Expression Profiles -1.0 -1.45871 Perturb_10596_KO_Nr1h3/Nr1h2_SRP351084 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.64593 sp1_22099172_dental_follicle_cell_gof_human_gpl11532_gse31628 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.101512 Perturb_5344_KO_Ilf2_SRP100469 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.20986 GSE74251_0_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null RABGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66804 Perturb_9521_KO_Dync2h1_SRP131479 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.50722 RS4-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE193685_2_v_3_il11_mouse RummaGEO Gene Perturbation Signatures -1.0 null Esophageal squamous cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.943 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TE-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null EW-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H510A COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR Rummagene Transcription Factor Associations 2026 1.0 null NF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86499 deep layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.893744 neoplasm of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.292668 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.77827 GSE131887_5_v_3_doxycycline_mouse RummaGEO Drug Perturbation Signatures -1.0 null Perturb_6955_KO|KD_Titin|Rbm20_ERP122940 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.90082 GSE114992,GSE114993_8_v_5_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null cumulus-oocyte complex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.779 CTSF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4286 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902767 GSE122101,GSE122103_0_v_1_ssu72_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE153189_1_v_0_interferon gamma_mouse RummaGEO Drug Perturbation Signatures 1.0 null Perturb_16720_Mut_Lmna_SRP309326 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.95271 MDK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86016 SNU840 CCLE Cell Line Gene Expression Profiles -1.0 -1.51339 HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7895 orofacial cleft GWASdb SNP-Disease Associations 1.0 0.756064 GSE144443_0_v_3_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null KYSE-30 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_17263_KO_Gja1_SRP247546 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.39944 GSE200352_1_v_8_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null kidney cancer GWASdb SNP-Disease Associations 1.0 0.439439 Perturb_10700_OE_Yap1_SRP132526 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.28887 NB13 COSMIC Cell Line Gene Mutation Profiles 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null RBMX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40668 Perturb_16947_OE_Mir181a1_SRP359086 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.26232 KYAE-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null MESSA CCLE Cell Line Gene Expression Profiles 1.0 3.40768 GSE92614_1_v_0_pten_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE58724_3_v_4_oxymetholone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Median body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.734 ENO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08569 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.955599 Lung TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE152441,GSE152442_1_v_3_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE163862_1_v_3_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null NPIPB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12422 GSE114992,GSE114993_4_v_6_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_1207_KO_Sp4/Sp1_SRP302435 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.25647 GSE188814,GSE188854_0_v_1_wtap_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_11156_KO_Tsc1/p62_SRP069010 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.99156 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31031 TBX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0272 Perturb_10829_KO_Xbp1_SRP262377 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.34328 EHEB COSMIC Cell Line Gene Mutation Profiles 1.0 null MAPK8IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01134 Perturb_3195_KO_Poldip2_SRP302743 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.28108 ZNF772 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67023 GTPBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39327 JAR COSMIC Cell Line Gene Mutation Profiles 1.0 null DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null RT4 COSMIC Cell Line Gene Mutation Profiles 1.0 null TCF7-22412390-EML-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null PUS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40058 uterine cancer GWASdb SNP-Disease Associations 1.0 0.439439 endometrial carcinoma GWASdb SNP-Phenotype Associations 1.0 0.578475 Perturb_13457_OE_Smn1_SRP366489 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.58706 TOP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4309 ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8224 GSE101767_1_v_0_wdr11_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF611 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27981 Perturb_4240_KO_Clpp_SRP116036 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.76791 TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0789 UBQLN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80959 GSE214583,GSE214585_1_v_0_steap1_human RummaGEO Gene Perturbation Signatures 1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39338 Perturb_13456_OE_Smn1_SRP366489 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.9231 GSE92589_0_v_1_sirolimus_mouse RummaGEO Drug Perturbation Signatures -1.0 null NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900395 SF126 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE200352_10_v_6_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE180200,GSE180201_5_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.8111 NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943239 Perturb_12854_KD_Pdx1_SRP149543 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Perturb_5023_KO_4930500J02Rik_SRP072189 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.10323 neoplasm of the breast GWASdb SNP-Phenotype Associations 1.0 0.578475 RARRES1_KD_GDS4818_314_human_SUM149 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25229 Perturb_4695_KD_Srsf3_SRP059321 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.06012 Uterine cervix TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abnormality of the urinary system GWASdb SNP-Phenotype Associations 1.0 0.844241 GSE218879_1_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null KYSE-520 COSMIC Cell Line Gene Mutation Profiles 1.0 null ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9966 