association	dataset	threshold value	standardized value
ceforanide-3309	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K36627727_T3205_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EPHA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560321
BRD-K86003836_flubendazole_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
vincristine_homo sapiens_gpl570_gse7556	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K32927008_7021926_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
thiocolchicoside-1726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ATP5F1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00367184
TWIST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00792812
BRD-K06792661_Narciclasine_NCIH508_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K24201553_SB 269970 hydrochloride_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.946
BRD-K71059170_Cefixime_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K68174511_torin-2_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K64935403_E0886_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCLY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537818
BRD-K52163391_NCGC00165208-01_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYO1F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0123752
PARVG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00416905
Bronchial benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
BRD-K57027644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41912
CSNK1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578374
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
NECTIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716002
BRD-K99532291_SPB02303_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99545815_PF-562271_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KU812	DepMap CRISPR Gene Dependency	1.0	2.80037
BRD-K49075727_nintedanib_LNCAP_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UMUC11	DepMap CRISPR Gene Dependency	1.0	2.49477
GABRR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00587056
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5884
RHOH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00591108
calmidazolium-486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BPIFA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00506532
EFHD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582561
BRD-K96393402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14605
COQ2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00625688
BRD-K41895714_AS605240_SKMEL28_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.29688
BRD-K03109492_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568313
TNFSF12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539551
FCRL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503758
BRD-A67788537_Salermide_EFO27_6.0_h_120.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRKRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0108126
TRIM69	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0052724
BRD-A14574269_UB 165 fumarate_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NLN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536233
OR10V1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00678143
SNAI1_OE_GDS4596_344_human_SW480 - Colorectal cancer cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MEI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00581244
BRD-K59587063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00544
TNK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597771
BRD-K94176593_TWS-119_HS578T_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1203
BRD-A19500257_geldanamycin_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A79465854_auranofin_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bucladesine-591	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ACSM2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585493
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K13566078_BMS-345541_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K98548675_Parthenolide_SKMEL28_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TEAD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00687108
BRD-K70511574_sunitinib_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EIF4G1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0078924
mefloquine-5724	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GNAO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00897741
BRD-K43620258_3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide_NCIH2073_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOCS5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00637809
AP5S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56059
BRD-K15716662_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CXCL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00672245
sulfadiazine-5523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K01877528_TL_HRAS26_A673_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RHD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0110713
ADCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0106375
BRD-A60414806_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K19220233_JNK-9L_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BTF3P11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00908402
RELB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00852315
BRD-K54484733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15126
CRHBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00831225
BRD-K13113551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16202
MTOR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0114329
PRKAR1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00577796
CLCN7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00740052
PDSS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607066
diflorasone-4077	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
raloxifene-3480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00777728
CTNS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00759658
BRD-K31624501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04092
CTNNBIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00938732
GAS7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0098753
PDE2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623722
Glial cytoplasmic inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
BRD-K45378289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06408
BRD-K56650430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02188
RAB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46424
resveratrol-622	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0775
ICOS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0105413
trichostatin A-7407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FDPS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00543728
DYRK1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0068203
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2924
levodopa-1972	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSK3A_knockdown_203_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.84578
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
RNASE6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00735171
ENPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00981045
BRD-K26760349_HG-9-91-01_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FCGR3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606554
benzethonium chloride-7207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49371609_528116.cdx_MCF7_24.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K56161792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32402
flufenamic acid-1420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K77987382_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K80786583_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513145
BRD-K24671931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26065
AEBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0105391
BRD-K81995936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09098
IRF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00625039
BRD-K13566078_BMS-345541_LNCAP_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2645
STAT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00376583
BCAR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00758941
BRD-K06750613_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAP4K1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00479191
BRD-K37991163_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TOMM40L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64408
U2904	DepMap CRISPR Gene Dependency	1.0	2.65694
ALOX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00432602
BRD-K71040831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54357
FRMD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00634472
tacrolimus-378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TPH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00754653
TYROBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00694503
BRD-K12502280_TG-101348_MDAMB231_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K70511574_S1485_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC4A1AP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526466
BRD-K27599706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99412
BRD-K68303333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34181
talampicillin-7014	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.284965
LYZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00439475
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	5.56999
BRD-K06593056_-666_HEPG2_6.0_h_20.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K88378636_withaferin-a_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CXCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00828945
BRD-K81418486_vorinostat_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
perhexiline-2410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A39646320_H7270_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A67799922_dibenzyline_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K51898276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41148
SSX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00822769
triflupromazine-1813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K83238251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64485
chlorhexidine-2025	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12787259_CX-5461_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K54042694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01007
BRD-K74148702_curcumin_NCIH1694_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUFU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00949786
KCNV2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716092
BRD-K81592585_DM-55-3 BRD-K81592585_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SOSTDC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630661
Pi Mi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.301
BRD-K68065987_MK-2206_LOVO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATP5PB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00764394
BRD-K42918627_GSK-2126458_LNCAP_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K25081034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54681
BRD-K68336408_Tyrphostin AG 1478_SKLU1_6.0_h_56.78_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K95196255_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68174511_torin-2_BT20_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K84514454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80254
MZB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00989148
KCNN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677709
PMC9377669-tx1c00392_si_002.xlsx-Retinol-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
RORC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00826981
BRD-K49630153_NCGC00183226-01_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92317137_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FBXO11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058129
SLC7A14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00781413
PCGF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661626
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33783
BRD-K81006490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24082
BRD-K48749255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09021
BRD-K21680192_mitoxantrone_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TIPIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00779405
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9462
ITPRIPL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00725929
CD93	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00835799
CXCR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00652177
INSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63333
BRD-K75532464_FTI-276 Trifluoroacetate_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
securinine-2729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K12994359_Valdecoxib_U937_6.0_h_177.6_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.17497
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6019
ion binding	GO Molecular Function Annotations 2015	1.0	null
CR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576558
CLEC2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00808382
BRD-K50149147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29917
BRD-K25504083_C8273_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fendiline-7188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADIPOR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588538
BRD-K76415727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20284
cation binding	GO Molecular Function Annotations 2025	1.0	null
thioridazine-1068	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Teriflunomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A19037878_trichostatin A_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fendiline-3190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00662647
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
BRD-K63606607_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K90977883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03636
BRD-K54066059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17234
TNFRSF1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0047862
HCRTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00859612
KDM3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659814
BRD-K65496998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24201
CDHR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00820744
BRD-K77987382_mebendazole_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K98140933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64975
KYNU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0115456
BRD-K68336408_Tyrphostin AG 1478_NCIH596_6.0_h_56.78_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0108113
BRD-K76401790_JNK-IN-5A_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Mitochondrial intermembrane space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.966
BRD-K89930444_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sulfabenzamide-2159	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K78252315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36378
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1974
BRD-K36740062_GSK-1070916_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41859756_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UNG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0102416
BRD-K64577478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06249
acacetin-2189	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42918627_GSK-2126458_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K21025364_NVP-TAE226_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FKBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61221
JAKMIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0069957
BRD-K72636697_QL-X-138_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K65182930_NVP-AUY922_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K64890080_BI-2536_HT29_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADSS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00914551
BRD-K43620258_3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide_AGS_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nod2_21335489_hek293_lof_human_gpl570_gds4416	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.592411
GAD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513456
YRDC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054179
MAFF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00936623
RAG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.007442
BRD-K11853856_PJ 34 hydrochloride_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K72636697_QL-X-138_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCAMP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00704167
BRD-K81418486_vorinostat_NCIH596_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81528515_HY-10159_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K72414522_AZD-5438_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A19037878_trichostatin A_SKMEL1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76833108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94611
doxorubicin_homo sapiens_gpl570_gse11940	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K12040459_AT7867_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K49865102_PD-0325901_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A80960055_3203_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A98283014_C3930_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04257723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2042
BSN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00709119
terfenadine-6823	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49865102_PD-0325901_BT20_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K55187425_ON-01910_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CYP11B2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00643746
KCNQ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00736949
BRD-U61997977_WZ-4-145_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92317137_-666_THP1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K74109371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14619
BRD-K02708799_GSK-1059615_BT20_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A19037878_trichostatin A_NCIH596_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00762632
azacyclonol-2020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ACTL6A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00966984
PMC8108288-gutjnl-2020-321731supp004.xlsx-LPS_stimulation-gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79090631_CGP-60474_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K60132279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04674
vinpocetine-1557	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K14329163_(S)-(-)-Bay K 8644_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K97399794_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MOG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582857
BRD-K77703574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60145
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
famotidine-2029	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ABCB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00927152
ADCK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518142
BRD-K18036262_L-168,049_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1833
SLITRK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00551262
BRD-K05520923_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UOK101	DepMap CRISPR Gene Dependency	1.0	2.5554
BTNL10P	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00795256
IDI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00867091
BRD-K04853698_LDN-193189_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ITGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43173
BRD-K78062244_STOCK1N-27488_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K78431006_crizotinib_SKBR3_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IFI44	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00659466
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6362
DEF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0120007
HTR2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606766
KIR2DL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00374354
ERO1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552421
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.13292
harmol-1750	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
guanabenz-1961	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A19500257_geldanamycin_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
monastrol-627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VPS37B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714883
RECQL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00995605
BRD-K98676510_N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-5-pyridin-2-ylthiophene-2-sulfonamide_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77876
BRD-K41595302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42466
BRD-K69852452_7241-4207_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ACTA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0132588
SDK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588307
tolnaftate-1919	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K70712582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61451
NRIP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0148422
BRD-K14020943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44867
CACNA1I	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00751124
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9003
BRD-A05680309_MLS-0390982_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K45328741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52652
BRD-K64606589_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZMIZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00820625
ELOF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609471
iproniazid-1442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A62809825_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92317137_-666_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DOK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00451628
TNFRSF25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00791314
captopril-1907	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A22032524_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K13567350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02818
BRD-K85606544_neratinib_BT20_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A76528577_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCNN1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00787487
BRD-K51781482_IKK-3 Inhibitor IX_VCAP_6.0_h_6.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.26788
BRD-K28905117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35464
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4638
BRD-A39996500_radicicol_MCF10A_3_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SLC45A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570219
cobalt chloride-379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K84203638_4-[(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy]-N-(4-methylpyridin-2-yl)butanamide_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CYP2A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00499981
BRD-K02130563_S1030_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K05804044_HY-11004_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42191735_buparlisib_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K14788918_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1595
BRD-K88378636_withaferin-a_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PNCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594311
BRD-K92812209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98762
WAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00917911
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.503665
SNU601	DepMap CRISPR Gene Dependency	1.0	2.54519
MFAP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00819356
fulvestrant-523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC827GR5	DepMap CRISPR Gene Dependency	1.0	2.24099
FLT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00717955
pheniramine-1910	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EPRS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00687366
BRD-K48338059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5151
EXD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00462699
ATP9A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00828758
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3438
BRD-K70854630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31415
SLC24A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.008685
BRD-K24132293_piperlongumine (HPLC)_WSUDLCL2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K43389698_BMS-387032_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K13094524_PFI-1_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51753035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11866
trazodone-7452	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K68202742_trichostatin A_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PCNX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00516413
BRD-K87024524_phenelzine_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98568
BRD-K88573743_A443654_BT20_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K89116076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13617
HCC2157	COSMIC Cell Line Gene CNV Profiles	1.0	2.12703
ACVRL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00615179
BRD-K37618799_MRS 1220_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
methylbenzethonium chloride-3943	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TRIM22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00501371
BRD-K22096725_ALW-II-49-7_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4973
KCNN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00657302
CA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579965
MT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.821
vanoxerine-1625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IGSF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00535556
BRD-A28970875_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94325918_-666_OV7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K28122619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01478
RBM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28695
OSBPL6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00722933
BRD-K83336168_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CBX6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557396
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1467
verteporfin-6817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NALCN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633138
Perisynaptic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
ERBIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00782282
SRMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00595331
RKI-1447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17923
SNX33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616295
BRD-K65494150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73943
BRD-M86331534_BJM-ctd2-9_SNUC4_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSTO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00842743
BRD-K70379342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25442
BRD-A43126523_NCGC00183690-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4276
BRD-K14027855_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
BRD-U60236422_WH-4-025_BT20_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GPX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675706
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.04427
