association dataset threshold value standardized value H4K5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K86988191 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38012 15656903-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null BLTP3A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00508896 CTCF_GM12866_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null t61-colon_consensus MoTrPAC Rat Endurance Exercise Training 1.0 2.83011 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2045 CTCF_foreskin fibroblast_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K05804044_AZ-628_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.838175 RPL7A Pathway Commons Protein-Protein Interactions 1.0 null HIST1H1E Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QCQG-0008-SM-48U2G GTEx Tissue Sample Gene Expression Profiles 1.0 2.11637 Perturb_6755_KO_UPF3A/UPF3B_SRP327782 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.1792 GTEX-Q2AG-1026-SM-33HBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.86286 Perturb_4836_KO_Chd8_SRP306703 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.40988 GTEX-U4B1-0008-SM-4DXUW GTEx Tissue Sample Gene Expression Profiles 1.0 1.49876 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.96194 PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12 Rummagene Transcription Factor Associations 2026 1.0 null HIST1H1B Pathway Commons Protein-Protein Interactions 1.0 null DDX28 Pathway Commons Protein-Protein Interactions 1.0 null H3K14ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CEBPD_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null biperiden-2460 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null r5 part of the oral Sp5 subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.24805 motor nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.85874 NCIH1581 CCLE Cell Line Gene CNV Profiles -1.0 -1.65504 BRD-K19381111 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.24626 ZNF276 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00431509 bethanechol-2975 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38737 FOS_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE178255_3_v_6_tlr4_mouse RummaGEO Gene Perturbation Signatures -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02756 FAM78A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11864 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null BRD-K40612106 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.44335 BRD-K90230495 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25608 H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4525_KO_Chaf1a_ERP006640 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.88923 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_K562_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.09229 Perturb_6900_KO_FOXC1_SRP185801 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ3S-0008-SM-4GIDZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.14777 GSE201042_6_v_1_ptpmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SP1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM15510_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K08618283 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10526 RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13242_OE_Med24_SRP201000 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.4726 HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15875_KO_Atoh1_SRP002802 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.37867 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.830429 mantle zone of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06434 GLTSCR2 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null imatinib_homo sapiens_gpl96_gds3047 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hsa-miR-499a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 REST_Panc1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62926 intermediate stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10677 GATA2-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.64357 BRD-K06492501 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33737 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null JAK1 Kinase Library Tyrosine Kinome Atlas 1.0 95.52 H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null single-organism biosynthetic process GO Biological Process Annotations 2015 1.0 null sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.732596 BRD-A79768653_sirolimus_HT29_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ZNF384_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MS-0011-R8a-SM-2YUMK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23926 CREB1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20894 pancreas TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 imatinib_homo sapiens_gpl96_gds3044 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.83739 hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057935 BRD-K80210288 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13616 guanadrel-7396 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K23793049 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2087 small ribosomal subunit GO Cellular Component Annotations 2015 1.0 null Urinary Bladder Neoplasms CTD Gene-Disease Associations 1.0 1.17662 STAT3 ENCODE Transcription Factor Targets 1.0 null facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00997 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF Rummagene Transcription Factor Associations 2026 1.0 null CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K82397896 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53363 GSTZ1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00443967 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2182 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null kidney_d HPA Tissue Sample Gene Expression Profiles 1.0 0.997847 SKOV3 BioGPS Cell Line Gene Expression Profiles -1.0 -1.63066 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055809 alimentary canal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_1155_KO_Max_SRP150708 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.6383 VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06949 Perturb_4864_KD_SON_ERP003259 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GTEX-QDT8-0926-SM-32PL2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.842484 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null BRD-K31666797 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05806 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2279 CCLE Cell Line Gene Expression Profiles 1.0 1.59803 PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-DESeq_MSC_vs_fibroblast_MSC Rummagene Transcription Factor Associations 2026 1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 SARS-CoV_12Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.60707 GTEX-T6MO-0008-SM-4DM6T GTEx Tissue Sample Gene Expression Profiles 1.0 1.65046 CTCF_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null heterogeneous GeneRIF Biological Term Annotations 1.0 null substantia nigra reticulata, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00909 COQ7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33487 ATM_knockdown_18_GDS1852 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.01694 KLF4-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF_GM12869_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB-20513432-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K79me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UTP23 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.961375 GTEX-RU72-0726-SM-46MUW GTEx Tissue Sample Gene Expression Profiles 1.0 1.01205 RUNX2-24655370-MC3T3E1-MOUSE-BONE ChEA Transcription Factor Targets 2022 1.0 null Superior colliculus, motor related, intermediate gray layer, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17337 POU2F2_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1205 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 SP2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE198165,GSE198166_8_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null DDX47 Pathway Commons Protein-Protein Interactions 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null nystatin-2500 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NCIH211 CCLE Cell Line Gene Expression Profiles 1.0 1.39585 BRD-K20560768 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44105 OVISE CCLE Cell Line Gene Expression Profiles 1.0 1.82634 GTEX-WEY5-0001-SM-3P61Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.963514 GSE112860_9_v_8_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null LS 174T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02212 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K04092807 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6304 USF1_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CXCR2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00497016 CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Goblet cell_Intestinal crypt_Mouse CellMarker Gene-Cell Type Associations 1.0 null boxes GeneRIF Biological Term Annotations 1.0 null BRD-K96547094 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.09839 posteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46109 H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K07928699 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4237 H3K79me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K53104784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03023 ELF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TMZS-0001-SM-3P61Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.13357 Perturb_4858_KD_SON_ERP003259 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 mammillary area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32907 BRD-K87358945 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10417 etamivan-7021 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K69505608 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08525 H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ETS1-21867929-TH2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE153137,GSE153140_2_v_0_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null T98G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01848 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC3153 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.649962 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14001_OE_DNMT3L_SRP279231 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.6655 H3K79me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1569 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.4004 BRD-K51967704_S1175_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Carcinoma, Squamous Cell CTD Gene-Disease Associations 1.0 1.10562 GTEX-TSE9-0011-R11A-SM-3DB7N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26207 BRD-K93990956 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24872 BRD-K77181307 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24594 SIN3A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null GTEX-WFG8-0008-SM-4LVN6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.40451 GTEX-X88G-0004-SM-47JZ6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19316 GSE118794_5_v_4_zmynd8_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_8830_KD_MYEOV_SRP313537 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42537 SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCL3 ENCODE Transcription Factor Targets 1.0 null DARS Pathway Commons Protein-Protein Interactions 1.0 null L755507 DeepCoverMOA Drug Mechanisms of Action -1.0 -0.26 BRD-K30221348 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17895 CPSF2 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K41311678 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37958 WT1-25993318-PODOCYTE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null macromolecular complex disassembly GO Biological Process Annotations 2015 1.0 null LAMA5 Pathway Commons Protein-Protein Interactions 1.0 null TAF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2718_KD_BRD_SRP115100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.05224 HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23388 H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE203308_14_v_0_brf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_8918_KD_ARID1A_SRP256204 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.33755 Perturb_13827_KO_Pten_SRP302970 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.19337 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0655 NFYA_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.42494 Perturb_9136_KD_EZH2_SRP090707 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.90329 BRD-K95138506_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PMAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14526 CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PU-27001747-CHIP-SEQ-BMDM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BRD-K44307624 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.03003 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F4_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS1 ENCODE Transcription Factor Targets 1.0 null PRKDC Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XV7Q-2126-SM-4BRVX GTEx Tissue Sample Gene Expression Profiles 1.0 1.28565 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.926898 BRD-A75409952_wortmannin_SKM1_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-PWOO-0008-SM-48TDU GTEx Tissue Sample Gene Expression Profiles 1.0 1.96673 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K60848736 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13986 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.09662 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_7875_KD_H2A.Z.2_SRP259021 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.32923 GTPBP10 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SJ-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE109913_1_v_2_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 SIN3A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K77832645 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24804 CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K05653692_DL-PDMP_PC3_24.0_h_64.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null cerebellar cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.00284 GTEX-QMR6-0008-SM-447AV GTEx Tissue Sample Gene Expression Profiles 1.0 1.62285 PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-Hela_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K04706894 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24516 H3K36me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE87144_3_v_1_rorc_mouse RummaGEO Gene Perturbation Signatures -1.0 null heart_6b HPA Tissue Sample Gene Expression Profiles 1.0 1.13513 GTF3C5 Pathway Commons Protein-Protein Interactions 1.0 null PCBP1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K36153907_KUC103885 KUC103885N_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16665 GTEX-N7MS-1626-SM-3LK5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.01744 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K92794990 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50315 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ATRIP LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00559147 kidney HPA Tissue Gene Expression Profiles 1.0 1.10609 POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TEAD4_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF1 ENCODE Transcription Factor Targets 1.0 null Perturb_7388_KO|KD_UPF3B|UPF3A_ERP130413 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.238 decreased exploration in new environment IMPC Knockout Mouse Phenotypes 1.0 null Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20856 CTCF_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.164571 HEK 293 T-rex BioGPS Cell Line Gene Expression Profiles 1.0 1.237 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.61454 16-phenyltetranorprostaglandin E2-7509 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM160 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.62422 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.22312 KP-N-YS COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 primary metabolic process GO Biological Process Annotations 2015 1.0 null dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.898568 BRD-K35424586_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MRPL40 Pathway Commons Protein-Protein Interactions 1.0 null KAT2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MC-1010 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K42918627_GSK-2126458_SKBR3_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K46373671_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NCI-H740 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.15602 GTEX-WFG8-1326-SM-4LVN3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03699 RH-1 GDSC Cell Line Gene Expression Profiles 1.0 2.10985 GTEX-TML8-1326-SM-4DXTO GTEx Tissue Sample Gene Expression Profiles 1.0 0.94578 GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -2.55333 H3K27ac_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RS4-11 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.2172 mitochondrial inner membrane GO Cellular Component Annotations 2015 1.0 null intermediate pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62581 troglitazone-1173 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TCF12_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.79954 BRD-K52424224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16725 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14615 BRD-K69932463_AZD8055_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CPT1A Pathway Commons Protein-Protein Interactions 1.0 null CTCF-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-TSE9-0726-SM-3DB8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26641 trichostatin A-3114 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SUP-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE224969,GSE224971_0_v_7_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null INSM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29088 POLR2A ENCODE Transcription Factor Targets 1.0 null CHD1-19587682-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BRD-K35616138 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43677 GSE155852_0_v_1_apigenin_mouse RummaGEO Drug Perturbation Signatures 1.0 null SIX5_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRPS17 Pathway Commons Protein-Protein Interactions 1.0 null SRP14 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K08307026_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null 18631401-TableS3 GeneSigDB Published Gene Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2771-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K74710236_VU0410183-2_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_15091_KO_Nrf2_SRP121279 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.74941 BRD-K69328504_L-690,488_SW948_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null promethazine-3100 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NELFB Pathway Commons Protein-Protein Interactions 1.0 null SNU719 CCLE Cell Line Gene CNV Profiles 1.0 1.33116 GTEX-TML8-0008-SM-4DXUI GTEx Tissue Sample Gene Expression Profiles 1.0 1.59929 H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Mitochondrial translation Reactome Pathways 2014 1.0 null COLO829_SKIN CCLE Cell Line Proteomics 1.0 3.61108 Perturb_14589_KI_LAMC2_ERP136718 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.49046 Perturb_1201_KO_Sp1_SRP302435 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fulvestrant_homo sapiens_gpl570_gse22533 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung adenocarcinoma_LUAD_TCGA-62-A471-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null zonal layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14395 BRD-K92991072_PAC 1_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3330_KO_miR27_SRP092642 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.5849 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4838_OE_Gfi1_SRP220284 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.38023 MED30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51983 NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71761 NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.47136 sirolimus_mus musculus_gpl1261_gse5332 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null retina BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.27603 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16279 NFYB_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K26738018 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.09247 Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Epithalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06755 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.24488 gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 GTEX-RVPU-0011-R9A-SM-3NM8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67981 LCLC-97TM1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20677 TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12872_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13274_KO_Zbtb24_SRP198760 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -14.3346 GTEX-T6MN-0008-SM-4DM7H GTEx Tissue Sample Gene Expression Profiles 1.0 1.50905 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SP2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRPF19 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K31660953 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14376 epithelioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.272649 Carcinoma, Hepatocellular CTD Gene-Disease Associations 1.0 1.16833 SCX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36736 adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058641 BRD-K23112275 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33771 H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DAP3 Pathway Commons Protein-Protein Interactions 1.0 null MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.62815 GTEX-P4QS-1826-SM-2S1NI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.977222 BRD-A19248578_L5288-1MG_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Mitochondrial translation elongation Reactome Pathways 2014 1.0 null H3K79me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null organelle lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.551425 CNP Pathway Commons Protein-Protein Interactions 1.0 null BRD-K28059618 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.71505 r9 part of the lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63069 GTEX-SJXC-0005-SM-2XCE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889473 H3K27ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K51572611 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18304 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular part LOCATE Curated Protein Localization Annotations 1.0 null ELK1-22589737-MCF10A-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ZNF626 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00168 BRD-K67868012_PI-103_LNCAP_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Brain - Hippocampus GTEx Tissue Gene Expression Profiles 2023 1.0 1.83194 trim28_23493425_cd71pluster119plus_sorted_from_bone_marrow_lof_mouse_gpl6887_gse44063 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.276351 RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.898421 omeprazole-2467 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-XQ3S-1726-SM-4BOOD GTEx Tissue Sample Gene Expression Profiles 1.0 0.897804 Perturb_3651_KO_RIPK1_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.52399 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RTCB Pathway Commons Protein-Protein Interactions 1.0 null PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U8XE-0926-SM-3DB8V GTEx Tissue Sample Gene Expression Profiles 1.0 0.882011 BRD-K74710236_VU0410183-2_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K32879108 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49795 CRTC1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00641242 BRD-K65182930_NVP-AUY922_MCF10A_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K79090631_CGP-60474_A549_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null digestive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-K15833017 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19978 BCL3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4364_KD_Setdb1_SRP055819 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.38196 GTEX-XBEW-0002-SM-4AT5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.08279 BRD-K10882151_BO2 (inhibits RAD51)_PC3_24.0_h_40.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K00976973 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3693 CTCF_fibroblast of lung_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2824_KD_KMT9A_SRP154908 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.65673 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_medulloblastoma_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12012_KO_B2_Mm2_SRP374407 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.56849 Learning Disorders CTD Gene-Disease Associations 1.0 1.20295 PMC7825356-8844261.f3.docx-118-ZNF461_ZNF461 Rummagene Transcription Factor Associations 2026 1.0 null tacrolimus-378 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.893882 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VJWN-0126-SM-3GIK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881263 BRD-K07825644 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.76896 dyclonine-7022 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_545_KD_CT_SRP201842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.66992 dorsal part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7264 GTEX-WZTO-1326-SM-3NM8X GTEx Tissue Sample Gene Expression Profiles 1.0 1.02412 BRD-K19220233_JNK-9L_HME1_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP3-21729870-TREG-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CORL88 CCLE Cell Line Gene CNV Profiles 1.0 1.34549 BRD-K04358482 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21433 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K36170758 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30484 RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RUNX1 ChEA Transcription Factor Targets 1.0 null TOP1 Pathway Commons Protein-Protein Interactions 1.0 null mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14864 QARS Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPP1CA Pathway Commons Protein-Protein Interactions 1.0 null RPS27 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9311_KD_Trp53_SRP320074 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.39986 YBX1 Pathway Commons Protein-Protein Interactions 1.0 null lateral septal nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39783 BRD-K57184137 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.02315 RPA1 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7747_KD_CNOT1_SRP155278 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.02651 sirolimus-5980 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K56196992_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03839 LSM14A Pathway Commons Protein-Protein Interactions 1.0 null MYC_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null MET_knockout_252_GSE30651 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.48582 pparg_21068720_macrophage_c57bl6_lof_mouse_gpl1261_gds4370 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.180534 GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.81254 PATU8988T CCLE Cell Line Gene CNV Profiles 1.0 2.35169 BRD-K36763492 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.90314 BHLHE23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22641 BRD-K83972459_JWE-035_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_WI38_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null klf4_17017123_rko_gof_human_gpl96_gds1942 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 1.56776 EIF3B Pathway Commons Protein-Protein Interactions 1.0 null KCTD12 Pathway Commons Protein-Protein Interactions 1.0 null TAF1_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HN-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TASK1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WL46-0011-R9A-SM-3MJFP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.893568 PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-Q2AG-0011-R9A-SM-2HMJ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43689 H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null doxorubicin_homo sapiens_gpl570_gse46493 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCFL_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sensorineural hearing loss DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.494 GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.98984 BRD-K79090631_CGP-60474_A549_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NAA38 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K50140147_NVP-TAE684_HT29_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K31554491 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17113 H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K99545815_HY-10459_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RELA_GM18505_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HIST1H1A Pathway Commons Protein-Protein Interactions 1.0 null BRD-K25596713 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34108 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP63_01_330 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.58504 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14615 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2227 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 STRAP Pathway Commons Protein-Protein Interactions 1.0 null Perturb_4793_KD_Tex10_SRP056038 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCND1-20090754-RETINA-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K56778317 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38546 PMC7856198__F5 PFOCR Pathway Figure Associations 2024 1.0 null outer CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.896198 FEN1 Pathway Commons Protein-Protein Interactions 1.0 null intermediate stratum of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62225 CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37847 NOLC1 Pathway Commons Protein-Protein Interactions 1.0 null diclofenac-445 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PATU8988T CCLE Cell Line Gene Expression Profiles 1.0 2.633 BRD-K18621941 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06671 Perturb_12868_KD_EP400_SRP059494 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 G3BP1 Pathway Commons Protein-Protein Interactions 1.0 null MTDH Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WCDI-0008-SM-47JYE GTEx Tissue Sample Gene Expression Profiles 1.0 1.05172 RAD21_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K31325635 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47233 CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF7L2_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AGS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04914 H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K22668106 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71476 GTEX-Q2AI-0926-SM-48U1F GTEx Tissue Sample Gene Expression Profiles 1.0 0.915115 GTEX-VUSH-0004-SM-3P61T GTEx Tissue Sample Gene Expression Profiles 1.0 1.7773 Perturb_813_OE_TRIB3_SRP262247 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.15984 BRD-K28465224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49447 TCEANC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24465 cervix, uterine HPA Tissue Protein Expression Profiles -1.0 -1.44783 BRD-K99903568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38297 cellular component organization or biogenesis GO Biological Process Annotations 2015 1.0 null GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -3.20103 CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NMT1 Pathway Commons Protein-Protein Interactions 1.0 null translation at postsynapse SynGO Synaptic Gene Annotations 1.0 null H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LRIF1 Hub Proteins Protein-Protein Interactions 1.0 null H3K18ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC12289921-41467_2025_62099_MOESM4_ESM.xlsx-MI-2-80-Gene_Symbol_MITF Rummagene Transcription Factor Associations 2026 1.0 null MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF3C2 Pathway Commons Protein-Protein Interactions 1.0 null ZC3H15 Pathway Commons Protein-Protein Interactions 1.0 null H3K9ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08349 H3K4me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.76294 RPS12 Pathway Commons Protein-Protein Interactions 1.0 null NPRL2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00443819 PMC11151076-ADVS-11-2306486-s002.xlsx-TSPYL1_FOXA1_targets-DDB2_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K29178949 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07475 POLR2A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNRNPH2 Pathway Commons Protein-Protein Interactions 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null infection GAD High Level Gene-Disease Associations 1.0 0.293278 GM1600 BioGPS Cell Line Gene Expression Profiles -1.0 -1.07355 PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Table_S1_Lists_of_translational_targets_of_MYC_in_MYC_ON_vs_MYC_OFF_P493_cells_and_their_5_UTR_sequences_MYC Rummagene Transcription Factor Associations 2026 1.0 null FMR1 Pathway Commons Protein-Protein Interactions 1.0 null E2F1 ChEA Transcription Factor Targets 1.0 null nabumetone-5428 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MSH3 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9246_KO_Lin28b_SRP300815 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SJXC-0526-SM-2XCFG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12833 Perturb_12631_KD_SIRT5_SRP311327 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.61546 Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_5633_KD_BRD4_SRP142503 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.7709 Perturb_6169_KD_PROX1_SRP073100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.04716 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.86385 CTCF_A549_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZG-0001-SM-47JYF GTEx Tissue Sample Gene Expression Profiles 1.0 1.05082 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SC-19220-7060 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_5587_KO_NFKBIA_SRP149723 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.05302 stomach_3b HPA Tissue Sample Gene Expression Profiles 1.0 0.828328 GTF2F1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22364 BRD-K46014293 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27907 GSE225656_0_v_1_tsc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XYKS-0526-SM-4BRW2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.923883 POLR2A_GM18505_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02076 Perturb_12196_KD_ERCC5_SRP310546 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 BRD-K28269391 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83835 BRD-K19103068 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11092 Perturb_7169_KD_CD81_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.68966 H2BK5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null C14orf1 Pathway Commons Protein-Protein Interactions 1.0 null Autosomal dominant distal hereditary motor neuronopathy 5 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.135 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MTA3 ENCODE Transcription Factor Targets 1.0 null BRD-K47063692 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25872 Perturb_8915_KO_KDM1A2a_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.5638 Perturb_1154_KO_USP29_SRP329795 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.68567 POLRMT Pathway Commons Protein-Protein Interactions 1.0 null GSE199899_4_v_2_diethylnitrosamine_mouse RummaGEO Drug Perturbation Signatures -1.0 null intermediate stratum of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14471 HNRNPD Pathway Commons Protein-Protein Interactions 1.0 null Perturb_14797_KO_Ltf_SRP331832 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.31409 Lingula (I), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03769 GATA1_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.71618 DCST2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00650663 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-135b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 primary motor cortex (area M1, area 4)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.60569 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.841541 H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAR1 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17197 H3K4me1_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE193282_2_v_0_cd44_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K74289419 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13413 ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34331 DRD4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00518902 REST-19997604-NEURONS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QF-01A-21R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null LRIF1 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSMB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11661 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null XRCC6 Pathway Commons Protein-Protein Interactions 1.0 null CAND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11286 SNU46 CCLE Cell Line Gene CNV Profiles -1.0 -2.7022 GTEX-U3ZM-0008-SM-4DXTQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.72743 NCI-H661 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 gastrointestinal tract TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null interacts GeneRIF Biological Term Annotations 1.0 null mediodorsal nucleus of thalamus_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.887102 Perturb_3637_KO_BLVRB_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.45151 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Pericardial Effusion CTD Gene-Disease Associations 1.0 1.06188 POLR2A_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null 55S ribosome, mitochondrial CORUM Protein Complexes 1.0 null U2AF2 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K99210277 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02434 Anterior cingulate area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25493 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DCTN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21587 BRD-K14707716 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84971 H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mitochondrion COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.437356 CTNND1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K34720817 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25821 GTEX-PSDG-0926-SM-2I5FP GTEx Tissue Sample Gene Expression Profiles 1.0 1.12111 Perturb_7314_KO|KD_UPF3A_ERP130416 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.91779 BRD-K40175214_torin-1_MCF7_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ER-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.94768 t30-blood-rna_consensus MoTrPAC Rat Endurance Exercise Training 1.0 9.36915 GTEX-QV44-0008-SM-447AX GTEx Tissue Sample Gene Expression Profiles 1.0 1.32059 Perturb_8048_KD_METTl14_SRP167173 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.84464 ChIP_H3K36me3_18692474_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.64482 CENPM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13282 H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NOL3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00691297 AKAP1 Pathway Commons Protein-Protein Interactions 1.0 null POLR2AphosphoS5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE231648_4_v_2_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.950715 POLR2AphosphoS5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RELA_GM18951_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null arcuate nucleus of medulla, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05706 FXR1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K53619784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04685 GSE231648_4_v_5_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K02708799_GSK-1059615_HT29_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-S4UY-0426-SM-3K2AF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.90776 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fusidic acid-5353 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null preweaning lethality, complete penetrance MGI Mouse Phenotype Associations 2023 1.0 null GSE200673,GSE200691_1_v_0_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K62511698 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72 BRD-K62459624_T5212475_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null cytoplasmic translation GO Biological Process Annotations 2023 1.0 null H2BK12ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GHSR LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0057896 CTCF_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1299 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.82739 G141 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.0938 TMEM214 Pathway Commons Protein-Protein Interactions 1.0 null H4K20me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WOFM-1726-SM-3MJFA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47745 SIRT6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JW-0008-SM-4DM5X GTEx Tissue Sample Gene Expression Profiles 1.0 2.28281 BRD-K34254821 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33099 Perturb_6029_KD_KHDRBS3_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SEMA6C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02359 MYC-22102868-BL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.00881 MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55006 EP300_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02955 NCIH1092 CCLE Cell Line Gene Expression Profiles -1.0 -3.00868 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intestine TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K18181387 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08168 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.199659 H3K27ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K19220233_JNK-9L_HME1_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE201042_6_v_7_ptpmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNU-719 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05403 EIF4G1 Pathway Commons Protein-Protein Interactions 1.0 null sensorineural hearing loss DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.19359 BRD-K37940862_NCGC00185684-02_VCAP_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SP4 ENCODE Transcription Factor Targets 1.0 null GTEX-RVPU-0011-R3A-SM-2XCAE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06054 H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VJYA-0001-SM-3NMDJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.953738 BRD-K48950795_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null external segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.824874 GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.962431 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.56533 H3K36me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K93457574 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32614 Perturb_7751_KD_RPP20_SRP155278 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.39629 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06416 MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_16832_OE_Myc_SRP250081 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.3919 flurbiprofen-3095 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCDC117 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44521 TCF7L2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null prednisolone_homo sapiens_gpl570_gse32962 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53318 HIV_Infected-mDC_None_GSE42058 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.09198 hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056395 GSE203158_0_v_14_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRCA1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKN-3 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.01876 PECR Pathway Commons Protein-Protein Interactions 1.0 null GSE178255_5_v_0_tlr4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE165122_0_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null BRD-K59239976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15955 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TAF1_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SIU8-0426-SM-4BRUE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.852629 GATA1-22383799-G1ME-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BRD-K26187220 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.7125 Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00541 TCF7L2 ENCODE Transcription Factor Targets 1.0 null Perturb_7540_OE_EWSR1FLI1_SRP273158 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 biological_process GO Biological Process Annotations 2015 1.0 null BRD-K16485616_mocetinostat_MCF7_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_7361_KD_KDM5A_SRP325972 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 EPHB1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00487774 imatinib_homo sapiens_gpl96_gds3046 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SOX15 