association	dataset	threshold value	standardized value
GSE190177_1_v_0_sgpl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13422
LYST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00491206
BRD-K93693615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54424
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9831
NUP88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01372
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188382_2_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42145213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13181
BRD-K73227539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04017
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56916066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37658
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSTA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00648432
PMC11076560-42003_2024_6230_MOESM5_ESM.pdf-42-ENSG00000164048_ZNF589	Rummagene Transcription Factor Associations 2026	1.0	null
APCDD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00849022
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHEK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00762245
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE196962_4_v_1_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZRANB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40791
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.812
CCK81	DepMap CRISPR Gene Dependency	1.0	4.99156
GSE128333_3_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
increased circulating phosphate level	MGI Mouse Phenotype Associations 2023	1.0	null
RPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23394
BRD-K82432417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.349
SKNMC_BONE	CCLE Cell Line Proteomics	1.0	2.99453
GINS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00430594
H2AC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461903
BRD-K32131036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40804
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
increased circulating creatinine level	IMPC Knockout Mouse Phenotypes	1.0	null
TIM22 mitochondrial import inner membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0094
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7409
BRD-K96641838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18781
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1984
C5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00367211
Mitochondrial membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74468
MUC20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00483996
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33075
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00491976
BRD-K05645536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30316
TAF6L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00670694
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.618
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEx AdiposeTissue 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-5.17818
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PRR5L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00791828
Mitochondrial envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ISLR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0065836
EML4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00381759
BRD-K28431799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20068
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2188
SW954	DepMap CRISPR Gene Dependency	1.0	2.1194
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K92431275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05668
CYP1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00644444
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1A_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09560946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1619
BRD-K84613654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02522
GSE48812_7_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_3_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00537646
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
EIF4E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00745233
TCF7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00687078
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
molybdenum ion binding	GO Molecular Function Annotations 2023	1.0	null
CD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00508847
ANKK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555233
GSE248874_1_v_0_pcdh9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K80469338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44555
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
mitochondrial outer membrane	GO Cellular Component Annotations 2023	1.0	null
BRD-K21420222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29721
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48691065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23566
Chylomicron	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.124
ENTPD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00638405
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2699
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFAND2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00474258
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
DPP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00492406
BRD-K36713925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25671
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K60076175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38139
YWHAE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38242
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56239
GSE178340_5_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IL2RB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00643962
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1B_HNF1B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_11_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSTA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00529774
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15291
BRD-K35469110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02533
NELL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0060492
Endopeptidase Clp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41774018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89094
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K93613839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30528
BRD-K11925125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19164
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34695
MM77	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33353
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.30025
CRCGN013_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0153
C6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00443613
BRD-K44722328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43768
BRD-K96845170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01373
RIPOR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00561067
BRD-A80010944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2574
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GABRA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00492881
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09872
DEFB4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00516263
BRD-K35326556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1242
BRD-K51153795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88669
DCLK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595469
UNG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00740582
CRCGN011_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.95825
BRD-A62995832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52307
Organelle outer membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K35828963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41113
NUP160	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0065033
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1143	DepMap CRISPR Gene Dependency	1.0	2.86772
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176305_0_v_1_rotenone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComUP-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70314
PMC5732738-oncotarget-08-103415-s002.xlsx-CAMA1_DEGs-Genes_differentially_expressed_by_1_25_fold_between_parental_CAMA1_cells_and_GATA3_mutant_knock-in_clone_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52552873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33661
BRD-K38571893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25274
PPIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16585
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6453
GSE155162,GSE155169_1_v_3_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
R3HDM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00944426
BRD-K86371068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25762
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1861
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.03185
CCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00451888
BRD-K53191200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2848
ATP1A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618127
BRD-K81619018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29652
GSE246567_0_v_1_acat2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83655
HEYA8_OVARY	CCLE Cell Line Proteomics	1.0	2.29239
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP-dependent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
P4HA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00348017
PARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12947
KCNJ12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536979
IGR1	DepMap CRISPR Gene Dependency	1.0	2.65777
SDSL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554033
LDL cholesterol levels in current drinkers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNMT3L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.004929
BRD-K80679698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15483
GSE190316,GSE190324_10_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34717
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.5885
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.43445
PMC5732738-oncotarget-08-103415-s002.xlsx-MFC-7_DEGs-Genes_with_significantly_different_expression_between_parental_MCF-7_and_GATA3_WT_clones_with_adjusted_P_value_0_05_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Jejunal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41282
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.96408
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K39624517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40793
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MORN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00621987
GPR17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00516355
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147626_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DCSTAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00710771
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48394
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139455_4_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79508
BRD-K39709957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60122
BRD-K42971210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35767
GSE161864,GSE161866_1_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15194