BRD-K52321331_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDHR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00784862
AIM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0133334
BRD-K63068307_ZSTK-474_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450732
CSF2RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00883283
BRD-K18190982_COT-10b_SKMEL1_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K74761218_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00992584
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48353
fluorometholone-6247	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461598
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.2944
BRD-K18978449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09743
wortmannin-911	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K98493452_honokiol_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCND2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00776272
TXNRD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00635743
SETD1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00686182
SMPD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611983
SRSF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00795245
PI4K2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00480482
IRF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0115266
MS4A14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00457286
MRPL19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620147
BRD-A49848186_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70511574_sunitinib_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LYPD6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00872379
OLIG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00837498
VPS26C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00816254
BRD-K25504083_C8273_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SLC22A23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00605108
ASCL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0148577
BRD-K35687265_S1362_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1047
Prestwick-983-6520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
0317956-0000-4334	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GRM7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0121467
BRD-K79090631_CGP-60474_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6455_KO_GCN2_SRP346390	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.43019
CD24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557581
SLC22A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0111496
ANO6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00739118
CFTR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00687574
HTR7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00380622
KYAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556736
BRD-K49712247_NCGC00167098-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SERPINB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0113124
TPK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00811482
cefaclor-2843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-U51951544_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYBPHL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00990573
ABHD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477415
DGKZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00723424
BRD-K79090631_CGP-60474_HA1E_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tiratricol-1412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K78189262_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K83013052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59243
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8289
zomepirac-3454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02708799_GSK-1059615_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K80786583_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PTPN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552945
CD99	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671814
BRD-K12184916_NVP-BEZ235_BT20_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CBLB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0043002
BRD-K67868012_PI-103_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CELSR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00890311
CCR6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00917177
NDC80	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00846507
BRD-K51751936_Alfadolone acetate_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KDM4E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00697047
sirolimus_homo sapiens_gpl6244_gse15703	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K96799727_-666_EFO27_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11263679-41598_2024_66946_MOESM1_ESM.pdf-13-ZNF213_ZNF213	Rummagene Transcription Factor Associations 2026	1.0	null
cimetidine-1884	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0129404
SNX20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00868823
VDAC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00754488
paclitaxel_homo sapiens_gpl570_gse11552	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94012289_OSI-027_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70992537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9915
5224221-956	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76401790_JNK-IN-5A_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523286
LILRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00949171
TNFRSF13C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555987
BRD-K33086940_JAS07_007_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K88378636_withaferin-a_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PABIR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530198
SGK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00666451
IGF2BP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00344243
SGPP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00672272
BRD-K17743125_S1085_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16044155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00745
CHST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675956
FBLN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00654015
BRD-K62459624_T5212475_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC37A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00698078
BRD-K69840642_HDAC6 inhibitor ISOX_EFO27_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MUS81	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641392
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.37797
BRD-K04853698_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A75409952_wortmannin_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
verteporfin-6133	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CMTM7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568551
BRD-A19037878_trichostatin A_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573663
BRD-K69932463_AZD8055_RMGI_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
alexidine-2576	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20696416_NVP-AEW541_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K19136521_Indirubin-3?-monoxime_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DTX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00483491
ACADM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00913434
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7109
BRD-K53104784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41769
BRD-A38030642_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K61323504_SB 225002_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCIMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00728462
ACTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584901
BRD-K02822062_CT-200783_NCIH2073_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TMIGD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0112737
BRD-A49765801_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K18523449_mestanolone_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17395
BRD-A02481876_Importazole_A549_6.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DRD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00832489
BRD-K68617666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09985
BRD-K72636697_QL-X-138_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K50387473_XMD-892_MCF7_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A87137733_GSK-690693_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pilocarpine-3300	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
THEMIS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00693264
GAA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00454732
BRD-K03063480_PF-477736_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BTLA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00848172
isoniazid-1399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K15409150_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A34751532_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5993
DPYSL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051196
GJA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00455455
BRD-K39983086_loteprednol_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
DPP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00672082
NCOA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00733263
BRD-K57011718_UK 356618_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K49132774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3594
BRD-K21680192_mitoxantrone_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
beclometasone-4580	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9668
BRD-K71726959_N9-isoproplyolomoucine_VCAP_6.0_h_122.55_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SELENOM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00872866
SLC26A9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598524
ACMSD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00836692
HAPLN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00716374
sulpiride-1887	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00405038
BRD-K41895714_AS605240_SW480_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pioglitazone-7506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A15079084_phorbol-12-myristate-13-acetate (PMA)_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.42835
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1306
BRD-K53379620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36579
Fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
BRD-K53191200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5787
halcinonide-2185	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A72180425_K784-3188_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ITPK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058328
PELO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0069822
diltiazem-6710	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
diflunisal-1908	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CNTFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00739496
BRD-K93747373_HG-5-113-01_SKBR3_3_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K83972459_JWE-035_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RGL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642009
monorden-325	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42191735_buparlisib_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
0316684-0000-7052	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TNFRSF17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00744996
prenylamine-1737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00619616
ARHGDIB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00525573
BRD-K95334975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06652
PMC3197637-pone.0026348.s009.xls-TableS5_KD_ROSS2_sigTab_telamlK-Gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42918627_GSK-2126458_BT20_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K56562216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01598
DGUOK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00902131
USP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00724715
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1278
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3178
BRD-K23644387_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08502430_Angiogenesis Inhibitor_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ORC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00920335
CLDN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0113645
BRD-K53792571_Inhibitor BEC hydrochloride_SW620_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K48654774_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOWAHC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00952625
BRD-K12240312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81593
CCL22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0129006
BRD-K28360340_TW 37_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CKS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00429257
FASTK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00966952
SP140	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590209
ciclopirox-3317	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K43316594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59722
BRD-K52075040_-666_VCAP_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
zoxazolamine-1270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K88378636_withaferin-a_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65147
chlorhexidine-5403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00675987
THY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0098336
BRD-K71460915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08007
BRD-A28105619_curcubitacin I_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tanespimycin-1167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
monorden-544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A50737080_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
clorgiline-1604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mefloquine-2048	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mometasone-1746	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GLO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00835013
perhexiline-7441	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57282030_JW-7-24-1_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A64290322_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A24054354_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
response to cadmium ion	GO Biological Process Annotations 2025	1.0	null
BRD-K46439376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20317
CDK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496331
MPIG6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00532914
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9632
ATP9B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00840861
NDUFB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00404651
NOL4L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0116974
BRD-K71005143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74513
Breast cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ACAA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614717
BRD-K41311678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28141
BRD-K44427106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09163
BRD-K09129322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44664
BRD-K40221630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17234
BRD-K72636697_QL-X-138_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADAM17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00982252
KAT7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619123
camptothecin-2321	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57169635_dacomitinib_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K40490682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03995
BRD-K15716662_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZBTB16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00747824
ADH5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00416517
EDIL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00876056
BRD-K20253608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69083
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1429
PC-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.29865
BRD-K65182930_NVP-AUY922_MDAMB231_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K56244705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16485
CLEC4E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00805075
BRD-K88510285_B675700.cdx_MDST8_6.0_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K00366212_2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-8-methoxyquinazolin-4-amine KUC106573N_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LY-294002-5942	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26365
SYNCRIP_OE_GDS4596_85_human_SW480	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TLK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498688
MCFD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0104276
ZFAND2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00442097
WDR12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00743404
BRD-K84677391_-666_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K82795137_loratadine_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PKD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055407
MTCH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00932778
BRD-K61934967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06132
UO31	BioGPS Cell Line Gene Expression Profiles	1.0	0.964508
TAF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00472312
disulfiram-2215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNX17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513612
BRD-A24396574_celastrol_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K83436911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32683
BRD-A55594068_VINBLASTINE SULFATE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76539747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6332
BRD-K82109576_vincristine_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TOP2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00906283
BRD-K21595913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24497
IL36RN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00650728
KLF12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00653588
BRD-K95547711_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UBASH3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00721039
BRD-K42191735_buparlisib_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RGS16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0134246
cyclosporine_homo sapiens_gpl570_gse15935	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GPR18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00831162
BRD-K13571841_Pepstatin A_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LAMB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00784575
BRD-K28932860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21601
19797726-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
CLN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612083
GPR12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062412
BRD-A65767837_HYDROCORTISONE ACETATE_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MTNR1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0116765
BRD-K30849099_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTSW	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00782206
KCNH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00688801
KCNH7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00707904
BRD-K46419649_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A19500257_geldanamycin_LNCAP_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PGC1alpha_DEPLETION_GDS4989_283_human_A375P melanoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PCSK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582458
BRD-K88573743_A443654_MCF7_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K79090631_CGP-60474_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF365	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586525
BRD-A84189516_BACCATIN III_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBFOX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00785688
flunisolide-3747	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K34581968_BMS-536924_RMUGS_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SEMA4D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00551258
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4301
HDAC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00320994
BRD-K84990603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35696
CD40	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00422778
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1571
BRD-K45746021_CC-401_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86472598_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A55594068_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PKP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46936
PKM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677624
Molting gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
BRD-K74148702_curcumin_WSUDLCL2_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RNASE3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0104044
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.26456
DUSP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00734365
BRD-K52075040_-666_SW620_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K20259776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28008
BRD-A75409952_wortmannin_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC9B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00922539
BRD-K12539581_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Fluoro-SAHA	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33687
BRD-K81418486_vorinostat_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DHH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570277
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
BRD-A19500257_geldanamycin_MCF7_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16485616_mocetinostat_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
estradiol-1299	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K45315294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64341
sirolimus_homo sapiens_gpl96_gds2494	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K96704648_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAPK14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00521466
BRD-A75144621_digoxin_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K95035301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08419
BRD-K76713927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79764
metal ion binding	GO Molecular Function Annotations 2025	1.0	null
calmidazolium-906	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11699082-BLOODA_ADV-2023-012291-mmc1.xlsx-Sheet1-CD37_inv_corr_top100_GSE10846_CHOP_GCB_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
SPNS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102129
BRD-A25687296_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PTPMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35432
SLCO2B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00652874
gefitinib-541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
769P	DepMap CRISPR Gene Dependency	1.0	2.81914
BRD-K50563598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87385
BRD-K76401790_JNK-IN-5A_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04923131_3194_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TNNI3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549573
BRD-K89224880_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RGS8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00789086
BRD-A18497530_EI-293_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IL12B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611052
BRD-K93788137_PF-431396_HA1E_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CD86	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.010913
perphenazine-1956	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC12A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00920871
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.890881
BRD-A26095496_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPATA5L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00884387
CDCP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00856933
GAPT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047468
BRD-A76490030_K784-3131_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12762134_-666_U937_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K10513366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45005
BRD-K29728947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42589
liver	GTEx Tissue Gene Expression Profiles	1.0	1.13662
BRD-K33211335_d-3-methoxy-n-methylmorphinan_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MEOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00738099
bromperidol-7457	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
isometheptene-6524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K49630153_NCGC00183226-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K38483076_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDC42	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00447375
BTBD19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102854
BRD-K10554164_5374640_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD72	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00991263
BRD-K42191735_buparlisib_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FCRL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00625614
BRD-K33379087_tivantinib_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
C4BPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00695361
RELA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00449912
BRD-K32164935_TOLAZAMIDE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EXOSC10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054437
TARM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00833342
BRD-K39983086_loteprednol_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
naltrindole-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15358
MCM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599154
BRD-K38810814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05772
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30951
DNMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00463772
BRD-A34205397_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K54997624_BYL719_SKBR3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76723084_GR-102_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KBTBD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00742415
CHLA90	DepMap CRISPR Gene Dependency	1.0	2.64566
nicardipine-1600	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
F12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0125834
fluocinonide-4314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
iobenguane-1729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K09521750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15297
BRD-K59058766_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STK26	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00640799
HAVCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519358
SQSTM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00884115
BRD-K55238630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16599
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3718
BRD-K41859756_-666_DV90_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
alexidine-7397	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trichostatin A-5882	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
alpha-estradiol-1635	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A19633847_PERHEXILINE MALEATE_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K05951707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04888
