association dataset threshold value standardized value DCLRE1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82504 MAGEH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94386 GTEX-XMK1-2526-SM-4B666 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04829 U251MG CCLE Cell Line Gene CNV Profiles -1.0 -1.46465 496100377_PCx_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.29171 EEF1AKMT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82605 GSE202434,GSE202438_7_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18984 ZNF726 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86165 centromedian nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14746 GSE190186,GSE190188_8_v_10_apoe_mouse RummaGEO Gene Perturbation Signatures -1.0 null hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25005 496100485_PCx_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.26413 CCDC85C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2567 Autism spectrum disorder GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 UAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62178 KIF21B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45203 GTEX-PX3G-0326-SM-2I3EO GTEx Tissue Sample Gene Expression Profiles 1.0 0.833878 SRD5A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11207 PMC5472759-ncomms15770-s2.xlsx-KIRC_mean_chr8_GISTIC_CN_by_gen-Supplementary_Data_1_TCGA_KIRC_mean_CN_near_MYC_MYC Rummagene Transcription Factor Associations 2026 1.0 null MRGBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17353 Perturb_9893_KD_SSRP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.49452 501A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.892337 TCF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.621 FH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33513 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.74733 PDXK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36826 FCHO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15277 SEMA6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41772 HOXB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32092 ASAH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63517 TLX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4253 striatum_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.867039 POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X8HC-1626-SM-46MWE GTEx Tissue Sample Gene Expression Profiles 1.0 1.39354 TP53INP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50587 SHSY5Y CCLE Cell Line Gene CNV Profiles -1.0 -2.12907 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.29881 MARCHF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1057 GTEX-SUCS-1126-SM-4DM61 GTEx Tissue Sample Gene Expression Profiles 1.0 0.967131 GTEX-U3ZH-0926-SM-4DXU4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.969866 TRNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88178 GTEX-UJMC-0526-SM-3GAE3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10212 LPIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71251 GTEX-TKQ2-1026-SM-33HB7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835134 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23981 GTEX-RWS6-0326-SM-2XCAP GTEx Tissue Sample Gene Expression Profiles 1.0 0.932025 RXRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60832 GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 1.12213 RAB3D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43274 GTEX-REY6-0626-SM-2TF4G GTEx Tissue Sample Gene Expression Profiles 1.0 1.15038 RHBDF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5291 NCIH2073 CCLE Cell Line Gene CNV Profiles 1.0 2.11558 GSE182921_0_v_1_slit2_human RummaGEO Gene Perturbation Signatures 1.0 null IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13464 CLTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65439 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.87846 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.09342 GTEX-REY6-2126-SM-48FD9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.953001 CTCF_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13081 RNF26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24106 SLC39A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90503 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.45101 EXOC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05015 ATOH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.12373 PWWP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7444 HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15844 GRHPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64351 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ATP13A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72391 SLITRK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78026 HIKESHI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31517 496100532_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.50477 NABP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53071 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GNG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03775 SPIN2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18738 GTEX-N7MS-0826-SM-2HML4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.887067 PRAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11753 SLC50A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70242 MRPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40652 TSC22D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70989 INAFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15089 HOXA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40803 Perturb_9968_KD_UPF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.3226 EFR3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93849 TRIM13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57568 NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.476 bed nucleus of stria terminalis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14223 TMED7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98354 GSE97278,GSE97280_2_v_1_nsd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SP140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46128 dorsolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.977688 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 2.09551 TCF21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.81716 KLC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16502 NOS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69046 NANS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84451 MEG-01 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 MPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54159 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.76912 GSE179031_0_v_2_foxp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GPATCH11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86556 GTEX-RTLS-0426-SM-2TF5K GTEx Tissue Sample Gene Expression Profiles 1.0 0.92087 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05915 CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.857509 SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9233 Perturb_14901_KO_H15_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.88045 SMARCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07451 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 2.15624 ITGB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43173 PGR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1084 TAF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6493 NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.29247 CDC42BPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22467 DHRS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.80653 GSE147366_1_v_4_med13_human RummaGEO Gene Perturbation Signatures -1.0 null GSE131798,GSE131804_1_v_0_igf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE215351,GSE215794_4_v_3_kdm8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE127790_4_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZSCAN29 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8022 DNAJC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97685 Zfp809 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.5766 GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.53868 GSE201309_5_v_3_matrine_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_9880_KD_RUNX1_SRP368113 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.61023 496100385_TCx_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.19215 GTEX-X4EP-0726-SM-3P5YJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.16659 AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null A1207 CCLE Cell Line Gene CNV Profiles -1.0 -2.34685 GDF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81594 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.9566 OPM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.43537 496100375_FWM_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.00152 Perturb_9962_KD_GLRX3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.72067 MYOZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59066 motor nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.18801 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42009 ZNF267 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47511 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.944358 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7986 RPL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19015 agranular insular cortex (area Iag) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25497 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.79525 HHIPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85888 TIMP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45018 KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13265 GSE114992,GSE114993_7_v_3_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null TMEM147 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32698 DAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11101 RARA::RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5719 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.43819 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.39462 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0694 GSE190186,GSE190188_8_v_5_apoe_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8820483-Table7.xlsx-HF_vs_LF-mRNA_LTF Rummagene Transcription Factor Associations 2026 1.0 null KCMF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23623 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.892727 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.98036 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SYS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42172 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.826396 CCDC106 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85516 NDUFAB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27963 GTEX-OXRO-0126-SM-2YUN4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.872167 Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 HEB MotifMap Predicted Transcription Factor Targets 1.0 null ADPRM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68432 RET CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61594 TUBA1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96659 GTEX-U3ZG-0326-SM-47JXN GTEx Tissue Sample Gene Expression Profiles 1.0 1.09324 Perturb_9924_KD_RBM22_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.02772 DHCR24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.85564 GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 0.925979 TTL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41177 PIAS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3478 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.944898 Perturb_9992_KD_PABPC1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.23764 Perturb_10030_KD_EIF4G2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.01771 PAX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9346 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.54335 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null TDRD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96176 DRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24981 layer IIIb of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25116 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.66292 TMX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36301 CLK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92089 GTEX-X4EP-0826-SM-3P5YK GTEx Tissue Sample Gene Expression Profiles 1.0 1.32806 CKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39691 KNSTRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87021 SHISAL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57048 CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44875 GTEX-WI4N-1426-SM-3LK7H GTEx Tissue Sample Gene Expression Profiles 1.0 0.960357 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01573 FNBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7689 PITPNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06417 NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5037 H3C4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23516 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0477 orbital frontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02688 GTEX-XYKS-0526-SM-4BRW2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835728 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SOCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13741 KURAMOCHI CCLE Cell Line Gene CNV Profiles 1.0 1.39169 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.37481 PRKCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73376 ATF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.162 hsa-miR-4694-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.58385 