association	dataset	threshold value	standardized value
thoracic outlet syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00414
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85044233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06004
Perturb_11231_KO_Il4_SRP100781	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.82269
DCP1A	ChEA Transcription Factor Targets	1.0	null
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM209	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16101
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12384
BRD-K97298761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12179
RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K37392901_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251293
hsa-miR-4676-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.269
NCIH520	CCLE Cell Line Gene Expression Profiles	1.0	1.34769
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.934315
Perturb_10241_KO_Crat_SRP394715	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.93158
PMC12356310-mmc1.xlsx-Rep_3_Control_and_MTR4_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SNB75	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.53553
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31518
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
SA-32-CC58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268177
BRD-K73296134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94569
NFIC	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2763-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0778
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0844
Liver hepatocellular carcinoma_LIHC_TCGA-T1-A6J8-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8101445-mbc-32-475-s003.xlsx-HEK_Tim29_KD-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38350115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02761
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46902
CREB1	ENCODE Transcription Factor Targets	1.0	null
BRD-K34489843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1788
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74537
hsa-miR-4433	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
DB-73-BC12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320954
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50814
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.601
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36558
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DACH1-20351289-CHIP-SEQ-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77128
SLC25A3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17988
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33633
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00579
GSE203267_0_v_1_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
DB-34-QA60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325629
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.995732
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Setleis syndrome_Skin fibroblast_GSE16524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.789689
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22262
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.26359
vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.68148
GA-59-RW04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232337
ES2	CCLE Cell Line Gene CNV Profiles	1.0	1.38988
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24362
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52083268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13508
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DETROIT562	CCLE Cell Line Gene Expression Profiles	1.0	2.37461
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
translation	GO Biological Process Annotations 2023	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-568	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02173
ChIP_TIP60_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DDX17	Pathway Commons Protein-Protein Interactions	1.0	null
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899426
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
BRD-K73355908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07899
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73110675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01917
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201042_6_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28918
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.93452
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7885-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05364
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
phi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AC-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.889486
organellar large ribosomal subunit	GO Cellular Component Annotations 2015	1.0	null
BL5196 (CEP72)	NURSA Protein Complexes	1.0	null
UQCRC2	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5734
H3K36me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88715
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08217
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12260418-pnas.2425984122.sd02.xlsx-TEAD1_6fraction_test_result-Unnamed_3_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_409_KO_IRE1_SRP353826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.01024
pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0221
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913255
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PR8(H1N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.08304
hsa-miR-4690-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K36me3_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL32	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4718	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051939
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
urea cycle disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.438282
BA-19-VU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203299
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74803017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01606
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13068
HNRNPL	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP5L	Pathway Commons Protein-Protein Interactions	1.0	null
PADI4	ChEA Transcription Factor Targets	1.0	null
RHEBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00454887
WEE1_druginhibition_307_GSE38972	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.2159
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3731
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73387
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.439123
BRD-K27902176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60779
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75791
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.88974
ETS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00589413
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EO-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estradiol_homo sapiens_gpl96_gse1045	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RB_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-PC-A5DK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1245b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391176
BCL3	ChEA Transcription Factor Targets	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21005
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.857484
BRD-K70695911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55733
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9739
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.50398
t47d	HPA Cell Line Gene Expression Profiles	1.0	2.31505
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03363
GFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96137
HuO9	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.40636
BRD-K07303502_Arachidonyl trifluoro-methyl ketone_VCAP_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
BRD-K16911140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59193
EC-82-LV30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.453081
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45626
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37109
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838162
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.29873
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83542
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_1_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
SRF_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042933
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3189-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
AP-1 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.026
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.88668
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15611
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825471
rectal cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K79329532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17133
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64682
5878_NUF2_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.25541
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.996305
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15378
MRPL37	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_2303_KD_BRCA2_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.61698
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93601
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21579
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203872
long bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648938
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044814
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33986892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01114
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48475
FABP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00592869
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.77394
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.405197
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rhinovirus infection_Nose_GSE11348	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.42646
Prostate adenocarcinoma_PRAD_TCGA-M7-A725-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17598
GB1_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.20948
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96907
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.87976
TMEM52B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579322
BRD-K33956641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39774
biological_process	GO Biological Process Annotations 2015	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.79714
primary auditory cortex (core)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29461
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE179002_3_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23156
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.496725
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.859044
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TRPT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595323
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08645
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35412
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16971
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3863
mitochondrial translation	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4ND-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GM1600	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.21057
BRD-K36778976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37154
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890233
BRD-K99387963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13756
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05
Perturb_9672_Mut_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.7586
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36928
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25686
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75594
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81219
GTEX-WHWD-2426-SM-3LK6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35562
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985023
hsa-miR-4731-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Lung squamous cell carcinoma_LUSC_TCGA-66-2757-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
respiratory chain	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.423174
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U937_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.40441
GSE196407_1_v_0_fluorouracil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-93-3p	MiRTarBase microRNA Targets	1.0	null
Adenoma_Adrenal gland_GSE8514	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.2568
BRD-K32595757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69029
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CV-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.871479
mitochondrion	LOCATE Curated Protein Localization Annotations	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.80125
BRD-K09993756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08646
Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44667
Perturb_3884_KD_CTR_SRP124930	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.1487
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.34776
JUND	ENCODE Transcription Factor Targets	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.22599
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838162
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835532
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114626
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044883
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943833
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BT-549	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20941
DAP3	Pathway Commons Protein-Protein Interactions	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04997
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	2.25137
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67662
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44158
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MTG1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.62256
FASTKD1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_3H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30261
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11925125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80235
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.881037
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0024
NDUFA9	Pathway Commons Protein-Protein Interactions	1.0	null
Spinal Cord Injury_CNS - Spinal Cord (MMHCC)_GSE16710	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.39319
PARS2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093985
AA-32-DP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264912
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956723
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4730-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPC	Pathway Commons Protein-Protein Interactions	1.0	null
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.516
IGF2BP2	Pathway Commons Protein-Protein Interactions	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.88369
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP5B	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2766-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08534346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40506
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05955
NB7	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.98159
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mammary Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.11945
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JE-22-JR20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24449
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6416_KO_TP53_SRP274402	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.27565
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0125
KE-37	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50114
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75606012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05756
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20064
Lung adenocarcinoma_LUAD_TCGA-67-3772-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21809
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.06881
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06766
Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.847351
BA-39-OX47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23303
BRD-K77445233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25768
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7
NELFE	ENCODE Transcription Factor Targets	1.0	null
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parahippocampal gyrus, right, bank of the cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.913754
BRD-K60068268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13872
BRD-K13970506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17891
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1804
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X2-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.40677
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.950947
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049713
TAF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90480740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23688
yolk sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.40328
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K20420220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50001
inner CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922015
BE-31-XV38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213362
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44625
BF-29-LU75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217328
PMC4090731-bjc2014262x1.xls-Sheet1-CaSig-HSF1_Positive_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2112
SC-72-YW56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.470181
BRD-K30615964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15973
BRD-K36422663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9098
BRD-K73775927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19879
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K36815183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50198
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.818
XC-88-ZM66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24929
YD38	CCLE Cell Line Gene CNV Profiles	1.0	1.33958
CTCF	ENCODE Transcription Factor Targets	1.0	null
DBT	Pathway Commons Protein-Protein Interactions	1.0	null
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.870396
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1945
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929714
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.160254
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436958
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12681960-MCO2-6-e70522-s001.docx-26-EBF3_EBF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
integrin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.077788
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73056
BRD-K42084582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57883
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53_DEPLETION_GDS4070_451_human_MDA-MB-231 breast cancer cells (depleted of MUTANT-p53)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17267
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21659
GTPBP10	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.906798
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64449
E2F6	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-491-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55043
Perturb_4714_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_6412_KO_TP53_SRP274402	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.76912
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03331
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22798
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43564
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14144
6283_PHF19_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.597713
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
MA-88-CA03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237115
hsa-miR-566	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19333
sirolimus_mus musculus_gpl1261_gse21755	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.76523
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1814
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862783
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21534
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.762488
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.932468
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.50987
retrotransposon nucleocapsid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.209513
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80161
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16186
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35324
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26132
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64627
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6911
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.937347
RALY	Pathway Commons Protein-Protein Interactions	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.816068
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6158-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2335_KD_SON_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.21051
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41661
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36891
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60375
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836042
PMC12405659-CTM2-15-e70437-s001.xlsx-Supplementary_Table_5-BioGrid-interaction_protein_with_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10151
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39209
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86651
BRD-K68383485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04436
Ribosomal subunit	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K09454191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.553
BC-61-ZY95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203128
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36657
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4809
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15259307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63786
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.108927
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50273
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15513
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22364
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333341
BRD-K55453160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35796
Perturb_8893_OE_YAP1_SRP151027	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.6198
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21447
bronchiolitis obliterans	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.484364
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MM-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26435104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24511
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPUSD4	Pathway Commons Protein-Protein Interactions	1.0	null
CANX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533608
MALSU1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22615
CFTR_Deficiency_GDS1843_192_mouse_Lungs - Animals examined at 6 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
TIMM21	Pathway Commons Protein-Protein Interactions	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933253
TE4	CCLE Cell Line Gene CNV Profiles	1.0	2.98254
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85892
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U3-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRF1	Pathway Commons Protein-Protein Interactions	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03909
MEF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60218
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K72298899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02054
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.834301
estradiol_homo sapiens_gpl96_gds2324	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76889263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08398
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17851
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05579
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043426
hsa-miR-640	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17705
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11714
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.848686
BRD-A34842997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5055
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.54883
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981729
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23473
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37036
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46529
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14235
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8377
BRD-K11893906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47082
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
superior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10566
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOXP2_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12073_KD_Tgfb1_SRP067296	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.11925
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20600965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07346
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61078510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05955
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78638
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.6464
NR2F2	ENCODE Transcription Factor Targets	1.0	null
ADCK3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K53257131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33402
BRD-K97700172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29481
GTEx Skin 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-5.45754
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49638
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871504
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4742-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
craniofacial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.170498
femur	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.597263
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYCN	ChEA Transcription Factor Targets	1.0	null
HOP-92	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.8607
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12988
PMC3076323-pone.0018064.s016.xls-MYCN_targets_Marson_GSE6007-Unnamed_1_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11140_KO_Myc/Mlxipl_SRP148418	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.51785
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05554
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13346
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16488
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055868
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17648
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64942
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KE37	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59316
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
VA-06-DB75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.779036
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3555
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26231
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37593
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040673
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21535
SFXN1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.065088
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_8870_KD_PNN_SRP063860	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.85193
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04438
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3539
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.51497
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUPV3L1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828351
Perturb_10130_KD_GATA1_SRP090317	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.36961
MRPL23	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7286-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89464
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39897
SARS2	Pathway Commons Protein-Protein Interactions	1.0	null
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043072
RBBP5	ENCODE Transcription Factor Targets	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149760_0_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69264
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04587
Perturb_9667_KO_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.82096
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.02921
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04328
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303345
BRD-K24393110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06845
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15056
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40242
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ribosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SQ1	CCLE Cell Line Gene Expression Profiles	1.0	1.66142
EE-08-SZ54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239442
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostatic Neoplasms	CTD Gene-Disease Associations	1.0	1.35271
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986982
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.921054
REST	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04292
PNPT1	Pathway Commons Protein-Protein Interactions	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.80824
Arteriosclerosis	CTD Gene-Disease Associations	1.0	1.21108
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC0813	CCLE Cell Line Gene Expression Profiles	1.0	1.61912
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE133683_1_v_5_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5280_KO_Ddx6_SRP137728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.80332
DMS273_LUNG	CCLE Cell Line Proteomics	1.0	2.82801
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23711
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056195
Mitochondrial intermembrane space protein transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.393
Lung adenocarcinoma_LUAD_TCGA-38-4628-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22919
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28227
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8429
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865644
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12237_KO_ZMYND8_SRP130942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.11711
POU5F1	ChEA Transcription Factor Targets	1.0	null
hsa-miR-362-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22815
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968388
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K66416915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26054
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.383895
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-33a	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.824295
BRD-K67211407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75581
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24415
ERAL1	Pathway Commons Protein-Protein Interactions	1.0	null
cyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310783
BRD-K35828963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78278
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1-19587682-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.14575
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44926
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08178
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytochrome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.128366
CREB1-15753290-HEK293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Organellar ribosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882749
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.55779
CD24_Reduced expression_GDS1392_93_human_Bone Marrow	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.826814
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.736343
Mitochondrial inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BCL3	ENCODE Transcription Factor Targets	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STAMBPL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00456876
Perturb_7257_KO_LARP1/LARP1B_SRP201361	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.40515
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DCP1A-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.641996
SNU1196	CCLE Cell Line Gene Expression Profiles	1.0	2.03385
PCCB	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K90697692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11818
GSE230174_0_v_1_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
39S ribosomal subunit, mitochondrial	CORUM Protein Complexes	1.0	null
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32268
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14050_OE_NFIB_SRP281947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.10498
centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.246046
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL2222 (COL4A3BP)	NURSA Protein Complexes	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.883