HSD17B8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569977
TXNDC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00493551
alexidine-4721	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00529201
MADCAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102949
IGDCC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102014
CD247	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0066014
FBXW11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697606
SURF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42513
KCNJ6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706442
BRD-K01237277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04915
APEH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0106113
SASH3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0064848
NZOV9	DepMap CRISPR Gene Dependency	1.0	3.39884
VPS45	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475231
BRD-K17008822_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1305
estrone-3071	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00823191
BRD-K07877311_7811943_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41423946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16416
BRD-A15079084_phorbol-12-myristate-13-acetate (PMA)_CL34_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BCL10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0153522
BRD-K10705233_GW405833 hydrochloride_PL21_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tetraethylenepentamine-574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K55889443_rifapentine_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CACNA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00824513
STK33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00717008
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.275
BRD-K35960502_NICLOSAMIDE_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
minaprine-1888	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0496
WNT7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00638318
BRD-K92317137_-666_EFO27_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HUWE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0093416
EIF4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0113029
MYLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593185
TAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0106848
BRD-A07000685_HYDROCORTISONE HEMISUCCINATE_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42805893_HG-14-8-02_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K03816923_Rottlerin_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CROT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557271
CD36	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0101049
LRRN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00598476
HTR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00982278
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6388
ING4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00964752
BRD-K83010768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16621
BRD-K56751279_Y-39983_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FAO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
BRD-A76528577_-666_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UNC5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00535767
BRD-K57238941_NCGC00167097-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K90382497_GW-843682X_SKBR3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR3H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00592067
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2503
BRD-K77987382_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K37865504_LY-2183240_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
betulin-7454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K34839838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18332
iloprost-496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JHOC5	DepMap CRISPR Gene Dependency	1.0	3.10621
CCDC158	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0106117
BRD-K78015598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68546
BRD-K53792571_Inhibitor BEC hydrochloride_HCT116_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04853698_LDN-193189_MCF7_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NELFB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00868183
BRD-K17122222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94574
CDK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00430642
orlistat-6420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
harmine-1758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MICB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605844
tamoxifen_homo sapiens_gpl96_gds2367	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ACACA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0141322
cisplatin_homo sapiens_gpl570_gse15372	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K58772419_AZD-6482_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
BRD-K06980535_PROMAZINE HYDROCHLORIDE_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
betamethasone-1590	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
N4BP2L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00669869
BRD-K42918627_GSK-2126458_MCF7_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55420858_M9948_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K93337444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.24323
CYLD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00805357
PIK3R5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00727117
SMARCB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00418131
CEACAM8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00695727
cetirizine-4815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
halcinonide-7379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K10906552_7887507_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LY6G6F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00706122
BRD-K42191735_buparlisib_HS578T_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DAB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00836433
VSIG8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0087614
ITGB7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00512347
ABCD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737586
SMYD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00621933
NCAPH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00577734
tubocurarine chloride-1738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MEST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00733169
RETREG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618576
copper sulfate-438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYO1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675022
MUC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33433
HSD11B2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0109615
BRD-A19037878_trichostatin A_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TC205	DepMap CRISPR Gene Dependency	1.0	3.09476
NPM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00820269
DALRD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0121473
BRD-A47816767_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81142122_STK249718_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLIC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00986702
SERPINI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059995
CD300LD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00833144
CPNE7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558456
tanespimycin-6177	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00739065
HNRNPM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00767039
NCOA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573036
mt3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.84
acebutolol-1911	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K95196255_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K54694941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14527
LITAF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00800822
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6096
BRD-K95138506_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K05653692_DL-PDMP_SKMEL1_6.0_h_64.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K52522949_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CYP3A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0121436
cellular response to metal ion	GO Biological Process Annotations 2023	1.0	null
BRD-K88573743_A443654_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K40175214_torin-1_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K88378636_withaferin-a_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42191735_buparlisib_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CASP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00718894
CLIC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00802498
BRD-K85908443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1923
BRD-K02708799_GSK-1059615_HEPG2_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K18645499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75454
ethambutol-1900	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IDUA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102922
VNN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00502101
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
AKT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0040906
BRD-K01976263_Emetine Dihydrochloride Hydrate (74)_HEPG2_6.0_h_0.63_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKNBE2	DepMap CRISPR Gene Dependency	1.0	4.51689
BRD-K47415214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57077
BRD-K59469039_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ENPEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0082764
BRD-K10545066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09799
BRD-K21215763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60505
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31743
LIF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.011263
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8581
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
SLC6A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641447
TREM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00794993
IL12A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0067269
EPCAM_OE_GDS4887_342_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K99964838_S1014_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9368
BRD-K48488978_YM-201636_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GUCY1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00705298
CHKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0109527
disulfiram-6210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTF2IRD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02323
BRD-K67830713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35005
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.822
BBC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00565393
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7433
ICC2	DepMap CRISPR Gene Dependency	1.0	2.39488
ERMAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00723242
SCN3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00869317
PMC9377669-tx1c00392_si_002.xlsx-Ascorbic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
PUS10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00730375
LAX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00578973
BRD-K61269089_Daphnetin_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
doxorubicin_homo sapiens_gpl96_gse2715	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
T-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.298
EPHB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00654709
MAPK9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00736238
MEX3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00637125
BRD-K48113109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43135
amikacin-6715	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRCA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00644354
CYP20A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00806876
BRD-K65729622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79472
TBX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00789973
demecarium bromide-6269	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-L-Thyronine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A89907244_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5291
HTC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
KPNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0138656
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92291
GPRC6A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051843
BRD-A71390734_4-Demethoxydaunorubicin hydrochloride (65)_MCF7_24.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H4C5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0121715
CREB3L4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00757447
MAPKAPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00350726
ciclopirox-5023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TNFSF15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00665654
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
TNFSF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00788402
BRD-K62154563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06666
BRD-K66032149_VU0365117-1_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RIT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00439736
BRD-A73741725_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DOCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00545847
FPR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507905
BRD-K64890080_BI-2536_LNCAP_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PIK3CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00818822
IFNA10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060517
BRD-A39996500_radicicol_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K26760349_HG-9-91-01_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K97764662_P2499_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3954
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
CHI3L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00868776
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06893
BRD-K18711687_NCGC00184891-01_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CSGALNACT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00793293
GPI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00799588
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9978
BRD-K49552510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61147
CAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0106484
PSMB9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716361
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3664
BRD-K67578145_GDC-0879_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LTB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0114377
BRD-A93236127_DIGITOXIN_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IL31	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00491496
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1005
FGG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539656
SPIB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00739542
BRD-K70511574_sunitinib_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K06279388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13719
BRD-K49630153_NCGC00183226-01_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K96076993_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HTR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.005736
BRD-K92428232_GSK-461364_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57546357_PRUNETIN_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TSSK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0072223
SKIC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537738
BCOR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00830604
BRD-K67578145_GDC-0879_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55187425_ON-01910_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K84595254_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
XCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490942
BRD-K60353472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17525
BRD-A79768653_sirolimus_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K79404599_enzastaurin_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K23673040_(Naphthalen-1-ylamino)-acetic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VSIG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049733
HHEX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00543042
meclocycline-1341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AKR1C3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00360197
GALK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00851828
CD200R1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00801188
CD244	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601366
AMPD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00856531
LSR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533488
BRD-K03015355_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CERS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00791394
BRD-U22633929_XMD11-85H_BT20_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K34209560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36037
BRD-K52075040_-666_SKM1_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dexamethasone-2079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMYD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537617
BRD-K70642949_GSK-2334470_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ANKRD44	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534818
BRD-K72636697_QL-X-138_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IFIT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00648813
PFKL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00760992
BRD-K12539581_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PIP4K2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00535017
ELOVL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00877123
TRPM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00824943
BRD7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706798
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.853
BRD-K23282736_-666_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83033
BRD-K49371609_528116.cdx_PL21_6.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12202458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00058
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
ACP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0135517
oleandomycin-1935	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EED	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00927001
DPP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00810872
FCRL6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00851481
TEX14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564749
TLR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00906239
BRD-K29983336_rondual-kinase-inhibitor_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68174511_torin-2_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76401790_JNK-IN-5A_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K64890080_BI 2536_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04853698_LDN-193189_SKBR3_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K17086338_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NDUFA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00500826
TMEM117	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00438917
PMC9377669-tx1c00392_si_002.xlsx-Thalidomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45223163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07716
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8569
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.296
GPAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39925
CD81	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00438076
ORAI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00459243
BRD-K95023134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15268
CEP55	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00813374
BRD-K85402309_dovitinib_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K74148702_curcumin_SNUC4_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
quinethazone-4529	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K63606607_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC29A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00709487
TAOK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061209
PID1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066394
exisulind-309	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72303
mifepristone-1569	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K90382497_GW-843682X_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STRADB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585069
clioquinol-5258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GNMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0114306
TRIB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00654464
BRD-K81795824_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12184916_NVP-BEZ235_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
paclitaxel-2043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K05402890_NCGC00165289-01_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TLR6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673354
GABRQ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00949816
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6369
BRD-K64890080_BI-2536_HT29_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Lithium_Chloride-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GPBAR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677428
CHRM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00545528
pentetic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69635
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	3.96868
ASAH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00370287
BRD-U86922168_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
response to copper ion	GO Biological Process Annotations 2023	1.0	null
SEMA7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00679378
BRD-K59470558_MLS-0315848.0002_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pioglitazone_homo sapiens_gpl570_gds4132	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K71726959_N9-isoproplyolomoucine_PL21_6.0_h_122.55_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
S-propranolol-5444	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16698502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11482
TCF7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0106067
TESPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00787468
BRD-K40675267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38633
STH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0107377
BRD-A18328003_GDC-0980_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COX6A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552687
BRD-K49865102_PD-0325901_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K74632893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.82628
KMT5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0082096
HEATR9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056954
BAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
BRD-K02788568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0149
BRD-K99532291_SPB02303_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95435023_PHA-665752_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TNFRSF10B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00667172
BRD-K89093471_VU0418934-2_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68065987_MK-2206_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540794
BRD-K37846922_GR-207_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
risedronate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11843
BRD-A29082194_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EPOP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605377
OGDH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00438896
BRD-K04317371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19925
UCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00660614
BRD-K33379087_tivantinib_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAB31	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00713197
PMC9377669-tx1c00392_si_002.xlsx-MethylMerc-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFA13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0103127
STAC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00452803
BRD-A45498368_WYE-125132_BT20_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77908580_S1053_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AIF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74301
BRD-K14695950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75122
BRD-K82805160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30889
BRD-K15916496_clotrimazole_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GCSAML	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00854171
CAV3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00712579
BRD-K70511574_S1485_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K52321331_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A41450521_Tosufloxacin hydrochloride_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AP3D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541568
CD83	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0127282
BRD-K14696368_16759925_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cellular response to copper ion	GO Biological Process Annotations 2025	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1063
CYP2B6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619841
prenylamine-2886	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PCSK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00747905
CDK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0125293
BRD-K34960081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47309
cellular response to copper ion	GO Biological Process Annotations 2023	1.0	null
BRD-K46056750_AZD-7762_A549_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K35240538_methylprednisolone_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K17075857_CHLOROXINE_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NUPR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575067
BRD-K79404599_enzastaurin_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
phenoxybenzamine-6451	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZAP70	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0117853
MEP1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00397932
bergenin-3467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K28349636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02779
BRD-K68732617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31986
BAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00676901
MCM10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00899851
IGROV1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.948387
BRD-K68336408_Tyrphostin AG 1478_HEPG2_6.0_h_56.78_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
1,4-chrysenequinone-1773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DMPK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00627782
MYOM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685716
BRD-K09549677_Mibefradil dihydrochloride_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K06009608_-666_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A58767537_afatinib_HS578T_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NPY5R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664512
GRIN2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00973028
SCN4B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059136
BRD-K85559506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95001