H2AC25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72036 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32772 PRSS22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97131 ZSCAN23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28891 HARA CCLE Cell Line Gene CNV Profiles 1.0 1.41839 Perturb_10053_KD_RRP9_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.09581 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.82523 GSE114992,GSE114993_0_v_11_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null TROAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08497 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.937625 ANKRD46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52542 GSE214823,GSE214824_5_v_7_crtc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null LRATD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82559 ASGR2 Pathway Commons Protein-Protein Interactions 1.0 null OVMIU COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 INF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.09865 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02471 NPEPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50886 NAA38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80978 temporal pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.956908 MYL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63909 HOP-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868824 PAX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39549 NDUFB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40595 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893168 HTR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52638 AHCTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66874 NUDHL1 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 AMD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34579 inner CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.871529 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04711 Perturb_10010_KD_UPF2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.92304 COX7A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40733 PRELID3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11171 SERP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74538 CTCF-33576154-HUMAN-LIVER-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null EGFL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18962 ZC3H13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78506 CCND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87272 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.92995 GTEX-XPVG-2026-SM-4B65E GTEx Tissue Sample Gene Expression Profiles 1.0 0.936869 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 2.11215 AMPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42716 SH3GL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12367 NKX2-5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9416 CYP27B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50567 WNK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53765 GTEX-WHSE-3126-SM-3P5ZI GTEx Tissue Sample Gene Expression Profiles 1.0 1.00008 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.08842 LHX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50468 pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.918505 Perturb_9923_KD_PTBP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles 1.0 0.996697 TJP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95041 ZNF692 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96087 GTEX-REY6-0726-SM-2TF4M GTEx Tissue Sample Gene Expression Profiles 1.0 1.36757 TCEAL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51415 EPN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20435 496100401_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.66324 GOLT1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59797 CENPW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82464 CDK5RAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78478 Perturb_10067_KD_EIF3A_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.59936 SMAD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.62336 RNASE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39099 GSE210885_2_v_4_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41931 SLC41A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57976 primary auditory cortex (core)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40708 NB4 CCLE Cell Line Gene CNV Profiles -1.0 -1.56238 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10442 GSE140200_1_v_0_trim59_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_9853_KD_LUC7L2_ERP124746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.61356 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HNRNPLL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21709 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.898204 zona incerta Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.830025 CDK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97479 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MEG01 CCLE Cell Line Gene CNV Profiles 1.0 1.61794 PDZD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27929 PLCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36402 AZI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3671 PCGF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90308 GTEX-RTLS-2426-SM-46MUO GTEx Tissue Sample Gene Expression Profiles 1.0 0.844103 IP6K1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79516 lateral medullary reticular group, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03093 H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PHF20L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40485 ZNF845 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96376 TMEM101 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34565 MEIS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92785 GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.829669 TRIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17568 PRMT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94588 MSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51117 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FGD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80797 HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18616 KRBA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37391 GSE164494_0_v_2_rab22a_mouse RummaGEO Gene Perturbation Signatures -1.0 null ES-WA7 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.968338 MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9143 pontine nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05685 DAZAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63255 CLN8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61648 TADA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62094 TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3791 SKMEL3 CCLE Cell Line Gene CNV Profiles -1.0 -1.83564 HNRNPCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8028 CTCFL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.6594 BAIAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.301 SUGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46343 GTEX-S32W-2326-SM-2XCAW GTEx Tissue Sample Gene Expression Profiles 1.0 1.38439 dorsal lateral geniculate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04663 GTEX-REY6-1426-SM-48FDK GTEx Tissue Sample Gene Expression Profiles 1.0 0.947977 GTEX-X4EP-2926-SM-3P5YQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.993252 496100278_FWM_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.66513 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.945198 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.48014 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35934 GTEX-PWN1-1526-SM-48TDA GTEx Tissue Sample Gene Expression Profiles 1.0 1.42372 UBR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1681 GAK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04835 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.85308 PINX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46738 RABEPK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92837 GTEX-XOTO-0426-SM-4B66A GTEx Tissue Sample Gene Expression Profiles 1.0 1.27849 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.992655 Perturb_10043_KD_EEF2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.57043 FOXP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90057 AKAP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7566 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.90923 GTEX-S32W-0626-SM-2XCBG GTEx Tissue Sample Gene Expression Profiles 1.0 0.979295 motor nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.54868 inner CP in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08883 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null PABPC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71883 SF3B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4498 KURAMOCHI COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 VSX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16148 HCC38 CCLE Cell Line Gene CNV Profiles -1.0 -1.36331 PMC4728380-ncomms10153-s8.xlsx-MYC_binding_intensity_ALL-Unnamed_15_MYC Rummagene Transcription Factor Associations 2026 1.0 null H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.825839 MTREX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1884 GTEX-P44H-0726-SM-48TBT GTEx Tissue Sample Gene Expression Profiles 1.0 1.43799 GTEX-WFON-1226-SM-3TW8F GTEx Tissue Sample Gene Expression Profiles 1.0 0.883571 BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.7028 TAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49558 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVN-2426-SM-2S1Q4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.830935 Perturb_2124_KD_NFKBIA_SRP285793 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.20905 CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.97629 FUT10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70717 GTEX-P44H-0426-SM-2XCEZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.27874 C17orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39327 paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.8786 HCC1419 CCLE Cell Line Gene CNV Profiles 1.0 2.23665 facial motor nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.93479 Perturb_10078_KD_ZC3H8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.84519 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.78455 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.866782 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.0192 BRINP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23236 GTEX-OXRL-0326-SM-2I3F2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.8268 LMAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.57896 SHLD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24847 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null GTSE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.454 AFAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62507 facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.10908 SNU601 CCLE Cell Line Gene CNV Profiles 1.0 1.74582 Armadillo-like helical InterPro Predicted Protein Domain Annotations 1.0 null ITPR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.50531 hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.69076 REPIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09478 CTNNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84713 EXD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43572 PGBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28769 inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01618 BCAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62804 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ATXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30338 GTEX-WEY5-1326-SM-3GILS GTEx Tissue Sample Gene Expression Profiles 1.0 0.963773 MAP4K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85373 NPAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45693 primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.883782 PSMA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55069 GTEX-Q2AH-0526-SM-2I3ED GTEx Tissue Sample Gene Expression Profiles 1.0 1.07645 PMC11442894-41467_2024_52678_MOESM5_ESM.xlsx-all_MSC_vs_iMPC-Unnamed_0_MSC Rummagene Transcription Factor Associations 2026 1.0 null cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09616 Perturb_8781_KO_DNMT3A/DNMT3B_SRP186642 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.17647 SNAPC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16118 LRP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0923 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86488 GSE181959_1_v_2_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null CEP192 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13306 CDK10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03474 GSE189653,GSE203344_2_v_0_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null SPIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72402 ZNF136 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38258 Perturb_9925_KD_RBM34_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.88448 RTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81862 SLC7A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85958 GSE109530,GSE109531_1_v_3_hdac3_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.02668 ANXA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05329 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S32W-1626-SM-4AD6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.10258 ARMCX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78732 ERF::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.2351 GTEX-SE5C-0926-SM-4BRUF GTEx Tissue Sample Gene Expression