association	dataset	threshold value	standardized value
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5311
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07204
GTEx BloodVessel 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	8.36338
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28194
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59665
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51773
TTPAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04236
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07564
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33894
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26555
GSE199541_2_v_4_mbd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.264
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7276
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.23
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30242
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13136
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.2463
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90357
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22725
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTGES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06959
CRCGN015_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84498
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MPST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42548
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2237
PMC9734180-41398_2022_2274_MOESM8_ESM.xlsx-Supplemental_Table_2-Supplemental_Table_2_Genes_regulated_by_TFEB_expression_are_altered_in_MAPT_p_R406W_brains_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07462
GSE165548_2_v_4_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00047
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM131A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82753
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1394
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01722
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1949
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3175
PMC11003700-pbio.3002240.s011.xlsx-MYCN_2_peptide_counts-Gene_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Toremifene Citrate_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151104
CRCGN013_HEPG2_24H:I16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.00117
GSE229580_0_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32813
chr17_73186510_G_A_b38	GTEx eQTL 2025	1.0	3.09628
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19066
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3649
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZFP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36174
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17097
CRCGN013_HEPG2_24H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22256
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39994
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48852
CCNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67065
GSE137144_2_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CPXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37217
GSE114992,GSE114993_4_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.159
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.4487
PMC10624900-41467_2023_42825_MOESM13_ESM.xlsx-Module_3-ZNF195_ZNF195	Rummagene Transcription Factor Associations 2026	1.0	null
TUBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46643
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.533
LRRFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01988
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
9656_USP39_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.562271
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
11301_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.503354
SHPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85994
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.324
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11257
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05906
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
GSE220520_5_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58056
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41368
CRCGN008_HEPG2_24H:A24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0481
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
ECE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29309
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20548
ECPAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69201
216_AIFM1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.620708
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.449
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71608
GSE229973_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53357
HECA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53839
H4C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70712
CPEB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12863
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203329_2_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.659712
CRCGN008_HEPG2_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0494
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1759
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193402_0_v_4_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78254
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.690566
PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29065
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9112
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
496100553_TCx_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.72272
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30635
GSE254848_4_v_3_ptges_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211128_4_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PCDH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03135
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0798
9684_UTP20_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.579379
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr17_73232798_C_T_b38	GTEx eQTL 2025	1.0	1.14626
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0944
EIF3I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26977
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4342
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2672
UFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4363
GSE154577_6_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.8782
TNKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26637
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
5485_NBR1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.565841
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
SLC19A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09694
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63885
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.6461
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
DAGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44249
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165122_0_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17414
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2861
GSE180951_6_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17353
PMC10592962-media-4.xlsx-OC2_genes-gene_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
SLFN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88875
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0092
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.520853
GSE137144_2_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4609
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
3086_FIP1L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.501285
CRCGN015_MCF10A.TP53.M_24H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08475
PMC7771094-12920_2020_832_MOESM5_ESM.txt--ATF2_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
ZIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15681
CCP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35298
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
4470_KRI1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.526938
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0018
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81636
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3505
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4731
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2321
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01633
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172247,GSE172250_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33751
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.4918
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03336
CRCGN015_MCF10A_48H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01119
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.325
chr17_73191639_T_C_b38	GTEx eQTL 2025	1.0	1.70681
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140322_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29678
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4072
2858_FAM136A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.546748
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1241
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62625
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41528
7454_RPL27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.603261
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02918
5735_NOL6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.819202
GSE207787_1_v_4_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18854
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88422
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
4932_MED12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.510049
GSE93156_1_v_0_idelalisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14509
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8237
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06546
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01741
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41648
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14645
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07491
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68461
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20395
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25215
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216394_2_v_0_pfkp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153189_1_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01694
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21545
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50442
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64103
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.06007
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1677
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33691
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03473
OGFOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53393
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
5903_NUP93_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.79669
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29787
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59575
chr17_73232628_A_C_b38	GTEx eQTL 2025	1.0	1.96457
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220520_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Amp_AA-TCGA-Unnamed_20_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5640240-ppat.1006668.s013.xlsx-BETA4-379_common_elements_in_shEP400-1_BETA_shEP400-3_BETA_shMYCL_BETA_and_shEP400-2_BETA_BHLHE23	Rummagene Transcription Factor Associations 2026	1.0	null
GSE121319_1_v_2_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	1.0	null
NOL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19088
PMC6742760-41467_2019_12079_MOESM10_ESM.xlsx-Data_S8-Supplementary_Data_8_Target_genes_of_FOXA1-bound_enhancers_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29103
2731_ESF1_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.517749
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57818
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54478
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RECQL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56444
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235066_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12504
GTEx BloodVessel 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	27.1481
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXO27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1374
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
OSBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17789
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEx BloodVessel 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	17.131
GSE129389_0_v_1_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_1_BioID_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24492
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43024
SCARB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16242
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60525
HNF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02692
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
5658_NFYC_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.563172
496100556_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13161
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ABCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08123
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6977700-aging-12-102667-s004..xlsx-Stage1-The_identified_3126_dysregulated_LmiRM-CTs_in_stage_1_of_MI_1_day_of_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211128_9_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
6611_PPAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.530159
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
chr17_73235465_A_C_b38	GTEx eQTL 2025	1.0	2.62677
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129858,GSE129859_1_v_3_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_10_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Linifanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157849
HIBADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00662
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0266
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7803