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08201
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A08363225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01906
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3876
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K88418404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1096
RELL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608938
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12356310-mmc1.xlsx-Rep_3_Control_and_MTR4_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08587
NOL4L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660391
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13269
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9038
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RT112	DepMap CRISPR Gene Dependency	1.0	2.74948
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20969
BRD-A57474391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01566
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169356_2_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32037893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27957
BRD-K80233876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3607
HCC1937	DepMap CRISPR Gene Dependency	1.0	4.0477
BRD-K85972696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2797
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04772
DOHH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639929
Cholesterol, total	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
HCC95	DepMap CRISPR Gene Dependency	1.0	2.0406
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_15_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A1BG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641587
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
levocabastine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39231
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.8279
OGT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0076359
BRD-K83190598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30638
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VSTM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00726231
BRD-K40189164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50756
GTEx Nerve 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-6.95258
BRD-K26395018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35884
BRD-K36237864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05534
KRTAP5-8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597219
ABCC8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00847545
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K89923892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23277
OLFM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00558039
PPIG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00481817
MDAMB157_BREAST	CCLE Cell Line Proteomics	1.0	2.54466
EHMT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00421318
UBE2E2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576464
GSE190384,GSE190386_6_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vaginal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
496100590_FWM_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27432
PMC12062214-41467_2025_59646_MOESM5_ESM.xlsx-HMGA2_activated_repressed-Ensembl_ID_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
HPN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596899
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35723
GSE115395_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_11_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF276	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00422346
BRD-K53354260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15458
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77144444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17708
PRKCE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522419
shikonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5407
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1175
BRD-K39396484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48815
BRD-K44421266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4661
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28674
cellular nitrogen compound biosynthetic process	GO Biological Process Annotations 2023	1.0	null
BRD-K34815008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05513
BRD-K81543095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67396
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K03697080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62979
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6718408-41467_2019_11884_MOESM9_ESM.xlsx-YAP1_RELA_DEGs_mice_human-Human_Gene_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	4.41319
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76677554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20302
BRD-K19662956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64236
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41185648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73997
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6056
PMC12500496-262_2025_4178_MOESM2_ESM.xlsx-THP1_enriched_for_CVGBM-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24166534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44257
BRD-K81217407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43254
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RRP15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00753387
CRCGN014_HEPG2_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19932
BRD-K96265882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69698
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60168
Biological oxidations	Reactome Pathways 2024	1.0	null
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K08817808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4617
ADAMTSL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511651
BRD-A02612852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11429
BRD-K43237307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44705
CNTN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00803873
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_10_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUGC3_STOMACH	CCLE Cell Line Proteomics	1.0	2.90446
BRD-K53050301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16398
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0449
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Estimated glomerular filtration rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
BRD-K36176133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1459
GSE258991_5_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3921
MTCH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618351
BRD-K58382884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34476
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GZMH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.006702
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20912596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19975
BRD-K30933750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06743
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE167474_2_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SH3BP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00304648
BRD-A64374397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72429
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34254821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1292
BRD-K87418665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03983
BRD-K76617730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36876
SLC7A9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049972
GSE146840,GSE146842_3_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0745
PMC5404927-elife-24463-supp1.xlsx-1b_ERM_proteome-Gene_names_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
nitric oxide metabolic process	GO Biological Process Annotations 2023	1.0	null
KMT2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509459
BRD-A67552019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09732
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8074
EGR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552808
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05029
Total cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
transition metal ion binding	GO Molecular Function Annotations 2025	1.0	null
levallorphan-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07991
BRD-K24108193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52211
HDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.9699
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09583
GSE229973_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13982
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.13464
SSTR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540838
BRD-K52225720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41622
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.445
GSE144484_0_v_3_mllt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_7_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98478
SRSF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00685738
BRD-K62965224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33978
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46137
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24811
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48019
NCKIPSD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00622159
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MMP28	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061003
KON	DepMap CRISPR Gene Dependency	1.0	3.1016
CRCGN012_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30262
BRD-K36778976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5768
PPP3R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06285
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33965
ACY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.004632
HS695T_SKIN	CCLE Cell Line Proteomics	1.0	2.83129
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4558493-cddis2015190x3.xlsx-SOX4-Unnamed_1_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COL1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00425729
DPF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507405
DAOY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
F-cell distribution in sickle cell anaemia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
oxoacid metabolic process	GO Biological Process Annotations 2025	1.0	null
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28552
TLR9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685199
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
FCGR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00475728
BRD-K33573676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7147
NR2C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523139
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4733
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.9
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LRRC75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25873
CT45A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00639867
GSE126776_2_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD247	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664283
SLC7A11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664064
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0814
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37033753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7134