neoplasm of the genitourinary tract GWASdb SNP-Phenotype Associations 1.0 0.274122 SPEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96379 HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08197 MAP2K7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95595 GDM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null LARGE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92441 neoplasm of the lung GWASdb SNP-Phenotype Associations 1.0 0.578475 MZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04138 Perturb_4567_KD_Smc1a_SRP172038 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.34769 Ileocecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE135400_2_v_0_kdm1b_human RummaGEO Gene Perturbation Signatures 1.0 null GSE228413_2_v_1_mavs_mouse RummaGEO Gene Perturbation Signatures -1.0 null MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05569 disease GWASdb SNP-Disease Associations 1.0 0.229593 NB1 COSMIC Cell Line Gene Mutation Profiles 1.0 null C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06018 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.68736 PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96792 PMC8596853-41586_2021_4103_MOESM4_ESM.xlsx-ST12-Unnamed_2_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE253056_0_v_1_erythropoietin_mouse RummaGEO Drug Perturbation Signatures 1.0 null H1-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1114 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.20446 SJSA-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_12720_KD_KMT2C_SRP110043 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Bilirubin Level Result DisGeNET Gene-Phenotype Associations 1.0 null PLEKHA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89513 NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4645 GSE114992,GSE114993_4_v_5_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null NUCB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.90326 GSE113817_2_v_1_bach1_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_987_KO_Eed_SRP092111 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.16008 Perturb_28_OE_Smad1_SRP217699 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.38044 Perturb_5883_KD_Ift88_SRP188845 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.55633 foxa2_20483781_p15_lung_lof_mouse_gpl1261_gse19204 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.158596 GSE255432_7_v_3_imeglimin_mouse RummaGEO Drug Perturbation Signatures 1.0 null NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.5545 Perturb_4782_KD_Trim24/Trp53_ERP019861 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.19804 CTNNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84713 NR1H4::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2057 NCI-H1770 COSMIC Cell Line Gene Mutation Profiles 1.0 null SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.891666 nasopharynx HPA Tissue Protein Expression Profiles 1.0 0.994474 Perturb_9563_KO_Ogt_SRP110508 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.23591 Cholelithiasis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.979 ATAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69133 GSE138841_0_v_1_trim6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE159148_0_v_1_sdc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6041 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2801 ARID3A JASPAR Predicted Transcription Factor Targets 1.0 null Perturb_2954_KD_Mll3/Mll4_SRP029581 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Perturb_15669_KD_Hnrnpf_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.7752 RERF-LC-FM COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE175787_11_v_0_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Colon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.918327 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2993 Perturb_9562_KO_Ogt_SRP110508 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.19648 MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.971999 Perturb_13129_KD_Dnmt1_SRP115380 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.73892 2q37 copy number variation syndrome WikiPathways Pathways 2024 1.0 null GSE241701_1_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null PPP1R14B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61701 GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_15675_KD_Hnrnpf_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.70097 Perturb_166_KD_Mir21_SRP361611 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.38514 MOLT-16 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE186633_2_v_0_chd1_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_11910_KD_Hmga2_SRP029975 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 17.9547 Hypoglossal nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.781 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.17745 GSE174424,GSE174425_5_v_1_cnot8_mouse RummaGEO Gene Perturbation Signatures -1.0 null SUDHL4 CCLE Cell Line Gene Expression Profiles 1.0 1.36865 DOHH-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE142684_3_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null SK-MM-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_5874_KD_Aldoa_SRP385857 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.91852 Familial medullary thyroid carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.008 SU-DHL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PGR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5763 Perturb_16705_KO_Gb6_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.52332 Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 59.3557 GCSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53504 Perturb_10660_KD_Urod_SRP226321 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE89767_1_v_5_cebpa_mouse RummaGEO Gene Perturbation Signatures 1.0 null ovary HPA Tissue Protein Expression Profiles -1.0 -0.936627 NCI-H2135 COSMIC Cell Line Gene Mutation Profiles 1.0 null RKN COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_3830_KO_Slc5a8_SRP182951 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.47691 NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.6933 H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null b-cell lymphoma GWASdb SNP-Disease Associations 1.0 0.439439 DYNLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30951 GSE114992,GSE114993_8_v_2_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE221327_10_v_11_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null ZNF473 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64148 GSE112762,GSE112767_2_v_0_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC9263655-mmc3.xlsx-ZNF436-AS1-Prediction_catRAPID_ZNF436 Rummagene Transcription Factor Associations 2026 1.0 null STAMBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16019 physical disorder GWASdb SNP-Disease Associations 1.0 0.382855 SORD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86667 SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null Glutamatergic neuron_Cerebellum_Mouse CellMarker Gene-Cell Type Associations 1.0 null GSE114992,GSE114993_7_v_5_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7819 A253 CCLE Cell Line Gene Expression Profiles 1.0 2.25276 SNX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45506 WHAMM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77615 GSE246195,GSE246305_2_v_5_sin3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null Ciliopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.263 abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.301683 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.971999 Perturb_15034_KD_WDR5_SRP024294 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.64637 Perturb_4366_KO_Qki_SRP153187 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.62243 Perturb_15734_KO_Kmt2d_SRP058264 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.88542 TMK-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pernicious anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.293 Perturb_17_OE_Carhsp1_SRP217699 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.5662 ZNF354B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55048 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.83787 GSE80098,GSE80366_0_v_5_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE246911,GSE246913_4_v_1_arid1a_mouse RummaGEO Gene Perturbation Signatures -1.0 null BAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27732 Perturb_9467_KO_Dbx1_SRP353027 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.63037 Perturb_17439_KO_Uqcrfs1_SRP279621 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.82511 ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null SUDHL10 CCLE Cell Line Gene Expression Profiles 1.0 1.90628 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24914 Perturb_9717_KD_Basp1_SRP126738 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.99465 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null female reproductive organ cancer GWASdb SNP-Disease Associations 1.0 0.321382 GSE122101,GSE122103_3_v_1_ssu72_mouse RummaGEO Gene Perturbation Signatures 1.0 null TCP10L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26109 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06505 SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08078 TBX21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55736 ZBTB25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31552 small intestine HPA Tissue Protein Expression Profiles 1.0 0.994474 ATP6V0A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52663 abnormal internal genitalia GWASdb SNP-Phenotype Associations 1.0 0.155953 reproductive organ cancer GWASdb SNP-Disease Associations 1.0 0.218417 glioblastoma GWASdb SNP-Phenotype Associations 1.0 0.578475 SW626 COSMIC Cell Line Gene Mutation Profiles 1.0 null NFATC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10041 CCDC87 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6947 GSE175571_3_v_2_acsl6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_12695_OE_Hoxb13_SRP250504 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Sperm midpiece COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.045 Perturb_15647_KD_Hnrnpm_SRP222089 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.14417 ZKSCAN1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GOLGB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12307 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.435 DCP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93483 Perturb_13417_KO_Coro1_SRP168748 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.30377 Perturb_11282_KO_Hlf/Dbp/Tef_SRP218451 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.47984 outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.53121 J82 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null IL18BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2053 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.035082 GSE245418_0_v_2_cd109_human RummaGEO Gene Perturbation Signatures 1.0 null Cecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 testosterone_mus musculus_gpl1261_gse17553 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_1261_KO_Ahnak_SRP307472 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.28894 GSE157594_5_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null NELFE ENCODE Transcription Factor Targets 1.0 null Sperm plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.759 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7243 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16459 Colorectal Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null GSE115363_2_v_5_esrrb_mouse RummaGEO Gene Perturbation Signatures 1.0 null ARFRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13016 AKAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82477 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -1.85936 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25022 agranular insular cortex (area Iag) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04923 GSE247764_0_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE76771_1_v_3_atf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null ERO1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35691 PIGG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98229 urinary system cancer GWASdb SNP-Disease Associations 1.0 0.321382 cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null GSE241036_4_v_2_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null EMC-BAC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ANKLE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04397 PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null DNAAF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68526 Perturb_16590_KO_Srsf2_SRP133673 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.51258 abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.052979 genital neoplasm GWASdb SNP-Phenotype Associations 1.0 0.257619 Vermiform appendix TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null Perturb_10927_KO_Mettl3_SRP363782 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.33788 GSE44157,GSE44163_3_v_0_nr6a1_mouse RummaGEO Gene Perturbation Signatures -1.0 null DNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95115 Perturb_11296_KO_Hlf/Dbp/Tef_SRP218451 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.35105 CALR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90694 lung carcinoma GWASdb SNP-Disease Associations 1.0 0.371746 inner CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.56471 disease of metabolism GWASdb SNP-Disease Associations 1.0 1.52066 abnormality of the head GWASdb SNP-Phenotype Associations 1.0 0.096543 496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.12234 Perturb_10727_KO_Mettl14_SRP282531 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 17.8996 Perturb_213_OE_Mettl7a1_SRP357594 