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7734_SEC13_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.04339
mitochondrial translational termination	GO Biological Process Annotations 2015	1.0	null
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21385
ACOT9	Pathway Commons Protein-Protein Interactions	1.0	null
SMAD3-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.212313
AC-43-ZC52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.457401
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35716
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49491
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59185
CHD1-19587682-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8105-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.01072
BRD-K77173942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00261
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20617
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8894
OCIAML5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86936
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acetylcholine-gated channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
BRD-K27035180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26563
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33914
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9422
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09413
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.935543
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14338
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15118
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organellar ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.481
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.1198
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFA13	Pathway Commons Protein-Protein Interactions	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0163
BRD-K60057192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07841
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74831
DLX5_KO_GSE22381_5_mouse_ear (otic vesicle)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K18978916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42875
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81698
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26192
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48013
Ezh2_deficiency_GDS2717_141_mouse_lymph node T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05019
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CNOT3-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCT116_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.85909
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.02972
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.83981
BRD-K73637411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29001
MYC_Activation - 4 hours_GDS2025_724_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0728
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS28	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K53816426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02064
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14066
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95322
NarGHI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
Lung Diseases	CTD Gene-Disease Associations	1.0	1.10527
CRCGN014_HEPG2_3H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52697
pioglitazone_rattus norvegicus_gpl341_gse21329	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Perturb_6381_KD_POU2AF1_SRP336261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.6458
BRD-K77041516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02792
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969119
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_693_KD_SREBP1_SRP064735	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.0336
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61033092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30135
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19158
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.574416
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967191
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40218
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ASXL1	ChEA Transcription Factor Targets	1.0	null
inner CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05441
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863231
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08853
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937603
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0778
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.29371
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2063
hsa-miR-590-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261234
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.17687
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24967
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1547
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33419
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04577
PMC8384902-mmc2.xlsx-4_NEUROD1_high_subtype-Gene_Symbol_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-599	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-590-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PB-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.905
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.956866
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05396
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24549321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07664
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17120673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57443
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89839
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.986445
HCV JFH-1_48Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.94247
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882723
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.14415
H3K36me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284215
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NIPSNAP1	Pathway Commons Protein-Protein Interactions	1.0	null
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988505
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VL-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61274359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52533
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD4_druginhibition_224_GSE50865	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.12913
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.95917
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16093370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27598
rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.141213
Perturb_11704_KD_MIR31HG_SRP051359	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.28926
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09146
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.43477
PMC8566473-41467_2021_26653_MOESM3_ESM.xlsx-SOX2_interacting_proteins-Gene_symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50116
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45922
TEFM	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
MRPL2	Pathway Commons Protein-Protein Interactions	1.0	null
SNU283	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02807
H3K36me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.663657
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mitochondrial translation initiation	Reactome Pathways 2024	1.0	null
CJM	CCLE Cell Line Gene Expression Profiles	1.0	1.38639
C32	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59818
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
BRD-K50234570_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
176_AFG3L2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.557393
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46588
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886052
FOXP2	ENCODE Transcription Factor Targets	1.0	null
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4001
2-iodomelatonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21468
SART1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049019
MRPS5	Pathway Commons Protein-Protein Interactions	1.0	null
SUPT7L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497096
Perturb_600_KO_Runx1_SRP267560	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.88295
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44743425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43343
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30991
Uterine Neoplasms	CTD Gene-Disease Associations	1.0	1.01663
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80221
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sebaceous gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.818
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23993
COLO680N	CCLE Cell Line Gene Expression Profiles	1.0	1.39101
XE-29-LT20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260015
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097437
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62696
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4501-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.506329
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
CB-87-RB49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.598947
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55933
DLD	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE94011_0_v_1_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ITGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09544
SUPT20H_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-8.14508
BRD-K64553072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3853
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43042
laminin-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.249302
arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.996127
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73938
BRD-K92008394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35482
Gastrointestinal cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
forearm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312232
RB1_KD_GSE50532_624_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.913177
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26533
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.830346
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99616396_S1032_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912291
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LOUCY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58845
SMARCA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00534078
TP63	ChEA Transcription Factor Targets	1.0	null
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56303
Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04696
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.33791
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872912
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44733
BRD-K79908599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13114
MAX	ENCODE Transcription Factor Targets	1.0	null
BRD-K91399333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62357
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4663	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SW1271_LUNG	CCLE Cell Line Proteomics	1.0	3.01822
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.31897
Ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.673
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Root resorption	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38332
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264413
neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.079723
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K07501194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24794
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28325
GFAP_OE_GDS1488_254_mouse_Olfactory bulb of 23 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HS281T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84681
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0666
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19612
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28875
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903361
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13987
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23641
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17743125_belinostat_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
macromolecular complex disassembly	GO Biological Process Annotations 2015	1.0	null
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
697	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72389
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.952151
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25109
H3K36me3_splenic B cell_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46065636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2603
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.936055
Pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5606
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41875
Syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.601
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52816
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17445
hsa-miR-361-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14681
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
CAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09361
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.27233
RASSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14716
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
icSARS-Cov_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.85175
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06805
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K10781609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61257
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06665
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DDX5	Pathway Commons Protein-Protein Interactions	1.0	null
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4753
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.33913
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16462
Perturb_11010_KO_Pfkfb4_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57469
BRD-K13389917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35123
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.56269
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LD-47-RN92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310357
CLCN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26035
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATM_knockdown_18_GDS1852	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.67025
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61683
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6365
SMAD3-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56754
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4786-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL50	Pathway Commons Protein-Protein Interactions	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
natural killer cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.830391
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11725
KLF4	ChEA Transcription Factor Targets	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270256
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9253
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-1526-SM-4BOOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988939
SARS-BatSRBD_Day7_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.91001
BRD-K43872193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23541
Perturb_15659_OE_Creld2_SRP373942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.81568
BRD-K25280080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77198
mitochondrial matrix	GO Cellular Component Annotations 2025	1.0	null
HS751T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71609
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.876416
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.95102
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0055
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3170	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76500652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69088
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00911
AA-62-HP31_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206168
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07211
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A9QC-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22915
BRD-K95852319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00788
Colorectal adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73Q-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Large ribosomal subunit	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26233
IB-33-TE51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229897
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.66207
H3K36me3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35458
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Serous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1964
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19822
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261624
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38763
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.21662
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.21855
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24674
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23744
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.38111
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22561
Dermatomyositis_Muscle - Striated (Skeletal) (MMHCC)_GSE1551	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.46992
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24565
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.89922
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950702
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.23424
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55981
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.625056
BRD-K13681383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00552
lateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.898251
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33845
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59736
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38332
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69869
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K28184331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32624
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54448
PPP6R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30379
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054149
BRD-K07420629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17034
Perturb_2829_OE_IGF1R_SRP064353	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.0544
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927572
translation	GO Biological Process Annotations 2015	1.0	null
BC-11-LL59_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280721
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14914
PPARG-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046176
CHAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00424
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SERPINH1	Pathway Commons Protein-Protein Interactions	1.0	null
esr2_15280152_c57bl6_mice_soleus_skeletal_muscle_lof_mouse_gpl81_gds791	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.069441
H3K4me1_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180789_1_v_0_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_8_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K22065327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11733
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36271
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04303
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4136
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11005
BRD-K55452151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1384
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24659381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3067
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.867417
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4719_KO_Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GR-ST	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.31075
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19913
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.19477
Organellar large ribosomal subunit	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51328
BRD-K89179622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02771
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07389
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.30433
GSE205550,GSE205552_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Carcinoma, Hepatocellular_Hepatic Tissue_GSE4612	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.44912
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
polytene chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.345314
BRD-K25064302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41685
TCF7L1_01_346	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62007
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FOSL1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82793574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14606
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42402
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37763
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U937	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48282
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064142
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39017
FARS2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938165
Perturb_4616_KD_Rfx1_SRP231452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.53303
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63908
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.23462
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43159
Inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.08762
agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.852402
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.818
secretory diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.400453
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63655
BRD-K48519079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53402
TMEM45A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531025
BRD-K08308527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45073
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.463149
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849023
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54576503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72613
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HA-22-CY42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392882
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507739
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1172
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971836
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GADD45GIP1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC2965092-pone.0013658.s001.xls-Liangos_SOM_Table1-GeneName_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4667-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3717
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04992384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25955
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8875
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3910	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922327
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HUWE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560492
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCAS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00460899
BRD-K03713632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60422
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945298
nuclear chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.161275
PL-21	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.96826
PMC8045172-13018_2021_2402_MOESM1_ESM.txt--AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37906141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30789
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11276
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45628030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22477
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28338
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15611
MRPL46	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27603
BRD-K24838542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21243
trans-Golgi network transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
Sarcoma_SARC_TCGA-DX-A7EL-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_694_KD_SREBP2_SRP064735	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.2147
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10830421-41589_2023_1452_MOESM5_ESM.xlsx-HEK293T_MAX-Tg_tissues-Unnamed_0_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K24557107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39165
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.14785
BRD-K96069147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39649
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39999
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.200982
BRD-K39600742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32413
Bronchioalveolar carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.32035
Autoimmune interstitial lung, joint, and kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
1-alkyl-2-acetylglycerophosphocholine esterase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10349
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.091
BB-77-QQ71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212298
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCMV_24Hour-Infection+PP2_21084488_GSE24238	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.79945
BRD-K32856496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07031
personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.694301
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPT2	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung Injury	CTD Gene-Disease Associations	1.0	1.02708
ILF2	Pathway Commons Protein-Protein Interactions	1.0	null
EOL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4651
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31868
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.301
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889955
GTEX-NFK9-1226-SM-3LK79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06316
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28518
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81728
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC25A18	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K52075715_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K09487932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70847
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.924103
MIB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K95014129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72382
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RUNX1	ChEA Transcription Factor Targets	1.0	null
Perturb_11016_KO_Ppdpf_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.99265
KDM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0164
PRDX5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23235
adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054834
Prostate adenocarcinoma_PRAD_TCGA-YL-A8S9-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.24598
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62025
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36894
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8143-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.29873
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mitochondrial translation	GO Biological Process Annotations 2023	1.0	null
AE-14-NN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.313176
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45776
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4177
FOSL2	ENCODE Transcription Factor Targets	1.0	null
SREBP2-21459322-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-532-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K56650430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.8719
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874266
Perturb_15624_KO_Il17ra_SRP322111	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.33687
PADI4-21655091-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IPO13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41605
Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216757_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM6A-18722178-U937-AND-SAOS2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95857
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K10761381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07755
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79644
C1QBP	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K38692266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61095
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258852
BRD-K75648723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19695
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.908579
seminal vesicle	HPA Tissue Protein Expression Profiles	1.0	0.88974
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9308
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03852663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30058
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85917
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.212945
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252191
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971836
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.6896
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13961
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05393
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042338
hsa-miR-2964a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.09041
ALDH1L2	Pathway Commons Protein-Protein Interactions	1.0	null
cranium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.177198
Chloroplast stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4183
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPS6	Pathway Commons Protein-Protein Interactions	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34334
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.459217
microtubule organizing center part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.213322
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43617
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2375
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.511
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.78522
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201737
thioproperazine-1390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K36me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994875
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88038
NRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02486
BRD-K11573765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52084
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-11.9659
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1395_KO_Upf2_SRP351098	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.49694
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epstein-Barr Virus_Akata BL clone-4hr starve_None_GSE19761	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.40169
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2433
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE195663_0_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
pc3	HPA Cell Line Gene Expression Profiles	1.0	0.894754
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65789
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44928
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2375
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
AASS	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.41777
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29952
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5364-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01202
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20092
LTBR_INHIBITION - 3 Day_GDS2004_735_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPS10	Pathway Commons Protein-Protein Interactions	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.01038
TK	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.78774
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0077
ATF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT474	CCLE Cell Line Gene Expression Profiles	1.0	2.88053
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917257
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19872
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4XK-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.38758
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216568
UACC-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.93904
BRD-K26954192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73392
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40432
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392309
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2019_KO_Parp1_SRP243891	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.75022
BRD-K68617666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96883
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927572
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K36me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5261_KO|KD_Mir290a/Mir290b/Mir291a/Mir292/Mir292/Mir291b/Mir293/Mir294/Mir295|Tfap4_SRP326984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.30959
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-827	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.1453