Pathway Commons Protein-Protein Interactions 1.0 null Nucleus ambiguus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18774 SP1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLTM Pathway Commons Protein-Protein Interactions 1.0 null BRD-K35960502_NICLOSAMIDE_WSUDLCL2_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MAP4K4 Pathway Commons Protein-Protein Interactions 1.0 null ZFX-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC3724940__F5 PFOCR Pathway Figure Associations 2023 1.0 null USF2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.951564 mitochondrial nucleoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.605284 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U8T8-0126-SM-3DB94 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02566 GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.1836 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2781-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BYSL Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_1203_KO_Sp2/Sp1_SRP302435 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 TAF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.41728 YD10B CCLE Cell Line Gene CNV Profiles -1.0 -1.3467 RPL26L1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X62O-0005-SM-46MV1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20295 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.63825 homo GeneRIF Biological Term Annotations 1.0 null BRD-K99545815_PF-562271_HEPG2_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K79me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXA2_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE239541_5_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SW 780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.916545 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TEAD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TE9 CCLE Cell Line Gene CNV Profiles -1.0 -1.84996 GTEX-TMZS-0008-SM-47JWM GTEx Tissue Sample Gene Expression Profiles 1.0 0.863335 Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Midbrain, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20097 BRD-K52560704_methylstat_PC3_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null RAD21_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null CTCF Pathway Commons Protein-Protein Interactions 1.0 null Perturb_14323_KD_PDK1_SRP234024 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GTEX-TMMY-1126-SM-4DXSX GTEx Tissue Sample Gene Expression Profiles 1.0 1.25837 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I6-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210655_3_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null CTCF_GM20000_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null uterine cervix TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.614571 isocarboxazid-7383 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null estradiol-6968 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MYCN_01_296 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.61632 BRD-K12460934 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09493 BRD-K79090631_CGP-60474_A549_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null CTCF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_18Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.89421 FAM98B Pathway Commons Protein-Protein Interactions 1.0 null CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIRT6 ENCODE Transcription Factor Targets 1.0 null POLR1C Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RWS6-0926-SM-47JXE GTEx Tissue Sample Gene Expression Profiles 1.0 1.13061 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0126 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null BRD-K92356505 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03953 15471956-Table2 GeneSigDB Published Gene Signatures 1.0 null H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-922 TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 PMC9810535-41590_2022_1370_MOESM3_ESM.xlsx-Table_S7-MECOM_up_genes_MECOM Rummagene Transcription Factor Associations 2026 1.0 null lung HPA Tissue Protein Expression Profiles -1.0 -0.840053 eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RNOR-0426-SM-2TF4U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3442 MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12900_KD_IRF3_SRP298451 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.6538 15(S)-15-methylprostaglandin E2-7526 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-S32W-1926-SM-4AD63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.43363 macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null POU2F1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01735 Hypertension CTD Gene-Disease Associations 1.0 1.06116 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPP38 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K54233340_Dorsomorphin dihydrochloride_HCT116_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-OXRN-0005-SM-2I5EU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17708 synapse SynGO Synaptic Gene Annotations 1.0 null RPS10 Pathway Commons Protein-Protein Interactions 1.0 null EPOR LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00516322 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null UTP14A Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.77953 TFPI Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Precommissural nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30503 HPSE Pathway Commons Protein-Protein Interactions 1.0 null IRF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-1626-SM-2HMKK GTEx Tissue Sample Gene Expression Profiles 1.0 0.880585 BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18481 Perturb_12958_KO_KDSR_SRP308393 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.19135 BRD-K23024526 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1586 UNC119 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K24125966 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.69095 GTPBP1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_11122_KD_Eif3m_SRP162708 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.19176 HC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K36me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K64665523 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28985 MYC-19030024-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BRD-U88459701_atorvastatin_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2076_OE_PUM1_SRP072710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.66136 PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_II-Unnamed_1_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.46856 GTEX-XBEC-1226-SM-4AT65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.50909 BRD-K76694128_DCC-2036_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K57282030_JW-7-24-1_MCF10A_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K44224150 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26974 POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.856694 MZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.922919 SF3B2 Pathway Commons Protein-Protein Interactions 1.0 null GSE112761,GSE112767_1_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null RFX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLE CCLE Cell Line Gene Expression Profiles 1.0 3.40058 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.865225 GTEX-RVPV-0011-R11A-SM-2TF6F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11381 Fallopian Tube GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.24212 GTEX-R45C-0008-SM-48FF2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13191 posteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04045 KLE CCLE Cell Line Gene CNV Profiles 1.0 2.79884 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRF1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EML4 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_1204_KO_Sp2/Sp1_SRP302435 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IH-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K15378071 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10967 BRD-K91923964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.18672 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CLTC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03898 substantia nigra, pars compacta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48685 BRD-K37721603 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41823 organelle lumen COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 BRD-K89376690 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45927 mitochondrial part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3451-01A-02R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K33510044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2026 Perturb_8937_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.39125 H3K9ac_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NEFM LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00523084 JHH-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.00512 Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.77487 CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2814 CCLE Cell Line Gene Expression Profiles 1.0 1.85713 SP1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null RPLP2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_1207_KO_Sp4/Sp1_SRP302435 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null Perturb_9960_KD_XPO5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.35721 TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST ENCODE Transcription Factor Targets 1.0 null H3K27ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K91596921 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47463 striatum_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06581 COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.61293 H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29211 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.196999 smoothmuscle_8a HPA Tissue Sample Gene Expression Profiles -1.0 -1.03786 H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null periventricular stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.31063 GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.905 CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7198_KD_ICE1_SRP164752 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 BRD-K43594798 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68447 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.850845 GTEX-XMK1-1726-SM-4B64Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.900474 BRD-K38494391 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.96737 CTCF_fibroblast of pedal digit skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null UQCRH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0537 MPHOSPH10 Pathway Commons Protein-Protein Interactions 1.0 null CSNK1G2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00418141 GATA1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6844_KD_FTX_SRP243253 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.43395 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.47209 myopathy, lactic acidosis, and sideroblastic anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.225 Alpers-Huttenlocher syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SSR4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50091 KYSE510_OESOPHAGUS CCLE Cell Line Proteomics 1.0 2.20571 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16678 epiandrosterone-3306 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ERN2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0046823 Heart - Atrial Appendage GTEx Tissue Gene Expression Profiles 2023 1.0 1.32838 BRD-K88378636_withaferin-a_SKBR3_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.02908 intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null EIF2AK2 Pathway Commons Protein-Protein Interactions 1.0 null USF2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6012-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -2.01717 PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Combined oxidative phosphorylation deficiency 12 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.576 ATXN2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00502165 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.65215 posterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89321 15988031-TableS5 GeneSigDB Published Gene Signatures 1.0 null PMC10641274-mmc2.xlsx-FOXK1_Untreated-SYMBOL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null ETS1-20019798-JURKAT-HUMAN ChEA Transcription Factor Targets 2022 1.0 null lateral group of nuclei, right, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06481 GSE160083,GSE160084_2_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K01774461 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53757 PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_2-ETS1-bound_promoters_ETS1 Rummagene Transcription Factor Associations 2026 1.0 null BACH2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0054614 BRD-K19220233_JNK-9L_HME1_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K79me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SMARCC1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A19500257_geldanamycin_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K67868012_PI-103_MCF7_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null G142 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43921 outer CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40159 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.28093 GSE112761,GSE112767_1_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36317 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43697 PMC12079334-ADVS-12-2501734-s002.pdf-192-ENSG00000197808_ZNF461 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K23543737 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5998 PMC6724602-mbc-30-1272-s007.xlsx-EGR1_Target_Genes-Gene_ID_s_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16882 Fatty Liver CTD Gene-Disease Associations 1.0 1.56141 DHX15 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KIR2DL1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00622005 ChIP_SOX2_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-RWSA-0008-SM-47JYX GTEx Tissue Sample Gene Expression Profiles 1.0 1.07213 GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1262 NCI-H1299 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.27349 CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1105 CCLE Cell Line Gene Expression Profiles -1.0 -1.63346 FOSL2_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.872828 GTEX-QEG4-1226-SM-2S1P6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.937508 Perturb_8435_KD_DDX39A_ERP124101 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.19225 BRD-K75618633 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01903 pralidoxime-3066 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CHD1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DIS3 Pathway Commons Protein-Protein Interactions 1.0 null CRX-20693478-RETINA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SRSF4 Pathway Commons Protein-Protein Interactions 1.0 null PKP3 Pathway Commons Protein-Protein Interactions 1.0 null CWF19L1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K07351191 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03995 HSDL2 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE120413,GSE120447_0_v_5_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MPHOSPH6 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00579714 COLO 849 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.905764 SYK_druginhibition_281_GSE43510 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.19757 DNAJB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03474 POLR3C Pathway Commons Protein-Protein Interactions 1.0 null CEBPD_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K38170103 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.11195 RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Embryo Loss CTD Gene-Disease Associations 1.0 1.04051 NFE2L2-20460467-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K36me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null peptide biosynthetic process GO Biological Process Annotations 2023 1.0 null TCF12_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_14632_KD_MSI2_SRP067129 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.38848 Leigh disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.473 Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Substantia nigra, reticular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00184 REST_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08689 PMC8101445-mbc-32-475-s003.xlsx-HEK_Tim22_KD-Gene_names_AR Rummagene Transcription Factor Associations 2026 1.0 null H2BK15ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE88819_5_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-WWYW-0426-SM-3NB31 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.986707 preweaning lethality, complete penetrance IMPC Knockout Mouse Phenotypes 1.0 null SF3B1 Pathway Commons Protein-Protein Interactions 1.0 null EXOSC4 Pathway Commons Protein-Protein Interactions 1.0 null optic fiber layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72232 BRD-K57080016_selumetinib_HT29_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null membrane-enclosed lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.548535 Lung squamous cell carcinoma_LUSC_TCGA-85-7696-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10121_KO_NGLY1_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.66803 MAFF ENCODE Transcription Factor Targets 1.0 null GTEX-NPJ7-0011-R11A-SM-2I3E8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07894 Retrosplenial area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07283 inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.981241 stratum pyramidale of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25894 CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K33869336 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67521 Perturb_3647_KO_KDM1A_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.6414 MSTO211H CCLE Cell Line Gene CNV Profiles -1.0 -1.74435 H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null skin GTEx Tissue Gene Expression Profiles 1.0 0.981214 REST_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K03837143 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43521 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13986 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062051 epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061489 POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K40175214_torin-1_MCF7_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SOX2 ChEA Transcription Factor Targets 1.0 null GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.971191 BRD-K60781525 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25167 SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVUS-0011-R9A-SM-3GIJA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09604 GTEX-P4QT-1626-SM-2S1NP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10598 BRD-K87947369_VX-680_HT29_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null RPL22 Pathway Commons Protein-Protein Interactions 1.0 null COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.87101 PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null NCI-H2369 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.43352 BRD-K15714771 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02367 RPS4X Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE157594_6_v_4_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null ACC3 BioGPS Cell Line Gene Expression Profiles -1.0 -1.16476 MRPS14 Pathway Commons Protein-Protein Interactions 1.0 null mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11288 Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P4HB Pathway Commons Protein-Protein Interactions 1.0 null Perturb_16_KO_Mga_SRP314000 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.26957 ChIP_YY1_21170310 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BRD-K79090631_CGP-60474_HCC515_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-QDVJ-0008-SM-48U2E GTEx Tissue Sample Gene Expression Profiles 1.0 1.81888 GATA1_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.38909 OAS1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00604653 RBBP6 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00907175 Ebolavirus(EBOV)_5day_PBMCs_17725815_GSE8317 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.464701 YY1 ENCODE Transcription Factor Targets 1.0 null CTCF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1_G1E-ER4_mm9_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPS11 Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X5-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null meteneprost-7557 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TAF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.849872 FOXP2 ENCODE Transcription Factor Targets 1.0 null hsa-miR-1972 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 TSSK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58552 FOXP1-21924763-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-V1D1-0003-SM-3NMDP GTEx Tissue Sample Gene Expression Profiles 1.0 0.857673 GTEX-TKQ2-0008-SM-4DM5L GTEx Tissue Sample Gene Expression Profiles 1.0 1.5309 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.995026 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.99092 lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.70116 TET1 ChEA Transcription Factor Targets 1.0 null GTEX-WH7G-2026-SM-3NMBL GTEx Tissue Sample Gene Expression Profiles 1.0 0.871616 GTEX-T5JC-0008-SM-4DM6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.99259 GSE206270_2_v_0_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null organelle outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.113404 ATP4A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00654427 IRF2 JASPAR Predicted Transcription Factor Targets 1.0 null RPS28 Pathway Commons Protein-Protein Interactions 1.0 null PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_Ensembl_that_KD_acts_upon_AR Rummagene Transcription Factor Associations 2026 1.0 null BRD-K50721666 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07216 GNPTAB LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00541042 anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09069 BRD-K90155857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.93162 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.896804 heart_5a HPA Tissue Sample Gene Expression Profiles 1.0 0.847062 RPL36 Pathway Commons Protein-Protein Interactions 1.0 null RPL27 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K26503698 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16606 H4K91ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CSDE1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K11474067 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.70936 H3K27ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RCC1 Pathway Commons Protein-Protein Interactions 1.0 null Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOLM16 CCLE Cell Line Gene Expression Profiles 1.0 1.7178 BRD-K72609226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05091 ribosomal GeneRIF Biological Term Annotations 1.0 null RPL17 Pathway Commons Protein-Protein Interactions 1.0 null SRSF9 Pathway Commons Protein-Protein Interactions 1.0 null TEAD4_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GPATCH4 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_16778_KO_Tbet_SRP120994 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.6078 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.922319 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21134 gabapentin-2731 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null blood vessel GTEx Tissue Gene Expression Profiles -1.0 -0.943979 GSE227634,GSE228381_0_v_7_arid1a_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K57080016_-666_SKM1_6.0_h_80.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K33016067 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03974 BRD-K19817946 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41501 H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K86448296 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43826 superficial stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11178 SPTBN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14437 BRD-K94411351 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.28979 GTEX-RVPV-0008-SM-47JYW GTEx Tissue Sample Gene Expression Profiles 1.0 1.09091 gramine-2143 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10830421-41589_2023_1452_MOESM5_ESM.xlsx-HEK293T_MAX-Tg_tissues-Unnamed_0_MAX Rummagene Transcription Factor Associations 2026 1.0 null duodenum HPA Tissue Gene Expression Profiles 1.0 1.1278 non-membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.66399 DDX18 Pathway Commons Protein-Protein Interactions 1.0 null RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13998 FBLN2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00518782 Perturb_2041_KO_Abro1_SRP275730 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.51802 CTCF_fibroblast of villous mesenchyme_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K13049116_BMS-754807_HT29_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null cellular process GO Biological Process Annotations 2015 1.0 null fulvestrant-6872 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K21125528 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07769 H3K79me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06225 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6342_KO_LONP1/ATF4_SRP353442 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.80974 GTEX-U3ZH-0008-SM-4DXT2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37564 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA2_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X638-0003-SM-47JZ1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85665 H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K32882942 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02403 STAT3-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_1138_KO_Ahr_ERP113014 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.78681 BRD-K73528610 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.44577 E2F6_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bj HPA Cell Line Gene Expression Profiles -1.0 -0.949494 BRD-K15940471 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15008 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SRSF7 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K48549243 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07227 BRD-K01077691 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2734 BRD-K90485414 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61417 PBX3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null decreased cardiac muscle contractility MGI Mouse Phenotype Associations 2023 1.0 null lack GeneRIF Biological Term Annotations 1.0 null PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1 Rummagene Transcription Factor Associations 2026 1.0 null C14orf166 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14601_KO_ASAP2_SRP258574 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 brain GTEx Tissue Gene Expression Profiles -1.0 -1.01965 intermediate stratum of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72604 MRM1 Pathway Commons Protein-Protein Interactions 1.0 null SNRPC Pathway Commons Protein-Protein Interactions 1.0 null cinoxacin-2722 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-A07407288 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68884 mantle zone of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32907 primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.35375 HNMT LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00634133 GTEX-U4B1-0326-SM-3DB8K GTEx Tissue Sample Gene Expression Profiles 1.0 0.980481 NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16555 PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K50424430 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08974 BRD-A06929388_-666_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ATF1 ENCODE Transcription Factor Targets 1.0 null GTEX-RU72-0011-R9A-SM-2TF67 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62215 GABPA_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A19500257_geldanamycin_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1304 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.35029 HMGB1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K68608492 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18762 PC-14 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.76491 superficial stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56027 KOPN-8 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.48721 BRD-K49345010 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1295 ASH2L-23239880-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE66724_DE-Genes_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05092 H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H4K5ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PNO1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11075 GTEX-OHPL-0006-SM-3MJHB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1967 FAM207A Pathway Commons Protein-Protein Interactions 1.0 null H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null chlorpromazine-1055 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null simvastatin-3002 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE210655_3_v_4_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null lateral group of nuclei, left, ventral division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17253 PLK1 Pathway Commons Protein-Protein Interactions 1.0 null H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EIF3F Pathway Commons Protein-Protein Interactions 1.0 null GSE214442_0_v_1_pak4_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1068_OE_PHF19_SRP188592 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.03659 superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14755 r7 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07072 ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.28608 CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null NOM1 Pathway Commons Protein-Protein Interactions 1.0 null decreased exploration in new environment MGI Mouse Phenotype Associations 2023 1.0 null BRD-K62888534 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.75466 H3K79me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.839179 KSR1_knockout_126_GSE28228 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.85947 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.827386 H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PLOD1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XUZC-1726-SM-4BRWS GTEx Tissue Sample Gene Expression Profiles 1.0 0.831754 DDX42 Pathway Commons Protein-Protein Interactions 1.0 null U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.16195 must GeneRIF Biological Term Annotations 1.0 null GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17298 translational termination GO Biological Process Annotations 2015 1.0 null H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PML ENCODE Transcription Factor Targets 1.0 null KHDRBS1 Pathway Commons Protein-Protein Interactions 1.0 null SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21525 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null FGFBP1 Pathway Commons Protein-Protein Interactions 1.0 null HNRNPA1 Pathway Commons Protein-Protein Interactions 1.0 null YY1_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13501_KD_WDR5_SRP261594 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.3267 adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.429547 ABCF1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POP1 Pathway Commons Protein-Protein Interactions 1.0 null TRMT112 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K74138110 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50888 ZNF474 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15085 TRMT61A Pathway Commons Protein-Protein Interactions 1.0 null MAX Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_344_OE|KD_SMAD1|GDF6_SRP076553 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 RNF138 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21591 LYL1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null RBM39 Pathway Commons Protein-Protein Interactions 1.0 null H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-A19500257_geldanamycin_MCF7_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K07350528 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07905 BRD-K30258816 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.81559 FOXM1 ENCODE Transcription Factor Targets 1.0 null CD8B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00539012 BRD-K85546819 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21754 intermediate stratum of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2672 BRD-K34028745 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75825 BRD-U70626184_BI-2536_PC3_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null mitochondrial matrix GO Cellular Component Annotations 2023 1.0 null PPP3CB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08701 posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.937103 RPL32 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_GM12872_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null EWSR1 Pathway Commons Protein-Protein Interactions 1.0 null CPEB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2787 AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null BRD-K35442564 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1666 CEBPB ENCODE Transcription Factor Targets 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.09933 posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10448 BRD-K35942122 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10174 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RPL18 Pathway Commons Protein-Protein Interactions 1.0 null NCIH660 CCLE Cell Line Gene Expression Profiles -1.0 -3.24923 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.903575 KP-1N COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.056 SP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAV1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00602561 CTCF_SK-N-SH_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null sox4_16636670_acc3_lof_human_gpl96_gds2193 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.440662 CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPZ ENCODE Transcription Factor Targets 1.0 null UTP3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-UPJH-0926-SM-4IHKA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.901592 BRD-K19220233_JNK-9L_A549_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null LOUCY GDSC Cell Line Gene Expression Profiles -1.0 -1.87226 GTEX-SUCS-0326-SM-32PLL GTEx Tissue Sample Gene Expression Profiles 1.0 0.931799 Perturb_16469_KD_BAZ1B_ERP118000 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.9882 KLF4 ChEA Transcription Factor Targets 1.0 null MEI1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00597321 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TG-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null YY1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null presynaptic ribosome SynGO Synaptic Gene Annotations 1.0 null DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.62254 BRD-K33775409 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16962 TUBA1C Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67006 TRIM25 Pathway Commons Protein-Protein Interactions 1.0 null estradiol_homo sapiens_gpl570_gse11352 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33214 POLR2A_K562_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4XY-0006-SM-46MV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2884 azathioprine-5627 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 CTCF_MCF-7_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null benzydamine-1552 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-68-A59I-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CKAP4 Pathway Commons Protein-Protein Interactions 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null Perturb_9194_KD_DDX3X_SRP299259 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AK5ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7399_KD_AFF2_SRP009568 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.95251 IARS Pathway Commons Protein-Protein Interactions 1.0 null 11-deoxy-16,16-dimethylprostaglandin E2-7519 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K07303502_Arachidonyl trifluoro-methyl ketone_VCAP_6.0_h_80.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.880628 GTEX-TMMY-0626-SM-33HBD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1385 Perturb_7400_KD_AFF3_SRP009568 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.10255 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.891207 RBM42 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NFIC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K08406395 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34857 IGSF8 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00579384 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Inflammation CTD Gene-Disease Associations 1.0 1.19966 BCL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07502 GTEX-XPT6-0001-SM-4B64G GTEx Tissue Sample Gene Expression Profiles 1.0 0.936213 tiaprofenic acid-2492 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46748 superficial stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81495 POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC-20876797-MEDULLOBLASTOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SMARCB1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00447894 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.33179 NRF1 JASPAR Predicted Transcription Factor Targets 1.0 null NR3C1_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Ribosomal protein S12/S23 InterPro Predicted Protein Domain Annotations 1.0 null Perturb_12182_KD_PALB2_SRP015361 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.46028 Nemaline Myopathy_Gastrocnemius Muscle_GSE3384 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.79952 PIP4K2A Pathway Commons Protein-Protein Interactions 1.0 null DEL CCLE Cell Line Gene Expression Profiles -1.0 -1.63217 KDM1A ENCODE Transcription Factor Targets 1.0 null TEAD4_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K03624299 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.00647 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14615 E2F1-26619117-HEPATOCYTES-MOUSE-LIVER ChEA Transcription Factor Targets 2022 1.0 null IRF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GB1_CENTRAL_NERVOUS_SYSTEM CCLE Cell Line Proteomics 1.0 2.30677 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16555 BRD-K69718434 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30574 RAD21_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02909 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.6492 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Granulomatous Disease, Chronic_Blood neutrophil_GSE935 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.97546 POLR2A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNRPE Pathway Commons Protein-Protein Interactions 1.0 null CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.966603 GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.945465 NSUN2 Pathway Commons Protein-Protein Interactions 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.860041 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_1606_KO_Tnfaip3_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.48225 Lactic acidosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.134 BRD-K83090041 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06365 hippocampus (hippocampal formation)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.880702 type GeneRIF Biological Term Annotations 1.0 null COX4I1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02929 ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25257 BRD-K92433833 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.06427 Perturb_11568_OE_SIX4_SRP166969 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.97823 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5886-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.00383 pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14828 Nrf-1 MotifMap Predicted Transcription Factor Targets 1.0 null endometrium_8b HPA Tissue Sample Gene Expression Profiles -1.0 -2.12846 CTCF_GM12865_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 20174566-TableS1 GeneSigDB Published Gene Signatures 1.0 null BRD-K44432556_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE148692,GSE148695_5_v_6_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K42486632 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2954 Perturb_14186_KD_GFI1_SRP289469 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.52656 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K42008693 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15281 BRD-K28339544 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16972 CLPB Pathway Commons Protein-Protein Interactions 1.0 null lateral superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31654 GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.958565 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.123 GTEX-QEG4-0008-SM-48TYZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.83604 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.34026 pyramidal layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.879345 PCBP2 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K98301999 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14313 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32516 GSE174586_0_v_1_slc4a11_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE178560_0_v_1_irf7_mouse RummaGEO Gene Perturbation Signatures 1.0 null MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.88717 mantle zone of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03424 periventricular part of StrSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32949 Brain Lower Grade Glioma_LGG_TCGA-FG-6692-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8828_KD_DDX60L_SRP313537 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59021 Perturb_7898_KD_NCL_SRP337780 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.62332 CTCF_GM12864_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11732233-mmc1.pdf-52-MYT1L_MYT1L Rummagene Transcription Factor Associations 2026 1.0 null RAD21_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6488577-41598_2019_43010_MOESM2_ESM.xlsx-Proteingroups_MBD3_pos-Gene_names_MBD3 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Uterus GTEx Tissue Gene Expression Profiles 2023 1.0 0.42011 GR MotifMap Predicted Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.177851 Perturb_7003_KO_Acadl/Acadvl_SRP323582 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.36638 RPS15 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10641274-mmc2.xlsx-FOXK1_Untreated-ENSEMBL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null MET_knockout_257_GSE25583 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 0.805148 ETS1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K08174111 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23334 cellular biosynthetic process GO Biological Process Annotations 2015 1.0 null NELFA-20434984-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null caudal interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06977 REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null III, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04328 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35604 proglumide-2363 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K67090983_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75782 phenelzine-2357 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F4_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11750912-12032_2025_2606_MOESM1_ESM.xlsx-AR_vs_AC-Name_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE195513_0_v_3_cpeb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.53846 central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3267 Bladder GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.35391 CTCF_GM12867_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K73681382 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26512 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A560-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23374 cytoplasmic chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.60444 posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.973819 CIRBP Pathway Commons Protein-Protein Interactions 1.0 null POLR2AphosphoS5_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K68916730 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09078 BRD-K33783177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.07123 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.987103 H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SN8G-0008-SM-4DM4X GTEx Tissue Sample Gene Expression Profiles 1.0 1.8412 aminoglycoside-induced deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.19 GTEX-UPIC-1126-SM-4IHLO GTEx Tissue Sample Gene Expression Profiles 1.0 1.02657 ZBTB16 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0069102 BRD-A77907596 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01048 PABPC1 Pathway Commons Protein-Protein Interactions 1.0 null