association	dataset	threshold value	standardized value
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1650	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61417
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0639
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.12735
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45114
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6757
Poisoning	CTD Gene-Disease Associations	1.0	1.19312
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02708
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51972131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32887
IGR1	DepMap CRISPR Gene Dependency	1.0	8.31848
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63889
BRD-K99210277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.61655
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.884016
Gonadal sheath cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
3'-fluorobenzylspiperone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15545
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.993444
protein binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835174
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35028
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A655-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2722-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr8_11340089_T_C_b38	GTEx eQTL 2025	1.0	1.83859
Coelomocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0196
BRD-K62219570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76117
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54633
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.11843
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15938
BRD-K76628522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31389
Endometriosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.929
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.896421
HUH6	DepMap CRISPR Gene Dependency	1.0	4.00182
BRD-K54934070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12831
ONECUT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7253
non-Hodgkin lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
PIK3CA_druginhibition_57_GSE17785	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.64062
BRD-K53552465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38757
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2534
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03322
PAX6	ChEA Transcription Factor Targets	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826464
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_SB431542_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127817
MASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77132
GSE101527_0_v_1_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K84792324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29842
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59632
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05254
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46943
BRD-K57359365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27725
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11459127-pnas.2406837121.sd04.xlsx-Sheet1-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32472782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00047
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1865
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6014
peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.185016
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07821
HCC2157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3969
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17615
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11703_KD_MIR31HG_SRP051359	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.2936
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.51311
hsa-miR-4704-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05172
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37838
PHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26223
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929781
NRL_Deficiency_GDS2936_629_mouse_Retinas - 2 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
regulation of phosphatidylinositol dephosphorylation	GO Biological Process Annotations 2023	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2595
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.927305
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45114
BRD-K08730943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55186
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07244
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-556-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.840469
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14787
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
3086_FIP1L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.863086
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.83864
r5 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35063
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.709
pi3p	GeneRIF Biological Term Annotations	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
SARS-CoV_24Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.62241
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Cimetidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161134
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8658
A549_MC1568_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203343
BC3C	CCLE Cell Line Gene CNV Profiles	1.0	1.46726
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041912
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14067
r8 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37573
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU245	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80236
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU478	DepMap CRISPR Gene Dependency	1.0	2.93101
Nutrition disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.95
GSE135350_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE139540_0_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27411
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.94274
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73268
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156818
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242083,GSE242098_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.9582
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2464
GTEx Heart 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-9.21236
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00372
NCIH211	DepMap CRISPR Gene Dependency	1.0	3.12135
Perturb_4322_KO_Fmn2_SRP109283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.85047
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5916
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85303
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33542
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-0.826653
BRD-K47160864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27972
GABP-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66424
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4234
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84144
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GABP-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72164
FOXA1-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rh30	HPA Cell Line Gene Expression Profiles	1.0	1.29379
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM24_knockout_298_GDS3087	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.93367
K562_Aminoglutethimide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154301
Necrosis	CTD Gene-Disease Associations	1.0	1.61107
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3545-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Charcot-Marie-Tooth disease type 4B2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10838
GSE87299_1_v_0_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3942-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
RSV_24Hour_19459069_GSE3397	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.40392
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26629
BRD-K39617634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03042
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Generalized epilepsy with febrile seizures plus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964335
BRD-K32037893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11922
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2271
Bipolar Disorder_Cerebral cortex_GSE12649	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.7331
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839408
GSE261563_5_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958479
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284115
obesity	GWASdb SNP-Phenotype Associations	1.0	1.14406
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66438
BRD-K97943226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14074
S100A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11387
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAMP_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HSD17B7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14441
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thrombocytopenia_Megakaryocyte_GSE2527	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.94097
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE203131_0_v_1_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.133912
BRD-K80715600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70772
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26402
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884196
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Charcot-Marie-Tooth disease type 4B3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.596
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80495774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10067
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05487
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69903198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03289
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838117
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.53314
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26266
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31110422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30159
hsa-miR-130a	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
FOS	ENCODE Transcription Factor Targets	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08692
BRD-K48372955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05969
KYSE-150 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16088
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4852
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80439500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0687
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3034
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875908
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65954
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Divalproex Sodium_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162767
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rpmi8226	HPA Cell Line Gene Expression Profiles	-1.0	-0.989548
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4658
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987569
protein stabilization	GO Biological Process Annotations 2025	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.210589
TBP	ENCODE Transcription Factor Targets	1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1831
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14369
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00245
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909357
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.06808
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26921
PC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57995
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_430_KD_FOXM1_SRP371675	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC5130036-oncotarget-07-40690-s006.csv--AR_signature_for_GSEA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06763
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE208226,GSE208227_2_v_1_ell3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845178
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31328
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.899
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18262
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3614
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2483
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988332
SARS-BatSRBD_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.43244
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909384
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21116
BRD-K12913157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78391
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11726
hsa-miR-4668-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
BRD-K22789469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27836
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987446
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VN(H5N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69552
PMC9314343-41467_2022_31892_MOESM8_ESM.xlsx-Fig7e-CTCF_in_promoter_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3082
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.54702
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859156
BRD-K11589884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19941
Adventurousness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25131
MELK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00293987
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843143
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979001
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K65831955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02765
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1755	DepMap CRISPR Gene Dependency	1.0	2.70508
BRD-K02844551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15214
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05385
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4737-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00300115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28462
PMC8166871__F7	PFOCR Pathway Figure Associations 2024	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dot1l_DELETION_GDS4295_426_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 3 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25234
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
COLO783	CCLE Cell Line Gene CNV Profiles	1.0	1.55177
COV434	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964059
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-20-UU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211402
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11886
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03584
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.91862
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0778
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84226
AA-56-QO38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283551
POLDIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21948
CTCFL	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD4_druginhibition_224_GSE50865	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.13778
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890205
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5144
BRD-K90746817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06738
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2464
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838157
Achalasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.127
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A954-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226249_2_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.91733
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16139
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Phosphatidylinositol 3-kinase complex, class II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.224
NCI-H1092	GDSC Cell Line Gene Expression Profiles	1.0	1.48408
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6619
hsa-miR-335	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0434
SIRT6	ENCODE Transcription Factor Targets	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_2_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01128
GSE261563_7_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2166
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
ABL1_knockdown_144_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.916394
BRD-K65257143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6579
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11557
DAN-G	COSMIC Cell Line Gene CNV Profiles	1.0	2.14311
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858557
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56065989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53282
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4SY-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883037
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2445
NH6	CCLE Cell Line Gene Expression Profiles	1.0	1.52123
BRD-K44427106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47531
BRD-K62418408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30537
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832234
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72362
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928548
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18967
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70254692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40298
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.48012
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13868
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
BRD-K15427120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12607
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8630-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12845
hsa-miR-32	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24504
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12926
NRF1	ENCODE Transcription Factor Targets	1.0	null
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.132138
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06999
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08233
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.1253
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886463
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90653
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
Perturb_12219_KD_EPRS_SRP073504	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.1747
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-4671-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
SEC24A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08291
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.0716
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51504
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3057
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58115
BRD-K58890106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26148
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39765
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS742T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91583
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36074
GSE87299_2_v_3_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01511
hsa-miR-330-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
BRD-K69077676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43774
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01629
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78663
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CC-93-RP38_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339889
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925395
MKN7	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15613
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09208
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09403
Fetal Death	CTD Gene-Disease Associations	1.0	1.42238
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50517
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39547
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25715
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68665079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29294
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Glesatinib(MGCD265)_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019906
metabolic	GAD High Level Gene-Disease Associations	1.0	0.295739
BRD-K53356402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71115
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Sorafenib Tosylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131255
BRD-K54785691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31903
BRD-K61807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5022
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11158
SKPNDW	DepMap CRISPR Gene Dependency	1.0	2.60822
hsa-miR-4310	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
BRD-K65913831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26647
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.7151
17597811-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
ZNF488	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59061
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31886
A704_KIDNEY	CCLE Cell Line Proteomics	1.0	2.51515
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26342
BRD-K00610900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38231
ZC3H11A_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.4715
CDC7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507474
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15847
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5732
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25237
BRD-K27953820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36416
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19808
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13583
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04341
BRD-K64742599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11364
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26051
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29903
ETS1	ENCODE Transcription Factor Targets	1.0	null
Macropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.265
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.398589
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t-cell chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96146
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA-bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6268
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2949
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49136
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
DANG	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
DF-00-BX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279432
K562_UNC0379_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173885
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.67675
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of dephosphorylation	GO Biological Process Annotations 2023	1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00759
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280104
KDM5B	ENCODE Transcription Factor Targets	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10274745-media-4.xlsx-S3A-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51033
GSE161302,GSE161304_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_H_sapiens_970_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0199
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853787
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.999514
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6459_KD_LKB1_SRP094725	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.3034
BICR16	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72538
A549_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144637
TBX5	ChEA Transcription Factor Targets	1.0	null
BRD-K51919154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18405
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5714
BRD-K50950731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36179
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.746
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97819
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28909
phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8077
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
859_BMS1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.842098
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.944286
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5155
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.36211
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041246
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3591-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11432
H4K20me1_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00455
BRD-K07914894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73729
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06627
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27106
enhances	GeneRIF Biological Term Annotations	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.983761
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2856
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72488042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14383
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.897371
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MDAMB468_BREAST	CCLE Cell Line Proteomics	1.0	2.64758
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09842
HSPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15543
APLP2_KO_GDS4414_534_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.514852
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MEF2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36821
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28543
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.265
BRD-K78347804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60238
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042814
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041062
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.876688
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3119
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8217
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886393
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27742
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21332
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3667
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K70163662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36681
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65557
BRD-K19237647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08777
HDAC1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-501-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926543
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50058
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65548
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25203
KAT2B	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0325
SARS-CoV_96Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65017
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K57200567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99792
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8607
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.233
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.286
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33377
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SU-DHL-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE75976_3_v_4_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.982084
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65993
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14768
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5232
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26962
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.996196
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41818
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26267
RDH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22603
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PV-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8351524-CTM2-11-e522-s024.docx-0-REST_REST	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190555,GSE190557_2_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6433
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.884102
avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SDF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61732
PMC11814113-41467_2024_55326_MOESM3_ESM.xlsx-BP_Dorsalgia_GTExQTL_loci_MR-Unnamed_12_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inositol phosphate metabolism	KEGG Pathways 2026	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH661_LUNG	CCLE Cell Line Proteomics	1.0	2.11099
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3452
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4203
BRD-K72588970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51234