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.36555 ZNF792 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60296 GATA2_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null glioma GWASdb SNP-Phenotype Associations 1.0 0.331537 GSE157777_2_v_3_foxa3_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null FUS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56861 major depressive disorder GWASdb SNP-Disease Associations 1.0 0.750866 lung cancer GWASdb SNP-Disease Associations 1.0 0.321382 EW-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null NSUN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02265 GSE207301,GSE207303_1_v_2_tp53bp2_human RummaGEO Gene Perturbation Signatures 1.0 null Bronchus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Metabolic Syndrome X DisGeNET Gene-Disease Associations 1.0 null APIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73086 LBR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56337 LUC7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01096 GSE226285_3_v_0_glutathione_human RummaGEO Drug Perturbation Signatures 1.0 null GSE188869,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC6587279-13099_2019_311_MOESM2_ESM.xlsx-AR_Maternal_N-1-Ensembl_Genes_90_Ensembl_AR Rummagene Transcription Factor Associations 2026 1.0 null P2RY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41545 Perturb_3391_KO_G6pd1_SRP305179 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.60009 Perturb_657_KD_lncRNA_141992_SRP093784 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.40321 GSE223540_1_v_3_anxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null liver GTEx Tissue Gene Expression Profiles 1.0 0.965061 GSE247764_3_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.57153 Perturb_5220_KO_Tdg_SRP171121 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.19712 GSE137818_5_v_0_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC8898985-NIHMS1734801-supplement-1734801_Supp_table.xlsx-5B-Hypothalamic_Vglut2_Cnr1_Ninl_Rfx5_Zfp346_Neuron_ZNF346 Rummagene Transcription Factor Associations 2026 1.0 null GSE196699_2_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZBTB32 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2277 GSE246461,GSE246463_5_v_0_mecp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null kidney disease GWASdb SNP-Disease Associations 1.0 0.958374 GSE171177,GSE171181_1_v_0_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null PCDHB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49937 Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.1391 Perturb_5730_KO_mir155_SRP222324 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.84645 Perturb_14107_KO_Setd2_SRP220107 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.73133 496100422_TCx_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.03387 HN cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.095 CYRIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49589 496100414_TCx_probable Alzheimer's disease_no TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.1998 Perturb_6353_KO_Smn_SRP253847 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.17648 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GATA2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23483 DV90 CCLE Cell Line Gene Expression Profiles 1.0 1.80099 MHH-NB-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_12886_KD_Setd2_SRP132773 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.7251 NCI-H820 COSMIC Cell Line Gene Mutation Profiles 1.0 null DYNC1LI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8316 PHOX2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24729 Perturb_1893_Mut_Trem2_SRP173901 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.67475 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.72322 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null H2591 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE110178_2_v_6_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures -1.0 null SISO COSMIC Cell Line Gene Mutation Profiles 1.0 null THRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72324 MZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.845393 SP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0281 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_5869_KD_Cpsf7_SRP336206 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.39692 SW780 CCLE Cell Line Gene Expression Profiles 1.0 1.69693 PEX26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5127 PRKCSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78487 STPG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29764 GSE114992,GSE114993_4_v_2_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE180813,GSE180815_1_v_0_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null inner CP in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.923963 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null UGCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82489 Zfp809 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.588 HUH-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ADAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93869 Perturb_13285_KO_Mettl14_SRP182641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.07541 Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 45.6905 GSE133516_0_v_6_kat7_human RummaGEO Gene Perturbation Signatures 1.0 null UBE2G1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.04511 GSE110178_2_v_0_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures -1.0 null Perturb_5256_KO_Morc3_SRP318571 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.38501 Photoreceptor outer segment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.055 NCI-SNU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Oral squamous cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.886 MLL1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.851 ADRA2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07334 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1709 BL1690 (MAD1L1) NURSA Protein Complexes 1.0 null WDR37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96508 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.93001 psychotic disorder GWASdb SNP-Disease Associations 1.0 0.391182 TM2D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61813 GSE221327_10_v_0_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null ZFPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98728 Perturb_11161_KO_Setd8_SRP102934 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.38925 Perturb_11318_KO_Nr1d1/Nr1d2_SRP241717 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.8417 BICR 10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18102 MIEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40394 Perturb_4985_KO_Ythdc1_SRP212677 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.8462 NR4A2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.653 lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -0.936627 GSE133329_0_v_3_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_12627_KO_Bag6_ERP110252 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.63131 GSE153189_1_v_3_stat1_mouse RummaGEO Gene Perturbation Signatures 1.0 null golgi apparatus LOCATE Predicted Protein Localization Annotations 1.0 null OE33 COSMIC Cell Line Gene Mutation Profiles 1.0 null CCK81 CCLE Cell Line Gene Expression Profiles 1.0 1.46041 duodenum HPA Tissue Protein Expression Profiles 1.0 0.994474 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.854971 Perturb_11229_Mut_Celf1_SRP076406 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.54333 UTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67743 PAPOLG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07098 Perturb_15269_KO_Trp53_SRP187559 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.52404 NDST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15006 496100460_TCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.75981 malignant glioma GWASdb SNP-Disease Associations 1.0 0.439439 GSE144443_5_v_6_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null Perturb_13077_KO_Cry2_SRP091906 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.92156 IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10905 ZNF726 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86165 GSE228413_2_v_3_mavs_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE211215_1_v_0_pemetrexed_human RummaGEO Drug Perturbation Signatures 1.0 null FCHSD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23948 renal cell carcinoma GWASdb SNP-Phenotype Associations 1.0 0.578475 C14orf93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86564 FSTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08894 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null PMC11187145-41525_2024_418_MOESM1_ESM.pdf-18-ENSG00000198046_ZNF667 Rummagene Transcription Factor Associations 2026 1.0 null OCILY10 CCLE Cell Line Gene Expression Profiles 1.0 1.39144 GSE109565_12_v_4_glyphosate_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_11290_KO_Bmal1_SRP153814 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.92318 ACTR5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23993 Perturb_16604_KO_Phb_SRP229743 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.27868 Perturb_12086_OE_Esr1_SRP050547 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.90897 Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.0776 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.250316 PTP4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52834 Perturb_4602_KO_Mst_SRP246200 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.31156 GSE88819_1_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_3486_KO_Mettl3_SRP273291 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04354 GSE155755,GSE155757_0_v_1_ncoa6_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_5245_KO_Ssrp1_SRP276644 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.7068 GSE221327_1_v_11_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null rectum HPA Tissue Protein Expression Profiles 1.0 0.994474 INCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86595 GSE129370_2_v_3_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null renal cell carcinoma GWASdb SNP-Disease Associations 1.0 0.675077 Perturb_3121_KO_Slc45a3_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.09809 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2801 Perturb_13448_OE|KD_PAX2|PTEN_SRP279768 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.91162 CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943239 abnormality of the breast GWASdb SNP-Phenotype Associations 1.0 0.377222 GSE221327_5_v_0_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF Rummagene Transcription Factor Associations 2026 1.0 null SK-GT-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null CAMA-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE157777_2_v_0_foxa3_mouse RummaGEO Gene Perturbation Signatures -1.0 null ALL-PO COSMIC Cell Line Gene Mutation Profiles 1.0 null HRH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13004 ASH-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.830511 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.902767 GSE180185_4_v_8_setbp1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE131798,GSE131804_1_v_0_igf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1793 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null mantle cell lymphoma GWASdb SNP-Disease Associations 1.0 0.675077 GSE58724_1_v_4_oxymetholone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Tongue carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.462 GSE232631_0_v_2_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.193205 TCF7 ChEA Transcription Factor Targets 1.0 null NCIH1836 CCLE Cell Line Gene Expression Profiles -1.0 -2.704 abnormality of the upper urinary tract GWASdb SNP-Phenotype Associations 1.0 0.216685 lymphoma GWASdb SNP-Disease Associations 1.0 0.2799 Perturb_2272_KO_Mettl3_SRP110576 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.7936 SK-PN-DW COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_3454_KO_Ugt8_SRP073495 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.59881 IRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32762 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE225218_9_v_3_abcb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE126621,GSE126920_1_v_3_dppa4_mouse RummaGEO Gene Perturbation Signatures 1.0 null RCC-JF COSMIC Cell Line Gene Mutation Profiles 1.0 null RAG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2346 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.979 SLC27A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84733 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96792 ZNF550 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28461 MHH-PREB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE166317_3_v_0_j147_mouse RummaGEO Drug Perturbation Signatures 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null GSE190322,GSE190324_3_v_4_rbm4_mouse RummaGEO Gene Perturbation Signatures -1.0 null BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3757 renal carcinoma GWASdb SNP-Disease Associations 1.0 0.675077 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27829 CAKI-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63724 GSE145639_1_v_2_adar_human RummaGEO Gene Perturbation Signatures -1.0 null hematological neoplasm GWASdb SNP-Phenotype Associations 1.0 0.166571 Perturb_13532_KO_Mbnl3_SRP103934 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.752 SEC16A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97598 MRPS18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51246 BEX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00846 Perturb_10190_KD_AES_SRP073721 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.76003 POU5F1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71788 