RPS4Y1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-N7MS-0008-SM-4E3JI GTEx Tissue Sample Gene Expression Profiles 1.0 0.878874 BRD-K38519440 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04174 Infertility, Female CTD Gene-Disease Associations 1.0 1.34372 ERBB2_knockdown_236_GSE8373 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.08797 IRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K36074653 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27551 protein complex disassembly GO Biological Process Annotations 2015 1.0 null CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SERPINC1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00428538 TSR1 Pathway Commons Protein-Protein Interactions 1.0 null RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWN1-0008-SM-48TEA GTEx Tissue Sample Gene Expression Profiles 1.0 1.53645 Perturb_12965_KD_YTHDC1_SRP325534 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.6322 H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TRIM28_knockout_301_GSE32224 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.4431 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16062 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16678 GTEX-WHWD-0426-SM-3LK83 GTEx Tissue Sample Gene Expression Profiles 1.0 0.860468 membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052699 BRD-K47849061 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.48005 Perturb_1205_KO_Sp2/Sp3_SRP302435 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 SKN-3 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 MRPL18 Pathway Commons Protein-Protein Interactions 1.0 null YY1_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT1-20625510-HELA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-QV31-0008-SM-447AT GTEx Tissue Sample Gene Expression Profiles 1.0 2.13513 BRD-K36063519 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14838 CUX1 ENCODE Transcription Factor Targets 1.0 null MICU2 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFIC ENCODE Transcription Factor Targets 1.0 null MTA3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00887 PEG10 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-A75409952_wortmannin_HT29_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null organellar ribosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 ILF3 Pathway Commons Protein-Protein Interactions 1.0 null PMC2820592-NIHMS144142-supplement-8.xls-LMS_SAM_3-GENES_HIGHLY_EXPRESSED_IN_GROUP_III_LMS_TP63 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -2.18734 MRPS27 Pathway Commons Protein-Protein Interactions 1.0 null COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22232 GTEX-WFG8-1626-SM-4LVMB GTEx Tissue Sample Gene Expression Profiles 1.0 0.988994 NPRL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01874 LOXIMVI Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.84443 GSE62292,GSE62295_2_v_0_col4a3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_8443_KD_TOP2A_ERP124101 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.32961 DDRGK1 Pathway Commons Protein-Protein Interactions 1.0 null dorsal preisthmic part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3061 Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLIRP Pathway Commons Protein-Protein Interactions 1.0 null BRD-K62072978 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10968 MZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01236 BRD-K79148949 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34742 CREB1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DDX6 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K70379342 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.89734 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.948638 BRD-K19009595 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3321 BRD-K87904882_chelerythrine chloride_HEPG2_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null zidovudine-5333 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-POMQ-0008-SM-48TE7 GTEx Tissue Sample Gene Expression Profiles 1.0 2.46183 LB647-SCLC Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.18862 Combined oxidative phosphorylation deficiency 7 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.6 BRD-K08307026_-666_SKB_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K28071390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.85582 BRD-K19752998 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12549 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null API5 Pathway Commons Protein-Protein Interactions 1.0 null H3K36me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SAMD3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00496801 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.135 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NME2 Pathway Commons Protein-Protein Interactions 1.0 null CEBPD-21427703-3T3-L1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37847 BRD-K29415052_NVP-BGT226_PC3_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE149880_2_v_1_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null RAD21_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null poly(a) rna binding GO Molecular Function Annotations 2015 1.0 null NOC2L Pathway Commons Protein-Protein Interactions 1.0 null Perturb_194_KD_Slpi_SRP056340 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.92303 8-MG-BA GDSC Cell Line Gene Expression Profiles 1.0 1.66395 BRD-K69491845 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51398 A-CA-04-2009(H1N1)_0Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.58551 GTEX-XPVG-0726-SM-4B658 GTEx Tissue Sample Gene Expression Profiles 1.0 0.843909 MAGT1 Pathway Commons Protein-Protein Interactions 1.0 null SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.900783 HCFC1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GPR143 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00471919 KYSE70_OESOPHAGUS CCLE Cell Line Proteomics 1.0 2.02702 H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE133213_9_v_15_znrf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K84450674_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DAZAP1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Perturb_16857_OE_Sp1_SRP077934 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 ST13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28966 Perturb_14501_KO_Tgfb3_SRP020224 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.85201 BRD-K46155894 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09693 cerebellar cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.31165 H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Anterior cingulate area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05268 cellular component organization GO Biological Process Annotations 2015 1.0 null GTEX-T5JW-1126-SM-4DM5V GTEx Tissue Sample Gene Expression Profiles 1.0 1.30298 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOGS Pathway Commons Protein-Protein Interactions 1.0 null SNRPD3 Pathway Commons Protein-Protein Interactions 1.0 null MYBBP1A Pathway Commons Protein-Protein Interactions 1.0 null BRD-K84310612 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07515 GTEX-XQ8I-0126-SM-4BOPL GTEx Tissue Sample Gene Expression Profiles 1.0 0.921737 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-K54507743 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23317 BRD-K76176797 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38707 naloxone-4645 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.87565 superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15116 esophageal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.410535 PGD Pathway Commons Protein-Protein Interactions 1.0 null PMC2724271__F4 PFOCR Pathway Figure Associations 2023 1.0 null GTEX-Q2AI-0008-SM-48U2H GTEx Tissue Sample Gene Expression Profiles 1.0 2.40604 BRD-K49755501 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05095 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46748 DNAJC13 Pathway Commons Protein-Protein Interactions 1.0 null CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.47063 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null COLO680N CCLE Cell Line Gene CNV Profiles 1.0 1.6562 TBP_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRMT6 Pathway Commons Protein-Protein Interactions 1.0 null mitochondrial translation GO Biological Process Annotations 2015 1.0 null GSE228413_0_v_3_mavs_mouse RummaGEO Gene Perturbation Signatures -1.0 null Liver GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.08091 H4K91ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K43389698_BMS-387032_HME1_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K81592842 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25092 GTEX-XOT4-1426-SM-4B65T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03502 TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null lateral part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36355 NR2E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55743 GTEX-NPJ8-0011-R8a-SM-2HMLG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.859612 BRD-K44760023 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.7344 indoprofen-3007 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.86635 USF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7SF-0426-SM-3K2B7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00327 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NOP56 Pathway Commons Protein-Protein Interactions 1.0 null H4 CCLE Cell Line Gene CNV Profiles 1.0 1.52862 CHRND LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00616114 GTEX-OOBJ-1526-SM-3NB1Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.872204 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 NR3C1 ENCODE Transcription Factor Targets 1.0 null bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.175895 TAF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K04010869_PROSTAGLANDIN A1_CL34_6.0_h_1.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.877026 disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039385 CTCF_GM10248_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UBAP2L Pathway Commons Protein-Protein Interactions 1.0 null CTCF_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null digestive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 BRD-K32370845 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1448 BRD-K30257736 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26016 GSE136233,GSE136234_0_v_1_zpbp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CREB1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U412-0008-SM-4DXTE GTEx Tissue Sample Gene Expression Profiles 1.0 1.21215 lateral part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61529 NFIC JASPAR Predicted Transcription Factor Targets 1.0 null RL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 2.72717 BRD-A79768653_sirolimus_WSUDLCL2_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K44236678 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.97211 GTEX-XLM4-0004-SM-4AT5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.31182 PMC11750912-12032_2025_2606_MOESM1_ESM.xlsx-AA_vs_AC-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null TBC1D14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26782 MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null receptorassociated GeneRIF Biological Term Annotations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03118 POLR2AphosphoS5_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.09888 GSE62843,GSE64371_2_v_3_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-R55E-1326-SM-48FCR GTEx Tissue Sample Gene Expression Profiles 1.0 0.992742 GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40307 ribavirin_homo sapiens_gpl570_gds4391 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K11700411 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03459 Lung squamous cell carcinoma_LUSC_TCGA-34-5241-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K92291448 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84447 PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-GeneID_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.98607 H3K27ac_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null sin3a_22783022_mcf7_lof_human_gpl570_gds4388 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.132495 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.69077 dorsal part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30715 EIF3D Pathway Commons Protein-Protein Interactions 1.0 null GABPA_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PP-0008-SM-48TDV GTEx Tissue Sample Gene Expression Profiles 1.0 0.9214 Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K13038935 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16885 19965622-TableS1a GeneSigDB Published Gene Signatures 1.0 null hsa-miR-135a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03875 EIF3L Pathway Commons Protein-Protein Interactions 1.0 null DDX39B Pathway Commons Protein-Protein Interactions 1.0 null GUK1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00812984 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null olivary pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82437 KP-N-YN GDSC Cell Line Gene Expression Profiles -1.0 -1.6151 ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K20288742 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51742 estradiol_homo sapiens_gpl570_gse5102 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K51556300_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_8438_KD_KPNA2_ERP124101 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.99529 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29903 CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CMTM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08539 CTCF_fibroblast of gingiva_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A95239561 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4052 BRD-K94037108 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41362 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14735_KD_ADAR1_SRP250165 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.76626 RAD51AP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2375 SARS-CoV MA15_Day4-C57BL-6_None_GSE40824 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.63404 SF3B3 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K95537020 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.64336 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14696 BRD-K30379413 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.79786 H3K36me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2752_KD_ADAM12_SRP077683 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 PMC4335056-pone.0116726.s005.xlsx-X-ChIP_NOT_TX100_QE-GENE_Official_symbol_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null POLR3D Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11985509-41467_2025_58704_MOESM7_ESM.xlsx-ZNF385A_vs_WT-Unnamed_1_ZNF385A Rummagene Transcription Factor Associations 2026 1.0 null BRD-K69932463_AZD8055_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE183271_2_v_3_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.84581 Edema CTD Gene-Disease Associations 1.0 1.38974 palmatine-2138 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TE5 CCLE Cell Line Gene Expression Profiles -1.0 -1.68624 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC3724940__F5 PFOCR Pathway Figure Associations 2024 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null t30-blood-rna_male_8w MoTrPAC Rat Endurance Exercise Training 1.0 5.33963 TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NKM-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.6837 H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K76353834 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54951 BRD-K30895360 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0959 H3K4me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null imatinib_homo sapiens_gpl96_gds3049 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HADHB Pathway Commons Protein-Protein Interactions 1.0 null Retrosplenial area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2035 Perturb_16792_KD_SPIB_SRP124308 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.84544 GSE139427_2_v_1_ibrutinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.974963 striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.964353 H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_7310_KO_TP53_SRP350326 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.75907 BRD-K52321331_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null POLR2AphosphoS5_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRPS7 Pathway Commons Protein-Protein Interactions 1.0 null HNRNPA0 Pathway Commons Protein-Protein Interactions 1.0 null 12917485-Table6 GeneSigDB Published Gene Signatures 1.0 null GTEX-Q2AH-1826-SM-2S1Q2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03359 BRD-A79768653_sirolimus_SW620_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.837215 BRD-K71303366_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.69251 GTEX-QV31-0126-SM-447BP GTEx Tissue Sample Gene Expression Profiles 1.0 0.878821 deferasirox_homo sapiens_gpl570_gds3558 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K56411643_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null LUC7L3 Pathway Commons Protein-Protein Interactions 1.0 null SB-202190-6887 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K41859756_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null hsa-miR-615-3p MiRTarBase microRNA Targets 1.0 null CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K12184916_NVP-BEZ235_MCF10A_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.31082 FOXJ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08866 Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16678 organelle LOCATE Predicted Protein Localization Annotations 1.0 null r5 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28216 primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.98786 GTEX-W5X1-0001-SM-3P61V GTEx Tissue Sample Gene Expression Profiles 1.0 1.24404 H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SIU8-0008-SM-4BRUC GTEx Tissue Sample Gene Expression Profiles 1.0 1.4919 GTEX-QMRM-1226-SM-447C6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08767 HOXB4-20404135-EML-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P44H-0006-SM-2XCFB GTEx Tissue Sample Gene Expression Profiles -1.0 -2.42598 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18033 BRD-K95196255_-666_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null LDB1-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCIH661_LUNG CCLE Cell Line Proteomics 1.0 2.6213 GTEX-OOBJ-0008-SM-3NB26 GTEx Tissue Sample Gene Expression Profiles 1.0 2.70815 HSPA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32633 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS2ST1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XUJ4-2026-SM-4BOOW GTEx Tissue Sample Gene Expression Profiles 1.0 1.22896 PLAGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42827 POU2F2 ENCODE Transcription Factor Targets 1.0 null DHX16 Pathway Commons Protein-Protein Interactions 1.0 null PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null rostromedial tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05185 TYW5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43916 HDQP1_BREAST CCLE Cell Line Proteomics 1.0 2.52398 AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.58706 ETS1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-499-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 BRD-K05804044_AZ-628_HT29_24_h_0.04_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_16513_KD_C11orf53_SRP343255 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.0415 BRD-A47829399_artesunate_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-TKQ1-0003-SM-3NMAE GTEx Tissue Sample Gene Expression Profiles 1.0 1.1662 GTEX-XUJ4-1226-SM-4BOPD GTEx Tissue Sample Gene Expression Profiles 1.0 0.987032 GTEX-QEG5-0926-SM-2TC64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45476 mantle zone of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72677 GTEX-T6MN-0002-SM-3NMAH GTEx Tissue Sample Gene Expression Profiles 1.0 0.934948 MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50156 PARN Pathway Commons Protein-Protein Interactions 1.0 null BRD-K35171408 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11778 dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.457 RAD21_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12867_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H4K20me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.36748 BRD-K41875112 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25307 BRD-K44576681 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22449 SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SIX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K38403252 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.51661 RAD21_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GPKOW Pathway Commons Protein-Protein Interactions 1.0 null Perturb_15272_KD_Tardbp_SRP254218 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.60324 YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Farage Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.28518 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.89412 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.833617 E2F6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE112763,GSE112767_0_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K35587518 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15352 PGR-26153859-MCF-7-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null GTEX-SNOS-1226-SM-4DM5H GTEx Tissue Sample Gene Expression Profiles 1.0 0.892449 PMC8384902-mmc5.xlsx-H2107_PROX1_ChIP-Symbol_PROX1 Rummagene Transcription Factor Associations 2026 1.0 null skin_5f HPA Tissue Sample Gene Expression Profiles -1.0 -1.58485 17683608-TableS2 GeneSigDB Published Gene Signatures 1.0 null FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K01667746 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19514 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SU8686 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 H3K4me1_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K27305650_LY-294002_A375_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null intermediate stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90867 GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.870965 BRD-K74329400 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4503 LNZ308 CCLE Cell Line Gene Expression Profiles 1.0 1.82361 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K48777375 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52053 H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.829461 Perturb_16779_KO_Tbet_SRP120994 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.6242 H3K36me3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HARS Pathway Commons Protein-Protein Interactions 1.0 null Lung BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.04364 mantle zone of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28216 BRD-K81473043_-666_MCF7_24.0_h_0.35_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null structural molecule activity GO Molecular Function Annotations 2015 1.0 null H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3730_KO_Atf7ip_SRP327190 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.41208 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.86141 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.050401 GTEX-SNOS-0008-SM-4DM6I GTEx Tissue Sample Gene Expression Profiles 1.0 2.50062 skin_6a HPA Tissue Sample Gene Expression Profiles 1.0 0.984731 Perturb_13444_KD_Taf4_SRP119047 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.42544 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63708 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A44990218 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29708 H3K9me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NR2F2 ENCODE Transcription Factor Targets 1.0 null MV-4-11 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.50985 TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12878 Perturb_7402_KD_HNRNPA1_SRP010280 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.81676 BRD-K17570530 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18364 H3K36me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null SR 27897 DeepCoverMOA Drug Mechanisms of Action 1.0 0.26 BRD-K00423214 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52728 cellular component disassembly GO Biological Process Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-LA-A446-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE203158_12_v_15_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null H2BK120ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_13273_KO_Spen_SRP198728 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.73607 CCDC124 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K46149271 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1593 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.40376 ACOT9 Pathway Commons Protein-Protein Interactions 1.0 null POLR2AphosphoS5_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CMK CCLE Cell Line Gene Expression Profiles 1.0 1.44312 CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCT4-21477851-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HMGB3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XYKS-0002-SM-4BRWN GTEx Tissue Sample Gene Expression Profiles 1.0 1.4654 CTCF_GM12865_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K73579545 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32501 GTEX-VUSG-0003-SM-3NMDK GTEx Tissue Sample Gene Expression Profiles 1.0 1.23508 PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null cytoplasmic part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EP300_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28459 GTEX-WFJO-0008-SM-4LVN7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.82578 H3K27ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mitochondrion LOCATE Curated Protein Localization Annotations 1.0 null estradiol_homo sapiens_gpl571_gds4052 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RPL5 Pathway Commons Protein-Protein Interactions 1.0 null transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01436 MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.44496 HNRNPF Pathway Commons Protein-Protein Interactions 1.0 null estradiol_homo sapiens_gpl96_gds2324 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_epithelial cell of esophagus_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A11702965_230752_PHH_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_A549_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null principal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05149 SNU1076 CCLE Cell Line Gene CNV Profiles -1.0 -2.25607 SBC-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.97379 GSE178255_3_v_7_tlr4_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.49995 SP1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UJHI-1126-SM-4IHLN GTEx Tissue Sample Gene Expression Profiles 1.0 0.871101 H4K20me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CREB1-23762244-HIPPOCAMPUS-RAT ChEA Transcription Factor Targets 2022 1.0 null ribonucleoprotein GeneRIF Biological Term Annotations 1.0 null GTEX-UPK5-0008-SM-4IHJD GTEx Tissue Sample Gene Expression Profiles 1.0 1.10647 NIPSNAP1 Pathway Commons Protein-Protein Interactions 1.0 null 18535662-TableS2b GeneSigDB Published Gene Signatures 1.0 null H3ac_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_1065_Mut_Esr1_SRP087718 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.25576 mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null Acquired Immunodeficiency Syndrome HuGE Navigator Gene-Phenotype Associations 1.0 null MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1395 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.779997 ZC3HAV1 Pathway Commons Protein-Protein Interactions 1.0 null GSE252857_2_v_3_prednisone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WFJO-0002-SM-3P61X GTEx Tissue Sample Gene Expression Profiles 1.0 1.17138 PRPF8 Pathway Commons Protein-Protein Interactions 1.0 null POU2F2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null USP7 Pathway Commons Protein-Protein Interactions 1.0 null Pain CTD Gene-Disease Associations 1.0 1.03864 Breast - Mammary Tissue GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.744565 BRD-K46269666 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75156 NCI-H1666 GDSC Cell Line Gene Expression Profiles 1.0 1.75249 RPL23 Pathway Commons Protein-Protein Interactions 1.0 null DPY30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23996 FASTKD2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00487949 GSE172295_3_v_2_sh3gl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null mitochondrial GeneRIF Biological Term Annotations 1.0 null SNU-C2B GDSC Cell Line Gene Expression Profiles 1.0 1.46282 BRD-A11154023 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22088 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K15019832 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22315 propofol-3048 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Neurotoxicity Syndromes CTD Gene-Disease Associations 1.0 1.06008 GABPA_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.974092 ribonucleoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.485289 RAD21_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Colorectaladenocarcinoma BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.02177 Perturb_15347_KD_SMARCD1_SRP269169 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.76017 TNFRSF13B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0051677 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ATG16L1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00595424 TAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50581 BRD-A19500257_geldanamycin_MCF7_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null GSE166536_1_v_2_docetaxel_mouse RummaGEO Drug Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TOX4 Pathway Commons Protein-Protein Interactions 1.0 null EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PBX3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE185944_0_v_3_pth1r_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XGQ4-1526-SM-4AT6H GTEx Tissue Sample Gene Expression Profiles 1.0 1.039 Guanfacine DeepCoverMOA Drug Mechanisms of Action -1.0 -0.69 abnormal hepatocyte morphology MGI Mouse Phenotype Associations 2023 1.0 null BRD-K57293986 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28266 Perturb_8371_KO_Myc/Mlxipl_SRP148418 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -14.9037 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-N7MT-0011-R4a-SM-2I3G9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00402 MYBL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null p2 portion of the substantia nigra pars reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14006 H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL8 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K24792153 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.7705 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1_G1E-ER4_mm9_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVJO-0008-SM-447AU GTEx Tissue Sample Gene Expression Profiles 1.0 2.64537 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null succinylsulfathiazole-2821 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NCI-H250 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 mitochondrial matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.819911 CKAP5 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_WI38_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF384_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZR75_1 BioGPS Cell Line Gene Expression Profiles -1.0 -1.24542 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_5659_KO_SA2_SRP201842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.92799 H2AFZ ENCODE Transcription Factor Targets 1.0 null p1 part of the substantia nigra reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22872 SUB1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PWOO-1326-SM-48TCJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.0837 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2191 PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null ACTR10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44063 mitochondrial outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.158882 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16142 amygdaloid complex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.62676 PARP1 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82B-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4507-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K57678861_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ChIP_NR0B1_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BRD-K39681206 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12337 Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SSBP1 Pathway Commons Protein-Protein Interactions 1.0 null HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null small ribosomal subunit GO Cellular Component Annotations 2023 1.0 null PMC4494960-oncotarget-06-12587-s002.xlsx-LNCaP_MYC_Microarray-Table_S1_MYC Rummagene Transcription Factor Associations 2026 1.0 null organelle part GO Cellular Component Annotations 2015 1.0 null galantamine-2131 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-RN64-1226-SM-2TC6E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29497 DRAXIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36827 MYC_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30332 RPS8 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K63970901 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43313 primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.27047 LY-294002-6935 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null C19orf44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07023 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26935 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K17514980 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50036 POLR2AphosphoS2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PTCD3 Pathway Commons Protein-Protein Interactions 1.0 null NFATC1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUJ4-0004-SM-4BOQE GTEx Tissue Sample Gene Expression Profiles 1.0 1.27741 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.978763 MEWO_SKIN CCLE Cell Line Proteomics 1.0 5.70811 macromolecule biosynthetic process GO Biological Process Annotations 2023 1.0 null SNB75 BioGPS Cell Line Gene Expression Profiles -1.0 -0.901014 Perturb_9662_OE_ATF4_SRP259940 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 EIF3C Pathway Commons Protein-Protein Interactions 1.0 null Perturb_3030_KO_Acta2_SRP353808 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 19.699 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.128 Pleural Effusion CTD Gene-Disease Associations 1.0 1.08091 ribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.609509 TAF1_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASF1A Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9052_KD_CACTIN_SRP075920 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.9318 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.40905 GABPA_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GAS2L3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00642104 GTEX-QEL4-0926-SM-3GAD1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18027 GSE152055_2_v_3_mpc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.58332 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32099 Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spinal nucleus of the trigeminal, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11469 ATP5C1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2751_KD_ADAM12_SRP077683 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE137177_1_v_0_folic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null intermediate stratum of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45532 C8G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15337 ATAD3A Pathway Commons Protein-Protein Interactions 1.0 null GTEX-W5WG-0008-SM-4KL25 GTEx Tissue Sample Gene Expression Profiles 1.0 1.354 SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1428 CCLE Cell Line Gene CNV Profiles -1.0 -1.612 GTEX-P44H-0011-R4A-SM-2XCEW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.992484 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K26335565 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.60953 SYK_knockdown_191_GSE54065 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.81514 A204 BioGPS Cell Line Gene Expression Profiles -1.0 -2.016 PMC2999557-pone.0015082.s016.xls-target_genes-top10_H3K9me3_SETDB1_overlap_SETDB1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K47108422 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32115 USF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.962313 H2BC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34344 valproic acid-458 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K04454173 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.80898 SSB Pathway Commons Protein-Protein Interactions 1.0 null BRD-K98249237 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0751 BMP5 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00712804 OAW28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.12191 BRD-K50841342_PAC 1_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ribosome biogenesis GO Biological Process Annotations 2023 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ICAM2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00452636 triflupromazine-7466 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null r9 part of the basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43697 Perturb_17557_KO_STING1_SRP358852 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.92622 BRD-K37558338 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36375 hyoscyamine-1424 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Micronuclei, Chromosome-Defective CTD Gene-Disease Associations 1.0 1.07447 GTEX-NL4W-0008-SM-4E3I2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.898202 RAD21_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE203158_0_v_13_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K16190564 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3039 MCM5 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.96346 BRD-K83012560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.52092 CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCPAP GDSC Cell Line Gene Expression Profiles -1.0 -1.47841 GTEX-T5JW-0926-SM-4DM5K GTEx Tissue Sample Gene Expression Profiles 1.0 0.880985 Perturb_10039_KD_UBE2L3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.08185 POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-U61997977_WZ-4-145_HME1_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE240027,GSE240030_5_v_2_atrx_mouse RummaGEO Gene Perturbation Signatures 1.0 null NFYB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HA-E2F1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.10774 Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K98695520 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83389 MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA ChEA Transcription Factor Targets 2022 1.0 null small-subunit processome GO Cellular Component Annotations 2023 1.0 null EW8 CCLE Cell Line Gene CNV Profiles 1.0 1.72473 GTEX-P78B-0008-SM-48TE1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.80795 abnormal translation MGI Mouse Phenotype Associations 2023 1.0 null CFAP46 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0071494 anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.935919 BRD-K88996418 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4783 Chronic progressive external ophthalmoplegia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.43 BRD-K34489843 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29014 Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K23628938 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06757 Perturb_8733_KD_KIF20A_SRP229081 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GSE122067_3_v_1_mtch2_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K46298074 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.56547 PRPF4 Pathway Commons Protein-Protein Interactions 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null GTEX-WZTO-1126-SM-3NM93 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824117 H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null vitamin c_homo sapiens_gpl6884_gse16590 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-U3ZN-0002-SM-3NMDF GTEx Tissue Sample Gene Expression Profiles 1.0 0.955605 intracellular organelle GO Cellular Component Annotations 2015 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null TEAD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K78902613 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40145 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF Rummagene Transcription Factor Associations 2026 1.0 null PTRH1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00482654 trifluoperazine-5442 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null dorsal terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7168 Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GABP-19822575-HEPG2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCAPH LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00535196 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.931404 CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mitochondrial translational termination GO Biological Process Annotations 2015 1.0 null BRD-K73025859 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60491 POLR2A_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR0B1-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null ventrolateral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02799 BRD-K67898193 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01442 GSE112763,GSE112767_0_v_1_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K74860368 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02065 BRD-K38630090 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.11049 PSPC1 Pathway Commons Protein-Protein Interactions 1.0 null lymphnode_5b HPA Tissue Sample Gene Expression Profiles 1.0 0.956763 ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MCTP2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00489763 BRD-K14359942 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29102 BRD-K09635314_-666_HT115_6.0_h_80.