association dataset threshold value standardized value SF539 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1258 Nucleus of the lateral lemniscus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59138 MZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.844937 COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.906363 NECTIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50243 hsa-miR-3150b-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Posterior parietal association areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3418 SW620 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE220600_1_v_2_clpp_mouse RummaGEO Gene Perturbation Signatures -1.0 null NHLH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53444 Lung adenocarcinoma_LUAD_TCGA-91-6836-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01748 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04273 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.92163 ChIP_SETDB1_19884257 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.45724 MFF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99543 ALG10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44918 H3K9me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70029 PCGF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90308 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.858037 BET1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68098 r1 part of intermediate nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25865 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Aortic valve stenosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.16 NLRP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97114 Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19781 brownfat BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 MAP2K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08408 H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1 ChEA Transcription Factor Targets 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null UBE2E3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80705 POLR2A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.18935 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0148 TOB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11769 inner CP in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19351 periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24873 CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.658915 ZNF749 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50837 layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32746 LTF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91972 PCNA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43415 A498 CCLE Cell Line Gene CNV Profiles -1.0 -1.54763 RAB6C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3418 AKT1_OE_GDS2308_508_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CCDC120 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76423 AOB, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52689 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.519 SNU216 CCLE Cell Line Gene CNV Profiles 1.0 1.41938 SPI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LDLR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43612 Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87268 SPI1 ENCODE Transcription Factor Targets 1.0 null superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48601 NUDT22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26785 POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LATS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05902 cortex of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32933 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03916 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MO-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral tuberomammillary nucleus, superficial part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66428 NCIH2073 CCLE Cell Line Gene CNV Profiles -1.0 -2.28984 Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0435 MYC_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.51834 USP2_KO_GSE43517_20_mouse_kidney GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null POLR2A_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null DNTTIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18676 GSE214931_4_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null Metabolite levels (X-11787) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.783038 LEPROTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99473 NCI-H82 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.8588 UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZDHHC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62019 KLK8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83768 MSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07834 ETV7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7622 ANKRD24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75204 GSE144919,GSE145177_1_v_0_dazl_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07889 ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.6012 SFT2D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83546 WM1799 CCLE Cell Line Gene CNV Profiles 1.0 2.06296 ANKRD39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58987 CCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21692 LS DepMap CRISPR Gene Dependency 1.0 7.01085 SOCS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00165 LS123 DepMap CRISPR Gene Dependency 1.0 2.79587 EDRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84817 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.990736 BCL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11524 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86818 NFATC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42591 GNB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00386 MSANTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17405 Congenital heart disease (maternal effect) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.639794 RNASE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37727 TMEM147 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32698 TMEM205 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98597 PTAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5048 PCI6A DepMap CRISPR Gene Dependency 1.0 9.98591 POU4F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.38693 USP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94783 DUSP23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51607 r8 portion of ambiguous motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2801 SLC16A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4902 TDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66024 BARHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3984 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46159 USO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13832 AARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08429 ANKRD65 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97034 superficial stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.0423 MAX::MYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2381 SEC24D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74631 LAMC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21161 ZDHHC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62961 inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42771 CCDC142 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54606 dentate (lateral) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.883661 Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCNN1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63805 ATP1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02544 PIWIL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29146 SF295 CCLE Cell Line Gene CNV Profiles -1.0 -1.66186 SH3GLB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69872 Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4303 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PF-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACAD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69093 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-O2-A52N-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LAMTOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82828 L-540 COSMIC Cell Line Gene Mutation Profiles 1.0 null COA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04559 TSN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96735 Ventral part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41249 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884255 p3 portion of the substantia nigra pars reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.70863 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.8588 SPPL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21376 VMCUB1 CCLE Cell Line Gene CNV Profiles 1.0 1.95018 KLHL25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42296 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32596 SJSA1 CCLE Cell Line Gene CNV Profiles 1.0 1.48237 SLC39A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07305 HIF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74489 anterior pretectal nucleus, ventral superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24917 NDUFS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37688 NRF1 ENCODE Transcription Factor Targets 1.0 null ENTPD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99149 DLX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7856 POU2F3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24261 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03934 NUDT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58209 ZNF615 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03883 Lung squamous cell carcinoma_LUSC_TCGA-60-2703-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null ADD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3249 MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06107 DNAJB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60007 MYCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25429 CBARP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84944 CCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52076 SLC66A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33752 LAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77164 WDTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52389 OE21 CCLE Cell Line Gene CNV Profiles -1.0 -1.44321 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884255 GTPase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.039 HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.68478 YIPF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9156 superficial stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24876 TBX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89185 UPCISCC026 DepMap CRISPR Gene Dependency 1.0 3.90663 r1 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4209 PHLDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41594 ZNF652-21678463-ZR75-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null C6orf132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84766 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TENM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.724 IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18222 Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66712 CXorf38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52222 SMC1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24677 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884255 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB361 DepMap CRISPR Gene Dependency 1.0 2.13559 DDX39A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.5781 EMX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31218 SNX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43547 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18334 HOXD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25644 CDK2AP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83059 Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77296 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null ARGFX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76912 RCBTB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33828 Central linear nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17925 ERAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47215 MAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8956 ZNF384_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AXIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.39929 HSPA14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06774 superficial stratum of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3298 CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00007 red nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19641 Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66934 FZD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77944 BCL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77914 RRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13684 E2F6 ENCODE Transcription Factor Targets 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16467 AKT1_OE_GDS2308_499_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null