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38816
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.809893
Grey cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPL51	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14767
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.1298
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PUSL1	Pathway Commons Protein-Protein Interactions	1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14206
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
MRPL54	Pathway Commons Protein-Protein Interactions	1.0	null
SBC5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32615
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20784
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74515526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07858
CUL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K25811799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28865
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP5C1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.99131
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960045
BRD-K70090544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14379
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73366
BRD-K83300227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05461
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
APP	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07952
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33607
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3174
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990959
KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	3.46859
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11226_KD_Mafg_SRP165897	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.79665
RP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00426561
c-Myc_OE_GDS3321_157_mouse_lung adenocarcinomas alveolar epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.08042
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68635
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NGRN	Pathway Commons Protein-Protein Interactions	1.0	null
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043595
SRF	ENCODE Transcription Factor Targets	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SBC-5	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.94296
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-592	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.15793
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.94645
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.633842
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1462
RPUSD3	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61914
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40511
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20193
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL21	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92963
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	2.18987
TMLHE	Pathway Commons Protein-Protein Interactions	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838029
BRD-K29542628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43327
Ribosome	KEGG Pathways 2026	1.0	null
Anaplasmosis_Leukemic Cell_GSE2600	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43751
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-X6-A8C3-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56824
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16896
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ac	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
Perrault syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
stratum granulosum cerebelli	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15894
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.30118
ARID3A	ENCODE Transcription Factor Targets	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62425
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1909
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K77203880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43876
Perturb_11785_KO_Btnl1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.14683
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.68148
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0472
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11232_KO_Il4/Il10_SRP100781	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.71787
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02086
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC4147934-1755-8794-7-50-S3.xlsx-gene-set_table-MYC_New_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65611
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.713499
BL1475 (PNKP)	NURSA Protein Complexes	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A31962514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41061
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892358
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21385
BRD-K69960043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3963
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.695686
BRD-K20644549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02551
BRD-K16598630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42021
ALDH2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02813
TALL-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.31603
PYCR2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE201042_6_v_1_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.71859
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GO-06A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8947
BRD-K61139423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78519
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.69708
RB1_KD_GSE50532_592_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25946
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.46755
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.8476
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18942
H3K36me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_1_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84494
Perturb_11209_KO_Mettl14_SRP339507	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.66382
OAT	Pathway Commons Protein-Protein Interactions	1.0	null
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.886902
VA-48-RJ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254214
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7209
KDM5A	ChEA Transcription Factor Targets	1.0	null
NDUFV1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18039
hsa-miR-548ae	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09681
NCIH838	CCLE Cell Line Gene CNV Profiles	1.0	1.34497
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889781
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVTOKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
terminal hypothalamus (rostral hypothalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37843
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Mitochondrial ribosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956723
cellular_component	GO Cellular Component Annotations 2015	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838162
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67577
AD-00-WA10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355713
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Cell envelope Sec protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.596
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC6_KO_GDS4375_532_mouse_Foxp3(+) Tregs	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.60108
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.64529
GSE182680,GSE182683_7_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29631
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15758
MRPL14	Pathway Commons Protein-Protein Interactions	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055033
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03273
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44268
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931931
RARS2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-2.34523
intralaminar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00578
GSE145311_1_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3922-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
BRD-K02321382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12362
BRD-K50081142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32743
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0547
DYNLRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35574
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46807
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.10438
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
CTNNB1-20615089-FETAL_BRAIN-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44921
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intrinsic component of synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
skin	HPA Tissue Protein Expression Profiles	-1.0	-0.897482
ACAD9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02734
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.916464
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48935217_S1364_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.77081
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16122
parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061218
SIRT6	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548aj	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
Lamina epithelialis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
PMC12260418-pnas.2425984122.sd01.xlsx-TEAD4_6fraction_test_result-Unnamed_3_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30933750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44468
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
arsenic trioxide	CTD Gene-Chemical Interactions	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DACH1	ChEA Transcription Factor Targets	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7501_RPS13_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.554122
Perturb_15088_KO_Yap1/Wwtr1_SRP303521	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.74669
Perturb_4718_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
HCT116	BioGPS Cell Line Gene Expression Profiles	1.0	1.34343
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36111
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K30656344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.36114
Perturb_7437_KO_YTHDF2_SRP082495	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.01797
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4381
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30025
normal pressure hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.485125
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.12952
hsa-miR-21	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
imatinib_homo sapiens_gpl96_gds3049	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBK-0726-SM-3LK5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19329
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60829
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.110643
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K56214240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10637
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU216	CCLE Cell Line Gene Expression Profiles	1.0	1.7135
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.27829
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69167
ATF1	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.92422
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03966
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL28	Pathway Commons Protein-Protein Interactions	1.0	null
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Walking leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54295
NELFA-20434984-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE169590_6_v_5_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.818
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.64587
NPM1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ribonucleoprotein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
APLF	Pathway Commons Protein-Protein Interactions	1.0	null
TRPM7_defectivemutant_306_GSE23102	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.47734
SP4	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04612
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.925754
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12588
hsa-miR-873	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.9717
gastrointestinal cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_4715_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19538
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46554
rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.665995
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39624517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77013
SLC25A4	Pathway Commons Protein-Protein Interactions	1.0	null
ATAD3B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18661
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904119
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08084
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10381
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
raubasine-1748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223603
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905138
SNU1105_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.72871
Scolex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82107433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96365
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.262
8788_TCFL5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.518044
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.62906
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2777_EXO5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.56494
amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.080735
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0677
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.725
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12695649-41588_2025_2389_MOESM2_ESM.xlsx-GATA6_RIME-_AsPC-1-Gene_Symbol_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35786
PPARG	ChEA Transcription Factor Targets	1.0	null
PMC8384902-mmc2.xlsx-5_POU2F3_high_subtype-Gene_Symbol_POU2F3	Rummagene Transcription Factor Associations 2026	1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942376
DG-75	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.90193
BRD-K97886487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.189
organellar ribosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_14193_KO_PRMT5_SRP149386	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.71739
mitochondrial ribosome	GO Cellular Component Annotations 2025	1.0	null
KIAA0391	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS25	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72865
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YBX1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.6072
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
atrophic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.718039
BRD-K12064774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81096
BRD-K31602464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33426
Sarcoma_SARC_TCGA-PC-A5DO-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523803
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RH41_SOFT_TISSUE	CCLE Cell Line Proteomics	1.0	2.01293
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66257
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3629
trim28_23493425_cd71pluster119plus_sorted_from_bone_marrow_lof_mouse_gpl6887_gse44063	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.253815
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	1.0	1.98915
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WI-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254456
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972116
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46083
FLAD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.53184
BRD-K54538111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04017
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.0075
BRD-K60076175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54856
BRD-K41774018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20494
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.23204
breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.207245
BRD-K94088431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03812
Large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.584
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4697
pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.126526
Perturb_4354_KD_ERK3_SRP238353	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09322
BRD-K70978931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45394
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.998
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1194
CR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00432059
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.419845
Necrosis	CTD Gene-Disease Associations	1.0	2.01663
BRD-K72161690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19682
SK-MEL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29517
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28233
KMS12BM	CCLE Cell Line Gene CNV Profiles	1.0	1.59966
CCNT2	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9531837-pone.0269077.s012.xlsx-EWS-ETV4_ratio_5_p_value_0_05-Gene_name_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75504
BRD-K09598619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51753
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897927
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14665
Golgi-associated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KAT2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8271_SON_P1	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.02792
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K06439119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55798
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10721
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.78298
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46546
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.710098
6-chloromelatonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40387
MYBL2-22936984-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17784
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18312
COLO 849	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.14965
FOS	ENCODE Transcription Factor Targets	1.0	null
BRD-K68073004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02236
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41121
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.251015
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	1.51407
Perturb_3574_KD_OVOL1_SRP056220	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.62865
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65061
BRD-K83272071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03038
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.39873
NCI-H1648	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.19266
BRD-K65488906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55013
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31503
BRD-K90625171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14845
EC-98-KI28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310365
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990335
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4442_KO_Sel1l_SRP318758	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.17446
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pterygium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_70_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
MRPL43	Pathway Commons Protein-Protein Interactions	1.0	null
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01924
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_2_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-633	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9531837-pone.0269077.s012.xlsx-EWS-FLI1_ratio_5_p_value_0_05-Gene_name_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5329-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58005
NCI-H226 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.773
PTHrP_KD_GDS1664_71_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09738
JA-79-II25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205071
USF1	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRPEL1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4109
TGM2_KD_GSE23702_715_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.34808
hsa-miR-124-3p	MiRTarBase microRNA Targets	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67662
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16317_KD_POU2F2_SRP336261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.54615
SPI1	ChEA Transcription Factor Targets	1.0	null
structural constituent of ribosome	GO Molecular Function Annotations 2015	1.0	null
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11696
MB-15-ZF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.661888
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0329
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Esophageal Neoplasms	CTD Gene-Disease Associations	1.0	1.1556
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18956
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CCF-STTG1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5678
ATP5H	Pathway Commons Protein-Protein Interactions	1.0	null
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404998
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.629273
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.62348
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61199074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17625
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193993_5_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208238
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_6_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DCP1A-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.0797
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66745
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71147
Perturb_12318_KD_NRDE2_SRP161520	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.74995
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319391
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930463
TCF3	Pathway Commons Protein-Protein Interactions	1.0	null
mitochondrial large ribosomal subunit	GO Cellular Component Annotations 2015	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.92897
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27492
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-3769-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89694
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232544
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85315
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.906205
IM95_STOMACH	CCLE Cell Line Proteomics	1.0	2.11559
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55251
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548d-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.918525
bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.99233
Ventral posterolateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04473
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05958
KALS1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.59242
H3K36me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.662336
Perturb_8771_OE_MSX2_SRP304247	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.57123
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALDH18A1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07345
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76525
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347422
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09221
cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.112242
BD-61-OO16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264068
GTEX-POMQ-0626-SM-3P61E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877603
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.473092
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75509
BRD-K28785305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.51992
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02901
SLC25A1	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04739
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875421
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20338
Perturb_8867_KD_PNN_SRP063860	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.92001
Prostate adenocarcinoma_PRAD_TCGA-EJ-5532-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55704
CREB1-15753290-HEK293T-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K39639513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24442
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51431
Mitochondrial large ribosomal subunit	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05318
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.634358
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.666402
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.509788
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16874
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16657
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.847243
9600_UPF1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.916901
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
deferasirox_homo sapiens_gpl570_gds3558	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Multiple synapse bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.857
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26216
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16664
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927078
KASUMI-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.51864
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36689
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273731
SETDB1	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59315
GSE184884_6_v_5_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KC-32-GO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331787
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57268
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857676
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.217012
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25714
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27527
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrial membrane	GO Cellular Component Annotations 2023	1.0	null
HCC15	CCLE Cell Line Gene CNV Profiles	1.0	1.61192
BRD-K43418395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21949
nadh dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.336241
MAP4K5_knockdown_199_GSE61497	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.56603
Perturb_15502_KD_GUCY1A1_SRP148609	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.60568
SW620	BioGPS Cell Line Gene Expression Profiles	1.0	1.00769
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21819
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
CUL3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.61327
BRD-K07035171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07192
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40859
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38028
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828243
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4885-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L1236	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3666
IQCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23421
CRCGN016_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.73021
SUCLG2	Pathway Commons Protein-Protein Interactions	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15611
HNRNPA0	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14056_OE_NFIB_SRP281947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.41622
SAP30	ENCODE Transcription Factor Targets	1.0	null
Perturb_2569_KD_HMGCR_SRP216293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.30981
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BE-17-CS60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227043
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.25776
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.98292
BRD-A40010674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00612
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35018
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_ZFP281_21915945	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2768-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08192
BRD-K34985075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25978
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05424
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.54494
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.201475
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14562
TE4	CCLE Cell Line Gene Expression Profiles	1.0	2.3247
5232_MRPL49_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.524979
BA-88-HT15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334069
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347406
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.429011
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.79911
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.676311
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mitochondrial gene expression	GO Biological Process Annotations 2025	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.23472
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92124212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12849
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A60414806_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.96002
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00284
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.993107
mitochondrial inner membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5013
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44288
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.4914
CPT2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.386308
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54794
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.69167
estradiol_homo sapiens_gpl570_gse11352	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.49675
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.78033
Lung squamous cell carcinoma_LUSC_TCGA-66-2778-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
J82	GDSC Cell Line Gene Expression Profiles	1.0	1.98735
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.726827
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pellicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.409869
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.70403
CVB3_3Hour-Infection_None_GSE697	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.99792
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306187
NCI H322M	BioGPS Cell Line Gene Expression Profiles	1.0	0.866077
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01033
MVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03669
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41914
BRD-K06784595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00081
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.18971
SUCLA2	Pathway Commons Protein-Protein Interactions	1.0	null
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49767
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01757
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
periventricular stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35412
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COX4I1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.931865
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_triplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
MRPL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUP-B15	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.31031
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0639
focal dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166431
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-8501-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Submucosal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
hsa-miR-4527	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PDK3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K46526566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1023
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72865
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5488
GSE178267_2_v_0_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60429
SP1	ENCODE Transcription Factor Targets	1.0	null
dorsum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394576
BRD-K28107038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14086
EBF1	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3749
PRKCDBP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.865107
colorectal cancer cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.62959
KYSE-450	GDSC Cell Line Gene Expression Profiles	1.0	1.45277
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BB-87-SF89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248706
TCEAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04013
3050_FDPS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.50547
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SSBP1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16053
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824198
CC-68-YZ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.472113
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68151
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907591
respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.22145
16484322-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.94442
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00775
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.092484
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K72765192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73845
