association dataset threshold value standardized value H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SARS-BatSRBD_Day2_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.97409 BRD-K42663584 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83711 BRD-K36644177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37241 transferase activity, transferring acyl groups other than amino-acyl groups GO Molecular Function Annotations 2015 1.0 null dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.03659 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.13056 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.953199 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08531 BRD-K21409337 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47143 GATA3_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null LK2 Achilles Cell Line Gene Essentiality Profiles 1.0 1.30122 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29094 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923052 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.961984 BRD-K71253424 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6512 BRD-K61386375 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35503 superficial stratum of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46246 homo GeneRIF Biological Term Annotations 1.0 null KMH2 CCLE Cell Line Gene CNV Profiles 1.0 1.66833 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41036 H3K27me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus of the inferior collicular brachium, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.59108 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-01A-02R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.884949 Lung adenocarcinoma_LUAD_TCGA-50-5930-11A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K56253099 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67798 peptide metabolic process GO Biological Process Annotations 2015 1.0 null SF3B1 Pathway Commons Protein-Protein Interactions 1.0 null Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZM-01A-12R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYBL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18531 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.02287 Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77186 NR2F2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neurological pain disorder_Dorsal Root Ganglia_GSE15041 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.49784 superficial stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07555 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-XS-A8TJ-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K77953978 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.98041 BRD-K41798816 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46579 MYBL2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLM6 CCLE Cell Line Gene Expression Profiles -1.0 -2.68842 NCIH1623 CCLE Cell Line Gene CNV Profiles 1.0 1.82782 Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein modification process GO Biological Process Annotations 2015 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular metabolic process GO Biological Process Annotations 2015 1.0 null OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11437 superior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33945 ChIP_SETDB1_19884257 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null OCIM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.94276 negative regulation of programmed cell death GO Biological Process Annotations 2023 1.0 null mRNA_NANOG_16518401 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36787 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.02287 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58119 BRD-K31093279 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12559 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31743 BRD-K65932559 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.94289 BRD-K14098658 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1293 Lung squamous cell carcinoma_LUSC_TCGA-56-A5DS-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF12_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37222 primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.7737 BRD-K10105458 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11691 BRD-K90151990 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48303 BRD-K89770910 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12805 BRD-K98239824 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43154 UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29555 Infralimbic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25979 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5916 CAL-39 GDSC Cell Line Gene Expression Profiles 1.0 1.79955 BRD-K87658102 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53302 BRD-K60456515 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.72815 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VK-01A-21R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retrosplenial area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21214 BRD-K83670600 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.59539 ABC1 CCLE Cell Line Gene Expression Profiles -1.0 -1.82987 mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null right pulmonary isomerism MGI Mouse Phenotype Associations 2023 1.0 null HT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.58185 SETDB1 ChEA Transcription Factor Targets 1.0 null Wholebrain BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.35197 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.957473 external segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21096 PARP1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K30173809 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65734 CMK115 CCLE Cell Line Gene Expression Profiles 1.0 1.45273 septal nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.964142 r3 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21901 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar white matter Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26561 Immune System Diseases CTD Gene-Disease Associations 1.0 1.04126 isthmus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46376 hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.80289 ott1_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.543782 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SP1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A05823365 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.22307 REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hemispheric regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42507 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02381 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNRNPA1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K73899643 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36056 BRD-K47203692 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06435 superficial stratum of r4BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42231 H3K9me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNU324 CCLE Cell Line Gene CNV Profiles -1.0 -2.40944 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.862887 Hypercholesteremia_Hepatic Tissue_GSE3889 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -3.81957 intermediate stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14235 Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01991 Cell Transformation, Neoplastic CTD Gene-Disease Associations 1.0 1.05573 JUND ENCODE Transcription Factor Targets 1.0 null Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21269 BRD-K33005275 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22658 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null peptidyl-lysine modification GO Biological Process Annotations 2015 1.0 null layer 1 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19257 SRY ChEA Transcription Factor Targets 1.0 null SCABER CCLE Cell Line Gene Expression Profiles -1.0 -1.87013 SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QK-01B-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEAD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K97486995 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23997 mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.980849 hsa-miR-363 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 KPNYN CCLE Cell Line Gene CNV Profiles 1.0 1.61869 NONO Pathway Commons Protein-Protein Interactions 1.0 null internal granular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48264 peptidyl-lysine N6-acetylation GO