IL18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21692 Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r1 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08027 GLI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42927 KLF5_KO_GDS3509_553_mouse_ES cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null KMT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96041 ZNF542P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73681 NADK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07369 ANKRD49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84696 DMRTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33114 NKX6-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02165 REV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68429 CENPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17561 ERVV-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69601 superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51066 medial septal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11725 SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZNF770 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52011 GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Sarcoma_SARC_TCGA-DX-AB2Z-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.92279 H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null LRP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07486 TLE5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99414 YMB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.65412 GNL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86045 Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 68.3926 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null pyramidal layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34218 ZNF584 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42517 Anteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43202 TP53-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null PAIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69747 VKORC1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24792 SRA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12231 RGS11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21761 superficial stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66428 outer SZ in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38834 Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.6036 TXNDC17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01372 Lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17251 USP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51671 Lung squamous cell carcinoma_LUSC_TCGA-46-3765-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF212 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75776 BOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83226 CDK8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56723 C11orf96 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22447 superficial stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08567 HMGN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08615 SETDB1-19884257-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PRR36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80395 parasubthalamic nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21639 KCTD15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38638 r4 part of descending trigeminal sensory nucleus, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02887 SVBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72303 Visual areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44595 SAMD4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59913 ERVK3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50502 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FBXL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03132 CCDC47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54189 OVTOKO COSMIC Cell Line Gene Mutation Profiles 1.0 null CMC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07435 outer CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21141 T-24 COSMIC Cell Line Gene Mutation Profiles 1.0 null HUS1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90663 callosal sling Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08037 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1895 GSE236437_0_v_3_aldosterone_human RummaGEO Drug Perturbation Signatures 1.0 null Nucleus of the lateral lemniscus, horizontal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08567 NCIH650 CCLE Cell Line Gene CNV Profiles 1.0 1.47814 AFMID CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33076 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KRBA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24491 H3K9me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.48189 m2 part of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33167 VRK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68677 PLEKHO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92628 TMUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98075 SOX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26238 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TM6SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22415 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9636 GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer 2 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87819 Lung squamous cell carcinoma_LUSC_TCGA-43-A56V-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CYB5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57733 MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100533_TCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 14.4906 HSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86488 PGGT1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23757 CDH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53441 YY1 ENCODE Transcription Factor Targets 1.0 null OS9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06578 SDHC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91076 RAB3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89972 EFNB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45684 Superior colliculus, motor related, intermediate white layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03573 Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.2754 LEFTY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61054 C1orf56 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67029 NDUFB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47722 RBM15B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19351 TFDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43336 TLE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33306 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37596 USP42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16099 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.99531 layer 3 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83785 PROKR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72705 GPR37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40885 NANOG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.10087 NRF1 JASPAR Predicted Transcription Factor Targets 1.0 null JPH4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40401 OPTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47038 POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIRT1_KO_GDS3666_295_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZCCHC17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6668 OCUBM DepMap CRISPR Gene Dependency 1.0 3.24203 H2AFZ ENCODE Transcription Factor Targets 1.0 null MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4951 PANC0813 CCLE Cell Line Gene CNV Profiles 1.0 1.52008 HCFC1 ENCODE Transcription Factor Targets 1.0 null DNAJC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51474 CD20-like family InterPro Predicted Protein Domain Annotations 1.0 null NPFF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91819 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.969452 ELF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GLDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74597 dorsal preisthmic part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01971 LDB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27646 Lateral reticular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0592 superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09347 r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47767 layer 5 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35443 H2BC15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07314 YEATS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36007 ERLIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90523 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.00631 PCGF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99894 ATMIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79261 RPS9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23608 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null TMA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74786 Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1655 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05427 COLO 794 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08607 GRPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51217 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01795 FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0681 Primary visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.12306 ERVV-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59751 SMIM26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26325 hsa-miR-557 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 ROBO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13972 HNRNPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41982 ASIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0026 ZNF581 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80177 Perturb_14493_KO_Cnot4_SRP285155 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.79832 Perturb_860_KO_Tsga8_SRP254760 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 19.301 Side of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.963 PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.4186 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51107 CEP95 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78202 ZNF416 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7188 DCP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93483 superficial stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2882 anterior olfactory area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22323 Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null p2 portion of the substantia nigra pars reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.15114 MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.98417 STARD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71429 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63314 Basomedial amygdalar nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54967 mantle zone of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02101 Posterior parietal association areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10129 lateral mammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61787 MACIR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.32669 Heterotrimeric G-protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.06 Koelliker-Fuse subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20695 superficial stratum of p3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03806 PGM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84771 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8838 TE4 CCLE Cell Line Gene CNV Profiles 1.0 1.35453 UQCRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13407 r8 part of lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65528 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40074 Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89848 Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.43674 snoutepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.07989 stratum pyramidale of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02309 UACC812 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.892163 PDSS2_KO_GDS3454_120_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5532 MYO18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34277 PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-314-FOXP4_FOXP4 Rummagene Transcription Factor Associations 2026 1.0 null FGF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09394 H3K9me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YPEL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89388 ZNF839 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6601 RRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10328 Posterior parietal association areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46681 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68847 OGFOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.14849 INPP5E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06443 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.91354 ChIP_KLF4_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SCC4 