association	dataset	threshold value	standardized value
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44013
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
BRD-K03654379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11163
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.542566
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30038
BRD-K22380647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59407
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GaMG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	2.42945
AB-84-PK04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307448
4695_LSM5_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.543101
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PC3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04777
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825485
BRD-K92825272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22007
BRD-K64722080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22215
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08972
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08595
h4 histone acetyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56531
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00721
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50952
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94062
BRD-K37151525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11393
GSE196540,GSE196542_2_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312815
BRD-K14394756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06744
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ozagrel-2942	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K35587518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00842
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25818
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
chr16_3488565_T_TCTCA_b38	GTEx eQTL 2025	1.0	1.93505
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.12495
BRD-A88461048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54318
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07535
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27096
Eosinophil Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.917729
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K54507743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09913
BRD-K53774433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0971
H3K36me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42225
HD-89-HC56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.348923
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01003
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K33697018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09268
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10349
USF2	ENCODE Transcription Factor Targets	1.0	null
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08381
genome	GeneRIF Biological Term Annotations	1.0	null
BRD-K89328601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04486
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56591923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09963
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09388
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.916675
hsa-miR-5047	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
Plastid thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12978397-wjon-17-02-247-s002.xlsx-S2-Suppl_2_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.08187
hsa-miR-486-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE186483_1_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51151
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
1212_CAST_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.643048
BRD-K44576681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42068
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.876658
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39751
BRD-K85392247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17287
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06068
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.80332
BRD-K95937143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57102
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.296
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52143
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
golgi membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
organisms	GeneRIF Biological Term Annotations	1.0	null
protein complex subunit organization	GO Biological Process Annotations 2015	1.0	null
CAL-62 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
YH13	DepMap CRISPR Gene Dependency	1.0	2.34219
hsa-miR-4675	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
ED-81-ZH14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206173
artery disease	GWASdb SNP-Disease Associations	1.0	0.128432
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3269
COLO680N	DepMap CRISPR Gene Dependency	1.0	3.28997
BRD-K52833964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47126
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3268
chromatin organization	GO Biological Process Annotations 2025	1.0	null
GFI1B	ChEA Transcription Factor Targets	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37892442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19304
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13641
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH510	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54963
VCAP	DepMap CRISPR Gene Dependency	1.0	8.79746
CCT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91454
SP1	ENCODE Transcription Factor Targets	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02091
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15326
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00592
BRD-K83115645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15864
histone h4 acetylation	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61492
Hypertension	CTD Gene-Disease Associations	1.0	1.09436
BRD-K04980212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06085
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOXP1	ChEA Transcription Factor Targets	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75909618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04575
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.22488
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32132
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.02366
BRD-K88590066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20862
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50518
silver-russell syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.23126
spleen	GTEx Tissue Gene Expression Profiles	1.0	0.933139
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-29c	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33039
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926678
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.86248
MTA3	ENCODE Transcription Factor Targets	1.0	null
GSE143643,GSE143644_1_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88821
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12292
BRD-K98276754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11443
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K03599607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27274
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.923
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.945175
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40298
placenta	HPA Tissue Protein Expression Profiles	-1.0	-1.41197
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SP2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-680N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
BRD-K20069402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32716
GSE120595_0_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
golgi apparatus part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.949365
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21001
RF-58-GQ76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220386
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12447
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45197
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UBLC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54124
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33085
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.93576
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Perturb_8689_KD_FAT1_SRP358313	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.14589
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hypertension	GWASdb SNP-Disease Associations	1.0	0.909246
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6237
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.62568
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8497-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39032
2236_DLAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.537719
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12853
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10008
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8214
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70443
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.36233
Monocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9857
BRD-K87580376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49928
AA-46-GL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.387839
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.559333
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.658164
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40216
BRD-K94685203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04128
N-terminal protein amino acid acetylation	GO Biological Process Annotations 2025	1.0	null
peptide N-acetyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96047
BRD-K58112932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44005
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-29b	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
BRD-K74329400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19583
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17791
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846728
pituitary	GTEx Tissue Gene Expression Profiles	1.0	0.881559
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33303
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00322
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989118
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16591
Brain Lower Grade Glioma_LGG_TCGA-DH-A66B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47592
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89000000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38171
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.439993
ALVA31	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.1898
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47409867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11198
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260346
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.929443
Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
SP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNFSF12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00449092
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QC-A7B5-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0482
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4772-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303424
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7124
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.62207
Plastid thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
NFYB	ENCODE Transcription Factor Targets	1.0	null
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218418
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952012
GSE128333_2_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923553
NIPSNAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08908
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00865
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34590335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61948
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54535
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841933
kidney disease	GWASdb SNP-Disease Associations	1.0	1.02027
Lung squamous cell carcinoma_LUSC_TCGA-77-8150-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18081
GSE93309_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.52164
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22038
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.8205
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06388
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56798
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31622
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TTC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43999
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62259
GSE160373_6_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864316
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15967
CEBPZ	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40823
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K17765399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09993
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.999
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21388
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-29-MM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202661
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.896372
sknf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26226
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4833-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.857068
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9804
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323012
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1837
BRD-K50596260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77877
vascular disease	GWASdb SNP-Disease Associations	1.0	0.092465
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MC-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66985689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45091
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07218
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2111
hsa-miR-4734	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Chloroplast stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
H4K20me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8758
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06501
covalent chromatin modification	GO Biological Process Annotations 2015	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879764
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14117311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22641
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95547
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58767
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902075
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00395
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.968295
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6175
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14316
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50543
BRD-K76450502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10838
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5475
BRD-K14375485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02306
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0245
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81713
GSE182680,GSE182683_5_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15259298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03148
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.984093
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51758
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
DF-95-CY55_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231291
histone modification	GO Biological Process Annotations 2015	1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827744
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.3861
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37798
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998279
BRD-K15675930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14041
hsa-miR-29a	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326406
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97929312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00814
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67014046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1215
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1375
hsa-miR-4487	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40778
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49132
TD-69-UA90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312259
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.108
GTEX-U3ZN-2526-SM-3DB7V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830261
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.095003
nfe2l2_20133372_lung_lof_mouse_gpl1261_gds3622	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.2849
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69903
BRD-K87669186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06015
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07985
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4128
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04092
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83368
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Isw1b complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.872848
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11019
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29795
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K06308228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53895
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46655
BRD-A27056524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31572
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.65282
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129725_4_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18588
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02669
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-ARGFX_UP-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_up_to_an_FPKM_of_at_least_2_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB33_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53343197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13972
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAX	ENCODE Transcription Factor Targets	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317871
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14877
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68736
BRD-K15400067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27198
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40401
RELA	ENCODE Transcription Factor Targets	1.0	null
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51392
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917502
intermediate stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07786
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.15181
BRD-K97624853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38002
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-52-MX24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215415
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.711925
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223579
BRD-K47821225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53268
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7391
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K33953218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08592
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87857
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.062
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trypomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040998
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4847
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76497
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DD-74-PJ26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203113
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Huntington's Disease_Blood_GSE1751	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.73617
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08358
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82248
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839984
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K61182411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01074
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K88812218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59588
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A8BK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475649
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.2552
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.882305
metstarting	GeneRIF Biological Term Annotations	1.0	null
GSE223334_3_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85047
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51726
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06471
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12263
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71448
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
Renal corpuscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234995
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71A-01A-22R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K24167233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0438
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K33197627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9466
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823938
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883978
GSE134191_3_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844305
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25171
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07887
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.53717
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246818
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.12193
MLL3/4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.702
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.880447
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78673
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22314
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.20223
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2819
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8691
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95897
SNU719	CCLE Cell Line Gene Expression Profiles	1.0	1.54553
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.463
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.867
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Actin cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC0327	DepMap CRISPR Gene Dependency	1.0	3.89277
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.407402
GSE223908,GSE223909_1_v_6_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217694_3_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28574
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35799
GABP	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.1126
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08194
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1455
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25957
Isw1a complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
MB-72-YK93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265451
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90527
BRD-K56309946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30363
nucleosome organization	GO Biological Process Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2793-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12952
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0085
BRD-K14863829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10852
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A50837272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53121
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7654-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98522669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18442
BRD-K98145661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0225
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61409
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18378
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253948
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.827646
BRD-K33179234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21981
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LEDGF_KD_GDS1580_249_human_293T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17119
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SF-67-CJ22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261774
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382423
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS27	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09062
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85034
transferase activity, transferring acyl groups other than amino-acyl groups	GO Molecular Function Annotations 2015	1.0	null
GTEX-R55F-1426-SM-2TF53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05243
BRD-K51385533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62233
CEBPZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.35275
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64329997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40305
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69219
BRD-K27849471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54586
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72426
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13593
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7069-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995745
BRD-K57821544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04914
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MOTN1	CCLE Cell Line Gene Expression Profiles	1.0	1.59078
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.16933
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53455
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1131
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961126
hsa-miR-3194-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K34297711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03732
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.30155
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833807
Lung adenocarcinoma_LUAD_TCGA-97-A4M7-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCA4-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7859
