association	dataset	threshold value	standardized value
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93496
PRRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13279
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54404
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3293
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84766
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3333
ARL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05259
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
OSBPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65349
ZBED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26123
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04578
GTEX-NFK9-1226-SM-3LK79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2366
Parietal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.231
BRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37721
RCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20589
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91122
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30993
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
PLAAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.068014
POFUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1091
SLC31A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49736
vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.790827
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982332
GTEX-PLZ5-1826-SM-3NB22	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33249
Crop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.12
MAMDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3081
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891756
GTEX-SIU7-0226-SM-4BRX2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.86147
ZNF674	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80907
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.059
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.037
TARBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57594
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3188
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.969668
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93155
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
SFMBT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6442
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2651
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28178
GTEX-SN8G-0226-SM-4DM6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35548
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12133
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8056
Small_Intestine-neutrophil	Tabula Sapiens Gene-Cell Associations	1.0	-0.0477035
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-X3Y1-0926-SM-3P5YT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01576
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983063
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79108
CCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21692
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5438
RPP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13955
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Lewy neurite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4751
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6344
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9113
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04946
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83371
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Communicating hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
TRAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05318
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.82955
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.774
FANCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67412
Alzheimer's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3699
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3232
ANKRD28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31679
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4148
ATAD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34915
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.935
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.169
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
neurodegenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42512
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32364
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
APOBEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22205
PPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44948
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81719
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62265
GTEX-P4PQ-0526-SM-2HMKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19004
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.646
Body Height	DisGeNET Gene-Phenotype Associations	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
AHR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8502
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923589
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27473
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79168
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43904
POTEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19958
Progressive supranuclear palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	1.15457
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48154
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0568
DDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12967
GTEX-X4LF-0526-SM-3NMB6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03507
CLPTM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30391
Perturb_9854_KD_LUC7L3_ERP124746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.29431
OXTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25502
CFAP418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62099
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906705
ARMCX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22124
AS3MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76768
RPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92319
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84512
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8519
PAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29069
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65597
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2621
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Fibrinogen Assay	DisGeNET Gene-Phenotype Associations	1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4798
TEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70206
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98264
IQGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46925
ZFPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22927
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2012
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43007
fat_e	HPA Tissue Sample Gene Expression Profiles	1.0	1.40299
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANKRD33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99739
SMIM30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71257
bone marrow	HPA Tissue Gene Expression Profiles	1.0	0.98676
SBNO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37814
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04392
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908365
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6477
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T8EM-0626-SM-4DM62	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897972
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0152
POT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10205
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37717
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1007
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
RUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61041
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
MAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17224
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18678
MTRES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07783
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.302
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
Gerstmann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
SIKE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67664
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ADCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63871
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029963
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00861
Glial filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.55
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28713
appendices_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73152
Perturb_13019_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.83529
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937205
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48125
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.325
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06815
BL988 (PDS5A)	NURSA Protein Complexes	1.0	null
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09472
TMEM147	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39426
OGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35072
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00057
lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.128119
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
CRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60389
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12623
PDLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14445
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96918
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
TENM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.724
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34949
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927696
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Perturb_709_Mut_ASXL1_SRP305063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.81139
GTEX-OHPN-0226-SM-48TBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859377
Inferior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZFTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7907
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
bone marrow	HPA Tissue Protein Expression Profiles	1.0	3.0466
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83756
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12479
TRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28008
STUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44342
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BTBD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83057
ZNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98484
HACD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56466
CERS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49463
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
RIOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78931
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75649
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861698
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-XUZC-1126-SM-4BOPZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.64864
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64541
GTEX-XBEW-1426-SM-4AT4J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990417
GTEX-RU72-1026-SM-46MUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64192
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tauopathy	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
impaired eosinophil recruitment	MGI Mouse Phenotype Associations 2023	1.0	null
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9973
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64087
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.526
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71292
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28078
GTEX-SNOS-0726-SM-4DM5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43737
GTEX-QDVN-1126-SM-48TZ7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84438
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22173
TMEM219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64757
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6072
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.446
dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.927932
alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.932484
ZSCAN20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65085
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
TMED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
peripheral vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.790827
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3513
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07081
Amyloid plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.895
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33262
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11713
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AGAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77478
MKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06816
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12377
TSPAN17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65988