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Obesity	HuGE Navigator Gene-Phenotype Associations	1.0	null
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38279
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908044
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PC3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64892
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10198
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Overnutrition	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.95
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mantle zone of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57525
abnormality of body weight	GWASdb SNP-Phenotype Associations	1.0	0.393189
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15193
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09376533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12475
GLMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.613
Breast Cancer_Mammary Gland Tissue_GSE1872	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53116
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0536
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22897
POU5F1-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE198165,GSE198166_7_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.935254
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.75927
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36263
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06497
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890292
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLHL14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00415839
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69131
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JV-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888561
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A23R-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05055
liver	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05132
MMADHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38563
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923536
MAFF	ENCODE Transcription Factor Targets	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_WHI-P154_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148881
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31458
C32_SKIN	CCLE Cell Line Proteomics	1.0	3.66549
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
Centronuclear myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.081
negative regulation of autophagy	GO Biological Process Annotations 2023	1.0	null
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00511
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.5458
Phosphatidylinositol 3-kinase complex, class III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.9048
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96798
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE255680_1_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80878
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59391
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138050,GSE148257_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842675
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dok	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11932
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952284
Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
generalized epilepsy with febrile seizures plus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0732
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.887311
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25272
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4645
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33289
BRD-K15940717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01054
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.225504
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.36296
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glucose	GeneRIF Biological Term Annotations	1.0	null
NCIH2023	CCLE Cell Line Gene CNV Profiles	1.0	2.34649
BRD-K85235446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17561
BRD-K03035008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40212
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48749255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63407
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04034
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38035271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03225
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53988
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MG-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-548aa	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.865246
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03597
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K45428339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59212
BRD-K41793515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45386
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81268
GSE131649_4_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
HCC70	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15294
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0712
BRD-K24035524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13423
K562_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0255866
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.11789
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9117
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.943777
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.867485
increased body weight	GWASdb SNP-Phenotype Associations	1.0	1.14406
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.808272
nifenazone-2122	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of macromolecule metabolic process	GO Biological Process Annotations 2025	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31122616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41629
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.929
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-1261	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33973
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4412
BHLHA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53303
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19979
BRD-K75576005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12332
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60394
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15185
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72538
BRD-K30566330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18878
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2295
hsa-miR-326	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37478
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2758
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91351
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917947
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25222
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968527
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.177
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Miles-Carpenter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BV-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42631
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19904
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97797
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4461	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23698
BRD-A12725272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50654
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79561909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01176
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36074653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65962
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VPS26B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08749
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary spastic paraplegia 37	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
hsa-miR-3614-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K51153795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57442
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZS-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A65806553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12811
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23446
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16725
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38228
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23647
BRD-K21450593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.34462
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Esophageal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48699
BMPR1A_knockout_222_GSE48092	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.16842
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
15831697-TableS2	GeneSigDB Published Gene Signatures	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48134
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0207852
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858006
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86767
BRD-K16791544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.14517
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K30772101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13202
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
FLI1	ENCODE Transcription Factor Targets	1.0	null
BRD-K72533381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24365
GTEx Brain 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-12.545
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO3	ChEA Transcription Factor Targets	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26974
Cytoskeleton organization and intracellular signaling	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
BRD-K71521842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48225
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.908797
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909384
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51490423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34858
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34672
BRD-K98598055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36252
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_unique_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.07163
Brain Lower Grade Glioma_LGG_TCGA-DB-5279-01A-03R-2347-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	1.54094
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14114
Mitochondrial fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92454
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08492
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
phosphatidylinositol metabolic process	GO Biological Process Annotations 2025	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3120-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
FMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29352
hsa-miR-2682	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04725
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82474
BRD-K62288678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04482
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7617
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-340	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STK33_NOMO	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26995
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
positive regulation of phosphatase activity	GO Biological Process Annotations 2023	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245924
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67846
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02375
BRD-K81656074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66785
BRD-K14416602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66798
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.20921
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.13007
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37047
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13318
BRD-K37507671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75809
BRD-K58827489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6241
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47814830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15474
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inositol phosphate metabolism	Reactome Pathways 2024	1.0	null
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28472865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14839
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27554804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64634
GSE196540,GSE196542_2_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9393_KD_RAD21_SRP071219	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.45962
Perturb_15603_KO_CypD_SRP298064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.69076
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56418
Diabetes, Gestational	HuGE Navigator Gene-Phenotype Associations	1.0	null
Fish- and plant-related diet	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972387
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833687
neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.221793
ETV1_01_36	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.89928
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84528
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448604
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
GTEx BloodVessel 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-6.27909
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4262	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inverted papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
CREB1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AA-46-GL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.561017
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91996
ECC10	CCLE Cell Line Gene CNV Profiles	1.0	1.64371
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39678
BRD-K19603900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0183
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44067
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845047
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903109
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31086
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11471
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06067
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08166
BRD-K89366259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34554
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21652
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.08478
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33321
outer SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.213
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6336
PA-1	GDSC Cell Line Gene Expression Profiles	1.0	1.62241
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973408
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.69062
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51713
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.287415
BRD-K66762690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12383
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827014
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35704
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894078
BRD-K54742099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0047
1011_C18ORF21_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.16493
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7379-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09342
BRD-K53224741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84177
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35863275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13934
MANBA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00417555
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	1.0	2.92546
BRD-K49490091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23421
CTCF	ENCODE Transcription Factor Targets	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951049
CAL-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
17555561-Table2	GeneSigDB Published Gene Signatures	1.0	null
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11227
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.024082
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MELHO	DepMap CRISPR Gene Dependency	1.0	6.12221
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3050_FDPS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.682871
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40681
KMRC20	DepMap CRISPR Gene Dependency	1.0	2.47552
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39611
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882798
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204935
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03672
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09224
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.67216
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12322
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02899
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.40007
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08143
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06719105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31714
BRD-K76672145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55725
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18309
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.1653
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77083
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Common_up-regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH684	CCLE Cell Line Gene Expression Profiles	-1.0	-2.62145
GTEX-RU1J-1326-SM-46MUL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06874
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.09435
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45212
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4772-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K33283629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13045
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2298
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30506
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12635
BRD-K27638063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76286
16818684-Table2c	GeneSigDB Published Gene Signatures	1.0	null
macropinocytosis	GeneRIF Biological Term Annotations	1.0	null
GSE131649_4_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19155
Hereditary spastic paraplegia 45	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
BRD-K16411174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26955
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.935108
AE-32-NZ70_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317501
BRD-K17234088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15659
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5504
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62294866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18298
Perturb_17553_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TRIM28	ENCODE Transcription Factor Targets	1.0	null
AE-06-FY47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204783
BRD-K70537701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49211
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.936936
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K46739745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55418
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6699
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51635
Obesity	DisGeNET Gene-Disease Associations	1.0	null
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Processed meat consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
MYOG	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54604
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal dominant intellectual developmental disorder 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
hsa-miR-449c	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60517939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13481
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839526
Tail fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
TE-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53892
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3821
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3921	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
metabolic	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WX-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908013
Perturb_14001_OE_DNMT3L_SRP279231	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.55239
GSE141453,GSE141454_0_v_4_card11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nemaline Myopathy_Gastrocnemius Muscle_GSE3384	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.07039
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00523
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14077
hsa-miR-3591-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
A549_Entacapone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014792
17724462-TableS1	GeneSigDB Published Gene Signatures	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66576
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0568
SISO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00768
BRD-K04272258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04348
SNU-C1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.9836
PMC4944136-srep28995-s2.xls-NOBOX-gene_NOBOX	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26013
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07453
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00709
hsa-miR-3671	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3284
ZFX	ChEA Transcription Factor Targets	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.34624
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06807
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.963635
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-fig-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Adenocarcinoma of lung_Lung Tissue_GSE1037	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.37998
hsa-miR-1825	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913929
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4237
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6379
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.124
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864978
BRD-K38955287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23354
BRD-K71755682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57661
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5355-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOP1MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03034
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19225
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30219
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-92b	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88595
BRD-K17233342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97048
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884657
BRD-A67788537_Salermide_A549_6.0_h_120.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC202	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98439
hsa-miR-544	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41484
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00146
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23958
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Amylin receptor complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZZZ3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4251
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873011
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXI1-33610681-GES1-HUMAN-GASTRIC-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07974
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24467
GSE48812_3_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal dominant Robinow syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158853_0_v_1_hmgcs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23953
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18759
BRD-K15882320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14555
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_54_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15073
BRD-K51465424_Ritodrine hydrochloride_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915721
Perturb_7679_KD_NBAS_SRP267245	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SJSA-1	GDSC Cell Line Gene Expression Profiles	1.0	2.32601
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.83781
BRD-K34158806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35422
BRD-K12011077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12192
BRD-K51566146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59321
ACF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.537
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24D-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_INO-1001_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161292
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8491
BRD-K28874552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26127
JUND	ENCODE Transcription Factor Targets	1.0	null
OCILY18	DepMap CRISPR Gene Dependency	1.0	2.32008
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00324
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71493640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09791
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.547326
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7031
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49207204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03404
CBX3	ENCODE Transcription Factor Targets	1.0	null
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52751
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919919
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27516
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.29889
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46636
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207962
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45979235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60364
enzyme regulator activity	GO Molecular Function Annotations 2015	1.0	null
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61233
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05266
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29983
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-301b	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93032100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69978
BRD-K66735566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31819
BRD-K45272675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34718
hsa-miR-633	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92734
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9857	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49685
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31437957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03731
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	2.07014
Learning Disorders	CTD Gene-Disease Associations	1.0	1.57234
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CDK2_knockdown_146_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.07437
GSU	CCLE Cell Line Gene CNV Profiles	1.0	1.60509
chlortalidone-7152	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44499
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.754856
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT29	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77553
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72706
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4198
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12700546-jci-135-197583-s034.xlsx-ST18-Unnamed_2_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7998_KO_Scrib/Taz/Yap1_SRP265287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.17692
Metabolic Syndrome X	DisGeNET Gene-Disease Associations	1.0	null
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.921334
SARS-CoV MA15_Day2-C57BL6_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.978703
4,4'-Dimethoxybenzil	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
BRD-K89394474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38714
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06868
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.95
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-578	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
Extraversion	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50139
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06981
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K24308170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.537
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48308
K562_AICAR_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187175
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
BRD-K61206648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18108
BRD-K72609445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01876
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
patu8902	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.277