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.850596
Perturb_12493_KD_ELK3_SRP361792	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.67191
MAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59215
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.952629
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09013
BRD-K48691065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56899
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12947
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80779
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22862
BRD-K34808207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04925
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE-89-TF43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200917
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE474	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.97846
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33768
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE229698_1_v_2_traf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fibromyalgia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95771
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1	ChEA Transcription Factor Targets	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31167
BRD-K07281036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74202
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3772
PCM6	CCLE Cell Line Gene Expression Profiles	1.0	1.35357
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3728
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4117
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971955
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.10025
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28758
POU2F2	ENCODE Transcription Factor Targets	1.0	null
15474998-tableS1c	GeneSigDB Published Gene Signatures	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25171
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75583553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01846
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.59204
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-1726-SM-4JBHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59465
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33547
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1187
hsa-miR-4498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2749
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28965
BRD-K81916372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00664
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914548
HDMYZ	CCLE Cell Line Gene Expression Profiles	-1.0	-3.01323
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K32617235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23082
CRCGN008_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0989
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q8-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973989
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0247
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32794
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14128
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886751
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38378
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28312
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0783
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22873
YY1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29632
Lung squamous cell carcinoma_LUSC_TCGA-43-2576-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein maturation	GO Biological Process Annotations 2025	1.0	null
Perturb_15069_KD_Twist1_SRP150075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23L-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05415
Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59881
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878204
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-675	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K29707171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53434
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980135
internal peptidyl-lysine acetylation	GO Biological Process Annotations 2015	1.0	null
GSE202434,GSE202438_2_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50364
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39869
PMC5817105-thnov08p0972s2.xls-SIX3_MTA3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.672584
protein-dna complex subunit organization	GO Biological Process Annotations 2015	1.0	null
BBC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16451
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K35727000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25615
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13589
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE247862,GSE247863_0_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NELFB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506123
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07183
BRD-K29673910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39875
EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967701
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB415	CCLE Cell Line Gene Expression Profiles	1.0	2.26679
19843711-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AT-A5NU-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21378
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06331
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
D-502MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K28619632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76824
BRD-K86104966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29465
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20354
BRD-K72651085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65319
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47349869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11753
GSE201668_0_v_1_ncor2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12260399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32418
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDAMB361	CCLE Cell Line Gene Expression Profiles	1.0	1.81363
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.987363
6071_PARK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.64738
u87	HPA Cell Line Gene Expression Profiles	-1.0	-1.54198
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846529
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07839394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19876
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053229
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26692
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55727377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57645
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12672
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K52319351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08656
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9555
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36011
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.27545
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50247051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01229
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NMB	DepMap CRISPR Gene Dependency	1.0	3.57684
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70525
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UC-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K52047843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0893
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222668
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10625
8433_SRSF3_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.08108
CRCGN015_MCF10A.TP53.M_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47862
SIRT1_KO_GDS3666_295_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6167
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00856
thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.509813
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13732
BRD-K57786028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42758
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K43387144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74187
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20607
hsa-miR-4722-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
inner CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861136
SKMEL19	DepMap CRISPR Gene Dependency	1.0	3.18522
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0614
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
dihydroergotamine-2081	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31184
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.159
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97233
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826756
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.541637
Metacyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.423
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01026
Lung squamous cell carcinoma_LUSC_TCGA-77-8128-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29166
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97006
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5692-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11185845-NIHMS1996282-supplement-Table_S1.xls-TableS1_txt-CB_TBL1XR1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
kidney_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.846923
peptidyl-amino acid modification	GO Biological Process Annotations 2015	1.0	null
SUIT2	DepMap CRISPR Gene Dependency	1.0	4.65607
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:D02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.90215
histone H3 acetylation	GO Biological Process Annotations 2023	1.0	null
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05945
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22829
ventrolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06422
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340388
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55848
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.2731
Heterochromatin island	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34199
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5571
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GJ-01A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NLGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50335
EBF1	ENCODE Transcription Factor Targets	1.0	null
AF-80-GK24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225968
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13818
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
knockdown	GeneRIF Biological Term Annotations	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-35650195-DSRCT-HUMAN-MESENCHYMAL-SARCOMA	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3417-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
C1orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1228
hsa-miR-1207-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K17410712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50965
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Golgi membrane	GO Cellular Component Annotations 2025	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160373_5_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K87092114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46735
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2767
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64696
N-terminal protein amino acid modification	GO Biological Process Annotations 2023	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988585
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87857
BRD-K79732056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00064
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.940559
BRD-K31197843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19527
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14025
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1042
eukaryotic	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881658
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.519431
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CerebellumPeduncles	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.905637
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.83499
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21921
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07934
MAFK	ENCODE Transcription Factor Targets	1.0	null
BRD-K79807180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06471
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19866
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89331
GTEX-O5YW-1526-SM-3MJGL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04681
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_pos_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
histone acetylation	GO Biological Process Annotations 2015	1.0	null
PPP6R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50781
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.85709
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840032
BRD-K23701005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04115
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18302
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.947306
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3158
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887287
EGR1	ENCODE Transcription Factor Targets	1.0	null
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50305
MYCN	ChEA Transcription Factor Targets	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53438
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17085
GSE164463_4_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83439
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48537
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910958
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22392
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15607890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43775
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060534
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
histone acetyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A735-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MELHO	CCLE Cell Line Gene CNV Profiles	1.0	1.44297
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06743
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07767
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30415
UMUC1	DepMap CRISPR Gene Dependency	1.0	2.37024
POLR2A	ENCODE Transcription Factor Targets	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K48012250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27519
BRD-K06320746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14822
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6373-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kinetoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.819
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K82194980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55858
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.34915
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00213
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374161
BRD-K11700411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44157
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.06676
BRD-K48681121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34726
BRD-K60862683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57593
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26267
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845273
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K76618080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42063
MB-46-BT89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.929582
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2087	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54912
Lung squamous cell carcinoma_LUSC_TCGA-85-8580-01A-31R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931054
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.15055
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Origin recognition complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79555018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16591
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.050664
RA-49-ZB08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201303
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88077
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4633
PD-74-GP60_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440496
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41323
peptidyl-methionine modification	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4757-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
RFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49948
POLR2A_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08109
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP1N	DepMap CRISPR Gene Dependency	1.0	3.14987
p107_Deficiency_GDS3176_606_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HS695T	DepMap CRISPR Gene Dependency	1.0	6.47701
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11117
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934852
COLO 849	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.88959
BRD-K74834319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01484
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50062
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06284
hsa-miR-4763-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ELK4_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11658
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07838
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07867
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053258
BRD-K64356525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06907
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166317_2_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20768
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-OXRK-1626-SM-3NB17	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42853
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22028
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.034357
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20352
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83138
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.41197
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8359-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0872
NUPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10905
BRD-K95485901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17873
hsa-miR-762	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44311
UBB_KO_GDS3906_494_mouse_Testis -  21 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.237
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837663
deltaEF1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.94835
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26737
CRCGN016_MCF10A.TP53.M_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02362
SP2	ENCODE Transcription Factor Targets	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.894958
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26200435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43632
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10549
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21955645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25251
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-04-NG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236828
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09474
protein N-acetyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
RA-89-RR01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.302234
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00995
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38345
N-terminal protein amino acid modification	GO Biological Process Annotations 2025	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59502
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14533
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15083
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.48577
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3269
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OCUB-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
histone H4 acetyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71679
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-12.4441
CHD2	ENCODE Transcription Factor Targets	1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.299242
primary motor cortex (area M1, area 4)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37678
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_18606_KD_Lsm1_SRP327180	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.37621
bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.002908
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8518
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01904
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.531187
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mp10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
BRD-K37131263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25079
CREM	ChEA Transcription Factor Targets	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23792
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17335
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82517
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52385
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23875
MYOG	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Euchromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.202
HCC1187	DepMap CRISPR Gene Dependency	1.0	2.00244
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56145
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11481
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01866
urinary bladder	HPA Tissue Gene Expression Profiles	-1.0	-0.83137
BRD-K75981085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08206
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28056
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31034311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07214
BRD-K89459607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06474
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.16269
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02334683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13835
BRD-K84932026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22052
BRD-K51791049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19277
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907526
Brain Lower Grade Glioma_LGG_TCGA-FG-7636-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endoplasmic reticulum cisternal network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.385
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.89772
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.960232
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36314834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36061
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	1.70448
NCIH1876	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35136
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914548
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F6-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Chromosome 2q37 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K88494268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08682
EP300	ENCODE Transcription Factor Targets	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27626
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04066
BRD-K45978015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18016
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41711
COPD - Chronic obstructive pulmonary disease_Bronchial epithelium_GSE3320	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.89049
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83472
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A8LF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89089981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12126
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08526
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69207
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68427
BRD-K14534138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46274
TFEB	ChEA Transcription Factor Targets	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.537637
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323545
MYC	ENCODE Transcription Factor Targets	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
TNKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00775
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134029_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50112
CRCGN009_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6608
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.537287
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0704
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61418
Tuberculosis	GWAS Catalog SNP-Phenotype Associations	1.0	0.129504
CF-55-OA12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326032
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IE-A4EH-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38732
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K74445272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89858
AA-87-EI21_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321149
gallbladder	HPA Tissue Protein Expression Profiles	1.0	2.56144
BRD-K92457070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36104
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14023
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10872
SP2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.882151
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.181729
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08063
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	10.1661
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95084
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CE-10-WA05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224295
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0186
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835224
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70952
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23904
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54447
BRD-K10027041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18334
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56574
IFT172	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552179
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4073
7454_RPL27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.582236
