association	dataset	threshold value	standardized value
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4448
FAM162A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32983
Leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Uterine cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91158
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32364
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Allergic rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
HTR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57928
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40453
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67922
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18678
SORD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
ZNF599	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81054
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158438_4_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35389
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30406
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16985
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2354
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12397
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11927
SERPINH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70129
TTPAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70096
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29707
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
ZNF436	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14298
RPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97466
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33262
CBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45109
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5617
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3518
TEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34775
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45158
ARL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81051
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54361
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84337
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10409
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48688
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15578
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7631
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81441
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65455
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59217
TRIM35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32561
UBXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17196
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29233
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67245
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
Shell gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
ANP32B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35794
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89872
ZDHHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42194
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
PVR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6928
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Calu-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
IDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55992
CCNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80764
DCP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22866
YES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1592
GSE163862_1_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.26129
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12654
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28948
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
PML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28931
TRIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92384
DNAJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32619
MFSD6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05867
S100A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74397
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79169
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44295
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
PSMD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59942
OSBPL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00918
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.103
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7047
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37292
GSE130475_1_v_2_thpo_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61759
CLIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59221
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46736
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SEPHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54732
Social phobia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
RAD51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93168
MYEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10861
METTL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44323
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14675
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
TMEM201	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67941
STAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16331
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73792
GDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65377
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98161
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.06067
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40446
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.67261
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RASSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75948
Rosacea symptom severity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
GPR63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92711
CTCFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7947
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.93979
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24474
IQCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87015
WDR82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56877
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42911
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06672
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30643
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83059
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
POLR2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14048
BAZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7048
Viral infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.672
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24099
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85458
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8155
Autoimmune disease of endocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.549
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0055
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55643
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72879
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08907
HOXB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60697
INSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21522
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29925
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24784
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
GPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84227
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GRAMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66803
LLPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64776
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11409
TMEM223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58894
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
RAB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65012
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13369
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64181
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5895
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9878
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47758
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mucin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87832
DDIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94115
GSE189756_1_v_2_rbpj_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77792
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38839
Graves' disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.549
PMC11443809-12967_2024_5663_MOESM3_ESM.pdf-43-CRX_CRX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64013
GSE188869,GSE188871_2_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PGRMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44549
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
POMC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34934
UTP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25922
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
MIGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43891
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1364
PMC11551338-pnas.2411189121.sd01.xlsx-AHR-Unnamed_0_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
INPP5J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52184
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91915
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29002
NDUFA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03598
SLFN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41334
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10798
GLI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42927
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83647
TFB2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82784
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24981
ZNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89956
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52159
GSE204784,GSE204787_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08074
BEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06951
FANCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58305
GSE176008_8_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07444
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2674
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80589
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3607
ZNF358	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30203
SRSF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06456
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10087
CRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94589
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08429
VPS26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44943
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8585
Gastrointestinal system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
ELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76532
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
INPP5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03484
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54774
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00016
DPH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44535
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31147
Adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
PMC11949941-DataSheet1.pdf-52-ELK4_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
MCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01003
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
JTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84568
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9804
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
IGFBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39662
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16893
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3349
EPHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17454
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55012
ERBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5018
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97056
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21869
METTL21EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6985
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	7.10451
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.801
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69006
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RETSAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97062
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75208
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98237
GSE158834_7_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Respiratory allergy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
ZNF821	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92802
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8166
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56988
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55219
MAPKAPK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6722
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0636
PLXNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
GCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49307
NCCRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95105
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
Bronchiolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
RNPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97338
TRUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44171
DLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7622
RBM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28695
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63219
P2RX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
Uterine disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
Hemoglobin levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.35229
IGSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37193
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44513
DAAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79982
GNG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35889
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6991
SUPV3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24693
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09307
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88994
FAM78A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6839
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93358
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93274
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34085
White sponge nevus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
SLC9A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05319
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24084
ZNF474	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23856