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CCNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7535 Neurobehavioral Manifestations CTD Gene-Disease Associations 1.0 1.05864 DPY19L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05556 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FIP1L1 Pathway Commons Protein-Protein Interactions 1.0 null Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03 Perturb_6300_KD_CGA_SRP355115 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 YY1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K53561341_HY-70061_HT29_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Combined oxidative phosphorylation deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.141 mitochondrial translation GO Biological Process Annotations 2023 1.0 null Perturb_3372_KO_Cblb_SRP347245 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.93381 CCT2 Pathway Commons Protein-Protein Interactions 1.0 null EP300_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K25907192 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.63877 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18595 SLC27A2 Pathway Commons Protein-Protein Interactions 1.0 null MAPK14_knockdown_101_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.76484 BRD-A34492468 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29507 POLR2A_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null 8305C_THYROID CCLE Cell Line Proteomics 1.0 2.64403 pancreas HPA Tissue Gene Expression Profiles -1.0 -0.932768 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TSE9-0011-R9A-SM-3DB7Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36535 BRD-K34703146 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32618 CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsp70 GeneRIF Biological Term Annotations 1.0 null 18497862-TableS2 GeneSigDB Published Gene Signatures 1.0 null HNRNPU Pathway Commons Protein-Protein Interactions 1.0 null GSE127790_11_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null TTF2-22483619-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K28467941 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00079 RPSA Pathway Commons Protein-Protein Interactions 1.0 null SPTLC3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.006421 19843711-TableS2 GeneSigDB Published Gene Signatures 1.0 null H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CUX1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K25149224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01587 GTEX-O5YU-0008-SM-4E3I7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.972498 BRD-K36740062_HY-70044_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null seneciphylline-2140 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF-33576154-HUMAN-LIVER-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null BRD-K54837058 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.82155 epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.336704 Perturb_6777_KD_BRD4_ERP024018 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.5685 CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ1-0006-SM-33HBI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.929616 BRD-A35495382 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12316 BRD-K32282076 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27585 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.871209 cefalexin-5250 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null doxorubicin_homo sapiens_gpl10558_gse42531 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NR2F2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX2-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_4570_KD_Hnrnpf/Hnrnph1_SRP186998 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.56492 SP2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K67408816 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32254 organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null BCLAF1 ENCODE Transcription Factor Targets 1.0 null H3K4me1_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.936279 INCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22278 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.881486 OSRC2_KIDNEY CCLE Cell Line Proteomics 1.0 2.49206 GSE198165,GSE198166_9_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null ACLY Pathway Commons Protein-Protein Interactions 1.0 null BRD-K54362440 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2264 buspirone-1282 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTF2B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DDAH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.388 nucleus of Darkschewitsch, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.879459 baclofen-2036 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SIN3A_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Schwalie et al.Nature.G4_Adipose tissue_Mouse CellMarker Gene-Cell Type Associations 1.0 null NPY2R LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0050319 Perturb_4583_KO_Socs3_SRP074146 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.42213 GATA1_G1E-ER4_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-1226-SM-4AT5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.930859 binding GO Molecular Function Annotations 2015 1.0 null GTEX-OHPN-0011-R2A-SM-2I5FB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55059 CREB1-23762244-HIPPOCAMPUS-RAT ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09018 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP3-21729870-TREG-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CDX2-21402776-INTESTINAL-VILLUS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PATL1 Pathway Commons Protein-Protein Interactions 1.0 null diethylstilbestrol_rattus norvegicus_gpl1355_brown norway_gds2913 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null neostigmine bromide-2432 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU869 CCLE Cell Line Gene Expression Profiles -1.0 -2.05909 TROVE2 Hub Proteins Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07452 BRD-K60429174 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59628 Perturb_10771_KO_Jnk2_SRP038635 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.90049 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29219 AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null BRD-A19500257_geldanamycin_HEPG2_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-REY6-1226-SM-48FDR GTEx Tissue Sample Gene Expression Profiles 1.0 1.28559 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25789 E2F1 JASPAR Predicted Transcription Factor Targets 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057874 GTEX-S7SE-0008-SM-33HB1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35067 RNA binding GO Molecular Function Annotations 2023 1.0 null ribonucleoprotein complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01673 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19537 CTCF_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4631_KO_Ddx1_SRP348296 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.76582 Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7PM-0008-SM-3NM9Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.23161 GFAP Pathway Commons Protein-Protein Interactions 1.0 null PMC11385366-Table2.xlsx-DBP-Overlapped_Gene_DBP Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UTHO-0011-R3A-SM-3GIK8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.880222 DDX46 Pathway Commons Protein-Protein Interactions 1.0 null HNRNPK Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null DDOST Pathway Commons Protein-Protein Interactions 1.0 null H3K56ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ergocalciferol-3304 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_9714_KO_miR34a_SRP058984 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.32832 Spinal nucleus of the trigeminal, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49188 GTEX-RU72-1226-SM-2TF6N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873157 G141 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36198 GTEX-XOT4-1126-SM-4B66E GTEx Tissue Sample Gene Expression Profiles 1.0 0.885714 CPSF1 Pathway Commons Protein-Protein Interactions 1.0 null SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Peripheral motor neuropathy_Sciatic Nerve_GSE1947 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.34958 primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.2855 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S3XE-0008-SM-3NM8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.20637 GSE186620_0_v_1_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ChIP_CTCF_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.963121 MARVELD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39784 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null MYC_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K44139682 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15997 carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.389666 Perturb_213_OE_Mettl7a1_SRP357594 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.80087 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.848055 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAP3K13 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00626824 H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null KY821 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 3.48466 CTCF_MEL cell line_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ8-0011-R1a-SM-33HCB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.90739 Breast Neoplasms CTD Gene-Disease Associations 1.0 1.23042 GTEX-V955-0004-SM-3NMDH GTEx Tissue Sample Gene Expression Profiles 1.0 0.848119 mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null 18757322-TableS1 GeneSigDB Published Gene Signatures 1.0 null BRD-K22485581 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.47701 CTCF_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UGGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63259 BRD-A62025033_temsirolimus [CI779]_A673_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Headache CTD Gene-Disease Associations 1.0 1.03939 endometrium HPA Tissue Gene Expression Profiles -1.0 -0.937421 RPL4 Pathway Commons Protein-Protein Interactions 1.0 null POLR2AphosphoS5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LRRC47 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OIZI-0526-SM-2XCEG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.963579 GSE250534_0_v_3_cabergoline_mouse RummaGEO Drug Perturbation Signatures 1.0 null posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.984906 Perturb_9519_KO_Dync2h1_SRP131479 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.2635 BRD-K83972459_JWE-035_MCF7_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A39996500_radicicol_MCF7_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null organelle membrane GO Cellular Component Annotations 2015 1.0 null BRD-K12347309 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.93086 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.97467 dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.64014 RPL35 Pathway Commons Protein-Protein Interactions 1.0 null TMEM175 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00656311 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63756 Cardiovascular Diseases CTD Gene-Disease Associations 1.0 1.0241 Behr syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178 GTEX-UTHO-0011-R4A-SM-3GIJP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42387 BRD-K49865102_PD-0325901_HT29_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05737 BRD-K91511557 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60317 Perturb_14278_KO_Clec4e_SRP262935 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.432 BRD-K30594227 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.86646 USF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K14970242 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67052 dentate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10312 RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle organization GO Biological Process Annotations 2015 1.0 null GSE252857_2_v_3_klf15_mouse RummaGEO Gene Perturbation Signatures -1.0 null Infertility, Male CTD Gene-Disease Associations 1.0 1.02262 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.170114 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cuneate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09727 CSNK2B Pathway Commons Protein-Protein Interactions 1.0 null EIF5B Pathway Commons Protein-Protein Interactions 1.0 null Perturb_13251_KO_Dux_SRP098643 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.45409 ATP5A1 Pathway Commons Protein-Protein Interactions 1.0 null RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A75409952_wortmannin_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K65529782 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.89283 POP5 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K33939287 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53559 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RPL19 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K89402302 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17074 CPSF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21627 KPNYN CCLE Cell Line Gene Expression Profiles -1.0 -1.5916 TAF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.50744 Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A27080191 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24527 H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KCNN3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00751387 TEAD4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HSC4 CCLE Cell Line Gene Expression Profiles -1.0 -1.89276 H1FX Pathway Commons Protein-Protein Interactions 1.0 null GSE240027,GSE240030_1_v_0_atrx_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-U29336476_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.15475 BRD-K60662039 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84228 PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PVOW-0008-SM-48TE8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.86562 KHSRP Pathway Commons Protein-Protein Interactions 1.0 null BRD-K30201819 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09072 BRD-A79768653_sirolimus_HME1_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K23192422_L-6307_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Hemorrhage CTD Gene-Disease Associations 1.0 1.34897 YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Early enterocyte precursor cell_Intestinal crypt_Mouse CellMarker Gene-Cell Type Associations 1.0 null BRD-K77908580_S1053_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -3.55911 Adrenocortical carcinoma_ACC_TCGA-OR-A5J7-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nucleus ambiguus, dorsal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36948 GSE166317_3_v_0_j147_mouse RummaGEO Drug Perturbation Signatures -1.0 null r6 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25468 lateral spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2962 NFYA_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Early myoclonic encephalopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.24 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5881-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsomedial preoptic area, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11178 H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2759-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null L3MBTL3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.005741 BRD-K04363234 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.213 Perturb_6428_KD_ADAR1_SRP009659 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Nausea CTD Gene-Disease Associations 1.0 1.13862 Perturb_3946_KD_PRDX2_SRP075061 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 15489886-TableS1a GeneSigDB Published Gene Signatures 1.0 null LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.867499 POLR2AphosphoS5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8913_KO_KDM1A_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.3729 Perturb_12199_KD_XPC_SRP310546 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null organellar ribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.22153 ATF2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE215351,GSE215794_4_v_3_kdm8_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCIH2452 CCLE Cell Line Gene CNV Profiles -1.0 -1.83663 rolipram-6730 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null mitochondrial translational elongation GO Biological Process Annotations 2015 1.0 null KIAA0020 Pathway Commons Protein-Protein Interactions 1.0 null MRPL41 Pathway Commons Protein-Protein Interactions 1.0 null GSE232836_2_v_6_morphine_mouse RummaGEO Drug Perturbation Signatures -1.0 null NOC3L Pathway Commons Protein-Protein Interactions 1.0 null such GeneRIF Biological Term Annotations 1.0 null putamen, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.850559 H1F0 Pathway Commons Protein-Protein Interactions 1.0 null membrane-enclosed lumen COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 ventrolateral prefrontal cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.853254 BRD-K20722478 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13221 BRD-K76937233 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50141 BRD-K03351377 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.64853 fluphenazine-494 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null XRN2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23126 BRD-A01759464 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13865 CTCF_GM12864_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K97445906 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03346 SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.16191 BRD-K80462316 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68629 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.986008 acetazolamide-1850 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_6048_KD_PIAS2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 ncoa_22072566_ly2_lof_human_gpl570_gds4095 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.359872 BRD-U64521890_XMD16-144_SKBR3_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11296 GSE151494_1_v_9_nrp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K44328896 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26334 SRSF1 Pathway Commons Protein-Protein Interactions 1.0 null TMEM52B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00605657 Perturb_94_KD_B4GALNT1_SRP127547 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.58523 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null AP2A1 Pathway Commons Protein-Protein Interactions 1.0 null Skin - Not Sun Exposed (Suprapubic) GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.16594 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TAF15 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K02159791 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49597 BRD-K50140257 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05001 Perturb_2010_KO_Pgrn_SRP371355 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 19.1549 metabolic process GO Biological Process Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-01A-12R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 15474998-tableS1c GeneSigDB Published Gene Signatures 1.0 null GRB7 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K56801250 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10409 Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K90863245 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43078 shell part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00455 BRD-K13257316 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6245 pioglitazone-7528 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SLC1A3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -3.91573 SCC25_UPPER_AERODIGESTIVE_TRACT CCLE Cell Line Proteomics 1.0 3.06291 BRD-K07557785 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16034 CCT6A Pathway Commons Protein-Protein Interactions 1.0 null mediodorsal nucleus of thalamus_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.66118 CEBPB_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DHX9 Pathway Commons Protein-Protein Interactions 1.0 null PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null H2BK20ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K92462786 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10613 Perturb_1157_KO_Myc_SRP150708 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 ATF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AURKA_knockdown_89_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.95399 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT5A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TJP2 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K74211805 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62047 lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -0.840053 H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null EIF2S1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RM2N-1826-SM-2TF5B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40465 SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.982597 Perturb_11579_KO_QPC_SRP166848 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.66957 BRD-K13390322_AT-7519_HT29_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K43966357 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81194 GATA1_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07015 BRD-K91796483 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77355 AIMP1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K98522669 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62513 Perturb_18498_KO_KIF3B_SRP359974 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.77409 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null colliculus superior Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2962 BRD-K33573676 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1128 BRD-K38046923 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2213 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYOG ENCODE Transcription Factor Targets 1.0 null rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.29655 deferoxamine_homo sapiens_gpl91_gse1056 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null DKMG CCLE Cell Line Gene Expression Profiles -1.0 -1.94691 PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.96674 GSE185944_2_v_1_pth1r_mouse RummaGEO Gene Perturbation Signatures -1.0 null ATF3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mammillary part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33247 GTEX-S341-0008-SM-4AD6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.51608 GTEX-TML8-0001-SM-3NMAF GTEx Tissue Sample Gene Expression Profiles 1.0 1.36496 MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SJXC-0426-SM-2XCFH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.96069 MRPL15 Pathway Commons Protein-Protein Interactions 1.0 null ATP5D Pathway Commons Protein-Protein Interactions 1.0 null CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.883471 PAX5_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null cisapride-3305 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.71313 BRD-K78762661 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1426 MAP4 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K71737889 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05688 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null tamoxifen_homo sapiens_gpl3921_gse33366 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.951804 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.26628 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SHP-77 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.56285 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cellular protein complex disassembly GO Biological Process Annotations 2015 1.0 null GTEX-XPT6-2226-SM-4B66R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.831785 18757322-TableS2 GeneSigDB Published Gene Signatures 1.0 null H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K62102480 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31712 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22771 Cloacal exstrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.148 P30-OHK COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27ac_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 RAN MSigDB Cancer Gene Co-expression Modules 1.0 null central nucleus of the inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10714 GTEX-R55E-0011-R11A-SM-2TC6I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.894785 DBR1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K87947369_VX-680_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K63068307_HY-50847_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K77625799_vandetanib_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K58288048_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.16641 OVCAR4 BioGPS Cell Line Gene Expression Profiles 1.0 1.29446 Perturb_17054_KO_Ccna2_ERP105671 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.67041 Perturb_3279_KD_RORC_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 A549 CCLE Cell Line Gene Expression Profiles 1.0 1.70988 RSL1D1 Pathway Commons Protein-Protein Interactions 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.4394 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01626 H3K27ac_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.03564 heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K24978625 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08293 CTH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08875 GTEX-RUSQ-0826-SM-47JWW GTEx Tissue Sample Gene Expression Profiles 1.0 1.20019 GABPA_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DLG1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00369952 protein metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K61717269_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_10223_KD_FOXC1_SRP068208 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.5487 Perturb_14214_KO_App_SRP254653 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.06093 RUVBL1 Pathway Commons Protein-Protein Interactions 1.0 null BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_3277_KD_RORA_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 embryoday7.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.25964 BRD-K56309946 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39621 H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RBM14 Pathway Commons Protein-Protein Interactions 1.0 null mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01207 RBM26 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XPVG-0526-SM-4B65N GTEx Tissue Sample Gene Expression Profiles 1.0 1.02901 Esophagus - Muscularis GTEx Tissue Gene Expression Profiles 2023 1.0 2.85697 POLR3A Pathway Commons Protein-Protein Interactions 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.61913 EWS502 CCLE Cell Line Gene CNV Profiles -1.0 -1.40453 SETDB1 ENCODE Transcription Factor Targets 1.0 null BRD-K32131036 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15499 H3K27ac_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-OOBK-0008-SM-3NB27 GTEx Tissue Sample Gene Expression Profiles 1.0 2.00706 BRD-K07762528 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07902 GTEX-PX3G-0008-SM-48U2L GTEx Tissue Sample Gene Expression Profiles 1.0 1.51903 GTEX-T5JW-1326-SM-4DM5G GTEx Tissue Sample Gene Expression Profiles 1.0 0.891488 PMC10746608-427_2023_709_MOESM5_ESM.xlsx-SOX2_partners-SOX2_known_protein_partners_according_to_BioGrid_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null pituitary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.36609 SMURF2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-N7MT-0126-SM-2D7VT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835003 Perturb_2526_KD_ZRANB2_SRP185438 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.90069 lateral part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4545 MZ in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.957836 BRD-K77108738 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47578 MRPL11 Pathway Commons Protein-Protein Interactions 1.0 null Heart Defects, Congenital CTD Gene-Disease Associations 1.0 1.06625 TAF7 ENCODE Transcription Factor Targets 1.0 null ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.681074 BRD-K30269093 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.86936 blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05733 GSE157594_6_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null Perturb_16444_KO_Kdm5b_SRP291684 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.49257 TAF1_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K79090631_CGP-60474_HEPG2_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K51967704_S1175_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.91599 GTEX-U3ZN-0008-SM-4DXTL GTEx Tissue Sample Gene Expression Profiles 1.0 1.40412 layer 2 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29477 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.02903 H3K4me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RAD21_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34009 SRPR Pathway Commons Protein-Protein Interactions 1.0 null cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.64672 DHX38 Pathway Commons Protein-Protein Interactions 1.0 null LYST LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00757847 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Sarcoma_SARC_TCGA-QC-A6FX-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPN-0011-R4A-SM-2I5FD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40759 MAX ENCODE Transcription Factor Targets 1.0 null intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null RIF1 Pathway Commons Protein-Protein Interactions 1.0 null RNF2-27304074-CHIP-SEQ-NSC-MOUSE ChEA Transcription Factor Targets 2022 1.0 null increased hepatocyte proliferation MGI Mouse Phenotype Associations 2023 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XK95-0008-SM-4AT5G GTEx Tissue Sample Gene Expression Profiles 1.0 1.44894 mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.7407 RELA_GM15510_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFYA_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55D-1126-SM-48FEB GTEx Tissue Sample Gene Expression Profiles 1.0 0.97685 RPL31 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null specifically GeneRIF Biological Term Annotations 1.0 null BRD-K81660107 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10343 TAF7_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LN229_CENTRAL_NERVOUS_SYSTEM CCLE Cell Line Proteomics 1.0 2.85636 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.02042 YY1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.279659 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 3.15479 Perturb_13968_KD_Ago2_ERP133202 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.62325 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K86966177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05197 DUSP6 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00750022 ZNF384 ENCODE Transcription Factor Targets 1.0 null BRD-K00744507 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.33697 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.913891 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.824259 TAF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-U07805514_saracatinib_A549_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CDC42 Pathway Commons Protein-Protein Interactions 1.0 null NANOG-18692474-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Transit amplifying (TA) cell_Intestinal crypt_Mouse CellMarker Gene-Cell Type Associations 1.0 null JHH-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.09714 GTEX-RWS6-2326-SM-2XCB4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55961 BRD-K69337311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10568 H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HUPT3 CCLE Cell Line Gene CNV Profiles -1.0 -2.02293 RPL38 Pathway Commons Protein-Protein Interactions 1.0 null DoTc2-4510 GDSC Cell Line Gene Expression Profiles -1.0 -1.62538 CELSR2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00617961 Perturb_1118_KD_SENP6_SRP328207 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.49526 BRD-K40816903 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16729 H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SP1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.966977 POLR2A_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TSPAN7 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0066639 H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CAPRIN1 Pathway Commons Protein-Protein Interactions 1.0 null POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ECGI10 CCLE Cell Line Gene CNV Profiles -1.0 -1.83371 KCNA1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00780984 BRD-K19220233_JNK-9L_HEPG2_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K93459372 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.04601 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.854414 BRD-K91564773 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19454 SNU1105_CENTRAL_NERVOUS_SYSTEM CCLE Cell Line Proteomics 1.0 2.44148 NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05813 PNPLA6 Pathway Commons Protein-Protein Interactions 1.0 null TAL1 ENCODE Transcription Factor Targets 1.0 null CTCF_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K65503129_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K90284572 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11183 GTEX-S341-0626-SM-4AD5T GTEx Tissue Sample Gene Expression Profiles 1.0 0.947371 HSF1_01_178 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59325 membrane GO Cellular Component Annotations 2015 1.0 null 19218430-TableS3 GeneSigDB Published Gene Signatures 1.0 null BRD-K23673040_(Naphthalen-1-ylamino)-acetic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide_A375_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_765_KD_ZFR_SRP107875 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.7248 duodenum_4b HPA Tissue Sample Gene Expression Profiles 1.0 1.3744 MRPS28 Pathway Commons Protein-Protein Interactions 1.0 null trovafloxacin_homo sapiens_gpl96_gse9166 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null YBX3 Pathway Commons Protein-Protein Interactions 1.0 null Nucleic acid-binding, OB-fold InterPro Predicted Protein Domain Annotations 1.0 null BRD-K16891407 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.427 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SF3A3 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_3278_KD_RORC_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PARK7_KD_GDS3750_2_human_SH-SY5Y GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K13566078_HY-10518_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-WFON-0001-SM-3P61W GTEx Tissue Sample Gene Expression Profiles 1.0 1.30172 JUND_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K38258132 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38338 GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07063 H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF3 ENCODE Transcription Factor Targets 1.0 null RAD21_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE167218_1_v_0_hoxd12_mouse RummaGEO Gene Perturbation Signatures -1.0 null orbital frontal cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.47096 Prestwick-692-2165 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null POLR2A_GM19193_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nfy GeneRIF Biological Term Annotations 1.0 null ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.69453 wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.302074 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.989382 GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35819 BRD-A45498368_WYE-125132_MCF7_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MATR3 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K68174511_torin-2_MCF10A_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r6 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2023 AGO1_02_162 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.62698 Perturb_2737_KD_NIK_SRP332892 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.866 translational initiation GO Biological Process Annotations 2015 1.0 null ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW403_LARGE_INTESTINE CCLE Cell Line Proteomics 1.0 2.84986 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RPL3 Pathway Commons Protein-Protein Interactions 1.0 null TADA2B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00517732 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65157 Infantile hypertrophic cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 GTEX-PWCY-0008-SM-48TE9 GTEx Tissue Sample Gene Expression Profiles 1.0 2.2405 HDAC6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null way GeneRIF Biological Term Annotations 1.0 null BRD-K86027709_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K27ac_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null suramin sodium-7529 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53746 BRD-K15607890 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54098 H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060818 CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13692_KD_NSD2_SRP064418 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.7149 GSE129858,GSE129859_1_v_3_robo1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K29460044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18777 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27843 BRD-K79090631_CGP-60474_HME1_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE80446_2_v_1_anakinra_mouse RummaGEO Drug Perturbation Signatures 1.0 null mantle zone of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30539 ELK1 ChEA Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29C-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3022 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K89524688 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01773 H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PTBP3 Pathway Commons Protein-Protein Interactions 1.0 null H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ8-0426-SM-2HMK6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.33177 GTEX-TKQ2-0826-SM-33HB6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19593 Brain glioblastoma multiforme DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.381 GTEX-TSE9-1226-SM-4DXTM GTEx Tissue Sample Gene Expression Profiles 1.0 0.827838 NR0B1 ChEA Transcription Factor Targets 1.0 null CHEK1_knockdown_95_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.8633 THRAP3 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_GM18951_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K88494268 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04674 BRD-K44432556_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32874 H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K06876397 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42967 Perturb_5658_KO_SA2_SRP201842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.27087 Perturb_16458_KO_CHUK_SRP229998 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_hic_ZBTB12 Rummagene Transcription Factor Associations 2026 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K75845970 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.79955 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH6_LIVER CCLE Cell Line Proteomics 1.0 3.3614 FUOV1 CCLE Cell Line Gene Expression Profiles 1.0 1.73582 BRD-K37398853 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10975 Perturb_7619_OE_OspC1_SRP368098 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.55548 H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CDKN2AIP Pathway Commons Protein-Protein Interactions 1.0 null GSE112765,GSE112767_1_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XGQ4-0004-SM-4AT5S GTEx Tissue Sample Gene Expression Profiles 1.0 1.22957 HKDC1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K42757676 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16376 MCF7 BioGPS Cell Line Gene Expression Profiles 1.0 0.991483 GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39115 PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-0926-SM-2HMIZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16712 metrifonate-5989 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-A19633847_PERHEXILINE MALEATE_THP1_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null lateral group of nuclei, right, ventral division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2271 PRPF6 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PSDG-0526-SM-2S1OH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15937 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.86901 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K24502602 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59682 PMC3226433-1756-8935-4-20-S1.XLS-Table_S5_Miz-1_KD_gene_exp_chan-Genes_up-regulated_in_Miz-1_KD_hESC_AR Rummagene Transcription Factor Associations 2026 1.0 null CTCF_GM12868_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P44H-0008-SM-48TDW GTEx Tissue Sample Gene Expression Profiles 1.0 2.31856 CREB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4763_KO_DLG2_SRP315088 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 BRD-K16798053_ST4029573_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Anterior cingulate area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28443 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039531 BCAS2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_10075_KD_AQR_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.2944 EIF4B Pathway Commons Protein-Protein Interactions 1.0 null GNL2 Pathway Commons Protein-Protein Interactions 1.0 null TRIP13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60481 mediodorsal nucleus of thalamus_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.48935 RAD21 ENCODE Transcription Factor Targets 1.0 null BRD-K76938712_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ZCCHC3 Pathway Commons Protein-Protein Interactions 1.0 null Inferior colliculus, central nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46582 valproic acid-1647 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39961 Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K06666320_-666_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PLAUR LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00457638 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RPL36A Pathway Commons Protein-Protein Interactions 1.0 null CTCF_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SSA3-0326-SM-32QPS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19011 GTEX-U3ZN-2526-SM-3DB7V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829141 BRD-K38571893 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46218 organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039606 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05988 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01735 Perturb_10909_KD_Eif3m_SRP157047 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.19176 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EO-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07016 LUC7L2 Pathway Commons Protein-Protein Interactions 1.0 null MARK2 Pathway Commons Protein-Protein Interactions 1.0 null rbm15_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.051155 PPP1R10 Pathway Commons Protein-Protein Interactions 1.0 null HNRNPM Pathway Commons Protein-Protein Interactions 1.0 null EP300_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K36883526 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.53589 BRD-K26282994 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.51161 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.17372 SOX6-21985497-MYOTUBES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_15436_KD_NUSAP1_SRP074246 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.1877 GTEX-U8XE-0826-SM-4E3J1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.834544 H3K79me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LRRC59 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K18984088 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0952 Optic nerve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.166 CTCF_GM12865_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K88038091 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.7713 RPS23 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PW2O-0226-SM-48TC7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.973353 H3K36me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ELK1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null valproic acid_homo sapiens_gpl96_gds1050 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MICU1 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRPRB Pathway Commons Protein-Protein Interactions 1.0 null KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16555 GCAT LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00508589 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.31783 BRD-K14788918_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null nucleic acid binding GO Molecular Function Annotations 2015 1.0 null PUS7 Pathway Commons Protein-Protein Interactions 1.0 null STAT5A ENCODE Transcription Factor Targets 1.0 null mitochondrion COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 RAD21_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS 852.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.19287 cerebellar cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19155 HS 675.