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13589
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856694
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K45318035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29384
BRD-K96075847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43922
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00857
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08137
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GA-77-MH38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267672
GATM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00685821
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-15-EL49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224088
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2328
Rectum adenocarcinoma_READ_TCGA-F5-6863-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.71335
GTEX-QDVJ-1426-SM-48U1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6643
BRD-K04196669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81892
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22877
Lung adenocarcinoma_LUAD_TCGA-44-A4SU-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78648
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K03546460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50541
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301291
BRD-K53619784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37123
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2667
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.907457
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-486-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_pos_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.219531
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985291
GSE212486,GSE212488_2_v_3_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71501826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16275
BRD-K99727034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1976
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47773
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50364
Aspartate carbamoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49415
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8535
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957285
NB5	DepMap CRISPR Gene Dependency	1.0	3.32892
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hyphal cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
Bed nuclei of the stria terminalis, posterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06056
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28729
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05346
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41988
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76599
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845273
Lateral dorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07496
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62738
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94183
jf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.87995
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.51792
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-1226-SM-48FCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962785
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14387
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06313
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15187
all	GWASdb SNP-Phenotype Associations	1.0	0.034272
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55347
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.62086
BRD-K93519076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4411
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-Hela_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52541
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03366
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55836749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07162
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07667606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77071
BRD-K58041870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38973
ATF2	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3971
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33434
Parabrachial nucleus, lateral division, central lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12688
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.67013
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56512
Cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
valproic acid-347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.570865
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31824
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05392
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.639371
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.45606
BRD-K36176133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6253
neuropeptide-S nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11151
SAS acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.871
vitamin c_mus musculus_gpl1261_gse37676	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56595246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11138
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869007
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6183
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07723
RF-58-GQ76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204971
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.867611
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73286847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13262
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
BRD-K76415727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14392
VE-46-XV53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242988
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495027
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16825
BRD-K85851814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60862
BRD-K79299080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24964
Testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K55459289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8011
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ifosfamide-5805	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QMRM-1126-SM-447BN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893911
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.08625
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UM-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0966
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3299
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A5RQ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RA-49-ZB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.477772
BRD-K27726273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21283
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.928218
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953262
TGFBR2_knockout_294_GSE36778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.57189
hsa-miR-4741	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30007
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910305
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53151
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FF-54-JC89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271681
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01019
AIFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1879
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54274
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49932469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20385
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.683493
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16224
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28812
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
lung	HPA Tissue Gene Expression Profiles	1.0	1.21939
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6770-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074021
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27271
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K66735566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42921
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MPZL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24589
GSE182680,GSE182683_5_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37165790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08563
GTEx Skin 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-6.89035
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69073616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04325
RA-49-ZB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235801
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04522
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852696
GSE129370_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5435-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56799639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21995
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9438
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.93767
RUNX3	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL148	CCLE Cell Line Gene Expression Profiles	1.0	2.3401
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1004
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38484
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K45569026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24664
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281695
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4855
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.727554
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RC-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AG-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2203_DHX15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.634071
mesangium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-4492	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K55638368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12811
BRD-K83946740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42013
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18972
BRD-K36782804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08524
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.25003
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09007
IRF3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6484770-41388_2018_602_MOESM5_ESM.xlsx-up_P53_vs_con-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16104
NCO2	DepMap CRISPR Gene Dependency	1.0	6.45105
BRD-K95537020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3985
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-4430	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06236
BRD-K77609086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12489
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33485
BRD-K62219570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01108
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10937
Acn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
GTEX-SNOS-0826-SM-4DM5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57196
BF-51-OI57_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232114
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10586
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10098
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42469
6-bromoindirubin-3'-oxime-7101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GNB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3535
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.973563
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03918
BRD-K66401298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3937
hsa-miR-4660	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27089
inferior temporal gyrus, right, bank of mts	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11424
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26171
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A7I0-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.75926
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.960375
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0458
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K37276417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48015
GTEx BloodVessel 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-8.97236
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bacterial infectious disease	GWASdb SNP-Disease Associations	1.0	0.338117
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04463
HCV JFH-1_12Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.4958
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.660037
BRD-K72533381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55117
BRD-K84606053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21975
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
histone acetyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32313
Lung squamous cell carcinoma_LUSC_TCGA-77-6843-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0339
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03273
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
ARMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05756
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895504
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.52989
dorsolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48226
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.064557
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Scheuermann's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.109
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37013
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2502
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
PMC9686236-41598_2022_24611_MOESM1_ESM.xlsx-Suppl_Table_10-Supplemental_Table_10_Significant_genes_in_MR_analyses_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CAF-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.525166
BRD-K21327356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34088
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7	BioGPS Cell Line Gene Expression Profiles	1.0	1.5136
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965605
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2126
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09013
organelle organization	GO Biological Process Annotations 2015	1.0	null
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0195
KDM5A	ENCODE Transcription Factor Targets	1.0	null
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39622
hsa-miR-3139	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301724
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.961358
pb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
BRD-K83832060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1123
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
Golgi membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.867818
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922721
Lung squamous cell carcinoma_LUSC_TCGA-85-6798-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS1034	DepMap CRISPR Gene Dependency	1.0	2.98415
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4639
Actin filament	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
RAD21	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51713
IC-80-CT90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229315
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11673
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880347
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827841
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50703
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71574401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31343
BRD-K34425773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21185
MALME3M	CCLE Cell Line Gene Expression Profiles	1.0	1.60784
BRD-K43186783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21705
GGCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49143
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0741
bexarotene_homo sapiens_gpl96_gds2777	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EJM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82797
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309402
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837352
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26694226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04465
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03553
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.798143
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41742
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
8856_TFR2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.685433
internal protein amino acid acetylation	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A1NK-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2757
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2223
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50761
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11839
Lung adenocarcinoma_LUAD_TCGA-69-7980-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5522
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.84878
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06876397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31132
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2637
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61865
golgi membrane	GO Cellular Component Annotations 2015	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.88434
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37524
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67396
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64979
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Coenzyme A	HMDB Metabolites of Enzymes	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37062347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36752
KMS11	CCLE Cell Line Gene Expression Profiles	1.0	3.00535
PMC12079334-ADVS-12-2501734-s002.pdf-154-ENSG00000006194_ZNF263	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51862
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14586
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39454
protein homodimerization activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K29903249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83275
BRD-K86623758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48438
BRD-K19435356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82891
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.19767
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50399
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hela	HPA Cell Line Gene Expression Profiles	1.0	0.838135
EF-52-ML96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374811
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2281
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06034
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36379
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835008
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08244
HC-95-WQ65_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.291665
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914908
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03987
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47510632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04514
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839984
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23266
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26432
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5360-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39526
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	0.94385
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939822
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6786
NCIH2405	CCLE Cell Line Gene CNV Profiles	1.0	1.70394
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.06016
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44344
RSV_24Hour_19459069_GSE3397	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.87098
BRD-K19691332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34757
BRD-A07952294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72282
BRD-K16357911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09416
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09269
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
n-terminal protein amino acid modification	GO Biological Process Annotations 2015	1.0	null
GSE178255_3_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836759
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01215
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02392
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.935799
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.368467
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70791360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69955
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44655
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.074685
CRCGN017_MCF10A.TP53.M_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06983
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03916
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.333
nterminal	GeneRIF Biological Term Annotations	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6343-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86005
Kidney Chromophobe_KICH_TCGA-KL-8336-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
peptide alpha-N-acetyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
8996_TMEM129_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.522191
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27535
renal glomerulus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.22503
4954_MED31_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.72763
BRD-K22475995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18803
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35897
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44817
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16551
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.70347
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6776-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45472595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4104
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870685
BRD-K53127464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3406
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.3769
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55158
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56986
knee	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.881204
SD-69-QA40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.473919
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2767
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Amastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852705
BRD-K39223685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31849
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.54414
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
higher	GeneRIF Biological Term Annotations	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40687
BRD-K70558130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87205
BRD-K43981353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28007
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182835,GSE182836_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20397
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.070425
BRD-K41102088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67202
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SNRK_overexpression_127_GSE30185	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.24363
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
other	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03726
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29513
BRD-K91354770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04934
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K72183943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08648
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E6-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941364
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03898
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255549
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
RMUGS	CCLE Cell Line Gene Expression Profiles	1.0	1.59708
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29828
hsa-miR-4448	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37938
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952559
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.889787
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162276_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rixosome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233344
KASUMI1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54688
cellular macromolecular complex assembly	GO Biological Process Annotations 2015	1.0	null
Urothelial carcinoma_Urothelium_GSE3167	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.608
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10347
BRD-K58242935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2876
8305C cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.971216
BRD-K76997656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3232
BRD-K56283394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07166
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41833
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4317
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K43889095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30077
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
recurrent bacterial infections	GWASdb SNP-Phenotype Associations	1.0	0.410331
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03339
hsa-miR-1301	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
GSE166317_3_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.3232
melanogaster	GeneRIF Biological Term Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22502
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34182
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47536
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rpmi8226	HPA Cell Line Gene Expression Profiles	1.0	0.998018
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20318
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34489
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955831
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33154
Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32402344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01437
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
6708_PPWD1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.586507