BRD-K33236055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33236
Bone ultrasound measurement (broadband ultrasound attenuation)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-STAT3_target_genes_in_N1-GOPC_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
SNU601	DepMap CRISPR Gene Dependency	1.0	4.70513
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65275
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1744
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NME6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14301
HFL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
hsa-miR-4435	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20665
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
icSARS CoV_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.859202
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5586
hsa-miR-181a	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
BRD-K26682747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82025
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.519
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4436b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56024344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07575
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.412182
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05631
variations	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2834-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00032
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSK3B_knockdown_204_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.36392
hsa-miR-4446-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
superficial stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53116
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72538
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EWSR1	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16397
Idiopathic generalized epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66862
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dyslipidemias	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30016
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03813
HT115_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.07171
BRD-K38450726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13578
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1635
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940583
HCC2814	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66425
scg3	GeneRIF Biological Term Annotations	1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2835
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.856284
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873173
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.825651
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1074
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52559
Charcot-Marie-Tooth disease type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.576
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Crizotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115935
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SHP-77	GDSC Cell Line Gene Expression Profiles	1.0	1.88109
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06704
MedullaOblongata	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.980438
FOXP2	ENCODE Transcription Factor Targets	1.0	null
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
BRD-K65932559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51721
IRF3	ENCODE Transcription Factor Targets	1.0	null
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.913
idiopathic generalized epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.887618
HCC70	GDSC Cell Line Gene Expression Profiles	-1.0	-1.98703
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3909	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MXI1	ENCODE Transcription Factor Targets	1.0	null
BRD-K08715132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32592
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02811
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09141
KP-N-RT-BM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938479
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43263
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00709
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325169
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.17
hsa-miR-4789-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NB-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829114
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K35671498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89598
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
palmatine-chloride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40946
EP300_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82064887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24211
measures	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4751	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
negative regulation of autophagy	GO Biological Process Annotations 2025	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22667
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.974478
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4141
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2299
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853376
ataxia	MGI Mouse Phenotype Associations 2023	1.0	null
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
6553_POLR2L_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.585145
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2246
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22043
Centrosome	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
POU2F1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K85965830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6803
A204	BioGPS Cell Line Gene Expression Profiles	1.0	1.55891
A549_Belinostat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134798
ETS1	ChEA Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polymorphism	GeneRIF Biological Term Annotations	1.0	null
BRD-K47062996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64938
K562_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174586
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
preweaning lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Angioblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
BRD-K96547094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06986
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27092365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27998
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03039
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K52492854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64737
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1074
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_triplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
Insulin Resistance	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66727
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21282
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28585
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03689
intracellular part	GO Cellular Component Annotations 2015	1.0	null
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282304
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54283
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252165
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.78413
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0562
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15243
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-299-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75821161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29362
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.449
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05249
CREB1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGBC11TKB	GDSC Cell Line Gene Expression Profiles	-1.0	-3.53725
GTF2B	ENCODE Transcription Factor Targets	1.0	null
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54338
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20284960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2998
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPG21	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9773_KO_Tkt_SRP313974	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.94628
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09676
Charcot-Marie-Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9673
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	162.295
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K20196153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22906
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12642
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Subesophageal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21346
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3332
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44324
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00431
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164463_4_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10863
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5873
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44487
BRD-K70302892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30753
BRD-K07365255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05761
GSE239844_4_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85168571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26684
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51312
hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.145113
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4422
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35692
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10003
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04977
hsa-miR-580	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64663
BRD-K73809982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03721
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00522
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A2QG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2526
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K89837874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48755
Perturb_1756_KO_Ripk3_SRP226420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K90649428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42458
ASS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00344131
Anterior horn cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
TCF4	ChEA Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.994364
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27895
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7657_SARS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.864248
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72164
periventricular stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35063
Lung adenocarcinoma_LUAD_TCGA-86-7711-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX3_01_27	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.08096
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26395
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5102-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248887_0_v_1_dkk1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31725
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00265832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00707
BRD-K66089377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16172
K562_GSK1070916_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139783
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06887
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08658
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0282
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	2.59971
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12192
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.871521
VPS37D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02823
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.23697
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311869
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6038
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-499a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.736419
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61233
Lung squamous cell carcinoma_LUSC_TCGA-18-3407-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.391
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Sodium Phenylbutyrate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166279
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7364
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.932129
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.21011
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-25	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
JHH4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0606
KDM5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39772
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
BRD-K96708215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20209
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2497
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5296
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040821
General factor of neuroticism	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CB-83-LF14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422047
Oligospermia	CTD Gene-Disease Associations	1.0	1.20784
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366493
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43813
BRD-K25718133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07754
A549_Bisindolylmaleimide IX_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158296
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYNJ2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35357
ASH2L	ChEA Transcription Factor Targets	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHEK1_knockdown_142_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.9222
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01647
hsa-miR-515-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11030494-media-2.xlsx-ST12-Supplementary_Table_12_Genes_identified_by_MAGMA_as_being_significantly_associated_with_the_internalizing_spectrum_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15529
positive regulation of hydrolase activity	GO Biological Process Annotations 2025	1.0	null
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.08345
GAREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7601
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4106
BRD-K18888894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05215
STAT3	ENCODE Transcription Factor Targets	1.0	null
brown adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244232
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36115
GSE117730,GSE117732_0_v_1_apobec2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYNCRIP_OE_GDS3575_87_mouse_C57BL/6 mice	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K12853587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15792
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3666	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
Prostate adenocarcinoma_PRAD_TCGA-EJ-5517-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Obesity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.95
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.27797
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
icSARS CoV_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45647
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3439_KD_Ythdf2_SRP269726	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.56366
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35638
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79517375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09675
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61661
CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21608
GSE210667_3_v_2_rfx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
greatly	GeneRIF Biological Term Annotations	1.0	null
mtmr9	GeneRIF Biological Term Annotations	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0383
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888234
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0217
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88069191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74418
BRD-K47165178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30241
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46994278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06141
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880284
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1306
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30836
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22307
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49212
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72156149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01434
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.569603
GSE211474,GSE212779_8_v_5_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67636
PMC6962646-mmc2.xlsx-StemCell_Genesets_2018-POU5F1_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
DD-74-PJ26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235534
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39342915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17054
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9226
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841545
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.542309
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2194
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51325
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836333
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15169
hsa-miR-148a	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263658
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HO-1-N-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A549_S3I-201_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134732
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.76661
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69737
Galactose epimerase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78947
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9706
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322201
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	2.18219
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP1	ChEA Transcription Factor Targets	1.0	null
hsa-miR-130b-3p	MiRTarBase microRNA Targets	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94925
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9193
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TSPAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69264
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-Suppl_Table_6_DEG-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37748
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07852
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Dorsal aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845517
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.954
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78701
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.5301
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6759
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BFTC909	DepMap CRISPR Gene Dependency	1.0	2.17191
NCIH2023	CCLE Cell Line Gene Expression Profiles	1.0	1.78234
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6093-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
5903_NUP93_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	3.46102
PMC5550424-41467_2017_212_MOESM4_ESM.xlsx-Hematlas-Genesets-POU5F1_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4649-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.38456
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02018
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39555
H3K79me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05198
indices	GeneRIF Biological Term Annotations	1.0	null
HuO-3N1	GDSC Cell Line Gene Expression Profiles	1.0	1.42527
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45494
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.3696
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6493
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07141
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5908
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K38854468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54195
TAL1	ENCODE Transcription Factor Targets	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3355
Perturb_3299_KO_Bmpr1a_SRP116199	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.1579
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-BCL6_target_genes_in_N1-PEF1_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84279
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55471
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4761-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50386
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4893
BRD-K86491317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68381
BRD-K10135449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5933
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06728
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36862
BRD-K56826759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07358
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36170758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98189
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HEPG2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.13717
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36617
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.737876
TFAP2A-35110662-HEPM-HUMAN-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1667
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41202
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
LNZ308	DepMap CRISPR Gene Dependency	1.0	3.20913
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Ensembl_ID_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12716
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
BRD-K72213294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08764
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39615
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6045
CORL311	CCLE Cell Line Gene Expression Profiles	1.0	1.46514
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29415052_NVP-BGT226_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6_KO_GDS4375_532_mouse_Foxp3(+) Tregs	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65632
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Phosphatidylinositol 3-kinase complex, class IB	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.053
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22933
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-454	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
Perturb_3006_KD_FAP_SRP285807	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.59698
capan2	HPA Cell Line Gene Expression Profiles	-1.0	-0.888801
Sarcoma_SARC_TCGA-WK-A8XS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36658
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A97608543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13917
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nuclear envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
hsa-miR-301a	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40885
nucleus-vacuole junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10332
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18666
chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.1014
Transplanted Heart Complication_Myocardial tissue_GSE582	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.6724
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79561
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15385
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52675
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18941
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNMT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20442
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dephosphorylates	GeneRIF Biological Term Annotations	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23292
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44061
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51381
Perturb_6589_KO_Zfp708_SRP186171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.06565
HCC1937	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95523
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21608
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A693-06A-13R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5694
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997752
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980217
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11702_KD_MIR31HG_SRP051359	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05334
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20701
GUCY1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00485336
Perturb_11868_OE_Ezh2_SRP059688	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.15015
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KP2_PANCREAS	CCLE Cell Line Proteomics	1.0	4.48996
Perturb_14479_KD_WT1_SRP337713	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_8_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K70969650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08119
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39574
PLCXD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501136
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38343532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44356
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83139520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92368
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63363
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.25523
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14178
Birth Weight	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35866
PMC10055465-media-2.xlsx-ST15-Supplementary_Table_15_Bonferroni-significant_results_of_MAGMA_gene_based_association_analyses_EA_-_p_2_67e-06_0_05_18702_genes_AA_-_p_2_63e-06_0_05_18976_genes_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A76076412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02949
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.26185
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58789
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00158
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09342
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15802
BRD-K32471649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02317
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20803
BRD-K49159670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63771
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891274
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01683
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51739
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.945757
SARS-BatSRBD_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.31649
CCNYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33344
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6711
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05415
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23324
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08951
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DPEP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00532186
HDAC6_KO_GSE27896_383_mouse_Foxp3+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89376
ZNF831	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02555
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE80182_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75610411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13581
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
B3GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1588
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17614
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
phenylalanine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.828634
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5516-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NZM7	DepMap CRISPR Gene Dependency	1.0	2.05745
dephosphorylation	GO Biological Process Annotations 2015	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mantle zone of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14557
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	2.3133
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35938
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.610448
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.130822
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10256
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27083306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07022
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0639
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990846
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEx Heart 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-3.8179
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32347
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3267
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.334738