PMC8330021-13058_2021_1455_MOESM8_ESM.xlsx-MSC_HEATMAP-Unnamed_0_MSC Rummagene Transcription Factor Associations 2026 1.0 null TRAPPC2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3076 SCC4 CCLE Cell Line Gene Expression Profiles 1.0 1.84825 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96792 GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4932 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3793 TE-441-T COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_5981_KD_XRN2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.52495 FAM171B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38803 bronchus HPA Tissue Protein Expression Profiles 1.0 0.994474 GSE207301,GSE207303_1_v_3_tp53bp2_human RummaGEO Gene Perturbation Signatures 1.0 null vagina HPA Tissue Protein Expression Profiles 1.0 0.994474 muscle GTEx Tissue Gene Expression Profiles -1.0 -0.851879 chr2_233799983_G_A_b38 GTEx eQTL 2025 1.0 8.7603 GSE195582_3_v_1_pim1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_4812_KO_Stat5b_ERP004375 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.90771 chr2_233756852_C_A_b38 GTEx eQTL 2025 1.0 1.61781 NAA20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35186 Mouth TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 mental depression GWASdb SNP-Disease Associations 1.0 0.449075 GSE112760,GSE112767_4_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF860 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55332 LTBR_INHIBITION - 3 Days_GDS2005_730_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE161864,GSE161866_4_v_3_ror2_human RummaGEO Gene Perturbation Signatures -1.0 null LC-1-SQ COSMIC Cell Line Gene Mutation Profiles 1.0 null Hair greying GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.51549 caudal subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.915458 H3K9me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4603_KO_Mst_SRP246200 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.87626 ETK-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE214596,GSE214598_1_v_0_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null GNAI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21415 GSE81193_3_v_4_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE200352_5_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE129287_0_v_1_cd200_mouse RummaGEO Gene Perturbation Signatures -1.0 null USF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2991 Perturb_5305_KO_Dnmt1/Dnmt3a/Dnmt3b_SRP101434 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.6325 Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.4196 GSE151829,GSE151831_1_v_0_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null BRCA1_DEPLETION_GDS3791_38_human_Hela GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE198165,GSE198166_0_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null IST-SL1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-CESC_AND_UCEC_NOT_BRCA_NOT_UCS_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null PNPLA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9134 ECD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5192 AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21353 Perturb_11171_KO_Tug1_SRP176442 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.03281 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848188 Perturb_17079_KO_Nhedc2_ERP105671 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.03731 Integument TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 0.145941 GSE200673,GSE200691_2_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Bilirubin dbGAP Gene-Trait Associations 1.0 1.49075 ST486 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE80098,GSE80366_0_v_4_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE203308_14_v_0_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null LCN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07215 NCIH1395 CCLE Cell Line Gene Expression Profiles 1.0 2.04754 ES6 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null OS-RC-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_11293_KO_Nr1d1/Nr1d2_SRP241717 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.99941 NPIPA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68293 GSE122101,GSE122103_0_v_4_ssu72_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of the genital system GWASdb SNP-Phenotype Associations 1.0 0.095528 abnormal genital system morphology GWASdb SNP-Phenotype Associations 1.0 0.110117 neoplasm of the central nervous system GWASdb SNP-Phenotype Associations 1.0 0.257619 GSE221327_1_v_9_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.15635 PLD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94431 KAT2A ENCODE Transcription Factor Targets 1.0 null GSE58724_1_v_0_oxymetholone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Perturb_3102_KO_N4bp3_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.29393 immune system cancer GWASdb SNP-Disease Associations 1.0 0.115863 SKG-IIIA COSMIC Cell Line Gene Mutation Profiles 1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.894297 496100368_PCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.02767 GSE75976_3_v_6_abl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE154464_1_v_2_cdk6_mouse RummaGEO Gene Perturbation Signatures -1.0 null FIBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36174 CHCHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97439 Perturb_4988_KO_Ythdc1_SRP212677 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.85263 MPPE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59246 PJA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24272 Perturb_11209_KO_Mettl14_SRP339507 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.586 GSE169697,GSE169725_0_v_5_prrx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SEMA3F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75669 CAL33 CCLE Cell Line Gene Expression Profiles -1.0 -1.6839 HCFC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.14239 CCDC34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49689 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15699 SNU899 CCLE Cell Line Gene Expression Profiles 1.0 1.41102 Perturb_12568_KD_Sufu_SRP194252 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 RGPD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6701 496100351_FWM_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.65273 abnormality of the mouth GWASdb SNP-Phenotype Associations 1.0 0.153286 496100458_FWM_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.09764 GSE247764_1_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_3828_KO_Trp53_DRP003641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.29004 GSE200352_1_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCIH1184 CCLE Cell Line Gene Expression Profiles -1.0 -1.69186 Perturb_2273_KO_Mettl3_SRP110576 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25178 GSE144443_0_v_6_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null