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNF1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00701
BRD-K68823900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.82114
SLC16A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0101024
APOA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496386
BRD-K01166365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54667
BRD-K39649774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74442
MAG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00892144
SPINK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.010528
BRD-K59638683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00492
ABCA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0111071
BRD-A16700644_ISOXSUPRINE HYDROCHLORIDE_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536407
BRD-A15079084_phorbol-12-myristate-13-acetate (PMA)_NCIH2073_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PTPN22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660564
BRD-A28105619_curcubitacin I_COV644_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549966
BRD-K67868012_PI-103_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SAMD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00621975
tretinoin-6243	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BTG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00913049
BRD-K01292756_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68174511_torin-2_HS578T_3_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2293
BRD-K50140147_NVP-TAE684_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60842
BRD-K22503835_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K47869605_podofilox_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A00420644_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HTR2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0107484
IFIH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0117988
BRD-K17525686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36358
BRD-K99455613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1503
BRD-K74651253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77274
BRD-K64890080_BI 2536_JHUEM2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sulfadiazine-1810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LY86	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00702025
GOT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00820985
BRD-A06929388_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12502280_TG101348_A375_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ADM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00976645
BRD-A45498368_WYE-125132_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-U60236422_WH-4-025_SKBR3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ABCD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00751343
DTYMK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00519807
tacrine-2633	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K20000640_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K24743998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17887
BRD-K54256913_MK-1775_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PSAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585455
CPOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00911819
IMPDH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525459
BRD-A39996500_radicicol_MCF10A_3_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ANXA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0128274
metformin-61	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.509
BRD-K16798053_ST4029573_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68174511_torin-2_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K11072542_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GUK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0123884
ARFRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0040643
CYB5R3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00638189
betamethasone-6728	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K36055864_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42125900_S1148_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCN3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0108142
BRD-A39996500_radicicol_SKBR3_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MHHES1	DepMap CRISPR Gene Dependency	1.0	2.793
BRD-K45746021_CC-401_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A06276885_N-Benzylnaltrindole hydrochloride_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11459
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.891
BRD-K43389698_BMS-387032_SKBR3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75842461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72045
CDC25A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00426351
BRD-K78599730_manumycin A_SW620_6.0_h_9.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
homatropine-1848	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDKAL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517868
BRD-K51816706_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
C5AR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697469
BRD-K64314806_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
E2F7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00711456
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58787
BRD-K31342827_GF-109203X_MDST8_6.0_h_12.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00718861
HNRNPAB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594149
TPRKB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555523
BRD-K02607075_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PAK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671378
BRD-K62493605_JAS07_009_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CNTN5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564374
BRD-K99252563_QL-XII-47_LNCAP_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K95138506_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49669041_BX-912_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLEC11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.012129
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7337
DLG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0084542
PDLIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0044719
BRD-K31215362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51428
BRD-A54927599_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42918627_GSK-2126458_MCF7_3_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STK32C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605774
FGL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00597454
BRD-K88573743_A443654_PC3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EDN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00389658
CBX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671548
PBMC cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.295
LMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660639
ITGB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00692867
RSC1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00650794
BRD-A02481876_Importazole_MCF7_6.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KCTD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00723219
BRD-K70511574_sunitinib_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A19037878_trichostatin A_NCIH2073_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GMNN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555926
BRD-A24643465_homoharringtonine_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PDE4DIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00827229
BRD-A49680073_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLOCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588496
EDA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575117
TNFRSF1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00943589
BRD-K42333498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07707
NUDT19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513673
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76829
FBN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497213
BRD-K12184916_-666_HT115_6.0_h_0.63_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K06750613_-666_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K14765469_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K25394294_oxaprozin_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77987382_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A62182663_YK 4-279_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A34806832_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sirolimus-1001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LYSMD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0126145
LY-294002-4463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
meclofenamic acid-1445	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
astemizole-1365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A03216249_mepivacaine_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
BRD-K43389698_BMS-387032_A549_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PHKG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00897477
SC-58125-542	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51443908_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33347
APOB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00815125
BRIX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00822419
KIF19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598109
BRD-K95171874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32595
BRD-K33583600_ISOLIQUIRITIGENIN_LOVO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49865102_PD-0325901_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K03406345_azacitidine_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.0812
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13394
ARID1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00878205
CARD11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660445
BRD-A81530502_8009-7630_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MARCO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00538332
BRD-K40410846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09542
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5792
BRD-K59184148_SB 216763_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00659773
BRD-K95018971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40841
SKP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0059745
CD300A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616779
PYCARD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054146
BRD-K49810818_S-8599_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PAPOLA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00713566
BRD-K15087476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11019
nordihydroguaiaretic acid-524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NEU2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00650695
BRD-K59657378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14821
BRD-K45136330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32647
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13617
BRD-U51024685_HG-6-64-01_HEPG2_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
valproic acid-1060	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K44779798_miglitol_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42191735_buparlisib_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53414658_-666_A673_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LDLR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00413789
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45267
TM4SF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00668391
NPTN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484747
BRD-U60236422_WH-4-025_MDAMB231_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ROBO3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00645829
piperlongumine-1764	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K82024598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00406
BRD-A79768653_sirolimus_SKMEL28_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mestranol-4208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIRT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526845
BRD-K09661167_OSSK_645683_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68174511_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K01877528_TL_HRAS26_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Favipiravir-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
SMOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00991383
KCNC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00683522
ZEB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00855766
BRD-K46161579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00519
mesalazine-124	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LIG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00846005
TTBK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00692812
HAVCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00683313
PIGH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00737515
BRD-K03458571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19537
SIRT7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00350255
PMC9377669-tx1c00392_si_002.xlsx-Carbamazepin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20285085_R406_RMGI_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A56592690_PX12_RMGI_6.0_h_30.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
khellin-2004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24678
BRD-K62363391_dapsone_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K15940471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48732
BRD-K04853698_LDN-193189_MCF10A_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A79768653_sirolimus_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZFP91	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00565563
chlorpropamide-141	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.919764
BRD-K67868012_PI 103 hydrochloride_EFO27_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EZH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484624
RH30	DepMap CRISPR Gene Dependency	1.0	2.00653
ETNK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00654425
TARDBP_KD_GDS3730_118_human_HEK293E	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TRPM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523957
BRD-K95080525_NCGC00183401-01_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K74129999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30823
cotinine-2011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K70281171_U 99194 maleate_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VSIR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00551557
BRD-K53913732_SB 408124_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ALOX5AP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00613288
BRD-A27640568_5846833_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
(-)-catechin-1101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CD8B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00686402
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2193
BRD-K74430258_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RNASEH2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00683653
BRD-K02066524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16459
NCF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590886
TYMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00645488
TLR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00683834
colforsin-783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59693
BRD-K68065987_MK-2206_SKBR3_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76401790_JNK-IN-5A_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K65086352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40147
BRD-K02708799_GSK-1059615_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
(+)-chelidonine-1786	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PSG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00539652
RHEBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00505287
BRD-K61323504_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K44100512_KIN001-043_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ATM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0107757
GUCY2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618775
BRD-K25731886_-666_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
imatinib-366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCDC77	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063424
BRD-K22839533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41485
apomorphine-1923	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02130563_S1030_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ANGPTL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0128175
BRD-K19220233_JNK-9L_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GBP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00919089
BRD-A23637604_oxymetholone_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12743035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20568
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2257
BRD-K99749624_linifanib_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lidocaine-1999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LTA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00666753
FURIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0080702
BRD-K84762162_-666_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K28810861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26804
LOXL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00412512
IFNA14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00481836
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32687
ascorbic acid-1610	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PLCG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00717379
BRD-K55187425_ON-01910_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
estradiol-121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K52665916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65587
BRD-K93109423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05129
tranylcypromine-1417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GP5D	DepMap CRISPR Gene Dependency	1.0	3.3512
BRD-A87387433_cefpodoxime proxetil_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9134
BRD-K71823332_S1297_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0122409
isoflupredone-1873	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAMSTR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599806
CASP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00975144
UCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27677
BRD-K03861440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09189
SLC16A10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605439
NMUR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00712722
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6742
TUBE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523474
BRD-K76401790_JNK-IN-5A_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HTR1E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0109467
BRD-K78828094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17878
BRD-K42918627_GSK-2126458_BT20_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
isoxsuprine-1985	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATF6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00461704
EBI3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623552
BRD-K81418486_vorinostat_AGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K69624346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12451
P3H1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00995287
genistein-1176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K01877528_TL_HRAS26_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K25187028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.94084
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44147
BRD-K40126748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20917
NCIH3122	DepMap CRISPR Gene Dependency	1.0	3.79354
CHSY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00940227
BRD-K39326623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22097
BRD-K56343971_vemurafenib_MDAMB231_3_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K83963101_MLN-8054_PC3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fluticasone-4011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K61323504_sb 225002_A375_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K74842791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73492
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8747
BRD-K08799216_pelitinib_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
prednisolone_homo sapiens_gpl570_gse32962	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K89093471_VU0418934-2_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K61052964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44534
BRD-K81169441_cerivastatin na_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
S1PR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584761
mefloquine-1364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GCH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00462897
FAM47E-STBD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585806
BRD-K80431395_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RMI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693986
BRD-K89732114_-666_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K89930444_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GCT	DepMap CRISPR Gene Dependency	1.0	2.09021
BRD-K04853698_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Fetalliver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11459
REL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596924
UBA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00699765
PTGS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00869911
BRD-K39844985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25274
BRD-K29649571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79812
celecoxib-377	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K58299615_Ro 90-7501_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WDR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00578376
BRD-K59369769_tozasertib_MCF7_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CISD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0050204
geldanamycin-1008	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NELFE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0136455
TWF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060125
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66077
CDK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00729911
TAPBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565388
BRD-K98824517_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92804652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07715
BRD-K93747373_HG-5-113-01_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02822062_CT-200783_NOMO1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Ranitidine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BTBD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00822676
BRD-K07667918_linsitinib_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23913458_COUMARIN_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tribenoside-6328	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A82096673_KUC103428N_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRKCG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0142367
Liver bud hepatic cell_Liver_Human	CellMarker Gene-Cell Type Associations	1.0	null
H4C9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00609838
pirinixic acid-368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
triamcinolone-5835	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STK17A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00764348
BRD-K08109215_I-BET_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF646	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00909113
HINT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.005407
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
ARHGAP15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503518
UBD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0103578
BRD-K15108141_gemcitabine_VCAP_24.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHRNB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620798
BRD-K91900765_S1458_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A71390734_4-Demethoxydaunorubicin hydrochloride (65)_SKM1_6.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KIF3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00499079
troglitazone-504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K10705233_GW405833 hydrochloride_HEPG2_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NDUFA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00460981
NPC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00731971
BRD-K78238858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76487
HM13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569401
clioquinol-5623	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDE4D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0111342
ACKR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00770508
GYPE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00918055
FGFR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583523
TMEM258	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00915536
BRD-K13411423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.92673
TMIGD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00952466
SDHC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00841938
NDUFB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47722
BRD-K05104363_PD-184352_MCF10A_3_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CKS1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0114773
TSPAN10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00883176
gefitinib_homo sapiens_gpl570_gse20854	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PCYT1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00701178
PEAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0112915
BRD-A19037878_trichostatin A_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K79259477_KIN001-265_HEPG2_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A61825514_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81418486_vorinostat_SKM1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04623885_BIBR1532_A673_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K38265819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02225
CD33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560427
U87MG	DepMap CRISPR Gene Dependency	1.0	3.39741
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.53
perhexiline-5501	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16604360_R(-)-2,10,11-TRIHYDROXY-N-PROPYL-NORAPORPHINE_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K76492619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9377
sertaconazole-3550	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
flumetasone-3712	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Laryngotracheitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
SLC7A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00486603
minoxidil-1496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SYK_DEPLETION_GDS3609_36_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
betulin-3513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
betulin-2952	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC52A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00752111
496100490_HIP_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.1662
BRD-K86027709_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IGFBP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0051131
PMC9377669-tx1c00392_si_002.xlsx-Famotidine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
ARHGEF25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612184
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.97
BRD-K30284601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.11632