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13808
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
BRD-K31377965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89785
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042746
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14712
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00525
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.827923
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01746
BT-20	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54628
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K54925224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79636
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19573
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21842
hsa-miR-152	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
hsa-miR-19a	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06228
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03391
BRD-K99609051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62212
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6696
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17696
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05833
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28107
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931639
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4432	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-42-YI34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218533
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20079
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-1.48504
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21115
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.026823
outer SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873661
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.22508
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.42931
TMEM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13536
Liver Diseases	CTD Gene-Disease Associations	1.0	1.36361
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93551
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.79121
FMK	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.52
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
BRD-K40112492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09476
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4728
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.1306
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.798884
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03322
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00992
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.45191
PMC9038526-mmc1.xlsx-postCOVID_LPS_vs_healthy_L-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7099
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25769
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935369
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834599
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72231
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.919351
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.978809
hsa-miR-34c-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.354028
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02531
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876339
BRD-K91191855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79386
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835865
hsa-miR-144	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K30173809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0384
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29009
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.69358
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.670734
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977056
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205997
GSE133516_5_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25078
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45215
BRD-K31720099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23348
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.974814
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3638
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Symbol_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41138
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4071
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9132
2561_EIF4A3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.523921
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_unique_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21333
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.518962
NCIH1155	CCLE Cell Line Gene Expression Profiles	1.0	1.95114
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_11_v_3_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K04010869_PROSTAGLANDIN A1_HT115_6.0_h_1.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4776-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50603
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.00241
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PI Metabolism	Reactome Pathways 2024	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_TG101209_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174354
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOX17	ChEA Transcription Factor Targets	1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1341	CCLE Cell Line Gene Expression Profiles	1.0	1.46863
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.443
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0185
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884453
NSUN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04176
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A3OT-06A-23R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12663032-mmc7.xlsx-Supp_T6-Supplemental_Table_6_Dual_treated_vs_vehicle_treated_MSC_top_DEGs_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09296
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA_high-signal_selected_bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.891718
epilepsy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.555568
BRD-K11420482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1896
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94651
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU3F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75099
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased body size	MGI Mouse Phenotype Associations 2023	1.0	null
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08832
Pancreatic adenocarcinoma_PAAD_TCGA-F2-7276-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19289
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26351
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30016
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50904
hsa-miR-500a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285777
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
r5 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02993
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A97N-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03509
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
PMC11035615-41420_2024_1944_MOESM1_ESM.pdf-11-NFYA_NFYA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36923996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3971
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37484
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884081
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04434
ZNF263_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54802
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052314
BRD-K36190163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71824
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.837839
CUL3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54677
NCIH209	CCLE Cell Line Gene Expression Profiles	1.0	2.02187
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-34a	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
BRD-K66649343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07812
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
hsa-miR-548b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836242
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38861
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891837
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5253
MEF2A	ENCODE Transcription Factor Targets	1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATG2-ATG18 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.85
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72792
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCAS	CCLE Cell Line Gene Expression Profiles	-1.0	-2.18581
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4954
lhx8_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.182704
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04479
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15938
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3051
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.988219
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74978191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50207
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.541
hsa-miR-802	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
PMC4392212-gutjnl-2013-306620-s9.pdf-7-ZNF331_ZNF331	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40502
STUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1955
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10698156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13242
BRD-K45947503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03193
BRD-K16862492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12215
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
icSARS CoV_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.11889
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.8437
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56405136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52984
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1395	GDSC Cell Line Gene Expression Profiles	-1.0	-1.80863
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.7196
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47801291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99816
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10268
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2558
SHP77	CCLE Cell Line Gene Expression Profiles	1.0	1.35847
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DBIRD complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
phosphoric ester hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.68126
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	2.24804
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36875
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53636670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11287
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.391
VDR	ChEA Transcription Factor Targets	1.0	null
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81884775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12296
HT29	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74178
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5833
HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045245
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19253
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97653
RPS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16154
JMSU1_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	2.80653
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4552
GSE158834_11_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43017905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53757
AC-36-SY22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340185
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00032
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HB-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14322_KD_XPR1_SRP347870	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.38008
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FNDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48843
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.9162
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985154
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.72467
CNOT3	ChEA Transcription Factor Targets	1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Regorafenib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142388
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933787
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.837173
BRD-K62964360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99517
hsa-miR-21-5p	MiRTarBase microRNA Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
MKN7	GDSC Cell Line Gene Expression Profiles	-1.0	-1.82485
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4390530-NIHMS667786-supplement-1.xlsx-Sheet1-Supplementary_Table_2_Genes_closest_to_AR_induced_ASH2L_peaks_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
A549_Alendronate sodium trihydrate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165751
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K11227160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36106
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30138
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hereditary spastic paraplegia 23	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Foot sole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04427
BRD-K02959126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4747
Ovary	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.882073
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0873
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34291
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dehydration_Hypothalamus_GSE3110	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.74469
CEBPD_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-941	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HS294T	DepMap CRISPR Gene Dependency	1.0	5.32326
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Antennal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13075
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12911
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-148b	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0071
Premature aging_Skin fibroblast_GSE10123	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.84828
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90443
BRD-K75807882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0115
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.04101
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.873219
SRC_overexpression_277_GSE15161	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.78811
GSE239844_8_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
X31(H3N2)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.75336
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07609
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.01145
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ML-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20183527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20394
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K67665252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08046
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
independently	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72386335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78725
Synthesis of IP2, IP, and Ins in the cytosol	Reactome Pathways 2024	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65875972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34395
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
hMPV_6Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.43306
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8344
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07698
BRD-K96893659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52482
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167383
COLO800	DepMap CRISPR Gene Dependency	1.0	2.30962
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39119
NCI-H2126	GDSC Cell Line Gene Expression Profiles	-1.0	-1.4633
7424_RPAP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.694663
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70246
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8196-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-297	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01917
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25754
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49205
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
K562_Fedratinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0223051
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7876
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23629
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K64376499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35756
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832271
DEL	DepMap CRISPR Gene Dependency	1.0	6.14686
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-618	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866647
fto	GeneRIF Biological Term Annotations	1.0	null
BRD-A03997826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23664
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35308
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MS (Multiple Sclerosis)_B Cell Lymphocyte_GSE10064	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.10702
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CG-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fat pad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250301
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	2.18987
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45114
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898575
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838571
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K75186244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39856
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48965
GSE140936,GSE140938_2_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70378808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40736
HT1080	BioGPS Cell Line Gene Expression Profiles	1.0	1.03997
BRD-K58787433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36902
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07293
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.99807
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879392
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.929
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3378
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57575
HCC70	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.12964
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29475348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45839
BRD-K76114616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34081
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11051
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8796
K562_Tofacitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016561
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ET-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAPCA2B	CCLE Cell Line Gene CNV Profiles	1.0	1.46106
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-549	GDSC Cell Line Gene Expression Profiles	1.0	2.03723
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.962991
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF9_01_222	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6311
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320158
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5023
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86831
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866646
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.13041
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.59592
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.854
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4734-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.7475
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GB-96-WX99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243905
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.459953
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01683
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TE-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.642142
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46S-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78822
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69350688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65484
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71898
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3331
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPT20H_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32943037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24738
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58892
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22471908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37335
EWSR1_KD_GDS4962_468_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87853
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34875
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Golgi trans cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.033
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A3OU-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47848960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89477
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.6808
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46703
Esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883817
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.9533
BRD-K56759808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90666
BRD-K19580273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.524
16715129-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8239
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052522
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Amphisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
AKT1_knockdown_141_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.926898
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6744
HNRNPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03826
BRD-K40862705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24225
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PCI-6A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3215
GSE114232_8_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07906
syndrome	GeneRIF Biological Term Annotations	1.0	null
SIX5_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04778
Lung squamous cell carcinoma_LUSC_TCGA-34-A5IX-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6888
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_7_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.937519
GSE174701_5_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCAS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87448
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04772
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9323
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
n1e-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19889
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04884
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.994406
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.02432
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small_Intestine	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.14853
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45114
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.7766
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24372
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04853698_-666_SNUC4_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06065
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ah	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885097
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1827	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mad-Max complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.095
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40948
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.77288
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3938679-pone.0090284.s007.pdf-22-ZBTB20_ZBTB20	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09394
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.631121
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41919
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54478
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00102
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35808
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27885839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3357
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1204
A549_Givinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114388
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.894916
hsa-miR-3667-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCI-4B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55039
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K61517058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36434
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.954504
Ventricular hypertrophy_Myocardial tissue_GSE4678	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.89028
phosphatidylinositol-3,5-bisphosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
hsa-miR-4422	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127916_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7277
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00368
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.22277
hsa-miR-4295	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
required	GeneRIF Biological Term Annotations	1.0	null
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16873
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41015
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63152
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE238018_1_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO679	DepMap CRISPR Gene Dependency	1.0	4.08163
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13334
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5819186-13040_2018_163_MOESM3_ESM.xlsx-Lung-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.77717
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909477
EM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5327
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05534
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.21495
BRD-K12640996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47724
K562_PJ34_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159848
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41935
SNU61	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07122
hsa-miR-590-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
cellular process	GO Biological Process Annotations 2015	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62269
Perturb_2746_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39434
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894078
Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.3068
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.01624
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Egg white	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02323
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886796
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.897194
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057491
KIJK	DepMap CRISPR Gene Dependency	1.0	4.88409
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169571
SIN3A	ENCODE Transcription Factor Targets	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.34447
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02899
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49483
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K68305833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16311
BRD-K72787967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12114
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-BatSRBD_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.45364
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
20203266-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314831
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201952
hsa-miR-4325	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
metabolic process	GO Biological Process Annotations 2015	1.0	null
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.93979
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.104
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1789
MAP2K4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541978
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day7-C57BL6_None_GSE51386	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65483
BRD-K84924563_6-diazo-5-oxo-l-norleucine_NCIH508_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0161
hsa-miR-4719	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.74014
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74411
Weight Loss	CTD Gene-Disease Associations	1.0	1.11775
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08805
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21553
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1756