MOGS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30721 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.68736 Perturb_13276_KO_Dicer1_SRP226863 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 LACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78201 TNFRSF21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46944 STAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43007 YKG-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87376 496100322_FWM_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.47391 GSE111247_2_v_3_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_12_KD_Ago1/Ago2_SRP133220 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.54126 breast cancer GWASdb SNP-Disease Associations 1.0 0.675077 MYH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69273 ZBTB49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58739 abnormality of the kidney GWASdb SNP-Phenotype Associations 1.0 0.216685 THBS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17429 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10454 Perturb_2377_KD_Cdk8_SRP292215 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.32167 RH41 CCLE Cell Line Gene Expression Profiles -1.0 -1.78132 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.596 RNF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7738 Perturb_73_KD_Ror2_SRP322393 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.79584 Perturb_13610_KD_Srsf11_SRP136943 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.1852 Perturb_203_KD_Id1/ld3_SRP193147 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.26759 GSE84462,GSE84762_0_v_7_ezh2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE126777_0_v_1_otub1_mouse RummaGEO Gene Perturbation Signatures -1.0 null METTL16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72314 Perturb_12696_KO_Ezh2_SRP222765 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.39168 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.3118 NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.41528 GSE157904_3_v_1_doxorubicin_mouse RummaGEO Drug Perturbation Signatures 1.0 null HDQ-P1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE254517_1_v_0_irf7_mouse RummaGEO Gene Perturbation Signatures 1.0 null ADCY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70764 AFF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30355 SP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25177 abnormality of the glial cells GWASdb SNP-Phenotype Associations 1.0 0.331537 abnormality of the female genitalia GWASdb SNP-Phenotype Associations 1.0 0.166571 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.56984 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.971999 IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27697 RNF41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7077 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.70213 Perturb_11287_KO_Hlf/Dbp/Tef_SRP218451 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.32992 Bilirubin Measurement DisGeNET Gene-Phenotype Associations 1.0 null NCI-H1155 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE200352_11_v_6_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null H2373 COSMIC Cell Line Gene Mutation Profiles 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.971999 GSE153189_2_v_3_stat1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE206226_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null SARAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76214 abnormality of the endometrium GWASdb SNP-Phenotype Associations 1.0 0.578475 Perturb_14683_KO_Dpy30_SRP320666 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.17094 GSE114258_1_v_0_foxk1_mouse RummaGEO Gene Perturbation Signatures 1.0 null NHLRC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50583 inferior olive, dorsal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.871204 Imago TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.842 DCAKD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12397 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28309 SSBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88456 PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX Rummagene Transcription Factor Associations 2026 1.0 null PLXNA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7706 GSE165174,GSE165175_0_v_1_trametinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09365 lung HPA Tissue Protein Expression Profiles -1.0 -1.7898 GSTK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57886 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE103372_0_v_3_smad1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE114992,GSE114993_7_v_3_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null organ system cancer GWASdb SNP-Disease Associations 1.0 0.145498 midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.98384 Perturb_2379_KD_Cdk8_SRP292215 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.93243 PMC11187145-41525_2024_418_MOESM1_ESM.pdf-18-ZNF667_ZNF667 Rummagene Transcription Factor Associations 2026 1.0 null UCMA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61352 GSTM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70107 Perturb_3730_KO_Atf7ip_SRP327190 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.6026 Perturb_13800_OE|KO|KD_H33a_SRP100500 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.01563 astrocytoma GWASdb SNP-Phenotype Associations 1.0 0.578475 Perturb_10828_KO_Xbp1_SRP197108 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.0522 SNU520 CCLE Cell Line Gene Expression Profiles 1.0 1.52396 786-0 COSMIC Cell Line Gene Mutation Profiles 1.0 null endometrial cancer GWASdb SNP-Disease Associations 1.0 0.439439 GSE88819_1_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Trigeminal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.51 Perturb_16360_OE_Ppargc1a_SRP278337 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.88559 GSE100316_5_v_2_mtor_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_22_OE_Carhsp1_SRP217699 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.77159 EJM COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE246461,GSE246463_5_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null WWC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67985 TRAPPC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12427 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23483 ZNF708 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4971 Perturb_5980_KD_XRN2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.94945 SLC2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2517 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2993 PMC11750912-12032_2025_2606_MOESM1_ESM.xlsx-AR_vs_AC-Name_AR Rummagene Transcription Factor Associations 2026 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF Rummagene Transcription Factor Associations 2026 1.0 null