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUZC-1526-SM-4BRV4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31495
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1796
RPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97466
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75418
t67-small-intestine_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.78462
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09104
SSBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88456
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68426
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06253
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16776
Normal pressure hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
LKAAEAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.837414
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871463
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14804
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3373
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.002
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15489
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9602
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.877
ATP2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55269
MAFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60559
ZBTB49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58739
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28233
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66904
ELMOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56207
ZNF716	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12536
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
susceptibility	GeneRIF Biological Term Annotations	1.0	null
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28563
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5202
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6702
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
NFYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86468
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32433
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8702
STX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84735
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
MANBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98959
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
enhanced contextual conditioning behavior	IMPC Knockout Mouse Phenotypes	1.0	null
IMPDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84758
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78478
GTEX-WOFM-0126-SM-3MJFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34159
LGALS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47207
BLTP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89614
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7897
SEMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07546
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01137
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.065
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.09616
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13109
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
BRD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59535
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30849
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15997
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2621
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7127
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2621
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45794
Cornu ammonis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
TMEM63A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31952
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9625
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2621
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
ITGB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79068
SDCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11762
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76708
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
H2AC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13823
HOXB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94011
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
DUS4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3475
PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20435
rectum	HPA Tissue Protein Expression Profiles	1.0	0.969668
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58313
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5192
SNAPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43787
GTEX-WOFM-0726-SM-3MJF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1141
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
APLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82214
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05113
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0531
GTEX-V955-1826-SM-4JBIL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56969
Perturb_700_KO_INTS6_SRP299234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.66178
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5951
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.742329
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22901
PEG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40482
cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.237706
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050163
GTEX-WFON-1326-SM-4LVMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59944
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2706
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUP133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35876
esophagus	HPA Tissue Gene Expression Profiles	-1.0	-1.03062
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.429
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97604
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882447
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19221
FOXD4L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53311
FAM78A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6839
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882447
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30664
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.075042
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08697
RTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45676
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8142
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881102
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04813
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
C1orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07171
FZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87516
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61818
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36262
MEIOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14226
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Perturb_9023_KD_NR4A3_SRP324495	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.42508
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4796
TCF7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58384
ZNF106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84613
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96595
Meynert's basal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39992
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1007
KURAMOCHI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.6828
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2317
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
ZNF43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20004
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Bone_Marrow-granulocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.775076
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48651
ms4a6ams4a4e	GeneRIF Biological Term Annotations	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
ALDH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99777
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49937
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30426
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1419
Cerebral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.483
WWC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78146
cluster	GeneRIF Biological Term Annotations	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1914
disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67743
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4492
ZNF548	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24361
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ETAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51151
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4673
BEST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72096
GTEX-UJMC-2026-SM-3GADR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.419
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CCAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4097
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.28043
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Alzheimer's disease 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
MAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63045
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7138
GTEX-S341-1526-SM-4AD6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949355
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19636
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39108
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82319
DNAJC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71075
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2436
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21937
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4307
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56035
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881102
CYCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50858
ZNF429	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04931
NKX6-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76716
PDXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5207
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97497
ZNF621	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24017
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62208
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27317
UBAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89016
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12211
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08308
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06675
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.706
NCOA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68929
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05325
PMC8410861-41467_2021_25544_MOESM32_ESM.xlsx-MCR-MCR_cells_-_DGE_iGCA_testis_vs_adult_testis_from_GSE112013_and_GSE124263_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185519_6_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840138
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862822
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58313
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866347
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23283
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43442
SRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31332
UCMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89114
TIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42744
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8453
ASB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80041
SIGIRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71598
GTEX-V1D1-0326-SM-4JBIY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933139
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36721
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62654
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9338
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1655
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1344
ESRRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00654
MYF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06452
RAB3IL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08385
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2661
GTEX-PLZ5-0726-SM-2I5F9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907744
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32031
FOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13935
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49322
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.967207
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5964
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54911
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01038
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92985
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3048
MOSMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86251
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22806
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.04903
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42862
lung_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
ZNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54858
GTEX-WFJO-1926-SM-3GILA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01364
GSE94849_1_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8608
ADSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78001
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
SERINC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36153
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7922
GTEX-PSDG-0326-SM-48TCP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847145
BL391 (RAD21)	NURSA Protein Complexes	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996145
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
Fat-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	7.14182
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
DCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65705
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09562
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02306
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965004
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE179868,GSE180330_1_v_0_ddx21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Amyloidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
MBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59395
DGKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25489
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92216
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60049
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
CRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12108
Lewy body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
NDUFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58059
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29947
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Insulin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.606
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12874
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81868
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74495
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
DSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60181
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54638
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34793
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18225
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	1.1438
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891756
SLFN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98406
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62201
LYSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
TNFRSF10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8212
KLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16502
CEP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12064
CHST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6506
FNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40688
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5974
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.957
COPS7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43988
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48319
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.191
SS18L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27392
RNASEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70563
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87815
kidney_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.991741
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50495
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29831
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951079
FXYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68972
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02398
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIRC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
alzheimer's disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
GTEX-XUZC-0926-SM-4BOQF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824655
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16371
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32813
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04783
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8157
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05304
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82939
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56515
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5126
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.909
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17144
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4471
DUS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52379
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
LRFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56189
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01646
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49587
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53958
KCTD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94864
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2128
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30928
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86165
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00622
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
TSPAN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40616
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19977
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834021
ING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61736
SEPTIN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37088
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11723
DAAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87991
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43989
GUSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42976
Eye-microglial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0306564
HTATIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8938
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69322
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68372
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66282
TMEM88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76724
IRX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09264
NDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54462
FERMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45007
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
t54-hypothalamus_female_1w	MoTrPAC Rat Endurance Exercise Training	1.0	8.93921
EIF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45553
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1574
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891756
GTEX-XPVG-1526-SM-4B66C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04178
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Nasu-Hakola disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7086
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97883
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
ZNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39023
CTAGE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34157
GTEX-Q2AH-0626-SM-48TZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52012
CCDC71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76428
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
GTEX-R55C-0726-SM-48FCN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93613
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.170175
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-W5WG-2726-SM-4LMIC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857273
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05489
PSME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3486
ZIC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12611
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07619
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25134
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60565
TMEM30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14571
GTEX-WFON-0926-SM-4LVMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08439
IPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82304
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52763
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31378
APP-related cerebral amyloid angiopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
disease	GWASdb SNP-Disease Associations	1.0	0.02682
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95286
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48062
ARHGEF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86122
Bone_Marrow-monocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.765281
GTEX-XPVG-1726-SM-4B65W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925047
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
HMCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19971
ARHGEF10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9888
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00981
GTEX-WYJK-1326-SM-3NB2T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05546
TCEA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37284
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3986
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3454
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11418
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59951
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05932
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35596
Cerebral amyloid angiopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42512
CASKIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69487
GTEX-XAJ8-0926-SM-47JXZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884783
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30406
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9119
KYAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30474
cellular_component	GO Cellular Component Annotations 2015	1.0	null
MBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93107
ACBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21608
stomach	HPA Tissue Protein Expression Profiles	1.0	0.969668
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Prostate-myeloid cell	Tabula Sapiens Gene-Cell Associations	1.0	4.61471
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15538
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83465
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2474
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3428
Traumatic brain injury	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
skein-like inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965004
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF527	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55249
LRATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82559
LRP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90208
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2342
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
GTEX-XPVG-1326-SM-4B65P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977516
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29947
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05065
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94831
EBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02213
PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93614
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8133
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7141
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63529
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70836
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0841
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.842163
CAPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30982
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31854
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MMP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18616
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9236
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00813
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.969668
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
MBNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91583
TMEM106C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00661
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57488
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TXLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67228
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19318
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03008
UBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66564
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75336
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30439
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12656
GIGYF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09578
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11138
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
TLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
CIRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18925
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87832
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1007
RWDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11247
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31692
GTEX-N7MS-0326-SM-4E3K2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3816
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56761
POLR2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14048
DNAJC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37844
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95741