CCLE Cell Line Gene CNV Profiles 1.0 2.09549 ANXA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52293 GPANK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34049 GID4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47758 EHF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.5143 SNX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0911 rostromedial tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00986 NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.8192 Accessory olfactory bulb, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18979 PPM1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36129 TAF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.906363 C17orf97 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33212 MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2573 COX6B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26079 KLHDC7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73043 TAF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nrf-1 MotifMap Predicted Transcription Factor Targets 1.0 null SALL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85981 MZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02974 Reflex, Abnormal CTD Gene-Disease Associations 1.0 1.45484 IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2149 WFDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54207 A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.50547 Anteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.04173 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.4099 paralemniscal isthmic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0228 KLF4 ChEA Transcription Factor Targets 1.0 null UBR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78125 JHH5 CCLE Cell Line Gene CNV Profiles 1.0 2.25057 ZR751 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.645578 ISYNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53232 SLC30A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10886 STX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71861 posteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00387 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.46666 PPP1R26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30015 H3K9me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mantle zone of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.219 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.94243 substantia nigra reticulata, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15564 r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09347 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABCB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94365 ATXN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94863 ESD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83845 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.843554 ARMCX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59088 mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48601 GNRH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79704 LPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36642 C19orf25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05957 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2368 posterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.938108 ZFAND2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.36448 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.77991 inner CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09211 superficial stratum of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61617 OSR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13754 Retrosplenial area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08172 NAP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25334 NRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null V-79 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.478 EFNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03461 SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0113 CMTM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39448 ATP2A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5378 MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7861 ECE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66715 SPIRE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38714 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null RHOXF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31705 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16467 outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39011 ventral part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.598 SKMEL30 DepMap CRISPR Gene Dependency 1.0 6.20778 PIWIL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84481 anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48726 ZIC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12611 ANKRD28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31679 RCOR1-19997604-NEURONS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null DGCR8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56365 CTPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37441 OVOL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3389 GAPDHS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46245 SPI1_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2726 pontine nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53227 ELF1 ENCODE Transcription Factor Targets 1.0 null PEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43654 PHF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82433 periventricular stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43374 DHRS7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24291 SEPTIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9302 HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37596 ATG16L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66705 IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.925668 GMCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82242 CSTB_KO_GSE47516_678_mouse_mouse cerebellum at P30 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null superficial stratum of r2BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98082 ILF3_02_148 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.61891 ZR751 CCLE Cell Line Gene CNV Profiles -1.0 -1.63049 ZNF394 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49514 DHX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93615 CSTB_KO_GDS5090_199_mouse_Cerebellum GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SKOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93502 AMOT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68714 Interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.227 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63833 solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.909024 SPI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.5472 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.969452 RPIA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93882 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.34853 VAPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32708 H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MFE296 DepMap CRISPR Gene Dependency 1.0 3.63773 r8 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13194 SPG7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49518 SMC4-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null internal granular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34172 CHD1 ENCODE Transcription Factor Targets 1.0 null BCL7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17247 SPI1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TUSC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9587 EW1 DepMap CRISPR Gene Dependency 1.0 7.85307 LOXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6972 DPH7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44535 CEMIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81972 dorsal part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02004 hsa-miR-4733-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 EZH2 ENCODE Transcription Factor Targets 1.0 null MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ADAMTS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61723 Cytoplasmic side of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.048 IRF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADGRL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84902 Midbrain raphe nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05857 BCAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39934 ZNF525 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39707 Lung adenocarcinoma_LUAD_TCGA-49-6743-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8305-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TANGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00308 HPRT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07963 NAA16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73448 FBXO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20345 KRT19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41478 G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.94243 ZNF432 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61925 DOT1L_DELETION_GDS4295_428_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 7 days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7228 Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.78383 MIA PACA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956258 NPIPB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60409 NR2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3721 GTPBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79085 ZBTB46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24836 MAPK8IP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07778 TP53-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null E2F1 JASPAR Predicted Transcription Factor Targets 1.0 null RUVBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48033 HNRNPA1L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23944 HHEX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27972 inner CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16286 TOR3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45469 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.81773 lateral part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17892 ZNF776 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71584 CPD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6794 PSME4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3486 Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29868 CLSTN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41164 SORBS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01087 SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2173 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.26465 NUDCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17696 temporal muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1674 LATS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4429 BT474 CCLE Cell Line Gene CNV Profiles 1.0 1.71877 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null DPCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88457 MED15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7141 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884255 r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24695 SLC35A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23597 PEG10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40482 USP20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89891 MRPL45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95001 HCC1419 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 SLC35F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6209 SETDB1 ChEA Transcription Factor Targets 1.0 null ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GALNT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85786 RARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41922 anterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04784 COX6B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92905 PABPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.424 PCYT1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25427 ERICH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13721 SRI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41522 CAMA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.98491 PNMA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37753 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1839 USH1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34581 NPAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21727 layer 4 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50186 IRF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0915 PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT Rummagene Transcription Factor Associations 2026 1.0 null MYO1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57953 DHX35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67497 inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.986137 PAX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64186 ENTPD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72628 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.4151 