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GADD45G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19537
nitric oxide biosynthetic process	GO Biological Process Annotations 2023	1.0	null
BRD-K17566112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02193
very-low-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.724
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K12431811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64509
BRD-K53293966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06617
ACSL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00974508
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.64573
CRCGN009_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22978
BRD-K27347421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51386
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26373865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75843
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K55877261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.809
BRD-K33702515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14489
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CD2AP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00512633
MDBK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nonalcoholic fatty liver disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
CRCGN009_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36495
Alanine aminotransferase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.90458
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87530935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28662
BRD-A91461229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23153
RPS6KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10359
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TACR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00567835
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	7.6696
BRD-K90094729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74399
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MPT synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.949
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FBXO22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00571205
UBASH3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0068433
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34521
NIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0051825
SPRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15506
THBD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00709645
TMEM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22102
BRD-K52157979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01891
BRD-K52101275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35983
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2108
Low density lipoprotein cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.25229
MZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10372
PMC5692555-pnas.1708341114.sd04.xlsx-3TFs_no_TFAP2C-gene_TFAP2C	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mitochondrial outer membrane translocase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.189
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25922
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAPKAPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00342494
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACAT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00354734
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSK3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556306
CRCGN013_HEPG2_24H:H21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00489
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4624
BRD-K35942122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41153
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K13888422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88555
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	117.595
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28117
BRD-K64632606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5927
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1346
EPN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0042492
CLTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84018
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01579
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07351191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00119
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intermediate-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54694941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16817
SORD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00746758
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PLA2G2E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00665102
BRD-K45717258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05503
BRD-K82562625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28902
Cirrhosis (multi-trait analysis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.3
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02209
BRD-K11013450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85708
GSE204811,GSE204813_1_v_3_trim29_human	RummaGEO Gene Perturbation Signatures	1.0	null
STKLD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00662181
BCL2A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00661383
CSF2RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671083
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.929
BRD-K76508844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35793
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mitochondrial outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.958
GSE115542_2_v_0_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K82774801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69216
NEIL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555031
BRD-K83463455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14773
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01947
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
HUH7	DepMap CRISPR Gene Dependency	1.0	2.6891
NELFE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00699342
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A14098586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24574
MCFD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706647
BRD-K13445266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20505
BRD-K00920341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18174
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134375_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.13518
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8635809-Table_2.xls-LPS-downregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FGG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601417
VCAN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00434662
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40621788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04156
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HAPLN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049757
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6589
JPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11291
BRD-K46607226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30476
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16823
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11799275-Table1.docx-5-GLI1_GLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.58088
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nitrate metabolic process	GO Biological Process Annotations 2023	1.0	null
TR146	DepMap CRISPR Gene Dependency	1.0	2.14513
CERS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00589156
Umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PICALM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590299
GLUL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00731641
SDC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694114
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12205
DEDD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703433
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Triglyceride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.7
TE5	DepMap CRISPR Gene Dependency	1.0	6.76397
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HNMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00799114
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07242
BRD-K92312193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06497
GSE57871_6_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5604
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60247
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18558473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43365
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10244410-41467_2023_39054_MOESM5_ESM.xlsx-PIE-LIN28B-GeneSymbol_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.517
BRD-K81728234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13009
GSE234289_3_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
MXRA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00695765
SNX10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630207
BRD-K52123365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07194
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64736
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0556
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30776
CD40LG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00506343
TEC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00448252
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0403
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
HIP1R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00516839
TAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00427609
GSE130676_0_v_1_suds3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67991
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0058
BRD-K48699175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35321
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04465
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Apolipoprotein A1 levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.13979
BRD-A27422067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12359
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
INTS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45339
BRD-K89000385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04274
ITGA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555781
BRD-K21544408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19275
BRD-K25736729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72462
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.575
PMC11143964-jciinsight-9-161356-s009.pdf-17-TBX2-AS1_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35347834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54649
MTNR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467439
BRD-K71761800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06555
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:J20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03705
ID2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00382104
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00456869
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186460_0_v_2_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158632_2_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K22748970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12174
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