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23116
Corneal fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
TCEAL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23092
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
OTUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20393
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28153
PTCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36076
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835346
CDY2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89653
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
MLXIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70456
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16228
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
YPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10176
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24594
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96023
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9254
tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.930828
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16171
RYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87796
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.936
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7823
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30471
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03947
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1339
FUT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05464
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.96957
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0734
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882447
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
GDF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28767
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75812
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9505
enhanced contextual conditioning behavior	MGI Mouse Phenotype Associations 2023	1.0	null
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35791
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34472
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71296
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37212
ZNF93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7929
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10032
KHNYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66276
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89212
HMGXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70038
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7262
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
Neuronitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
SCARB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12299
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	1.72752
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
IKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23779
CHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4215
GTEX-WFG8-1026-SM-4LVMZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21524
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45212
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
arteriosclerosis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.790827
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66288
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.18581
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3503
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0792
GSE224131_2_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1105
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.156006
Fascia dentata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83021
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98731
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6546
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882447
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
ZSCAN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43576
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
DACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25179
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903617
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66366
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
CREB3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20657
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PKP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85391
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	1.00213
CDC25C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19913
Neurofibrillary tangle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.989
CDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55352
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4058
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.128407
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05111
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56382
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978961
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857939
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17064
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69252
cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.790827
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6612
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38019
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55643
a-HCV10 ()	NURSA Protein Complexes	1.0	null
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74728
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49378
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	1.0842
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
KLF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27464
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62321
GTEX-V955-1226-SM-4JBI9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31951
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8793
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20655
GTEX-X5EB-2426-SM-4E3HX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25005
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14907
brain	GTEx Tissue Gene Expression Profiles	-1.0	-2.04969
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55461
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.162
CDK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07411
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09934
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11783
abnormal macrophage physiology	MGI Mouse Phenotype Associations 2023	1.0	null
TRIM32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50359
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49341
TULP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17944
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36166
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46607
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8286
GTEX-OHPK-0226-SM-3MJH6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08238
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.815
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2663
t54-hypothalamus_female_4w	MoTrPAC Rat Endurance Exercise Training	1.0	4.52034
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73248
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51534
CHEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88257
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	3.13371
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
KIF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09943
BHLHE41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14261
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1751
SLC7A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30726
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung-non-classical monocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.677126
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90931
CCDC74A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67881
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3256
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74017
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56132
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40453
SOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13963
MIGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23778
GTEX-XUJ4-2526-SM-4BOO4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01809
HEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31482
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PEDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65268
MYPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69663
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14804
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47344
AGTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69208
LRRC75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42719
Prostate-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	1.06893
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2553
GTEX-XBEW-1526-SM-4AT4K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19012
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
ASCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66053
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37957
GTEX-XQ8I-2126-SM-4BOOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25644
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.058356
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4412
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73941
GTEX-X638-0226-SM-47JZ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01283
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43202
RAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7047
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77081
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19706
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25274
DLGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43227
LRRC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38214
GFUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30239
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16136
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0452
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97883
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WYJK-1426-SM-3NM8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0454
FAM171A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13654
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68067
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41016
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83122
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47291
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42324
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.33
DNAJC30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59784
GTEX-UJMC-1026-SM-4IHKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01689
brain	HPA Tissue Gene Expression Profiles	-1.0	-1.4337
microphthalmia	MGI Mouse Phenotype Associations 2023	1.0	null
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6632
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84918
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
BNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4093
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76781
MATK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77796
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940134
PIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40797
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
histamine-gated chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.89
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14693
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07807
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7909
FANCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58305
PRKACG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56549
GTEX-WY7C-0926-SM-3NB34	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944411
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60602
gangliosidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.652484
EXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75232
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050213
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13478
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972537
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973279
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.703869
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
CHRNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8056
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866849
TCAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3447
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982332
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3962
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24586
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983063
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-U3ZN-1926-SM-4DXSG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27839
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8345
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14499
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32422
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5736
GTEX-P4QS-0226-SM-3NB1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07073
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993374