BRD-K67638302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67352
CDK8_knockdown_129_GSE30816	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.84422
MRPS30	Pathway Commons Protein-Protein Interactions	1.0	null
DC-61-QV78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285096
RKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
MRPL40	Pathway Commons Protein-Protein Interactions	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08266
GSE143994_0_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8306
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67283
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11168
TEAD4	ChEA Transcription Factor Targets	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.03362
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.922248
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876026
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25585
BRD-K11057086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4641
19843711-TableS2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K76729384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49896
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1221
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3473
eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292793
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-9.13035
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.04032
H3K36me3_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26794
TAL1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1972	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SX-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82394273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42084
BRD-K91328526_Clomiphene citrate (Z,E)_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sternocleidomastoid muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769855
CD-20-MH57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256421
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76017
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09522
BRD-K51253991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29412
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3518
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.02003
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9296_KD_Stat1_SRP254967	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.45415
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mandibular ramus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.445653
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_7614_KO_LARP1/LARP1B_SRP201361	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.79281
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NP-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tibia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447576
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.451122
Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.96548
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922676
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4423-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.999516
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04299
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.964936
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71505
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1655
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07362
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.03939
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.095
LONP1	Pathway Commons Protein-Protein Interactions	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43461
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
C10orf2	Pathway Commons Protein-Protein Interactions	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.425
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2757
BRD-K06219419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14148
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0041
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72681425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3633
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04738
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.98688
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.993174
BRD-K68544484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68841
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865051
H3K36me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.47799
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836724
GSE228106_0_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TD-48-XJ84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.482529
mitochondrial matrix	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.73037
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064803
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20233
BRD-K33573676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09497
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRAK4_knockout_41_GSE12124	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.79415
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1769
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ECI1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K64246525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31859
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929167
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04381
Lung squamous cell carcinoma_LUSC_TCGA-66-2759-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02096
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SRP14	Pathway Commons Protein-Protein Interactions	1.0	null
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.548378
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11263707-41419_2024_6896_MOESM4_ESM.pdf-14-TCF7L2_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25963
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19546
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.05972
BRD-K63493628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98677
MRPL39	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K04399953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27319
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915953
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1634
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC2866657-pone.0010547.s003.xls-ESE3_corr-Genes_correlated_anticorrelated_to_ESE3_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02659
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98801
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HK2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.85588
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.33407
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Intrinsic component of postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.933582
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2889
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.841339
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.197099
Perturb_14810_KO_Ldah_SRP282425	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3846
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10952_KO_70L02Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43662
ABCB7	Pathway Commons Protein-Protein Interactions	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214158
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73299
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K81277520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15955
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHCHD1	Pathway Commons Protein-Protein Interactions	1.0	null
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293365
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46428
ZNF276	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00451665
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91416
BRD-K35073835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5446
PMC8101445-mbc-32-475-s003.xlsx-HEK_Tim22_KD-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34573818	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47772
hsa-miR-500b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.07875
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11062
GTEX-P4PQ-0726-SM-3NMCR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08647
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8384902-mmc5.xlsx-H2107_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01414
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880214
Mitochondrial envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11062
PF-59-CY33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256974
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28156
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43357
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.541623
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2375
GTEX-UPJH-0726-SM-4IHJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07945
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.661
RB-55-KL42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.56763
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A04258855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28009
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43153
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.93419
TARS2	Pathway Commons Protein-Protein Interactions	1.0	null
DB-54-GQ68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267989
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38197
2-BFI	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48069
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.865107
VSIG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00482077
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4099-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09881
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96776591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14085
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840103
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.307
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968076
P31-FUJ	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.23106
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.31929
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07495
HNRNPDL	Pathway Commons Protein-Protein Interactions	1.0	null
fisetin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43807
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17625
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.984035
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.133223
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14249
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.15995
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
COQ9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21991
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.640461
C6orf203	Pathway Commons Protein-Protein Interactions	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.20007
BRD-K34632780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21291
SLC25A6	Pathway Commons Protein-Protein Interactions	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.7899
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.78462
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060413
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03888
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06925
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149139_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55867695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2666
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.349
BRD-K65207153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92037
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r4 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34728
cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10417
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.07411
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08192
imatinib_homo sapiens_gpl96_gds3042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17555561-Table1	GeneSigDB Published Gene Signatures	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9668
Perturb_4720_KD_Tp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19401
EC-41-PH99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295456
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32578
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57298
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16441
MRPS23	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55218521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73607
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09044
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K84514454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62934
Organelle inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.883058
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891477
BRD-K76147162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10402
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5722
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0941
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374036
hsa-miR-3127-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.34952
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22109
Dyskinetic cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048034
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.76854
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332603
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.25083
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04965
BRD-K71177762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16024
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5631-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128333_2_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59099886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17943
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.17101
YKG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.68928
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04192
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.25207
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9137
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04738
BRD-K34595616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08509
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924738
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
LYSP100-associated nuclear domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30176
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0598
6795_PRPF38B_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.20787
8331_SPC24_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.616887
MUT	Pathway Commons Protein-Protein Interactions	1.0	null
medial geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379875
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.03357
Hypertension	CTD Gene-Disease Associations	1.0	1.24307
BRD-K10634221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44292
GTEX-UPIC-0326-SM-4IHJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25187
MRPL20	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_10330_KO_Dnmt3a/Dnmt3b_SRP214596	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.66926
SMAD2	ChEA Transcription Factor Targets	1.0	null
H3K36me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46285
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08286
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.895
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849275
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55053106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17436
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984839
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NFK9-1726-SM-3TW8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78315
Mitochondrial membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE173201_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KYSE180	CCLE Cell Line Gene CNV Profiles	1.0	1.47225
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15845
mitochondrial part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22589
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XC-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UQCRC1	Pathway Commons Protein-Protein Interactions	1.0	null
Metabolism of proteins	Reactome Pathways 2024	1.0	null
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70882
RELA	ENCODE Transcription Factor Targets	1.0	null
PMC10654515-41467_2023_43245_MOESM4_ESM.xlsx-Putative_ERG_binding_proteins-Unnamed_1_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE132386_1_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.02562
ribonucleoprotein complex	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTNNB1-20615089-FETAL-BRAIN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17476
KB-65-GP42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233936
periventricular stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28302
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30041
PMC6488577-41598_2019_43010_MOESM2_ESM.xlsx-Proteingroups_MBD3_pos-Gene_names_MBD3	Rummagene Transcription Factor Associations 2026	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056533
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Mitochondrial degradosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
VD-76-SO91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.548874
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.54709
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15611
Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39965317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16306
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36087
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.961552
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00735
TFB1M	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-387 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00578
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1663
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_DMAP1_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_5836_KO_Bgn/Dcn_SRP295503	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.11356
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4666-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.62357
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840313
POU5F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.879934
Hot Flashes	CTD Gene-Disease Associations	1.0	1.09963
Acne	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.818
H3K36me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28629
TE-5	GDSC Cell Line Gene Expression Profiles	1.0	2.4279
BRD-K16118844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00739
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A6G5-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_8_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39838
stomach	HPA Tissue Protein Expression Profiles	1.0	0.88974
T-24	GDSC Cell Line Gene Expression Profiles	1.0	1.45149
HIV - Human immunodeficiency virus infection_Peripheral blood mononuclear cell_GSE2171	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.68312
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67601
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.81545
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.10838
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-14	GDSC Cell Line Gene Expression Profiles	1.0	1.98466
CRCGN012_HEPG2_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09452
methotrexate_homo sapiens_gpl570_gse11440	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_2317_KD_PRPF31_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.3086
BCL7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65606
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7039
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.303655
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41135617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47653
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953471
SK-MEL-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.78527
AE-64-KN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299649
U87MG_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	4.19165
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10462
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-0.805704
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043148
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7485
LB-65-SM65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.561826
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272643
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834874
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1671
tsc1-tsc2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.158129
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47955
r3 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28302
BRD-K69496360_7831785_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.434899
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18412
BRD-K01096898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0593
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.48463
LRPPRC	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Aspartate carbamoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
Cancer of thyroid_Thyroid_GSE5364	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.00296
TP53BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25195
Abdominal obesity-metabolic syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.601
BRD-K15502859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47539
GSE202434,GSE202438_7_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.883796
CRCGN012_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12411
KB-78-BE93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.366444
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RO-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68952
FASTKD2	Pathway Commons Protein-Protein Interactions	1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.76985
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56022813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00972
Perturb_17442_OE|Mut_Tal1|Akt_SRP366791	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.94787
hsa-miR-4302	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
BRD-A20697603_T8902_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
MTHFD1	Pathway Commons Protein-Protein Interactions	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7092
ZNF143	ENCODE Transcription Factor Targets	1.0	null
outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212936
ECH1	Pathway Commons Protein-Protein Interactions	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861673
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_3_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32593
Epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882496
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00794
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12006
AFG3L2	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242083,GSE242098_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mandibular condyle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476979
BRD-K47309161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14156
Learning disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.662
SRF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16852
BA-84-TD72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244643
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RM2N-0626-SM-48FD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842891
BRD-A66566298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52088
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882309
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.64422
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16403
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18028
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.899219
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.59285
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31597
BRD-K05000526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4096
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79073
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894179
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.939018
P12-ICHIKAWA	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.08247
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14701
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EB-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44141416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00962
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
10244_ZNF260_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.541634
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49374
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.717717
ETFA	Pathway Commons Protein-Protein Interactions	1.0	null
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.862685
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.910775
JARID1A-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K42034238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19855
YAPC	CCLE Cell Line Gene CNV Profiles	1.0	1.42912
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970082
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4763-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
AE-88-WQ63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308902
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35364
BRD-K76135327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02384
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471939
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.219057
jaw	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.195492
TOP1	Pathway Commons Protein-Protein Interactions	1.0	null
CD109	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00640697
Perturb_12324_KD_PHF20L1_SRP188318	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BB-23-PM31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317994
CNOT3-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36255
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FC-85-OX77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368825
T-REx 293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.086996
MRPL13	Pathway Commons Protein-Protein Interactions	1.0	null
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36754
generalized dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.450701
RALYL	Pathway Commons Protein-Protein Interactions	1.0	null
GLUD1	Pathway Commons Protein-Protein Interactions	1.0	null
BC-15-EL49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623952
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530113
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93552
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26942
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Essential Thrombocytemia_Thrombocyte_GSE2006	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.73886
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.39689
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24415
arm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.161262
CRCGN017_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05975
FBL	Pathway Commons Protein-Protein Interactions	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943045
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00316
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01278
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21343
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27355
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03796
POLDIP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYCN-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25739
TRIM28	ChEA Transcription Factor Targets	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857016
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2347
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903132
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43055
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_hexaplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACADVL	Pathway Commons Protein-Protein Interactions	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-97-BI36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.556309
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951649
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.275202
BRD-K48069820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78344
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29031
hsa-miR-4252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866643
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC9A3_KO_GDS3323_495_mouse_colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38222
hsa-miR-541	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84757
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.53764
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VDAC3	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43001
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25559116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.93462
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236627
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.693033
AC-47-YZ27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238989
1395_CDC26_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.648788
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.793543
BRD-K57969466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59814
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05119275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32253
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.13895
OMC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.84348
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.59935
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827359
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.97905
MRPS11	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
MAPK14_knockout_14_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.75554
H3K36me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTLL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03694
Mitochondrial ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.49
BRD-K06845853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23322
BRD-K44549496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11495
BRD-K91387865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06894
Head capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57051157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53529
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectal cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCFC1	ENCODE Transcription Factor Targets	1.0	null
kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.098558
LETM1	Pathway Commons Protein-Protein Interactions	1.0	null
PRDX4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979888
SREBF2	ChEA Transcription Factor Targets	1.0	null
transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.077205
BRD-K50004365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10692
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11864
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.302698
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B6-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.36707
MD-86-UW46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205051
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BJ-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870844
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846839
POU2F2	ENCODE Transcription Factor Targets	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.183935
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day2_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.4345
hsa-miR-597	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K29143088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02098
TE-87-FM14_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271602
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AE-04-SN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207951
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
RELA_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHCHD2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23852
CRCGN008_HEPG2_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3419
epithelial cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41651
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43086
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
JF-30-FW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255113
BRD-A66369147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2208
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.09718
ZNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04521
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.18658
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37209
SW954	GDSC Cell Line Gene Expression Profiles	-1.0	-1.78726
DETROIT562	CCLE Cell Line Gene CNV Profiles	1.0	2.29508
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	1.0	2.02776
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.20286
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	4.55735
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.322414
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858941
AP2M1	Pathway Commons Protein-Protein Interactions	1.0	null
PLAGL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660506
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.396752
AKT2_knockout_221_GSE19079	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.2727
gata4_21746915_heart_lof_mouse_gpl6246_gds3931	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.447563
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929968
GSE143643,GSE143644_4_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
retina	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.852994
CRCGN016_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06873
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101077
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55999
BRD-A73559168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23527
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4011