CD55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33618
ETV5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05633
BTN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49691
ORMDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99664
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9214
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63774
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4704
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75718
RCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06661
PGM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33675
ABCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02961
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59208
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76571
Harderian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
SFXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81513
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53795
BLACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71428
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231511_0_v_1_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29394
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33137
Intestinal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
ZNF816	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22715
Bell's palsy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZMPSTE24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0245
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
FXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1275
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39263
MMAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23527
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
UFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4363
ATP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57919
BRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37721
ATMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79261
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33434
ABHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17397
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54041
PTRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43592
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
FOXD4L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60237
Cutaneous lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1548
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60337
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
CGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2514
ACOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07038
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5471
PANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36006
Gestational age at birth (maternal effect)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
HUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28316
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49538
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DENND4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57904
ZNF747	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0199
SLC20A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15825
MOSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18238
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96359
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03545
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1911
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10759
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84584
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5872
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01454
Membranous glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
NEDD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42472
ADGRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98945
Side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.086
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
ARHGEF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86647
GTF3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40858
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71068
NUMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53373
TAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08256
GSE167474_1_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57526
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
ITGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62082
GSE207301,GSE207303_0_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0835
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
Gastric fundus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.837
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.6196
SLC44A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27022
CROCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85634
PCDH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01604
BRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79091
SLC4A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05895
E2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31638
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8964
Cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.176
MUTYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57891
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07313
FANCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67412
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97691
Hyphal tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3907
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57535
CYCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50858
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6438
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7998
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06714
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C12orf29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86576
UIMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25041
Disease by infectious agent	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.672
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0002
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51008
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25042
Esophageal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAMHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9993
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6841
Fundic mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.232
LAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88305
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4653
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9985
ZFHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91433
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17613
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8547
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39053
Female reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85465
DCANP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13289
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
COTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49699
BLOC1S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74497
Pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37063
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
TTYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64705
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BABAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23655
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82205
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4681
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85218
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5743
SPTSSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54371
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAP7D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00905
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.46564
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44261
Submucosal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06491
MUS81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13617
FAM32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06535
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5956
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.054
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3446
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46554
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.12873
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44321
TOP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35777
Stevens-Johnson syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.09
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.547
SAMD4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23147
QTRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52567
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6547
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98893
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46821
GSE186440,GSE186443_1_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05018
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZGLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09025
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00088
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26536
ELK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81101
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62373
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00829
Pituitary gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49923
Hip circumference adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84591
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02117
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49934
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49963
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.38247
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48995
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18793
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01197
MTMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79309
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1892
Swine influenza	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.672
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91399
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
SLFN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98406
NAP1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13119
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75714
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36547
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36129
ATP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56851
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92592
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66591
PSENEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
GSE129241_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114992,GSE114993_1_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2778
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
ENSG00000170846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69918
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21423
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93669
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36292
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10398
TOR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82032
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
NPTXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2339
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
TULP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86952
OV2008/C13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.004
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32228
CUL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4263
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4804
ADCY9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51073
RPS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16154
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54653
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24042
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55384
C1orf159	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58835
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nose disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2558
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56137
TTC38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41001
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
NDUFA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66123
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60592
APOBEC3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37142
WDR74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51042
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE110676_0_v_4_mef2b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29255
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207301,GSE207303_1_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30584
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7808
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37686
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88339
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_4_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64333
CLASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58445
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61597
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99468
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39419
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29065
Cervical cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
SEPTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51326
Endocrine organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83765
KIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58461
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
CEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09549
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMRTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27689
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38456
TGFBRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75663
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Nasal cavity disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
TLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65833
FADS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72995
FZD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53015
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CKAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45398
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3476
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6332
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.054
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43
ZNF226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35431
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