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6854
BRD-K69932463_AZD8055_HT115_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HO1U1	DepMap CRISPR Gene Dependency	1.0	2.91294
BRD-K66792149_-666_A375_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pipenzolate bromide-2719	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K04005364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11507
PMC9377669-tx1c00392_si_002.xlsx-Chlorophenamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35960502_NICLOSAMIDE_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5633
BRD-K72414522_AZD-5438_MDAMB231_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K39944607_32937_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PGD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641492
CHAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642459
NEIL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0078766
BRD-K54256913_-666_RKO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12123029-41598_2025_3625_MOESM1_ESM.pdf-1-EMX2_EMX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A19633847_PERHEXILINE MALEATE_COV644_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NEK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057966
BRD-K02708799_GSK-1059615_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BLTP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568275
BRD-K60693111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51272
BRD-K12787259_CX-5461_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDC42BPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664722
BRD-K95196255_-666_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94012289_OSI-027_MCF7_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
BRD-K03063480_PF-477736_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45924
UBQLN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0080961
BRD-A39996500_radicicol_MCF10A_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K63998843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20836
RFX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057617
AIF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0144108
BRD-K24681473_S1130_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04336022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.84791
BRD-A25143711_HYDROCORTISONE VALERATE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disulfiram-5729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDCA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0110744
TNFRSF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0078087
GTPBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0130102
HNMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664862
CEACAM20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00780267
IL23A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0119831
IL6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00596722
SRM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0100628
BRD-K99749624_linifanib_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K29503289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10309
ADAM12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00516071
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K78385490_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mestranol-3008	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PHTF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055697
BRD-K02130563_S1030_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.2386
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.163
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0459
BRD-A19037878_trichostatin A_RKO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IL15RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601079
NFKBIZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00860772
BRD-K84090286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.44636
SEMA3D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00766001
PMC9377669-tx1c00392_si_002.xlsx-Paroxetine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
HLA-DQB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522221
MSTO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00800034
BRD-K90382497_GW-843682X_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSTO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0070588
BRD-K09963420_saquinavir_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NXPE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00742309
CEACAM18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0064433
BRD-K88573743_A443654_BT20_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VMP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00735687
BRD-K02708799_GSK-1059615_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HEK 293T	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.965508
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.00402
clobetasol-4497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.496
sodium phenylbutyrate-502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ITGAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00667363
FNBP1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00778668
GRM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00760183
PDE4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00789643
TNFSF13B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00911113
BRD-K44861255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70495
BRD-K02407574_Parbendazole_A549_24.0_h_0.31_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K06792661_Narciclasine_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RIPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00393301
prenylamine-5489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC22A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00688547
SEC14L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00743969
BRD-K45859834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20671
CGAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0071382
MRPL16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00593241
BRD-A75409952_wortmannin_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bexarotene_homo sapiens_gpl96_gds2777	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PM20D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00913006
estradiol-365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K33379087_tivantinib_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
etodolac-1407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A19037878_trichostatin A_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RFXANK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00968789
BRD-K99498722_S1176_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A94377914_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K73635724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.6736
PRDX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00640568
MELHO	DepMap CRISPR Gene Dependency	1.0	2.37565
PMC9377669-tx1c00392_si_002.xlsx-Methicilin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A75172220_HYDROCORTISONE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
MYO3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568638
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3088
496100546_TCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.80788
BRD-K82928847_rocilinostat_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K88583132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59833
BRD-K89000000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1822
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
NKX3-1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0127716
BRD-A55594068_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CFL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00884597
SNU626	DepMap CRISPR Gene Dependency	1.0	3.52663
BRD-K42814713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.49828
ARNT::HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2212
BRD-K03116010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26898
BRD-K12867552_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MARCKS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00809909
BRD-A15530910_SDZ 21009_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K18190982_COT-10b_A549_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IRAK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600835
ZEB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00881445
ARL5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00855679
noretynodrel-1860	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K05653692_DL-PDMP_AGS_6.0_h_64.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MALME3M	DepMap CRISPR Gene Dependency	1.0	3.43026
ASAH2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633271
ACADSB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00476372
SCN11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601157
BRD-K65506286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03538
KCNK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00488314
BRD-K98143437_SB-239063_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dexamethasone-123	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A35869383_ibrutinib_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SLC4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00708479
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3034
BRD-K44956383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5108
BRD-K57238941_NCGC00167097-01_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00826366
TRAPPC13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0078119
BRD-K70397964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03592
propafenone-1722	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
alpha-estradiol-122	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LU99	DepMap CRISPR Gene Dependency	1.0	2.37083
todralazine-1677	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K49712247_NCGC00167098-01_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
enalapril-7026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0124307
KLRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0107354
BRD-K69852452_F1566-0341_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KURAMOCHI	DepMap CRISPR Gene Dependency	1.0	3.35444
0198306-0000-7064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K54233340_Dorsomorphin dihydrochloride_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81418486_vorinostat_A673_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
Metallothionein, vertebrate	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K88510285_B675700.cdx_SW480_6.0_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OPRL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657125
RUNX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059682
PMC9377669-tx1c00392_si_002.xlsx-Doxylamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A24396574_celastrol_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100373_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.7186
BRD-K42191735_buparlisib_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99252563_QL-XII-47_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K56428170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63791
BRD-K76401790_JNK-IN-5A_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CYP2C19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694107
NDUFB9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515708
mefloquine-2210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K39503511_MK-0591_A549_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
MYLK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00591471
BRD-A06909528_MLS-0315871.0001_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RGS14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00811904
BRD-K11844807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.82426
SPOCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.014232
clioquinol-4663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IFNL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00499219
CD276	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00750885
BRD-K12184916_NVP-BEZ235_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00691581
DNAJC5G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685528
BRD-K67868012_PI-103_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68174511_torin-2_SKBR3_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CIITA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498745
NKX2-6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542024
SPPL2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00732504
PMC9377669-tx1c00392_si_002.xlsx-Vismodegib-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
resveratrol-841	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68336408_Tyrphostin AG 1478_RMGI_6.0_h_56.78_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
isoconazole-1372	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H4C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17355
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.03641
BRD-K25485361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32347
PMC9377669-tx1c00392_si_002.xlsx-Magnesium_Cl-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
TENM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00604713
EGR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00841578
TMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3159
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CACNB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00930774
ST8SIA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00883944
PMC9377669-tx1c00392_si_002.xlsx-Buspirone-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68336408_tyrphostin-AG-1478_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DAPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00999351
PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40175214_torin-1_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20984459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40046
CCNH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619234
BRD-K14109347_LY2603618_A549_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A85891951_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RSBN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00532491
CFAP46	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00626075
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0026
BRD-A39230911_Chlorphensin carbamate_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K79090631_CGP-60474_HT29_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K14914284_NCGC00187898-02_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SAP30	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642679
BRD-K00816165_-666_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10809641-DataSheet3.pdf-260-MSANTD4_MSANTD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Folic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
CFHR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00793331
BRD-K26767475_NCGC00183255-01_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0199
CTLA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00934075
TNFAIP8L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00705037
BRD-K03804563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16188
BRD-K03901181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01324
LY9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00717246
fendiline-1573	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FGA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00743141
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15779
PRL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598878
BCL2L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00382171
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9775
CD68	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.011161
BRD-K09951645_dabrafenib_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K39887954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42826
CACNG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00613181
1,5-isoquinolinediol-543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fludrocortisone-4342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF683	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00854162
BRD-K99827210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72049
BRD-K55187425_ON-01910_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K65257143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37453
BRD-K13533483_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CARD14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058762
BRD-K81418486_vorinostat_EFO27_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99530743_NCGC00242340-01_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100473_TCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57806
PTAFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564546
WDR72	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00643644
BRD-K06792661_Narciclasine_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55187425_ON-01910_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
diltiazem-2032	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GJB7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00907333
EMD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0104997
BRD-K64072266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28655
ATF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30312
TRAF3IP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00581887
BRD-A19037878_trichostatin A_RMGI_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4315
BRD-K12502280_TG-101348_MDAMB231_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K24132293_piperlongumine (HPLC)_COV644_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DBH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00736344
DDRGK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00574977
azacyclonol-1520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99818283_PIK-90_RMGI_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
metformin-3	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100558_PCx_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.8837
BRD-K69536411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.62186
BRD-K87191742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14267
BRD-A63949900_NCGC00238536-01_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A06664848_-666_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rifamycin-sv	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10985
hexetidine-5420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55606442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59416
SEPHS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00746936
BRD-K76135327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16112
PILRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00683249
brinzolamide-3230	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C1QC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594526
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0104805
GATA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00681207
BRD-K78867378_mw-A1-12_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53903639_480743.cdx_A673_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
INO80	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0127699
RIDA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00556037
BRD-K11752384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38918
PMC9377669-tx1c00392_si_002.xlsx-Dextrometh-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
RPE1SS6	DepMap CRISPR Gene Dependency	1.0	2.36015
strychnine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84384
sulfacetamide-1817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
haloperidol-1955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K21680192_mitoxantrone_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Metallothionein domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K67566344_KU-0063794_HT115_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5919
BRD-A05680309_MLS-0390982_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC44A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00707928
CD5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611364
BRD-K43782924_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
BRD-K16406336_METHYLENE BLUE_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23363278_CYT997_MCF7_24.0_h_1.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADRA2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00856466
CLDND1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564796
HLX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602016
BRD-K19220233_JNK-9L_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67442425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71273
CALCR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00624268
TNFR/NGFR cysteine-rich region	InterPro Predicted Protein Domain Annotations	1.0	null
TSGA10IP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00723986
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1163
BRD-K17349619_HLI 373_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A19037878_trichostatin A_A673_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AKR1C4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00735136
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7399
SERPINC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054689
BRD-K37865504_LY-2183240_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFKBIA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594515
GPR143	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00826834
INSC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00773103
OAZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477396
LRRC8C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0113246
BRD-K16798053_ST4029573_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K87927290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09806
TMK-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.12703
GSTK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00668505
ARID1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00505974
AGMAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533692
BRD-K76188144_N-Oxalylphenylalanine_VCAP_6.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DHFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542979
HIPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00842526
tetrandrine-7178	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A19037878_trichostatin A_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TARBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00630676
BRD-K69840642_HDAC6 inhibitor ISOX_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20285085_R406_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K09250623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74509
Hepatoma ascites cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
BRD-K59222562_NCGC00185984-01_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81605832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5007
BRD-K70642949_GSK-2334470_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6478
BRD-K61662457_CAY10594_RMUGS_6.0_h_20.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K14888893_minoxidil_A673_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51697562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24875
BRD-K68065987_MK-2206_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41189799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82305
BRD-K42805893_HG-14-8-02_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ENTPD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.011613
BRD-A19037878_trichostatin A_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1669
BRD-K02407574_Parbendazole_HT29_24.0_h_0.31_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K95648552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15131
SLC6A11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633052
BRD-K34205220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01803
RENBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636949
BRD-K34452916_FU_JMBII127B_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A36275421_MW-ras12_THP1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRKCE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00740449
PIM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578624
TLR10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.01147
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32719
BRD-K71726959_N9-isoproplyolomoucine_HEPG2_6.0_h_122.55_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8292
Mitotic spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.35
BRD-A19500257_geldanamycin_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7199
WT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618888
BRD-K69840642_HDAC6 inhibitor ISOX_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K30707190_PNU 74654_A549_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A62025033_temsirolimus [CI779]_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7143
BRD-K87142802_veliparib_PC3_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K36363294_I-BET151_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NAGLU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00635538
triamcinolone-2078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0091
BRD-K12411112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72794
AMG-900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59973
FGF14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00788491
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
ASXL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0038307
FUT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513037
WM3211	DepMap CRISPR Gene Dependency	1.0	2.19863
PMC9377669-tx1c00392_si_002.xlsx-9-cis_retinoic_acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76401790_JNK-IN-5A_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42918627_GSK-2126458_SKBR3_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SBK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051582
PMC9377669-tx1c00392_si_002.xlsx-Sucralose-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60238606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96824
BRD-K34370545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44639
BRD-A79465854_auranofin_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
B9D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614239
BRD-K49669041_HY-11005_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COX5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614347
benzydamine-7169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K84924563_6-diazo-5-oxo-l-norleucine_A673_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EVI2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00610655
BRD-K68588778_6942543_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K61092554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23915
BRD-K55053106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76013
3-aminobenzamide-590	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K74148702_curcumin_PL21_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MSI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671116
dexverapamil-164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49865102_PD-0325901_MCF10A_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ATP1A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00898957
AADACL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00772475
IGSF9B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00724943
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.15425
BRD-K84955386_hyperoside_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53732802_VU0365118-1_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCABER	DepMap CRISPR Gene Dependency	1.0	2.04397
triflupromazine-1855	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K23412959_NCGC00165188-01_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
F11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00811837