Eosinophil percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
RAD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06233
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82367
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09931
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K19755525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09355
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13866
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ND-36-VC68_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259339
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0606
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13324
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1651	CCLE Cell Line Gene Expression Profiles	1.0	2.1175
UPCISCC116	DepMap CRISPR Gene Dependency	1.0	2.16559
BRD-K24292260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78118
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecular complex assembly	GO Biological Process Annotations 2015	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61269
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32120119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01787
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11515
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911233
hsa-miR-4303	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09731
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.880244
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86404
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253127
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4767	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC7576810-41419_2020_3099_MOESM9_ESM.xlsx-MS_analysis_EVI1-WT_vs_EVI1-S43-Unnamed_0_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05542
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62654
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36909
BRD-K16154498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08145
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845273
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887413
hsa-miR-2861	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
hsa-miR-141	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
PMC10881685-Data_Sheet_5.CSV--CASZ1_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872802
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14445
HCV JFH1_120Hour-Huh7_5_1_None_GSE29889	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.756
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.05332
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260433
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928106
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13848
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24965236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98714
DB-42-PI54_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215971
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21735
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91516693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41417
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.292018
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938495
primary bacterial infectious disease	GWASdb SNP-Disease Associations	1.0	0.425585
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07494
BRD-K94247332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36096
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03087
BRD-K06208179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07774
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1425
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07555
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06222
hsa-miR-599	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-0926-SM-3P5ZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941198
U87	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.51438
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE130715_2_v_3_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
n-terminal protein amino acid acetylation	GO Biological Process Annotations 2015	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42513
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.902396
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-16-OE34_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205492
irf1_17409403_nih3t3_gof_mouse_gpl81_gds2752	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.38236
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1296
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942476
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.02336
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMARCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1835
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34561
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1385
BRD-K15876355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97468
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10754
BRD-K16966765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28035
hsa-miR-4421	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.557662
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9588
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intralaminar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15561
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5225
chr16_3458012_A_C_b38	GTEx eQTL 2025	1.0	3.14637
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298101
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4737	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
segregation	GeneRIF Biological Term Annotations	1.0	null
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K79547691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80925
CRCGN015_MCF10A.WT.HP_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3236
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35659
BRD-K22173206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14931
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5U8-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.755664
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.32739
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10696228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1269
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39094
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.82831
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
pancreas	HPA Tissue Protein Expression Profiles	-1.0	-1.41197
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180789_1_v_0_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4145
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.41197
BRD-K30358777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04963
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40921
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.364
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297655
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GJB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484688
NCIH1563	CCLE Cell Line Gene Expression Profiles	1.0	2.14177
VPS4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10074
UA-39-TN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3804
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.71467
BRD-K62504352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06821
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.43619
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
protein acetylation	GO Biological Process Annotations 2023	1.0	null
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42368
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955831
5964_LTO1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.873598
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K10925833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34147
HSPB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18014
KSR1_knockout_126_GSE28228	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.36504
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27758
protein acetylation	GO Biological Process Annotations 2015	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
n-acetyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31780647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25776
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15326
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
Polymeric cytoskeletal fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266684
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1202
SD-69-QA40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303511
AA-50-HR61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329402
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1842
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29546
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Enterovirus 71_8Hour_None_GSE15323	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.21903
BRD-K70844489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44473
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23422
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7995-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32299
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Smooth endoplasmic reticulum cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.387
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1162
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33184
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TEAD4	ChEA Transcription Factor Targets	1.0	null
BRD-K96491664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28626
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95219
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980419
bounding membrane of organelle	GO Cellular Component Annotations 2023	1.0	null
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84715
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.898563
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.291132
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23836
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K90762344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1896
CAKI2	CCLE Cell Line Gene CNV Profiles	1.0	1.49762
SCA1_Knock-in_GDS1756_233_mouse_Forebrain tissue - 4 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15256
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	2.56268
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0583
GSE150072,GSE169209_6_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877536
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92906
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83412
Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91569
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03693
hsa-miR-1184	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48977
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58021
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09017
BRD-K95048194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08202
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81515704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15611
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4651_LRP8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.668699
BRD-K64268886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33065
GSE146253_0_v_5_stat4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PPARA_KO_GDS3748_516_mouse_Livers	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0151
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169571
BRD-K05992469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19124
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1-26981420-C2C12-MOUSE-MUSCLE	ChEA Transcription Factor Targets 2022	1.0	null
SLTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.88542
BRD-K29502299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36712
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43072
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41334119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34567
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
VMRCRCW	CCLE Cell Line Gene CNV Profiles	1.0	1.57269
BRD-K20142115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13121
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.028
BRD-K39592958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01713
DA-10-HD17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.477998
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.454368
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.00152
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16295
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
beta-galactosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
BRD-K20501114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68895
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.855704
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.356171
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88602
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229796
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30638
CRCGN016_MCF10A.WT.HP_24H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45535
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11139
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.064
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892603
cell proliferation	GO Biological Process Annotations 2015	1.0	null
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
HCC56	CCLE Cell Line Gene Expression Profiles	1.0	1.47343
GSE70499_5_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25171
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01837
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
chromosomal	GeneRIF Biological Term Annotations	1.0	null
Anaplasmosis_Leukemic Cell_GSE2600	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	3.07027
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42192
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Midbrain, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08054
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K45859834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29345
NUDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03012
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K30252238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58363
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05219
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04577
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14151
pimosertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10255
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
NatC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.184
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866205
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21571
JMSU1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50894
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K10241968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46795
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7602
renal corpuscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HDMYZ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18445
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836662
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.36307
BRD-K49945344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.432
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38345
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13988
BRD-K13792178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1241
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7302
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8229_SNRPD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.668041
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2038
n-terminal peptidyl-methionine acetylation	GO Biological Process Annotations 2015	1.0	null
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
complexity	GeneRIF Biological Term Annotations	1.0	null
BRD-K53971345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16099
Ogden syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.512
a549	HPA Cell Line Gene Expression Profiles	1.0	0.870497
mesangial cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12867546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05292
mitral valve insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.994439
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04122
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76631
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927118
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.958685
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
COLO684	DepMap CRISPR Gene Dependency	1.0	2.13198
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042185
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
BRD-K06926365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55413
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
optic fiber layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0593
BRD-K73680186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57952
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.338146
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863108
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81982648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04156
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.3058
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867319
a431	HPA Cell Line Gene Expression Profiles	-1.0	-1.07805
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.9607
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10636
COLO205	DepMap CRISPR Gene Dependency	1.0	7.71934
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
histone acetylation	GO Biological Process Annotations 2023	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62051
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LM4_M2	MotifMap Predicted Transcription Factor Targets	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984495
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868201
protein acetylation	GO Biological Process Annotations 2025	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KC-17-YN77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300228
BRD-K75576005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30911
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.66018
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28339544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54186
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867319
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49595
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.98504
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13259
Filippi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Syndromic microphthalmia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.186
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11328671-jitc-12-4-s003.pdf-275-MYT1L_MYT1L	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99939085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75768
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57385
GATA1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054616
MKN45	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54421
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993168
BATF	ENCODE Transcription Factor Targets	1.0	null
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4181
BRD-K83875224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36904
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35595
hsa-miR-4717-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
NFYA	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4763-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.981449
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.298
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42908
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6628
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04389
GSE162276_4_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69081
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2819
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01573
7504_RPS15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.766696
recurrent mycobacterium avium complex infections	GWASdb SNP-Phenotype Associations	1.0	0.969142
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-1526-SM-3P61M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94388
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870455
BRD-K58025976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33976
teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K11812419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00427
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830319
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226049
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54283
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4373
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838957
BRD-K24502602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04166
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06648
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.830759
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE182854_2_v_3_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867319
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35639
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.92282
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23692
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94187
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12634
BRD-K47998973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18755
BRD-K79635719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17978
RP1_KO_GDS1845_190_mouse_Retinas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein-DNA complex assembly	GO Biological Process Annotations 2025	1.0	null
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.58481
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-10a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56062
mitral valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.818796
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00341
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82126187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38658
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parabrachial complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03366
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830319
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839994
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33618
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47975
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0997
CRCGN017_MCF10A.TP53.M_24H:D22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78933
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128333_2_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33245
FU97	CCLE Cell Line Gene Expression Profiles	1.0	2.30342
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13099
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.85911
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11986
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.12608
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.28283
Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32834
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1988
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K22508525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0881
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.418
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37882
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63828
BRD-K73001304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35992
BRD-K23543737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27128
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01887
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUPM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59405
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201356
Cerebral amyloid deposition (PET imaging)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54447
GSE162276_4_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mitotic arrest phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K24479270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03288
BRD-K63920153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29485
COLO775	CCLE Cell Line Gene Expression Profiles	1.0	1.74525
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06849
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1067
BICR22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16361
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42866
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00668
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858145
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19528
nucleosome assembly	GO Biological Process Annotations 2015	1.0	null
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-59-HG56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249096
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22588
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51849151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70412
BRD-K26195700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2193
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KAT2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184884_7_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hypospadias	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
A498	CCLE Cell Line Gene Expression Profiles	1.0	1.38066
Locus ceruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00668
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09285
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0134
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24651
BRD-K06475437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46179
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865771
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.788141
BRD-K58596567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01777
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50112
BRD-K68953461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9849
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1379
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8972
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27273
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3361
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32806
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10784
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.11271
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79725
EZH2	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6329
BRD-K12240312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10136
17234769-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
Blood Pressure	dbGAP Gene-Trait Associations	1.0	0.252671
Ewing's sarcoma_Renal Tissue_GSE1822	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.68164
GLI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37304