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28841
Perturb_1718_KO_Ripk3_SRP226420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.36914
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02532
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248874
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21301
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHRNB4_Deficiency_GDS2309_714_mouse_Brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76251351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67176
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43170571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38142
BRD-K74988798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2195
binding	GO Molecular Function Annotations 2015	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30821056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31627
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48207
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33505
Perturb_6572_KO_Gls_SRP338093	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.10428
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06497
GSE189172,GSE189173_2_v_0_traf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
BRD-K75206417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03835
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K47092271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26297
hsa-miR-1257	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971008
hsa-miR-4653-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.36194
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_PHA-680632_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119662
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07114
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K33495825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35269
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Waist circumference adjusted for body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
VPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51402
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34326
N1E-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
STK33	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Phosphatidylinositol signaling system	KEGG Pathways 2026	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0721
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04792
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39004
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes Mellitus	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-3613-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4103-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF4	ENCODE Transcription Factor Targets	1.0	null
GSE133087_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Phagophore assembly site membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.702
C15orf61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69661
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15992
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18673
KE39	DepMap CRISPR Gene Dependency	1.0	4.01838
KON	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00963
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874939
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906636
BRD-K09635314_-666_SW948_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRICD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17301
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8109-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226424
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
FNBP1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00521734
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02355
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.49737
Setleis syndrome_Skin fibroblast_GSE16524	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.92026
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DW-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-92a	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2723
K562_Vandetanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163336
CHP-212	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.86873
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858663
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01844
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein-containing complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3751
BRD-K55399138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0148
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.8961
GSK3A_KD_GDS4305_182_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Centronuclear myopathy X-linked	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.228
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2669
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Ellagic acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0220018
BRD-K43292469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14535
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203158_12_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00920341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56369
CC-84-JQ48_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246647
BRD-K21713052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47522
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37047
CEBPD	ENCODE Transcription Factor Targets	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197257_0_v_1_gpd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183101_0_v_1_hvcn1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5748-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
genetic	GeneRIF Biological Term Annotations	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.071912
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0212
BRD-K46313713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27075
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894078
PMC10274973-media-3.xlsx-ST18-Supplementary_Table_18_476_Bonferroni_significant_results_P_2_67_x_10-6_of_gene_based_association_analyses_H-MAGMA_dlPFC_cortical_neurons_for_sensation_seeking_factor_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0044
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-1.18448
BRD-K52989901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16419
BRD-K25517783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4341
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41372
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050967
EZH2	ENCODE Transcription Factor Targets	1.0	null
BRD-K15833017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55062
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.863753
MOLM13	CCLE Cell Line Gene CNV Profiles	1.0	1.63926
CNOT3-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050428
GSE201309_1_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943611
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K40276277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13595
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871959
BRD-K09487932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60253
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8781
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3323
BRD-K70751829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11462
BRD-K06576075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73511
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850009
KMRC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.391
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87717
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0775
SIMA	CCLE Cell Line Gene Expression Profiles	1.0	1.62812
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42847
JURLMK1	DepMap CRISPR Gene Dependency	1.0	4.51811
18081427-TableS7	GeneSigDB Published Gene Signatures	1.0	null
Tafamidis	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04329
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.39
SW1088	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1245
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08585
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6311
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23024
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31806725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49909
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.994364
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A03764094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00857
prediabetes syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.749237
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13251
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45114
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930606
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14631
hsa-miR-4773	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
K562_NVP-BSK805 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148331
RERF-GC-1B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27895
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.133913
ATF1	ENCODE Transcription Factor Targets	1.0	null
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.884223
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.43482
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.495
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5579
BRD-K13317726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44531
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PIGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31601
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of dephosphorylation	GO Biological Process Annotations 2025	1.0	null
Metabolic Syndrome X	HuGE Navigator Gene-Phenotype Associations	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244072_4_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211128_3_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oculocerebrorenal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
Hereditary spastic paraplegia 77	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41545
BRD-K60255752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11985
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-2467-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67016489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18107
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04576
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.72
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0863
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05285
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0198
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00339
K562_MLN8054_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170952
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08853
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIPK2_defectivemutant_17_GDS1793	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.4979
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
tremors	MGI Mouse Phenotype Associations 2023	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33604
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3338_GEMIN7_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.27832
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06134
SRF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5442-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWSR1	Hub Proteins Protein-Protein Interactions	1.0	null
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43555
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.08366
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1111
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98408
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
18440302-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.89614
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JARID1A-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59213
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO792	DepMap CRISPR Gene Dependency	1.0	7.71421
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81268
Synthesis of PIPs at the plasma membrane	Reactome Pathways 2024	1.0	null
Esophagus adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.572556
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02937
sensitivity	GeneRIF Biological Term Annotations	1.0	null
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22194
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12792
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0152
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5028
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9277
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16272
Movement Disorders	CTD Gene-Disease Associations	1.0	1.11325
caudal group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11857
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65749
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.10246
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02831
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70502
GSE210476_9_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03241
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6238
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7679
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62492257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2907
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03553
BRD-A94659883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20463
BRD-K85066228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97927
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969206
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.905053
ELF5	ChEA Transcription Factor Targets	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_8-Supplementary_Table_8_ETV6-repressed_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00829
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fruit consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.804576
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-130b	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432851
hsa-miR-19b	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0834
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of phospholipid metabolic process	GO Biological Process Annotations 2023	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.46637
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K15387690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50804
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10274973-media-3.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20578
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
chr8_11285116_T_C_b38	GTEx eQTL 2025	1.0	3.88172
KP4_PANCREAS	CCLE Cell Line Proteomics	1.0	2.58473
ES7	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.00197
18593951-TableS2	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-3609	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-181b	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2493
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4765-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68257831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0086
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53423
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.1037
BRD-K16432886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73138
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59115
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.03699
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18904
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0213
SW1116	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38824
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35936801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56621
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69517
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11128
KLE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38685
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31151
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.096028
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914969
GSE236511_1_v_0_ngfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05825
BRD-K53186055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19741
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chrysophanic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01076
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927268
hsa-miR-1286	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74786
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
1200_KNL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.549582
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863321
AR-21909140-LNCAP PROSTATE CANCER CELL LINES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.89892
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.31506
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871352
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8157
LIVF001-028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05613
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84971
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AQP11_Deficiency_GDS3395_578_mouse_Kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Acquired metabolic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.95
SP4	ENCODE Transcription Factor Targets	1.0	null
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Fibrosis	CTD Gene-Disease Associations	1.0	1.32637
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.751
Sarcoma_SARC_TCGA-DX-A1KU-01A-32R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149395
BRD-K21935128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19548
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.4076
BRD-K05119275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89412
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59076
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-45_ChIP-Seq_H3K9me1_2_AR_differential_expression_upon_KDM3A_and_AR_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1581	DepMap CRISPR Gene Dependency	1.0	2.03188
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34123
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17543
Osteopathia striata with cranial sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SYNCRIP_OE_GDS1886_83_human_THP-1 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE211128_7_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.404
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0062
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14558
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.06588
GSE147626_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.167
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9785
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0617
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHL-1	GDSC Cell Line Gene Expression Profiles	1.0	1.90026
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFAP418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06612
hsa-miR-486-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5844-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23629
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95508
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.999882
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951772
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52452
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896921
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4278	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27218
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29782
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2596
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11841
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0283
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840785
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13251
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00907
BRD-K40001806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00848
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02337
BRD-K73680186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2114
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891551
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03689
blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K94347944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18616
BRD-K13817284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11746
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0965
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71147
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01064
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Huntington's Disease_Brain_GSE3621	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.58246
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02875
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45114
Prostate adenocarcinoma_PRAD_TCGA-EJ-5515-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
KDM1A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.043
Entorhinal area, medial part, dorsal zone, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09979
ZFX-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05435
Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6971
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2122	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852975
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26696
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046405
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18971
PML	ENCODE Transcription Factor Targets	1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.380027
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4344-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00321
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24487
2276_DNAJA2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.803781
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946409
MCF7	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.21193
phosphatidylinositol dephosphorylation	GO Biological Process Annotations 2025	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02852
SNU620	CCLE Cell Line Gene CNV Profiles	1.0	1.40367
insulin	GeneRIF Biological Term Annotations	1.0	null
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4831
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17968
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.15883
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149377
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.96383
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2368
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K46161579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05485
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251027
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MB-53-WO35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217521
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
K562_Glesatinib(MGCD265)_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148632
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.28253
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
obesity	GAD Gene-Disease Associations	1.0	null
mantle zone of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37317
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1269
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.02157
8p23 1 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
ZFP281-27345836-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-330-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983476
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9002
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.26942
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-50-6595-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41705
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90867
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.17235
BRD-K79228133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77644
MTA3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3	ENCODE Transcription Factor Targets	1.0	null
r4 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05825
BRD-K22718400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43051
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08601
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65127
K562_PD173074_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150057
hsa-miR-548t	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
BRD-K19036695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35881
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18568
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.1882
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27246
glucose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.368518
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31588
BRD-K00530465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35176
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093327
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0555
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60701773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53416
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52315
Metabolism	Reactome Pathways 2024	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72009
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42348
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940489
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.224
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.951409
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H209	GDSC Cell Line Gene Expression Profiles	1.0	1.45652
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07225
MEG01	CCLE Cell Line Gene CNV Profiles	1.0	1.53354
GSE193993_5_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6971
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846482
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76748254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24153
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Costunolide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169142
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bolting stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23556
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SAOS2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.58506
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G-MEL	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.82146
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4R8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041011
hsa-miR-2114	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95692
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.78228
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT549	CCLE Cell Line Gene CNV Profiles	1.0	1.58204
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.08462
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.639382
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.884016
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221506
PMC3435504-msb201237-s2.xls-Supp_Table_4a-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
cone-rod dystrophy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.1101
Perturb_6262_KD_NDP_SRP188348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.56757
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1074
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A47B-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.23358
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921886
NEK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0041654
U87	BioGPS Cell Line Gene Expression Profiles	1.0	0.910365
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52577
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971852
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211128_9_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2079
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04911
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal tooth morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K67586245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77872
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4973
H4K5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0273
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75979
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16423
15543619-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7755
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04207
STAT5A	ENCODE Transcription Factor Targets	1.0	null
NET1_KD_GDS4196_436_human_AGS - gastric adenocarcinoma cells - (63 shRNA Knock-Down)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21081
functions	GeneRIF Biological Term Annotations	1.0	null
BRD-K26079895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0831
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K47895166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82427
Perturb_10679_KD|Mut_Cux1|Nras_SRP292900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.37194
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38807
ESR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00592652
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19821
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCMV_24Hour-AG_pretreatment_20173022_GSE17948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.544
6847_PSMA7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.531981
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_6_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K90999585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34492
GSE138945,GSE138947_0_v_1_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43862