ZC3H7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4411 H9 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.1504 SCH DepMap CRISPR Gene Dependency 1.0 3.36909 integral component of membrane GO Cellular Component Annotations 2015 1.0 null EGR1 ChEA Transcription Factor Targets 1.0 null SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1103 KLHDC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.32471 ACTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88016 KMT5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50246 ANKRD13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59421 TCF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42684 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q7-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DYRK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15694 Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65304 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32936 KU812 CCLE Cell Line Gene CNV Profiles 1.0 1.33055 NINJ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87562 CJM CCLE Cell Line Gene CNV Profiles 1.0 1.42328 KDM5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16353 organelle LOCATE Predicted Protein Localization Annotations 1.0 null A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.92795 CBY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97427 KG1 CCLE Cell Line Gene CNV Profiles 1.0 1.51677 USP44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92254 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23041 ZFP42-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14021 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.444 KMS34 DepMap CRISPR Gene Dependency 1.0 2.41323 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03857 Geniculate group, ventral thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56873 SPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26462 SLC5A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68375 MKKS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25097 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03857 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95734 DGCR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.321 IVD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30347 SCC15 CCLE Cell Line Gene CNV Profiles -1.0 -1.54843 SLC29A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38643 mantle zone of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59468 SEZ6L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28474 EFO-21 COSMIC Cell Line Gene Mutation Profiles 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8808 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SELENOK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71166 ZNF107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27108 WHAMM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77615 Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null GLS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28081 ARHGAP39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2901 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69359 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14913 SAV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1199 COLO678 CCLE Cell Line Gene CNV Profiles -1.0 -2.24383 ZNF124 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75582 HCC1482 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5765 SOX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94505 LDHD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57969 Anterior cingulate area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00159 GSE247764_5_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Retrosplenial area, lateral agranular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23551 r2 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98082 mammarygland.lact. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 CCDC106 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85516 RAB6D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27261 outer SZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18778 SELENOH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33247 ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.239 VASN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33459 SNU-61 COSMIC Cell Line Gene Mutation Profiles 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.39708 MITF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11217 FAM234A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8363 PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02534 Paragigantocellular reticular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02167 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0069 PTPRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04314 outer SZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28204 GPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45414 C22orf23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73006 CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31064 TKT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54736 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.860268 SLC25A34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84461 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66559 SNRPB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13258 H2BC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08968 NCIH727 CCLE Cell Line Gene CNV Profiles 1.0 1.75478 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.906363 URGCP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5021 PHF8 ENCODE Transcription Factor Targets 1.0 null USP49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24793 no abnormal phenotype detected MGI Mouse Phenotype Associations 2023 1.0 null HECA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26637 TRMT10C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57922 lateral periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01748 POLR2A ENCODE Transcription Factor Targets 1.0 null 496100619_HIP_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 10.3381 MESD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75089 C8orf82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36968 MAP3K11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94336 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35853 KLF4-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null ZXDB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51905 ZNF683 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13062 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAPK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4306 hsa-miR-4756-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.602 SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33804 EOGT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44711 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFATC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03076 cerebellar vermis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26222 r2 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08645 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ZNF772 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67023 MRPL35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88123 RFX7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3423 TMEM59L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54809 TCL1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26253 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21891 PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75725 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-genes_with_only_SALL4_peaks-Protein-coding_genes_that_show_only_CUT_RUN_peaks_with_2_SALL4_antibodies_and_no_other_antibodies_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null IGR1 CCLE Cell Line Gene CNV Profiles -1.0 -1.59629 KDM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19603 Presubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0352 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRMT10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72682 REEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88365 RET CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61594 peripheral portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.826717 ZNF143 ENCODE Transcription Factor Targets 1.0 null NCI-H1693 COSMIC Cell Line Gene Mutation Profiles 1.0 null GMPPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74294 Sarcoma_SARC_TCGA-QC-A7B5-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SGSM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59247 Anterolateral visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44091 MAGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64712 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25969 Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07188 ECHDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1269 GDF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34077 superficial stratum of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2801 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBX3 ENCODE Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.0967 TMEM126A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91048 LAGE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66501 RDES CCLE Cell Line Gene CNV Profiles 1.0 1.46072 ZNF345 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83371 ZBTB5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48334 PHLDA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59752 ZNF106 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89678 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.8588 superficial stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64507 SLC38A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31017 MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NDUFA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91832 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.38588 MTX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5489 TSKU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03604 USP6NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31602 MAGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67604 ARHGAP33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54712 ZBTB49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58739 DNMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12201 ZNF701 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83503 FEZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73834 FBF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41942 IGF2R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73669 CRK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.05471 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.06336 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13834 SLC6A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.53292 ZNF41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99376 ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.12985 ELF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11084 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0413 KLHL17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57104 496100419_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.49869 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B6-01A-21R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8585-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPUSD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10643 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.84557 SREBF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8847 superficial stratum of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52428 VANGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15859 TBC1D10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08071 superficial stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50777 PHF20L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40485 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05561 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.4937 NCI-H1770 COSMIC Cell Line Gene Mutation Profiles 1.0 null RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5932 GSE201520_8_v_3_inhba_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25969 ATPSCKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8857 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11361 TMEM139 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0277 HMGN3 ENCODE Transcription Factor Targets 1.0 null Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22853 ISTMEL1 DepMap CRISPR Gene Dependency 1.0 2.49217 PARP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03587 NIBAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21541 IFT22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9545 Intergeniculate leaflet of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49038 ZNF652-21678463-ZR75-1-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3189 METTL16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82243 IM95 DepMap CRISPR Gene Dependency 1.0 2.93638 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null ZNF652 ChEA Transcription Factor Targets 1.0 null ZUP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56553 MCM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38889 