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SYNCRIP_OE_GDS3186_84_mouse_wild type 129 mouse retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.961458
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.6397
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07691
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15795
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19676
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06674
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr16_3451656_A_G_b38	GTEx eQTL 2025	1.0	1.04126
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04641
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60571
GTEX-XUJ4-1226-SM-4BOPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89638
BRD-K56119660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53123
BRD-K18984088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21768
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867319
hsa-miR-4253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.22948
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.83
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.38189
BRD-K22481359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07776
protein complex assembly	GO Biological Process Annotations 2015	1.0	null
NCI-SNU-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K24387453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36885
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
TCF21-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918994
PMC5263239-mmc2.xls-SEM_wt_MLL-Gene_name_1614_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
PIGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19714
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K82284644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31593
mcf7	HPA Cell Line Gene Expression Profiles	1.0	2.38373
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15667
ALK_druginhibition_187_GSE50803	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.79411
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85921
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07912
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02779
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20259
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.1397
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51893
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63837
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14538
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23887
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03743
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.75514
BRD-K35369722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22043
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.942153
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0606
BRD-K01754917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.306
BRD-K97421379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11311
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06984
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
BRD-K37398853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41499
BRD-K45734531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40311
SLR25	CCLE Cell Line Gene CNV Profiles	1.0	1.99293
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.78015
BRD-K92712225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68394
SYT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89108
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228729
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AC-51-WE57_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.596685
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283198
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06376
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61071
19843711-TableS2	GeneSigDB Published Gene Signatures	1.0	null
medial parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12942
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.32643
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50436
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881894
GSE224157_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
Acyl-CoA N-acyltransferase	InterPro Predicted Protein Domain Annotations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46368
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28462
Lung adenocarcinoma_LUAD_TCGA-50-5944-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31638
BRD-K11476310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00812
BRD-K55538850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53951
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01259
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31437957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39637
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.77084
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bloodstream form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.82697
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3179	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12672
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57666
SYK_knockdown_191_GSE54065	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.14389
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-23-HP88_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207306
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.08343
skin	HPA Tissue Gene Expression Profiles	-1.0	-0.992652
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Golgi membrane	GO Cellular Component Annotations 2023	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.846405
BRD-K97348029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20129
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80527
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17555561-Table1	GeneSigDB Published Gene Signatures	1.0	null
IFNA10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00427518
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.29159
GTEX-WI4N-1126-SM-3LK7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855798
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.9548
PML	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867319
CRCGN015_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01472
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48758
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24657
Chloroplast thylakoid membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36167
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235393
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.968325
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04123
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47S-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8222_SNRNP70_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.504141
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04381
hsa-miR-3180-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MLL1/2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
GTEX-NFK9-1526-SM-3LK7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28781
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979031
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN015_MCF10A_48H:F12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04789
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.25
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.851833
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05775
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37756
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
DA-59-ZD74_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20151
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65717
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K68379391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1372
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07928699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54358
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27757
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03206
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77958314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61516
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56071
BRD-K44908610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49135
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51237
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K05411364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13685
BRD-K59030325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63626
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.873
Lung adenocarcinoma_LUAD_TCGA-91-6836-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDA1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
drosophila	GeneRIF Biological Term Annotations	1.0	null
BRD-K54247106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37955
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	1.05841
BRD-K80467627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08073
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00331
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59108
skmel30	HPA Cell Line Gene Expression Profiles	-1.0	-0.887608
BRD-K97064059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07533
BRD-K72468471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27939
RUNX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598241
valproic acid-346	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-let-7e-5p	MiRTarBase microRNA Targets	1.0	null
SMARCA4	ChEA Transcription Factor Targets	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K54657536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10279
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.9372
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43012
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.916171
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Eosinophil count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91655
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17309
BRD-A03997826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11799
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77184
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OB-06-WW76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327755
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2751
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06382
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.757616
peptidyl-lysine acetylation	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YI-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0182
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840295
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE2779	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.38996
HCV JFH1_168Hour-Huh7_None_GSE29889	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.667
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FU-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229468,GSE229471_0_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0606
BRD-K71472853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50494
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20203
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06378
BRD-K69453266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82793
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.9415
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K43594798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27321
sub-surface cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.398
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31762
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67867
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05803
BRD-K36583698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2631
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55782
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.97003
acetyl-coa:l-lysine n6-acetyltransferase	GO Molecular Function Annotations 2015	1.0	null
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14521
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.11677
Kidney Chromophobe_KICH_TCGA-KO-8414-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04264
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.620321
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932886
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79592
BRD-K58140298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04413
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18368
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14211
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48338
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ER-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3158
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19297
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65693
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57543
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
D-245MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VMCUB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83891
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.848933
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859206
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0452
PMC8410861-41467_2021_25544_MOESM34_ESM.xlsx-MCR-geneID_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
Viral cardiomyopathy_Myocardial tissue_GSE4172	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.79016
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26682
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	2.01508
SARS-CoV_84Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69054
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63964208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24966
Lung adenocarcinoma_LUAD_TCGA-93-7348-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30036
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.00986
BRD-K11545984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39335
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225292
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34360192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48148
TCCPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.43581
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K31994521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00361
BRD-K72317601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98671
BRD-K55814495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27174
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.453297
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75905
Lung adenocarcinoma_LUAD_TCGA-J2-A4AG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acetyl-CoA	HMDB Metabolites of Enzymes	1.0	null
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22368
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35474
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31814
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14671
SA-32-CC58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25463
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445042
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.02506
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.49305
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31929
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01068
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12688
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUHR4TKB	DepMap CRISPR Gene Dependency	1.0	2.71015
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rofecoxib-371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5397-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0864
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91889
Acute Myeloid Leukemia_LAML_TCGA-AB-2835-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0951
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980135
BRD-K91500340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66011
HIPK2_knockdown_106_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.80518
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.54653
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZW-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.692965
BRD-K43205312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00632
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZNF662	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17473
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PCI4B	DepMap CRISPR Gene Dependency	1.0	2.69262
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
induced	GeneRIF Biological Term Annotations	1.0	null
BRD-K19580273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09129
GM2313	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08831
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94858
Parabrachial nucleus, lateral division, ventral lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20882
NCS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653606
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0713
BRD-K22485581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36321
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0574
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22510845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09436
BRD-K11457257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0796
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-WL-A834-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158434
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.480273
EF-92-OO68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387023
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07974
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.487589
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71241
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204814
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFI30	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00498661
BRD-K71216961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46959
BRD-K91399333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04306
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28451
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.246
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WEY5-1226-SM-4LMIQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21833
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31538
BRD-K70533557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34639
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90108
BRD-K44760023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81854
H3K79me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K53447551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11442
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08721
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73695595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06607
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19473
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65823297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12301
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87857
BRD-K98169006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12946
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236627
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.475812
N-terminal protein amino acid acetylation	GO Biological Process Annotations 2023	1.0	null
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01743
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22565
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K99470595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47431
BRD-K45042519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01293
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
KNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32435
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14551
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920242
BRD-K40117723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17563
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3191	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4492	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09627
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23194
FOS	ENCODE Transcription Factor Targets	1.0	null
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0249
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09735
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.734921
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858516
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03663
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
BRD-K05135707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09862
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955863
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09149
BRD-K99581286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81414
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_YY1_21170310	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13866
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03783
Brain Lower Grade Glioma_LGG_TCGA-DU-7301-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.644
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.866864
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18776
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58146
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.994268
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.606828
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07289
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE193624_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.1948
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.55745
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.14674
GSE211177,GSE211178_8_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Trophoblast stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333062
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.367502
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877536
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.86769
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33498
RH18	CCLE Cell Line Gene CNV Profiles	1.0	2.36979
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BA-39-HG26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242763
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17332
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71007902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41442
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.66416
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38687
Lung adenocarcinoma_LUAD_TCGA-MP-A4SW-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49987
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K52685199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79234
Gestational trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18499
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2025	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.9126
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49162
n-acyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K42987166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05447
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939631
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09415
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	1.0	3.18267
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0626-SM-4DM6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30021
DA-49-ZD74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221326
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.938204
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35917
16498405-TableS4	GeneSigDB Published Gene Signatures	1.0	null
BRD-K02061146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1013
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.68814
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.07354
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67228
CDK9_druginhibition_183_GSE48258	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.164387
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59283
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
1464_CDYL_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.964869
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.036027
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46155
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0232
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromatin modification	GO Biological Process Annotations 2015	1.0	null
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328994
BRD-K89935890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55583
KRAP_Deficiency_GDS3528_564_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932983
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08812
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.975088
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40358
BRD-K00744507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53764
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8747
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2599
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34717
BRD-A57536034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73067
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053576
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49177
disease by infectious agent	GWASdb SNP-Disease Associations	1.0	0.176029
BRD-K85456301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38516
BRD-K79433629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21935
SCN4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05188
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.99859
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6408
NCIH1915	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88983
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE181521_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62558
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58628
HIV - Human immunodeficiency virus infection_T lymphocyte_GSE2504	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.06358
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25458
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.60577
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-1.78602
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.072105
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13038935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5154
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34548
NCIH2347	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59986
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36698
BRD-K76812105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07823
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
acetyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-28-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.851183
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Supramolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