MTMR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588374
prenylamine-5070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99818283_PIK-90_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97534490_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A87137733_GSK-690693_HS578T_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1713
BRD-K53417444_OTSSP167_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular response to cadmium ion	GO Biological Process Annotations 2025	1.0	null
TPBGL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00920264
TMCO3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703098
PTGFRN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00927236
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7771
CACNA1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00611454
BRD-K09138889_KUC104131 KUC104131N_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dihydrostreptomycin-2237	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JAM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578024
NFKBIE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0105546
BRD-K28296557_Akt inhibitor IV_EFO27_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MPEG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0149027
NEDD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00435483
BRD-K71631414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.564
BRD-K95573463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48049
BRD-K89224880_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K69480055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36061
BRD-K18861610_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT1197	DepMap CRISPR Gene Dependency	1.0	2.85043
BRD-K76899562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74248
BRD-K12343256_trametinib_MCF10A_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.54
BRD-K19216856_(-)-Gallocatechin gallate_EFO27_6.0_h_88.8_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K63770300_NCGC00188740-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLRD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054481
BRD-K99028283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33584
G6PD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00696262
PIK3R1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603599
DAPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600942
ACVR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622344
FAM89B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.007594
alpha-estradiol-990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A12230535_Nutlin-3_NCIH1694_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K88573743_A443654_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7281
chlorhexidine-6302	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NME2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00817257
BRD-K19295594_-666_HEPG2_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ACOD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00836888
BRD-U60236422_WH-4-025_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gentamycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25555
LILRA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00796937
CT45A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00919245
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9008
CREBRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96022
HTR2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00780816
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3263
NFE2L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0130745
BRD-K43295075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54473
SKMM2	DepMap CRISPR Gene Dependency	1.0	2.40412
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.130871
mecamylamine-7023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K49328571_dasatinib_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	3.3309
16-phenyltetranorprostaglandin E2-7541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JAK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00801447
SCNN1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00773591
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
BRD-K54095730_CMPD-1_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6861
BRD-K84203638_4-[(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy]-N-(4-methylpyridin-2-yl)butanamide_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12539581_NOCODAZOLE_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K44640865_VU0365121-1_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FUT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00779212
BRD-K51189903_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AXL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0118144
PSG9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00844246
EPHA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00722784
BRD-K81418486_vorinostat_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD28	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00605741
BRD-K72646819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13845
BRD-K24681473_S1130_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0104737
NOD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00460578
BRD-K55113501_Digoxigenin_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NLRC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598721
BRD-A75409952_wortmannin_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LTN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00809716
LAPTM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00942395
BRD-K67813189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46542
BRD-K93623501_NCGC00186101-01_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KCNC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0105605
TMEM229B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0130706
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08872
BRD-K75143842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4188
BRD-K43330982_JTE 013_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZBTB7B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518641
ELK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552079
BRD-K74305673_IMD 0354_A673_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MIR122_OE_GDS3470_573_human_Embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HRH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658065
CDH6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00700075
BRD-K37865504_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dobutamine-1589	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OUMS23	DepMap CRISPR Gene Dependency	1.0	2.83701
EMTOKA	DepMap CRISPR Gene Dependency	1.0	2.33224
DGKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00904281
Frontal sinusitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
Neoplasms	CTD Gene-Disease Associations	1.0	1.10665
BRD-A71390734_4-Demethoxydaunorubicin hydrochloride (65)_OV7_6.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MEL290	DepMap CRISPR Gene Dependency	1.0	3.5083
SDS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00912962
ITGA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.008579
PDE1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00746616
suloctidil-1297	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59434830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16853
TSSK1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00665249
BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_H1299_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IDO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549019
BRD-A68888262_azelastine hcl_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02113016_olaparib_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AMZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00700994
cellular response to metal ion	GO Biological Process Annotations 2025	1.0	null
BRD-A52886023_A8674_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FPR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0126759
CAV2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00978512
S100A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00828205
BRD-K63024248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36701
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3452
astemizole-4471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K88378636_withaferin-a_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K98548675_Parthenolide_SKM1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU449	DepMap CRISPR Gene Dependency	1.0	2.85622
BRD-K83705009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48861
NEK10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677491
BRD-A45889380_QUINACRINE HYDROCHLORIDE_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAOV-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.12703
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2817
BRD-K51575138_TPCA-1_AGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K50841342_PAC 1_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PAPSS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00453646
PIK3CD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00935699
BRD-K44265418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42484
BRD-K20023110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02993
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71068
BRD-K70511574_sunitinib_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K66577743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35144
BRD-K88573743_A443654_MDAMB231_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PAK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00959492
Childhood supratentorial ependymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.59352
ITPRIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00766913
SNU16	DepMap CRISPR Gene Dependency	1.0	3.78945
BRD-K58275986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00039
BRD-K80822897_NCGC00180994-01_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A52650764_Ingenol 3, 20-dibenzoate_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08590382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01103
ETV5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00923538
BRD-K81528515_nilotinib_MCF10A_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FBLN5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00449974
CIB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00788694
NDUFV2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061484
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4699
BRD-K53417444_OTSSP167_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SARM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.010082
VCAN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00460808
BRD-K90382497_GW-843682X_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KRT19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00805217
BRD-K23017938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40967
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0017
IL10RB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564731
BRD-K25737009_-666_PL21_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLA2G2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00715569
Mitochondrial fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
LRP12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00881225
MS4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00780614
Mineral absorption	KEGG Pathways 2026	1.0	null
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.46404
CTNNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00453882
BRD-A80960055_3203_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75311902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14558
ARPC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00629735
MDM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00689361
BRD-K08502430_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04153348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01738
BRD-K04210847_Tamoxifen, 4-Hydroxy-, (Z)-_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MPL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00492086
TGFB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00785563
ACTN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00723892
estradiol-373	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DDX39B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00727701
RAG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0142916
BRD-K37386363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05608
MINDY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0138366
BRD-A68797623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24507
BRD-K04853698_LDN-193189_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sirolimus-5932	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CYP2E1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00965229
BRD-K32010074_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626905
BIK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538143
GPR157	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620649
ZPBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00989131
BRD-K07303502_Arachidonyl trifluoro-methyl ketone_RMGI_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K90382497_-666_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
heart	GTEx Tissue Gene Expression Profiles	1.0	1.77747
PHACTR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00764757
intracellular monoatomic cation homeostasis	GO Biological Process Annotations 2025	1.0	null
NCIN87	DepMap CRISPR Gene Dependency	1.0	3.24144
KIF20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53773
MSI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00916509
BRD-K74148702_curcumin_EFO27_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00742478
SLAMF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00595663
POU2AF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.006246
BRD-K17482962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10344
PGF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00781987
CCL18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00794208
TMOD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00919683
LY-294002-1236	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Microspike	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
PMC9377669-tx1c00392_si_002.xlsx-TSA-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44100512_KIN001-043_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ETV4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00777516
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5088
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
BRD-A11678676_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EHHADH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0186643
BRD-K32526544_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DDX6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00929503
BRD-K33379087_tivantinib_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K17743125_S1085_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GPR17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647881
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.17497
PMC9377669-tx1c00392_si_002.xlsx-1160_PS-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
B4GALNT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608905
BRD-M86331534_BJM-ctd2-9_SW480_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	2.31189
ADAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571083
DPYD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579417
SERPINB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00805934
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7102
ALDH1A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517229
PMC9377669-tx1c00392_si_002.xlsx-DPH-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76401790_JNK-IN-5A_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD2AP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693312
BRD-K40329609_NCGC00184830-01_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hydrocortisone_homo sapiens_keloid scar_gds3071	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A77467113_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLFN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98406
BRD-K32744045_tetraethylthiuram disulfide_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TNFRSF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00726596
BRD-A25687296_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SYT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00792064
BRD-A84174393_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6145927-41467_2018_5729_MOESM6_ESM.xlsx-Chromatin_Modifier_Genesets-SCIBETTA_KDM5B_TARGETS_DN_KDM5B	Rummagene Transcription Factor Associations 2026	1.0	null
RGS12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00878436
BRD-K82374143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06195
BRD-K33379087_tivantinib_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.844984
ERP27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00717223
BRD-K35960502_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K01877528_TL_HRAS26_NCIH2073_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DLG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530974
BRD-K88573743_A443654_SKBR3_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K52339692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10955
NEK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00454096
BRD-K43620258_3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide_TYKNU_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05139
BRD-K49456190_PRIMA-1 MET_NCIH1694_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chlorhexidine-1525	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.04163
BRD-A19500257_geldanamycin_MDAMB231_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TMBIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00886149
ACHN	BioGPS Cell Line Gene Expression Profiles	1.0	0.899577
BRD-K71345532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00794
WDR6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00904753
BRD-K47658117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10948
BRD-K69840642_HDAC6 inhibitor ISOX_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
colchicine-630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NIBAN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00539832
intracellular zinc ion homeostasis	GO Biological Process Annotations 2025	1.0	null
BRD-A84327315_71820_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
estradiol_homo sapiens_gpl96_gse1045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99545815_PF-562271_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TRDMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576662
BRD-K60507178_Podophyllotoxin_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADCY2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00800447
BRD-K92636280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32444
BRD-K73768826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02838
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0877
BRD-K05402890_NCGC00165289-01_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K34968258_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K01976263_Emetine Dihydrochloride Hydrate (74)_HCC15_6.0_h_0.63_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K79779816_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K60219430_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04853698_-666_CL34_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00675268
BRD-K41895714_AS605240_MDST8_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLF10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00636245
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1754
PPP1R14B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00667361
NLRP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523791
BRD-A31107743_89671_A549_24.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0995
BRD-K17743125_S1085_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A60414806_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2925
BRD-K76202128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43685
BRD-K26689527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87156
naphazoline-1886	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K42964952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01297
BRD-K53792571_Inhibitor BEC hydrochloride_EFO27_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A24054354_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23478508_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K79131256_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLEC5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00875063
GIMAP8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00733833
CTSG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00590521
CHD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00619924
CD3G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00667416
BRD-K32439647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47712
LAIR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00578046
BRD-K42191735_buparlisib_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16478
BRD-K54839019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90845
ADAM30	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00644538
CLEC1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00974898
ATG9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35346
BRD-K48722258_Dilazep dihydrochloride_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ANTXR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00782277
doxylamine-1893	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PIK3CA_activemutant_56_GSE17785	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.16156
BRD-K02708799_GSK-1059615_BT20_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YDJC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00700209
AOC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00712084
ZBTB38	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00769151
trifluoperazine-4448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
talampicillin-2954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-U24835547_GSK1059615_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
copper sulfate-500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.013061
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.30149
TMEM60	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00748645
LCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00505371
BRD-U60236422_WH-4-025_SKBR3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NME1-NME2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00423256
COMMD7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00868406
BRD-K28296557_Akt inhibitor IV_THP1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K00892322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04688
MUC20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509249
BRD-K04546108_JAK3 Inhibitor VI_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K04623885_BIBR1532_RMGI_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATP5F1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00827557
BRD-U74615290_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VSIG10L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0051994
BRD-K69840642_HDAC6 inhibitor ISOX_RKO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K79239947_PF 573228_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SYNM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00707645
molecular_function	GO Molecular Function Annotations 2015	1.0	null
496100400_PCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.58608
paclitaxel_homo sapiens_gpl570_gse11550	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A39996500_radicicol_MCF10A_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TREML2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00846354
ciclopirox-2456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K98876398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80312
BRD-K52075715_Oxibendazol_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STYK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0082449
BRD-K72414522_AZD-5438_MDAMB231_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LMTK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00875068
tanespimycin-1006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-U60236422_WH-4-025_SKBR3_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GAS2L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533698
HOMER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00401238
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8381
ACLY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00637753
thiamphenicol-1704	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K68065987_MK-2206_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TLR9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00566959
IL13RA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555017
CCDC88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52977
BRD-K70511574_sunitinib_PC3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.54338
BRD-K77908580_entinostat_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOLH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00721896
CDC7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00903176
BRD-K19220233_JNK-9L_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00866496
ADAM15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.011647
FJX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00500044
GPR146	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608617
kaempferol-3579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K01649396_indatraline_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K33425534_exemestane_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
response to copper ion	GO Biological Process Annotations 2025	1.0	null
BMP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00855133
BRD-A24396574_celastrol_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NEURL1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0115307
astemizole-6807	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TET1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471099
TNFRSF19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00699669
disulfiram-1369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0062074
metoclopramide-3625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MBD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0115761
BRD-K13390322_AT-7519_MCF10A_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02050740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64921
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.96
BRD-K91145395_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IL12RB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564374
DXO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0082749
mt2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.685
BRD-K55187425_ON-01910_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHRNB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053256
CYP4V2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00928979
ZNF367	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00729128
GPR183	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556513
response to zinc ion	GO Biological Process Annotations 2025	1.0	null
BRD-K33882852_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00548869
BRD-K42918627_GSK-2126458_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NHEJ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0126566
SBK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00902428
CDK12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0089414
ALMS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00895602
EML4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566613
BRD-K81418486_vorinostat_RKO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDE3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00637109
BRD-K68336408_Tyrphostin AG 1478_AGS_6.0_h_56.78_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CNKSR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00758212