GSE180200,GSE180201_15_v_9_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE62974_1_v_0_epas1_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of nervous system morphology GWASdb SNP-Phenotype Associations 1.0 0.072908 GSE160373_1_v_7_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null OSTM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21357 GSE200352_5_v_0_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE144443_0_v_1_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null malignant neoplasm of the central nervous system GWASdb SNP-Phenotype Associations 1.0 0.292668 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67937 abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.183192 GSE158853_0_v_1_hmgcs2_mouse RummaGEO Gene Perturbation Signatures -1.0 null astrocytoma GWASdb SNP-Disease Associations 1.0 0.439439 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62968 Posterior nuclear complex of thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.952 MFE-296 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_17444_KO_Trp53_DRP003641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GATA1 ENCODE Transcription Factor Targets 1.0 null SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4737 GSE111660_2_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null TNFRSF18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14957 GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CRBN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40974 Perturb_4535_KO_Mll3/Mll4_SRP064855 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.85853 GATA2 ChEA Transcription Factor Targets 1.0 null ATN-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null nephrolithiasis GWASdb SNP-Phenotype Associations 1.0 0.689964 Perturb_1448_KO_Mir424_SRP312332 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.52251 Nasopharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87376 Perturb_14518_Mut|KD_Kras_SRP200686 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.44126 Perturb_4446_KD_Fbl_DRP007972 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.58539 NB(TU)1-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null UBE2O CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8098 PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_10784_KO_Mlkl_SRP370632 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.01595 GSE203362_0_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_13615_KD_Sfpq_SRP045368 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.73566 CCNB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67065 NCIH1623 CCLE Cell Line Gene Expression Profiles 1.0 1.61369 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23483 PMC10898041-41065_2024_311_MOESM1_ESM.docx-0-FOXL2_FOXL2 Rummagene Transcription Factor Associations 2026 1.0 null ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2871 NCI-H838 COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO-678 COSMIC Cell Line Gene Mutation Profiles 1.0 null HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9226 GSE237040_6_v_5_notch3_mouse RummaGEO Gene Perturbation Signatures 1.0 null MLL1/2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.607 GSE221327_8_v_11_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2993 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31031 non-hodgkin lymphoma GWASdb SNP-Disease Associations 1.0 0.371746 Perturb_8061_KO_ZCCHC4_SRP350212 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.78961 C11orf68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.943 GSE213632_3_v_6_acod1_mouse RummaGEO Gene Perturbation Signatures 1.0 null magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26047 Bronchoalveolar system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE161055,GSE161056_1_v_0_hira_mouse RummaGEO Gene Perturbation Signatures 1.0 null KYSE-450 COSMIC Cell Line Gene Mutation Profiles 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.19454 ANKRD13C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55664 RELB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3289 layer II of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.896497 CLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15946 MCMBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64259 neuroepithelial neoplasm GWASdb SNP-Phenotype Associations 1.0 0.292668 layer I of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.915632 DNER CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91358 Perturb_9718_OE_Wt1_SRP126738 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.40306 CSNK2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12549 LHX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45208 GSE112762,GSE112767_2_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null MFSD6L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05867 CEP41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.75812 GSE153907,GSE153908_0_v_1_azathioprine_human RummaGEO Drug Perturbation Signatures 1.0 null BC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null FUOV1 CCLE Cell Line Gene Expression Profiles 1.0 1.4966 cell type cancer GWASdb SNP-Disease Associations 1.0 0.2799 GSE146156_2_v_3_tagap_mouse RummaGEO Gene Perturbation Signatures -1.0 null tet1_21295276_mesc_v6.5_lof_mouse_gpl6887_gse26900 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.010346 SNU-182 COSMIC Cell Line Gene Mutation Profiles 1.0 null MARK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19005 Perturb_11979_KD_Etv5_SRP304972 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 H290 COSMIC Cell Line Gene Mutation Profiles 1.0 null Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.3462 GSE152937_12_v_1_slc16a13_mouse RummaGEO Gene Perturbation Signatures 1.0 null spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04925 SW837 COSMIC Cell Line Gene Mutation Profiles 1.0 null KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8997 Perturb_3444_KO_Acsl6_SRP321472 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.77053 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23483 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_3202_KO_Trp53_DRP003641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.13419 Perturb_1967_KO_Dgcr8_SRP258731 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.77492 HSD17B10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86083 Perturb_1204_KO_Sp2/Sp1_SRP302435 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.69905 Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ELOF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03639 GSE238116_1_v_0_egr1_human RummaGEO Gene Perturbation Signatures -1.0 null intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29219 bilirubin GAD Gene-Disease Associations 1.0 null external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0289 GSE109565_12_v_11_glyphosate_human RummaGEO Drug Perturbation Signatures 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2993 GSE131377_1_v_0_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null