Cytoplasmic side of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.053 external part of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32277 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GS-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17326_KO_Dis3_SRP328540 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.7447 GSE88819_1_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null XYLT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18985 GPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80735 Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56829 NGRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85669 BLOC1S6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91553 TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null r9 part of the lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30264 BCL6-25482012-CML-JURL-MK1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GABARAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61522 KLF4-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Sarcoma_SARC_TCGA-SG-A849-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null superficial stratum of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02963 PTGIS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48381 MAP1LC3B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98488 NRF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08676 Lung squamous cell carcinoma_LUSC_TCGA-39-5036-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF500 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88737 SW948 DepMap CRISPR Gene Dependency 1.0 2.80103 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NLRX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41186 Posterior parietal association areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09973 SYN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22533 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.79429 parvocellular part of r8LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6304 CHST13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6506 GSE88819_1_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SHISAL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47973 Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AOB, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36801 H3K27me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SKMEL28 CCLE Cell Line Gene CNV Profiles -1.0 -1.77858 TP53 ChEA Transcription Factor Targets 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21441 colon GTEx Tissue Gene Expression Profiles 1.0 0.865901 POLR2A_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null AKT1_OE_GDS2308_498_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23571 IRF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30023 HOXA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57349 Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21065 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51171 SUM159PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.616294 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0128 SOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.22567 DAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53379 FAM171A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13654 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51799 ZNF69 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62098 ZNF841 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87216 TASK1 COSMIC Cell Line Gene Mutation Profiles 1.0 null THAP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69719 Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.95652 GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.969452 PRKAA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13192 ARL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79443 NUP58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07763 HCE4 DepMap CRISPR Gene Dependency 1.0 11.3361 kidney HPA Tissue Protein Expression Profiles 1.0 0.946134 RPS20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51368 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null AADAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33298 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null SAP30L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9444 rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01 H3C15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49622 NDUFA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03598 TIA1_KO_GSE54418_267_mouse_spinal cord GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5162 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17859 r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13997 POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-507 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 ANKRD27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80227 B3GNT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59135 G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916975 G292CLONEA141B1 DepMap CRISPR Gene Dependency 1.0 2.58791 cell part LOCATE Predicted Protein Localization Annotations 1.0 null GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NEMF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9128 PAPOLB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84448 PAX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86071 TBC1D14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8319 COL1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97412 FOXP2 ChEA Transcription Factor Targets 1.0 null SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31283 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.31219 TSFM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29092 p3 portion of the substantia nigra pars compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45366 FAM50B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66145 mantle zone of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65378 GABARAPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93431 layer 1 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74984 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null LINS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.2986 ZNF365 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67613 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BZ-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LTBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38235 Supratrigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10208 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null FABP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01692 NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.29583 C1GALT1C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24252 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.9297 CDCA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50633 HS936T CCLE Cell Line Gene CNV Profiles -1.0 -1.38749 GSE214931_3_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null FBXO10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61347 Cortical amygdalar area, anterior part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02491 Hemispheric regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.309 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21239 Retrosplenial area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37292 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16944 PBX3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MLLT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.09952 GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of r1Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36202 Entorhinal area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17151 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03126 C1orf122 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68799 EB2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null FOXP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3588 IER5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0834 KCND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49919 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ventral tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2934 CDKN2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61137 ML1 CCLE Cell Line Gene CNV Profiles -1.0 -1.50113 NENF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83874 CCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09899 NPTXR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2339 HDGFL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45667 MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF341 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70018 MICU2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81631 Nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36202 RPRML CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50076 central lateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20609 Dystocia CTD Gene-Disease Associations 1.0 1.01437 C10orf95 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34634 Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.1405 FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0343 GTF2IRD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19887 Perturb_17269_KO_Rfx2_SRP066176 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.87456 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16438 RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Cortical amygdalar area, anterior part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26551 RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.0433 ESET-19884257-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null USP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71062 Retrosplenial area, lateral agranular part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.00853 r1 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36312 MRPS28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39965 NDUFA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26757 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884255 FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4218 MFSD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06264 MARK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26855 superficial stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25773 TM31 CCLE Cell Line Gene CNV Profiles 1.0 1.42893 LRATD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82559 HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PJA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30598 ST3GAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72185 TDGF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65078 G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles 1.0 1.44193 Retrosplenial area, ventral part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29977 ELOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04653 superficial stratum of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01016 Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A2PC-01A-11R-A206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null PRKDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54676 TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4949 ISL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38343 CORL105 CCLE Cell Line Gene CNV Profiles -1.0 -1.70272 Aortic valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 STMN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08196 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03934 AOB, mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40074 SLC4A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03133 HPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7377 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882869 H3K9me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882869 FBH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97218 TUFT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51092 RHOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25274 CSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01652 TE11 CCLE Cell Line Gene CNV Profiles 1.0 1.80257 EPB41L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70584 Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8502 TFAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32401 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.858502 PPM1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89321 ESYT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59523 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYCN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4548 H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ESR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8913 cd8.Tcell BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.858373 Extrinsic component of cytoplasmic side of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.059 outer CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.860577 SETDB1-19884257-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CSTB_KO_GDS5090_200_mouse_Cerebellar granule cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CNOT6L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40383 TMTC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07501 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840737 