BRD-K27256143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30524
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1744
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19377
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3674	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
STAT1	ENCODE Transcription Factor Targets	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.849115
19305503-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09825
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
PMC8045971-Table_3.xlsx-vs_LPS_ctrl-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
20368555-TS-1	GeneSigDB Published Gene Signatures	1.0	null
TEAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8819
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6998-01A-23R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9904
PMC10940914-mmc4.docx-0-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
SYK_druginhibition_288_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.56063
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.076079
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.900707
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927186
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
AKT1_knockout_215_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.44245
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Perturb_11704_KD_MIR31HG_SRP051359	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.4888
BRD-K63711467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4645
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
HUPT4	DepMap CRISPR Gene Dependency	1.0	8.6266
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98239
TBX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15785
HUP-T4	COSMIC Cell Line Gene CNV Profiles	1.0	2.14311
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32141
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
singlenucleotide	GeneRIF Biological Term Annotations	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10935
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	3.76731
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950819
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53042
ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.524704
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5766
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04535
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60694
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30491662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00033
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.4
PAX5	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.14057
BRD-K39813155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0207
BRD-K73573090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57298
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2143
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6917
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37645
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of hydrolase activity	GO Biological Process Annotations 2023	1.0	null
BRD-K31820800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72338
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.8389
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898365
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC2A4	Hub Proteins Protein-Protein Interactions	1.0	null
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54283
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247858
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33557
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05539
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04465
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.232888
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
BRD-K32983008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22709
BRD-K86912219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41349
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
BRD-K46308702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14968
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5733
BRD-K00347903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10313
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22753
BRD-K06519744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47968
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3627
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923369
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5791
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05377
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2037
RUNX2_01_62	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61781
Perturb_4538_KO_Mtf2_SRP103933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.972
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-23c	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03369
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
SJSA1	CCLE Cell Line Gene Expression Profiles	1.0	1.64662
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6894
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04358
BRD-K32699895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21791
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
t64-ovaries_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.88464
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1531
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08805
BRD-K59518944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01533
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCAM1	MSigDB Cancer Gene Co-expression Modules	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45466
BRD-K99681648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19536
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01317
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Polycystic Ovary Syndrome_Adipose tissue_GSE5090	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.18295
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.7046
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4299
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38685
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
507_ARL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.61968
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2975
BRD-K29707171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45421
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92927
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39678
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906831
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.928781
regulation of macromolecule metabolic process	GO Biological Process Annotations 2023	1.0	null
NEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24733
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.437972
FLI1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05967
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
BA-46-YF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214253
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7996
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56025
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9827
BRD-K78098006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16713
SRF	ENCODE Transcription Factor Targets	1.0	null
BRD-A07195938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02484
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389379
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
non-syndromic intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
Retinal vascular caliber	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93405
hsa-miR-1972	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
hsa-miR-34a-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91597
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03584
SLC35C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06207
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6299
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70697
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17673
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1969
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40312
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4728
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12716
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Restless legs syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.391
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3231
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.709
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36515664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62113
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86371068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28659
Barrett's esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861976
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2128
hsa-miR-181c	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
Perturb_2747_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
K562_Costunolide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159817
BRD-K53612850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81135
CIDEC_KO_GDS3776_552_mouse_Brown and white adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02932
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31842
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47963
Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hydrolase activity, acting on ester bonds	GO Molecular Function Annotations 2015	1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63386
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24554824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20127
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.43207
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hereditary spastic paraplegia 61	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
CTCF_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR5	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.874642
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30809
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901047
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
GSE119345_2_v_4_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885849
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Phosphatidylinositol 3-kinase complex, class IA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53901855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18997
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838157
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07713
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34026318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02061
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31924
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4313
hsa-miR-338-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K73176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09911
BRD-K51791049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65169
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K01329192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6585
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22128
hsa-miR-522	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
BRD-K40565784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03204
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K29673910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71664
BRD-K44062658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8673
PMC7782698-41467_2020_20367_MOESM9_ESM.xlsx-Student_s_t-test_BP1_ILK_GFP-Gene_names_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z3-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.2511
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897285
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
K562_Disulfiram_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167429
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.105862
NR4A1_01_174	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.81333
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40256
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A388	COSMIC Cell Line Gene Mutation Profiles	1.0	null
doxorubicin_homo sapiens_gpl550_gse1647	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916213
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKT1_knockout_214_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.46169
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Protein-tyrosine phosphatase-like	InterPro Predicted Protein Domain Annotations	1.0	null
IHH4	DepMap CRISPR Gene Dependency	1.0	6.78482
BRD-K27172015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25876
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05388
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.07094
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54569
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71178
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.941
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161170,GSE161268_0_v_2_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-885-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15416
BRD-K77241556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09987
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894078
PFKL_OE_GDS1980_203_mouse_dermal fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-A56909893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07761
16289389-TableS1	GeneSigDB Published Gene Signatures	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13948
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909384
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.04923
GNG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66535
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10411
BRD-K69668461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44128
DANG	CCLE Cell Line Gene Expression Profiles	1.0	2.72101
negative regulation of cellular catabolic process	GO Biological Process Annotations 2023	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15614
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1253	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74477
hsa-miR-4774-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
HCMV_24Hour_20173022_GSE17948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.84149
Cystic Fibrosis_Pancreas_GSE769	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.03852
BRD-K39584933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43146
BRD-K37014934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71365
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.62
BRD-K31336762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26548
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.18481
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06752
LU99	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38111
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67508052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.028
Perturb_7999_KO_Wwtr1/Yap1_SRP265287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.89858
CD164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02003
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35705
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_2_ZZZ3_occupied_genes-ATAC1_bound_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
Hereditary spastic paraplegia 75	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951049
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.6277
hsa-miR-23a	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19999
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
OAW-28	GDSC Cell Line Gene Expression Profiles	-1.0	-1.84132
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05035
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2028
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36527
hsa-miR-149	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45114
NFIC	ENCODE Transcription Factor Targets	1.0	null
Protein phosphatase 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-43-KF54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247614
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1467
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4302
ZNF445	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67843
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961942
BRD-K67597437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47466
phosphatidylinositol bisphosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K07351191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45934
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.909197
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955221
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	1.29074
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834717
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915827
HCC1143_BREAST	CCLE Cell Line Proteomics	1.0	4.48996
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79704
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK14_knockdown_139_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.18825
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59576
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46566
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.84212
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43839
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8043
BRD-K89967940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49981
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7054
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7589
PMC10961392__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2645
BRD-K29298614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75217
obesity	GeneRIF Biological Term Annotations	1.0	null
Waist-hip index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
Metabolism of lipids	Reactome Pathways 2024	1.0	null
tcf3_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.018313
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960984
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46107
GATA3	ENCODE Transcription Factor Targets	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.512
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTMR6	Pathway Commons Protein-Protein Interactions	1.0	null
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of autophagy	GO Biological Process Annotations 2023	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
TGFBR2_knockout_293_GSE46211	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.64227
Spinal Muscular Atrophy, Infantile_CNS - Spinal Cord (MMHCC)_GSE3075	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.87203
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45828
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0635
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39768
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24773
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36449
HHLA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490878
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7297
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
influence	GeneRIF Biological Term Annotations	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMCB	CCLE Cell Line Gene Expression Profiles	1.0	1.42497
CW2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12497
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5827
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.26847
white adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24676
Myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053452
EF-33-QP63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220363
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K81522725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01748
SIX5	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-603	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4789-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07898
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41051
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993174
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31999
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IB-30-KN41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250098
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Gastric	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.05378
hsa-miR-545	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ASXL1	ChEA Transcription Factor Targets	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207787_1_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.915482
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937573
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.537
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.79332
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852156
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K17059629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30367
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.984
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.346
NCI-H1836	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.0665
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of phospholipid metabolic process	GO Biological Process Annotations 2025	1.0	null
BRD-K23637241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0376
hsa-miR-3941	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20202
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75738997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68054
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12121
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1651
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Patupilone_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134591
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.977086
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853634
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236763
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38619
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66329
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.22793
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34922
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46722
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1982
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ERBB4-ERBB4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
PMC9314343-41467_2022_31892_MOESM8_ESM.xlsx-FigS7d-CTCF_in_promoter_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_52_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11282
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928681
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-582-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954206
ARPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63201
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3215
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.27131
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04152
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21962
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36224
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.0589
hsa-miR-4448	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
CAL851	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49102
Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_10_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOS	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.36526
Kleefstra syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.17881
SOX2	ChEA Transcription Factor Targets	1.0	null
GSE158834_11_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K65086352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04256
BRD-K74150320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27935
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
731_B3GNTL1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.545714
Adrenocortical carcinoma_ACC_TCGA-OR-A5JR-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.910229
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83519
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15327
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56518
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phosphatidylinositol monophosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K95943192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05374
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210662_3_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10082046-41467_2023_37049_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_Genes_upregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55899
KRT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5721
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.03827
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4136
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836008
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060389
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30831
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914623
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.9233
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5448
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873011
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27147269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06353
QPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26462
GSE163240_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51788
BRD-K24143478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16614
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7794
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.28868
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.19607
hsa-miR-23b	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
LGLL - Large granular lymphocytic leukemia_Peripheral blood mononuclear cell_GSE10631	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53007
Lung squamous cell carcinoma_LUSC_TCGA-92-8065-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866365
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Macropinocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.557
EC-47-EO60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295797
K562_S3I-201_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171499
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944402
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.52
6632_PPIL4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.585738
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3372
Acute Myeloid Leukemia_LAML_TCGA-AB-2863-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.861438
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49948
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18635665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3087
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7086-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.11557
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08731
adipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05091
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887285
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4609150-13073_2015_228_MOESM2_ESM.xlsx-TP53-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1617
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50998
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04349
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45114
phosphatase binding	GO Molecular Function Annotations 2023	1.0	null
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202964
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	3.01769
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02179
BRD-K26708780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60413
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8962
RMUGS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64132
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCL22	DepMap CRISPR Gene Dependency	1.0	2.29565
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65741216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04513
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31504
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.77231
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.097
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.13101
YY1-26981420-C2C12-MOUSE-MUSCLE	ChEA Transcription Factor Targets 2022	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04267
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.919673
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55096
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.97814
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0352
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345875
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850633
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938455
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-148a-3p	MiRTarBase microRNA Targets	1.0	null
Congenital structural myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.08
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-421_ChIP-Seq_H3K9me1_2_AR_differential_expression_upon_KDM3A_or_AR_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Squamous cell carcinoma of mouth_Oropharynx Epithelium_GSE3524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.90384
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918534
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.276
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20062
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22827
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051978
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15411
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2021