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.36837 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EXOSC6 Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.964353 17638893-SuppTable7 GeneSigDB Published Gene Signatures 1.0 null BRD-A71001587 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14768 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K07496812 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43307 GSE116354,GSE117379_2_v_4_cox2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ARID3A ENCODE Transcription Factor Targets 1.0 null RPN1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE144796_3_v_0_linagliptin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.24668 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056165 BRD-K99545815_PF-562271_A549_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.912105 H3K79me1_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 16280042-GeneList GeneSigDB Published Gene Signatures 1.0 null Perturb_8945_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.8139 pregnenolone-2497 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K01754882 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.95622 CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE223540_2_v_3_anxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25018 CTCF ChEA Transcription Factor Targets 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.920803 cellular_component GO Cellular Component Annotations 2015 1.0 null SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69127 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055572 NANOG-16518401-CHIP-PET-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CAL-62 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.85554 BRD-K28598371 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.90334 HEXIM2 Pathway Commons Protein-Protein Interactions 1.0 null pc3 HPA Cell Line Gene Expression Profiles 1.0 1.05351 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.902831 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04342 GATA1_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RARS Pathway Commons Protein-Protein Interactions 1.0 null layer 4 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00926 GTEX-QVUS-0008-SM-447AY GTEx Tissue Sample Gene Expression Profiles 1.0 2.2273 GTEX-QCQG-1626-SM-48U26 GTEx Tissue Sample Gene Expression Profiles 1.0 0.902333 GSE178255_1_v_0_tlr4_mouse RummaGEO Gene Perturbation Signatures -1.0 null IL17RB LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00508476 GTEX-X585-0002-SM-46MVA GTEx Tissue Sample Gene Expression Profiles 1.0 1.30279 GTF3C1 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bacterial Infection_Peripheral blood mononuclear cell_GSE3026 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -3.33596 PBX3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.58361 GTEX-N7MS-0626-SM-2YUN7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.65879 CEBPB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CSTF3 Pathway Commons Protein-Protein Interactions 1.0 null PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null MYC-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K43495666 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.92267 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11725_KO_Ikka_SRP229998 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 BRD-K79937734 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48038 medial mammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45532 Intracranial Hypertension CTD Gene-Disease Associations 1.0 1.01512 CCT3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PWO3-0011-R1A-SM-2I5EW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17296 Perturb_10861_KO_Med23_SRP027536 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.78012 BRD-K18724229_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K72060858 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6411 GTEX-PWO3-0011-R5A-SM-2I5EZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844236 CHD2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24273 NANOG-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mitochondrial chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.605284 CNBP Pathway Commons Protein-Protein Interactions 1.0 null DYNLT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00179 H4K5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WFG7-0008-SM-4LMKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.42444 Perturb_7710_KO_VTRNA1_SRP252980 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.48973 propoxycaine-7155 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RBM15 Pathway Commons Protein-Protein Interactions 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-K87909389_alvocidib_A549_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null superficial stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.24392 CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX2-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-XV7Q-0226-SM-4BRVL GTEx Tissue Sample Gene Expression Profiles 1.0 1.04621 MS-1 GDSC Cell Line Gene Expression Profiles -1.0 -1.80409 GSE216538_5_v_6_mrs2_mouse RummaGEO Gene Perturbation Signatures -1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045386 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16555 OVCAR-3 GDSC Cell Line Gene Expression Profiles 1.0 2.93977 FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null THAP11-20581084-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null rh30 HPA Cell Line Gene Expression Profiles -1.0 -0.898898 YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS675T CCLE Cell Line Gene Expression Profiles -1.0 -1.45199 POLR2A_GM12891_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XYKS-0008-SM-4BRW6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14094 ISG20L2 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_WERI-Rb-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.1747 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RWS6-0001-SM-3NMAL GTEx Tissue Sample Gene Expression Profiles 1.0 0.840951 H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null translation at presynapse SynGO Synaptic Gene Annotations 1.0 null GTEX-SSA3-0008-SM-47JWJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.6438 GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.88431 KASUMI-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.79054 BRD-K38380337 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.73675 KDM1A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cetuximab_homo sapiens_gpl570_gse21483 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null UBLC1_URINARY_TRACT CCLE Cell Line Proteomics 1.0 4.19724 BRD-K20853228 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40381 RPS3A Pathway Commons Protein-Protein Interactions 1.0 null regulation of canonical Wnt signaling pathway GO Biological Process Annotations 2023 1.0 null SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.52036 embryonic lethality prior to organogenesis IMPC Knockout Mouse Phenotypes 1.0 null internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29362 TCF12_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null Inner ear disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.496 GTEX-RM2N-1626-SM-2TF5N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.826487 BRD-K39179354 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30759 FUS Pathway Commons Protein-Protein Interactions 1.0 null Interstitial cell_Fetal kidney_Human CellMarker Gene-Cell Type Associations 1.0 null BRD-K27597444 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.00816 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null XRCC5 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6707_KD_ELOA_SRP314942 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.38571 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRDM14 ChEA Transcription Factor Targets 1.0 null PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_8_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null BRD-K55116708_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HIST1H1D Pathway Commons Protein-Protein Interactions 1.0 null mantle zone of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29477 periventricular stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00131 GTEX-QMR6-0011-R1A-SM-32PKW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.930208 Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.091 JSC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.2274 GTEX-OOBJ-1026-SM-3NB2L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19893 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10155 USF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null layer 1 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3302 Salivarygland BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.39407 intracellular non-membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PU.1-20513432-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7246_KO_MBD1/MBD2/MBD4/MECP2_SRP337936 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.60535 ventral paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1414 BRD-K58242935 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19295 GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09972 CTCF_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WEY5-2126-SM-3GILK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04507 GTEX-P4QS-1126-SM-3NMD5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.938352 POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT5A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5550_KO_FBXO11_SRP149805 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.91353 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052699 NCI-H2009 COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 POLR2A_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRDM14-21183938-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null heat GeneRIF Biological Term Annotations 1.0 null BRD-K21826560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31545 bounding membrane of organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.046593 r10 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61666 MYLK3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00573362 GTEX-X4XY-1626-SM-46MVN GTEx Tissue Sample Gene Expression Profiles 1.0 0.977464 17638893-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.09048 HSPB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07905 GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67789 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K20755323_-666_PC3_24.0_h_40.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null LARP1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K55459289 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.70185 GATA1_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SUPV3L1 Pathway Commons Protein-Protein Interactions 1.0 null T3M10 CCLE Cell Line Gene CNV Profiles -1.0 -2.24904 dorsal part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06541 H3K27ac_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7516_KO_TFAM_SRP213924 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.11083 superficial gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59833 H3K27ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EIF4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30403 dorsal part of m1A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19007 GCIY GDSC Cell Line Gene Expression Profiles 1.0 2.51361 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null BRD-K81795824_-666_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-UPIC-0002-SM-3NMDC GTEx Tissue Sample Gene Expression Profiles 1.0 1.19333 SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCT5 Pathway Commons Protein-Protein Interactions 1.0 null CYP3A5 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00678249 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_13947_KO_CAMTA1_SRP379121 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CTCF_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.856022 BRD-K09328667 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04934 HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01848 IGF2BP2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-SUCS-0926-SM-4DM4Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.930049 KPNA2 Pathway Commons Protein-Protein Interactions 1.0 null fusaric acid-1308 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null colonrectum_a HPA Tissue Sample Gene Expression Profiles 1.0 0.83859 GTEX-UTHO-0011-R2A-SM-3GIKC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.74228 H2AK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K58219783 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22341 mitochondrial part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.582176 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.052897 ARL8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23974 TUFM Pathway Commons Protein-Protein Interactions 1.0 null BRD-K22011492 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32157 BRD-K57080016_selumetinib_HEPG2_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4418-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM185PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.52598 DHRS2 Pathway Commons Protein-Protein Interactions 1.0 null MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.785011 SLC3A2 Pathway Commons Protein-Protein Interactions 1.0 null RPS29 Pathway Commons Protein-Protein Interactions 1.0 null DPYD LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00559009 IST-SL1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.14913 GSE70499_3_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.51435 Lung squamous cell carcinoma_LUSC_TCGA-66-2778-01A-02R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K69775722 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16809 GSE110440_1_v_0_rad21_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K30812092 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13028 striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.873522 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK1 ENCODE Transcription Factor Targets 1.0 null BRD-K42987166 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.24682 POLR2A_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC3470785-NIHMS377161-supplement-3.pdf-216-ZFP64_ZFP64 Rummagene Transcription Factor Associations 2026 1.0 null RPL10 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ADD3 Pathway Commons Protein-Protein Interactions 1.0 null PSMD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.43269 BRD-K00337317_HY-11006_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LSM3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57789 BRD-K14681218 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23501 ELF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nuclear GeneRIF Biological Term Annotations 1.0 null BRD-K26603007 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0374 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.76013 s12 GeneRIF Biological Term Annotations 1.0 null XRN2-22483619-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZNF839 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03548 BRD-K31987278 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46508 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05951 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K12502280_TG101348_VCAP_24.0_h_11.1_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.82774 Perturb_735_KD_PAF1_SRP048744 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.18972 Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SART1 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCLAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K62459624_T5212475_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2C Pathway Commons Protein-Protein Interactions 1.0 null hecogenin-5818 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CCDC86 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SETDB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE200673,GSE200691_2_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.901083 GSE118794_5_v_1_zmynd8_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsofrontal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14471 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE70499_3_v_2_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null RPL24 Pathway Commons Protein-Protein Interactions 1.0 null NRF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K35711197 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29479 Perturb_12666_OE_GFP_SRP308919 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.29206 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09511 Perturb_14631_KD_MSI1/MSI2_SRP067129 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.5953 single-organism organelle organization GO Biological Process Annotations 2015 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.17199 H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PANC1 BioGPS Cell Line Gene Expression Profiles 1.0 1.78173 BRD-K00816476 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42201 BRD-K99214816 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08449 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BOC LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00674625 BRD-K11423211 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.95387 POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-0002-SM-3NM8K GTEx Tissue Sample Gene Expression Profiles 1.0 0.826656 dexverapamil-164 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.979801 H3K4me1_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_11726_KO_Ikka_SRP229998 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 TGW GDSC Cell Line Gene Expression Profiles -1.0 -2.15335 H4K20me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K33448511 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.19479 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K39566424 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1738 streptomycin-5837 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HL-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sitosterol-2912 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-XLM4-0011-R9A-SM-4AT45 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.911021 r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50983 BRD-K12184916_NVP-BEZ235_MCF10A_24_h_0.04_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K10748141 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.87658 YY1_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE211286_4_v_6_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null PUF60 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26674 Perturb_12195_KD_ERCC4_SRP310546 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GTEX-S4UY-0008-SM-3NM8H GTEx Tissue Sample Gene Expression Profiles 1.0 2.2736 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.47852 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.63776 RPS13 Pathway Commons Protein-Protein Interactions 1.0 null GSE201042_6_v_4_ptpmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AL-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7357_OE_RBFOX1_SRP307800 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.59936 SNRNP200 Pathway Commons Protein-Protein Interactions 1.0 null CHCHD1 Pathway Commons Protein-Protein Interactions 1.0 null H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PVOW-0011-R5A-SM-32PL7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.86649 EBF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8988_KD_HNRNPC_SRP329785 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Disease Progression HuGE Navigator Gene-Phenotype Associations 1.0 null CTCF_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null necrosis GeneRIF Biological Term Annotations 1.0 null BRD-A75409952_wortmannin_PC3_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SNMC-0008-SM-4DM5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.86638 CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SOX2-30713093-EPITHELIAL-HUMAN-TONGUE-SCC ChEA Transcription Factor Targets 2022 1.0 null eGFP-JUNB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null RPS18 Pathway Commons Protein-Protein Interactions 1.0 null TJP1 Pathway Commons Protein-Protein Interactions 1.0 null T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901807 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EB-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WYJK-1026-SM-3NM8W GTEx Tissue Sample Gene Expression Profiles 1.0 1.17242 PMC9691391-7945884.f3.pdf-89-ENSG00000175727_MLXIP Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GSK3B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00502075 RPL26 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03255 leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072072 ELF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neoplasms CTD Gene-Disease Associations 1.0 1.04276 MSC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00272 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null BRD-K45101864 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0082 Primary hematopoietic stem cells G-CSF-mobilized Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.979005 RPS15A Pathway Commons Protein-Protein Interactions 1.0 null GSE186005_1_v_2_klf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.965891 SOX2-18692474-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-XUJ4-0008-SM-4BOQI GTEx Tissue Sample Gene Expression Profiles 1.0 1.51391 BRD-K58214070_N-{3-[(2-Chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-X62O-0008-SM-46MU5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.71249 TCP1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K29571884 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.95905 GSE211226_1_v_0_sirpa_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32238 H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.65454 POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null CTCF_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG7-2326-SM-3GIKV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.870406 AKAP8 Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05144 BRD-K99532291_SPB02303_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null lateral septal nucleus, intermediate part, periventricular Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.3114 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.82028 GTEX-P44H-1126-SM-48TBU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10721 H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r6 part of spinal trigeminal nucleus, pars oralis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77747 H3K79me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3367_KO_H1_SRP234772 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.37696 RPL6 Pathway Commons Protein-Protein Interactions 1.0 null hemicholinium-5339 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null meteneprost-7504 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SUIT2_PANCREAS CCLE Cell Line Proteomics 1.0 2.51143 HIST1H1C Pathway Commons Protein-Protein Interactions 1.0 null Perturb_4265_KD_CHD7_SRP160423 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.3749 RBM3 Pathway Commons Protein-Protein Interactions 1.0 null thyroid gland HPA Tissue Gene Expression Profiles -1.0 -0.82656 ZNF787 Pathway Commons Protein-Protein Interactions 1.0 null NR3C1-23031785-PC12-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCIH2227 CCLE Cell Line Gene CNV Profiles 1.0 2.17501 TAF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null translational elongation GO Biological Process Annotations 2015 1.0 null SP4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K82399478 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25291 SNRPD1 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.825797 HMGB2 Pathway Commons Protein-Protein Interactions 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV504 CCLE Cell Line Gene CNV Profiles -1.0 -1.45759 abnormal mitochondrial physiology MGI Mouse Phenotype Associations 2023 1.0 null mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.95323 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.99534 MRPS9 Pathway Commons Protein-Protein Interactions 1.0 null single-organism cellular process GO Biological Process Annotations 2015 1.0 null Perturb_10395_KD_USP11_SRP200727 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.86994 Perturb_4885_KD_TP53_SRP131666 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.99063 CDK1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00525161 mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24814 LARS Pathway Commons Protein-Protein Interactions 1.0 null CTCF_cardiac muscle cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRSF11 Pathway Commons Protein-Protein Interactions 1.0 null single-organism metabolic process GO Biological Process Annotations 2015 1.0 null BRD-A60784279_-666_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null iproniazid-2125 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_GM12870_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mitochondrial metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.39 Malignant tumor of pancreas_saliva_GSE14245 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.28003 GSE201239_6_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TAF1_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null smoothmuscle_8b HPA Tissue Sample Gene Expression Profiles -1.0 -0.930075 TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FBL Pathway Commons Protein-Protein Interactions 1.0 null BRD-K60905390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05611 TAF7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE60691_2_v_3_glutamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null BRD-K20526256_HG-14-10-04_HT29_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null RMDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27036 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19179 Perturb_4823_KD_Chd4_SRP315519 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.1969 GSE165122_2_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null NANOG ChEA Transcription Factor Targets 1.0 null SNU-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881045 BRD-K12836153 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09189 BRD-K70533557 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19901 Liver Diseases CTD Gene-Disease Associations 1.0 1.12323 adrenalgland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.019 UBC Pathway Commons Protein-Protein Interactions 1.0 null ACSL4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00700289 G3BP2 Pathway Commons Protein-Protein Interactions 1.0 null CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T8EM-1626-SM-3DB7K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.93238 TRIM28_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_16648_KO_Tardbp_SRP201975 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.60718 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ELK1-19687146-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.73714 BRD-K17133642 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11219 tardbp_19910924_hek293e_lof_human_gpl570_gds3730 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.156549 BRD-K46824282 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11092 BRD-K38669793 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14608 BRD-K13566078_BMS-345541_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_1270_OE_Sirpa_SRP392190 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 BRD-K34977825 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25907 BRD-K77953978 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21543 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.159268 stratum pyramidale of rostral CA3 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.867273 SIN3A_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRL-0008-SM-3NB29 GTEx Tissue Sample Gene Expression Profiles 1.0 2.04171 cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K28040935_NCGC00241732-01_A375_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null (+/-)-catechin-3012 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_6215_KO_Hdac1_SRP227204 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.99436 HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPS17 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K32093012 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47171 CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.931554 Hypertrophy CTD Gene-Disease Associations 1.0 1.3827 H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K55940699 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2077 SP1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH661 CCLE Cell Line Gene CNV Profiles 1.0 1.85283 POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WHSC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRO-0011-R2A-SM-3NB1W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45399 STAT1-20625510-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K67602895 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07213 CBX3 ENCODE Transcription Factor Targets 1.0 null BRD-K36847650 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04489 rna binding GO Molecular Function Annotations 2015 1.0 null SUCLG1 Pathway Commons Protein-Protein Interactions 1.0 null VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.47521 ANXA2 Pathway Commons Protein-Protein Interactions 1.0 null DDX56 Pathway Commons Protein-Protein Interactions 1.0 null raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.08803 CTCF_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARRB1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K08427390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49733 HIST1H4F Pathway Commons Protein-Protein Interactions 1.0 null PNPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4963 BRD-K28247259 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10161 PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Auditory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.684 BRD-K20000640_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE148252_0_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null AEBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5729 RUNX1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ATF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPU-0011-R7A-SM-2XCAB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.65114 SP2 ENCODE Transcription Factor Targets 1.0 null Human - Fetal Development - L2 - Pancreas-Lymphoid cells HuBMAP Azimuth Cell Type Annotations 1.0 null TAL1-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-3197 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 NR0B1-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ3S-0126-SM-4BOO9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04879 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.41306 TALL-1 GDSC Cell Line Gene Expression Profiles -1.0 -1.66634 SGPL1 Pathway Commons Protein-Protein Interactions 1.0 null GSE144796_1_v_0_linagliptin_mouse RummaGEO Drug Perturbation Signatures 1.0 null PML_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054151 BRD-K79232672 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59984 NXF1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K55164454 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04171 Necrosis CTD Gene-Disease Associations 1.0 1.85221 vitamin c_homo sapiens_gpl570_gds3635 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.99555 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Leber hereditary optic neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.58 SHSYSY-RA BioGPS Cell Line Gene Expression Profiles -1.0 -1.82578 kidney_a HPA Tissue Sample Gene Expression Profiles 1.0 1.08224 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5109-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null kidney GTEx Tissue Gene Expression Profiles 1.0 1.24121 Lateral septal nucleus, caudal (caudodorsal) part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80779 FOS ENCODE Transcription Factor Targets 1.0 null FAM120A Pathway Commons Protein-Protein Interactions 1.0 null TARDBP Pathway Commons Protein-Protein Interactions 1.0 null BRD-K89093471_VU0418934-2_HCC515_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ZFP91 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29228 shock GeneRIF Biological Term Annotations 1.0 null Superior colliculus, motor related, intermediate gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20899 Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EIF3A Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7335_KD_TMEM119_SRP279053 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 SW 780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.14583 TCF7L2_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r3 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43089 inner ear disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.13585 YD15 CCLE Cell Line Gene CNV Profiles -1.0 -1.43101 BRD-K26904107 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.87461 blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062886 GTEX-R3RS-0008-SM-48FF1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.40023 GTEX-QEL4-0526-SM-3GIJ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24458 POLR1A Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC10800016-table_s5_20230913_ddad186.xlsx-FvsC_-_DUX4_II-Unnamed_1_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K78385490_-666_A375_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K78907873 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.04781 MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31141 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FCF1 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_HCT116_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle inner membrane GO Cellular Component Annotations 2023 1.0 null PRKG1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00589389 Perturb_7694_KD_SNRNP200_SRP364705 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K03618428_PP-110_JHUEM2_6.0_h_22.2_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null STAT3-24763339-IMN-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RUNX3 ENCODE Transcription Factor Targets 1.0 null NFPS DeepCoverMOA Drug Mechanisms of Action 1.0 0.27 PPARA-22158963-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K27ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GATA1_G1E-ER4_mm9_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K79me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03166 CHD7 ENCODE Transcription Factor Targets 1.0 null UHRF1 Pathway Commons Protein-Protein Interactions 1.0 null ELK4 ENCODE Transcription Factor Targets 1.0 null SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.923162 MXI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K99749624_S1003_PHH_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null rosiglitazone-1233 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null EXOSC5 Pathway Commons Protein-Protein Interactions 1.0 null RELA_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF4 ENCODE Transcription Factor Targets 1.0 null Sengers syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.348 BRD-K77519898 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.148 0198306-0000-7102 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-0940-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PML_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K52473839 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22777 GSE70499_5_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC6683136-41598_2019_47363_MOESM5_ESM.xlsx-GENE_SET-Negative_correlation_of_ZEB1_and_other_genes_ZEB1 Rummagene Transcription Factor Associations 2026 1.0 null GCIY CCLE Cell Line Gene Expression Profiles 1.0 1.39712 BRD-K22949587 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11356 SPI1-22790984-ERYTHROLEUKEMIA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SW1271_LUNG CCLE Cell Line Proteomics 1.0 2.01078 H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K20271744 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.66382 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K02087489 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1887 Perturb_2068_KD_BMAL1_SRP041298 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.80333 ribosomal subunit GO Cellular Component Annotations 2015 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10545 BRD-K60161601 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.91839 endometrium_8a HPA Tissue Sample Gene Expression Profiles -1.0 -1.50236 TSN Pathway Commons Protein-Protein Interactions 1.0 null BRD-K60127720 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16205 embryonic lethality prior to organogenesis MGI Mouse Phenotype Associations 2023 1.0 null BRD-K44908610 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48413 SND1 Pathway Commons Protein-Protein Interactions 1.0 null T cell_Brain_Human CellMarker Gene-Cell Type Associations 1.0 null ZFHX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14806 E2F6 ENCODE Transcription Factor Targets 1.0 null SARS-CoV_84Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.4972 medial habenular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18063 PMC6742760-41467_2019_12079_MOESM10_ESM.xlsx-Data_S8-Supplementary_Data_8_Target_genes_of_FOXA1-bound_enhancers_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null IRF4_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bidirectional GeneRIF Biological Term Annotations 1.0 null BRD-K50841342_PAC 1_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null colorectum TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-K12502280_TG101348_SKMEL1_6.0_h_11.1_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null carbenoxolone-3353 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null OV56_OVARY CCLE Cell Line Proteomics 1.0 4.2789 GTEX-NPJ7-2826-SM-2I3FU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.921667 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H4K20me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 3.24385 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40881 BRD-A57300602_NP-009265_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null 16207250-TableS2 GeneSigDB Published Gene Signatures 1.0 null velnacrine-2430 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRSF3 Pathway Commons Protein-Protein Interactions 1.0 null KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.07717 amygdaloid complex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.85934 hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10823 Weight Gain CTD Gene-Disease Associations 1.0 1.06333 Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J2-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K99545815_PF-562271_LNCAP_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_9717_KD_Basp1_SRP126738 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.99667 ATP5H Pathway Commons Protein-Protein Interactions 1.0 null ML-2 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.38103 BRD-K39192716 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18088 PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA Rummagene Transcription Factor Associations 2026 1.0 null acute lymphoblastic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.515317 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5092 BRD-K31250130 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.01019 Superior colliculus, zonal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.57886 SCA1_Knock-in_GDS1756_233_mouse_Forebrain tissue - 4 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-WRHU-0626-SM-3MJFI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.843064 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K95359959 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71143 BRD-K44936922 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24656 GTEX-WHPG-2326-SM-3NMBP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855872 BRD-K37262314 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50712 BRD-K63920153 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15434 BRD-K20142115 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4359 H3K18ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A4MW-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.04247 TBP ENCODE Transcription Factor Targets 1.0 null GTEX-UTHO-0011-R5A-SM-3GIJD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01499 CTCF_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELAVL1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K79090631_CGP-60474_LNCAP_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null GSE231648_1_v_2_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_6488_OE_circAKT3_SRP216548 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 r3 part of spinal trigeminal sensory column, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53615 STAT3 ChEA Transcription Factor Targets 1.0 null PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-5_names_TP53 Rummagene Transcription Factor Associations 2026 1.0 null OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.828322 thyroid_5d HPA Tissue Sample Gene Expression Profiles -1.0 -0.986663 NANOG-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null genistein-1235 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE88819_5_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TBP_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QCQG-0526-SM-48U2A GTEx Tissue Sample Gene Expression Profiles 1.0 0.909223 CTCF_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K74710236_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PMC6724602-mbc-30-1272-s007.xlsx-EGR1_Binding_Sites-Unnamed_1_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null Accessory facial motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73429 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2856-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EIF4E Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6419_KD_PTPRN_SRP322005 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 BRD-K30772101 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1945 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.63605 CTCF_BE2C_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K37213205 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08271 GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.880049 BRD-K13662825_dinaciclib_A549_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Hypertrophic cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.169 mantle zone of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61804 BRD-K37865504_LY-2183240_PL21_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Mitochondrial translation initiation Reactome Pathways 2014 1.0 null GTEX-U3ZM-0002-SM-3NMDM GTEx Tissue Sample Gene Expression Profiles 1.0 1.22531 TMEM267 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13827 TPM3 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K91421454 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25823 CTCF_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41932 ITPRIPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42477 GTEx AdiposeTissue 20-29 vs 30-39 GTEx Tissue-Specific Aging Signatures -1.0 -5.65028 H4K20me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H4K20me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null ribosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 mitochondrial matrix COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 XAB2 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FHOD1 Pathway Commons Protein-Protein Interactions 1.0 null Leydig precursor cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ACHE LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00563206 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16678 BRD-K63778487 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03754 MEG01 CCLE Cell Line Gene Expression Profiles 1.0 1.54623 BRD-K75038426 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83783 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.38454 Perturb_2385_KO_ASXL2_SRP333775 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.83693 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cervical adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.161043 CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.133 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null BRD-K63425657_NP-010914_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K65824451 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05143 COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.2047 GABPA_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS255T CCLE Cell Line Gene Expression Profiles -1.0 -1.95646 GSE102757_1_v_0_panobinostat_mouse RummaGEO Drug Perturbation Signatures 1.0 null CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null colonrectum_d HPA Tissue Sample Gene Expression Profiles 1.0 0.885695 CDH11 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00638081 GSE95826_4_v_1_tcra_mouse RummaGEO Gene Perturbation Signatures 1.0 null KAT2A ENCODE Transcription Factor Targets 1.0 null positive regulation of Wnt signaling pathway GO Biological Process Annotations 2023 1.0 null Perturb_9401_KD_MYCN_SRP104120 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.96648 GTEX-P4QT-1426-SM-3NMCX GTEx Tissue Sample Gene Expression Profiles 1.0 0.825479 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO201 CCLE Cell Line Gene Expression Profiles 1.0 1.44366 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mitochondrial part GO Cellular Component Annotations 2015 1.0 null BRD-K13566078_BMS-345541_A549_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K40175214_torin-1_HME1_3_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19757 CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBX5-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PBX3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPS7 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-N7MS-0007-SM-2D7W1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44672 Perturb_6706_KD_ELOA_SRP314942 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.6671 GTEX-UPK5-1826-SM-3GAEB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.831984 BRD-K08659289 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67443 scopoletin-3131 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TE-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_GM12892_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K70876639 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59525 GSE195743_1_v_4_lhx6_mouse RummaGEO Gene Perturbation Signatures 1.0 null HNRNPAB Pathway Commons Protein-Protein Interactions 1.0 null IDH1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00612726 HGC27 CCLE Cell Line Gene CNV Profiles -1.0 -1.56218 H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HP1BP3 Pathway Commons Protein-Protein Interactions 1.0 null Hypertension_Adrenal gland_GSE1674 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.33433 Human - Tonsil - L1 - Naive CD8 T HuBMAP Azimuth Cell Type Annotations 1.0 null flupentixol-5307 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_18447_KD_H2AZ2_SRP199104 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.50561 JNK_KO_GDS3001_531_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsp60 GeneRIF Biological Term Annotations 1.0 null ABT1 Pathway Commons Protein-Protein Interactions 1.0 null GATA3-26560356-CHIP-SEQ-TH1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00558 GTEX-XBEW-0008-SM-4AT3Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.16261 TIAL1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K91905575 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71144 Perturb_58_KO_Gadd45a/Gadd45b_SRP187210 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.66341 GATA1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVN-0008-SM-48U2D GTEx Tissue Sample Gene Expression Profiles 1.0 1.42814 iopamidol-2732 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null cytoplasmic part GO Cellular Component Annotations 2015 1.0 null LRPPRC Pathway Commons Protein-Protein Interactions 1.0 null BRD-K78642007 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2975 PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null PML_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MC-IXC GDSC Cell Line Gene Expression Profiles 1.0 1.61247 BRD-K19894101_MST- 312_VCAP_24.0_h_11.1_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CREB1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.926898 BRD-K13068347 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14645 HSD17B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29016 