furan	CTD Gene-Chemical Interactions	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04971
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26748243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3889
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06525
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0482
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75479
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76093
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94772
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21211
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
U343	DepMap CRISPR Gene Dependency	1.0	2.68354
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08877
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
4019_ID2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.516202
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70537701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85734
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81078
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03863
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K43292469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10736
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02436
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21406
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AB-01B-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56618252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68855
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4527
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75317
Double outlet right ventricle	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18133
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2297
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15056
BRD-K70109334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56219
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.22785
BRD-K56086519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0021
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25332
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45665532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02347
biological_process	GO Biological Process Annotations 2015	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X0-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11674021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1706
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218319
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WASHC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60736
U87MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94911
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
b21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849085
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50326
BRD-K03476091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47991
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVMANA	DepMap CRISPR Gene Dependency	1.0	2.89944
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.25784
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05204
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.50036
GSE87299_2_v_3_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.00894
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273899
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.405615
Lung squamous cell carcinoma_LUSC_TCGA-56-5898-01A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910235
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17316_KO_Tardbp_SRP321767	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.6804
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21529
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
SUDHL10	DepMap CRISPR Gene Dependency	1.0	2.55578
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.562497
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40612
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26603
BRD-K74486924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25067
MAMSTR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00486004
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AK5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K14732815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16894
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.92935
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62681
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.865506
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1879
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.964858
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.755664
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.872195
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NatA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.122
CRCGN015_MCF10A_48H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06985
anterior nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79242
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AC-43-ZC52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228399
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053575
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937828
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
NCIH650	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97418
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4551
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11999
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10959
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach	GTEx Tissue Gene Expression Profiles	1.0	1.17668
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.058
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organization	GeneRIF Biological Term Annotations	1.0	null
BRD-K11979048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22631
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.355974
FOXM1-32153563-SKOV3-HUMAN-OVARY-OVARIANCANCER	ChEA Transcription Factor Targets 2022	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88719
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911546
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50494
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90134
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11564
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07482
chr16_3480674_T_TTGGGAGGCCCAGG_b38	GTEx eQTL 2025	1.0	1.56235
FC-68-LJ11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330471
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
quadriceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.633144
BRD-K54332342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63339
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0078
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TT2609C02	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38116
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46317
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90374
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26467
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23344
dydrogesterone-2156	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF7L	ChEA Transcription Factor Targets	1.0	null
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Epimastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
BRD-K96776591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0516
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13624
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63633
PAX5	ENCODE Transcription Factor Targets	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7823-01B-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndromic microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.841
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939669
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947014
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.727
HEPG2	BioGPS Cell Line Gene Expression Profiles	1.0	1.30224
BRD-K82187446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2961
GSE167224,GSE168147_1_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.05913
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46409
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64376499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38384
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6511
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10754
Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7626
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE117643_1_v_0_irx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88190816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80563
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67606
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.42124
Parabrachial nucleus, lateral division, dorsal lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59375
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.24562
4540_LDB1_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.623123
TFAP2C	ChEA Transcription Factor Targets	1.0	null
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.509
SIRT6	ENCODE Transcription Factor Targets	1.0	null
AA-45-AA67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217389
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.832081
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	1.37118
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUGC2	CCLE Cell Line Gene Expression Profiles	1.0	1.41044
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3145-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27823
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.129
BRD-K11757577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14631
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JEKO1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.34787
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18639
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.912205
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein-dna complex assembly	GO Biological Process Annotations 2015	1.0	null
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12111
DB-62-ES23_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34141
GTEX-QXCU-1926-SM-48FE4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31785
BRD-K19573822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38045
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14645
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14279
disease	GWASdb SNP-Disease Associations	1.0	0.034202
BRD-K79020643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1437
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.851366
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16345
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833344
NH12	DepMap CRISPR Gene Dependency	1.0	2.03911
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A460-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.5962
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86409
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969871
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
PMC9164515-5-12-22-eQTL_Supplemental_tables_ScientificReport.xlsx-Suppl_Table_8-Supplemental_Table_8_Significant_genes_in_MR_analyses_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
D502MG	DepMap CRISPR Gene Dependency	1.0	10.9646
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15889
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00012
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11036
5731_NOC4L_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.500279
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9781
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51571
BRD-K67200393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25781
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.982034
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.947341
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27799
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.78719
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10307
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924673
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:H20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08647
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33149
BRD-K77177732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00951
N-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.093
Perturb_11276_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904367
BRD-K47098496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00865
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14976
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.68819
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06662
TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
MTMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17542
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K26631178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08747
CRCGN015_MCF10A_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1401
BRD-K32879108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04349
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20866
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86648
BRD-A68913459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35409
mantle zone of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15759
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
BA-77-US35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.684656
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04369
BRD-K27229533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28361
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K80210288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50394
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75243062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06479
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980456
GTEX-S4Q7-0726-SM-4AD5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77911
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860234
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61898
MAP1S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21589
acetyltransferase	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952198
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RG-A7D4-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8466
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08877
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908517
NCIH2347	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40572
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1587	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7518_KD_TRDMT1_SRP217219	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.9676
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
histone H4 acetyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K56520977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50529
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3182
hsa-miR-4638-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
BRD-K95501793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27785
BRD-K52341452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93644
protein-DNA complex assembly	GO Biological Process Annotations 2023	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47192
GTEX-OHPN-2726-SM-2I5H4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957848
fibromyalgia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.862228
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60502
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	1.0	3.12316
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K57323824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.103
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.437972
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835573
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-59-RG09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.49747
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17352
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03243
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2995
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38650960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33854
UA-39-TN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.376119
Chromosome 16p12.2-p11.2 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4698
Lung squamous cell carcinoma_LUSC_TCGA-56-A4ZK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30782
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0478
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38356
IF-31-BQ95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245241
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12015168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02855
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.13209
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12709183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72366
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01127
Overexertion_Leukocyte_GSE3606	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.47806
Visceral leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838738
hsa-miR-1587	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10225
TAF7L-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.991987
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0482
Leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.929
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829699
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
OGFOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35415
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15357
Mediodorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50827
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	2.14361
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57415
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.97296
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6651
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.71338
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-1526-SM-48TDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41485
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97155
HOXC9	ChEA Transcription Factor Targets	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.52308
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEx Nerve 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-7.95392
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9265
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.916131
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1081-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35142
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.57233
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980135
PRXL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46451
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937651
hsa-miR-200a	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8508
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07065
Necrosis	CTD Gene-Disease Associations	1.0	1.32637
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
peptide n-acetyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89032,GSE89033_0_v_1_sfpq_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884188
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16561
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854023
BRD-K81999794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91167
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918105
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-46-GL76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200861
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
CRCGN015_HEPG2_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53883
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839682
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849695
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S95S-0826-SM-4B64N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26854
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82251
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14645
defined	GeneRIF Biological Term Annotations	1.0	null
RA-49-ZB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2702
Elagolix sodium_A-172	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00680155
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.291276
chr16_3462662_G_C_b38	GTEx eQTL 2025	1.0	1.67874
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.934721
HEC251	DepMap CRISPR Gene Dependency	1.0	2.01074
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.74854
BRD-K54837058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04693
IRF3	ENCODE Transcription Factor Targets	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.36763
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59987
S0-EE-U3YG_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2551
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K19381111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60949
heart valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.58433
NC-52-HX69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207047
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256172
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51783
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26273412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76729
CRCGN017_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05635
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28154
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.800481
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21361
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12094
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15759
Neurosphere_Cultured_Cells_Cortex_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.979764
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74991
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269384
Idiosyncratic drug effect_Hepatic Tissue_GSE2825	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.12931
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30969
hsa-miR-762	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
hsa-miR-922	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.429567
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peptidyl-lysine modification	GO Biological Process Annotations 2015	1.0	null
BRD-K58756877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29075
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851667
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.869704
superficial gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1543
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.86405
Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC364	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82964
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2699
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14733
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24827
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15099225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04814
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4466	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
acetylate	GeneRIF Biological Term Annotations	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
BRD-K57972271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01392
BRD-K43989220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33441
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.685023
tuberculosis	GWASdb SNP-Disease Associations	1.0	1.10764
SNU668	CCLE Cell Line Gene Expression Profiles	1.0	1.35946
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0482
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K86467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9423
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K23956364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82733
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.16548
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87113
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38215
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.78193
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0471
MAP3K7_knockdown_37_GDS5023	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.09022
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0668
STAT5A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62768
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63748
H3K36me3_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03696
hsa-miR-421	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
NCIH1048	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75231
CC-15-MK46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286874
BRD-K17441474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10998
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.039
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60105
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69028
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29235
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938899
Kagami-Ogata syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25031
MVB12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51279
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
protein maturation	GO Biological Process Annotations 2023	1.0	null
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
player	GeneRIF Biological Term Annotations	1.0	null
PKBalpha_KO_GDS1784_193_mouse_Embryonic fibroblasts (MEFs) - 0 hour	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02637850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61459
BRD-K12866026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55832
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.95985
GTEX-PX3G-1526-SM-48U11	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13728
GSE90754_0_v_1_foxo1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-378g	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
BRD-K13817284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14846
Renal glomerulus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intermediate stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13073
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0385
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cysteine synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65051
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K91191855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05587
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3132
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11105500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29733
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K24108193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3298
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.812452
BRD-K89701103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77595
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04155570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81669
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84069
Cystocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.987285
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.08035
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.508818
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
contribute	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3967
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13844
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7048
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02448
BRD-K32882942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08335
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07683
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07447
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28462
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.865716
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934428
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A05422420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05667
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15351
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941648
protein homodimerization activity	GO Molecular Function Annotations 2025	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PC-68-DU31_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237339
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0045
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46843
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849081
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03065
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6622-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41023
GTEX-WOFL-0626-SM-3MJG3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07801
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5369
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19957
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26843
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94082609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18178
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7915
BRD-K31546068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05223
DA-10-HD17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232544
BRD-A27422067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2247
RFX5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11123
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2037
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.533044
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831176
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4726-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1505
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.8491
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75905
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2088
PMC12585103-pbio.3003444.s013.xlsx-List_of_genes_for_GO_analysis-List_of_genes_undergoing_significant_MXE_upon_PRMT5_KD_under_hypoxia_AR	Rummagene Transcription Factor Associations 2026	1.0	null
femur	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477367
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.705298
Prostate adenocarcinoma_PRAD_TCGA-HI-7171-01A-12R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26454
UF-14-LK87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307597
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29407
MAGEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12774
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11673
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188721_2_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.640208
hsa-miR-4514	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867319
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.587272
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Chloroplast thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07938
BA-59-EN38_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.449928
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.45678
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34127
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045529
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.841815
N-acetylmuramic acid-3262	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98305
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9556
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE206400_1_v_4_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K86750448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07878
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LGLL - Large granular lymphocytic leukemia_Peripheral blood mononuclear cell_GSE10631	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49844
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LB-90-DC89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330063
BRD-K37507671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43901
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86697
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.949635
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06841
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47643
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48119
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60648
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
3986_HSPE1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.599429
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91205
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28937085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42714
nucleosome assembly	GO Biological Process Annotations 2023	1.0	null
Mesangial cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K70935154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24779
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08809
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890701
PCI15A	DepMap CRISPR Gene Dependency	1.0	2.19493
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.964858
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.098
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.543734
Brain Lower Grade Glioma_LGG_TCGA-DH-5141-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85525164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16652
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36592
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910647
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28497
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55273
BRD-K04251837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70712
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EW7	DepMap CRISPR Gene Dependency	1.0	2.09924
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86988191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31243
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basomedial amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05699
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5629
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14791
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16612
NCIH209	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47891
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62643
BRD-K19710723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38849
hsa-miR-3151	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8778
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980135
hsa-miR-1914	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.82679
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein-N-terminal amino-acid acetyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
phenylalanine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
non-syndromic intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18303
BRD-K68060538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59999
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29277
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06393
GTEX-X4XY-0926-SM-4E3JD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867537
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21826
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K88189489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02899
Lung squamous cell carcinoma_LUSC_TCGA-63-A5M9-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8157_SMC3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.61193
BRD-K92349794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86612
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
Familial combined hyperlipidaemia_lymphoblast_GSE1010	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.8044
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17752
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31707
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lansoprazole-2967	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929145
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973364
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.43011
MSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
GTEX-Q734-1026-SM-48U16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51381
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.167664
RUNX1-27514584-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Multilymphoid progenitor cell_Umbilical cord blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898022
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40253
AA-43-BW50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339829
2907_FAM216A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.847641
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58382884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78723
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210353
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202006
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210338
2852_FAM133B_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.723872
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51176
BRD-K35058762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14325
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87857
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE178255_2_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r7 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12618
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.82552
19525976-SuppTable5a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49827
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3782
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17871
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15187
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838497
ACHE_OE_GDS891_241_mouse_Prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-4252	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.498587
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.14479
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4656	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Anterior group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41253
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3561
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01364
Parabrachial nucleus, lateral division, superior lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42628
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
GSE225447_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980135
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.91359
CRCGN014_HEPG2_3H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0008
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38985
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
SLC36A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00695874
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04049
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.17294
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839328
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21789
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
HS746T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
nucleosome assembly	GO Biological Process Annotations 2025	1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57105
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989314
BRD-K24722502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21282
GSE171572_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.20526
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867319
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281292
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19081
hsa-miR-4498	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
N-terminal peptidyl-methionine acetylation	GO Biological Process Annotations 2025	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919293
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34357
transferase activity, transferring acyl groups	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71755682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35914
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61440521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27703
BRD-A61778798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19902
r6 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66914
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13737
BRD-K84439371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22605
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857693
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18989
PPARGC1A_KO_GDS2391_299_mouse_brain striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
MKN7	CCLE Cell Line Gene CNV Profiles	-1.0	-2.85572
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14149
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11848
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35536
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8811
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26294
BRD-K39978929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01724
Fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83682
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.981865
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27357
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13904
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6829
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09598
BRD-K96547094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00572
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
NHLF	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.11216
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K52423731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13997
HS821T	CCLE Cell Line Gene CNV Profiles	1.0	1.41001
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1239
MIF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
ZFAND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07395
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46457
FGFR1_knockdown_94_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.36814
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6863_PSMC6_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.17095
Lung squamous cell carcinoma_LUSC_TCGA-94-8490-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02788568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31368
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02883
Lung adenocarcinoma_LUAD_TCGA-53-7813-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.513947
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
NCIH1092	DepMap CRISPR Gene Dependency	1.0	3.7023
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906209
BRD-K08174111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34958
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.062
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-80-OD07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2134
BRD-A12894472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68087
OF-05-CB18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22212
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848524
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24369860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70567
SW403	CCLE Cell Line Gene CNV Profiles	1.0	1.40559
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cyclophosphamide_mus musculus_gpl13209_gse27423	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI H23	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.841021
BRD-K08355771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24882
SKMEL30	DepMap CRISPR Gene Dependency	1.0	2.71923
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06121
BRD-A52893269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09462
Perturb_11218_KO_MTA2_SRP396801	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.6459
RCOR1	ENCODE Transcription Factor Targets	1.0	null
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52306
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10514
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89505
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92937
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.351115
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
debrisoquine-5288	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
5933_OGT_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.501805
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21831
hsa-miR-4533	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K24133999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00743
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08938
Hypolemmal cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.391
duodenum	HPA Tissue Gene Expression Profiles	1.0	1.77811
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0482
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
N-terminal peptidyl-methionine acetylation	GO Biological Process Annotations 2023	1.0	null
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294806
BRD-K88504000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71294
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70322385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.228
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.41371
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91284
2988_FBL_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.05976
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874123
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50751
Lung squamous cell carcinoma_LUSC_TCGA-34-8456-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.292356
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47713
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.41197
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.1468
single-organism process	GO Biological Process Annotations 2015	1.0	null
fulvestrant-6918	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16682693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95073
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41024
myositis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.55518
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
DD-08-NW42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278471
ID-26-HX79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307595
ID-70-SM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200959
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31647
BRD-K62351887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62866
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87857
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
431_AQR_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.525291
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35312
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4IJ-01A-31R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07932
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54351451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08947
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05262
GNAT domain	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.71475
HC-95-WQ65_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21713
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22269
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.69621
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48811
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81306
MB-49-LL22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329793
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35332
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37601
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-A86415025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95156
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18055
hsa-miR-10b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peptidyl-methionine modification	GO Biological Process Annotations 2023	1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02677
Tuberculosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94524
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57187
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11622
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_5_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0382
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.80628
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54702
BRD-K47988839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14206
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01245
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14484
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	0.850607
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20395
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.938668
Mulchandani-Bhoj-Conlin syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
BRD-K09376533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60155
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ntermini	GeneRIF Biological Term Annotations	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91155
BRD-K84716908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21648
6611_PPAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.515954
VDR	ChEA Transcription Factor Targets	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2759
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04405
BRD-K90526956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38114
YY1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15901_KD_Jun_SRP361315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.1339
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein acylation	GO Biological Process Annotations 2015	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLT1_knockdown_111_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.99547
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11758
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25421
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.36517
BRD-K67830713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37394
Medial group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33062
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K10634221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50607
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.15993
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02384
CHD1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26444
BRD-K05837079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66754
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7542
GTEx Nerve 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-4.24415
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE248874_1_v_0_pcdh9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.693613
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918893
hsa-miR-4753-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
BRD-K57388326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0066
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.961973
BB-44-SX65_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212735
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.945678
GSE249098_1_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88601
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.400891
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2564
colonrectum_f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.5597
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0102
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5400-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
krt7_21596846_megakaryocyte_progenitor_bone_marrow_lof_mouse_gpl6105_gse24969	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.33318
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300576
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0691
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.85867
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911948
BRD-K56658444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17427
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21362
BRD-K58844095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09639
BRD-K73051782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12296
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.33066
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EQ-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48973
hsa-miR-4258	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20548
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87857
BRD-K19962165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50422
Osteochondrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3997
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
PMC10203545-Table_4.xlsx-LM7_underrepresented-DMRTA1_DMRTA1	Rummagene Transcription Factor Associations 2026	1.0	null
nephron	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23108
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61304
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10524
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84692
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30666
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
defects	GeneRIF Biological Term Annotations	1.0	null
Inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24741
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37937
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HUPT4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86935
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26102
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860356
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.866096
Supramolecular polymer	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
BRD-K42960858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42408
Atrial heart septal defect 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980135
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908496
chromosome segregation	GO Biological Process Annotations 2015	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.878339
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162276_4_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32925057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07026
GSE146074_0_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9601