PDS5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047265
MBNL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622101
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24386
chr1_220695166_A_G_b38	GTEx eQTL 2025	1.0	1.32701
LSP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483869
BRD-K93601851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19804
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134375_4_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle outer membrane	GO Cellular Component Annotations 2023	1.0	null
SLA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00421077
SPATS2L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00624647
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6286
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29264
BRD-K47582411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86634
ATP23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597842
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAK-285	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
HNRNPCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53508
AXIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00433071
MAP3K9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00598673
CRCGN016_MCF10A.WT.HP_24H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00167
PMC6591464-Table_4.xlsx-Sheet_1-Non-AIRE_regulated_genes_random_set_3_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
KYAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471142
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85473
GSE196117_6_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRYZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00415539
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07761
BRD-K03549232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30984
GSE218727_0_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
increased spleen weight	MGI Mouse Phenotype Associations 2023	1.0	null
OVTOKO	DepMap CRISPR Gene Dependency	1.0	2.96427
HDAC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00466898
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9714
GSE165307_2_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5227
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K27398402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10974
COX5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054162
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	8.02325
ELOF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059235
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K11404512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2847
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Monocyte early outgrowth colony forming units	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
PIK3CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00745078
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K04710685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02271
GSE137702_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51439
ANGEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11644
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.80387
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.71805
CMPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549971
BRD-K74755318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27153
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	3.59505
NLRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061169
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4817
mitochondrial membrane	GO Cellular Component Annotations 2023	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7906
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nitrate metabolic process	GO Biological Process Annotations 2025	1.0	null
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K51666223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92371
BRD-K74843557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50348
BRD-K12340493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19707
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.09605
GPR132	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00505475
NDUFS7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503888
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.517
Organelle outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.952
BRD-K45361857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16905
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19511
Cecal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.493
GSE199204,GSE211619_4_v_5_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178340_5_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ejg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
Outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.891
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-421_ChIP-Seq_H3K9me1_2_AR_differential_expression_upon_KDM3A_or_AR_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76908
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37737
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23664
GSE196962_2_v_3_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72369
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CYP21A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00531418
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K78082598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0787
BRD-K69699301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61324
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4196
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.82362
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
chr1_220797706_G_T_b38	GTEx eQTL 2025	1.0	1.70611
NUGGC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599697
SCAMP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00436088
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0424
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32485
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45177
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K92195351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12355
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.63515
TSPO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00650787
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00951
ZNF829	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05378
CRCGN009_HEPG2_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27562
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.666
BRD-K31034311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69115
TMEM131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80972
BRD-A46778020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13206
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8727
RAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471041
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K30727702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06764
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HslUV protease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
BRD-K51411441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05819
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.12218
DNAJB9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0100749
BRD-K47762331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20182
BRD-K38538662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98493
BRD-K34798837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55919
ENPP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518772
CRCGN017_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12935
SIGLEC8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00842558
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08895
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03638
CRCGN016_MCF10A.WT.HP_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60666
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17781
PRDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0106
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_2_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KOC-7C cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.238
TACSTD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00713158
BRD-K34974135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89907
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRD5A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00625019
BRD-K42899345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05677
BATF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00539515
Gubernaculum testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.667
CRCGN015_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69569
BRD-K37213205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09678
BRD-K81956993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64754
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
increased blood urea nitrogen level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE188721_3_v_1_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.577
UPCISCC152	DepMap CRISPR Gene Dependency	1.0	3.67368
BAX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00491695
transition metal ion binding	GO Molecular Function Annotations 2023	1.0	null
BRD-K25868508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02106
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K42789863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26213
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ractopamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48468
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CYP2S1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598549
BRD-K38380337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09902
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
DARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622053
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04537
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_1_BioID_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12035825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64382
GSE241108_1_v_0_sulfasalazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37830990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39245
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19461
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41528
BRD-K41562445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63451
Oxidoreductase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC11694450-Table_1.xlsx-MR_to_MM_at_2_DPI-Supplementary_Table_1_1_Differentially_expressed_genes_in_the_cecal_tonsil_transcriptome_in_the_M_R_group_compared_to_the_M_M_group_at_2_DPI_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A80705936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54859
GSE162015_2_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75679095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08841
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE209698_2_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47366416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49611
BRD-A01403444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3776
AP2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39062
GSE48812_8_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP3_cds_exp_down-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173307,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	1.0	null
nitric-oxide synthase complex	GO Cellular Component Annotations 2025	1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RHPN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541697
BRD-K92172862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02959