MTF2-20144788-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K00218068 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4584 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37193 CTCF_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2998 BioGPS Cell Line Gene Expression Profiles 1.0 0.847237 Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TBP_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBM19 Pathway Commons Protein-Protein Interactions 1.0 null Neonatal period electroclinical syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.173 Skin BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.09016 AGTR2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00465649 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K09106444 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.66317 trap1 GeneRIF Biological Term Annotations 1.0 null DDX54 Pathway Commons Protein-Protein Interactions 1.0 null Ulcerative Colitis_Peripheral blood mononuclear cell_GSE3365 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.52555 CDC5L Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12792 Perturb_7552_OE_IL1RN_SRP300901 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.64283 BRD-K04611090 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50193 RNMT Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.824262 Microglial cell_Brain_Human CellMarker Gene-Cell Type Associations 1.0 null ESET-19884257-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null LUC7L Pathway Commons Protein-Protein Interactions 1.0 null BRD-K45717258 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51668 FOS_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r8 part of linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.10078 Perturb_12198_KD_XPA_SRP310546 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865367 HSPA1B Pathway Commons Protein-Protein Interactions 1.0 null BRD-K14193598 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06731 MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMK1-0001-SM-4B64F GTEx Tissue Sample Gene Expression Profiles 1.0 1.04825 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COLO-668 GDSC Cell Line Gene Expression Profiles -1.0 -2.3079 UTP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01514 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14615 BRD-K38273742 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2951 DNAH1 Pathway Commons Protein-Protein Interactions 1.0 null striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05573 pyrantel-1413 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null gliquidone-7301 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null uterus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.446422 GTEX-T5JW-0003-SM-3NMAD GTEx Tissue Sample Gene Expression Profiles 1.0 1.00797 NRF1 Pathway Commons Protein-Protein Interactions 1.0 null regulated GeneRIF Biological Term Annotations 1.0 null PPP1CA LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00435406 FAM181B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03249 rosiglitazone-6992 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null IRAK2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00501742 GTEX-XUW1-0726-SM-4BOP5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.935555 PBX3 ENCODE Transcription Factor Targets 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K31602464 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5022 NPC1L1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00447385 arsenic trioxide CTD Gene-Chemical Interactions 1.0 null abducens nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23674 GTEX-T6MO-0003-SM-3NMAG GTEx Tissue Sample Gene Expression Profiles 1.0 1.23336 PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR Rummagene Transcription Factor Associations 2026 1.0 null BRD-K21771449 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.93258 H3K4me1_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_11212_KO_Cd36_SRP351120 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.39498 AP2M1 MSigDB Cancer Gene Co-expression Modules 1.0 null H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43269 CREB1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNRNPA3 Pathway Commons Protein-Protein Interactions 1.0 null OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52114 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE203158_1_v_15_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null ribosomal small subunit biogenesis GO Biological Process Annotations 2023 1.0 null medial subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0193 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049638 CTCF_GM12801_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK4 JASPAR Predicted Transcription Factor Targets 1.0 null FLI1-21867929-CD8-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RPUSD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18911 BRD-A31576716 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23417 Perturb_951_KO_Suz12_SRP322809 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -13.8954 dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.921806 CREB1-15753290-HEK293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null YY1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44142 RBM10 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K74540252 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20488 Fetal Growth Retardation CTD Gene-Disease Associations 1.0 1.43455 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GTEX-UTHO-0726-SM-3GAEN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3718 NAT10 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4881_KD_TP53_SRP131666 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.6182 H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K10571700 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0943 LARP4 Pathway Commons Protein-Protein Interactions 1.0 null Mitochondrial translation termination Reactome Pathways 2014 1.0 null cefaclor-6622 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-WHSE-0926-SM-3NMBS GTEx Tissue Sample Gene Expression Profiles 1.0 0.983949 MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK1-22589737-MCF10A-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LLPH Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8845_KD_PPARGC1B_SRP254908 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08238 CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DCAF12L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05593 CTCF_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9341507-supp_gr.266924.120_Supplemental_Table_S4.xlsx-A_Jurkat_essential-MYB_MYB Rummagene Transcription Factor Associations 2026 1.0 null intermediate stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1011 PMC9585487-NIHMS1838959-supplement-4.xlsx-Upregulated-Table_S3_FOXC1_regulated_genes_FOXC1 Rummagene Transcription Factor Associations 2026 1.0 null organellar ribosome GO Cellular Component Annotations 2015 1.0 null medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73752 MARCKS Pathway Commons Protein-Protein Interactions 1.0 null SLC25A20 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00554145 CTCF_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE247862,GSE247863_0_v_1_eomes_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_3221_OE_Csf1_SRP265786 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.44923 intermediate stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43576 GTEX-PLZ6-0008-SM-48TD5 GTEx Tissue Sample Gene Expression Profiles 1.0 2.83724 BRD-K78385490_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K29415052_NVP-BGT226_HT29_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null IGF2BP1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_2678_Mut_STAT5A_SRP303606 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.70452 GTEX-RNOR-0011-R9A-SM-2TF52 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2621 PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4A-Down_Nanog_KD-Unnamed_1_AR Rummagene Transcription Factor Associations 2026 1.0 null preferentially GeneRIF Biological Term Annotations 1.0 null POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null methotrexate_homo sapiens_gpl570_gse11440 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null vorinostat_homo sapiens_gpl10558_gse35242 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null LONP1 Pathway Commons Protein-Protein Interactions 1.0 null TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 4.86313 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3F3A Pathway Commons Protein-Protein Interactions 1.0 null GTEX-UPK5-0003-SM-3NMDI GTEx Tissue Sample Gene Expression Profiles 1.0 0.873379 GSE185944_5_v_1_pth1r_mouse RummaGEO Gene Perturbation Signatures -1.0 null CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE123372,GSE123373_1_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K69406317_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_10770_KO_Jnk1/Jnk2_SRP038635 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.63971 GSE199874_4_v_5_gabpb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE203308_14_v_3_brf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32042 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.891507 NOP16 Pathway Commons Protein-Protein Interactions 1.0 null Kidney - Medulla GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.19894 mitochondrial translational initiation GO Biological Process Annotations 2015 1.0 null GSE237426_0_v_1_eif4a1_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.93051 BRD-K52669647 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02562 CTCF_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8434_KD_CCT3_ERP124101 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.0246 BRD-K26217579 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30043 Perturb_9305_KO_Med16_SRP295417 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 NANOG-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.6902 PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3 Rummagene Transcription Factor Associations 2026 1.0 null TCFCP2L1-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null structural constituent of ribosome GO Molecular Function Annotations 2015 1.0 null organelle inner membrane GO Cellular Component Annotations 2015 1.0 null BRD-K64567083 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20456 FUBP3 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K03618428_PP-110_HT29_6.0_h_22.2_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H2BK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MYBL2-22936984-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BRD-K92571446_WZ-3105_MCF10A_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null another GeneRIF Biological Term Annotations 1.0 null BRD-K33710385 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18787 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S4P3-0008-SM-3NM8R GTEx Tissue Sample Gene Expression Profiles 1.0 1.2693 anteroventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01168 TRIM28 Pathway Commons Protein-Protein Interactions 1.0 null H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 19843711-TableS1 GeneSigDB Published Gene Signatures 1.0 null ursolic acid-5825 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24429 Superior colliculus, superficial gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.11016 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null IMP3 Pathway Commons Protein-Protein Interactions 1.0 null mitochondrial membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.128344 H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRCA1 ENCODE Transcription Factor Targets 1.0 null H3K4me1_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K69932463_AZD8055_HT29_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null roof plate of p2 (epithalamic roofplate) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68642 H3K9ac_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EP300_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12871_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12866_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Perturb_372_KD_STING1_SRP350677 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 BRD-K64804596 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.87155 BRD-K11610091 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52623 PBXIP1 Pathway Commons Protein-Protein Interactions 1.0 null esculin-5411 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CHAF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02162 Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRMT2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00585505 BRD-K87602457 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02444 SYNE1 Pathway Commons Protein-Protein Interactions 1.0 null GSE218907_3_v_2_opa1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K14570970 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.64902 BRD-K29560103 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31121 Perturb_3443_KO_Acsl6_SRP321472 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.27012 GSE201239_3_v_2_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null RPS25 Pathway Commons Protein-Protein Interactions 1.0 null RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PDE8A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00410805 serotonin-2449 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.22662 SMU1 Pathway Commons Protein-Protein Interactions 1.0 null UBTF ENCODE Transcription Factor Targets 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.42597 NCAPD3 Pathway Commons Protein-Protein Interactions 1.0 null DDX1 Pathway Commons Protein-Protein Interactions 1.0 null S100A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07584 H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null gene expression GO Biological Process Annotations 2023 1.0 null Acne_Sebocyte_GSE10432 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.72212 HS 839.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.956306 MYOG_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.093513 SMURF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02338 H3K4me3_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HEXIM1 Pathway Commons Protein-Protein Interactions 1.0 null FFAR1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00416979 cell part LOCATE Curated Protein Localization Annotations 1.0 null BRD-K99545815_PF-562271_HA1E_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null FOXP3 ChEA Transcription Factor Targets 1.0 null NAP1L1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3645_KO_EP300_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.36888 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K58479490_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MHHES1 CCLE Cell Line Gene Expression Profiles -1.0 -1.83569 benzonatate-1843 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-SJXC-0326-SM-2XCFI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2944 mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.827519 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49312 ribosome GO Cellular Component Annotations 2015 1.0 null BRD-K34541722 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39846 YY1-26981420-C2C12-MOUSE-MUSCLE ChEA Transcription Factor Targets 2022 1.0 null RBM12 Pathway Commons Protein-Protein Interactions 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21382 GSE120595_5_v_4_arid2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_8013_KD_Chd1_SRP090682 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.82499 Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null liver TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_14844_KO_Emp2_SRP075761 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.59985 BRD-K65875972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05791 YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CP in retrosplenial cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00429 SNU1077 CCLE Cell Line Gene CNV Profiles 1.0 1.3349 LLGL2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9306_KO_Gsk3b_SRP295417 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 NARP syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.309 intracellular non-membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12868_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO-800 GDSC Cell Line Gene Expression Profiles -1.0 -1.47459 GTEX-S7SF-0008-SM-3NM8T GTEx Tissue Sample Gene Expression Profiles 1.0 2.46115 EIF2S2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Nucleus of the optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35576 MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXM1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K28392481_AZD4547_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null macromolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 SP2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PANC1 CCLE Cell Line Gene Expression Profiles 1.0 2.3325 MRPS26 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K73834056 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36149 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A50E-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC39A13_Deficiency_GDS3485_570_mouse_Chondrocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRPS31 Pathway Commons Protein-Protein Interactions 1.0 null cervical cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.128964 amoxicillin_rattus norvegicus_gpl341_colon_gds1273 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TRMT2A Pathway Commons Protein-Protein Interactions 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41589 GSE120595_0_v_4_arid2_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K34595616 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4613 Perturb_17650_KD_AFF4_SRP334520 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.70832 colon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-K76508844 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0812 LTB LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00785116 GTEX-PVOW-0626-SM-2XCF6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829518 BRD-K38633800 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.73902 BRD-K82638914 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.04102 iohexol-3322 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TLX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3739 cytosolic ribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.627761 BRD-A17687311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72798 HCC1500 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.597837 USF1_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null substantia nigra, pars compacta, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16789 BRD-K34489277 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80096 CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superior periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02799 TAL1-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 BRD-K35671498 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02665 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052429 HDLBP Pathway Commons Protein-Protein Interactions 1.0 null PRPF3 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K42671261 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.77845 SF539 BioGPS Cell Line Gene Expression Profiles 1.0 1.24153 GTEX-PVOW-0726-SM-2XCF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.87214 CTCF_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DNAJC9 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9085_KO_YAP_SRP297717 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 BRD-K04887706_Akti-1/2_VCAP_6.0_h_9.1_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.866343 VDR-24763502-THP-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null hexylcaine-6244 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null OCUB-M GDSC Cell Line Gene Expression Profiles 1.0 1.45683 MYC ChEA Transcription Factor Targets 1.0 null BRD-K87926172 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06589 GSE60691_2_v_1_glutamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null diazoxide-1368 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TFAM Pathway Commons Protein-Protein Interactions 1.0 null BRD-K04531886 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21917 Perturb_8914_KO_KDM1A_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.19238 Linear nucleus of the medulla Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15822 MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null ELF1 ENCODE Transcription Factor Targets 1.0 null PBX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0011-R9A-SM-32QOZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.69444 BRD-A75409952_wortmannin_VCAP_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ZC3H14 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K94962273 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07703 PF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00814 PAPLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03525 TAF1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K32127177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.74083 CTCF_GM12874_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_ZBTB12 Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_13165_KD_Myc_SRP057021 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.7959 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SCN5A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00487901 Supplemental somatosensory area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1093 H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null EVSAT CCLE Cell Line Gene Expression Profiles 1.0 1.40421 H3K4me1_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F2_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM19239_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NANOG-16518401-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K38694430 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05311 CTCF_GM12873_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Frontal pole, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17264 SP110 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00600253 temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.30519 BRD-K94452277 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32332 H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.06075 ChIP_DMAP1_20946988 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CCND1-20090754-RETINA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null macromolecular complex subunit organization GO Biological Process Annotations 2015 1.0 null ZC3H4 Pathway Commons Protein-Protein Interactions 1.0 null nitrofurantoin-2341 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD23A MSigDB Cancer Gene Co-expression Modules 1.0 null SIX5_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS27_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 2.02506 ERBB2_knockdown_233_GSE8373 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.69929 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77902 GTEX-OXRO-0011-R9A-SM-3NB1X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04617 GTEX-NL3H-0011-R7a-SM-2I3G5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14937 Perturb_3641_KO_BRD9_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.9689 RPS26 Pathway Commons Protein-Protein Interactions 1.0 null CCNT2 ENCODE Transcription Factor Targets 1.0 null RFC1 Pathway Commons Protein-Protein Interactions 1.0 null HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07922 GTEX-QMR6-0011-R4A-SM-32PKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04001 NCKIPSD LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00646529 GTEX-WFG8-0006-SM-3GIKS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39907 BRD-A79768653_sirolimus_VCAP_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-WL-A834-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EJM Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.60913 SOX11-22085726-ESNS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null LATS2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00640986 H3K4me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_symbol_that_KD_acts_upon_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-O5YT-0008-SM-4E3IQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.935308 hela cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.740503 RFX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MO-0726-SM-4DM58 GTEx Tissue Sample Gene Expression Profiles 1.0 0.950768 female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 BRD-K14139166 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02157 CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K47998973 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67066 GSE225141,GSE225143_2_v_3_mettl3_mouse RummaGEO Gene Perturbation Signatures -1.0 null SIX5 ENCODE Transcription Factor Targets 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null Perturb_15388_KD_PXN_SRP199372 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.40897 CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.875112 GTEX-POMQ-0006-SM-33HBY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41246 DECR1 Pathway Commons Protein-Protein Interactions 1.0 null Retrochiasmatic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09255 GSE239578_0_v_4_cxadr_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1 Rummagene Transcription Factor Associations 2026 1.0 null DYNLL1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00336633 H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K78438852 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58751 CTCF_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-0826-SM-2TF4S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41174 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05796 RBBP5 ENCODE Transcription Factor Targets 1.0 null MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.08005 HOXD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77068 POLR2A_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2B Pathway Commons Protein-Protein Interactions 1.0 null SERBP1 Pathway Commons Protein-Protein Interactions 1.0 null SNRPA1 Pathway Commons Protein-Protein Interactions 1.0 null BRCA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MELJUSO_SKIN CCLE Cell Line Proteomics 1.0 4.34399 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.885255 BRD-K31883758 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18268 REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null EEF1E1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K06718330 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.80352 intermediate stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23717 primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.942346 GTEX-PVOW-1026-SM-2XCF9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.951693 GTEX-TMMY-0008-SM-4DXU3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.33762 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7415-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTPLAD1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K06873288 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.21055 ELF1_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null reticular formation of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3502 Perturb_11506_KD_tsRNA5001a_SRP326669 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.15363 H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12875_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRPS12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11054 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R3-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DorsalRootGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.79665 Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC25A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84175 POLR2A_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE112761,GSE112767_4_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K60509482 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.10458 BRD-K93755725 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1864 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K12184916_NVP-BEZ235_MCF10A_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null orbital frontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08683 GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0864 GTEX-N7MT-0726-SM-3TW8S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845731 PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K91623615_ABT-751_PL21_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null POLR2A_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL21 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K49042040 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20479 SALL4_01_277 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60129 H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K85604751 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.89586 CEBPB_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ethambutol-1981 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COR-L321 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -1.70895 GTEX-S7PM-0006-SM-3NM8C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.998145 TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11084 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 ULK1_knockout_198_GSE60778 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.56295 BRD-K64606589_-666_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_339_KD_EIF4A1_SRP072285 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.93319 CTCF_astrocyte of the spinal cord_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 19965622-TableS2a GeneSigDB Published Gene Signatures 1.0 null SUP-B15 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.58647 RPL27A Pathway Commons Protein-Protein Interactions 1.0 null CVB3_30min-Infection_None_GSE697 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.599 RCOR1 ENCODE Transcription Factor Targets 1.0 null H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CREB1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null imatinib_homo sapiens_gpl96_gds3043 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null pioglitazone-5977 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ventrolateral prefrontal cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.833107 BRD-K99470595 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45484 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PRPF4B Pathway Commons Protein-Protein Interactions 1.0 null KDM4A ENCODE Transcription Factor Targets 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30655 ATIC Pathway Commons Protein-Protein Interactions 1.0 null VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24873 PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null PMC8101445-mbc-32-475-s003.xlsx-HEK_Tim29_KD-Gene_names_AR Rummagene Transcription Factor Associations 2026 1.0 null BRD-K30677119_PP-30_THP1_6.0_h_11.1_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SYK_druginhibition_286_GSE43510 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.43097 GSE229978_4_v_1_morphine_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE62843,GSE64371_4_v_3_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC2724271__F4 PFOCR Pathway Figure Associations 2024 1.0 null STAT1 ENCODE Transcription Factor Targets 1.0 null GTEX-V1D1-0008-SM-4JBIJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.56858 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42565 Blood Coagulation Disorders CTD Gene-Disease Associations 1.0 1.02933 Fibrosis CTD Gene-Disease Associations 1.0 1.08372 PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null GSE178255_1_v_7_tlr4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE224969,GSE224971_0_v_1_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89468 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3502 BRD-K14719962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.53149 GTEX-U8T8-0008-SM-4DXSP GTEx Tissue Sample Gene Expression Profiles 1.0 1.6645 mediodorsal nucleus of thalamus_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.939189 large intestine TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-K08259535 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.19271 GATA1_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1191_OE_CDYL_SRP335863 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 PMC11465086-mmc2.xlsx-Table_ES_1_markers_c0_LPS_Vs_Co-Gene_Expression_Data_1_markers_c0_LPS_Vs_Control_related_to_Figure_5_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.52274 DDX50 Pathway Commons Protein-Protein Interactions 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81721 COLO 800 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.01654 H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.6598 nucleoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.597276 GSE200673,GSE200691_1_v_3_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS2_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUDHL1 CCLE Cell Line Gene CNV Profiles 1.0 1.74121 cellular macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12201 RKN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71761 Perturb_13105_KO_Dnmt3l_SRP058459 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.75042 Lung squamous cell carcinoma_LUSC_TCGA-66-2766-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_15045_OE_FOXQ1_SRP319582 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.44822 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null SMRT-22465074-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.58998 HCFC1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RTLS-0426-SM-2TF5K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16162 POU5F1-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K71742655 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72935 D341MED CCLE Cell Line Gene Expression Profiles -1.0 -1.87705 H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FLI1 ENCODE Transcription Factor Targets 1.0 null BRD-K34688736 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04459 ventromedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30043 HADHA Pathway Commons Protein-Protein Interactions 1.0 null BRD-A23193246 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.72266 PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K53447551 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15129 EIF3E Pathway Commons Protein-Protein Interactions 1.0 null Perturb_4376_KD_CREBBP_SRP072506 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.40725 Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_72_KD_DNTM3B_SRP315598 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.53331 POLR2A_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNRNPDL Pathway Commons Protein-Protein Interactions 1.0 null BRD-K41707029 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58699 BRD-K21933068 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83269 GSE180800,GSE180801_0_v_5_tex10_mouse RummaGEO Gene Perturbation Signatures -1.0 null PML_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51631 CREB1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K57972271 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.87157 ChIP_PRDM14_21183938 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-RN64-0526-SM-2TC5P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13648 19334046-TableS3a GeneSigDB Published Gene Signatures 1.0 null HNRNPL Pathway Commons Protein-Protein Interactions 1.0 null H3K79me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5K3-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.21 GTEX-QMRM-0008-SM-447B1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56764 U2AF1 Pathway Commons Protein-Protein Interactions 1.0 null KNS-42 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K87909389_alvocidib_HME1_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPARG-20176806-3T3-L1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE149075_1_v_4_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null HT1376_URINARY_TRACT CCLE Cell Line Proteomics 1.0 2.52083 Kidney Diseases CTD Gene-Disease Associations 1.0 1.39591 H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null FLI1-21867929-TH2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF-21964334-BJAB-B-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-A68123879 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39545 DRG1 Pathway Commons Protein-Protein Interactions 1.0 null FARP1 Pathway Commons Protein-Protein Interactions 1.0 null dilated cardiomyopathy MGI Mouse Phenotype Associations 2023 1.0 null Perturb_2250_KO_Piezo1_SRP355856 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.39774 GTEX-SN8G-0526-SM-32PLE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33106 BRD-K00685640 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35212 viscus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null KLHDC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34691 H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 18310505-TableS7 GeneSigDB Published Gene Signatures 1.0 null UBA52 Pathway Commons Protein-Protein Interactions 1.0 null E2F4 ENCODE Transcription Factor Targets 1.0 null GABPA_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.202009 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null C-33 A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.14164 EIF4H Pathway Commons Protein-Protein Interactions 1.0 null FUOV1 CCLE Cell Line Gene CNV Profiles 1.0 1.71124 BRD-K10433727 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34756 DUS3L Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RTLS-0008-SM-48FET GTEx Tissue Sample Gene Expression Profiles 1.0 1.78024 PLA2R1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00579297 Perturb_1350_KD_NSUN2_SRP212699 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.699 BRD-A14098586 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31127 Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K95875837 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09523 Perturb_74_KO_POM121_SRP117164 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.01654 BRD-K00920341 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11313 BRD-K49010888_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.036 STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.26769 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K46056750_HY-10992_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HNRNPH1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K26194226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50796 POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null a549 HPA Cell Line Gene Expression Profiles 1.0 2.69231 H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mitochondrion organization GO Biological Process Annotations 2015 1.0 null CHD2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC Rummagene Transcription Factor Associations 2026 1.0 null NELFCD Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cervical carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.121968 SCLC21H CCLE Cell Line Gene Expression Profiles -1.0 -1.69904 BRD-K45112293 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.74899 BRD-K95048194 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63487 PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-V955-2426-SM-3GAEF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.937143 mitochondrial ribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.29103 MYBL2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PABPN1 Pathway Commons Protein-Protein Interactions 1.0 null HCFC1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EIPA DeepCoverMOA Drug Mechanisms of Action -1.0 -0.78 RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDT8-0426-SM-32PKZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.952836 Perturb_222_KO_Cebpd_SRP316336 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Lung adenocarcinoma_LUAD_TCGA-64-5781-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K86102179 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00007 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.34925 BRD-K72125659 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40577 MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM18526_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HSPA8 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.79445 Perturb_14678_KO_Prmt1_SRP153406 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 H3K79me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_1200_KO_Maz/Sp1_SRP302435 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 SNU601 CCLE Cell Line Gene CNV Profiles 1.0 1.38551 Perturb_16455_KO_CHUK_SRP229998 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GTEX-PWCY-2226-SM-2S1OP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07488 USF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62635 SARS-BatSRBD_0Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.38507 PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-hgnc_symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19919 Vomiting CTD Gene-Disease Associations 1.0 1.02783 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.927955 NCOA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11489 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.14473 GTEX-Q2AG-0008-SM-48U2K GTEx Tissue Sample Gene Expression Profiles 1.0 2.88474 MYC-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BRD-K05411364 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68952 Perturb_7620_OE_OspC3_SRP368098 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.80314 mcf7 HPA Cell Line Gene Expression Profiles 1.0 0.91458 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.9607 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null positive regulation of canonical Wnt signaling pathway GO Biological Process Annotations 2023 1.0 null Perturb_1443_KO_Cd18_SRP376289 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.85522 biosynthetic process GO Biological Process Annotations 2015 1.0 null H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04914 NARS Pathway Commons Protein-Protein Interactions 1.0 null HCFC1 ENCODE Transcription Factor Targets 1.0 null GSE63048_11_v_8_morc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null intracellular organelle lumen COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 BRD-K04443775 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14917 GTEX-R55G-2326-SM-2TC61 GTEx Tissue Sample Gene Expression Profiles 1.0 1.68317 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K50068274 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14546 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.14655 PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_9828_KD_CRNKL1_SRP245546 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.19405 lomefloxacin-3620 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K20690715 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.8864 HIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39327 BRD-U29336476_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K58017833 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33901 dorsal part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91948 BRD-K90526956 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24536 NELFE_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.838736 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K78818514 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2134 H3K36me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4777381-pone.0150624.s007.xlsx-dif_exp_AD-ZBTB38_ZBTB38 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K50291875 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30229 ELK4_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EW-13 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.437 BRD-K29756429 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07678 BRD-K94915822 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12946 E2F6_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.938596 GTEX-W5WG-2226-SM-4LMI3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.86262 BRD-K53308430_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Ribosomal protein S12, bacteria InterPro Predicted Protein Domain Annotations 1.0 null HARS2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_15968_KO_Gata3_SRP357829 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.82516 BRD-K75637705 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01833 PHF8 ENCODE Transcription Factor Targets 1.0 null GTEX-XUZC-0726-SM-4BOPH GTEx Tissue Sample Gene Expression Profiles 1.0 0.923589 GSE172295_0_v_2_sh3gl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null A549 CCLE Cell Line Gene CNV Profiles 1.0 1.56356 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K99038919 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13597 CEBPZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterior cingulate area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15662 FUBP1 Pathway Commons Protein-Protein Interactions 1.0 null PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null KLF4-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K07005393_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Posterior pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77304 NCL Pathway Commons Protein-Protein Interactions 1.0 null BRD-K76907295_VU0418947-2_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null EPB41L1 Pathway Commons Protein-Protein Interactions 1.0 null YY1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_KLF4_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Perturb_4584_KO_Socs3_SRP099234 