A549_Resveratrol_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161932
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899249
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170054
BRD-K47926785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0235
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952864
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A464-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-10-HD17_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.380292
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90858
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47896
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EOMES	ChEA Transcription Factor Targets	1.0	null
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43478
CDC27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89201
Leukemia, Chronic T-Cell_T lymphocyte_GSE5788	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.88836
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CRCGN009_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27209
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88094
hsa-miR-4653-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07002
DKMG	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25514
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950331
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0393
BRD-K87640319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65726
BRD-K84387578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3963
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3456
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01412
BRD-K09721867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24356
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1177
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18251
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218060_7_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
EE-98-PF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289137
GSE212760_0_v_1_fxr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Chloroplast thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.341272
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09691
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.42005
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913606
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875659
BRD-K31836496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23162
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298458
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11387
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
M/G1 phase-specific MADS box-forkhead transcription factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00321
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UTP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90841
BRD-K15940471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29916
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969121
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867319
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2439
Adrenocortical carcinoma_ACC_TCGA-OR-A5J9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K86070914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05303
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.799669
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K36me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62256869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06574
HUH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58669
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01404
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13264
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.869068
BRD-A59009217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06244
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rubinstein-Taybi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
BRD-K63809385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32446
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49490091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43533
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
J-774A.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.039
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Tracheomalacia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
gemcitabine_homo sapiens_gpl96_gse6914	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22079
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49331
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995503
GSE148066,GSE157787_0_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SAGA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03991
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr16_3461232_G_GT_b38	GTEx eQTL 2025	1.0	1.65996
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.046
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06567
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7854
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31866
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
nucleosome organization	GO Biological Process Annotations 2015	1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29031
Lung squamous cell carcinoma_LUSC_TCGA-79-5596-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87976
NELFE	ENCODE Transcription Factor Targets	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60756
SKMEL24	DepMap CRISPR Gene Dependency	1.0	11.5909
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HAX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586747
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209376
Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204265
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43354
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.590095
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05863
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01491
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN7	CCLE Cell Line Gene Expression Profiles	-1.0	-3.26032
FOXO1_KD_GDS2720_477_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K94441949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16606
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GSE193993_4_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30782
BRD-K71561082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69701
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15444
GSE158834_0_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59153
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887614
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0461
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.755664
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62854
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50213
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
BRD-K10900122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14567
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13697
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052951
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895825
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040616
KAT2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872298
recurrent mycobacterial infections	GWASdb SNP-Phenotype Associations	1.0	0.969142
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32239
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MP-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-708	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4950_MED27_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.530734
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35387
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933209
BRD-K99210277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59637
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49734
MAZ	ENCODE Transcription Factor Targets	1.0	null
KARPAS299	CCLE Cell Line Gene Expression Profiles	1.0	1.3894
GSE102675_2_v_1_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945751
hsa-miR-3921	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
Silver-Russell syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33706
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71742655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31468
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.79643
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30326
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1564
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4432	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08555
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36181
HCC2279	CCLE Cell Line Gene Expression Profiles	1.0	1.85192
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_5_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F4-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1668
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nephron	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7032
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05099
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57955
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F0-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K64640769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17487
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32752
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15825
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
105_ACTG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.817013
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JA-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K91866516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14755
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.84722
golgi apparatus part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07434
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mesangium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70588
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24828
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996124
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A34774643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39891
BRD-K11566857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37763
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.36583
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.38488
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36588
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35755
AML193	CCLE Cell Line Gene Expression Profiles	1.0	1.4928
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.5671
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.017
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
YY1-21170310-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K47980183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29001
Temple syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.723
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.309
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904398
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_1_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPK-1526-SM-3MJGM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63204
18425577-TableS3a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883983
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05868
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.366558
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13737
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32178
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K14417813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00229
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.900685
BRD-A35495382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47158
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68897
BRD-K48459037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00101
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Supramolecular fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06142
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72438
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13675
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A0-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-0826-SM-447B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87584
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873331
NatB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.194
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15316
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68459
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04119
NCIH716	CCLE Cell Line Gene CNV Profiles	1.0	1.44561
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMS12BM	CCLE Cell Line Gene Expression Profiles	1.0	1.39498
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5228
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953957
histone acetyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K29366596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74361
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26708
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25961
testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K37912617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20443
Parabrachial nucleus, lateral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24137
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221827
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-80-XK94_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286332
BECKER	CCLE Cell Line Gene CNV Profiles	1.0	1.39792
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06834
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7471
LMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57634
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6013-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59088
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14405
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6945-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36084688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06229
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4476	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945683
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67706
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-2.10016
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K09378334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13062
CA-42-YI34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214845
GM2493	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.06091
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43X-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCCPAN2	CCLE Cell Line Gene Expression Profiles	1.0	1.75348
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994084
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23351
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92229
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35925
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.946032
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00744
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911948
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C1-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K75775113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27854
Gastric	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.56019
TCF3	ChEA Transcription Factor Targets	1.0	null
diclofenamide-5286	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
diversity	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45495792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03269
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292404
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846883
Inflammation	CTD Gene-Disease Associations	1.0	1.37418
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05888
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14951
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16912
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K51760683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2232
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975283
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.20751
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40252
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976407
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXO3	ChEA Transcription Factor Targets	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52691
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Chlorhexidine (diacetate)_AN3 CA	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0232041
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04423
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071606
BRD-K44935022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41214
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K96249452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10116
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.71201
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53885
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8633_SYS1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.540701
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06666
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21669
BRD-K17753765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47157
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23461342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31795
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF664	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34592
Anteromedial nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67354
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.934573
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28461
DD-74-PJ26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31251
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5234
BRD-K50423606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81442
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31654
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37864
Perturb_9855_KD_MSI2_SRP096137	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.29456
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.99632
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75618633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4508
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959231
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16972
NCIH520	DepMap CRISPR Gene Dependency	1.0	2.72948
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77603
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841431
Ubiquitin activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.71
hsa-miR-4722-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PR, GR	MotifMap Predicted Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880347
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.999037
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04929
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HAP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
OC314	DepMap CRISPR Gene Dependency	1.0	4.73282
GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K31081052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49803
Chloroplast ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895694
BRD-K68347834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12846
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9686_UTP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.618825
1349_CCT5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.639355
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.329
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83446
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
E2F6	ENCODE Transcription Factor Targets	1.0	null
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-24-ZNF587_ZNF587	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48338
NSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.535
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASPC1	CCLE Cell Line Gene Expression Profiles	1.0	1.77798
chromatin organization	GO Biological Process Annotations 2023	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268062
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.0208
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.893972
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11871
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853156
hsa-miR-4731-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
hsa-miR-1207-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
BRD-K87742870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73362
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
chromatin organization	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4692	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890786
GTEx Skin 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-9.65071
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.43402
nucleosome organization	GO Biological Process Annotations 2023	1.0	null
tibia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.896045
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
1941_CTPS1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.70736
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12995
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853118
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21735
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.643
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61735
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36544
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00578
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17044
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10424
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5708
8855_TFPT_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.67378
BRD-K74817844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69721
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07483
BRD-K60760423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4277
Neurogenic Muscular Atrophy_Muscle - Striated (Skeletal) (MMHCC)_GSE2566	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.14397
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE258991_5_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K78623319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42951
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.124651
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
PMC12913833-12672_2026_4481_MOESM3_ESM.xlsx-Table_S1-Table_S1_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.99
GTEX-XUZC-0726-SM-4BOPH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.84875
TC138	DepMap CRISPR Gene Dependency	1.0	2.62616
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.955334
BRD-K61315077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7816
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90103010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13828
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980135
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10997
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29638
BRD-K55478267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91413
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3652	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
BRD-K95160020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21587
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32673
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.903175
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.55194
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.8502
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52288
nod2_21335489_hek293_lof_human_gpl570_gds4416	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.07025
BRD-K16190564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22795
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.824536
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood pressure	GAD Gene-Disease Associations	1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15737
BRD-K72060858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98348
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211675
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.638974
BRD-K11282060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05796
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.246
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00924
Lung squamous cell carcinoma_LUSC_TCGA-94-A4VJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
3637_HAUS4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.58026
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8753
Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05506
BRD-K95768123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25786
BRD-A86550573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75073
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
DE-30-UR76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286905
BRD-K34445094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36137
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36554
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.22021
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
external cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26545
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01402
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34315
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K35646839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0449
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52175660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4722
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IC-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92477
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6101
peptidyl-methionine modification	GO Biological Process Annotations 2025	1.0	null
GSE153189_1_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
peptide alpha-n-acetyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26043
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE104508_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
recurrent infections	GWASdb SNP-Phenotype Associations	1.0	0.33503
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18111
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03126
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55813
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43327
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50851
BRD-K27864398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18479
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.89814
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2819
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843273
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36831
Acute Myeloid Leukemia_LAML_TCGA-AB-2932-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9691391-7945884.f3.pdf-196-ENSG00000213988_ZNF90	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null