BRD-K93032100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14563
SLC13A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00751383
BRD-K13873561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69694
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85633971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64179
BRD-K53548389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74662
BRD-K53291208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88011
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183113_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83898
PANK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00489497
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GLOD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02279
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17524
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K41133627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77656
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72501
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
APOLD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00805887
CHRM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00705523
BRD-K43287163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24486
POR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00774879
PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92433763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18826
BRD-K31503053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64391
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63194
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CLCF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00521739
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K92311828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0384
SYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35368
HEL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	15.5037
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
MIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4065
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.41549
BRD-K81647747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57582
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52566
NUDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65359
GSE185519_6_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE94849_6_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PKM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00657896
BRD-A27844016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67975
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A17687311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03553
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.62357
BRD-K82784817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3596
GSE143662_3_v_1_dcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.21436
triglyceride-rich plasma lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.717
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.87097
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75446
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ICC10	DepMap CRISPR Gene Dependency	1.0	2.47283
BRD-K76723780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60543
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Outer mitochondrial membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
TTC39A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597213
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colon transversum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
BRD-K06094529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61621
BRD-K56870337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26135
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2779
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K52083268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13114
MBTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0436
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7780220-12943_2020_1301_MOESM8_ESM.xlsx-Fig_3A_RNA-seq_DEGs-Summary_701_LPS-induced_DEGs_361_THZ1-sensitive_DEGs_in_blue_of_macrophages_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_3H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14915
BRD-K77465015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22316
MOLM13	DepMap CRISPR Gene Dependency	1.0	2.04956
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78972225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95894
increased circulating phosphate level	IMPC Knockout Mouse Phenotypes	1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54683
protein-containing complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K74095559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06245
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
nitrate reductase activity	GO Molecular Function Annotations 2025	1.0	null
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12658036-41598_2025_25964_MOESM5_ESM.xlsx-Sheet1-Supplementary_Table_1_The_list_of_546_proteins_specific_to_pLV3-CMV-AR-TurboID_H2O2_group_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
fh4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
BRD-K39476596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76245
BRD-K00081911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17225
BRD-K36074653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65576
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
nitrite reductase (NO-forming) activity	GO Molecular Function Annotations 2025	1.0	null
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16911140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.04738
AKR1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622803
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mitochondrial outer membrane	GO Cellular Component Annotations 2025	1.0	null
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6576
BRD-A17120244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13114
EGFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00288834
PHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83187
GSE218727_0_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00946
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00382972
CSNK1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00384748
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81758631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53753
BRD-K34489843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70943
CCL17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00679122
NCIH747	DepMap CRISPR Gene Dependency	1.0	3.55906
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31232
VPS13B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00779544
MICOS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.636
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0275
NEFM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487562
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210093_0_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRTC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00575374
BRD-K48592348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57671
Dimethyl sulfoxide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.707
BRD-K50300854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1826
LDHC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00440582
DCN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542019
BRD-K93127164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72344
SDC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00668874
BRD-K24259871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07877
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Percent liver fat	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
LTB4R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00622554
BRD-K34506374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04208
nitric oxide biosynthetic process	GO Biological Process Annotations 2025	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
KCTD12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00689097
LACC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507339
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRKCG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671145
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TNFSF14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00574745
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.1576
BRD-K01757377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84728
BRD-K58876832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7898
BRD-K91239327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28009
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30765
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38763
GSE183327,GSE183328_3_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15546
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nitric-oxide synthase complex	GO Cellular Component Annotations 2023	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8397
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.41653
PMC11024792-DataSheet_1.pdf-33-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05002
S100Z	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661046
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99826
Mitochondrial outer membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SERPINB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36957
BRD-A89681034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09509
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04312
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ORAI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00396554
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203329_2_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K38610362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18659
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7464
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1637
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IBMX	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68907
CRCGN015_MCF10A_48H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03745
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2511
BRD-K30022119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89605
SEC14L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496477
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A76076412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33563
GSE229973_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50176
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K45378289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18656
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NOTCH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00393004
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NarGHI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
increased circulating creatinine level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A04618830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03254
NPY5R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00436847
PFKFB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00740467
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
PRDX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00757156
S100A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467056
BRD-K57051157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67697
BRD-K25322420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46991
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7187