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.42213 SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K77480336_-666_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null superficial stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07072 Perturb_3336_KO_Chaf1b_SRP258035 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.8255 posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.67845 EFTUD2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ME2 Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.861139 SDAD1 Pathway Commons Protein-Protein Interactions 1.0 null APEX1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-A36630025_-666_VCAP_24.0_h_0.35_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K79me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K64663625 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07822 BRD-K91225366 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.04293 CTCF_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null BMS1 Pathway Commons Protein-Protein Interactions 1.0 null TRIM28_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PLCD3 Pathway Commons Protein-Protein Interactions 1.0 null increased cholesterol level MGI Mouse Phenotype Associations 2023 1.0 null GSE203158_5_v_15_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51503 BRD-K13551202 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18568 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3-18555785-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null protein complex subunit organization GO Biological Process Annotations 2015 1.0 null BCLAF1 Pathway Commons Protein-Protein Interactions 1.0 null POLR2AphosphoS5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 12907009-SuppTable GeneSigDB Published Gene Signatures 1.0 null GTEX-XQ3S-0626-SM-4BOOB GTEx Tissue Sample Gene Expression Profiles 1.0 1.28649 BRD-K02675272 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11381 ZNF263 ENCODE Transcription Factor Targets 1.0 null RPS2 Pathway Commons Protein-Protein Interactions 1.0 null periventricular stratum of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30715 Superior colliculus, optic layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.58757 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K23282736_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null KLHL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18078 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.26649 BRD-K98276754 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23897 Perturb_12166_KO_TRAM2_SRP254106 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.08477 NF2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00591143 FBXW7 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00719117 Perturb_10361_KO_Arid5a_SRP288358 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.03241 ribosomal subunit COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37569 BRD-K48113764 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29443 BRD-K21119095 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.78473 Mitochondrial DNA depletion syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.381 PTGER3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00541515 CTCF_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRPS15 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U4B1-1126-SM-4DXV3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04801 bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.39128 IK Pathway Commons Protein-Protein Interactions 1.0 null CTCF_fibroblast of foreskin _hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRSF2 Pathway Commons Protein-Protein Interactions 1.0 null upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.96162 Perturb_5283_Mut_Tet2_SRP111192 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.51497 HNRNPLL Pathway Commons Protein-Protein Interactions 1.0 null DPY30 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K49371609_528116.cdx_SW480_6.0_h_0.09_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K26051127 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17455 carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.273346 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8355885-gutjnl-2020-320652supp004.xlsx-RALY_KD_mRNA-seq-Table_3_RALY_Knockdown_in_HCT116_cells_mRNA-seq_log2_FC_1_AR Rummagene Transcription Factor Associations 2026 1.0 null t69-brown-adipose_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.69234 ribonucleoprotein complex GO Cellular Component Annotations 2015 1.0 null GTEX-TKQ1-0008-SM-4DXSO GTEx Tissue Sample Gene Expression Profiles 1.0 2.1304 NCIH1573 CCLE Cell Line Gene CNV Profiles -1.0 -1.47083 SRSF6 Pathway Commons Protein-Protein Interactions 1.0 null PRMT1 Pathway Commons Protein-Protein Interactions 1.0 null H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Pruritus CTD Gene-Disease Associations 1.0 1.10033 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K09499853_KU 0060648 trihydrochloride_U937_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HT29 BioGPS Cell Line Gene Expression Profiles 1.0 1.45713 HCC1599 CCLE Cell Line Gene Expression Profiles 1.0 1.5846 ELF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K36539857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07745 cytosolic small ribosomal subunit GO Cellular Component Annotations 2023 1.0 null CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNRNPC Pathway Commons Protein-Protein Interactions 1.0 null BRD-K81522725 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.73138 GSE62843,GSE64371_2_v_5_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-O5YV-1126-SM-3LK73 GTEx Tissue Sample Gene Expression Profiles 1.0 1.70623 Lung squamous cell carcinoma_LUSC_TCGA-33-4532-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K15426523 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.74217 HUH-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null YY1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null DAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45018 Adrenal Gland GTEx Tissue Gene Expression Profiles 2023 1.0 1.31537 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null SCAF4 Pathway Commons Protein-Protein Interactions 1.0 null Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null estradiol_homo sapiens_gpl570_gse23610 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.17827 RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE183251_4_v_6_cyp2c70_mouse RummaGEO Gene Perturbation Signatures -1.0 null cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.5134 GSE215351,GSE215794_7_v_0_kdm8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTF3C4 Pathway Commons Protein-Protein Interactions 1.0 null CD59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26603 SIN3A ENCODE Transcription Factor Targets 1.0 null BRD-K12184916_NVP-BEZ235_MCF10A_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30753 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_HEK293_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.551425 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1299 CCLE Cell Line Gene CNV Profiles 1.0 1.50477 BRD-K20836550 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50245 GTEX-RM2N-0126-SM-48FDD GTEx Tissue Sample Gene Expression Profiles 1.0 0.861931 ATF2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7PM-0011-R5A-SM-3NM8G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08136 TUBB Pathway Commons Protein-Protein Interactions 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null nes HPA Cell Line Gene Expression Profiles -1.0 -2.39799 Leydig cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null Perturb_10137_KD_IIRX_SRP162384 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.7812 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null FOXA2 ENCODE Transcription Factor Targets 1.0 null HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29219 BRD-K09499853_KU 0060648 trihydrochloride_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null estradiol_mus musculus_gpl7509_gse14774 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-XMD1-0011-R2B-SM-4AT5N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.922364 PMC7423359-abb8771_Table_S4.xlsx-Sheet1-Genes_detected_at_least_twice_in_h4E_BP1-hyperTRIBE_711_genes_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null DDX3X Pathway Commons Protein-Protein Interactions 1.0 null CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08022 TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LYAR Pathway Commons Protein-Protein Interactions 1.0 null BRD-K45576113 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.44952 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GTEX-XBED-0003-SM-47JWP GTEx Tissue Sample Gene Expression Profiles 1.0 1.11763 BRD-K60870698_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CDK5_knockdown_99_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.755 CTCF_A549_hg19_10 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XXEK-0004-SM-4BRWO GTEx Tissue Sample Gene Expression Profiles 1.0 1.28823 PcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00096 EPRS Pathway Commons Protein-Protein Interactions 1.0 null NFE2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24919 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16555 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF774 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57395 RARA-24833708-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Anteroventral nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43234 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SMARCA4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00496647 H3K79me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRO-1926-SM-2S1O3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57174 GTEX-XOTO-0011-R9A-SM-4GICI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05119 BRD-K43674766 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.60592 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.05574 HCC1599 CCLE Cell Line Gene CNV Profiles 1.0 1.36202 H3K27ac_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null DHX9 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00673656 GTEX-VUSG-2626-SM-4KKZI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.941818 CTCF_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRPL12 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K80296876 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23799 Perturb_16647_KO_Tardbp_SRP201975 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 EZH2 ENCODE Transcription Factor Targets 1.0 null TNIP3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00535606 H3K4me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K50117485 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.85561 Lung squamous cell carcinoma_LUSC_TCGA-85-A510-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11985509-41467_2025_58704_MOESM7_ESM.xlsx-ZNF385A_vs_NES-Unnamed_1_ZNF385A Rummagene Transcription Factor Associations 2026 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.900783 BRD-A38030642_cyclosporine_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null RELA_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K30962012 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72169 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.26312 SYNCRIP Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10414_KO_ZFP91_SRP315744 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.2916 SLC25A3 Pathway Commons Protein-Protein Interactions 1.0 null HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.15262 CRMP1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12546_KO_Shank2_SRP309197 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.75827 Perturb_324_KD_BCAP31_SRP320890 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.60103 GTEX-PLZ5-0326-SM-3P614 GTEx Tissue Sample Gene Expression Profiles 1.0 0.893969 Perturb_340_KD_EIF4E_SRP072285 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.5972 BRD-K10649245_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K15879529 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30315 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.317456 BRD-K33805195 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5677 CTCF_GM12870_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC43A3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00458118 E2F1-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ILF2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948994 TAF1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K98169006 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.70078 GTEX-PLZ4-1326-SM-2S1O7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980609 scopolamine N-oxide-6335 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05402 H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K24143478 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48355 GTEX-QLQ7-0008-SM-447AW GTEx Tissue Sample Gene Expression Profiles 1.0 1.33838 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNRPA Pathway Commons Protein-Protein Interactions 1.0 null BRD-K07813434 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49934 induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14684 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MT-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.905206 POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.15206 TNFRSF18 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00674366 H3K4me1_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K50477983 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03917 RUNX2 JASPAR Predicted Transcription Factor Targets 1.0 null BRD-K79090631_CGP-60474_HME1_24_h_0.04_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PMC7339546-12915_2020_793_MOESM2_ESM.xlsx-Table_S12-Table_S12_common_twin_genes_in_one_HMR_core_region_between_cattle_and_human_NR4A1 Rummagene Transcription Factor Associations 2026 1.0 null E2F4-17652178-JURKAT-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cefalexin-1273 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Organelle biogenesis and maintenance Reactome Pathways 2014 1.0 null dorsolateral part of m1A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06007 TMA7 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00470198 YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K94441949 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29114 CTCF_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM229A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39444 BRD-K99127896 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07064 GNL3 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null auditory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.28086 RPS19BP1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12894_KD_IKZF3_SRP185722 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 LSM7 Pathway Commons Protein-Protein Interactions 1.0 null PLRG1 Pathway Commons Protein-Protein Interactions 1.0 null PMC6724602-mbc-30-1272-s007.xlsx-EGR1_Binding_Sites-Egr1_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null CPSF6 Pathway Commons Protein-Protein Interactions 1.0 null 16341039-TableS2 GeneSigDB Published Gene Signatures 1.0 null GTEX-X88G-0126-SM-47JZ3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.892767 SNRNP70 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9002_KD_TJP2_SRP306934 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HDAC1 MSigDB Cancer Gene Co-expression Modules 1.0 null mitochondrial ribosome GO Cellular Component Annotations 2023 1.0 null GSE132386_1_v_0_ppara_mouse RummaGEO Gene Perturbation Signatures -1.0 null AF4-28076791-SEM-HUMAN-BLOOD-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null GTEX-OXRN-0011-R5A-SM-2I5EF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39666 Perturb_8835_KO_RING1A_SRP345831 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46005 EBF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytosolic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.071221 Lung adenocarcinoma_LUAD_TCGA-55-A491-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4577_OE_Haspin_SRP271373 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.8432 HNRNPA2B1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K32280984 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67324 amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.10254 SF3B5 Pathway Commons Protein-Protein Interactions 1.0 null translation GO Biological Process Annotations 2023 1.0 null GTEX-UTHO-0011-R1A-SM-3GIJO GTEx Tissue Sample Gene Expression Profiles -1.0 -2.18753 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.853813 BRD-K49669041_BX-912_HEPG2_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Ventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26345 BRD-K84235037 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38855 Nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.681 TF1 CCLE Cell Line Gene Expression Profiles 1.0 1.98524 PMC7441006-41388_2020_1389_MOESM2_ESM.xlsx-Supplementary_Table_1-Prostate-Specific_MYC_Overexpression_MYC Rummagene Transcription Factor Associations 2026 1.0 null DHCR24 Pathway Commons Protein-Protein Interactions 1.0 null Anemia CTD Gene-Disease Associations 1.0 1.41035 GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -2.03702 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.970092 Medial pretectal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94315 KDM5A ENCODE Transcription Factor Targets 1.0 null GTEX-S4Q7-0008-SM-3NM8A GTEx Tissue Sample Gene Expression Profiles 1.0 0.938386 RMG-I GDSC Cell Line Gene Expression Profiles 1.0 1.57127 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null cytoplasmic part LOCATE Curated Protein Localization Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CFAP97 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35325 GABPA_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPJH-0001-SM-3NMDE GTEx Tissue Sample Gene Expression Profiles 1.0 1.41244 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08022 BRD-K74710236_-666_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Principal sensory nucleus of the trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16231 skin TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MRPL16 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K21025364_NVP-TAE226_HT29_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Prestwick-664-6033 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K68270916 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32375 GSE112761,GSE112767_1_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K20157822 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04309 BRD-K20526256_HG-14-10-04_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE120595_5_v_1_arid2_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K27248268 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47909 GTEX-WEY5-0008-SM-4LMKC GTEx Tissue Sample Gene Expression Profiles 1.0 1.04413 BRD-K35863275 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6783 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NOP14 Pathway Commons Protein-Protein Interactions 1.0 null REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 2.04088 H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PRKDC LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00674105 POLR2E Pathway Commons Protein-Protein Interactions 1.0 null GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -2.42804 Perturb_4865_KD_HERVH_ERP004298 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 todralazine-1677 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSTK1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00473815 SIX5_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null small ribosomal subunit COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FN1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X4XY-0011-R8A-SM-46MVC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.84345 Anterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51602 BRD-K86899078_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.931701 Septofimbrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52086 TCF12 ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABCA8 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00665667 Perturb_8837_KO_RBM12_SRP369839 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.83211 SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K85357344 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17334 NFIC_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K59930979 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27213 RPS24 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H2170 GDSC Cell Line Gene Expression Profiles 1.0 2.30242 EOMES-20176728-TSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_2075_KD_PUM1_SRP072710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE248858_5_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null many GeneRIF Biological Term Annotations 1.0 null Perturb_14689_KO_Ffar3_SRP057302 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.1739 sevoflurane_homo sapiens_gpl570_gds2772 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NUDT21 Pathway Commons Protein-Protein Interactions 1.0 null ZMIZ1 ENCODE Transcription Factor Targets 1.0 null E2F4_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13298 Perturb_6409_OE_ESR2_SRP165889 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.91594 HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NOA1 Pathway Commons Protein-Protein Interactions 1.0 null mitochondrial inner membrane GO Cellular Component Annotations 2023 1.0 null WRNIP1 ENCODE Transcription Factor Targets 1.0 null BRD-K38610362 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6678 NCI-H1963 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.62501 Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCT4 Pathway Commons Protein-Protein Interactions 1.0 null ATF3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LYL1 ChEA Transcription Factor Targets 1.0 null autosomal dominant nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.9267 Drug-Related Side Effects and Adverse Reactions CTD Gene-Disease Associations 1.0 1.10459 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null protein binding GO Molecular Function Annotations 2015 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.72492 USF1 ENCODE Transcription Factor Targets 1.0 null BRD-K30121969 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43716 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11926 Retrosplenial area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00096 GATA3-20176728-TSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1055_KD_LINC02015_SRP346389 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.39715 BRD-K40765512 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18815 procyclidine-2991 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MRPS23 Pathway Commons Protein-Protein Interactions 1.0 null MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null naringin-2425 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K79me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IRF3 ENCODE Transcription Factor Targets 1.0 null TOE1 Pathway Commons Protein-Protein Interactions 1.0 null LOUCY CCLE Cell Line Gene Expression Profiles -1.0 -1.53181 MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7217_KD_LAS1L_SRP321650 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 HNRNPR Pathway Commons Protein-Protein Interactions 1.0 null BRD-K74879991 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34724 HSPB8 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0045676 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A75409952_wortmannin_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null TRIM28 ENCODE Transcription Factor Targets 1.0 null NIHOVCAR3 CCLE Cell Line Gene Expression Profiles 1.0 2.07764 JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null UFL1 Pathway Commons Protein-Protein Interactions 1.0 null BRCA1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.867843 ovary HPA Tissue Protein Expression Profiles -1.0 -2.82113 BRD-K59708864 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.10429 CA12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12465 primary auditory cortex (core)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3798 BRD-K76215709 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16775 BRD-K93846199 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27605 decitabine_homo sapiens_gpl571_gse29077 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HuO-3N1 GDSC Cell Line Gene Expression Profiles -1.0 -1.74394 BRD-K85818861_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K76938712_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PEG3 Pathway Commons Protein-Protein Interactions 1.0 null Leukemia, Chronic T-Cell_T lymphocyte_GSE5788 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.69543 PPARGC1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55353 NCI-H1092 GDSC Cell Line Gene Expression Profiles -1.0 -2.71549 CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CPLANE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0252 mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.847363 ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K79090631_CGP-60474_A549_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K56ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null skbr3 HPA Cell Line Gene Expression Profiles 1.0 0.848547 hnrnpm4 GeneRIF Biological Term Annotations 1.0 null HDAC6 ENCODE Transcription Factor Targets 1.0 null POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K70856965 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64622 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.80561 r2 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3683 Lateral habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23286 gallbladder_5c HPA Tissue Sample Gene Expression Profiles -1.0 -1.65875 CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RFX5 ENCODE Transcription Factor Targets 1.0 null SIGLEC11 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00614232 GTEX-QCQG-1926-SM-2S1PI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.953534 striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.56045 ENTPD1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00525776 RAD21_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K09468701 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04895 H3K27ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FOXM1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.91369 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 20081105-ST-1 GeneSigDB Published Gene Signatures 1.0 null BRD-K79090631_CGP-60474_HME1_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MCFD2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00614616 Perturb_7485_OE_Mir489_SRP155560 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.1845 boldine-2148 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.16233 CCND1 ChEA Transcription Factor Targets 1.0 null disopyramide-7035 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K56653679_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-S7PM-0011-R6A-SM-3NM8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05286 IGF2BP3 Pathway Commons Protein-Protein Interactions 1.0 null SOX9-24532713-HFSC-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HNRNPH3 Pathway Commons Protein-Protein Interactions 1.0 null SFPQ Pathway Commons Protein-Protein Interactions 1.0 null CHD4 ENCODE Transcription Factor Targets 1.0 null JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A20697603_T8902_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_fibroblast of the aortic adventitia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DDX55 Pathway Commons Protein-Protein Interactions 1.0 null GRWD1 Pathway Commons Protein-Protein Interactions 1.0 null SU8686 CCLE Cell Line Gene CNV Profiles 1.0 2.71694 POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ2-0004-SM-3NMAC GTEx Tissue Sample Gene Expression Profiles 1.0 0.873754 superficial layers of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0778 NFYB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KARS Pathway Commons Protein-Protein Interactions 1.0 null KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.68046 PMC4777381-pone.0150624.s006.xlsx-dif_exp_AD-ZBTB38_ZBTB38 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XV7Q-0826-SM-4BRV7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02214 BHLHE40 ENCODE Transcription Factor Targets 1.0 null cellular_component LOCATE Curated Protein Localization Annotations 1.0 null TE159T CCLE Cell Line Gene Expression Profiles -1.0 -1.75299 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.169859 mitochondrial membrane GO Cellular Component Annotations 2023 1.0 null SPINK7 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_GM12872_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K28360340_TW 37_HCC515_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K79me2_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null IRF3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mrps12sarsm GeneRIF Biological Term Annotations 1.0 null SU-DHL-1 GDSC Cell Line Gene Expression Profiles 1.0 1.56477 SREK1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-UJMC-0008-SM-4IHKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.1737 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Movement Disorders CTD Gene-Disease Associations 1.0 1.02522 BRD-K86961579 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31395 SMARCC1 ENCODE Transcription Factor Targets 1.0 null GTEX-VUSG-0008-SM-4KL24 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45083 COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.49051 BRD-K57778236 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.037 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1365 MYC_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USP39 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U3ZH-1726-SM-3DB79 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08138 Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13481 GSE206270_1_v_0_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K73286847 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65961 NRF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K54107674 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30818 FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG8-0001-SM-4LVN8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.986102 DDX21 Pathway Commons Protein-Protein Interactions 1.0 null CCDC74B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16222 CELF1 Pathway Commons Protein-Protein Interactions 1.0 null NELFE ENCODE Transcription Factor Targets 1.0 null H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-POYW-0008-SM-48TE4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19433 BRD-K83972459_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null EHHADH Pathway Commons Protein-Protein Interactions 1.0 null PUS1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_13754_KD_KLF3_SRP233218 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.02155 GTEX-XQ3S-1126-SM-4BOPK GTEx Tissue Sample Gene Expression Profiles 1.0 1.33318 BRD-K87947369_VX-680_HT29_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-RVPU-0011-R1A-SM-2XCAI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59677 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCFL_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_17051_KO_Bcl11b_ERP105671 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.04127 HCC1482 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.87768 bicuculline-2139 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SP1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855656 GTEX-VUSG-1526-SM-4KKZH GTEx Tissue Sample Gene Expression Profiles 1.0 0.86389 RELA ENCODE Transcription Factor Targets 1.0 null GTEX-WH7G-0002-SM-4LVN9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35949 YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHPG-0004-SM-3NMDO GTEx Tissue Sample Gene Expression Profiles 1.0 0.939835 GTEX-S95S-0008-SM-4AT5M GTEx Tissue Sample Gene Expression Profiles 1.0 1.12292 TRIM66 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68566 POLR2A_Raji_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.8825 TET1-21451524-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZI-0626-SM-2XCEH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.87813 FLI1_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K88977610 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59245 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-0008-SM-4DM53 GTEx Tissue Sample Gene Expression Profiles 1.0 0.859596 BRD-K44497547 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0699 CTCF_fibroblast of villous mesenchyme_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68873 Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.37902 Neurologic Manifestations CTD Gene-Disease Associations 1.0 1.04978 GSE139239_2_v_5_ddr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE181821_1_v_4_mov10_mouse RummaGEO Gene Perturbation Signatures -1.0 null YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01848 CTCF_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YT-0126-SM-48TBW GTEx Tissue Sample Gene Expression Profiles 1.0 0.940238 GTEX-OHPN-0011-R7A-SM-2I5FI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14352 Perturb_9001_KD_KAT7_SRP174052 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 superficial stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53749 STAT3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterior cingulate area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24372 Perturb_12197_KD_ERCC6_SRP310546 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 C1QBP Pathway Commons Protein-Protein Interactions 1.0 null abnormal mitochondrial ATP synthesis coupled electron transport MGI Mouse Phenotype Associations 2023 1.0 null precentral gyrus, right, bank of the precentral sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.862609 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GATA1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0444 BRD-K38615104_-666_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HOXC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06143 HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31141 H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null decitabine_homo sapiens_gpl570_gse30985 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K59369769_HY-10161_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59864 GSE144443_0_v_6_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null alphatubulin GeneRIF Biological Term Annotations 1.0 null PPARG JASPAR Predicted Transcription Factor Targets 1.0 null TAF1 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30432 Perturb_7946_KO_MED12_SRP201365 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.53153 RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75873 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9810535-41590_2022_1370_MOESM3_ESM.xlsx-Table_S3-MECOM_up_genes_MECOM Rummagene Transcription Factor Associations 2026 1.0 null SNU449_LIVER CCLE Cell Line Proteomics 1.0 3.11649 superficial stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77902 PTPN1_KD_GSE54157_673_human_KM-H2 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null EVI5L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.59448 mitochondrial membrane GO Cellular Component Annotations 2015 1.0 null NCI-H513 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -1.86628 GSE203158_0_v_8_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RPL23A Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CCDC141 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00573848 GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881906 Perturb_7599_KO_CTNNB1_ERP109990 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.29816 ZNF326 Pathway Commons Protein-Protein Interactions 1.0 null CTCFL ENCODE Transcription Factor Targets 1.0 null IALM_LUNG CCLE Cell Line Proteomics 1.0 3.87947 BRD-K69543414 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16872 H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null DV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.21669 GSE180200,GSE180201_2_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K64329997 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21893 H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null D-336MG Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.02168 GTEX-XPVG-1826-SM-4B64X GTEx Tissue Sample Gene Expression Profiles 1.0 0.877884 H3K36me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null skin HPA Tissue Protein Expression Profiles -1.0 -1.19224 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.881486 RELA_GM18526_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMK1-1326-SM-4B65Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.00494 BRD-K95822658 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35507 BRD-K40117723 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67633 KAT2B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL3G-0008-SM-4E3JX GTEx Tissue Sample Gene Expression Profiles 1.0 0.989466 HT1376 CCLE Cell Line Gene CNV Profiles -1.0 -1.79763 GTEX-POYW-0006-SM-2XCF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.924068 BRD-K89638177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05916 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K21025364_NVP-TAE226_HT29_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ribonucleoprotein complex biogenesis GO Biological Process Annotations 2023 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.20363 FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.993639 POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NME1 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POP4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-R55E-1026-SM-2TC5S GTEx Tissue Sample Gene Expression Profiles 1.0 1.18912 ZNF143 ENCODE Transcription Factor Targets 1.0 null KP-1N Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.51906 PES1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1443 MAGED1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00733853 PMC11985509-41467_2025_58704_MOESM7_ESM.xlsx-ZNF385A_vs_NLS-Unnamed_1_ZNF385A Rummagene Transcription Factor Associations 2026 1.0 null H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K64483847 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07468 lymphocytic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.447576 adrenal gland GTEx Tissue Gene Expression Profiles 1.0 0.848291 BRD-K40318276 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51351 GTEX-TSE9-0008-SM-4DXT8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.868773 HMGN3 ENCODE Transcription Factor Targets 1.0 null GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42973 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64456 CTCF_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PLZ6-1626-SM-3NB23 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05346 BRD-K43896262 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16328 them GeneRIF Biological Term Annotations 1.0 null CCAR1 Pathway Commons Protein-Protein Interactions 1.0 null DDX5 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K45928581 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38356 NONO Pathway Commons Protein-Protein Interactions 1.0 null OVISE CCLE Cell Line Gene CNV Profiles 1.0 1.91043 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AIMP2 Pathway Commons Protein-Protein Interactions 1.0 null Inferior colliculus, dorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72715 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37847 NOC4L Pathway Commons Protein-Protein Interactions 1.0 null GSE93309_2_v_0_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null embryoday6.