RELL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584804
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1937
BRD-K17743125_belinostat_HT29_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0232
SLCO4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00581681
BRD-A42031983_VU0415555-1_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ASNS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00364968
CYCS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0101737
BRD-K15825608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25007
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.803
BRD-K27737647_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ADPGK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049338
BRD-K68548958_-666_A549_24.0_h_20.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TC71	DepMap CRISPR Gene Dependency	1.0	2.74218
SMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00977647
suloctidil-5021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ALOX12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0139773
erythromycin-1928	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18255
CD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0114753
BRD-K63892915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44378
alexidine-3699	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81528515_nilotinib_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bergapten	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07844
BRD-A81541225_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ETS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479566
IFI16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00652064
BRD-K32821942_azathioprine_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	2.59017
BRD-K20655524_MEFEXAMIDE_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K67075780_TGX-115_HEPG2_6.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04613
BRD-K65945126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15374
BRD-K69932463_AZD8055_WSUDLCL2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K88378636_withaferin-a_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A02180903_BETAMETHASONE_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tetraethylenepentamine-412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K40175214_torin-1_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
butyl hydroxybenzoate-6446	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trifluoperazine-910	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K61776140_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A25337146_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rosiglitazone_homo sapiens_gpl96_gse7035	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
miconazole-1896	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K53992608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07385
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.20208
BRD-K38061943_NCGC00188488-01_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K67578145_GDC-0879_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CPT1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00388463
MPV17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00896076
BRD-K34581968_BMS-536924_HEPG2_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K43389698_BMS-387032_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04833372_GSK-1904529A_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92241597_CHR 2797_HEPG2_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K62418408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18484
CENPE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630495
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6364
10-methoxyharmalan-1743	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08558441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33327
GLRA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0153913
C4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554583
BRD-K38218737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23607
fluphenazine-1075	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659378
H6PD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605594
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04853698_LDN-193189_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A55416093_COLFORSIN_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.2658
BRD-K15108141_Gemcitabine_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
metampicillin-1440	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ASAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0104076
CDK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498533
BRD-K11663430_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRSS8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507652
BRD-K09842906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00931
BRD-A42628519_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TREML1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00849345
BRD-K49328571_dasatinib_HA1E_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KCNB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00739494
doxylamine-1973	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K71493640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39293
BRD-K04513994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95288
LRAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00804094
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.843022
TRPC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530804
CH25H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00597359
LEF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498589
BRD-K43375231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03287
ENPP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00755287
BRD-K26669427_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MXRA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0063441
SST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00708009
BRD-K47498351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01943
HLA-DPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00774972
BRD-K42191735_buparlisib_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81372870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.721
AG-013608-5949	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A71816415_PRAVASTATIN SODIUM_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K52075715_OXIBENDAZOLE_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
C8orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35718
BRD-K63068307_ZSTK-474_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K11129031_GEMFIBROZIL_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CDC25C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603451
BRD-A64977602_mirtazapine_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
suloctidil-2651	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BTNL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628144
BRD-K82036761_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TTC549	DepMap CRISPR Gene Dependency	1.0	4.02836
TREX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0117208
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0569
HEPACAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00716559
BRD-K70771662_11K-629S_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A80213327_NSC 23766_COV644_6.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXD4L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00444727
TOB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616476
TMEM52B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00538462
BRD-K23363278_CYT997_HCC515_6.0_h_1.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6557
BRD-K78867378_mw-A1-12_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC12A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00952715
PARP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00385531
IL4I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00665682
apigenin-1321	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BCAT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0107195
BRD-A45498368_WYE-125132_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A93975555_NCGC00167107-01_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SEMA6C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573036
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.249578
BRD-A28970875_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COPG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00967707
GPN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541037
dexamethasone-1396	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K78599730_manumycin A_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
midecamycin-1943	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
EPHA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00768918
BRD-A75172220_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K95037415_NCGC00167094-01_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
anisomycin-6764	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A75409952_wortmannin_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IGFBP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00833634
bladder	GTEx Tissue Gene Expression Profiles	-1.0	-1.17497
TSC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475703
BRD-K73290515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22013
TGFB1I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00795089
mestranol-4792	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SRRT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.011711
BRD-K67591072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07346
BRD-K69840642_HDAC6 inhibitor ISOX_RMGI_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mefloquine-6205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K05402890_NCGC00165289-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K17743125_belinostat_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A55484088_BNTX maleate_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CLIC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0106642
FMNL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00978841
IGSF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0117166
BRD-K21680192_mitoxantrone_SKBR3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K18861610_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EIF2AK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0103305
BRD-K80094086_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K47869605_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHRNA10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582364
UBTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79492
MFSD13A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00808046
GSTM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00824986
PFDN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0081224
USP18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102483
SET	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0112131
BRD-K92428232_GSK-461364_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00702032
azathioprine-2028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K44978960_NCGC00010428-03_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ANP32E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00482304
BTN3A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00877879
MAGT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517986
BRD-K81418486_vorinostat_A673_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCN10A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657318
BRD-A22783572_-666_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A42737819_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDKN2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0120425
BRD-K01351858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26104
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2876
BRD-K93716900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36013
methapyrilene-4990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K94144010_(-)-cotinine_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99749624_linifanib_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PODXL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00789377
XPO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.013385
ADD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0116715
YLPM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0107898
BRD-K86574132_-666_A549_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
estradiol_homo sapiens_gpl96_gse2251	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SLAMF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00783837
BRD-K67626097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38245
HDAC8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0101737
FMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549712
NOX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0102203
BRD-K74402642_Chemistry 2804_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KIF11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00834307
P2RY12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00801942
TGM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061849
BRD-K06666320_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97979
sulindac sulfide-308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81418486_vorinostat_HCC515_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD300E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00489988
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0052
PMC9377669-tx1c00392_si_002.xlsx-5_5-Diphenylhydantoin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52850071_JAK3 Inhibitor II_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K30677119_PP-30_HEPG2_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K26180392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04602
EHBP1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00705971
BRD-K12184916_NVP-BEZ235_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
zinc acetate_homo sapiens_gpl570_gds1617	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.30926
BRD-K22503835_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADAM19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0170275
BRD-K44100512_KIN001-043_LNCAP_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K47983010_BX-795_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MC4R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0148186
nucleus	GO Cellular Component Annotations 2025	1.0	null
BRD-K12502280_TG101348_NCIH508_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.16049
3T3-Swiss albino cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
GFER	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00818884
KLRG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00718224
PMC10322668-Table_7.xlsx-DE_genes_at_early_infection-List_of_de-regulated_genes_at_early_interaction_time_point_of_Dm28c_T_cruzi_THP1_infected_cells_From_Libisch_2020_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
TAF5L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0161014
BRD-K38340366_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATP2A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00414189
BRD-K28296557_Akt inhibitor IV_TYKNU_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IGFBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515599
BRD-K74302837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36541
G6PC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00780269
KHDC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00936042
BANK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0103487
ANKRD55	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00835118
BRD-A75409952_wortmannin_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07276
BRD-K15592317_CP466722_SKBR3_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LGR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00901418
SLC39A11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00927154
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
geldanamycin-6187	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rosiglitazone_homo sapiens_gpl96_gds2705	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FASN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00424114
GJC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00758322
BRD-K54790089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71008
CPNE3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00309508
BRD-K15108141_gemcitabine_VCAP_6.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K89014967_S1475_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K86003836_flubendazole_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94580036_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ROCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0114635
BRD-K10882151_BO2 (inhibits RAD51)_HT115_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72717
BRD-K31342827_GF-109203X_SNUC4_6.0_h_12.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28296557_Akt inhibitor IV_NCIH2073_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
S100A13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00420869
ADARB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00719922
BRD-K88677950_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K50191826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26251
BRD-K17140735_-666_AGS_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chlorzoxazone-1416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3624
PTPRM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00700641
CDKN1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0100509
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00657209
BRD-K99252563_QL-XII-47_MCF7_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
zinc acetate_homo sapiens_gds1617	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30306
DOHH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0130233
EEF2K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00728875
BRD-K01669916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.334
KCNA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00682031
LY-294002-4460	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K43389698_BMS-387032_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04887706_AKT-inhibitor-1-2_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
KCNG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00848332
BRD-M86331534_BJM-ctd2-9_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28360340_TW 37_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
B2M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048655
BRD-K62492257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52681
ACTR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00347153
FAM200B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00857465
SLC9A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00427005
BRD-A19500257_geldanamycin_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
INSRR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623615
PFKFB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00717813
BRD-K64890080_BI 2536_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K80672993_Compound 58_HEPG2_6.0_h_88.8_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55611
BRD-K21680192_mitoxantrone_MCF10A_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HRH4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0110472
CYBB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00874098
cicloheximide-6220	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55465787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57272
BAG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531232
flucloxacillin-6507	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
megestrol-3091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
clioquinol-3084	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
CSDC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511204
RNF123	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00987025
BRD-K64730761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15637
CAMK1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00647469
exemestane-165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GANC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0100789
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9491
fulvestrant-367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49075727_nintedanib_HS578T_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EGR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0069014
BRD-K68202742_trichostatin A_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99749624_S1003_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dirithromycin-1712	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CD226	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00628377
BRD-K02708799_GSK-1059615_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NTPCR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00840316
BRD-K44100512_KIN001-043_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K11853856_PJ 34 hydrochloride_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC19A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00868077
BRD-K19540840_saracatinib_LNCAP_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
APRT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00508854
BRD-K74402642_Chemistry 2804_OV7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22108
ambroxol-6719	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K28296557_Akt inhibitor IV_RMUGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PIK3R6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00720184
BRD-K35004659_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCLS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00729602
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3452
BRD-K97764662_PD-173074_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
xylometazoline-7020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MLLT11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00715891
KCNQ2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00614152
BRD-K76703230_YM-155_A673_6.0_h_0.31_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CARMIL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00736626
QRICH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0125984
SHC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00701116
KIR2DS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0124015
MEF2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00500933
BRD-K64857848_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NUCKS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00404356
BRD-K24132293_piperlongumine (HPLC)_JHUEM2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0075859
ELF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00963453
BRD-K45712538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19998
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0139
BRD-K88573743_A443654_PC3_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A19037878_trichostatin A_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55191674_PENICILLIN G POTASSIUM_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
etynodiol-3102	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PHGDH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00485386
BRD-A22783572_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100664_HIP_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.35496
BRD-K97309399_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86631041_MLS-0435556.0001_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	2.09574
FBLIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00809574
BRD-K92579151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09969
LSP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0127895
BRD-K82379643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09777
BRD-K75081836_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2957
PMC9377669-tx1c00392_si_002.xlsx-Ampicilin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
NNT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00287465
STK36	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00576645
AMIGO3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0081581
naltriben-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19667
ODF3L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0131068
BRD-K40175214_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TAF1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00771576
BRD-K85493820_KM 00927_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CYP21A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0122784
MMAA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00551085
PRKAB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00444047
phenoxybenzamine-4652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16485616_mocetinostat_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
esculetin-6499	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K42436189_AZ20_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TTC38	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0107305
DNAJB9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062202
TP53INP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00725346
BRD-K01237500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36095
BRD-K91623615_ABT-751_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6099
BRD-K12184916_NVP-BEZ235_BT20_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K89692698_-666_A549_6.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K82216340_medroxyprogesterone 17-acetate_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23363278_CYT997_PC3_24.0_h_1.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K32223081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57381
BRD-K21680192_mitoxantrone_MCF10A_3_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K80348542_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
methotrexate_homo sapiens_gpl570_gse11440	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PGK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066008
BRD-K06765193_(E)-2-(1H-Benzoimidazol-2-yl)-3-(5-nitro-furan-2-yl)-acrylonitrile BRD-K06765193_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Atrovastatin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09271653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66315
BRD-K77051246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05755
verteporfin-3556	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K74148702_curcumin_U937_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTSF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00669231
BRD-K02014458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06505
BRD-K92428232_GSK-461364_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0104304
BRD-A19037878_trichostatin A_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	1.0	0.829118
BRD-A45889380_QUINACRINE HYDROCHLORIDE_SW948_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11732233-mmc1.pdf-40-HOXB5_HOXB5	Rummagene Transcription Factor Associations 2026	1.0	null
Alveoli adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
TUBB4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0105811
BRD-K81418486_vorinostat_SW620_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K15791587_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K87909389_alvocidib_MCF10A_3_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BBOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00427793
CYP1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00634341
SAA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00829198
AMIGO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00829577
CBX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00460033
CNTN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0119833
DKK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00753805
BRD-K13646706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37883
BRD-K60587793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19066
BRD-K34581968_BMS-536924_RMGI_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75081836_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