Biological Process Annotations 2023 1.0 null membrane part GO Cellular Component Annotations 2015 1.0 null reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.983708 BRD-K80073743 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47956 primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12937 BRD-K31479652 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17151 H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CL34 CCLE Cell Line Gene Expression Profiles 1.0 2.79188 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5174-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F2 ENCODE Transcription Factor Targets 1.0 null superficial stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14874 Lobule III, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.6324 EBC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.46594 endoplasmic reticulum membrane GO Cellular Component Annotations 2023 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11492 REST_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02497 BRD-K49584663 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.322 N-acyltransferase activity GO Molecular Function Annotations 2023 1.0 null Magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40368 BRD-K84707727 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02282 BRD-K76342376 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23913 ventral entopeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21901 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.62871 dextrocardia MGI Mouse Phenotype Associations 2023 1.0 null internal peptidyl-lysine acetylation GO Biological Process Annotations 2015 1.0 null BRD-K10798676 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.23369 atase2 GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76O-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null vomeralnasalorgan.VMO. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.828725 Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25835 BRD-K49945344 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26829 BRD-K73730918 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44713 mRNA_NR2F2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BRD-K81501934 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68428 RCOR1 ENCODE Transcription Factor Targets 1.0 null BRD-K53326976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07021 BRD-K15273135 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52313 FU97 CCLE Cell Line Gene Expression Profiles 1.0 1.67631 NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.83701 NCIH2171 CCLE Cell Line Gene Expression Profiles -1.0 -2.3671 Lobule III Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.53173 BRD-K55763052 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05602 NCIH508 CCLE Cell Line Gene Expression Profiles 1.0 1.97012 BRD-A20314546 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08252 DETROIT562 CCLE Cell Line Gene CNV Profiles -1.0 -1.39551 HT29 BioGPS Cell Line Gene Expression Profiles 1.0 2.09358 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.888211 POLR2A_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K23280067 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07422 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46275 r4 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25454 TCF12 ENCODE Transcription Factor Targets 1.0 null BRD-K74176533 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38962 Adrenocortical carcinoma_ACC_TCGA-OR-A5LG-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC-18940864-HL60-human ChEA Transcription Factor Binding Site Profiles 1.0 null gigantocellular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.95282 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.62705 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.937065 BRD-K26200435 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21949 BRD-K63547380 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.80769 FOSL2 ENCODE Transcription Factor Targets 1.0 null WholeBlood BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.0489 BRD-K23440419 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03311 HNF4A-19761587-HUMAN INTESTINAL CELL LINE CACO-2-human ChEA Transcription Factor Binding Site Profiles 1.0 null midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.19203 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.941324 BRD-K61315077 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42646 LCLC-97TM1 GDSC Cell Line Gene Expression Profiles -1.0 -1.44697 BRD-K61039403 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.88467 Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K29903367 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03639 cerebellum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16971 Kidney renal papillary cell carcinoma_KIRP_TCGA-PJ-A5Z9-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rhombomere 11 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66264 MAFF ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HI-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2998 BioGPS Cell Line Gene Expression Profiles -1.0 -1.44483 Dopaminergic A13 group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09058 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80319 VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.886841 REST_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null atrioventricular septal defect MGI Mouse Phenotype Associations 2023 1.0 null A-VN-1203-2004(H5N1)_Day1-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.59839 amyloid fibril formation GO Biological Process Annotations 2023 1.0 null inhibition GeneRIF Biological Term Annotations 1.0 null Lobules IV-V, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.27225 Depressive Disorder CTD Gene-Disease Associations 1.0 1.09471 superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05448 layer 4 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12422 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55291 H3K4me1_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57966 DDX17 Pathway Commons Protein-Protein Interactions 1.0 null Reflex, Abnormal CTD Gene-Disease Associations 1.0 1.21402 BRD-K47366416 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.78166 endoplasmic reticulum-golgi intermediate compartment membrane GO Cellular Component Annotations 2015 1.0 null Liver Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.492 form GeneRIF Biological Term Annotations 1.0 null H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HNF4A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null gastrulation GO Biological Process Annotations 2023 1.0 null MAP3K1_knockout_245_GSE39240 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.38527 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH23 CCLE Cell Line Gene CNV Profiles 1.0 1.362 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.826102 BRD-K71486446 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47483 r3 part of parvicellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01537 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1254 BRD-K60337516 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.84391 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19W-06A-41R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Fetallung BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.86124 BRD-K75252192 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16123 BRD-K47801291 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05299 G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.966164 BRD-A71666580 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75708 BRD-K05939258 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02916 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A0-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uvula (IX) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23798 subbrachial nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16522 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.22512 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37381 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67835 BRD-K60069390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26924 Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55938 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01709 NCIH441 Achilles Cell Line Gene Essentiality Profiles -1.0 -2.13589 intracellular organelle GO Cellular Component Annotations 2015 1.0 null ERBB2_knockdown_234_GSE8373 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.86366 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of nucleus