Profiles 1.0 1.06364 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.9378 RNF207 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09188 PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_A-GeneName_GATA2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T6MN-0426-SM-32PMF GTEx Tissue Sample Gene Expression Profiles 1.0 1.28798 TMEM184A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32508 Perturb_9989_KD_HNRNPA0_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.69258 ARMC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67096 SYDE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02221 PON2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.04144 HNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53777 ACLY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37287 GSE140997_10_v_1_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RNOR-0526-SM-2TF4O GTEx Tissue Sample Gene Expression Profiles 1.0 1.001 body of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00528 PCLAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75791 RANBP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57626 NCAPG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99011 FMNL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1481 C1orf43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69959 GSE112202_5_v_2_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null GLYATL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60813 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.56456 OPM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.4566 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BV-173 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 SLC10A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87988 GMPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85234 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.11241 RPP25L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47478 KIAA1958 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10464 WASHC2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2585 KNS42 CCLE Cell Line Gene CNV Profiles -1.0 -1.39003 GTEX-SIU8-0526-SM-2XCDP GTEx Tissue Sample Gene Expression Profiles 1.0 1.32397 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.916833 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46956 ZNF444 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16484 TIGD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28552 HIF1AN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14777 SPOPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.49971 DENND4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98396 GTEX-XPT6-0326-SM-4B66V GTEx Tissue Sample Gene Expression Profiles 1.0 1.12565 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960343 ARGLU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17048 cochlear nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44783 Perturb_9911_KD_DDX21_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.17384 Perturb_9975_KD_CKAP4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.31177 HSFX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21444 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.41821 GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.25554 GSE159678_6_v_3_chloroquine_human RummaGEO Drug Perturbation Signatures 1.0 null DNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.95115 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1841 RNF38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99297 CSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01652 CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null CLOCK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0595 CNNM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88842 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.347 GSE179031_0_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TTC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6364 TAGLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.64263 HOOK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.67357 NUDT18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79543 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.990259 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles 1.0 1.04584 KAT6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41825 anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.91182 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.89076 AS3MT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76768 RABGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90801 SATB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5345 SPPL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38771 SRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69066 GNAO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42551 GTEX-WI4N-0726-SM-3TW93 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36981 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.03881 GTEX-WEY5-0826-SM-4LMIH GTEx Tissue Sample Gene Expression Profiles 1.0 1.02633 medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06495 TTLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03314 SDHAF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78443 ADD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3249 H3K9me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TBCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20449 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.850978 GTEX-U8XE-0926-SM-3DB8V GTEx Tissue Sample Gene Expression Profiles 1.0 1.35151 FLII CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41768 ZNF707 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.4192 AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893168 NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.932177 EML3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57782 TSPAN14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40616 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.1407 GTEX-T5JW-0326-SM-4DM6J GTEx Tissue Sample Gene Expression Profiles 1.0 0.842108 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30379 ZFP14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.8225 inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.87278 PMAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44006 MRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29177 GTEX-UJMC-1826-SM-3GADT GTEx Tissue Sample Gene Expression Profiles 1.0 1.05262 NKX2-6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12769 HCC1143 CCLE Cell Line Gene CNV Profiles 1.0 1.54906 GTEX-VUSG-2226-SM-4KKZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.04154 ZNF385B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6281 CCDC96 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.26992 SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975414 H3K9me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OCLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68416 NARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60528 GOS3 CCLE Cell Line Gene CNV Profiles -1.0 -1.57642 ZSCAN20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65085 GSE111660_2_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.2644 OVOL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26763 GSE164494_0_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.93477 PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null MXI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -5.24138 Perturb_10060_KD_ADAR_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.9062 BAZ2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16259 GTEX-SSA3-0326-SM-32QPS GTEx Tissue Sample Gene Expression Profiles 1.0 1.16093 CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null Response to antidepressants (symptom improvement) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.552288 CKAP2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28762 EDF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39992 GTEX-RU72-1226-SM-2TF6N GTEx Tissue Sample Gene Expression Profiles 1.0 0.874373 H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TGM2_KD_GSE23702_715_human_NB4 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZNF707 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64174 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11201 DEGS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20948 MTF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.899 GTEX-WYBS-0426-SM-3NM9M GTEx Tissue Sample Gene Expression Profiles 1.0 1.25248 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles 1.0 1.04056 orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.68965 USP17L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78783 IFNAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30471 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null DEDD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66932 POLH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22551 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22558 ZNF585B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69488 IFIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15877 Perturb_14382_KD_PAX8_SRP276625 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.12916 C2orf81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11998 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50735 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.72053 MYF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01681 principal sensory nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0874 GTEX-UPJH-0726-SM-4IHJW GTEx Tissue Sample Gene Expression Profiles 1.0 1.20053 FXYD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39755 PIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40797 GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.398 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null KRT10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99671 Perturb_10034_KD_PUF60_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.04017 POLR2A ENCODE Transcription Factor Targets 1.0 null NCIH929 CCLE Cell Line Gene CNV Profiles -1.0 -1.83522 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SEPTIN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37088 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.67416 KG-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32623 GTEX-S32W-1526-SM-4AD6Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.01363 TRAF3IP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57659 ESR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.2019 PAX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54122 PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4 Rummagene Transcription Factor Associations 2026 1.0 null DCUN1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16985 THAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.6352 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18616 ZNF317 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.5623 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ELOF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03639 C1orf226 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44164 RAVER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07952 lateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17597 posterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22842 LCN12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03545 LZTS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9996 Perturb_9919_KD_MATR3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.13247 TMEM11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61246 abducens nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10235 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.56295 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.65367 hsa-miR-486-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.961803 GSE201735_3_v_1_cdca7_human RummaGEO Gene Perturbation Signatures 1.0 null DNM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44512 PABPC1L2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15876 GPR63 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4672 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ZNF544 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98491 CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868824 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.83359 NOP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43024 TMEM150A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40047 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18616 PSMA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60098 MANEAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95491 olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.843863 GSE160817_7_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null FASTKD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05505 hsa-miR-4472 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 ERO1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35691 PAK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00565 PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null SPATA24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64514 CIAO2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45926 GTEX-TML8-0326-SM-4GICN GTEx Tissue Sample Gene Expression Profiles 1.0 0.882923 STRADB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24711 BAMBI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37152 LRRC34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65158 KCTD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47706 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13191 H3K27me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2A MotifMap Predicted Transcription Factor Targets 1.0 null hippocampus (hippocampal