EFNA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514922
SLC22A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063748
Outer membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37626
HAPLN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641411
TPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31628
LIVF001-025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99257
BRD-K05841284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51055
BRD-K65875972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44556
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MERO41	DepMap CRISPR Gene Dependency	1.0	4.90772
Hepatic stellate cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.302
BRD-K63134971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36098
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.91666
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KARPAS299	DepMap CRISPR Gene Dependency	1.0	3.19975
DLD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00460143
GSE207301,GSE207303_1_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76342376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05926
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45053
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CLEC4E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594207
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00662
GSE140965_2_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Phase I - Functionalization of compounds	Reactome Pathways 2024	1.0	null
PMC4063835-epi-9-760-s02.xls-MI_vs_NU-SYMBOL_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE209698_0_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
B9D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450081
BRD-K98005735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44765
BRD-K41135617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55457
GOLGA8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00405539
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K22915992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14684
AQP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00846133
GSE147876,GSE147877_4_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K58955712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2378
FLI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055469
PMC11385366-Table2.xlsx-DBP-Overlapped_Gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231875_0_v_1_zbed3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE74383_2_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IDH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00629745
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SEMA4C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00640967
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Angiomyolipoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16145
BRD-K58944125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17848
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A88461048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87794
BRD-K87080069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57571
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17733
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A57536034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17332
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JMJD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549209
LIG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00718906
Triglyceride levels in current drinkers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GPATCH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519544
T3M5	DepMap CRISPR Gene Dependency	1.0	2.09404
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
SYNM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669539
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
nitrate reductase activity	GO Molecular Function Annotations 2023	1.0	null
BRD-A80968824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28417
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2352
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52
BRD-K66807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37065
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PTPRJ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536403
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72296840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11966
TRUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21118
MANBA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00417913
bp86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
BRD-K79887735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50486
HEY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480426
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_10_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_14_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
FABP6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00635772
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
Xanthine dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.767
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.65229
BRD-K49029187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05543
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SU8686	DepMap CRISPR Gene Dependency	1.0	3.35271
BRD-A58937872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12891
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP6V1C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540614
BRD-K06399794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42842
GSE211151_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24748
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48702
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sbc2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
IGSF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579833
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K94855649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94749
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE80182_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36421
AMPD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580598
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DU4475	DepMap CRISPR Gene Dependency	1.0	3.13238
BRD-K36883526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35413
BRD-K70558130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02013
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rennet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
BRD-K50819157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08488
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36157
BRD-K38737333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29466
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K16357911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03317
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABRD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557167
WRAP53	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00524015
S1PR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00476787
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDL cholesterol levels in current drinkers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.02218
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4A-Down_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210476_11_v_10_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
t60-adrenal_male_1w	MoTrPAC Rat Endurance Exercise Training	1.0	2.20603
BRD-K97595801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69997
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34542210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46818
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1039
LPS141	DepMap CRISPR Gene Dependency	1.0	3.04356
SLC30A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00663801
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58466
CRCGN012_HEPG2_24H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32236
BRD-K87023633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60528
BRD-K21386594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18589
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7754
BRD-K08927194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12384
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA3_FOXA3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PRSS8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00568323
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K14907323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91643
L-cysteine desulfurase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.927
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
Aspartate aminotransferase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K34573818	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78621
Serum alkaline phosphatase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
BRD-K86893953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98766
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COL4A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00771266
Adrenal gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SSTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594171
BRD-K36170990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3128
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA2_FOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE264010_0_v_1_parp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
DOT1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0034911
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GCGR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00627783
BRD-K45609222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3242
BRD-K16884266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75754
ATIC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513483
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46749
BRD-K23220745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6589
LTB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00633615
GSE185519_1_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K30973947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.502
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77401804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05504
GSE196962_4_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MICU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35886
BRD-K57969466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51026
GSE242290_1_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176008_4_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS27A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00899318
CALR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657446
BRD-K86998514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32981
BRD-K30589514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25938
TPMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.004614
CRCGN015_MCF10A_48H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19879
BRD-K69671285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10546
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GALE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00451484
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31210612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12726
ABCA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595352
BRD-K93752373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26264
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	1.0	null
SAM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.36
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.62813