ZNF679	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05447
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
AGO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77238
KDM6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73208
Perturb_15182_KD_MAF_SRP105796	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.91761
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46259
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9415
GTEX-X4LF-1726-SM-3NMBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91182
Salivary_Gland-monocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.304916
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52041
LMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64908
Basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
CIDEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73519
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.37639
FASTKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64273
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
RINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90885
SLC39A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42142
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60296
Parahippocampal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7488
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856441
FNDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22615
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PEG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46691
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
OLIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23616
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23411
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5716
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
QSOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39351
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42512
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49921
HRH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13004
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.31752
Kidney-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	0.951386
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33137
AATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51002
GSE125403_7_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2021
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977729
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03715
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82452
EBNA1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64546
GART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49183
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-WFJO-0426-SM-4LVM7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17737
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
RTL8C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83512
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.255
CAPN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25308
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86595
BOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19253
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60589
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882447
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04996
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7977
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00829
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68646
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868438
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09646
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0496
COMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.497321
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17246
RBFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57801
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
t54-hypothalamus_female_2w	MoTrPAC Rat Endurance Exercise Training	1.0	6.98115
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3517
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99003
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5929
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.008098
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.594454
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5696
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34438
GADD45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72031
EAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14492
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882447
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57162
Amnestic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
GTEX-OXRL-0726-SM-3NM9A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832586
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03314
Perturb_12960_KD_YTHDC1_SRP309987	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.7335
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42858
CABLES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9927
decreased interleukin-13 secretion	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883099
SEC14L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19325
abnormal eye morphology	IMPC Knockout Mouse Phenotypes	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2621
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61193
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18505
GTEX-S341-0426-SM-4AD5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9011
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22605
Alzheimer's disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
E2F7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88793
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62178
PLEKHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04946
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78592
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16383
fat_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.27792
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40388
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Subarachnoid space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.694
ASH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98871
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01278
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
STK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92044
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895967
Dendritic lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.301
SCAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18779
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67512
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.888644
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10632
AGTRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09838
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0266
CYYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18977
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49188
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28035
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41553
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08618
MSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17213
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18126
SAP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02174
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60007
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91112
Perturb_9025_KD_NR4A3_SRP324495	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.19356
GTEX-OHPM-0226-SM-3LK61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997351
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1629
HLA-DRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62541
MOGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30721
PMC12659123-12864_2025_12285_MOESM12_ESM.xlsx-Table_S12-Table_S12_Differentially_expressed_genes_after_SPI1_knockdown_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28329
GGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91359
GTEX-OXRL-0226-SM-3NB18	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05233
ISX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81371
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
HSPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3176
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44182
ANKRD49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84696
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRPF38B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62085
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53958
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77795
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36822
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13088
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32226
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70192
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.031281
microphthalmia	IMPC Knockout Mouse Phenotypes	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43383
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92444
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FXYD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09129
Lateral tuberal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45377
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
arteriosclerotic cardiovascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.790827
SEC24A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87207
DDRGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.471
PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_id_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6385
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
NUDT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95203
ZNF517	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43137
GTEX-WFG8-1126-SM-4LVN1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03434
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829085
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32315
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.82392
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.123
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859833
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35978
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9134
IGFBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01027
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1657
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906488
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.211597
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73815
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845823
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.080154
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3259
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
CCNO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0188
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.2726
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41701
Middle temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
GTEX-XUW1-0526-SM-4BOP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13666
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Vascular dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70616
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69398
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0685
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5584
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23343
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33342
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77542
NABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05339
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78556
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SMCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95653
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89424
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.991
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52137
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22657
ZNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6619
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49168
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12118
DAOY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883078
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52893
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26343
GTEX-PLZ5-0826-SM-3P5ZW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28922
TOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11769
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02196
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78526
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37049
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.866
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3249
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06335
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16371
Congenital myasthenic syndrome 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
SFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78699
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18063
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05009
PCDHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17975
PFKFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48455
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14621
NSMCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11426