suloctidil-6675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02637547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24753
LGALS9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501175
ZNF276	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00652568
IL12RB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00753146
ARID2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063589
PPID	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00705407
BRD-K99545815_HY-10459_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
albendazole-1547	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WM2664	DepMap CRISPR Gene Dependency	1.0	3.03056
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.633
thapsigargin-7053	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A45498368_HY-10044_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RHOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19432
ZNF781	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87941
SYK_knockdown_189_GSE54065	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.63514
BRD-K05464208_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPIP5K1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00842008
IGSF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00642633
IL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00699298
BRD-K47203692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2393
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49228
XRCC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00401754
BRD-K68143200_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
estradiol-1021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K79090631_CGP-60474_MCF10A_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCL8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509115
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62201
BRD-K40758391_cjd-pla-49-3_NCIH1694_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K53972329_CT-INCB_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PANX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633692
BRD-K64800655_PHA-793887_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SG231	DepMap CRISPR Gene Dependency	1.0	2.25351
phenoxybenzamine-5613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A35869383_ibrutinib_HCC515_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K40175214_torin-1_MCF7_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A62184259_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100571_FWM_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8119
AKR1B10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00648986
PAOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00710799
ALDH1B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479513
metixene-5018	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BMF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00689185
496100641_PCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22942
ITM2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00831944
BRD-K68174511_torin-2_SKBR3_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLEC4G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00842381
LGALS16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00738906
TC32	DepMap CRISPR Gene Dependency	1.0	2.08475
BRD-K06926592_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A79768653_sirolimus_A549_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mometasone-5116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TNP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542099
ERG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628143
OGA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517134
BRD-K63864310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81564
CEACAM7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00614294
BRD-K76166595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13719
BRD-K58214070_N-{3-[(2-Chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K96076993_-666_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DUSP16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00712262
RNF24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0104393
ADGRE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00635519
BRD-A75558199_NCGC00238537-02_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.435981
AMPD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00589644
5109870-904	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PKD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00912527
DPP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00646489
KRT23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00850126
BRD-K09131889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3219
PBXIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483661
SLC47A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00543477
ATP2B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00505094
BRD-K32292990_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K60287661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02755
SERPINF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00711755
SSTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00648427
CHPF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00808156
TNIP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0134704
TRAF6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00833781
FCGR2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00665627
GNRHR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00792899
BRD-K64890080_BI-2536_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A34806832_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81418486_vorinostat_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99252563_QL-XII-47_LNCAP_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00754962
ME1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055923
KMT5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586266
BRD-K65331431_BL-010_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
ECSCR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00965929
TTC39A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00707633
BRD-K92317137_-666_MDST8_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37986
BRD-A02481876_Importazole_NCIH2073_6.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSTA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0130713
BRD-K21680192_mitoxantrone_SKBR3_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NSD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622316
hexetidine-3318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16189898_CHIR-99021_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K92317137_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70977695_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K31852848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23883
BRD-K02708799_GSK-1059615_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DAGLA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00747488
CD3E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0137282
LM-1685-612	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K62459624_T5212475_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20696416_NVP-AEW541_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K35667841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18419
perphenazine-2040	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LRRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552339
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41768
BRD-K21680192_mitoxantrone_SKBR3_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
INHBC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00886494
BRD-K81418486_vorinostat_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02356765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67282
TOP2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541285
BRD-A16311756_ETHOPROPAZINE HYDROCHLORIDE_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FAM110D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96818
BRD-K89997465_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CXCL12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00382134
BRD-K01615696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04525
AURKC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00784598
methylbenzethonium chloride-6045	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NHP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0117409
BRD-K66032149_VU0365117-1_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ERN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00665004
BRD-K05804044_AZ-628_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1419	DepMap CRISPR Gene Dependency	1.0	2.12601
CD163	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00631824
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0295
BRD-K92428232_GSK-461364_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K90826279_-666_MCF7_24.0_h_20.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FLT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00981577
BRD-K34363599_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K03371288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46146
CCDC51	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00804599
BRD-K81418486_vorinostat_RMGI_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADCY7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623016
PRSS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00746586
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4957
proguanil-2944	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pyrimethamine-1894	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K16533489_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0069657
TMC8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610324
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04311
BRD-K64800655_PHA-793887_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SDF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658971
UBE2F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737826
BRD-K68512873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34555
DYNLRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00672776
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44295
DNLZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628513
GPX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00787083
RARA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00864654
SYNPO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00775576
PRKG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00757036
TRHR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00633566
PNPLA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48006
BRD-K01976263_Emetine Dihydrochloride Hydrate (74)_MCF7_6.0_h_0.63_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6124
SEC23IP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00529439
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9453
MYC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00473597
PMC9377669-tx1c00392_si_002.xlsx-Methorexate-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
wortmannin-506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TUBA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00724398
BRD-K92428232_GSK-461364_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CENPU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0092141
SLC18A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642174
BRD-K04853698_-666_SNU1040_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
5182598-868	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8519
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NR1I2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530785
JAG1_OE_GDS3571_40_human_endometrial stromal cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
fluticasone-2928	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHI3L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00764162
NTRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00615379
BRD-K56563758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33091
IL1RL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677813
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90323
dipyridamole-2017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K17743125_belinostat_PC3_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HSPA1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00822733
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	0.838834
MMACHC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564495
GSDMB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0107226
FADD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0097113
BRD-K12867552_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAB33A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0113673
BRD-K54506283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71881
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.759575
KCNQ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0042568
BRD-K20285085_R406_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STAMBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00577658
BRD-K44100512_KIN001-043_MCF10A_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZMAT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00933005
LY-294002-4451	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A19633847_PERHEXILINE MALEATE_HT115_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A45498368_WYE-125132_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAMKK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00717978
BRD-K97784715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25411
BRD-K92571446_WZ-3105_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
95T1000	DepMap CRISPR Gene Dependency	1.0	3.21947
BRD-K06863452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29907
betulinic acid-1345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K17743125_belinostat_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K87964538_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RPS6KA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00470621
NEUROD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706507
CHRNA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00617626
TOMM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608103
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9022
SEL1L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00753557
BRD-K11258147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02917
BRD-K67868012_PI-103_MCF10A_3_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
imipenem-1724	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RUNX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572971
BRD-A41451487_PK-11195_SW620_6.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00714824
BRD-K78167523_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K77554836_Triamcinolone_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAGI3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00918404
BRD-K64890080_BI-2536_LNCAP_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49328571_dasatinib_A549_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARAF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609444
etamivan-7021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Levothyrox-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49371609_528116.cdx_VCAP_6.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K81418486_vorinostat_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE236502_1_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K00824317_Flurandrenolide_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TACR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509805
BRD-K34170797_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TTK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00443979
Metallothionein domain, vertebrate	InterPro Predicted Protein Domain Annotations	1.0	null
VTCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00773615
probucol-1608	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K99221119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38525
SPTLC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00538336
BRD-A16820783_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TMPRSS9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00813196
nifurtimox-6608	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TIMD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539558
ARF6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00949626
CLEC12B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00676884
BRD-A19037878_trichostatin A_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92317137_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K69159985_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K51443908_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498011
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2476
PANX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00867193
ORAI3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0111798
BRD-A69648159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12663
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4793
CRTC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00678173
CEP72	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00861184
KCNK15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.004893
BRD-K61978712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57805
BRD-K67868012_PI-103_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23673040_(Naphthalen-1-ylamino)-acetic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
labetalol-1550	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDK9_knockdown_71_GSE21751	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.22441
BRD-K74486276_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04853698_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23478508_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCRL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00692544
APBB1IP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601497
GPR87	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00576492
BRD-A71390734_4-Demethoxydaunorubicin hydrochloride (65)_AGS_6.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC47A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694987
BMX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00724086
EPHB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00352892
HCST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00870634
INSM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00983839
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2289
BRD-K50201262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21843
DNAAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00563116
DAZL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00688058
copper sulfate-575	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70511574_sunitinib_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K64052750_gefitinib_BT20_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K56301217_ABT-737_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LY-294002-1074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
halofantrine-6509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HUNK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00743289
BRD-K63675182_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cellular response to zinc ion	GO Biological Process Annotations 2025	1.0	null
STAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0079137
BRD-K43050752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34579
WRAP53	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_SKM1_6.0_h_6.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
betulinic acid-3281	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94012289_OSI-027_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fulvestrant-310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92723993_imatinib_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K30707190_PNU 74654_H1299_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55127335_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.41008
BRD-K28034484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9822
BRD-U51024685_HG-6-64-01_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
edrophonium chloride-1936	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K74305673_IMD 0354_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A19500257_geldanamycin_HME1_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K11158509_TYRPHOSTIN B44 (-)_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO205	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.31815
BRD-K63770300_NCGC00188740-01_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HUO9	DepMap CRISPR Gene Dependency	1.0	3.39466
LRP8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0102446
PRKCD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00370792
BRD-K83963101_MLN-8054_PC3_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K44652223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68964
CDIPT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00798746
PMC9377669-tx1c00392_si_002.xlsx-Valproic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12184916_NVP-BEZ235_MDAMB231_3_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02708799_GSK-1059615_SKBR3_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
cation binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K72703948_ZM-447439_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBPMS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00612818
BRD-A80641450_FR 139317_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8739
WIPF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664911
monastrol-311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99582188_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHCHD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626804
ISG15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00822568
ENTREP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00631462
BRD-A25687296_EMETINE_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42918627_GSK-2126458_LNCAP_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K03849840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26671
BRD-K67123444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45968
BRD-K21520694_Sulfacetamide sodic hydrate_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95741
BRD-A18328003_GDC-0980_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pirinixic acid-495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K20942146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25732
EXTL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00782542
SPHK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00802258
IFI6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0051056
PREX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00817877
BRD-K30849099_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SDCCAG8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00759034
DLG5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0164077
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8632
Metallothionein superfamily, eukaryotic	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-A76490030_2-[(chloroacetyl)(3,4-dimethylphenyl)amino]-N-cyclohexyl-2-pyridin-3-ylacetamide_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A39996500_radicicol_MCF10A_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K91290917_Amodiaquin dihydrochloride dihydrate_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PTGIS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00679469
RASGRP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00725704
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3059
FHL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00701242
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2505
estradiol_homo sapiens_gpl570_gse5102	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K44100512_KIN001-043_MDAMB231_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K29113274_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HORMAD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0123911
clioquinol-6461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
FHAD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0070722
BRD-A18328003_GDC-0980_BT20_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HSPA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628741
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90451
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.88874
BRD-K54956860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77673
BRD-K36740062_GSK-1070916_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COX6B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00866406
DVL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0036203
Bardet-Biedl syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.926
BRD-K20696416_NVP-AEW541_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K64890080_BI 2536_A673_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SEMA4G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00947344
BRD-K70681322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42803
BRD-K78126613_MENADIONE_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRPS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675796
PTGIR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0111236
GRK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050373
BRD-A75409952_wortmannin_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TUBB2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0121129
BRD-K81644801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92528
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4759
BRD-K81418486_vorinostat_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MTA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0103855
BRD-K61323504_sb 225002_NCIH596_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K43620258_3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide_NCIH596_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59402582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00946
BRD-K83972459_JWE-035_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BEND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79365
levodopa-1892	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K06593056_-666_WSUDLCL2_6.0_h_20.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K32238524_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00486907
SLC26A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0106091
BRD-K35080107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13963
CFB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00629748
astemizole-2211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K21680192_mitoxantrone_MCF10A_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TNIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00939569
BRD-K56515112_6alpha-methyl-11beta-hydroxyprogesterone_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
desipramine-1596	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A75409952_wortmannin_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HLA-DRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00955609
BRD-K73397362_Purmorphamine_HT115_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CBR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00399587
BRD-K69840642_HDAC6 inhibitor ISOX_SNUC5_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC1A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00363477
vidarabine-3445	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RARG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066712
BRD-K14534138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44941
LN319	DepMap CRISPR Gene Dependency	1.0	3.86514
PLK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00925347
BRD-K51608872_N,N-dimethyl-6-({[1-(1-naphthyl)-1H-tetrazol-5-yl]thio}methyl)-1,3,5-triazine-2,4-diamine_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K95192796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67326
BRD-K64890080_BI 2536_THP1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AMY2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00644528