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38622
PMC11906621-41598_2025_93656_MOESM6_ESM.pdf-29-IRF7_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:G03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08107
BRD-K47087435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3331
BRD-K50712773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48763
BRD-K99939253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12202
BRD-K69903018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4327
BRD-K32965188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32572
BRD-K29458940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02407
PMC7064337-elife-51373-supp2.xlsx-652_genes_up-regulated-List_of_652_genes_up-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PAK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0063483
BRD-K85271599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25236
PMC2965092-pone.0013658.s001.xls-Liangos_SOM_Table1-GeneName_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39639513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13799
BRD-K82814367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86977
High density lipoprotein cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
VCAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00777928
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.25749
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.912
TCOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05393
Pancreas	GTEx Tissue Gene Expression Profiles 2023	1.0	4.333
BRD-K50212643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.69318
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TIPARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14815
GSE185953_2_v_0_tlr3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36796440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5228
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.88783
increased blood urea nitrogen level	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K37790543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3349
HCC515	DepMap CRISPR Gene Dependency	1.0	2.14748
GSE231891_5_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79712504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64667
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	6.1417
CTTNBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00696501
SLITRK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00562672
rene1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
TMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12592
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM71	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00506498
NPIPB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38527
GSE165307_3_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0757
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2254
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6796
PIK3AP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00687749
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88645787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94935
BRD-A64849281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38852
BRD-K51012353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00083
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VTCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00700334
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nitrite reductase (NO-forming) activity	GO Molecular Function Annotations 2023	1.0	null
mitochondrial membrane	GO Cellular Component Annotations 2025	1.0	null
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13895
BRD-K90858591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50821
ALK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506584
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-LEF1_UP_V1_DN-Ensemble_gene_ID_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3332
GAD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554696
GSE193258,GSE193259_9_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38932508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09974
nitric-oxide synthase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K78995236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20449
Collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.639
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22938
BRD-K15800236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06832
BRD-K21412601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37843
CRCGN017_MCF10A.TP53.M_24H:I18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37101
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GZMA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514722
BRD-K96549574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33639
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23971
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188382_4_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217990_0_v_1_rnmt_human	RummaGEO Gene Perturbation Signatures	1.0	null
P2RY4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051452
Metabolism	Reactome Pathways 2024	1.0	null
TBX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00424868
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00416864
PMC11076560-42003_2024_6230_MOESM5_ESM.pdf-42-ZNF589_ZNF589	Rummagene Transcription Factor Associations 2026	1.0	null
TOP2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00667943
KNG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703088
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19642
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4829
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OV7	DepMap CRISPR Gene Dependency	1.0	2.34974
BRD-K68401280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09248
VHLL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00698348
BRD-K23831817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96961
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC158	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058084
GSE158834_10_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34018
NCF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00770986
BRD-K35383890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93814
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LDL cholesterol	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0301
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79777851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13443
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_3_TurboID_1hr_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
PSS008	DepMap CRISPR Gene Dependency	1.0	3.01854
WEE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467124
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31408750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88903
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-260_ChIP-Seq_H3K9me1_2_AR_differential_down_regulation_upon_KDM3A_or_AR_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45383509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17272
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_5_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38688
BRD-K86855109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26412
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02100640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3594
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
nitric oxide metabolic process	GO Biological Process Annotations 2025	1.0	null
BTF3P11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584431
STK17A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523798
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0553
GSE200897_1_v_0_pold1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82145108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14887
CRCGN014_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.97593
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25953
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39597
STK25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00354634
mannosyl-oligosaccharide 1,2-alpha-mannosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.15
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K17107214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84995
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BAD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00488316
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.35871
GSE232261,GSE232263_0_v_1_usf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ADRB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00453526
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NSD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607329
molybdenum ion binding	GO Molecular Function Annotations 2025	1.0	null
ACTR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00402
BRD-K28184331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25974
KARPAS1718	DepMap CRISPR Gene Dependency	1.0	2.33306
NELFA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620195
GSE202434,GSE202438_13_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4766
CRCGN011_HEPG2_24H:H16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05275
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14913
NEO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00581292
BRD-K77706833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34632
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.647335
BRD-K96979108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6336
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CHRNA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651446
CRCGN013_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6992
MDAMB453	DepMap CRISPR Gene Dependency	1.0	5.97378
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K80819226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50374
RLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07481
GTEx Skin 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-6.02549
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.51571
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8759131-advancesADV2021004469-suppl2.xlsx-Table_S1-Supplementary_Table_1_Differentially_expressed_genes_post_knockout_of_MEF2D_in_MOLM-13_AML_cells_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41939184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19613
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15082
GSE178714_3_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4101
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NME3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518558
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14788
BRD-K34985075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00305
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3244
CRCGN008_HEPG2_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48065
BRD-K87595216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09278
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7501
DLAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584264
GSE205976,GSE205978_3_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEP72	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651664
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06786
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
S100A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612813
IGSF6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570845
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NB1643	DepMap CRISPR Gene Dependency	1.0	3.80452
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34583