ZBTB33_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.93323
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986183
BRD-K31834149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66713
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051979
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19661
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17536
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85405
SUM 159PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853952
KDM5A	ENCODE Transcription Factor Targets	1.0	null
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41485
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13398
hsa-miR-449a	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895469
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890205
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Common_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96549
TSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02025
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891619
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09986
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464818
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
atracurium besilate-1824	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAL851	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77087
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
Perturb_7447_OE_MIR941_SRP096893	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.56728
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
protein stabilization	GO Biological Process Annotations 2023	1.0	null
Phospholipid metabolism	Reactome Pathways 2024	1.0	null
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45271289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05767
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
3504_GPN3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.539062
GSE217452_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42037
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K46149455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60008
Prostate adenocarcinoma_PRAD_TCGA-EJ-7317-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22610244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06465
GSE254649_3_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.093
positive regulation of phosphatase activity	GO Biological Process Annotations 2025	1.0	null
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29431
JJN3	CCLE Cell Line Gene CNV Profiles	1.0	1.61467
20460173-ImmPortCD40LvsControl	GeneSigDB Published Gene Signatures	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.428365
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19979
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839977
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05545
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
PARK7_KD_GDS3750_2_human_SH-SY5Y	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.40815
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0708
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19383
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3252
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25359
BRD-K64862097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68798
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-1526-SM-4BRV4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27268
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33987
hsa-miR-494	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.913981
Perturb_6216_KO_Mef2c_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962665
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.838732
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.32
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916094
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20044
BRD-K00377328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37192
K029AX	DepMap CRISPR Gene Dependency	1.0	7.08665
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977388
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.62
MAGEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31725
UBTF	ENCODE Transcription Factor Targets	1.0	null
BRD-K70511574_sunitinib_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15794
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42758
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
NB10	GDSC Cell Line Gene Expression Profiles	1.0	2.01835
NFE2	ENCODE Transcription Factor Targets	1.0	null
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7463
GSE200099_2_v_0_honokiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70148902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86568
WSUDLCL2	CCLE Cell Line Gene CNV Profiles	1.0	1.45513
SPI1	ChEA Transcription Factor Targets	1.0	null
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986051
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5551
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925516
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AKT1_knockout_211_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.47158
ELF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997089
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34524418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21298
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ChIP_CNOT3_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K37253987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14049
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20879770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63206
BRD-K96624721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76791
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00456
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.936584
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GJ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10893
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91820608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26651
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957194
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.73427
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982849
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TX-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190186,GSE190188_8_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K01297681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10391
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43975
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45677596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73982
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1776
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3969
DICER1_Deficiency_GDS3685_518_mouse_Hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03459
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19656
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.792426
ZMYM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33856
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGBC11TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-3.99887
GSE178340_5_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K96133500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08632
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S15-Table_S15_List_of_the_genes_commonly_regulated_by_AhR_and_OVOL1_in_TSB-treated_NHEKs_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37218
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42265
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BCL3	ENCODE Transcription Factor Targets	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49570068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87226
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
HEPG2	DepMap CRISPR Gene Dependency	1.0	5.3437
BRD-K82919339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20225
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4236
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K37151525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14778
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40921
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4885
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51916
BRD-K40248932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30781
FSP27_KO_GDS3768_514_mouse_White adipose tissue  (WAT)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r7 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57373
Hereditary spastic paraplegia 5A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70148257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17924
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MHH-NB-11	GDSC Cell Line Gene Expression Profiles	1.0	1.51255
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909901
K562_Veliparib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0272903
HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RB_Deficiency_GDS2757_644_mouse_Embryonic livers (day 12.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824166
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39573
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04727
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12654
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9912
7513_RPS24_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.537755
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044349
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	1.44024
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC2866657-pone.0010547.s003.xls-ERG_corr-Genes_correlated_anticorrelated_to_ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of autophagy	GO Biological Process Annotations 2025	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23134
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
4-PPBP	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30439
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
Ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.25
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53836
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39765
BRD-K87259147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48633
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH322	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47232
KCL22	CCLE Cell Line Gene CNV Profiles	1.0	1.9365
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886463
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10819
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874772
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Schizophrenia_CNS - Brain - Cerebellum (MMHCC)_GSE4036	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.59059
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BECN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00432069
BRD-K00350773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36205
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62758
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-526b	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
SKBR3	DepMap CRISPR Gene Dependency	1.0	4.46496
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14545
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82162
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32253
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97623
Phosphoinositides metabolism	WikiPathways Pathways 2024	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.119
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71847
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929755
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.44899
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AC-97-KP88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242138
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05776
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29829
BRD-K30240666_CLEMASTINE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37467
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63271
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54506
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06802
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89040444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25047
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17685
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00066
BRD-K38604123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34255
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76817
FLI1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL2136 (ROCK1)	NURSA Protein Complexes	1.0	null
GTEx BloodVessel 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-9.11616
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.47318
BRD-K22748970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3897
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2176
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
positive regulation of dephosphorylation	GO Biological Process Annotations 2025	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24258
JHH4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62794
BRD-K58232861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81832
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49711
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228124
BRD-K92632379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30143
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36423
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.66054
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08353229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74097
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
3502_GPN1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.637038
Teratogenesis	CTD Gene-Disease Associations	1.0	1.03641
hsa-miR-142-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20742
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.95008
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877863
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029965
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
1872_CRIM1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.672982
COLO684	CCLE Cell Line Gene CNV Profiles	1.0	1.68782
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86108
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257613
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A510-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.18226
PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.848
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70597
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.022
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902987
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13926
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5733
BRD-A91823394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31201
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26195
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Alendronate sodium trihydrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161209
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.860712
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K83135157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.108
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2179
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5846
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	0.948536
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73598
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10514
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19018
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61603
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19682
K562_BMS-536924_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014097
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00898
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973424
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85912
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47775
HCC1937_BREAST	CCLE Cell Line Proteomics	1.0	3.71506
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32815
smooth muscle	HPA Tissue Gene Expression Profiles	1.0	0.998258
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K40266835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41765
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.861346
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143643,GSE143644_2_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
tolerance	GeneRIF Biological Term Annotations	1.0	null
BRD-K32577562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.13078
EIF4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12553
A549_Busulfan_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150935
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060613
SKNMC	CCLE Cell Line Gene Expression Profiles	1.0	1.41943
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21323
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.9432
leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06687
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49279
MAZ	ENCODE Transcription Factor Targets	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54724
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EMILIN1	Pathway Commons Protein-Protein Interactions	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8586238-41467_2021_26788_MOESM6_ESM.xlsx-S2A_CDE_genes-S2A_CDE_-_genes_of_the_two_CCD_genes_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.39516
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_11_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28266
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91014
EGR1	ENCODE Transcription Factor Targets	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01083922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68448
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8164
GSK3B_KD_GDS4305_181_human_MOLM-14 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.49281
hsa-miR-363	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361955
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13953
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11263707-41419_2024_6896_MOESM4_ESM.pdf-4-ADNP_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223609,GSE223610_0_v_2_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46968
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944031
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924161
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung Diseases	CTD Gene-Disease Associations	1.0	1.04611
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90060707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20269
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEx Heart 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-3.1135
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
9886_XAB2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.544014
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70584304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55859
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2222
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53858
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
klf7_17123745_olfactory_epithelium_lof_mouse_gpl1261_gds2069	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-2.64333
all	GWASdb SNP-Phenotype Associations	1.0	0.029928
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
EWSR1	ChEA Transcription Factor Targets	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
TPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35443
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12522
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
phosphatase activity	GO Molecular Function Annotations 2015	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08214
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24574
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86992
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835877
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vorinostat_homo sapiens_gpl571_gse18544	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU61	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41243
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846666
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45414
BRD-K18211442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23077
SKMEL28	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.875738
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3193
hsa-miR-4717-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3669
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.4857
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.97298
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4295
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.959503
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838926
regulation of phosphatase activity	GO Biological Process Annotations 2023	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4707
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.986586
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.944977
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9154
ATF3_01_33	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59452
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4386
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65313
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28166
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980654
obesity	GWASdb SNP-Disease Associations	1.0	1.30639
KP-N-YS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12857
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
GSE236502_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04398
ARH77	DepMap CRISPR Gene Dependency	1.0	2.51806
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01216
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12669
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.902858
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25184
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051774
Esophageal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047652
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62783
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
A549_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143338
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1869	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48706
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0576
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.378
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5025
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04275
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860497
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prediabetes Syndrome	DisGeNET Gene-Disease Associations	1.0	null
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19305
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79976
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08125
Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05652
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.14801
BRD-K67725403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53661
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX3_01_359	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58841
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900012
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GPR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64054
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88072
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983995
Lung squamous cell carcinoma_LUSC_TCGA-34-5929-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.1806
BRD-K31783598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04566
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4265
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246273
K562_AT9283_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160427
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1347
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3669
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24216
CTBP2	ENCODE Transcription Factor Targets	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18843
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03953354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35685
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79918
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22334
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.10746
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922567
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53722
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00017
Perturb_15398_KD_KIF15_SRP262423	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.66655
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01766
phosphate-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Colorectaladenocarcinoma	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.62848
hsa-miR-4511	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J7-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.21243
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.943107
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.925514
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.882294
NB4	DepMap CRISPR Gene Dependency	1.0	6.46254
cell leading edge	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.295119
tcof1_15522210_neuroblastoma_gof_mouse_gpl339_gds998	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.493891
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9967
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15719
BRD-K78866630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50135
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K54111001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29719
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00647
15902281-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27266
IALM_LUNG	CCLE Cell Line Proteomics	1.0	11.3592
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895433
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36006
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01636
hsa-miR-3618	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081918
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
NCIH747_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.25521
FOXP3	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T0-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47237224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1069
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-684	GDSC Cell Line Gene Expression Profiles	1.0	1.78987
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826397
Lamin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
hsa-miR-210	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
hsa-miR-181d	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
BRD-K21635957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41827
Lung adenocarcinoma_LUAD_TCGA-78-7536-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-202	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02809
BRD-K52956006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06232
MMAC-SF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68298468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26978
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21332
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_38_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21543
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_11_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4672	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
SMC3	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.926565
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50531
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.60504
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94456
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7443
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31668
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78496
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51312
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0694
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTMR8	Pathway Commons Protein-Protein Interactions	1.0	null
ABHD16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83061
TK10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978344
GSK3A_knockdown_203_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.3751
BRD-K08154407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27241
T-cell chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190534,GSE190536_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51242
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0568
L428	CCLE Cell Line Gene Expression Profiles	1.0	1.56742
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292793
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K44007425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15334
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8189
LC4-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Essential hypertension (time to event)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67087027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01136
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2464
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.3937
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10667
GSE112763,GSE112767_4_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864256
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72388
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56717
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908044
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01552