ZNF722	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77897
KCTD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87357
CLASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81809
GZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92496
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79738
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.975
TRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51952
NUP188	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68355
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12656
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30184
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3521
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50465
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
ZNF684	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20179
MAMLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15221
CFAP126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90657
Pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.467
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57829
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
Allergic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
chr6_30953113_G_A_b38	GTEx eQTL 2025	1.0	1.21834
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.874
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17429
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1122
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21281
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
SFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26052
E4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16967
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HIV-1 control	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
DQX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04053
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1771
ANXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21243
SENP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5584
NPAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48831
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lonafarnib_Panc 03.27	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00904657
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48161
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3835
AGFG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42617
CTDSPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03414
PGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57155
USP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02449
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0734
RNF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57431
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9222
SMARCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66486
GSE139325_2_v_3_cd36_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF546	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65867
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85513
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47289
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63321
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
KPNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94249
SLC25A32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72709
KLK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83768
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7268
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28233
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AP3M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4818
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
TAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84805
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31743
Inhibin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
FANCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59459
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MB21D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65918
RHOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7616
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04603
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
16-HBE14o cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
USP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78711
EIF4G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13021
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04559
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PHLDA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21569
Stomach	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224157_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3866
496100587_FWM_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11199
GLUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77879
PGLYRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24902
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.672
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20928
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55038
KMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96041
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0972
STXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6095
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77083
CXCL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90531
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33348
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75133
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98768
PTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67933
ZSCAN29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55456
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50551
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60719
SYCE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16282
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
MED30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46039
TMEM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60408
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9958
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3615
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41596
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63883
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16951
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39474
KNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67776
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21604
PPARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35374
SLC39A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3191
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8075
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
nBAF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
Type IV secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
IFI6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23465
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45203
Oxyntic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.048
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49196
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76782
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95078
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4849
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GLUL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22583
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21441
PMC11148097-41698_2024_569_MOESM2_ESM.pdf-213-ZNF277_ZNF277	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99297
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52449
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84243
PPFIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72408
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51278
HOXC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43858
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40427
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63757
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
MRPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
Pulmonary function (smoking interaction)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
FRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12802
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40012
GNPNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14977
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3394
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09039
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20379
Nephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.281
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15308
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36586
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67399
PMC11551338-pnas.2411189121.sd01.xlsx-FXR-Unnamed_0_NR1H4	Rummagene Transcription Factor Associations 2026	1.0	null
MARCKSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07646
NSMAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51989
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87484
DECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39099
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39878
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.549
UNC45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62199
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28111
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7284
TM9SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69191
HOXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74393
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02611
Rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38062
B4GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0926
MSMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36099
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04397
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74921
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90527
UBR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78125
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12479
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89022
RCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20589
GSE131649_4_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45068
IGF2BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94152
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.162
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34326
ZBTB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26647
ZZEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0377
PRNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37635
CLCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72177
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCP10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30552
XPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39745
MLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53728
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28338
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9863
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HYAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23083
PMC11551338-pnas.2411189121.sd01.xlsx-PXR-Unnamed_0_NR1I2	Rummagene Transcription Factor Associations 2026	1.0	null
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75984
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28035
ITGB1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52854
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49885
AURKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49954
NUDT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68156
MAGED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29309
SKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44428
Pancreatic juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
RPP25L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5441
ZNF530	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55311
LHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0289
Autosomal recessive spinocerebellar ataxia 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
PMC10725467-41467_2023_44159_MOESM4_ESM.xlsx-Supplementary_Data_10-Supplementary_Data_10_Nonsynonymous_mutations_in_TFE3-RCC_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75684
Cervix disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65296
RUNX1T1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82772
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17477
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
ELK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48941
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1215
SLC25A30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89666
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51903
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58542
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25546
GSE186440,GSE186443_3_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45239
TNRC6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42013
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50904
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63828
UCHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08529
Progeria associated lipodystrophy	WikiPathways Pathways 2024	1.0	null
GSE186460_0_v_2_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55568
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61584
CORO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32936
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
ZCCHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21933
TGIF2LX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0459
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5405
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48373
MYO1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85119
Serous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56132
Bronchiolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
NUDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68763
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51023
GJA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01297
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43495
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93697
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PFDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.33386
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.363
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27261
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9238
GEMCITABINE	DGIdb Drug Targets 2026	1.0	0.653481
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99969
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.923
Gastric pit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
MRPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32265
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.538
DISP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28511
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20911
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21504
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74017