formation)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14946 CEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37686 RPL26L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22777 VRK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5933 PEX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.33031 ANKRD33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60958 SSBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99245 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NDUFB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97147 GSE225218_8_v_3_abcb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.00202 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.54087 HSD11B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.2762 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.962226 ANKIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07576 ST6GAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79533 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NOA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25159 HCST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16578 GTEX-QEG5-0626-SM-2S1PP GTEx Tissue Sample Gene Expression Profiles 1.0 0.892152 BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.5574 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.249 PPP1R3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96708 Perturb_9990_KD_HNRNPAB_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.38436 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null APAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.57162 PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null GATD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62177 MAML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19588 GSE101767_1_v_0_wdr11_mouse RummaGEO Gene Perturbation Signatures 1.0 null ventrolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27892 CTCF_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_17278_KO_Upf2_SRP038144 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 BRWD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26258 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.890561 MARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.95759 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08102 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29709 pituitary GTEx Tissue Gene Expression Profiles 1.0 1.06373 TDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66024 APEH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41587 23132/87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20622 MYADM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61806 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13956 TPBGL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.26607 ADCK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63871 ANKRD24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75204 NUF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43648 PANC-08-13 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 TESMIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.89093 GTEX-RVPU-1526-SM-47JXQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.15432 POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WXYG-0926-SM-3NB2O GTEx Tissue Sample Gene Expression Profiles 1.0 0.856554 GTEX-XUJ4-1626-SM-4BONV GTEx Tissue Sample Gene Expression Profiles 1.0 0.897569 NKIRAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84298 PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB Rummagene Transcription Factor Associations 2026 1.0 null inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19312 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04937 PGM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84771 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918994 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14683 LU-99A COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CSNK1G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72317 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.77673 GTEX-W5WG-1026-SM-4LMIF GTEx Tissue Sample Gene Expression Profiles 1.0 1.18222 GTEX-S33H-1826-SM-4AD65 GTEx Tissue Sample Gene Expression Profiles 1.0 0.936786 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null S100A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37387 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null POU5F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52164 ZR7530 CCLE Cell Line Gene CNV Profiles 1.0 2.83128 MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3545 GRPEL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37587 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23244 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.900088 CDKN2AIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40793 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.961803 GSE123372,GSE123373_1_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE205163,GSE205164_9_v_4_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 2.28402 SKMEL2 CCLE Cell Line Gene CNV Profiles -1.0 -2.04667 ATXN1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82167 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.61072 ZSCAN5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26095 GSE138633_2_v_0_bag3_human RummaGEO Gene Perturbation Signatures 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66431 TBCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15795 dentate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.32827 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF358 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33576 SNAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15502 NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.504 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.51409 DLX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24545 CHSY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61256 GSE200673,GSE200691_1_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCC2935 CCLE Cell Line Gene CNV Profiles -1.0 -1.67767 H3K27me3_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NIFK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12525 GTEX-TML8-1226-SM-32QON GTEx Tissue Sample Gene Expression Profiles 1.0 0.8451 496100386_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.4484 amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.63855 Perturb_9884_KD_DDX47_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.1331 KIF20A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53773 BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.35834 KYSE-510 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893168 ALCAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56592 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66849 NUP43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5868 SDHAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82418 BPGM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62144 GSE114992,GSE114993_9_v_2_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null orbital frontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02133 Perturb_9969_KD_WDR3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.83328 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TASOR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39955 IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6298 GTEX-QESD-0526-SM-2I5G5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21739 Perturb_9909_KD_RBM17_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.4374 Perturb_9991_KD_ILF2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.10231 TE8 CCLE Cell Line Gene CNV Profiles 1.0 1.60061 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.67953 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2127 GTEX-REY6-1026-SM-2TF4Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.14617 NCIH660 CCLE Cell Line Gene CNV Profiles 1.0 1.43684 Perturb_13822_OE_Efgr_SRP302970 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.55727 PHF23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59088 GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles 1.0 1.21409 CREM JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2332 MRPL49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16078 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 2.045 ASCL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49338 GRK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24073 STAT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67922 HAGHL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48327 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27863 CREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6937 FADD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62706 STRIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03989 GTEX-REY6-0926-SM-48FDA GTEx Tissue Sample Gene Expression Profiles 1.0 0.890683 H3-7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36212 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2575 PAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4364 TAC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21137 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.79785 H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PAPOLA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1786 PRIMPOL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07527 CTCF ENCODE Transcription Factor Targets 1.0 null ACP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29079 B3GNT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59135 GTEX-WHPG-1426-SM-3NMBB GTEx Tissue Sample Gene Expression Profiles 1.0 0.941903 ZNF662 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54819 VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.92351 496100462_PCx_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.63936 Perturb_1420_OE_Aatf_SRP257744 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.83921 DCTD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89637 Ascl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.9637 TM9SF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.85477 CAVIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00768 SLC45A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35755 ZFP62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46573 GOT1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77042 Perturb_9891_KD_HSPD1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.45069 FNDC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13707 H2BC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53031 RB1_KD_GSE50532_623_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ZNF804B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01525 PLBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6722 SHPK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59092 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ZNF74 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31935 GTF3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90221 ERAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18819 GTEX-UJHI-1326-SM-4IHJO GTEx Tissue Sample Gene Expression Profiles 1.0 1.35396 TAF5L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03037 UBXN8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23421 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.59249 TMEM132A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01305 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14095 ZNF221 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38987 496100618_PCx_probable Alzheimer's disease_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.01962 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0772 NCI-H460 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.992655 PIAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46308 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.49335 HIBADH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86132 globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21275 ZNF107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27108 primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.963378 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null SLC16A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15572 UBE2L6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69391 ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8101 WDR82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56877 Perturb_16396_KD_Yap1_SRP244345 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.44443 GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles 1.0 1.20754 LHX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61447 Nrf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 51.9899 fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12295 HS-578-T COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 RBM8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82079 ARV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93111 NCI-H1944 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34459 LAMTOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90578 posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.85076 Perturb_9970_KD_WDR43_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.13954 CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.56894 parolfactory gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02144 POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TRIML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40094 corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.32487 TTLL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42308 TRIM26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29411 ZNF274 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2448 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null