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9532
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComUP-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130401_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K86981519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72134
AREG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571662
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133516_5_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K50718861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0775
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K33350866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27093
BRD-K28601178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64481
BRD-K29820234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06046
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48619
APEX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558313
BRD-K36027285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11325
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165548_2_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ITGB1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89499
PLCG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00649785
BRD-K81475473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29307
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K99581286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1779
GSE186460_3_v_6_baricitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LRRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00831466
BHT101	DepMap CRISPR Gene Dependency	1.0	3.0789
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKAPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24013
BRD-K70148902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27831
BRD-K56086519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34494
CCDC141	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00621177
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10318747-12864_2023_9472_MOESM2_ESM.xlsx-OCI-AML3_30min_vs_Control-Unnamed_1_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC56	DepMap CRISPR Gene Dependency	1.0	2.123
GSE158834_11_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MTIF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28026
IRX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06624
SELPLG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00563263
BRD-A94885304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71342
BRD-K98731550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51551
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39600742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17245
BRD-K06577881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3225
BRD-K69184209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51224
CLK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00596061
PSMB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00498824
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25422
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nitrite reductase activity	GO Molecular Function Annotations 2023	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K12106433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01229
BRD-K17065706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05448
SNU387	DepMap CRISPR Gene Dependency	1.0	2.57978
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3792
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_5_TbID_-biotin_ERM_proteo-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-LEF1_UP_V1_DN-Gene_name_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49201
BRD-K33495825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25602
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12062214-41467_2025_59646_MOESM5_ESM.xlsx-HMGA2_activated_repressed-Gene_symbol_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5585
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
DETROIT562	DepMap CRISPR Gene Dependency	1.0	5.08904
oxoacid metabolic process	GO Biological Process Annotations 2023	1.0	null
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K44648112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54742
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42438
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14845
BRD-K98890753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58359
ModE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
BRD-K46065636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05535
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26117128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17868
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142430_3_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35123860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17267
Coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
BRD-K15098674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0052
BRD-K90049800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5666
BRD-K47536398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96886
BRD-K37616496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57993
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04534
BRD-K90562751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43258
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.03527
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFM19	DepMap CRISPR Gene Dependency	1.0	6.171
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
TSGA10IP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602117
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12685
gentamycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.36876
SKM-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K32445732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05348
BRD-K95709431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.033
HLA-DOB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00592426
MDS-L cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
LENEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00522283
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sporulated oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K05409106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07759
BRD-K54212583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11969
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.33783
ADRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522622
BRD-A62469171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25996
BRD-K52473839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29383
BRD-K72083510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2397
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.37449
RDX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00460334
BRD-K73296174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19326
C11orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06397
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BIRC7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588991
BRD-K28522188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78094
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16776
GSE143662_0_v_1_dcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91879432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55897
BRD-K62533881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24236
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47895166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2394
BRD-K27671601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66859
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.76541
increased spleen weight	IMPC Knockout Mouse Phenotypes	1.0	null
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178714_3_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PDE5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564212
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6263
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-SOX2-Unnamed_3_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC85B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00356314
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
AHRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4277
MAP3K8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00621661
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
HMV-II cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2701
nitrite reductase activity	GO Molecular Function Annotations 2025	1.0	null
TET1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536737
BRD-K85294251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86934
Inguinal canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04593
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor	GO Molecular Function Annotations 2023	1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor	GO Molecular Function Annotations 2025	1.0	null
ITPKC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497563
BOC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567092
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06776
BRD-K54506283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18423
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EIF4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00867938
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.71632
CRCGN008_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6058
ADCK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585262
BRD-K10135449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19793
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29684
FEZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00430018
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51370144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13103
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.33775
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9961
Stomach	GTEx Tissue Gene Expression Profiles 2023	1.0	1.85402
BRD-K44743425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34251
BRD-A56427952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1942
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K37906141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07896
PANC1005	DepMap CRISPR Gene Dependency	1.0	2.89632
RDH8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00761724
BRD-K96106084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88797
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32051
BRD-K53816426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70939
GSE175787_13_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
TSPAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44717
BRD-K52245873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65559
PMC10537816-12967_2023_4509_MOESM1_ESM.xlsx-ST18-Unnamed_4_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
NETO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0073598
PMC6888893-41422_2019_228_MOESM6_ESM.xlsx-genes_correlated_with_RUNX1-Table_S1_-_Genes_correlated_with_RUNX1_in_aECs_Related_to_Fig_2_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86716312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03802
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73587
ECT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3968
PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K59002219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40347
BRD-K86330848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19403
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
iron-sulfur cluster assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.53
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null