gracilis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14522 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K63401195 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.8998 mantle zone of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35915 REST_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KSR2_knockout_60_GSE17923 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.01401 intermediate isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28077 Precancerous Conditions CTD Gene-Disease Associations 1.0 1.59873 mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null BRD-K88070218 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17812 HDAC2 ENCODE Transcription Factor Targets 1.0 null anterior pretectal nucleus, ventral superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01023 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-423 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923052 Lung adenocarcinoma_LUAD_TCGA-44-6145-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Essential Thrombocytemia_Thrombocyte_GSE2006 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.67504 increased heart ventricle size MGI Mouse Phenotype Associations 2023 1.0 null BRD-K63859730 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09341 GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAB3A_Mutation - D77G point mutation_GDS2483_698_mouse_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K31783598 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.29098 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04985 primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.88397 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r10 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29313 Non-alcoholic Fatty Liver Disease CTD Gene-Disease Associations 1.0 1.31178 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superior parietal lobule, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.942723 mRNA_CBX8_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TM31 CCLE Cell Line Gene Expression Profiles -1.0 -1.46007 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59213 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02497 F36P Achilles Cell Line Gene Essentiality Profiles -1.0 -2.07727 shell of SCH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.106 BRD-K79561909 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79866 BRD-K98889734 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09087 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CL11 CCLE Cell Line Gene Expression Profiles -1.0 -1.61669 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null sodium-phenylacetate LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36993 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K27172015 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.99063 NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923052 NIHOVCAR3 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.06277 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-MQ-A6BL-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K20284960 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11187 BRD-A61767497 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08048 BRD-K70584304 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49845 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7J2-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28077 smallintestine BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 TAL1 ENCODE Transcription Factor Targets 1.0 null n-acyltransferase activity GO Molecular Function Annotations 2015 1.0 null KYSE450 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 Orbital area, ventrolateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02937 BRD-K85722200 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36163 BRD-K86373784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52845 superior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07408 BRD-A20182314 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13063 REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61711 BRD-K95575699 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04932 outer SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46929 H3K36me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K31660953 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00668 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03889 BRD-K88925664 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06601 PECAPJ49 CCLE Cell Line Gene CNV Profiles -1.0 -2.16037 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K00323141 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16654 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.10519 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53218 BRD-K73808079 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.37595 BRD-K14163107 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50429 BRD-K08219814 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.97661 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.56045 mRNA_NANOG_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.50413 cellular process GO Biological Process Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A50Z-01A-21R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A4-Fuk GDSC Cell Line Gene Expression Profiles 1.0 2.3212 RXRA_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K08730943 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.96773 amygdaloid complex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.827133 temporal muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30931 H1FX Pathway Commons Protein-Protein Interactions 1.0 null myb_16205643_primary_monocytes_gof_human_gpl570_gse2816 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.476468 BRD-A61778798 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4093 22RV1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.0213 RB1_KD_GSE50532_623_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.985818 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J8-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hydrops fetalis MGI Mouse Phenotype Associations 2023 1.0 null BRD-K39546571 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.12793 Primary somatosensory area, trunk, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00028 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lobule II Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73094 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K75260889 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.89544 SNU503 CCLE Cell Line Gene CNV Profiles 1.0 2.59938 dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.913417 CHD1 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K09378334 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20474 A-VN-1203-2004(H5N1)_Day4-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.37305 Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEK 293 T-rex BioGPS Cell Line Gene Expression Profiles 1.0 1.37108 IZ in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.861396 Lung squamous cell carcinoma_LUSC_TCGA-60-2724-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K69350885 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83036 BRD-K09108485 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.00088 kidney BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 Infralimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24788 SP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.941409 caudal group of intralaminar nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.841339 Superior olivary complex, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04962 FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null gastrulation with mouth forming second GO Biological Process Annotations 2015 1.0 null hydrocortisone_homo sapiens_gpl201_gse21909 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K92749855 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32613 16651409-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K55939029 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60976 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLR26 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.09276 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1173 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K31300534 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02281 RXRA_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hMPV_24Hour_18234263_GSE8961 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.19157 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R2-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bace1 