VPS37D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95311 GTEX-X4EO-0526-SM-3P5Z3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10818 Sporadic Parkinson Disease DisGeNET Gene-Disease Associations 1.0 null cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.07977 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02346 Ebf4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 42.5879 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 2.11929 OXCT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52027 TT2609C02 CCLE Cell Line Gene CNV Profiles -1.0 -1.62826 ZER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41512 nucleus accumbens, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.84569 cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.915998 SLC25A27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90897 MUTYH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57891 RNPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97338 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.13676 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.864126 STX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84735 GTEX-X5EB-2626-SM-4E3HZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.935723 GSE162575,GSE162609_3_v_2_tfe3_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF652 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61918 ANAPC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25691 cuneate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.39094 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.96015 GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10556 CTAGE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34157 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.18813 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null ZNF700 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12127 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41706 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRAPPC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42318 GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles 1.0 1.32486 ZNF875 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08366 Perturb_9885_KD_HNRNPL_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.23743 BEND5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60247 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.97971 PDE5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07916 MANEA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54713 striatum_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31312 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.93763 PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54198 ABHD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44875 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.843753 Perturb_9988_KD_CNOT7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.00999 UBAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75721 GSE127790_13_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05324 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50033 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.880355 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null pretectal nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13383 LSM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15465 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25911 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06383 H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_10052_KD_RPS19_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.73971 FZD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58912 ALDH4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.51346 ADCY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70764 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QEG5-0926-SM-2TC64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22621 RIC8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36205 granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11231 PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null TPRA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81793 GSE127790_10_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45474 WDR48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57291 H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FAM120B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85166 MDAMB436 CCLE Cell Line Gene CNV Profiles 1.0 1.66044 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.30674 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37575 fallopian tube GTEx Tissue Gene Expression Profiles 1.0 0.876908 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50272 H2AB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8037 GPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80735 ABAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96371 496100458_FWM_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.1998 GSE224294_1_v_2_ngly1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE140997_4_v_3_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null ATP5MJ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.289 GTEX-RUSQ-1026-SM-2TF6V GTEx Tissue Sample Gene Expression Profiles 1.0 0.827408 ASCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.66053 496100407_FWM_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.21219 NT5C3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38968 TMEM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2618 CAPN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39215 EME1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06658 Perturb_3586_KD_KHSRP_SRP250831 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.52009 CENPX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29852 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null 496100363_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.46343 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NLE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51904 ATG9A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35346 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.62081 POU2F1-35413990-HUMAN-ARNEGCRPROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null MYO1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96372 MCRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99814 TMEM140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27842 GTEX-OXRO-1726-SM-3LK6C GTEx Tissue Sample Gene Expression Profiles 1.0 1.35168 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83963 Perturb_9882_KD_UTP3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.61603 AK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.956 MPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03693 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.87189 ZNF181 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29746 HS2ST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74733 Perturb_17282_KO_Hsf5_SRP345601 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.969418 CLTC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36805 H2BC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.29002 SEC63 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94623 PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4 Rummagene Transcription Factor Associations 2026 1.0 null H2BC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95119 PTOV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82067 PITPNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07627 LAMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.59931 MAPKAPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.61766 HIVEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93835 SESTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80054 ING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61736 ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3163 HAND2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7432 SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.1032 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE126345_2_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.62817 GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.884373 GTEX-U8T8-1426-SM-3DB9H GTEx Tissue Sample Gene Expression Profiles 1.0 1.12568 PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null Coronary artery calcification GWAS Catalog SNP-Phenotype Associations 1.0 0.048624 VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.877298 TTLL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63108 NEPRO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1491 JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5303 GTEX-NFK9-1026-SM-2HMK1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14427 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13265 SRD5A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02544 GTEX-U412-0326-SM-3DB9L GTEx Tissue Sample Gene Expression Profiles 1.0 1.04534 MT-CO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58026 TMEM143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05978 DBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99375 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0821 496100393_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20148 ventrolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14812 ZNF737 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31602 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.67097 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.859828 NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.27553 ITGA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.12587 TTLL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47942 IRX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15996 SIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40425 D-566MG COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1853 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.904128 BBS10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63317 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.56608 NUMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53373 GTEX-OHPN-0011-R7A-SM-2I5FI GTEx Tissue Sample Gene Expression Profiles 1.0 1.11247 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.15307 CALML6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33064 GTEX-SN8G-0326-SM-32PLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.14793 GTEX-S4Q7-1426-SM-3K2B9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.946686 GTEX-QEG5-0426-SM-2I5GJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.38944 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.835096 GLIS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88137 hsa-miR-3148 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00135 TMC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33441 SP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31449 POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.33506 BHLHA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40454 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42884 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37575 KLHL31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67319 LPXN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04365 HMGB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11614 CLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00458 CCDC92B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50248 ELK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8175 ZNF275 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89632 CEBPD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07274 DDX46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14252 SNU119 CCLE Cell Line Gene CNV Profiles 1.0 2.69473 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65061 HGC27 CCLE Cell Line Gene CNV Profiles -1.0 -1.35886 HSD17B4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56283 GSE188832,GSE188835_0_v_1_irf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNTA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99942 GSE114992,GSE114993_7_v_11_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33037 ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.0726 rostral migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64693 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3436 RPP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24578 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25151 GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.57302 H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBED5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7337 SEMA3F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75669 EBPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14117 C6orf62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61602 CSNK2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.10422 BOLA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48403 UACC893 CCLE Cell Line Gene CNV Profiles 1.0 1.43735 ABLIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01197 primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11926 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null RSBN1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47025 NUP155 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7521 Perturb_16730_KO_Pin1_SRP069191 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.06358 organelle LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-Q2AH-1826-SM-2S1Q2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06786 ARSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0095 TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.188 SERPINF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.33778 CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TXNDC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41144 TIRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6991 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03227 MAPK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4306 SLC39A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92257 ETV2::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.0528 SRP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21263 GSE164494_1_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null NCIH2081 CCLE Cell Line Gene CNV Profiles -1.0 -1.34554 ZNF750_KD_GDS4599_177_human_HaCaT keratinocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-WI4N-0626-SM-3TW8Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.2538 WT1-25993318-PODOCYTE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_10024_KD_SRFBP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.59461 GSE189653,GSE203344_5_v_3_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null KDR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75817 GTEX-RM2N-1126-SM-48FCY GTEx Tissue Sample Gene Expression Profiles 1.0 0.974463 Perturb_14955_OE_PRDM1_SRP287780 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.232 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.0422 blood GTEx Tissue Gene Expression Profiles -1.0 -1.3174 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43378 Perturb_12997_KO_rs2431697_ERP121303 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.6792 Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.4254 SYAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02541 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48088 GSE142684_4_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null TCEAL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58548 ST6GALNAC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01333 LAYN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2792 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17531 CCDC120 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76423 Perturb_10007_KD_HNRNPA1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.49062 LSM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12476 GTF2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68862 IFRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07319 GTEX-OHPN-0011-R2A-SM-2I5FB GTEx Tissue Sample Gene Expression Profiles 1.0 1.01621 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918994 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884167 GTEX-RUSQ-0526-SM-2TF72 GTEx Tissue Sample Gene Expression Profiles 1.0 0.861403 TIMM8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03 SMG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3805 PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RWSA-0926-SM-47JXW GTEx Tissue Sample Gene Expression Profiles 1.0 1.20184 PRSS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34002 H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 2.10112 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.05696 H3K9me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HMOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4093 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32564 PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null ACBD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57513 CPNE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50773 central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.84825 ALX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40756 GTEX-XOT4-0426-SM-4B66T GTEx Tissue Sample Gene Expression Profiles 1.0 1.18008 hsa-miR-607 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.43616 GUF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54725 Perturb_3178_KO_KDM1A2a_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.85715 hsa-miR-4488 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GTEX-OHPN-2726-SM-2I5H4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13843 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RAP1GAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37367 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE202434,GSE202438_4_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.995041 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.80175 GSE142684_4_v_7_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30535 RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6312 CER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04528 GSE189653,GSE203344_4_v_3_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null SULT4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11833 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0726 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13265 TEX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18246 GTF2IRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32551 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84846 NFATC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42591 GTEX-REY6-1126-SM-48FDU GTEx Tissue Sample Gene Expression Profiles 1.0 0.97322 MCTS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49044 GTEX-Q2AI-0826-SM-48TZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.27801 CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.8801 GTEX-N7MS-0426-SM-2YUN6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28236 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PRKDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54676 BRI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44594 ABITRAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36638 GTEX-T5JW-0426-SM-4DM7M GTEx Tissue Sample Gene Expression Profiles 1.0 0.891463 ELAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13599 Perturb_10045_KD_EIF3D_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.87037 MTFR1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40889 GSE114992,GSE114993_0_v_3_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-0326-SM-4DM5C GTEx Tissue Sample Gene Expression Profiles 1.0 0.945328 CCNI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45941 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0694 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12687 Perturb_9929_KD_TARDBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.5229 posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45377 UHMK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.27615 dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49259 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24794 GPX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21014 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24472 UTY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03709 C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.891724 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03237 SACS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94904 UPK3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.313 TMEM191B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16763 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE202434,GSE202438_4_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 0.959331 CD24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7951 GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 0.869673 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06702 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89991 GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles 1.0 0.911009 GTEX-P4PP-1826-SM-2S1NT GTEx Tissue Sample Gene Expression Profiles 1.0 0.830157 GTEX-Q2AG-0526-SM-2S1PW GTEx Tissue Sample Gene Expression Profiles 1.0 0.887794 SRPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43175 PMC5313641-CAM4-6-349-s001.docx-0-HIVEP1_HIVEP1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.991825 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null KG1 CCLE Cell Line Gene CNV Profiles 1.0 1.61766 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H2BC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.55219 PIKFYVE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18713 ZMYM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70065 USP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54086 GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles 1.0 0.94057 GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.16492 primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.940031 CTCF_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SHMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05319 NLRP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97114 GTEX-X4XY-0526-SM-46MW1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03651 FAM50A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84378 RAB2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46453 VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10094 PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.26208 OCIMY5 CCLE Cell Line Gene CNV Profiles 1.0 1.38737 ZNF469 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42334 MT-ND4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28111 NCI-H1781 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 SCGB3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72848 SUPT5H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.1279 head of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02882 GTEX-OHPN-0011-R5A-SM-2I5FF GTEx Tissue Sample Gene Expression Profiles 1.0 1.0911 H9 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.31805 DDX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5935 RCBTB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33828 basolateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.26687 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07927 TMEM87B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43986 SNU1197 CCLE Cell Line Gene CNV Profiles -1.0 -2.59446 SEZ6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19089 Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.6384 Perturb_10035_KD_PUM1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.39311 YBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23273 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27949 GTEX-QXCU-0626-SM-2TC69 GTEx Tissue Sample Gene Expression Profiles 1.0 0.927932 PAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23902 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960343 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.84042 PCSK1N CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92717 Perturb_10036_KD_PUM2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.84953 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.981166 USP27X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62236 PDCD6IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34597 MGST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16171 Perturb_10025_KD_TIAL1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.0516 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54915 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34057 TMEM205 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.98597 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.51131 TCEAL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34982 LBHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90602 TSC22D4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27262 USP22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.64339 FOXO3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16005 GSE131649_2_v_9_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.93739 PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4 Rummagene Transcription Factor Associations 2026 1.0 null CDCA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87035 GTEX-S4Q7-0726-SM-4AD5F GTEx Tissue Sample Gene Expression Profiles 1.0 0.947778 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09504 PTPRZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58808 GALR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00574 POLR1F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3381 GTEX-S341-1126-SM-4AD6T GTEx Tissue Sample Gene Expression Profiles 1.0 1.12404 DYNC2I2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05314 JURLMK1 CCLE Cell Line Gene CNV Profiles 1.0 1.40757 GALNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89371 ZNF347 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78111 HT29 CCLE Cell Line Gene CNV Profiles 1.0 2.11932 primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.922015 PLPP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51489 CYTH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99287 ALDH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85758 ZNF224 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62402 Mafb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0595 GTEX-XPVG-0526-SM-4B65N GTEx Tissue Sample Gene Expression Profiles 1.0 1.02662 STK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80056 H2AZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71811 ZFYVE16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34811 GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.93666 SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02346 RSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90887 C5orf15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47125 lateral medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.987735 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960343 SP110 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37212 ZR-75-30 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null MAT1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71858 FBN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52317 GSE210885_2_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNU216 CCLE Cell Line Gene CNV Profiles 1.0 1.44876 FBXW4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43182 