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19863
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52696
GSE222103_0_v_1_ybx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1023
Nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
Oropharynx cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2239
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11286
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99612
ZNF319	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17244
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.83834
TGIF2LY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75684
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.5602
YIPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2497
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75488
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
Cytoplasmic side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.171
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63158
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Functioning pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
Heterotrimeric G-protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.182
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.207
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0546
POLR1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3381
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92216
SIGIRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71598
Budesonide_Panc 03.27	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.027357
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7443
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47092
MGAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5328
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52684
ELOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63039
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8713
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4586
SMARCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29241
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTRF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47325
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19874
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2561
STK38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97623
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.0864
PTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61844
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4375
ZNF652	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61918
Specific phobia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03569
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91819
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4305
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0243
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61313
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24293
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85879
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41423
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26742
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06245
RBMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09434
RBMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59716
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7668
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.33979
NDUFAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52454
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
LRRC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32714
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pituitary gland benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29185
SKOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93502
H2AC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99894
CITED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64327
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
TAS2R5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50841
INSIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9587
GSE193993_1_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PRXL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5807
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5311
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67512
SNCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40024
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76759
GMPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46566
IRF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31248
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.316
KLHL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42296
POLR2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28638
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21932
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70678
Pharynx cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
APOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81109
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6718
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52695
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56578
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98484
SUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43833
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85116
MRPS18C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4664
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13616
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1438
RAB33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11228
GRHPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64351
ORAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58996
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40802
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3968
Glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00877
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39232
GSE186287_2_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PCNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KCNK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5931
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07591
MID1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69673
GSE200839,GSE233826_3_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4122406-pone.0104158.s010.pdf-22-DLX5_DLX5	Rummagene Transcription Factor Associations 2026	1.0	null
PRELID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08686
FBXO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30108
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25545
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1919
MRPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30043
BHMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9015
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91282
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98238
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16406
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64262
FAM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63719
ZNF876P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36121
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04613
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64784
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
ZNF500	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88737
Baraitser-Winter syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
THEMIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36806
Corneal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31411
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22194
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04076
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
AUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96111
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36719
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
ZNF891	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00057
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8125
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KCNJ14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37215
TMEM216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66677
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99797
Idiopathic membranous nephropathy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.95229
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3148
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66306
NCOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46834
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
Respiratory bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.253
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01212
MMP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76019
EPHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65462
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76001
CARBOPLATIN	DGIdb Drug Targets 2026	1.0	0.6015
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37241
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC35B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02703
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75372
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49676
MBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1744
GSE158975_0_v_1_spp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PARP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17428
DMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07076
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.106
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50248
ZBTB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31552
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.125
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08959
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9714
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2389
RHEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06381
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.33517
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.34697
Psoriasis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
RIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48191
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SETD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.58792
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	141.114
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73105
Extrinsic component of cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.181
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2212
ZNF772	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67023
PPM1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72963
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.795
PMC11252802-pnas.2322203121.sd15.xlsx-Sheet1-TRP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10606
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.5459
GSE186440,GSE186443_6_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHRAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3421
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39368
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2489
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.2247
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
PJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24272
ARPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96534
Indeterminate leprosy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
GSE216043_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Upper respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.627
KIF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27838
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1916
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67286
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.338
PRXL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79012
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76864
Hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MITF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05606
FKBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01459
LRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55914
FASTKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76406
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24297
Influenza	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.672
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41812
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39278
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5603
AGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80399
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77042
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64414
Bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.349
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88645
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
NME6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90787
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99814
RFX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77621
NRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06073
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05753
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80843
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44159
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06378
NAA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14553
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
Lamina epithelialis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
ZNF420	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4021
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
TRAPPC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93313
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3715
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77284
SLC19A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37177
SAC3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55826
TMEM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36752
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0111
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
FAM111A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94951
HIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32764
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4805
PCDHB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50949
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35177
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35749
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-PITX1-HIT_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
OSBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68622
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99017
MGAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21506
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
GLO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89491
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82919
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76489
STX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44238