CEP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61051 MDAMB175VII CCLE Cell Line Gene CNV Profiles -1.0 -1.81323 THAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86423 intermediate stratum of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13164 GR MotifMap Predicted Transcription Factor Targets 1.0 null FOXO3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10733 Lung adenocarcinoma_LUAD_TCGA-55-8507-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 2 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02135 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9759 GADD45GIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35177 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SPAST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85933 CDON CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58217 SP in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.907664 CANX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12012 ZNF382 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18596 AOB, internal plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84142 GSS CCLE Cell Line Gene CNV Profiles 1.0 1.42681 PMC10290283-biol-2022-0622-sm3.pdf-20-NEUROD4_NEUROD4 Rummagene Transcription Factor Associations 2026 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84734 DB DepMap CRISPR Gene Dependency 1.0 3.23624 PIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40797 SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AVL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15831 Entorhinal area, medial part, dorsal zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01675 inner SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03332 GSE147876,GSE147877_4_v_7_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null DDX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.52068 MALME3M CCLE Cell Line Gene CNV Profiles -1.0 -1.69349 H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MARCKSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24177 DNAAF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65061 anterior cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11569 Medial amygdalar nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21469 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884255 FAM86B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43507 LEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35925 rostral ventrolateral reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6465 ARHGEF18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13106 HNRNPUL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99017 SNU182 CCLE Cell Line Gene CNV Profiles 1.0 2.66538 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Major depressive disorder GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 Lateral terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62624 CSTB_KO_GSE47516_18_mouse_brain (P7 cerebellum, P30 cerebellum, cerebellar granule cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null WARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7417 SLITRK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73152 Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19Q-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 48.7215 SHQ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62367 KDM1A_KD_GDS5055_367_mouse_adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-4645-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Retrosplenial area, lateral agranular part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31731 COLO 678 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10543 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29533 PRKRIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9559 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.849312 SPI1 ChEA Transcription Factor Targets 1.0 null LARP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19755 HOXB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4231 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51107 NBPF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75641 EP300 ENCODE Transcription Factor Targets 1.0 null m1 part of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55999 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16804 KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893433 mantle zone of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17991 Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.0831 EP300_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null paraterete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.02432 ZSCAN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92109 IGFBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39662 inner CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.57826 anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07148 p2 portion of the substantia nigra pars compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03884 MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6526 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41P-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4689 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 UCHL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55465 IGR39 CCLE Cell Line Gene CNV Profiles 1.0 1.74941 EN DepMap CRISPR Gene Dependency 1.0 2.38388 TMCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92803 RALGDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.29013 ADAM11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69176 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YX-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40117 EFNA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81989 UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03857 HMGN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05843 SP in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.861804 ARHGEF35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28593 SPI1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SH2D3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25159 CYB561D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1041 KDM5A ENCODE Transcription Factor Targets 1.0 null STAT1-17558387-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47631 ZFP42 ChEA Transcription Factor Targets 1.0 null H2BC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2021 CIART CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7545 ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7368 ACOT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46338 Substantia nigra, reticular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.25996 Nucleus of the lateral olfactory tract, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1843 JcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66637 GNAQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4069 NCIH716 CCLE Cell Line Gene CNV Profiles -1.0 -2.59445 HIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60268 ARMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66715 periventricular stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4134 ZNF468 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24236 ventral posterior parvicellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0161 AFF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51668 GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PIK3R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86333 mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07855 H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null FAM200B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85509 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4959 Anteromedial visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04506 GSE183994_3_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures 1.0 null DCAF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76784 POU4F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62541 HCC1395 CCLE Cell Line Gene CNV Profiles 1.0 1.69023 GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CALR_KO_GDS3680_149_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HPCAL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01646 Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HQ-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRPS9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59963 FARSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34618 HSPA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66477 STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.579 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.35403 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40966 DMAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10289 H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null COX6A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88933 MKNK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98731 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.04975 LANCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17634 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11361 MOAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39451 ARHGEF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59209 MAPK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65973 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21469 A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.71865 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null GSX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20658 TREX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90668 Posterior parietal association areas, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40535 C1orf115 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76829 klf5_18983969_embryonic_stem_cell_lof_mouse_gpl1261_gds3509 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.451857 CHD2_02_196 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.62149 JUN JASPAR Predicted Transcription Factor Targets 1.0 null A1BG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85948 layer 2 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05982 ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24534 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null PRKCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5802 STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null RAC3-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE236454,GSE236456_0_v_1_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures 1.0 null SRP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19564 ICAM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83792 H3C11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14025 PRNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37635 POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZKSCAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20907 FGF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02616 NKX2-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.12046 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1422 ULK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75557 SHP77 CCLE Cell Line Gene CNV Profiles -1.0 -1.94078 p1 part of the substantia nigra reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50925 LPCAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6228 MEIS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70747 MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0888 JAGN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69426 MED27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70863 FLNC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71467 ATAD3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00567 mantle zone of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22395 NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1731 YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null RND2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41517 Lung adenocarcinoma_LUAD_TCGA-78-7162-01A-21R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PWWP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62611 TXNDC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42981 SOHLH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51278 BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884905 MELHO CCLE Cell Line Gene CNV Profiles -1.0 -1.45333 SH2D2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14153 BAG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0622 MCRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05301 Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TSPAN13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56498 TMED9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85557 E2F6_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null m1AD (DM) part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4134 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05561 Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.91158 PKIG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83658 GNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36761 hsa-miR-4673 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 PATU8988T DepMap CRISPR Gene Dependency 1.0 4.63548 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20654 ZNF544 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98491 