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30329 Perturb_9894_KD_STAU1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.59519 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05401 HCC2157 CCLE Cell Line Gene CNV Profiles 1.0 1.33953 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.84133 CUL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4263 GTEX-X5EB-2326-SM-46MW5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32411 NDRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83183 oculomotor nuclear complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.992639 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USP42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16099 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF718 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30944 Perturb_9959_KD_SUPT6H_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.61959 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15496 NEMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98339 GSE225218_2_v_3_abcb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.943341 GTEX-SIU8-0426-SM-4BRUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.19455 GNPDA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57553 FRAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64051 SYNDIG1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61782 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null EAPP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61087 KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02346 GTEX-PWOO-1226-SM-48TCO GTEx Tissue Sample Gene Expression Profiles 1.0 1.15258 GTEX-RTLS-0826-SM-2TF5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.29457 COL26A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51903 upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.0982 GSE201309_4_v_3_matrine_human RummaGEO Drug Perturbation Signatures 1.0 null PHC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82962 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null WDR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93115 hsa-miR-3688-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 EIF4A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65988 Perturb_10165_KD_DOT1L_SRP292382 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.4413 GTEX-XBED-1626-SM-47JYN GTEx Tissue Sample Gene Expression Profiles 1.0 0.825611 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74775 PPP2CB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5025 RDM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5745 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2473 GTEX-S32W-2426-SM-2XCAT GTEx Tissue Sample Gene Expression Profiles 1.0 1.03147 Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.883813 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4773 PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null SP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1103 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09541 UFD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4363 GTEX-QV31-0626-SM-447C5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.881954 TYW3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89997 H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Erosive tooth wear (severe vs non-severe) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.6 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.883782 PRADC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32698 RNF175 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.25234 GTEX-OHPN-0011-R4A-SM-2I5FD GTEx Tissue Sample Gene Expression Profiles 1.0 0.925152 ARPC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08953 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.53553 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19537 GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles 1.0 1.04179 RFX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6616 GSE114992,GSE114993_7_v_5_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null FYN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25731 mediodorsal nucleus of thalamus_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32888 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14285 VPS52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0079 ARMCX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22124 striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.920381 GTEX-XYKS-2426-SM-4AT43 GTEx Tissue Sample Gene Expression Profiles 1.0 0.978247 GTEX-N7MT-1426-SM-3LK5M GTEx Tissue Sample Gene Expression Profiles 1.0 0.953435 CHCHD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65194 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23894 KDM1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.10054 U343 CCLE Cell Line Gene CNV Profiles -1.0 -2.11 CYP2U1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05524 TFAP4::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.7449 FOSB::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5154 TDRKH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97979 HOXC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5436 GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles 1.0 0.852966 PAX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7295 Perturb_9966_KD_SF3A3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.1623 TRAPPC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43495 GSE164494_1_v_2_rab22a_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF416 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8406 GSE153907,GSE153908_0_v_1_azathioprine_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-U412-0226-SM-3NMC8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10542 B4GALT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70371 GTEX-QEG4-0626-SM-2S1OY GTEx Tissue Sample Gene Expression Profiles 1.0 1.16086 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.67066 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.04758 Perturb_10073_KD_SLBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.38578 SCMH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12993 upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69455 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.87189 SDF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42023 TP73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22411 basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.965161 SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01942 SCAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47518 POLR2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74357 ZNF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.98484 hsa-miR-4447 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 ZNF750_KD_GSE38039_696_human_HaCaT keratinocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_10066_KD_DNAJC21_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.50617 FAM131A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47949 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.74004 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null PLEKHG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45158 ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.593 GTEX-WOFL-0626-SM-3MJG3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45914 DVL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11516 Perturb_13256_KD_Phf5a_SRP083772 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 15.3005 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cuneate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0404 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18616 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83963 layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.908554 GMPPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73792 ZNF584 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42517 MRPS28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30576 HOXB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5948 RDX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56506 VAMP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59693 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.021 SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.832626 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MICAL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.03298 POU2F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88771 EP300_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0526-SM-32PMS GTEx Tissue Sample Gene Expression Profiles 1.0 1.31349 OSR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4415 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2935 Perturb_9993_KD_PPIL4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.46857 HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36324 GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles 1.0 1.44387 transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05475 RPL37A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13134 hsa-miR-4777-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2852 CEP68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78549 TCEA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70216 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.54777 H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.56488 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.804 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05225 AKR1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08115 CNN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34247 GSE180951_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Perturb_9994_KD_RPS3A_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.61671 SNU668 CCLE Cell Line Gene CNV Profiles 1.0 1.4348 KDM1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37442 LRP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97296 WM88 CCLE Cell Line Gene CNV Profiles -1.0 -1.59717 GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles 1.0 0.947788 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.02068 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.907756 LU99 CCLE Cell Line Gene CNV Profiles 1.0 1.35809 KHDRBS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41066 CHK1_KD_GSE54267_671_human_U2OS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null LRCH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64206 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14473 ENDOU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82452 PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null CLASRP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93361 ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.6323 NUDCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.10865 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.842428 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05806 MAP1LC3B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07997 PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null ZNF28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37156 Perturb_9920_KD_NELFE_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.2629 GSE189653,GSE203344_2_v_1_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null GTEX-OXRO-1926-SM-2S1O3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.47653 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.968988 GSE201042_2_v_4_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null OVOL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42741 CIDEA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73519 MICALL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59955 M07E CCLE Cell Line Gene CNV Profiles 1.0 1.3378 H3C7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19464 FDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98708 Perturb_10400_KD_ASH2L_SRP277215 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.42382 TNKS1BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67954 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.0192 SNX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53012 MCM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49789 GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.879774 GABRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88644 MAP3K7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05967 GTEX-XUZC-0926-SM-4BOQF GTEx Tissue Sample Gene Expression Profiles 1.0 0.881577 POLR2F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98278 GLS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90483 GSE144231_4_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9498 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null ZNF175 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8896 MARK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88695 SCC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.87059 KDM2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91767 C10orf82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82599 CSTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.42776 PFKFB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43935 Perturb_10069_KD_ILF3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.03875 MCUR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75065 PDLIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83479 GSE195663_7_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null septal nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.926596 GTEX-S7PM-0526-SM-3NM92 GTEx Tissue Sample Gene Expression Profiles 1.0 0.999911 PRKRIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9559 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39475 INSM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.25 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_10029_KD_CELF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.43442 