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-VN-1203-2004(H5N1)_Day7-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.70088
protein phosphatase binding	GO Molecular Function Annotations 2025	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPRED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02636
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847428
ERBB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74279
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13743
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AGS	CCLE Cell Line Gene CNV Profiles	-1.0	-2.57855
hsa-miR-513a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
HDAC6_KO_GDS4375_372_mouse_CD4+CD25+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K65780164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05038
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06851
APLP2_KO_GDS4414_371_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1032
protein phosphatase binding	GO Molecular Function Annotations 2023	1.0	null
GSE229468,GSE229471_0_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2727
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01281
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22931
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19724
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Filgotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185233
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08312
Malignant mesothelioma of pleura_Pleura_GSE2549	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.80292
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968585
BRD-K51666223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12357
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49414
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC1171	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80001
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1071-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11088
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26908
Cef cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.145
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04456
REST	ChEA Transcription Factor Targets	1.0	null
H9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24746
hsa-miR-4727-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58657
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999225
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1683
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834717
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53129
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tubulobulbar complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00823
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7253-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNMC	CCLE Cell Line Gene CNV Profiles	1.0	2.07047
KYSE140	DepMap CRISPR Gene Dependency	1.0	2.24623
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824897
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.496
BRD-K35727000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36043
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20668
Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T84	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62763
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.768266
Brain Lower Grade Glioma_LGG_TCGA-HW-7493-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXC9	ChEA Transcription Factor Targets	1.0	null
HCMV_24Hour-Infection+PP2_21084488_GSE24238	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.2755
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24517
Prostate adenocarcinoma_PRAD_TCGA-CH-5752-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hereditary spastic paraplegia 73	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.23913
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-335	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15491
BRD-K30103771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12457
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02447
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05193
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.934955
BRD-A81407814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34424
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25249
E2F1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.231482
hsf1_17216044_hela_lof_human_gpl571_gds1733	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.191197
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78066
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10947
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51453
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
K562_Motesanib Diphosphate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161296
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31183
AE-21-BF25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230935
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043289
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13569
negative regulation of catabolic process	GO Biological Process Annotations 2025	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27901
Acute Myeloid Leukemia_LAML_TCGA-AB-2842-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	3.05929
Bmi1_Deficiency_GDS4816_323_mouse_Primary lung cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
u266	HPA Cell Line Gene Expression Profiles	-1.0	-1.32861
ZNF57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57332
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04901
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25811
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35692
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1I2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00465843
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03707
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.89614
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12804
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.14288
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.960393
Perturb_11696_Mut|KD_HRAS_SRP278399	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41768
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7014
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4268
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55855103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06494
Perturb_12881_KO_Mof_SRP073926	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.06459
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8759
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1356
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55824
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Supplementary_Data_7_ZZZ3_occupied_genes_and_overlaps_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
ELK4_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967264
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33065
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6267
SIMA	GDSC Cell Line Gene Expression Profiles	1.0	1.98822
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8691
K562_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143568
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46755
Protozoan Infection_Intestinal Epithelium_GSE2077	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.76189
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03069
MAX	ENCODE Transcription Factor Targets	1.0	null
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10387
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16481
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myotubularin-like phosphatase domain	InterPro Predicted Protein Domain Annotations	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09875
CCDC74A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0673
PMC11030494-media-2.xlsx-ST12-Unnamed_9_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BICR16	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_160_KD_Ago2_SRP259987	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.18316
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.39474
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05342
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Carmofur_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125834
Perturb_5009_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.36625
BRD-K59657378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62345
phospholipid dephosphorylation	GO Biological Process Annotations 2025	1.0	null
hsa-miR-4251	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
GSE158834_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0132
CTCF_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX39B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00622896
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-759	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40098
Sarcoma_SARC_TCGA-WK-A8XZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53481
BRD-K69408624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42183
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8753
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.01089
SHP-77	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.49656
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Bernard-Soulier syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044527
GSE148657_3_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LIVF001-013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13711
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51112
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYBL2_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00208
4314_KDELR1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.67689
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40610042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09138
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
Extraversion (Psychology)	DisGeNET Gene-Phenotype Associations	1.0	null
Lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5338
BRD-K44537081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43366
risk	GeneRIF Biological Term Annotations	1.0	null
fluoxetine_mus musculus_gpl1261_gse35761	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84493
BRD-K73126584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84561
SIN3B	ChEA Transcription Factor Targets	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20847
MM370	DepMap CRISPR Gene Dependency	1.0	8.25894
NKX3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07962
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
6793_PRPF31_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.627316
CDK8_knockdown_88_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.84031
phosphatase binding	GO Molecular Function Annotations 2025	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02134
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.06233
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9036
Perturb_1603_KO_Tlr4_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.44206
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_420_KD_FOXM1_SRP239534	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22402
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A681-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
seizures	MGI Mouse Phenotype Associations 2023	1.0	null
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.826688
hsa-miR-3685	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057966
AR-21909140-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945039
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5421
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22228
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936637
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5110-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Phagocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.885
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03986
KURAMOCHI	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44814
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
17009876-tableS3a	GeneSigDB Published Gene Signatures	1.0	null
BRD-K53326976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10197
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06315
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37951
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6527
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43082
WM88	DepMap CRISPR Gene Dependency	1.0	7.64052
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3055
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20989
Lung squamous cell carcinoma_LUSC_TCGA-66-2773-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELA_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	6.07282
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03725
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26001
BRD-K90480740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05188
GM1600	BioGPS Cell Line Gene Expression Profiles	1.0	1.26729
BRD-K18623962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02435
Generalized epilepsy with febrile seizures plus 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.356
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.09927
TRIM28_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6657958-pgen.1008250.s015.xlsx-ETS1_siRNA-Unnamed_0_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00692
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r6 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14663
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	1.0	1.69134
Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1008	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.24517
Spinal Cord Injury_CNS - Spinal Cord (MMHCC)_GSE16710	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.60104
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.91639
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
icSARS CoV_30Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.37215
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99638698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12159
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35777
IE-02-TR35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376708
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46613
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Veliparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139908
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88807
TAF1	ENCODE Transcription Factor Targets	1.0	null
GSE146074_0_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.131
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.33636
BRD-K95900761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30426
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068678
Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.97224
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824594
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CGTH-W-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7302-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HHIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00911
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54555
Lung squamous cell carcinoma_LUSC_TCGA-18-3409-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSS	CCLE Cell Line Gene Expression Profiles	1.0	1.45668
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8172-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0327
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059991
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349562
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K81082552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73284
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26908
Polycystic kidney disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL-AF4_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
ECC10	CCLE Cell Line Gene Expression Profiles	1.0	2.03872
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SW1116	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76126
regulation of macroautophagy	GO Biological Process Annotations 2025	1.0	null
BRD-K13941175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10313
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24748087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03694
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCLAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Charcot-Marie-Tooth disease type 4B1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.987
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6432
Fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.524
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.53077
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K23075656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08147
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92315
Synthesis of PIPs at the late endosome membrane	Reactome Pathways 2024	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.5768
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	1.62808
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250182
BRD-K73539077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20605
GSE131649_6_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SETDB1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50262
BRD-K19103580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01808
BRD-K33510044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16687
ONECUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08645
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30263
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920854
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TRIM28	ChEA Transcription Factor Targets	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4154
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02427
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K20525312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84238
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_7day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.63014
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78287
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24221
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2307
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1408_CDC5L_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.604943
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31822
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38687
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3647
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927185
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21673
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.957364
TMEM82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73899
LAMA84	CCLE Cell Line Gene CNV Profiles	1.0	1.3787
SU-DHL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10882188-ADB-29-e13365-s002.xlsx-ST18-Unnamed_8_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51435
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR7	Pathway Commons Protein-Protein Interactions	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NTERA-2_CL_D1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6035
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01772
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Posterior cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4605
phosphatidylinositol-3-phosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
CTH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39665
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K82868643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07318
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03287885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48087
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23556
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94746
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050999
BRD-K55164454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2696
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65598127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12211
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50098
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95477
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13388_KD_TKT_SRP363933	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.40334
SNU869	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16765
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.53192
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-8035-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
partner	GeneRIF Biological Term Annotations	1.0	null
COLO741_SKIN	CCLE Cell Line Proteomics	1.0	2.24096
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BATF	ENCODE Transcription Factor Targets	1.0	null
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26939
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_hexaplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Tranylcypromine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135427
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.12964
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.279
QB-69-QH67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342524
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.5033
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1798
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2026
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2471
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0368
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K65137277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50413
hnf1a_16297991_hek293_embryonic_gof_mouse_gpl96_gds1499	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.02351
BRD-K82863660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10836
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31134
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14903
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.219398
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of phosphatase activity	GO Biological Process Annotations 2025	1.0	null
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
etoposide_homo sapiens_gpl10558_gse33990	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pleckstrin homology-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
HEY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00462573
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10863
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE66724_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8792_KD_LKB1_SRP045048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.6164
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1195	CCLE Cell Line Gene Expression Profiles	-1.0	-2.60262
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNOT3-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949245
HSF1_KD_GDS1733_752_human_HeLa cells - 2 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SW1417	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58833
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of dephosphorylation	GO Biological Process Annotations 2023	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16972
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60242
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL2_SKIN	CCLE Cell Line Proteomics	1.0	2.50904
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ParietalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.963473
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04519
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HD-01B-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78960724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16641
NCI-H64	GDSC Cell Line Gene Expression Profiles	1.0	2.76918
A549_CUDC-101_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137979
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2788-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897503
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB4	ChEA Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4595-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10191318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13843
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Unnamed_9_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95343362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10037
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144487
NCIH1836	CCLE Cell Line Gene Expression Profiles	1.0	1.79696
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	5.83618
FU97	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4433
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ntera2	HPA Cell Line Gene Expression Profiles	1.0	1.35466
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88212
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5271
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.949201
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.856942
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10066
BRD-K50479239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14657
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2381
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.54552
BAY-11-7085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26595
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary pulmonary hypoplasia_Lung Tissue_GSE1363	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.20803
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18361
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56052
OVCAR-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
K562_Tie2 kinase inhibitor_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163089
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50161
GSE111247_2_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7465
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64719
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
secretion	GeneRIF Biological Term Annotations	1.0	null
mtmr6	GeneRIF Biological Term Annotations	1.0	null
GSE152441,GSE152442_1_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	220.032
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55231
SUP-M2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.28789
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03672
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868257
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Embryo Loss	CTD Gene-Disease Associations	1.0	1.10033
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17537
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K96353852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41003
hsa-miR-449b	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16898
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74103290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11412
hsa-miR-367	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of phosphatidylinositol dephosphorylation	GO Biological Process Annotations 2025	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76328
BCLAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906049
ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.63544
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56093
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46613
GSE128099,GSE128159_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52634604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14855
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3986
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883279
BRD-K29086754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04572
GATA4	ChEA Transcription Factor Targets	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60194
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KANSL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00473692
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97693
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49741
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24799
Sigmoid_Colon	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.32103
Hypertension	HuGE Navigator Gene-Phenotype Associations	1.0	null
MDAPCA2B	CCLE Cell Line Gene Expression Profiles	1.0	1.65862
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.84098
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2296
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K31559225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30671
hsa-miR-485-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844445
BRD-K30632097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14487
Coelomic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
ZZZ3	ENCODE Transcription Factor Targets	1.0	null
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042182
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2002
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A4ZW-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRAK2_knockout_76_GSE24264	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.19498
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.880658
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40452322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25266
BRD-K05128360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01943
icSARA deltaORF6_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.20964
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33557
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0692
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.150176
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.391
BRD-K61791241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14347
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69246
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385