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.64372 GTEX-XUW1-0008-SM-4BOQH GTEx Tissue Sample Gene Expression Profiles 1.0 1.35196 ZBTB33 ENCODE Transcription Factor Targets 1.0 null GTEX-XGQ4-0008-SM-4AT3Z GTEx Tissue Sample Gene Expression Profiles 1.0 2.58925 Superior colliculus, motor related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08062 Lung squamous cell carcinoma_LUSC_TCGA-18-3412-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.07847 BRD-K41876347 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58063 GTEX-O5YV-0326-SM-2I5H2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.952064 GTEX-R53T-2026-SM-3GIJF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22807 U2SURP Pathway Commons Protein-Protein Interactions 1.0 null abnormal heart left ventricle size MGI Mouse Phenotype Associations 2023 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19627 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Epstein-Barr Virus_Akata BL clone-4hr starve_None_GSE19761 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.99607 NB4 CCLE Cell Line Gene CNV Profiles -1.0 -1.72483 SYK_druginhibition_288_GSE43510 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -3.90992 Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14067 CTCF_GM13977_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A19500257_geldanamycin_HEPG2_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null VEGFR1 Kinase Library Tyrosine Kinome Atlas 1.0 95.83 RPP30 Pathway Commons Protein-Protein Interactions 1.0 null Cranial nerve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.08 lung BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.959473 TO175T CCLE Cell Line Gene Expression Profiles -1.0 -1.5836 H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null STAT5A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8647_KO_GATA4_SRP287180 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.7696 BRD-K44432556_VU0418946-2_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null FOSL2_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.880247 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A39996500_radicicol_LNCAP_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K81181894 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34437 Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 16636670-Table2 GeneSigDB Published Gene Signatures 1.0 null Perturb_3276_KD_RORA_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Mitochondrial myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.408 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.891807 Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TDRD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37223 nucleus of the central acoustic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37662 RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Renal Insufficiency CTD Gene-Disease Associations 1.0 1.25463 H3K36me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null SHSY5Y CCLE Cell Line Gene Expression Profiles -1.0 -1.51375 GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09973 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null theobromine-2995 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null septohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03769 GTEX-W5X1-2326-SM-3GIL6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.847924 EW8 CCLE Cell Line Gene Expression Profiles 1.0 2.28808 noretynodrel-7471 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K56188606 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.05737 macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null NELFA Pathway Commons Protein-Protein Interactions 1.0 null BRD-A89354030 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03745 Lung adenocarcinoma_LUAD_TCGA-38-4632-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-0006-SM-2XCFE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.66946 GSE240027,GSE240030_5_v_3_atrx_mouse RummaGEO Gene Perturbation Signatures 1.0 null CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K99650219 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00343 tubocurarine chloride-6351 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCOR-22465074-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16678 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01848 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.958431 fulvestrant-1146 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TET1-21451524-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BronchialEpithelialCells BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.873352 GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03349 BRD-K34640380 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.97825 BRD-K79090631_CGP-60474_HEPG2_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K98343273 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43492 GTEX-S7SF-0006-SM-3K2B6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64232 BRD-K53354260 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12481 DLX5_KO_GSE22381_5_mouse_ear (otic vesicle) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-SNMC-1526-SM-2XCFN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35965 EZH2-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ETS1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASPH Pathway Commons Protein-Protein Interactions 1.0 null mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38506 HNRNPUL2 Pathway Commons Protein-Protein Interactions 1.0 null COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.966977 BRD-K29028138 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53333 GCIY COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19634 Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAUZ-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QMR6-0011-R7A-SM-32PKL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02989 VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.893 EP300 ENCODE Transcription Factor Targets 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K32511780 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.99422 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.33572 THUMPD1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTF2E1 Pathway Commons Protein-Protein Interactions 1.0 null RPS14 Pathway Commons Protein-Protein Interactions 1.0 null ventral tuberomammillary nucleus, superficial part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24491 BRD-K29806938 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02624 CTBP1 MSigDB Cancer Gene Co-expression Modules 1.0 null cervical cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.132841 PMC12289921-41467_2025_62099_MOESM5_ESM.xlsx-MI-2-80-Gene_Symbol_MITF Rummagene Transcription Factor Associations 2026 1.0 null PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.87145 GTEX-TKQ2-1026-SM-33HB7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16208 GTEX-SE5C-0008-SM-4B64J GTEx Tissue Sample Gene Expression Profiles 1.0 1.74225 GTEX-PSDG-0008-SM-48TE5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1925 PTBP1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1993 GDSC Cell Line Gene Expression Profiles 1.0 1.61214 GTEX-POYW-0726-SM-2XCEO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824944 gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044086 Perturb_6446_OE|KD_EGFR|TRIM24_SRP100743 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 translation GO Biological Process Annotations 2015 1.0 null CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MARS Pathway Commons Protein-Protein Interactions 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null French Canadian Leigh disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.298 ASCC3 Pathway Commons Protein-Protein Interactions 1.0 null RXRB Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.989274 BRD-K62236460 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.66264 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERBB2_knockdown_234_GSE8373 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.89664 BRD-K31122616 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6655 GTF2B Pathway Commons Protein-Protein Interactions 1.0 null MS (Multiple Sclerosis)_B Cell Lymphocyte_GSE10064 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.4094 Perturb_376_OE_PRC1/NLS3A_SRP223097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.77919 SF3A1 Pathway Commons Protein-Protein Interactions 1.0 null SMYD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31483 MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24598 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.926676 TAF1_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BT549_BREAST CCLE Cell Line Proteomics 1.0 2.72717 GATA4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00528901 HNF4A Pathway Commons Protein-Protein Interactions 1.0 null BRD-K59658487 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09474 reticular formation of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14502 mantle zone of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91999 PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF Rummagene Transcription Factor Associations 2026 1.0 null MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.632963 Perturb_13969_KD_Elavl2/Elavl3/Elavl4_ERP133202 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.00174 CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WDR73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15972 Perturb_4141_KO_Apoe_SRP131850 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -14.5883 769P_KIDNEY CCLE Cell Line Proteomics 1.0 2.24865 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.45096 BRD-K10135449 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.01921 BRD-K47754225 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2652 GTEX-Q2AI-0826-SM-48TZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.06563 Perturb_8369_KO_Mlxipl_SRP148418 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.61551 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K29850806 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45042 Perturb_15373_KD_BRCA1_SRP294453 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 PRKCI Pathway Commons Protein-Protein Interactions 1.0 null MCM3 Pathway Commons Protein-Protein Interactions 1.0 null COLGALT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11973 H3K14ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.956349 PMC5848610-supp_gr.228809.117_Supplemental_Table_S3.xlsx-Table_S3F-Supplemental_Table_S3F_ZFX_binding_pattern_clustering_information_for_genes_with_promoters_bound_by_ZFX_related_to_Figure_2I_ZFX Rummagene Transcription Factor Associations 2026 1.0 null RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.989891 HDAC2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12875_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cdx2_20696899_caco2_lof_human_gpl570_gse22572 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.357376 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.966977 PBX1 ChEA Transcription Factor Targets 1.0 null GUF1 Pathway Commons Protein-Protein Interactions 1.0 null GSE139239_1_v_5_ddr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.980165 BRD-K36807301 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.97746 KDELR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06059 CTCF_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01480 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.25216 GSE140092_0_v_1_socs3_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNU869 CCLE Cell Line Gene CNV Profiles -1.0 -1.39808 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K03214579 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12695 smooth muscle HPA Tissue Protein Expression Profiles -1.0 -1.44783 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.868994 BRD-K31883990 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22911 CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K97534490_-666_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948994 BRD-K06226868 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13004 H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null C19orf53 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -2.26915 POLR2AphosphoS5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2190_KD_ETS2_SRP083762 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.40253 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06418 Perturb_15688_KO_Rel_SRP075924 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.71618 GSE98964_1_v_4_tet2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PWOO-1226-SM-48TCO GTEx Tissue Sample Gene Expression Profiles 1.0 0.989982 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TM4SF18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89356 intracellular organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.879921 BRD-K32000549 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00421 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PW2O-1926-SM-2S1OB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30214 lateral part of MM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08932 ZBTB7A ENCODE Transcription Factor Targets 1.0 null nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.436026 GTEX-Q734-0426-SM-48TZX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846558 Perturb_374_KD_DHX16_SRP309315 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.3979 BRD-K15739647 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51621 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null cellular protein metabolic process GO Biological Process Annotations 2015 1.0 null GCIY CCLE Cell Line Gene CNV Profiles 1.0 1.61616 FLI1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT1 ChEA Transcription Factor Targets 1.0 null BRD-K96575636 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08258 ESCO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00895 BRD-K12994359_Valdecoxib_PC3_24.0_h_177.6_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.916692 20081105-ST-2 GeneSigDB Published Gene Signatures 1.0 null GTEX-PWO3-0011-R2A-SM-2S1OX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19986 BRD-K77908580_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SUPM2 CCLE Cell Line Gene Expression Profiles -1.0 -2.27591 BRD-K68705041 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83165 mantle zone of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18931 BRD-K69097969_VU0418939-2_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BCOR LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00802923 Schwalie et al.Nature.P1_Adipose tissue_Mouse CellMarker Gene-Cell Type Associations 1.0 null GTEX-RU1J-0008-SM-46MV9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26463 SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.03074 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.929682 Perturb_12341_KD_METTL18_SRP235648 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Acute Myeloid Leukemia_LAML_TCGA-AB-2956-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SUCLG2 Pathway Commons Protein-Protein Interactions 1.0 null CDC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42103 19225562-TableS1 GeneSigDB Published Gene Signatures 1.0 null ZNF354C JASPAR Predicted Transcription Factor Targets 1.0 null ESF1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_4526_KO_Chaf1b_ERP006640 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.2477 Mitochondrial encephalomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.409 MAX_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.04452 SETDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62603 harman-2150 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ABAT LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00493007 CUX1-19635798-MULTIPLE-CANCER-TYPES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28482 SPATS2L Pathway Commons Protein-Protein Interactions 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.88622 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null MALME 3M BioGPS Cell Line Gene Expression Profiles -1.0 -1.01734 SBC-5 GDSC Cell Line Gene Expression Profiles 1.0 1.65566 H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RPS6 Pathway Commons Protein-Protein Interactions 1.0 null SRSF5 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K46322281 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3141 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24082 16207381-Table1Sa GeneSigDB Published Gene Signatures 1.0 null RKO Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.22802 GSE104022_1_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null BRD-K60337438 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62729 Atherosclerosis_Aorta Smooth Muscle Tissue_GSE420 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.51378 epirizole-1845 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K23614490 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13717 BRD-K29415052_NVP-BGT226_HT29_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null FOXP2_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null bonemarrow_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.04789 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37847 SULT2A1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00473 MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.7628 PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Nafamostat DeepCoverMOA Drug Mechanisms of Action 1.0 0.29 RRP12 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WCDI-0002-SM-3P61U GTEx Tissue Sample Gene Expression Profiles 1.0 0.881286 GABPA ENCODE Transcription Factor Targets 1.0 null nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.15027 CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null VARS2 Pathway Commons Protein-Protein Interactions 1.0 null CCR5 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00634713 GTEX-T6MN-0426-SM-32PMF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.969476 LSM6 Pathway Commons Protein-Protein Interactions 1.0 null PMC10025425-mmc3.xlsx-ADNP_WH-gene_ADNP Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WQUQ-1426-SM-3MJFD GTEx Tissue Sample Gene Expression Profiles 1.0 1.18217 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20121 RIF1 Hub Proteins Protein-Protein Interactions 1.0 null BCL3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZH-1626-SM-3DB74 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.900494 ovary_8a HPA Tissue Sample Gene Expression Profiles -1.0 -1.17997 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.91963 NFIC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CMK86 CCLE Cell Line Gene Expression Profiles 1.0 1.58613 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1500_BREAST CCLE Cell Line Proteomics 1.0 3.49156 MYC-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null medial part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08027 PMC12188705-msphere.00110-25-s0007.pdf-100-THAP7_THAP7 Rummagene Transcription Factor Associations 2026 1.0 null FANCI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0543 ATF2 ENCODE Transcription Factor Targets 1.0 null CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K42191735_buparlisib_BT20_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SRRT Pathway Commons Protein-Protein Interactions 1.0 null CEBPB-24764292-MC3T3-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PF-00875133-00-5923 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K37657772 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.03646 TARS2 Pathway Commons Protein-Protein Interactions 1.0 null RBMX Pathway Commons Protein-Protein Interactions 1.0 null ESYT2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7987_KO_Id1_SRP147556 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.03422 heliotrine-6035 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SP1 ENCODE Transcription Factor Targets 1.0 null CTCF_astrocyte of the cerebellum_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.939105 BRD-K44432556_VU0418946-2_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GMPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63596 deep layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.976674 DDX17 Pathway Commons Protein-Protein Interactions 1.0 null RPS9 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38499 STAU1 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.866348 MTCH2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00509769 GTEX-X62O-0826-SM-46MW8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.949214 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE93309_5_v_0_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03104 GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64609 PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-Unnamed_1_MSC Rummagene Transcription Factor Associations 2026 1.0 null LXF289 CCLE Cell Line Gene CNV Profiles 1.0 1.54315 GEMIN5 Pathway Commons Protein-Protein Interactions 1.0 null NRF1 ENCODE Transcription Factor Targets 1.0 null Perturb_1344_KD_ARID1A_SRP336358 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.2459 SPSB1 Hub Proteins Protein-Protein Interactions 1.0 null Perturb_7933_KD_Spt6_SRP132004 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.16405 ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.913247 Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hyperplasia CTD Gene-Disease Associations 1.0 1.47322 Lung squamous cell carcinoma_LUSC_TCGA-60-2719-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.989125 GABPA_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K41306114 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15547 BRD-K36575696 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.87958 CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERA-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K22854578 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65299 ALYREF Pathway Commons Protein-Protein Interactions 1.0 null BRD-K72615639_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GATA2-22383799-G1ME-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC4147934-1755-8794-7-50-S3.xlsx-gene-set_table-MYC_New_MYC Rummagene Transcription Factor Associations 2026 1.0 null PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Unnamed_1_MYC Rummagene Transcription Factor Associations 2026 1.0 null CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3545-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 H3K79me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NRF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-0008-SM-47JWO GTEx Tissue Sample Gene Expression Profiles 1.0 1.06666 GTEX-XUYS-0002-SM-47JXL GTEx Tissue Sample Gene Expression Profiles 1.0 1.08927 CTCF_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF461 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22579 imatinib_homo sapiens_gpl96_gds3045 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K02708799_GSK-1059615_HCC515_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null serotonin-3311 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.73638 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.853482 Lung squamous cell carcinoma_LUSC_TCGA-66-2767-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVKATE Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.60723 CREM ChEA Transcription Factor Targets 1.0 null Perturb_7543_KD_HSF1_SRP275505 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BJ-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Weight Loss CTD Gene-Disease Associations 1.0 1.18326 intracellular part GO Cellular Component Annotations 2015 1.0 null r4 part of descending trigeminal sensory nucleus, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96768 postsynaptic ribosome SynGO Synaptic Gene Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB33_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A79768653_sirolimus_BT20_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.45122 r3 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0352 ZBTB33_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K87909389_S1230_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null sulindac-1857 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A27056524 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55284 Type II spiral ganglion neuron_Brain_Mouse CellMarker Gene-Cell Type Associations 1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837887 CTCF_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.28456 organelle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045145 NIHOVCAR3 CCLE Cell Line Gene CNV Profiles 1.0 2.10583 GTEX-V955-2026-SM-3GAFA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.928893 CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.48703 CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K34542210 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31985 BRD-K38538662 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05236 ott1_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.051155 CTCF_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -3.13541 GTEX-S32W-2426-SM-2XCAT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.870771 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.54943 H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K81473043_-666_HT29_24.0_h_0.35_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K98088240 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01997 Perturb_14491_KO_Caprin2_SRP236878 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.52237 BRD-K71216961 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35296 PRDM1 JASPAR Predicted Transcription Factor Targets 1.0 null BRD-K09511124 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40172 Perturb_13889_KD_BRCA1_SRP135799 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.95812 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K42191735_buparlisib_MCF7_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SOX2-22085726-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16471 GSE63048_11_v_6_morc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null gemfibrozil-2113 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-WFG7-0001-SM-3P61S GTEx Tissue Sample Gene Expression Profiles 1.0 1.72083 BRD-K09635314_-666_CL34_6.0_h_80.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null FASTKD2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_1066_KO_Esr1_SRP087718 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.90944 PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-7_names_TP53 Rummagene Transcription Factor Associations 2026 1.0 null 15897907-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null POLR2AphosphoS5_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF1_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K58985886 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34276 GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34575 ChIP_NANOG_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K87340219 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67119 POLR2A_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64122 GTEX-Q2AI-0526-SM-2I3EJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.860972 TP63_01_327 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.58504 Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.966977 BRD-K74710236_-666_MCF7_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTF2B ENCODE Transcription Factor Targets 1.0 null BRD-K42732309 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.61095 GSE149075_6_v_4_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2021_Mut_Ikzf3_SRP308042 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Perturb_17720_KO_Apoe/Ahcy_SRP342341 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.07759 primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.0942 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NFYA ENCODE Transcription Factor Targets 1.0 null mantle zone of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36355 Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.926898 GSE70499_5_v_2_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null promoters GeneRIF Biological Term Annotations 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5K2-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K27229533 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34917 POLR2A_GM10847_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL15 Pathway Commons Protein-Protein Interactions 1.0 null POLR2AphosphoS5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K01754917 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24346 Perturb_13442_KD_Taf12_SRP119047 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.95161 ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K38904629 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27833 superficial stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45356 MYC-19079543-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null organic substance biosynthetic process GO Biological Process Annotations 2015 1.0 null superficial stratum of r5Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16944 SLC7A11 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00658804 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.49758 NFYB ENCODE Transcription Factor Targets 1.0 null POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05408 DKC1 Pathway Commons Protein-Protein Interactions 1.0 null macromolecular complex GO Cellular Component Annotations 2015 1.0 null H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null Perturb_17383_Mut_Zc3h12a_SRP328189 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.48369 BRD-K88573743_A443654_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Anterior cingulate area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19043 cytochrome-c oxidase deficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.468 KLE COSMIC Cell Line Gene CNV Profiles 1.0 2.36889 TIA1 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.997635 Perturb_8916_KO_KDM1A2a_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.6163 Craniofacial Abnormalities CTD Gene-Disease Associations 1.0 1.0766 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K36795325 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59267 USF2 ENCODE Transcription Factor Targets 1.0 null mitochondrial ribosome GO Cellular Component Annotations 2015 1.0 null HuO9 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.75933 Perturb_10035_KD_PUM1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.78307 integument TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-K32251128 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.84425 H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CEBPZ_02_05 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60578 28S ribosomal subunit, mitochondrial CORUM Protein Complexes 1.0 null CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null increased mitochondrial DNA content MGI Mouse Phenotype Associations 2023 1.0 null sapiens GeneRIF Biological Term Annotations 1.0 null Lateral reticular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15317 BRD-K20969558 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.74487 ESYT1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K40175214_-666_HA1E_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K04010869_PROSTAGLANDIN A1_HT115_6.0_h_1.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_13709_KD_RNF2_SRP351230 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 SKIV2L2 Pathway Commons Protein-Protein Interactions 1.0 null COV318 CCLE Cell Line Gene CNV Profiles -1.0 -2.78415 amygdalohippocampal transition zone, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.867563 MAX_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K79635719 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3953 RAD21_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K42918627_GSK-2126458_PC3_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H4K91ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mitochondrial ribosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Perturb_4291_KO_Farp1_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_3933_KO_TFAP2A_SRP273704 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC1359 CCLE Cell Line Gene CNV Profiles -1.0 -1.43547 EMG1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K23427500 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15853 primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06516 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.64874 BRD-K46458719 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57807 TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.83106 BRCA1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE201042_6_v_10_ptpmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HDAC1 ENCODE Transcription Factor Targets 1.0 null DDX27 Pathway Commons Protein-Protein Interactions 1.0 null H3K79me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTF2I Pathway Commons Protein-Protein Interactions 1.0 null SNRPB2 Pathway Commons Protein-Protein Interactions 1.0 null EIF2S3 Pathway Commons Protein-Protein Interactions 1.0 null BRD-A51777634_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null mitochondrial gene expression GO Biological Process Annotations 2023 1.0 null GATA1 ENCODE Transcription Factor Targets 1.0 null NOP9 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K01805176 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.74475 LYL1-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29873 posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.96366 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22601 H3K79me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intracellular non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 TEAD4 ENCODE Transcription Factor Targets 1.0 null MYC-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14727_KO_YTHDF2_SRP285790 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.7855 BRD-K10027041 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.76984 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null iodixanol-3023 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null cochlear nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2689 H3K18ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IQGAP1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96586 SMARCC1 Pathway Commons Protein-Protein Interactions 1.0 null MZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39184 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-1909 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVN-1626-SM-48TZC GTEx Tissue Sample Gene Expression Profiles 1.0 1.50548 NRBP1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00540164 8505C COSMIC Cell Line Gene Mutation Profiles 1.0 null caco2 HPA Cell Line Gene Expression Profiles 1.0 1.21538 hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3914 Autosomal dominant nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.621 POLR2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.877326 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00024 GSE185944_0_v_1_pth1r_mouse RummaGEO Gene Perturbation Signatures -1.0 null KAT2B ENCODE Transcription Factor Targets 1.0 null GSE112860_3_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCT-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null TMIGD1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00485113 intermediate stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04348 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84648 BRD-K49721311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01885 ccaat GeneRIF Biological Term Annotations 1.0 null CD3EAP Pathway Commons Protein-Protein Interactions 1.0 null BRD-K28512751 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22863 POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null BRD-K93788137_PF-431396_HEPG2_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A50913845 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16762 Perturb_11736_OE_KLF5_SRP091857 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.4685 PML_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.53523 SAOS2 BioGPS Cell Line Gene Expression Profiles -1.0 -0.863823 protein1 GeneRIF Biological Term Annotations 1.0 null membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04391 H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K73051782 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0328 FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null LSM1 Pathway Commons Protein-Protein Interactions 1.0 null CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 15735024-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6424_KD_LOC646329_SRP220725 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.04378 BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-W5WG-0002-SM-3NMDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.72401 hsa-miR-124-3p MiRTarBase microRNA Targets 1.0 null Perturb_5230_KO_Kmt5b/Kmt5c_SRP194976 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE178255_3_v_0_tlr4_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-A73150064 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22448 STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER ChEA Transcription Factor Targets 2022 1.0 null GTEX-OHPN-0011-R1A-SM-2I5GB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860966 CCT7 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null interstitial nucleus of Cajal, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.857279 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.54607 PRPF31 Pathway Commons Protein-Protein Interactions 1.0 null LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_205_KD_Robo1/Id1/ld3_SRP193147 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.82319 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF1_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE190186,GSE190188_8_v_10_apoe_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE120595_0_v_1_arid2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PRDM14-21183938-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CEBPD ENCODE Transcription Factor Targets 1.0 null PSMD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45586 Perturb_1785_KO_Atf4_SRP201328 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.0721 FOSL2 ENCODE Transcription Factor Targets 1.0 null GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40286 CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Cervical Neoplasms CTD Gene-Disease Associations 1.0 1.34983 BRD-K08233096 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.97438 mantle zone of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25362 BRD-K53647853 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27958 GSE171724_4_v_6_ezh2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865367 GSE112763,GSE112767_4_v_1_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.877026 CTCF ENCODE Transcription Factor Targets 1.0 null BRD-K77119472 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1241 hsa-miR-4436b-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 MRPS18B Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7728_KO_MED12_SRP201365 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.91055 16728581-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZU-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02828 Multiple Myeloma CTD Gene-Disease Associations 1.0 1.20328 SRP9 Pathway Commons Protein-Protein Interactions 1.0 null MYC_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K07164317 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3648 H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lymphoblastic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.513743 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.221025 organelle LOCATE Curated Protein Localization Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Superior colliculus, motor related, intermediate gray layer, sublayer a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73752 SR GDSC Cell Line Gene Expression Profiles -1.0 -2.75765 GSE160083,GSE160084_1_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null BRD-K64469421 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.01414 15374877-Table2 GeneSigDB Published Gene Signatures 1.0 null BRD-K95763144 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31764 BRD-K02625776 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6266 H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LUZP1-20508642-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BRD-K64890080_BI-2536_SKBR3_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ARID1A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00462865 RPS3 Pathway Commons Protein-Protein Interactions 1.0 null SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34193 PHF20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04545 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28227 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K52136059 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0162 BRD-K32471649 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.74023 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42729 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K83209781 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19295 OVSAHO CCLE Cell Line Gene Expression Profiles 1.0 1.38447 HS819T CCLE Cell Line Gene Expression Profiles -1.0 -1.934 CTCF_GM12869_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.04983 Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.33711 scale TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.283899 POLR2A_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.30785 USP10 Pathway Commons Protein-Protein Interactions 1.0 null NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08166 BRD-K50053371 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24826 CTCF_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4808_KO_Mapk1_ERP004375 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.78596 RAD21_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K53703060 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.98466 Optic atrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.04 GSE225656_2_v_1_tsc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78936 GTEX-QEG4-0006-SM-2I5FY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.840907 BRD-K80945184 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23958 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-64-5778-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU1076 CCLE Cell Line Gene Expression Profiles -1.0 -2.04191 PMC10944252__F2 PFOCR Pathway Figure Associations 2024 1.0 null BRD-K86158100 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50436 Perturb_5901_KD_CUX1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.22327 GTEX-XQ3S-0526-SM-4BOQA GTEx Tissue Sample Gene Expression Profiles 1.0 0.953932 H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BCLAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K66254772_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K15025317_Bay 11-7821_SKM1_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K87385385 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44096 GTEX-RWSA-0926-SM-47JXW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1841 BRD-K17753765 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37033 WHSC1 ENCODE Transcription Factor Targets 1.0 null MYC_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Spinal nucleus of the trigeminal, oral part, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9177 CTCF_GM10266_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null troglitazone-1070 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PANC1 CCLE Cell Line Gene CNV Profiles 1.0 2.0159 FAM98A Pathway Commons Protein-Protein Interactions 1.0 null BRD-U51024685_HG-6-64-01_HME1_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ATG2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05782 GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13025 NARS2 Pathway Commons Protein-Protein Interactions 1.0 null Sarcoma_SARC_TCGA-JV-A5VF-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RTCA Pathway Commons Protein-Protein Interactions 1.0 null BRD-K83946740 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09723 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CREB1 ChEA Transcription Factor Targets 1.0 null BRD-A18328003_GDC-0980_MCF10A_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null imatinib_homo sapiens_gpl96_gds3042 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X62O-1626-SM-46MW9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13165 NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02131 17616640-TableS1 GeneSigDB Published Gene Signatures 1.0 null EST1-17652178-JURKAT-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_16456_KO_CHUK_SRP229998 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 E2F1-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K19220233_JNK-9L_LNCAP_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K97421379 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.86554 PTRF Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.3607 GABPA_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7894_KD_TEX10_SRP321656 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 AFF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15837 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K54925224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39336 CREB1-15753290-HEK293T-human ChEA Transcription Factor Binding Site Profiles 1.0 null MYBL2 ENCODE Transcription Factor Targets 1.0 null Perturb_1407_KO_Pth1r_SRP341470 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE148692,GSE148695_7_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null MSH2 Pathway Commons Protein-Protein Interactions 1.0 null MAFK_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QEG5-1426-SM-447AS GTEx Tissue Sample Gene Expression Profiles 1.0 1.02514 H3K56ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null pancreas_6b HPA Tissue Sample Gene Expression Profiles -1.0 -0.851867 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.983968 Perturb_10029_KD_CELF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.37558 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4530 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GSE93309_2_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TFB2M Pathway Commons Protein-Protein Interactions 1.0 null SPC25 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00544623 BRD-K61934967 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12763 GTEX-X585-2426-SM-46MW2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04325 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8693_KO_METTL1_SRP314965 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Triangular nucleus of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09969 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8867_KD_PNN_SRP063860 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GSE255432_4_v_0_imeglimin_mouse RummaGEO Drug Perturbation Signatures 1.0 null PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GRSF1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_2078_OE_PUM2_SRP072710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NR2F2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.71301 BRD-K68939871 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07263 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.53705 CPSF7 Pathway Commons Protein-Protein Interactions 1.0 null CEBPB_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVN-1326-SM-48TZ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20737 KPNB1 Pathway Commons Protein-Protein Interactions 1.0 null DPY-21335234-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null OGT LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00851435 HSPA9 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_4860_KD_BAF47_SRP188516 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.67344 HCC1897 CCLE Cell Line Gene CNV Profiles -1.0 -1.52596 PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null EBF1 ENCODE Transcription Factor Targets 1.0 null cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.38025 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NFATC1 ENCODE Transcription Factor Targets 1.0 null Perturb_16457_KO_CHUK_SRP229998 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 TCF12_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LSM2 Pathway Commons Protein-Protein Interactions 1.0 null EIF4A1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K08489825 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04403 GSE62843,GSE64371_4_v_0_furan_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WFJO-1026-SM-3GIKL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.946357 Perturb_3381_KO_Ptpn2_SRP159185 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.08514 PATU8988S CCLE Cell Line Gene CNV Profiles 1.0 1.86335 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.36559 CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.84271 GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63471 POLR2AphosphoS5_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null sirolimus_homo sapiens_gpl96_gds2494 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GSE200673,GSE200691_2_v_3_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2 Rummagene Transcription Factor Associations 2026 1.0 null anteroventral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02277 MZ in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.855366 GATA1_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K40329609_NCGC00184830-01_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SNRPD2 Pathway Commons Protein-Protein Interactions 1.0 null MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05823 GTEX-OIZG-0008-SM-4E3J2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.915779 BRD-K05804044_AZ-628_HT29_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_352_OE_JUNB_SRP287831 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GSE188870,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null BRD-K38342865 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53709 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K81795824_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null FAM241B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34038 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6ES-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null METTL1 Pathway Commons Protein-Protein Interactions 1.0 null small heart MGI Mouse Phenotype Associations 2023 1.0 null GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.966627 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06567 PMC8384902-mmc2.xlsx-3_ASCL1_high_subtype-Gene_Symbol_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K55891520 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22788 NRF2-20460467-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null ranolazine_mus musculus_gpl1261_gse25767 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.34039 NCC021 COSMIC Cell Line Gene Mutation Profiles 1.0 null subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17459 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRKCDBP Pathway Commons Protein-Protein Interactions 1.0 null BRD-K29707171 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48634 Superior colliculus, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.88268 BRD-A45498368_WYE-125132_MCF7_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 ribosome GO Cellular Component Annotations 2023 1.0 null IMPDH2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_15667_KD_Srsf7_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.84278 SNUC2A_LARGE_INTESTINE CCLE Cell Line Proteomics 1.0 6.54951 BRD-K61053165 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3159