EID3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75619 LBR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56337 SPTSSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3408 SCN1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1155 ATF7IP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.03589 CIDEC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46264 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04085 GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.76143 GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.19139 cerebellar cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.830549 THAP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69237 PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.81814 GSE141726,GSE141733_1_v_0_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null arcuate nucleus of medulla, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.901686 GTEX-OXRO-0226-SM-3LK6F GTEx Tissue Sample Gene Expression Profiles 1.0 1.39755 CL14 CCLE Cell Line Gene CNV Profiles -1.0 -1.47193 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 2.49842 TRIM41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89181 Perturb_10065_KD_DNAJC2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.45626 GSE210655_3_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Perturb_9964_KD_NSUN2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.2016 DLC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86544 primary motor cortex (area M1, area 4)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02432 CTCF_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles 1.0 0.870491 internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3362 GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 1.3607 KMT2E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96052 RNF181 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36481 PYCR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65169 MAMLD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15221 PEX13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53746 Perturb_17545_KD_EFB1_SRP357509 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.40398 SLC39A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42142 Perturb_16735_KO_Il2ra_SRP167045 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.89099 TRIL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02684 GSE127790_5_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_11732_KO_KDM5A_SRP292672 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.16476 AMOT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68714 nucleus accumbens, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02585 LPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22542 PTPN11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14374 NCIH1781 CCLE Cell Line Gene CNV Profiles 1.0 1.87895 FBXW2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56055 SDHD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62385 ZNF341 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1959 GTEX-OHPN-2826-SM-3LK67 GTEx Tissue Sample Gene Expression Profiles 1.0 0.87262 496100321_HIP_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.72984 SLC52A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15578 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.81649 CGB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2514 Perturb_10062_KD_CPSF7_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.05164 RHOBTB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72479 FKBP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02496 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null 2313287 CCLE Cell Line Gene CNV Profiles 1.0 1.49153 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02967 HARBI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55987 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.68894 NT5C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09917 COV318 CCLE Cell Line Gene CNV Profiles -1.0 -1.76731 H3K27me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GCLM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.49046 PITX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66928 SHROOM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80344 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.919571 ACSBG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79752 LYNX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24591 orbital frontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.82587 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.64627 PPIL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59522 TMEM265 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64744 NCI-H2110 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67934 GTEX-OXRP-2426-SM-2S1NR GTEx Tissue Sample Gene Expression Profiles 1.0 1.08528 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3809 GTEX-SIU8-0826-SM-2XCDQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.837686 ADCY9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51073 GLB1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00366 primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.832749 ARID4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81512 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.66302 CFAP68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57331 GTEX-QV31-1326-SM-2S1QE GTEx Tissue Sample Gene Expression Profiles 1.0 0.862931 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.906074 DNAJA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.37701 subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08747 DB CCLE Cell Line Gene CNV Profiles -1.0 -1.41211 CPEB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32933 NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2935 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 1.92255 TRAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81448 RAF1_overexpression_220_GSE42964 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.84296 496100368_PCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.99475 CCDC113 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50246 LAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.685 SNU-423 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918994 dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33286 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.72868 EIF5A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90811 NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918994 GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.96615 SIAH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6092 PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null MOB3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56753 B3GNT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79999 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.86266 BLZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5888 ZNF684 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.9687 BV173 CCLE Cell Line Gene CNV Profiles 1.0 1.89086 NIPBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70421 NUDT19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20843 SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918994 PARD6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76956 Perturb_9963_KD_MTPAP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.68665 NAALADL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47151 BOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84631 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.963938 C4orf3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.61582 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04236 RNF126 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11025 RNFT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12595 ADH5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.20343 JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.62543 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.74653 GTEX-RU72-0226-SM-46MUD GTEx Tissue Sample Gene Expression Profiles 1.0 0.996362 GTEX-WZTO-0826-SM-3NM8Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.0109 rostral presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39033 cell part LOCATE Predicted Protein Localization Annotations 1.0 null QPRT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24094 PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR Rummagene Transcription Factor Associations 2026 1.0 null SIRT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30091 GTEX-QEL4-0926-SM-3GAD1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.907304 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8885 GSE202434,GSE202438_12_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null G0S2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30907 GTEX-XLM4-0426-SM-4AT54 GTEx Tissue Sample Gene Expression Profiles 1.0 1.4167 GTEX-OHPK-0326-SM-2HMJO GTEx Tissue Sample Gene Expression Profiles 1.0 1.09078 Perturb_10064_KD_DHX30_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.7191 CLN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.20315 DPH7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44535 SCARB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99134 ATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9545 ANAPC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57606 NEUROG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44755 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20585 TNNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13726 CGREF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92742 Erosive tooth wear (severe vs none or mild) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.530103 molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23341 H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SUSD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95858 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.85023 H3K27me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPN-2926-SM-3LK65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1627 Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.0312 GSE119345_2_v_3_bexarotene_human RummaGEO Drug Perturbation Signatures -1.0 null IL17RB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62731 DPPA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54405 FBLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5269 ATRIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58331 CRACR2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02303 TXNL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24028 CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9946 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23734 Perturb_10075_KD_AQR_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 HDGFL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24286 TMEM187 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8381 RTN4R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55911 SLU7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10788 PIGW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83176 piriform cortex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.955516 GTEX-T5JC-0626-SM-3NMA6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21651 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.58423 GCM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1861 GTEX-OOBJ-0326-SM-33HBO GTEx Tissue Sample Gene Expression Profiles 1.0 1.16777 liver GTEx Tissue Gene Expression Profiles -1.0 -0.967985 Armadillo-type fold InterPro Predicted Protein Domain Annotations 1.0 null RPS6KA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41856 PRX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45763 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918994 NDUFA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.85871 VPS26A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44943 CTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74448 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.45838 TMEM109 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36798 EAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4327 CAMSAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07204 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.51108 GSE210885_0_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KYAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96098 RFXAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47476 CCNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.74025 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41853 Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.579 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21065 Perturb_10039_KD_UBE2L3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.83564 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.942003 GTEX-P4PP-1626-SM-2HMJF GTEx Tissue Sample Gene Expression Profiles 1.0 1.21302 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PRICKLE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45007 OST4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42239 ELP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69778 HCC1428 CCLE Cell Line Gene CNV Profiles 1.0 1.83505 H3K27me3_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMEM89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94709 GTEX-XOT4-0526-SM-4B66O GTEx Tissue Sample Gene Expression Profiles 1.0 1.20302 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11156 DNMBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55665 NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4937 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.80175 SLC7A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38527 SEC24A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87207