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.653
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04813
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6009
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.969
GTEX-UJMC-0626-SM-4IHJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1557
Lipoprotein-associated phospholipase A2 activity and mass	GWAS Catalog SNP-Phenotype Associations	1.0	0.637972
DCP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22866
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.57941
PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZNF791	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77529
CDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4569
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.861337
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
VCY1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40782
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.12
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33212
MAP6D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72398
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058213
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	1.0	1.029
UBE2N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33787
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
abca7	GeneRIF Biological Term Annotations	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4257
RAB6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3199
FAM135A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5834
SLC39A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71676
CD164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9396
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03933
ZNF222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36253
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308974
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74508
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63176
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10231
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2453
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0447
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00478
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39178
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4938
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86005
Pick's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3238
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
GALNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59607
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98905
LRRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89738
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
Microglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.839
COX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64307
SEPHS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78893
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2371
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22357
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
NRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01107
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
TTLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03314
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85458
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93004
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.994
KBTBD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60327
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04991
Posterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88645
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZNF131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10552
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2224
GTEX-PLZ6-0926-SM-3P5ZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899258
CYB5D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96507
Lewy body dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.15948
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57844
GTEX-WVLH-0226-SM-3MJG6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911294
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1255
TM2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60294
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19874
ST6GALNAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6251
XPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94129
SYNGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57479
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38815
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4235
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
ARL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79443
KCTD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27519
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28648
INSIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9587
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
tonsil	HPA Tissue Protein Expression Profiles	1.0	0.969668
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24974
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12756
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37241
GTEX-R55D-1226-SM-48FE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43821
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
MAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10201
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840138
H4C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81879
CD20-like family	InterPro Predicted Protein Domain Annotations	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
loci	GeneRIF Biological Term Annotations	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4397
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24679
IGFLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7619
GTEX-OXRP-0226-SM-3NB14	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870406
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE224131_5_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.48
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4336
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.46634
alzheimers	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
tay-sachs disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.879833
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75291
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71039
JMJD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20828
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
CRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19662
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42307
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82255
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3298
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53266
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GOTO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08874
PBK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22751
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4382
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05304
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.96842
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
MRPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30043
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03883
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57565
GTEX-XV7Q-2626-SM-4BRVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15337
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Small_Intestine-mast cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0183185
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.693
ZNF800	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92847
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
Mild cognitive impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.107
NFAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82024
CRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07723
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38742
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12712
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0191
central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14804
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
OGFOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87144
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1026
PPP2R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93935
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05506
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
decreased interleukin-4 secretion	MGI Mouse Phenotype Associations 2023	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
NKX2-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09811
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9649
EIF2AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17494
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.72127
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67922
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36757
NPIPB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81265
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
KLHL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41525
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2761
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15921
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965004
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06572
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50551
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8542
DTX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27607
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71066
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83791
SLC25A34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84461
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8107
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8839
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19553
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983063
Tonsil squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
GTEX-OHPK-0526-SM-2HMJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9907
DLX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88418
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.207
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09719
CRELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49323
TRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17568
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94848
MXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40061
TUFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51092
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QLQ7-1526-SM-2S1QA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850752
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.83439
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71501
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76214
SLC25A32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72709
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1541
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826074
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
DBNDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31585
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8635
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93218
GSE93156_1_v_0_idelalisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12654
PAX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24687
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06435
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47671
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebrospinal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.704
CERS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2097
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9058
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89408
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43463
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0625
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	1.3061
ZNF845	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01404
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
tauopathy	GWASdb SNP-Disease Associations	1.0	1.3061
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99215
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857939
DNAJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73808
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18213
GTEX-XQ8I-1626-SM-4BOOI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56253
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3384
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.113971
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42512
Thymus-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	0.814256
NINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71567
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5932
DBF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52203
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983281
PBXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02043
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907002
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.861
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12086
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15308
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
all	GWASdb SNP-Phenotype Associations	1.0	0.029926
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73532