NUDT17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6917 MAP3K20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34614 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15253 IER3IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24723 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1303 Skin Cutaneous Melanoma_SKCM_TCGA-HR-A5NC-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SARS-BatSRBD_Day4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.85465 WBP1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80491 Subgeniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50478 HES3_KO_GSE64449_186_mouse_Min6 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null lateral tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.11485 TIRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6991 TAF1 ENCODE Transcription Factor Targets 1.0 null RORC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5106 periventricular stratum of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02036 cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17791 Sarcoma_SARC_TCGA-X6-A8C3-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTRH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19992 GOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18984 ADCY3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65374 MED14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73641 intermediate stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88486 NOS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69046 SEMA4D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34241 membrane part GO Cellular Component Annotations 2015 1.0 null AOB, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12116 ZFHX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.7075 posterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09695 TMX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61743 TPRX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42388 HCS2 DepMap CRISPR Gene Dependency 1.0 3.01502 MRPS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73969 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-4784 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 NEK8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93589 Lung squamous cell carcinoma_LUSC_TCGA-56-8629-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12312 PRKRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47547 SLK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72397 496100421_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04817 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null superficial stratum of r1Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41856 ARID4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81512 episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51129 GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25969 FIBIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2134 rostral division of VL Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24828 NCIH2052 CCLE Cell Line Gene CNV Profiles 1.0 1.43983 MRPL47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5837 BRICD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04569 layer 1 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50925 C14orf93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86564 SEL1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29064 ELMOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50092 H3K9me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SGPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22587 TRIM56 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86008 FHL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63592 JUND ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHST6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53428 SIX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91708 TMEM86A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31676 SNU-182 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21441 TBP ENCODE Transcription Factor Targets 1.0 null ENO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5281 POLR2I CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45068 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2708 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05427 midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.941447 TP63 ChEA Transcription Factor Targets 1.0 null GSE150895,GSE150896_0_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null INSM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63333 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.09488 RBMS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10183 ATF7IP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03589 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 WDR35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33564 endoplasmic reticulum LOCATE Predicted Protein Localization Annotations 1.0 null USP2_KO_GDS5079_25_mouse_kidney GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RBM11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09329 RDH14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41426 DIPK1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9295 VPS37C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33419 Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53777 Lung adenocarcinoma_LUAD_TCGA-86-8359-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRPL39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3057 EMX2_Deficiency_GDS3173_607_mouse_Embryonic urogenital epithelium - day 10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.40863 SP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11883 G-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null Posterior parietal association areas, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10051 OCIAML3 DepMap CRISPR Gene Dependency 1.0 2.60265 HDDC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84623 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.16297 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25969 BTG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80699 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Field CA2, stratum oriens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18076 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3235 TRIM22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82309 Familial hypertrophic cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.712 Purkinje cell layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62172 MRPS11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76848 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.969452 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AGTPBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69208 PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1 Rummagene Transcription Factor Associations 2026 1.0 null AOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04487 RFX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76958 superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.26345 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.947664 TWIST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.28853 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.951 APOL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4137 periventricular stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66786 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.939577 UBB_KO_GDS3906_492_mouse_Testis - 14 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MRFAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94586 SPATA5L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.569 p1 portion of the paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.04391 MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.955201 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.94243 GSE145249_1_v_3_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42813 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.889091 Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.7929 ZNF160 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13897 127399 DepMap CRISPR Gene Dependency 1.0 2.75036 CLPTM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30391 SPG11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73123 BEX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01618 FEM1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21144 TDOTT DepMap CRISPR Gene Dependency 1.0 2.71164 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.04121 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Posterior parietal association areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11571 H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RSBN1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47025 IPC-298 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68847 KYAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96098 TRMT12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37372 MINPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15663 CSTB_KO_GDS5090_398_mouse_cerebella GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TTC38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46131 RETREG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51505 H3K27me3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PARK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94406 CLUH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9172 TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4054 isthmic portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60437 Substantia nigra, compact part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.127 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE191105_2_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ARHGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22357 CPNE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.786 FAM20B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84517 GNAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65414 KP1N DepMap CRISPR Gene Dependency 1.0 3.37714 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AD-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TUNAR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52221 PLEKHF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.94414 PNO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11234 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.05408 IFIH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31526 TRAPPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17918 CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PGRMC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65435 NDUFAF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52454 TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0721 Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.9754 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NT5DC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7047 OST4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42239 CCDC74A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67881 NUDT12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68156 LBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36953 MLEC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60826 SATB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18576 ADD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18706 DISP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52616 SUM1315MO2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.574506 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Crop TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.575 PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null WDR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19139 MFE280 DepMap CRISPR Gene Dependency 1.0 3.59521 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.47246 DDX49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57867 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.34964 Retrosplenial area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21812 PTPN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56533 Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39585 CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ABL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3512 NACC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56753 Primary visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64694 CD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.946 tongueepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.958817 KLC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85579 endopiriform nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31314 LGI4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4731 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GS-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRAK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12919 TRIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17568 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51799 POLR2AphosphoS5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null occipital cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65729 Primary visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70679 Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53878 