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NENF	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.37926
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH441	CCLE Cell Line Gene CNV Profiles	1.0	1.54788
MRPL49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84388
Perturb_11004_KO_Nhlh2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.44291
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84028
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19294737-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
10348_ZNF423_ENST00000262383.2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.62314
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70882
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
H3K36me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06039
Perturb_15008_KD_Klf5_SRP341620	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.74281
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16664
Perturb_3750_KD_NORAD_SRP149071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.73548
NHE3_Deficiency_GDS3323_599_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5806898-pbio.2004411.s003.xlsx-MR_plot_data-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Myocardial Infarction	CTD Gene-Disease Associations	1.0	1.38527
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infertility, Female	CTD Gene-Disease Associations	1.0	1.47322
BRD-K35942122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50588
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-506-MAFA_MAFA	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2771-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.26318
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.849137
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL18	Pathway Commons Protein-Protein Interactions	1.0	null
Fibroblast_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
AKAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08126
H3K36me3_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PABPC3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22098
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80246
Translation	Reactome Pathways 2024	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.872741
NB-12-ZK38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451331
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31247
COPS5	Pathway Commons Protein-Protein Interactions	1.0	null
CLPX	Pathway Commons Protein-Protein Interactions	1.0	null
N-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1964
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972338
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01928
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00742
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2782-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CAL27	CCLE Cell Line Gene Expression Profiles	1.0	1.57292
mitochondrial ribosome	GO Cellular Component Annotations 2023	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12697_KO_Ezh2_SRP222765	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.30486
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23431
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-654-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLIRP	Pathway Commons Protein-Protein Interactions	1.0	null
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
MIM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.807172
organelle part	GO Cellular Component Annotations 2015	1.0	null
BRD-K47275094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61338
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.383895
MRPL3	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K61034310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98064
BRD-K28579021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17525
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18923
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K91516693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09668
RCOR1	ENCODE Transcription Factor Targets	1.0	null
ZNF821	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48834
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MRPS34	Pathway Commons Protein-Protein Interactions	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053889
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34276
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882872
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21586
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969545
BRD-K34254821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23247
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42491
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329511
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22916
Depression_Cerebral cortex_GSE12654	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.57721
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dense fibrillar component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
CAL-39	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25918
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918872
GTEX-U4B1-0926-SM-4DXUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03093
hsa-miR-671-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CRCGN016_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3883
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.58212
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00486
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RGS13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599836
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74751
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12961_KO_NMNAT1_SRP313669	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCOR1	ENCODE Transcription Factor Targets	1.0	null
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.889131
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193993_0_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48406740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1334
GSE185922_1_v_2_riok2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989345
TUHR4TKB_KIDNEY	CCLE Cell Line Proteomics	1.0	4.12844
Perturb_10129_KD_eHDAC6_SRP090317	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.81783
TAF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracranial hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.141703
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.968262
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.073718
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-665	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
medial geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.279659
SUCLG1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.95007
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5806
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06328
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
17676974-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Perturb_11702_KD_MIR31HG_SRP051359	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myositis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.537731
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37138
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21826560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11549
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998573
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63358
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19695
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212315
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985609
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.81814
TF-04-RX73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.499261
Intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Fine root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein complex subunit organization	GO Biological Process Annotations 2015	1.0	null
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-95-OQ30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214019
TCF3	ENCODE Transcription Factor Targets	1.0	null
AA-58-FJ71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277834
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60696
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60364
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44034
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.96277
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13665
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Anemia	CTD Gene-Disease Associations	1.0	1.09857
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.21868
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149075_2_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mitochondrial ribosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MRPL53	Pathway Commons Protein-Protein Interactions	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7330_KO_CD34_SRP156691	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.6074
RPS23	Pathway Commons Protein-Protein Interactions	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69982
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K47052171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18918
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SCNN1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03077
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1565
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00049
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37643
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43341
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MNAT1_Deficiency - Ablation_GDS2561_689_mouse_Heart - 2 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL48	Pathway Commons Protein-Protein Interactions	1.0	null
RPS4X	Pathway Commons Protein-Protein Interactions	1.0	null
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.99952
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02843
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169155_5_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MRPL44	Pathway Commons Protein-Protein Interactions	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.81411
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843198
BRD-A77164655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17883
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE154577_13_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.10739
NFATC1	ENCODE Transcription Factor Targets	1.0	null
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044901
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_24Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.76195
9600_UPF1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.22895
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07492
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.48833
BRD-K34966483_7332649_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.12771
MXI1	ENCODE Transcription Factor Targets	1.0	null
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73736
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226719
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.135026
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103372_0_v_3_smad1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06295532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19264
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042901
CREB1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS29	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
5927_OGDH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.519676
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KALS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35863
NSUN4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K67126097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81694
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.3716
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE234514,GSE234516_1_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.829127
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88558
Heart Diseases	CTD Gene-Disease Associations	1.0	1.18259
upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066796
integrin alpha6-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.579251
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.17365
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982635
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64660038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17359
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84745303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33062
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80618
Lung squamous cell carcinoma_LUSC_TCGA-39-5011-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS22	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-339-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.0283
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-2.86821
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
bromopride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4108
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCMV_24Hour-AG_pretreatment_20173022_GSE17948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.37093
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222938
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.19014
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061003
UBTF	ENCODE Transcription Factor Targets	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08324
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.46523
GSE135352_6_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEP57	Pathway Commons Protein-Protein Interactions	1.0	null
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26535
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48167
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.716651
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DLST	Pathway Commons Protein-Protein Interactions	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.818
6024_PABPC1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.56291
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PANC-02-03	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.09797
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10105
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883088
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C1-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD2-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.168985
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7651-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.385565
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045902
METTL18	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880654
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949696
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50574
NCIH28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52615
BRD-K61189585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1638
GSE129370_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ILKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39467
NDUFS3	Pathway Commons Protein-Protein Interactions	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.3686
Perturb_6487_OE_MDM2_SRP302203	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.67738
GSE125782_0_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17773
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838162
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99065
MMAB	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29958
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71866
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914393
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24446
BRD-K55169051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21357
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9148
prostate gland	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-2.07208
CRCGN016_MCF10A.TP53.M_24H:N24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41813
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.86557
6708_PPWD1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.784131
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81041
hsa-miR-3941	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HB-75-KT12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213699
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29901
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.988261
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11062
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193993_5_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02638
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47582411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75516
CRCGN011_HEPG2_24H:I09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51195
BRD-K99074976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38911
PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
mitochondrial permeability transition pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.229888
mitochondrial membrane	GO Cellular Component Annotations 2015	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.421112
H3K36me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.895553
MRPL12	Pathway Commons Protein-Protein Interactions	1.0	null
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26653
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.27561
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76736
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69905
central nervous system hereditary degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.350452
BRD-K56241426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50705
MRPS14	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8530322-pone.0258316.s002.xlsx-GG_776_TH17-AA_776_TH17-Symbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6755_KO_UPF3A/UPF3B_SRP327782	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.79467
PC-68-DU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313634
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38967
large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0217
Medial group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08926
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83811
RPS7	Pathway Commons Protein-Protein Interactions	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00104
BRD-K49530286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48682
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81052
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12659
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64578
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
organelle inner membrane	GO Cellular Component Annotations 2015	1.0	null
MRPL52	Pathway Commons Protein-Protein Interactions	1.0	null
GSE144838_7_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39709957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69786
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24944
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69564473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68814
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46473
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.07576
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57761
SFXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02872
MRPL4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K55144248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63077
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02866
prolactinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166995
Perturb_9562_KO_Ogt_SRP110508	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.91942
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988344
BRD-K28522188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20719
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908587
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BQ-01C-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2568_KD_HMGCR_SRP216293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.3495
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A5ND-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10475
SMAD2-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.237009
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9673_KO_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.99542
BRD-K61370861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64225
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09426
periventricular stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02366
mitochondrial translational elongation	GO Biological Process Annotations 2015	1.0	null
mitochondrial matrix	GO Cellular Component Annotations 2023	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06233
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18363
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
Perturb_7232_KO_ADIPOR2_SRP285935	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.37214
BRD-K70565285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28114
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.832995
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCCC2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15482
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BR-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09081
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EP-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28166
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_7242_KD_CNOT1_SRP285534	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.7027
Taproot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.30451
BRD-K70183558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33112
single-organism biosynthetic process	GO Biological Process Annotations 2015	1.0	null
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2436
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60661
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.96504
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16839
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44325
BL5657 (ANKZF1)	NURSA Protein Complexes	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE2429	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.42031
GSE110178_1_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5137
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LV-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTPAP	Pathway Commons Protein-Protein Interactions	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01139
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917727
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20826
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.94817
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K22298558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90748
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26866
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960889
BRD-K18385869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23009
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829985
BRD-K66643401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74741
CRCGN015_MCF10A_48H:J06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03386
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20847
9886_XAB2_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.19352
UQCRFS1	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17456
16618758-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
GSE254517_1_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49974
CRCGN016_MCF10A.WT.HP_24H:B13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15252
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84257
PHB2	Pathway Commons Protein-Protein Interactions	1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01486
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33241
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Abdominal obesity-metabolic syndrome 1	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.601
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.17629
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3292
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43199
BRD-K36689392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17747
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95173
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	0.877964
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45445
SNU738	CCLE Cell Line Gene Expression Profiles	-1.0	-2.31009
CEBPB	ENCODE Transcription Factor Targets	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
H3K9me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973185
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ribonucleoprotein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K12589632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12536
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12671_KO_Bptf_SRP191908	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.65998
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71451
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.28548
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15913
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5326-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.44264
BRD-K96425583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00352
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892558
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24665
adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.509675
MRPS15	Pathway Commons Protein-Protein Interactions	1.0	null
structural molecule activity	GO Molecular Function Annotations 2015	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.691463
Perturb_12511_KD_HAPSTR1_SRP377309	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.91395
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.304
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27725
MBL2	Pathway Commons Protein-Protein Interactions	1.0	null
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13127
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.382
nerve compression syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.279367
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.62958
mitochondrial part	GO Cellular Component Annotations 2015	1.0	null
GTEX-X5EB-1426-SM-46MVW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826935
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75944
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273461
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.9709
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(ZEBOV)_1hr_Macrophage_22028943_GSE31747	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-4.05493
NOA1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06491
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41031262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04723
Daudi	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.28445
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.72504
Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS936T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47223
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREBF1	ChEA Transcription Factor Targets	1.0	null
BRD-A56427952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14402
Mitochondrial translation initiation	Reactome Pathways 2014	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04634
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.23233
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0641
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23451
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61946
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56734
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084062
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.870611
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPS27	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9531837-pone.0269077.s012.xlsx-EWS-ERG_ratio_5_p_value_0_05-Gene_name_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11353
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.019
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K48541282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67629
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14811
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045296
Brain Lower Grade Glioma_LGG_TCGA-VV-A829-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.716751
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.781894
BRD-A84867566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25265
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22177
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K05802716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39491
EC-82-LV30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00206
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61353
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984057
PMC12188705-msphere.00110-25-s0007.pdf-81-ZBTB11-AS1_ZBTB11	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998908
TMEM177	Pathway Commons Protein-Protein Interactions	1.0	null
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.63384
Citrullinemia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.337
IGF2BP1	Pathway Commons Protein-Protein Interactions	1.0	null
NEK10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00468871
PMC3290552-pone.0032232.s006.xls-MUC4-KD_vs_Mock-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275094
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13003
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0226-SM-4JBHG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994264
VDAC1	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17468
WBSCR16	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K15400067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.538
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
HFL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73830970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19227
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3176	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832271
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38731
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.68312
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99402
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08084
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCU	Pathway Commons Protein-Protein Interactions	1.0	null
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MES-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.15724
BRD-K68438316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28465
BRD-K45516283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2307
Perturb_14119_KD_RPS6KB2_SRP187713	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.59948
Intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.950947
BRD-K17889110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37335
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.29873
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927572
SKM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49686
Medial geniculate complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14915
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6127
Perturb_12201_KO_ZEB1_SRP178052	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.85824
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5440-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3602
BTK_mutant_1_GDS1346	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.192294
2977_FASTKD2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.56917
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28601178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32564
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_8838_OE_MLLAF4_SRP293797	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.39529
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.86043
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HK1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199899_1_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04909
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00835
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945949
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S16_LF_C2_8h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43485
A498	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5936
Mitochondrial translation termination	Reactome Pathways 2024	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24796
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2655-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STOML2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18624
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14153
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4487	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
DA-83-IZ87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207287
TFAM	Pathway Commons Protein-Protein Interactions	1.0	null
7275_RGS14_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.523751
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70972
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISCA1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cardiomegaly	CTD Gene-Disease Associations	1.0	1.0204
PBX1	ChEA Transcription Factor Targets	1.0	null
NCI-H1395	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66803
CHD2	ENCODE Transcription Factor Targets	1.0	null
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DF-84-RT50_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.463508
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
TGM2_KD_GSE23702_713_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.09561
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25506
HDAC2	ENCODE Transcription Factor Targets	1.0	null
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22709
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6178
hsa-miR-548z	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.205916
Learning Disorders	CTD Gene-Disease Associations	1.0	1.30788
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02151
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27384
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.824686
Perturb_11772_KO_18O10Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.77873
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.895156
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22189453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09086
