association	dataset	threshold value	standardized value
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7124
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2141
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24664
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93552
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5932
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LDLRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59971
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1314
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7849
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87202
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9544
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13624
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8927
UTP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25922
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8631
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8935
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0902
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9102
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6328
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99633
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23976
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15321
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7632
GTEx BloodVessel 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	8.9446
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6784
GSE211286_4_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NUP133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33479
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169155_5_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9583
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60041
GSE214596,GSE214598_1_v_4_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53214
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34739
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2443
GSE175920_0_v_1_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2661
RBBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44245
CDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57379
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9568
SYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44798
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22594
GSE62974_1_v_0_epas1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49092
GSE160246_0_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DDX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4417
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36262
GTEx Heart 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	1.0	3.04868
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0577
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87148
RRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64253
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FABP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29691
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09097
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04828
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07295
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AP3M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12203
GSE196699_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17713
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81803,GSE81912_4_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.35267
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EXOC3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12222
GSE112760,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22677
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21363
TSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27181
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1014
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112762,GSE112767_1_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
CTU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22415
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
NPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35045
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1667
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4452
GSE133213_10_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22947
GSE147056_2_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241701_4_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	190.138
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OGFOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09883
ACBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01891
SEC61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57501
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9413
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0401
PTPN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67983
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2204
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12149
PNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03922
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2699
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04146
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01771
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71654
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5018
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4328
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175920_0_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03549
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SEC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22397
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88206
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5682
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DPY19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56441
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5032
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38929
GSE175920_4_v_3_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FTH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22611
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.773
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5111
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9204
SSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33883
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15578
CLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19227
GSE103372_0_v_3_smad1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39689
THOC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61283
ZNF99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12854
TRAPPC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12221
TCEAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58548
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74787
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1697
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.9446
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11884
GSE133213_4_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7729
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27781
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30286
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95727
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86754
CYTH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25375
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.381
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82899
ACTL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91445
RAB5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13833
STRN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48947
GSE211931_2_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8502
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATP5F1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39554
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3724
GLT8D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08404
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4348
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPACA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16808
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8636
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24695
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175920_0_v_3_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9197
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
WDR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23024
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.761
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00383
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2497
GSE175920_4_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
QSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70651
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7774
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24422
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1396
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41256
RNASE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25342
TMED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33831
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180951_6_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11988
METTL25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38949
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6703
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4297
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0902
GSE239436,GSE239441_0_v_1_keap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1352
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1961
GSE205550,GSE205552_2_v_3_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05179
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.126
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27533
GSE201401_2_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLITRK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76348
GSE208435_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7212
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0852
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4201
SLC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0632
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4631
GSE148510_1_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175920_4_v_1_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00653
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45617
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01828
GTEx Heart 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	3.49386
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.544
RPP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47311
GSE216394_2_v_0_pfkp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02272
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80865
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6422
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9689
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2BC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51152
SCN4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36652
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.19271
SLC66A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33752
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3559
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9905
MED25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83361
GSE151782_4_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2148
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15628
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02463
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17615
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3882
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00708
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92603
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5106
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4095
DNAJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33634
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17067
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90343
TMEM104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04016
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FRA10AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12379
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1316
GSE95685_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
TUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19477
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36551
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2208
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17667
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1706
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EYA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01992
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3671
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12712
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1461
CISD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07841
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.089
POLR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37856
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE85302_0_v_1_kat6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44132
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21915
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1058
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0547
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
MT-ND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32755
GSE193624_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1929
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5864
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8461
CCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02626
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCAPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00736
GSE247862,GSE247863_2_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3207
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7957
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18621
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18468
SLX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39191
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50767
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98893
NGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03488
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9049