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57492
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22616
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52857
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4639
GOLGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67032
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.316
GON7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74069
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2641
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937813
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43955
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02369
GTEX-U3ZM-0626-SM-4DXTV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849363
Cortical Lewy body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
PMC12209767-bcd-25-0099_supplementary_table_s2_suppst2.xlsx-C_DEGs_RNA-seq-Supplementary_table_S2C_List_of_differentially_expressed_genes_in_IGHUND_vs_IGH_GCB_MB2_DE_DLBCL_HGBCL-DH-BCL2_-BCL6_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857939
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27188
ZNF414	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14911
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042097
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5068
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10868
Perturb_10136_KO_Mir22_SRP149845	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.65763
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
gangliosidosis gm2	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.779841
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8473
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0538
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983063
SPEGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08787
NKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUW1-2326-SM-4BOO5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1866
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02065
ALKBH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00212
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0519
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36104
RNF167	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47629
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8464
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4607
CMPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10269
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30175
PUS7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8546
Medial temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.588
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8852
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84631
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
NBEAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7913
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68224
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982332
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919131
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
HSPA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32633
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53942
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59642
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1637
C1RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5375
atherosclerosis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.790827
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10236
BL1485 (MLST8)	NURSA Protein Complexes	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28471
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12549
GTF3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45707
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902737
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
gamma-secretase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.805
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.12
OCEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45912
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28437
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867878
COA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55386
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
SLC15A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54836
Bunina body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
496100336_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44104
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67358
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30456
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.964
spleen	HPA Tissue Protein Expression Profiles	1.0	1.91857
Perturb_13011_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.89901
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51352
ANKRD13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35183
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
ZNF30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49132
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36862
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
phospholipid-translocating ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.554
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
FNDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99893
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.148
SREK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66371
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76895
Perturb_750_KD_UHRF1_SRP331230	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.7877
TE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91999
GTEX-WFG7-1726-SM-4LVME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42991
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
NOMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62621
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11552
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87622
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99792
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0273
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45924
Kinesin I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PSME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86704
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12814
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26495
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4466
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36324
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42605
ZNF385C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67873
AKAP8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15527
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50587
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4582
Anterior pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.463
dementia	GWASdb SNP-Disease Associations	1.0	0.459894
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84806
Corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845823
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16518
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9445
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ERCC6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68397
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6733
PIP4K2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35204
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91639
WWC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67985
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5287
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Alzheimer disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.033
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6906
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
membrane part	GO Cellular Component Annotations 2015	1.0	null
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848268
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0538
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39059
ZNF69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62098
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82097
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60212
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16347
PANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36284
sphingolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.32774
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Thymus-dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.285326
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.7055
CHST10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60999
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48473
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07482
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8282
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69695
GTEX-QCQG-1826-SM-2S1P2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17891
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15397
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8972
PLAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0719
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27262
GTEX-XBEC-0326-SM-4AT4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08904
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5729
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0656
H2BC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17102
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
decreased eosinophil cell number	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
NSUN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64496
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6145
H4C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.70545
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21772
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62987
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050213
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61594
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52911
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51833
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05929
Temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19884
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831191
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
ZNF416	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71222
KIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57961
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9488
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16391
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79341
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63114
NIPSNAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22408
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30562
GTEX-WFON-1026-SM-4LVMD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972294
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4158
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FBXO46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40767
abnormal eye morphology	MGI Mouse Phenotype Associations 2023	1.0	null
496100647_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04778
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43572
GTEX-UJMC-0426-SM-4IHJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87651
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91819
GSE185519_6_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94967
GTEX-WFON-2226-SM-3TW8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24621
GFPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44816
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7037
Lipoprotein-associated phospholipase A2 activity and mass	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
K562_Glesatinib(MGCD265)_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172615
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03798
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06045
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40189
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08711
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75425
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07869
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54086
SNX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45506
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17791
Basal telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
ELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15238
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32802
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21075
Cingulate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43747
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52293
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40395
PRR29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57714
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52812
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6387
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20519
NHLRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50583
TUBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7536
dementia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.080593
Neurofibrillary tangle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.185
appendix	HPA Tissue Protein Expression Profiles	1.0	0.969668
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97292
SFXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97555
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5781