FD-79-TC61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451577
TBP	ENCODE Transcription Factor Targets	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32007
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02609
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A5	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.997613
POLRMT	Pathway Commons Protein-Protein Interactions	1.0	null
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.37809
BRD-K64860662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07639
TMEM89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0895
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47046
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02425
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337236
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48032
HS742T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63048
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74357
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07578
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
translational elongation	GO Biological Process Annotations 2015	1.0	null
epicondylitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.708767
Disorders of Sex Development	CTD Gene-Disease Associations	1.0	1.28395
SDHA	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3663-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918613
RIBC2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-0626-SM-2YUN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17337
Perturb_6417_KO_TP53_SRP274402	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.23357
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14202
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.97638
MRPS21	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.968691
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889781
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
5232_MRPL49_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.505445
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937563
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.697725
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18033
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0296
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.895902
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.58681
BRD-K66216147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23417
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.3574
Perturb_3850_KD_AKAP12_SRP254561	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.51951
Tooth resorption	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4650-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
CHD1	ENCODE Transcription Factor Targets	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
Adrenomedullin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58497
MRPS35	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02745
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28619
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838162
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29465
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BA-86-AL61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324335
hsa-miR-3922-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
POLR2A	ENCODE Transcription Factor Targets	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.84692
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.553627
cytosolic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.348725
Clathrin coat of trans-Golgi network vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.172402
mitochondrial translation	GO Biological Process Annotations 2025	1.0	null
496100415_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39668
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846439
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE155162,GSE155169_1_v_3_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.7143
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.511125
CDH2	Pathway Commons Protein-Protein Interactions	1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29072
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18923
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897651
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973809
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8325
Perturb_9669_KO_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.15687
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06863
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_65_KO_Cabin1_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.4827
Mitochondrial translation	Reactome Pathways 2014	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.67693
fibromyalgia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.843802
BRD-K67626198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21623
Chloroplast ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
NRF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JE-22-JR20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558147
BRD-K52245873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13586
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.911958
BRD-K12119989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16298
GSE206516,GSE206518_5_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.53391
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30811
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95322
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43075
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein complex disassembly	GO Biological Process Annotations 2015	1.0	null
borderline personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.827409
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829329
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25185
BRD-K94766933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34591
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06437
MRPS31	Pathway Commons Protein-Protein Interactions	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.446564
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889781
9587_UMPS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.743708
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30433
Plastid ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.908
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.79085
hsa-miR-1207-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
BE-71-AV63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355937
somatoform disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.172544
Mitochondrial respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04416
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.88584
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02949
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859975
Lung squamous cell carcinoma_LUSC_TCGA-34-5241-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
igr1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CNOT3	ChEA Transcription Factor Targets	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23563
H3K36me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11154_KO_p62_SRP069010	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.64208
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PCNA-p21 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0167
BRD-A69786436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42448
MRPS17	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE229973_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843679
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.949562
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040252
Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-7.33686
attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.24993
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL239 (RAD17)	NURSA Protein Complexes	1.0	null
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03121
GRSF1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K72255851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52697
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49847
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cystitis	CTD Gene-Disease Associations	1.0	1.03308
Weight Gain	CTD Gene-Disease Associations	1.0	1.57426
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52018
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15236933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16905
Adrenocortical carcinoma_ACC_TCGA-OR-A5KT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.36858
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.47534
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67234
BRD-A37523642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19168
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36028
CHRM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536441
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC2A4	Hub Proteins Protein-Protein Interactions	1.0	null
GSE152734,GSE152735_1_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04834
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862267
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K71247208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04926
BRD-K02070226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5496
ORAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07103
496100412_FWM_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42017
BL922 (CUL9)	NURSA Protein Complexes	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.158129
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.91178
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27284
Sarcoma_SARC_TCGA-HS-A5N7-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3748_KD_NORAD_SRP149071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.20101
BRD-K61087440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92684
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
4768_MAGEC2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.557011
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053415
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A24524033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19941
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45952
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17845
BC-75-FA82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292337
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.76175
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TY-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04738
BRD-K39913135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22117
PMC4728380-ncomms10153-s8.xlsx-High_affinity_MYC_Targets-Unnamed_0_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cisplatin_homo sapiens_gpl570_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K96075847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19479
GJB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477126
GSE202434,GSE202438_12_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58902
mitochondrial inner membrane	GO Cellular Component Annotations 2023	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.61953
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87536
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3772
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186096
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
hydroxyamphetamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44261
Perturb_6856_KD_CNOT1_SRP287793	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.75799
Anorexia	CTD Gene-Disease Associations	1.0	1.05757
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16672
SMG7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0064071
Perturb_10956_KO_Adamts15_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.20549
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE210476_9_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7999
Perturb_12364_KD_SON_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.40106
BRD-K21990111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19583
AC-92-HS43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35127
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.83574
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HeLa cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	0.904166
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mitochondrial ribosome	GO Cellular Component Annotations 2015	1.0	null
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K68890376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42688
NCI-H441	GDSC Cell Line Gene Expression Profiles	1.0	1.92119
hsa-miR-33b	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13973870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58029
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80246
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04071
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46197
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11574_KO_miR375_SRP273175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.72727
MRPL22	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00182
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16466
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54806
NR3C1	ENCODE Transcription Factor Targets	1.0	null
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864057
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.76336
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acquired Immunodeficiency Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
blepharospasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.539667
MRPS7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.916252
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889095
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A4EO-06A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16497
KCNK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00426073
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54389
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2719
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33678
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21781
BRD-K31408750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48413
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.773661
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05068
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Type 1 diabetes mellitus_pancreatic islet_GSE2254	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.63178
NDUFS8	Pathway Commons Protein-Protein Interactions	1.0	null
MEF2D_KD_GDS4759_339_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
colorectal adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0294
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.686222
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953834
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
osteoarthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05807
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04188
BRD-K81131499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52344
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26222
glossopharyngeal nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.921736
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21051792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53013
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.876519
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378741
GSE203158_0_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ribosomal subunit	GO Cellular Component Annotations 2015	1.0	null
AA-62-HP31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.618376
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0757
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96624721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66479
BRD-K46703028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31573
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37702
MRPS18A	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_Activation - 8 hours_GDS2025_725_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
pioglitazone_mus musculus_gpl2897_gse8806	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.215992
SLC25A13	Pathway Commons Protein-Protein Interactions	1.0	null
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03807
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07451
astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.320817
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418492
UACC-893	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15367
ZR75_1	BioGPS Cell Line Gene Expression Profiles	1.0	2.00077
communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.823308
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
SW962	GDSC Cell Line Gene Expression Profiles	1.0	1.82872
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83494
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BTK_knockout_2_GDS1346	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.122176
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04972
H3K36me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6_KO_GSE27896_383_mouse_Foxp3+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RPS24	Pathway Commons Protein-Protein Interactions	1.0	null
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.0302
PHB	Pathway Commons Protein-Protein Interactions	1.0	null
PTHrP_KD_GDS1664_438_human_MDA-MB-231	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21526
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34026
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934174
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sensorimotor area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
BRD-A36630025_-666_HCC515_24.0_h_0.35_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_11771_KO_10M04Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.8903
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.926566
BL2094 (MSH2)	NURSA Protein Complexes	1.0	null
NOD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00502611
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4335056-pone.0116726.s005.xlsx-X-ChIP_NOT_TX100_QE-GENE_Official_symbol_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Combined oxidative phosphorylation deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.855
CECR5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ICT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934006
Mitotic fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
ALG1	Hub Proteins Protein-Protein Interactions	1.0	null
hsa-miR-544b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K82823857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3669
Perturb_5292_KO_Dgcr8_SRP137730	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.18769
BRD-K26582498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05972
DARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.169
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53718
USF2	ENCODE Transcription Factor Targets	1.0	null
S0-EE-Y79N_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205323
TRUB2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4956
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7862
5908_NUTF2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.552715
hemoglobin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.280716
CRCGN017_MCF10A.WT.HP_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71885
BRD-K37049577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04337
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35412
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530038
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956723
znf148_21828133_erythroblast_lof_human_gpl571_gse31092	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.42111
SLC25A12	Pathway Commons Protein-Protein Interactions	1.0	null
SMIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52868
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54613
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63665694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11493
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983857
line14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.028
MRPS24	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84845
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54143
H3K36me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6857_KD_CNOT7/CNOT8_SRP287793	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.16005
CRCGN017_MCF10A.TP53.M_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09501
BF-26-MB27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414247
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28929
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Escherichia coli infection of the central nervous system_CNS - Brain (MMHCC)_GSE3253	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.81796
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.959157
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53889798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52644
r2 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02069
ALDH1B1	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9692_KD_TCF4_SRP188467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.07361
mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25041
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL10	Pathway Commons Protein-Protein Interactions	1.0	null
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42269
organellar ribosome	GO Cellular Component Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63994
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.932578
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.76157
BRD-K12011077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73943
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64183190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02118
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	3.30176
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-97-KP88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306617
Perturb_2516_KD_YAP1_SRP181909	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.39786
hsa-miR-3150a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K74712962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01445
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875671
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12072
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.153574
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356184
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.26102
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.898595
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45662
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.23492
MAFK	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_8363_KD_MNX1AS1_SRP396489	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23795
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K07274638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33325
COLO-800	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.43846
BRD-K68618894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4223
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.57027
hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.149378
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0074
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11938
cryptosporidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.323365
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989073
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KASUMI1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82392
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10209
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05275
Perturb_6053_KD_PRMT1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11492
cisplatin_homo sapiens_gpl201_gds3101	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861452
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIX5	ENCODE Transcription Factor Targets	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAPCA2B	CCLE Cell Line Gene Expression Profiles	1.0	1.49988
SLC25A11	Pathway Commons Protein-Protein Interactions	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.62944
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889781
colon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
laminin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.086907
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.33966
Brain Lower Grade Glioma_LGG_TCGA-DH-5141-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL27	CCLE Cell Line Gene CNV Profiles	1.0	1.82965
E2F4	ENCODE Transcription Factor Targets	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149760_3_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42829
pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.857315
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903524
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8107
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.909165
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15038
BRD-K78972225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64496
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRPS26	Pathway Commons Protein-Protein Interactions	1.0	null
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317984
BRD-A76899420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05441
BRD-K36883526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44166
Gfi1b_OE_GDS4302_425_mouse_AMuLV (pro-B Abelson leukemia virus transformed) cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	0.88974
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ERG	ChEA Transcription Factor Targets	1.0	null
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97978
organelle organization	GO Biological Process Annotations 2015	1.0	null
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.601
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
ATP5A1	Pathway Commons Protein-Protein Interactions	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09411
MRPL24	Pathway Commons Protein-Protein Interactions	1.0	null
RBFA	Pathway Commons Protein-Protein Interactions	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093892
Perturb_2114_KD_SF3B3_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.6764
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.581
BRD-K63500288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09236
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.974953
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.98048
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51656
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A43076080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41198
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
BRCA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00424288
macelignan	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11626
Colitis	CTD Gene-Disease Associations	1.0	1.04757
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.540477
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19496
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63112
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40366
GSE190761_0_v_1_samd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUP-HD1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.1817
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
nuclear chromosome part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047538
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82825
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.19064
Liver Diseases	CTD Gene-Disease Associations	1.0	1.22436
MYOD1	ENCODE Transcription Factor Targets	1.0	null
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.563617
PMC10624900-41467_2023_42825_MOESM13_ESM.xlsx-Module_24-NFYA_NFYA	Rummagene Transcription Factor Associations 2026	1.0	null
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00724
peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175411
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.856787
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21405
BRD-K82857306_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K28006645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60098
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61497
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFRC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00658317
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-575	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0597
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.828639
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00044
Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6491-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.368624
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14185
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TF-77-DW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378802
Trolox C-1734	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TGM2_KD_GSE23702_716_human_NB4 cells, 72h ATRA-induced differentiation	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.428018
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.01843
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54833
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929498
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27103
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCFD1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PECAPJ34CLONEC12	CCLE Cell Line Gene Expression Profiles	1.0	1.50632
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873475
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
fat_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.879332
MOGS	Pathway Commons Protein-Protein Interactions	1.0	null
DMS-273	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44375
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-3.19228
BRD-K23704908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.59076
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.557897
BRD-K37595074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80554
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23243
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27883
HARS2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860913
GTEX-QDVN-1326-SM-48TZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27304
KLF1	ChEA Transcription Factor Targets	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72631
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QLQ7-1926-SM-2S1R6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956857
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.96922
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17376
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2B	ENCODE Transcription Factor Targets	1.0	null
BRD-K43456755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04893
cellular process	GO Biological Process Annotations 2015	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.97496
Ribosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1581
FRA10AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62106
proton-transporting two-sector ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.23
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4136
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63898
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
PF-382	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.99169
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-Vietnam-1203-2004(H5N1)_24Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.70366
BRD-K24292260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44301
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15711
Albedo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2567_KD_HMGCR_SRP216293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.15993
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_2_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77369
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
APC2	Pathway Commons Protein-Protein Interactions	1.0	null
PSMB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43368
EOMES-21245162-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.20196
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.32738
metabolic process	GO Biological Process Annotations 2015	1.0	null
TIMM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00196
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOV10	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939423
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skeletal muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K36me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23802
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387413
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79292
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21574
BRD-K33906096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10218
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412575
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00943
GSE112365_0_v_1_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9384
55S ribosome, mitochondrial	CORUM Protein Complexes	1.0	null
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324585
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1671
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6411037-NIHMS981149-supplement-4.xlsx-Table_S3D-Table_S3D_Result_of_GSEA_with_human_ST-EPN_gene_set_DEGs_in_PDGFA_tumors_relative_to_RELA_fusion_tumors_are_listed_in_the_table_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10976_KO_Dlue7_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.30403
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3202
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12809
lumbar spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.644884
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33744
Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	0.88974
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978766
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21502
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5806
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.499853
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
SHMT2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K53050301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08153
cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.48893
SP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948649
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0303
juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260267
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLM1	CCLE Cell Line Gene Expression Profiles	1.0	1.68952
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	1.0	3.21628
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4445
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6881
BRD-K22510845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07283
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272773
BRD-K92569554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52949
BRD-K26836050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01872
Perturb_7665_KO_SNORD45C_SRP257547	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.00025
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.50446
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918571
BRD-K36796440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56168
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32034
GTEX-RWS6-0726-SM-47JXI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892958
EOMES-21245162-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE142019,GSE142021_10_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.43635
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.923474
IC-87114	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
5888_NUP155_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.0356
GTEX-XMK1-0226-SM-4B65D	GTEx Tissue Sample Gene Expression Profiles	1.0	3.71144
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4727-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09146
BRD-K66802550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62405
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33626
GSE57871_5_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211151_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05579
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92672
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.93227
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
BRD-K88820027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03843
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03571
BRD-K40260328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23967
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11842_KO_Stra6l_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.99197
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0794
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
prostate	HPA Tissue Protein Expression Profiles	1.0	0.88974
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2158
BRD-K83122599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04246
MDAMB468	CCLE Cell Line Gene Expression Profiles	1.0	2.3484
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Noc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.253
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.824875
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE5	CCLE Cell Line Gene Expression Profiles	1.0	1.50825
MYBL2	ChEA Transcription Factor Targets	1.0	null
THNSL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311554
Amnioserosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838162
BRD-K14534138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57007
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94423
HSD17B10	Pathway Commons Protein-Protein Interactions	1.0	null
MTIF2	Pathway Commons Protein-Protein Interactions	1.0	null
MAPKAPK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00260289
Perturb_14500_KD_RUNX1_SRP265128	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.32816
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10853_KO_Mkp1_SRP169858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mitochondrial metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
MRPL21	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K04930806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08271
Skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE198794_0_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	2.60387
Perturb_10150_KO_FOXK2_SRP251223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.3129
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1409
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1744
knee	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.800626
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222917
TEAD4	ENCODE Transcription Factor Targets	1.0	null
cisplatin_homo sapiens_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41133627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06461
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35524
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12364
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18016
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMX1B_KO_GDS3320_57_mouse_embryonic (e11.5) proximal hindlimb bud tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4645
hsa-miR-4419a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11184_KO_Jmjd1c_SRP239229	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.3869
PTCD3	Pathway Commons Protein-Protein Interactions	1.0	null
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920731
CYP24A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00638595
MRPL16	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPCL1	Pathway Commons Protein-Protein Interactions	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870539
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRM1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35348
BRD-K78867378_mw-A1-12_SNGM_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TRMT10C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K59130783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19426
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03077
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
20559987-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Mitochondrial translation	Reactome Pathways 2024	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47069
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4136
cellular component disassembly	GO Biological Process Annotations 2015	1.0	null
ATP5F1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PANC-08-13	GDSC Cell Line Gene Expression Profiles	1.0	1.44253
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMPCA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15291
BRD-K54931539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70713
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.54543
rectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62303
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71040831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13991
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41989
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02959126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38241
rostral secondary prosencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10603
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
15757864-Table5b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897336
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mitochondrial translation termination	Reactome Pathways 2014	1.0	null
BRD-K21124684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69838
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139966_1_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25576
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NME4	Pathway Commons Protein-Protein Interactions	1.0	null
BD-96-HO33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.492289
BRD-K36204977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0687
BRD-K53291208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54025
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62S-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AARS2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K05329107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07917
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9555
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
talampicillin-2954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93717
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05104
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04642
Degenerative Polyarthritis	DisGeNET Gene-Disease Associations	1.0	null
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.806446
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77106
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.565126
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845043
BRD-K96987864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13301
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8622
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37758
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.465335
NCOA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00460249
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43687
CRCGN015_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07933
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27731
BRD-K49669041_BX-912_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.519935
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1091
egg yolk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275444
GM2345	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.939254
GSE137144_3_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13546
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS11	Pathway Commons Protein-Protein Interactions	1.0	null
EVSA-T	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.28161
Perturb_10781_KO_Ahr_SRP326814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.40735
KDM6A-18722178-U937_AND_SAOS2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
ZFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52104
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.725274
Acute Myeloid Leukemia_LAML_TCGA-AB-2830-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE249893_1_v_0_tfam_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.79151
Leaf base	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27073
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.877383
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.547419
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.88974
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.13099
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222877
BRD-K50712773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34961
TIMELESS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12313
MRPL15	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6018
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_7_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20243
A-Vietnam-1203-2004(H5N1)_2day-IDO1KO_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.30747
GTEX-S7SF-1026-SM-4AD4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899768
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9524
17660535-TableS4b	GeneSigDB Published Gene Signatures	1.0	null
PMC6412103-mmc1.docx-5-M00695_ETF_P_8_350E-5_N_428_31_5_1_TEAD2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87482
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861609
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8142
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00428
GSE228181_2_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.251366
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K26826253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02613
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07086
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8593586-mmc2.xlsx-LIN28A_interactome-Unnamed_1_LIN28A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12234789-41467_2025_61560_MOESM3_ESM.xlsx-Supplementary_data_1-Only_YY1_IP-MS_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04142
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396087
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827143
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.677
BRD-K30022119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1761
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053772
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.864247
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.997613
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCMV_24Hour-anti_EGFR_treatment_20173022_GSE17948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.10725
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0863
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74171
CAD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
Lung squamous cell carcinoma_LUSC_TCGA-66-2781-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50103
CD7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00458724
hsa-miR-1266	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.40961
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.943815
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZB-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8305C_THYROID	CCLE Cell Line Proteomics	1.0	3.02044
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.940592
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
431_AQR_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.4361
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22534
Inflammation	CTD Gene-Disease Associations	1.0	1.78052
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958129
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJA3	Pathway Commons Protein-Protein Interactions	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
MRPL11	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL55	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_17440_Mut_Akt_SRP366791	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.13515
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1754
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCABER	CCLE Cell Line Gene CNV Profiles	1.0	1.7772
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21798
SPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00333955
GSE244710_1_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.078132
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
DHX30	Pathway Commons Protein-Protein Interactions	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.01589
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.601
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23771
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838162
GTEX-XUZC-0526-SM-4BOPF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878525
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.380045
Perturb_6859_KD_PUM1/PUM2_SRP287793	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.78664
TIMM10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148269,GSE148273_0_v_1_arid4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A34891365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39063
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045704
BRD-K14987634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66698
PMC5735185-41467_2017_1200_MOESM4_ESM.xlsx-Table_S1-Choi_et_al_2016_DUX4_up-regulated_targets_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.45607
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.887995
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.70031
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924455
Bladder Urothelial Carcinoma_BLCA_TCGA-R3-A69X-01A-22R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCNN1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507394
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-SOX2_partners-SOX2_known_protein_partners_according_to_BioGrid_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62894
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16664
HES-3	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.86392
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.28088
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_3_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
cotton fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.733912
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.4612
CA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00447992
TAF7	ENCODE Transcription Factor Targets	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25248
AIFM1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99521908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08673
Perturb_4316_KO_Ror2_SRP292420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.80234
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
Mitochondrial translation elongation	Reactome Pathways 2024	1.0	null
RNMTL1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K33400588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1714
imatinib_homo sapiens_gpl96_gds3046	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280747
BRD-K05068331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01259
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2284_OE_TLX_SRP358206	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.74093
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.89653
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.563287
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40297
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08175
CRCGN017_MCF10A.WT.HP_24H:B16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3605
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-36-VA24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.732413
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10117
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895103
GSE230174_0_v_1_dagla_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34034
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01978082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15324
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53471
BRD-K13301506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22677
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064644
YME1L1	Pathway Commons Protein-Protein Interactions	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976969
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05632
Neoplasms	CTD Gene-Disease Associations	1.0	1.71111
GSE211128_9_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTNNB1	ChEA Transcription Factor Targets	1.0	null
pain disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.1936
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.975209
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BB-93-VT73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231622
hsa-miR-3942-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934472
colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	0.881965
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62747
OCIAML2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0118
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-0.899254
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055247
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16872
CRCGN015_MCF10A.WT.HP_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27123
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139966_5_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80333
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2868
mitochondrial gene expression	GO Biological Process Annotations 2023	1.0	null
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69529
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_0Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.684441
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58201
proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.236
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907752
ovarian dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.211934
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12225
polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.09957
BRD-K21910317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76831
trans-Golgi network transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
BRD-K53647637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88319
SRF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrion organization	GO Biological Process Annotations 2015	1.0	null
OB-20-LP90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21729
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81318113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58054
KAT2B	ENCODE Transcription Factor Targets	1.0	null
Leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
SF539	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35562
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.72679
BRD-K78106941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3742
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933098
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.80894
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81881801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04736
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77819
endocrine organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058741
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_2_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06208
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PUS1	Pathway Commons Protein-Protein Interactions	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07026
protein binding	GO Molecular Function Annotations 2015	1.0	null
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17624
GSE126762_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BB-32-IZ10_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357114
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31981
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32040515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53922
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.44327
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.16799
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.58983
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5415
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61V-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
10549_ZNF681_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.644355
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12149
T47D	CCLE Cell Line Gene Expression Profiles	1.0	1.71683
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ribosomal protein L49/IMG2	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K83242582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14144
mediodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18743
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95542
CHD1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_13018_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.5229
SPPL2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.007093
Lymph node carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
r5 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01015
Perturb_10652_KD_Syncrip_SRP065017	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.69364
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5769
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.912043
infection	GAD High Level Gene-Disease Associations	1.0	0.293278
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19115
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.93209
EOMES	ChEA Transcription Factor Targets	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00625
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03078
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS-123	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.66641
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8944
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.72509
Multiple synapse bouton, contacting single dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.287
hsa-miR-1909	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JD-62-HR05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201412
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87907
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.091508
PMC11324510-41587_2023_1949_MOESM3_ESM.xlsx-Supplementary_Table6-Supplementary_Table_6_TP53_pathway_genes_list_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3833
r4 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35412
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16193
PDCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42721
GSE205540_2_v_0_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13441
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2614
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960535
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
small-subunit processome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.35748
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26423
SIN3A	ENCODE Transcription Factor Targets	1.0	null
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250301
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445201
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SP-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.71105
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.984821
MYC-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.55424
Mediodorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39204
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5281_KO_Ddx6_SRP137728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.22513
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K72213294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33476
GSE174735_2_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Colonic adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A.TP53.M_24H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31994
BRD-K74522958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1835
CRCGN017_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1214
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41486
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.765
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26542
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acute kidney tubular necrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.172544
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02095
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29788
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.13473
LIVF001-016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8664
NRF1	ENCODE Transcription Factor Targets	1.0	null
Superior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.73978
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.10172
Perturb_5282_KO_Ddx6_SRP137728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.62613
body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216933
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07396820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23755
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.53431
9454_TXNIP_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.654402
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.47012
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63058274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97615
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NDUFS2	Pathway Commons Protein-Protein Interactions	1.0	null
Bacterial Infection_Peripheral blood mononuclear cell_GSE3026	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.59944
communicating hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.418768
HCV JFH-1_24Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.95599
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76675
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.5844
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.76136
SREBP2-21459322-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10411
CEBPB_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_CNOT3_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2_01_349	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58745
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31428
HTT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01892
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5655
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02162
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-10.161
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
METTL17	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867647
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1437	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45446
DD-71-LY65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.741681
MRPL41	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A12725272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01146
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SA-32-CC58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413996
9478_UBA1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.648868
ribosome	GO Cellular Component Annotations 2015	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25854
VCAP	CCLE Cell Line Gene Expression Profiles	1.0	2.19182
RNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04774
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00408
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4565
GSE182680,GSE182683_7_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189941_1_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
EGFR_drugactivation_20_GDS2146	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.98636
BRD-K26383086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01806
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27447
BRD-K12612468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11625
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042287
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165548_2_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
CREB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45803
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBP1-19666523-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K08199068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22285
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6484770-41388_2018_602_MOESM5_ESM.xlsx-down_P53_vs_con-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K08262651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26819
FOXA1	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36111
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FCGR1BP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00469783
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065573
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K98938484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07162
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883562
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
functioning pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.119707
GSE128333_4_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51269
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16601
acute kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.135736
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
MRPL9	Pathway Commons Protein-Protein Interactions	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056223
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_down_VENN-1175_elements_included_exclusively_in_HIF1_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-376c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GA-87-BR97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260595
large ribosomal subunit	GO Cellular Component Annotations 2015	1.0	null
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mitochondrial inner membrane	GO Cellular Component Annotations 2025	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.647353
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3333
NOTCH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559816
GSE226584,GSE226589_3_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07232
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08263
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2769-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.21891
BRD-K07567566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0914
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4717_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
KLE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1622
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16589_KO_Mx_SRP133673	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.08804
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558117
MF-11-EW49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243875
SNU423_LIVER	CCLE Cell Line Proteomics	1.0	2.96214
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6286
BRD-K08241590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06117
LIVF001-002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18307
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67927
sulfanitran	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79961
BA-95-YU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3885
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280265
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39866321_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56156
PPARG-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K60363992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49765
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.01381
DC-23-UM36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332714
H3K36me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K20398543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.523
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-A59682351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61987
NFYA	ENCODE Transcription Factor Targets	1.0	null
BA-84-TD72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.454197
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58005
PMC6440742-elife-43627-supp4.xlsx-NFE2L2_ChIP-HeLa_ChIP2_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.858616
YY1-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
eyelid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.213283
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251734
BRD-K24396733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38031
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.826495
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A16827030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61004
AD-09-MD49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436819
conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354826