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5629
4108_IMP4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.564984
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2436
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87623
High light scatter reticulocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
569_ASB8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.610921
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242199_2_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0094
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_unique_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
6748_PRIM2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.505572
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51042
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.791
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193541_1_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.359
TUBA1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01457
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4521181-oncsis201520x8.pdf-50-CSRNP1_CSRNP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZDHHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03386
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34076
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155800_1_v_0_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7447
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26897
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
chr17_73240015_T_C_b38	GTEx eQTL 2025	1.0	1.14369
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22608
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39856
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7115
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3506
PMC9376070-41419_2022_5157_MOESM15_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_of_CYTOR-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.49478
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.0595
CRCGN014_HEPG2_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04611
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51696
GSE246053_1_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73631
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14169
PMC10830421-41589_2023_1452_MOESM5_ESM.xlsx-HEK293T_MAX-Tg_tissues-Unnamed_0_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
MMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49787
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
7141_RBBP5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.592862
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.510418
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83363
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.9924
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25951
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1861
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2125
TPRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.182
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4306
CRCGN008_HEPG2_24H:I03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04115
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7468443-Data_Sheet_5.xlsx-LPS_2h_over_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.1047
PMC10290283-biol-2022-0622-sm3.pdf-331-PGR_PGR	Rummagene Transcription Factor Associations 2026	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6808
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5275
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61928
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05975
PMC6977700-aging-12-102667-s006..xlsx-Sheet1-The_identified_941_dysregulated_LmiRM-CTs_in_MI_using_traditional_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32176
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE244072_2_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72075
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:J06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22634
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13179
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
4043_IFITM3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.515727
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STXBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03643
JRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12599
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23465
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE236003_0_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.81495
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22282
2833_FAM111A_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.563735
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2506
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05038
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
4953_MED30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.505102
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_unique_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0981
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8192
CRCGN014_HEPG2_3H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43483
GSE229580_2_v_1_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54316
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146070_1_v_0_edem3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13269
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.889
GSE161846,GSE161849_1_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235066_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5009
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_7_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8190596-mmc2.xlsx-ETV6_mut-ETV6_mut_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1735
chr17_73231814_A_G_b38	GTEx eQTL 2025	1.0	3.63423
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3503
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211128_9_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_0_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40146
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53173
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.1167
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211128_3_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEx BloodVessel 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	15.0775
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6777
GFUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00128
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10967149-12903_2024_4167_MOESM3_ESM.xlsx-LPS_VS_LPS_PDLSC-CM_776-Gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75066
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10741
PMC9068765-41467_2022_29960_MOESM14_ESM.xlsx-TP53-Unnamed_2_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158975_0_v_1_spp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36522
496100524_PCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07053
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21659
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00538
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01336
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46995
GSE132369,GSE132371_4_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6977700-aging-12-102667-s004..xlsx-Stage3-The_identified_641_dysregulated_LmiRM-CTs_in_stage_3_of_MI_1_month_after_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19178
FXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68721
4593_LIN52_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.735859
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05885
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.9329
9210_TPP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.589647
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr17_73233212_C_T_b38	GTEx eQTL 2025	1.0	1.68736
7251_RFFL_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.625534
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
7491_RPP30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.684101
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.84371
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8562
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8822
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr17_73192144_C_T_b38	GTEx eQTL 2025	1.0	1.12831
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.4025
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44406
GSE153064,GSE153065_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0505
4844_MARCH3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.507213
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6977700-aging-12-102667-s004..xlsx-Stage2-The_identified_459_dysregulated_LmiRM-CTs_in_stage_2_of_MI_4-6_days_after_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30309
GSE101546_2_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7933708-mmc2.xlsx-DNMT-target_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53012
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18627
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20006
2553_EIF3I_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.504425
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_8-ILL1_T_Cells_FOXP3_FOXP3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DDX53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01669
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
2789_EXOSC2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.525967
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.505413
SNRPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75442
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19588
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49617
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.006
GSE180951_6_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07444
CRCGN016_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31801
CRCGN008_HEPG2_24H:A04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4035
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7054
GSE254848_4_v_13_ptges_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.33
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12039
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95785
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11003700-pbio.3002240.s011.xlsx-MYCN-IMR32_RawData-Unnamed_2_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
7455_RPL27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.504367
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTP4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26814
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_3H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17971
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.864135
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47899
GSE198165,GSE198166_7_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE108614,GSE108615_0_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90614
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.596
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10194
PMC6080909-JEM_20171312_TableS1.xlsx-Each_THP1_Pulldown_Expt_Targets-Unnamed_1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07262
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3582
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37754
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9068765-41467_2022_29960_MOESM14_ESM.xlsx-TP53-Annotation_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64597
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_5_TbID_-biotin_ERM_proteo-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25925
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.782459
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.79797
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.819
496100427_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09265
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61618
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KNSTRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50663
GSE183113_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.773
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_3_TurboID_1hr_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39714
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7951
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
2622_EMG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.619465
CRCGN016_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09788
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.77701
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215132_1_v_0_ptpn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13906
GSE148066,GSE157787_2_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22758
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16868
2793_EXOSC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.509552
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
STK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07013
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
9587_UMPS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.554533
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02396
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.108
PMC6977700-aging-12-102667-s004..xlsx-Stage4-The_identified_749_dysregulated_LmiRM-CTs_in_stage_4_of_MI_6_months_after_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134316_1_v_0_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANAPC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22333
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
537_ARPC3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.52723
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C17orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8925
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_2_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195786_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14196
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9951
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137144_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.044
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31608
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Veliparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144806
LIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29009
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.7764
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.35862
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9998