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.25996 PEX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.33031 SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.870438 TMEM88 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76724 UBTF ENCODE Transcription Factor Targets 1.0 null JHH-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24983 Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DENND1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48968 ST6GAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38403 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 L2HGDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43993 AMOTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01355 VENTX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32188 ICC137 DepMap CRISPR Gene Dependency 1.0 4.11037 ZNF197 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22453 HSP90AA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55715 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.873616 Retrosplenial area, lateral agranular part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17488 PCDH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01604 superficial stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52754 HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TENM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21929 IQGAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53631 Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRR19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75418 EIF2AK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.17494 ODR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64267 ETS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08153 H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CDKN1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76932 FAM124A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67868 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.3429 DUSP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08819 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.901358 AP5Z1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85994 IPC298 CCLE Cell Line Gene CNV Profiles -1.0 -1.33819 Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 part of cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.219 OTUD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14525 Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29912 TE5 CCLE Cell Line Gene CNV Profiles 1.0 2.86726 PSMG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.27804 HLA-C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97213 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63112 PITX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81416 Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OG-06A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF677 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46827 HDGFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30705 Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.72017 PLPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73913 NR3C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94227 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null R3HDM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46643 GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MRPL24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92579 PRMT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94588 RPRD1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72365 Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19746 DYNC1H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67025 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35553 MARVELD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19434 molecular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29385 membrane LOCATE Predicted Protein Localization Annotations 1.0 null UQCRH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49168 GADD45A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72031 PBX3 ENCODE Transcription Factor Targets 1.0 null TRIM37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38916 KATNBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37009 r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07855 outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16508 ATP5MC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58589 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11443 ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.2184 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 MLMA COSMIC Cell Line Gene Mutation Profiles 1.0 null RINL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00275 MASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77132 KLLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70632 hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1197 ZNF691 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42096 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2778 ABL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22797 ODF2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15979 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.95402 SLC39A14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89245 FOXP2-21765815-NEURO2A-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LTBR_INHIBITION - 1 Day_GDS2005_728_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5935 TRIM28_knockout_301_GSE32224 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.61789 YBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67625 layer 1 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09358 HINFP JASPAR Predicted Transcription Factor Targets 1.0 null CHD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79191 NDUFB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40595 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51107 QTRT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59371 APLN_KO_GDS3228_601_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null zona incerta Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.949355 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.876975 PPIP5K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50307 ALDH1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99777 E2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71752 IRX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32525 PCI15A DepMap CRISPR Gene Dependency 1.0 2.21179 KHDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22058 PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10003 CHTF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76378 Anxiety Disorders CTD Gene-Disease Associations 1.0 1.34694 NAGS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80091 Skeletal Muscle Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.26597 FOXO1_KO_GSE40655_481_mouse_T reg GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null 697 DepMap CRISPR Gene Dependency 1.0 2.71011 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16467 Kdm1a_KD_GDS5055_274_mouse_3T3-L1 preadipocytes - 24h GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null FEZF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91097 LIMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36997 NHLRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46728 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.9729 EBC1 CCLE Cell Line Gene CNV Profiles 1.0 2.02931 p3 portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15106 UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TXNDC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9638 Rectum adenocarcinoma_READ_TCGA-CL-4957-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null liver HPA Tissue Protein Expression Profiles 1.0 1.81209 GSE179031_0_v_2_foxp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null AP3M1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44075 SJSA1 DepMap CRISPR Gene Dependency 1.0 3.59305 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.904084 ZNF208 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6389 inner CP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.983789 FOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3529 KDM5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33294 bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868823 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32252 mantle zone of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58782 TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEP104 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13199 RCCFG2 DepMap CRISPR Gene Dependency 1.0 2.30681 ovary GTEx Tissue Gene Expression Profiles 1.0 0.829328 FAM3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59431 ChIP_ZFP42_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ZNF384 ENCODE Transcription Factor Targets 1.0 null septal organ BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.38663 medial amygdala, anteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00756 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893433 BECKER DepMap CRISPR Gene Dependency 1.0 10.9565 Primary visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29787 JHU011 DepMap CRISPR Gene Dependency 1.0 3.45708 ACAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74478 GSE147876,GSE147877_2_v_7_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null ELF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94497 superficial stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27701 POU3F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50465 layer II of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.939273 DIMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88683 NOTO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27484 stomach BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 NDUFAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7873 PcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52168 PEBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64743 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.991569 H2BC21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77795 YAPC CCLE Cell Line Gene CNV Profiles -1.0 -1.43937 NHLRC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50583 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.969452 KAT14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82403 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.07891 terete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50478 EP300_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1885 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51107 Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.2972 GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4606 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SW1990 DepMap CRISPR Gene Dependency 1.0 2.47315 Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0031 C14orf132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60747 superficial stratum of OCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65554 ELF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7779 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.7621 MYC ENCODE Transcription Factor Targets 1.0 null CD177 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56563 COCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98995 DYNLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30951 TCF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0656 Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44995 SKMEL2 CCLE Cell Line Gene CNV Profiles -1.0 -2.08376 FCSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56702 KLHL31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67319 superficial stratum of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22358 B3GALNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68735 KP3 CCLE Cell Line Gene CNV Profiles 1.0 1.54933 MYO1E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76691 TOX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64595 hsa-miR-545 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Anteromedial visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31439 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21441 IFRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07319 SKN3 DepMap CRISPR Gene Dependency 1.0 12.4233 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03916 H1-3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89789 COLO-680N COSMIC Cell Line Gene Mutation Profiles 1.0 null PDLIM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32466 Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A6SH-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CITED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64327 NFE2L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44945 ZNF808 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05247 H3-5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89653 MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Retrosplenial area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11166 SCNN1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35832 TFEC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5687 Cortical amygdalar area, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15562 SSTR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54769 SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69801