ornithine carbamoyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.565666
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13595
Perturb_12172_KO_CBFB_SRP159005	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.70902
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26597
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32454
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78409
bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.09209
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01015
Mitochondrial translation elongation	Reactome Pathways 2014	1.0	null
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938742
hsa-miR-4518	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65629
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.27279
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05474
phenindione-1718	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61851
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K90052868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06878
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GAREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00885
Memory Disorders	CTD Gene-Disease Associations	1.0	1.08797
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10633
MRPL38	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A76904477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21001
Sarcoma_SARC_TCGA-MJ-A68H-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
early-onset vitamin B6-dependent epilepsy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AC-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA6_01_247	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59925
H3K36me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL19	Pathway Commons Protein-Protein Interactions	1.0	null
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.44621
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86965
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10961_KO_Apom_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.66015
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972617
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Mitochondrial matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22772
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95311
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6579
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21999
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YARS2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_10128_KD_eHDAC6_SRP090317	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.29985
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838162
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58066
u698	HPA Cell Line Gene Expression Profiles	1.0	1.25141
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47698
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.958762
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.260184
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076952
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
Vitelline membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71903
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71191
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10501
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12472
BRD-K48727830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08653
BRD-K32131036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42223
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
NRF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_10763_KO_Ripk3_SRP370632	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.46668
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.100524
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63622
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.84196
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
mitochondrial translational initiation	GO Biological Process Annotations 2015	1.0	null
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_POU5F1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE231891_1_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04142
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IB-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944602
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49814
GSE133927_1_v_3_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.99597
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17898
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27883
organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040759
BRD-K38750802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05045
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15093
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838162
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854314
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL47	Pathway Commons Protein-Protein Interactions	1.0	null
FOXP1	ChEA Transcription Factor Targets	1.0	null
SIN3A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-0.805704
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16117
Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40334
PB-09-OE00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309157
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.720538
osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.13628
Hemopneumothorax	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.809
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7619
BRD-K19168437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60948
Perturb_3754_KD_RNF40_ERP110773	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.575
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2136
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71148
ATF3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24565
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38532
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041418
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.818201
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT29	CCLE Cell Line Gene Expression Profiles	1.0	1.38605
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11337
BRD-K50710005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51565
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18559
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847255
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RH41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35164
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61355
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.8545
BRD-A99402294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57704
Perturb_14809_OE_Ldah_SRP282425	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.0969
BRD-K11589884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60522
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
sputum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.324605
Perturb_11424_KD_KIF4A_SRP324259	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.14625
GSE255680_2_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77701
BRD-K95937143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20301
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07798
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485156
translational termination	GO Biological Process Annotations 2015	1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Middle frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
PF-59-CY33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553858
FB-32-PY27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215371
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835242
hsa-miR-4780	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NALM-6	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.1786
BRD-K60296400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48967
binding	GO Molecular Function Annotations 2015	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8283158-mmc2.xlsx-TCF4_NPC-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01581
GSE202017,GSE202018_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_7297_KO_CD34_SRP156691	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.55682
DDX28	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68408
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03622
Prostate adenocarcinoma_PRAD_TCGA-G9-7521-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H727	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.16021
OXA1L	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47915
BRD-K62184784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19408
BRD-K78559095_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15163
UACC893	CCLE Cell Line Gene Expression Profiles	1.0	1.54518
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Retigabine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82701
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2723
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969451
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58356
protein complex involved in cell adhesion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.076385
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.324605
GRM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00602478
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01057
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17468
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.935997
YY1	ChEA Transcription Factor Targets	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337199
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35717699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64095
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24266
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77302
KYSE450	CCLE Cell Line Gene Expression Profiles	1.0	1.56907
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NDUFAF3	Pathway Commons Protein-Protein Interactions	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.34467
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884873
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12084
EZH2	ENCODE Transcription Factor Targets	1.0	null
PANC1	BioGPS Cell Line Gene Expression Profiles	1.0	1.01353
PMC8283158-mmc2.xlsx-TCF4_Glut-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.56166
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33225
hsa-miR-3173-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NANOG	ENCODE Transcription Factor Targets	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7004
EVSAT	CCLE Cell Line Gene Expression Profiles	1.0	1.34789
Perturb_14840_KD_GCM1_SRP358680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.8161
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5771
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
M14 cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.30516
mitochondrial membrane	GO Cellular Component Annotations 2025	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331927
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S2-HSF1_CanSig_Genes-HSF1-CanSig_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.748753
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.066873
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20514
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902797
19843711-TableS1	GeneSigDB Published Gene Signatures	1.0	null
fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.559652
BRD-K60024977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2394
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833667
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.596521
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Osteoporosis	DisGeNET Gene-Disease Associations	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05586
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48499
Stoma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927572
organelle	GO Cellular Component Annotations 2015	1.0	null
Perturb_10149_KO_FOXK1_SRP251223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.6359
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065331
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
GTEX-O5YV-1626-SM-2YUNJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41906
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320137
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841759
BRD-K92581247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02344
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.54548
CB-55-AK76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.344919
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41914
USF1	ENCODE Transcription Factor Targets	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044923
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16313
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.05107
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03328
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.76424
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42671
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K52101275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59648
organelle inner membrane	GO Cellular Component Annotations 2023	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88K-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	1.0	2.07763
Combined oxidative phosphorylation deficiency 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17667
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11905
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66685
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23914
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07622
MRPS18B	Pathway Commons Protein-Protein Interactions	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Corticospinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219485
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VPC23019	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LD-69-ZV56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367177
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH2009_LUNG	CCLE Cell Line Proteomics	1.0	3.9631
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03602135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08394
TH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050243
BRD-K99964838_bosutinib_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869618
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
HDAC6_KO_GDS4375_372_mouse_CD4+CD25+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAJI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9668_Mut_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.56774
AF-67-LZ82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225117
Perturb_7927_KD_ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.61218
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98953
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.970082
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45182
BRD-A97608543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32472
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27355
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34955
cellular protein complex disassembly	GO Biological Process Annotations 2015	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.46995
BRD-K56987347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01492
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965203
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995463
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
fibrous dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.361133
BRD-K08043579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3892
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2056
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28214
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17891
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56209
SCC-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.978604
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03347
BRD-K01762107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14107
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42564
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045888
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.90751
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16958
RPS8	Pathway Commons Protein-Protein Interactions	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15757
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21565
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.88974
irf1_17409403_nih3t3_gof_mouse_gpl81_gds2752	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.88002
epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879002
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.612011
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.531484
amnestic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.194865
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904415
Perturb_10965_KO_Blk_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.24003
PMC12822963-pone.0339296.s005.xlsx-Sheet1-HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906442
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11651
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63622
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02976
horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.291008
BRD-K01162126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14977
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-1.0671
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10838
SPRY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1559
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1	ChEA Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.959744
MRPL17	Pathway Commons Protein-Protein Interactions	1.0	null
colonic adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K22193148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15078
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHCHD2P9	Pathway Commons Protein-Protein Interactions	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K45378289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33226
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00498
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.961552
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10423
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
T173	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57063
Macular degeneration_Fibroblast_GSE1719	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.65458
translational initiation	GO Biological Process Annotations 2015	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_6_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.73977
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4304
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.126
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38532
cell part	GO Cellular Component Annotations 2015	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BA-59-EN38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382856
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.226331
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35912
ALG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58004
BC-32-DI69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222395
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_CHD1_19587682	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K02946901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33188
coccidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.121018
PMC11165579-pr4c00112_si_001.pdf-58-THYN1_THYN1	Rummagene Transcription Factor Associations 2026	1.0	null
Colonic cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06905
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory chain complex iii	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.530028
Plasma membrane respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_77_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045868
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80139
GSE193993_4_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06032
RPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37098
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02242
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.86999
Carcinoma	CTD Gene-Disease Associations	1.0	1.10942
RPMI7951_SKIN	CCLE Cell Line Proteomics	1.0	3.17347
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73296
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34542210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26209
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-JV-A5VE-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A20248179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43733
BRD-K20026212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95676
BRD-K47337578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87196
Perturb_10131_KD_GATA1_SRP090317	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.02346
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Melanoma	CTD Gene-Disease Associations	1.0	2.88009
Plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900354
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
9601_UPF2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.01221
BRD-K13320013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31357
BRD-A37796306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78855
GTEX-S3XE-0126-SM-4AD4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57546
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48673
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LN235	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50227
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80088
GSE206516,GSE206518_0_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BOLA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09424
PAX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K31269097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09677
glossopharyngeal neuralgia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.14305
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1278_KO_Ptpn2_SRP108032	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.9177
H3-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0332
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2582
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Y-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84174
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.83474
Heart Failure	CTD Gene-Disease Associations	1.0	1.15865
GLDC	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K12132610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41769
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
translation	GO Biological Process Annotations 2025	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.519472
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23539
hsa-miR-4436b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.56121
GSE110178_5_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03275
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14999
BRD-K31898235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67532
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33354
MRPS16	Pathway Commons Protein-Protein Interactions	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8708
Perturb_11053_Mut_Lmna_SRP309326	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.2058
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14456
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46607226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16259
Perturb_7229_KD_CNOT1_SRP285534	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.99548
PRF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00802316
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61536
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.926566
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-361	GDSC Cell Line Gene Expression Profiles	1.0	1.43124
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80246
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31003
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08192
BRD-K03370561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00877
GTEX-VJYA-0526-SM-4KL1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4825
GA-04-JM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.757819
GM133	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.949425
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328214
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950376
BRD-K72439355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9666
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08076
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048602
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.988849
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827557
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03106
FOXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07244
hsa-miR-548x	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2949
Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054508
SKMEL2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.80091
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.893869
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61368
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178532_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2813
demyelinating polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.222136
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE255680_1_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MGST3	Pathway Commons Protein-Protein Interactions	1.0	null
DACH1-20351289-MDA-MB-231-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K06729289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37106
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
essential tremor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.347511
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36111
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22535
ATF3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.56459
hsa-miR-548am	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
BRD-K45361857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32195
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04671
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6644
BRD-K08142337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95805
HCC-202	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.21823
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MRPL27	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5921
MRPS9	Pathway Commons Protein-Protein Interactions	1.0	null
EC-89-AJ93_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350627
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02583
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAND1	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-A48L-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K93747373_HG-5-113-01_MCF10A_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MRRF	Pathway Commons Protein-Protein Interactions	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.943183
OCI-AML2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.95588
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76731
BTNL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056084
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.601
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1437	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42052
Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.916336
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04535
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08527
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861423
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205349
GTEX-XBED-0926-SM-48TCE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854114
SLC25A10	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1285	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60398
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
SF539	GDSC Cell Line Gene Expression Profiles	-1.0	-1.60531
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29X-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A63759745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23076
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-3398-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS2	Pathway Commons Protein-Protein Interactions	1.0	null
PMPCB	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05088
BRD-K72707702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38994
ATF3	ENCODE Transcription Factor Targets	1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48540267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50066
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GRM6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496369
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3849
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2864
EP300	ENCODE Transcription Factor Targets	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25739
BRD-K30823221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63683
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.33547
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
IMMT	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_5139_KD_Dax1/Dux_SRP311833	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.32985
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.881739
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976849
15474998-tableS1c	GeneSigDB Published Gene Signatures	1.0	null
PMC8384902-mmc2.xlsx-3_ASCL1_high_subtype-Gene_Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02057
NR2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22963
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827183
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848983
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3749_KD_NORAD_SRP149071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.97727
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64402
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67796
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
colonic cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.976552
ATF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01494
BRD-K68314790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63378
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52606
pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PTCD1	Pathway Commons Protein-Protein Interactions	1.0	null
KDM6A	ChEA Transcription Factor Targets	1.0	null
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050664
OF-05-CB18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.846827
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999329
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301288
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24418561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36776
Neuronal ceroid lipofuscinosis 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VARS2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MELHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54003
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A77488069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32634
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55629
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.63793
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GSE112761,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary ovarian insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
VA-ES-BJ	GDSC Cell Line Gene Expression Profiles	-1.0	-1.81013
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MC-51-BT07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218432
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872428
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6781
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10114
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9601_UPF2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.937078
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64576
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920027
S-isopropylisothiourea	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18629
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.03617
PMC4416014-pone.0125585.s010.xls-d_-BNC_network-Interactor_B_BNC1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62202988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01009
DOT1L_DELETION_GDS4295_427_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 5 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6556_KO_Pfkfb4_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.99764
SMAD3	ChEA Transcription Factor Targets	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0021
Pituitary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.8913
COLO-678	GDSC Cell Line Gene Expression Profiles	1.0	1.80773
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NDUFS1	Pathway Commons Protein-Protein Interactions	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08192
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52225720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61102
Weight Loss	CTD Gene-Disease Associations	1.0	1.65181
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD-16-KY17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334651
SARS-CoV MA15_Day1-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.915614
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14746
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.850738
BRD-K74598339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02227
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924642
ATAD3A	Pathway Commons Protein-Protein Interactions	1.0	null
MCAT	Pathway Commons Protein-Protein Interactions	1.0	null
Organelle biogenesis and maintenance	Reactome Pathways 2014	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13603_KD_KLF4_SRP221596	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.24076
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
Electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
ZNF263	ENCODE Transcription Factor Targets	1.0	null
Perturb_14068_KD_ALKBH5_SRP247667	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.50646
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11109217-41420_2024_2017_MOESM3_ESM.xlsx-Fig_4H_TAF2-bound_genes-Tag_dentsity_of_TBP_ChIP-seq_signal_for_TAF2-bound_genes_in_Fig_4H_TBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null