GeneRIF Biological Term Annotations 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null heterodimers GeneRIF Biological Term Annotations 1.0 null BRD-K75164441 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57452 GP2D CCLE Cell Line Gene Expression Profiles 1.0 1.43348 outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22899 BRD-K73357010 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77143 laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01557 NH6 CCLE Cell Line Gene Expression Profiles -1.0 -1.67847 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10201 r6 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75473 endoplasmic reticulum part GO Cellular Component Annotations 2015 1.0 null superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.12648 posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.902028 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.926803 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.30274 Lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06579 BRD-A05456882 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.417 BRD-K62758843 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83102 BRD-K06678077 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48235 ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.39174 macromolecule modification GO Biological Process Annotations 2015 1.0 null EGR1 ChEA Transcription Factor Targets 1.0 null BRD-K36320220 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.2364 Uterus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.939046 REST_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12118 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.95366 RBBP5 ENCODE Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A815-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsomedial preoptic area, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06862 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32205 BRD-K22725588 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84664 BRD-K95435237 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38757 BRD-K82930531 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06766 RXRA ENCODE Transcription Factor Targets 1.0 null BRD-K36923996 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.397 Acyl-CoA N-acyltransferase InterPro Predicted Protein Domain Annotations 1.0 null HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02497 SK-MES-1 GDSC Cell Line Gene Expression Profiles 1.0 2.49481 PC-3 GDSC Cell Line Gene Expression Profiles -1.0 -1.4934 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor GO Molecular Function Annotations 2023 1.0 null CMK CCLE Cell Line Gene Expression Profiles 1.0 1.62178 generation GeneRIF Biological Term Annotations 1.0 null BRD-K57650037 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16859 BRD-A80705936 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57462 Primary motor area, Layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11796 Orbital area, ventrolateral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16068 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.769189 BRD-K95543908 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34632 superficial stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36787 tcof1_15522210_neuroblastoma_lof_mouse_gpl339_gds998 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.073659 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05397 Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K11404512 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30947 BRD-K96218803 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52055 H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K33221810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16631 BRD-A74615450 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42211 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67835 dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10356 Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.39928 regulation of metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K80546581 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37328 NCIH2171 Achilles Cell Line Gene Essentiality Profiles 1.0 1.04479 SARS-CoV_48Hour_20090954_GSE17400 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.54467 posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.895086 HARA CCLE Cell Line Gene CNV Profiles -1.0 -1.41199 sirolimus_homo sapiens_gpl2895_gse16944 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K37760996 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00804 BRD-K29328556 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83825 17975224-TableS6 GeneSigDB Published Gene Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NP-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rbm15_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.543782 POR_KO_GDS1678_763_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K59772014 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42057 Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OH-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K85633971 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03214 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.78072 MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null cyclothiazide LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11788 regulation of gene expression GO Biological Process Annotations 2023 1.0 null midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.945835 BRD-K79709959 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10508 BRD-K15128331 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05398 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28091 central layers of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39058 BRD-K66708851 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.10084 Subceruleus nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.99074 Lassa Fever Virus_24hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.84943 hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50081 A704 CCLE Cell Line Gene Expression Profiles -1.0 -2.12864 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.53426 BRD-A04618830 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16401 isthmic alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54165 H4 GDSC Cell Line Gene Expression Profiles 1.0 1.77048 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.75915 Arteriosclerosis CTD Gene-Disease Associations 1.0 1.03678 primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.84056 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C9-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BRD-K99525048 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08268 mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19835 liminal part of r4 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15849 BRD-K82784817 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57448 HLFA CCLE Cell Line Gene Expression Profiles -1.0 -2.12413 molecular_function GO Molecular Function Annotations 2015 1.0 null Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.38079 Inflammation CTD Gene-Disease Associations 1.0 1.7424 DMNB LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.97494 cellular_component GO Cellular Component Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUGC-3 GDSC Cell Line Gene Expression Profiles -1.0 -1.45781 BRD-K89040444 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42985 intermediate stratum of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3461 BRD-K44779507 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52339 cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64538 ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.022618 RS11846 BioGPS Cell Line Gene Expression Profiles 1.0 1.08506 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0963 SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.001 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4640-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K83189379 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67843 BRD-K63462027 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02153 ventral isthmic part of dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1016 BRD-K41719231 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1272 acetyltransferases GeneRIF Biological Term Annotations 1.0 null intermediate stratum of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35464 organelle part GO Cellular Component Annotations 2015 1.0 null BRD-K78202004 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03608 REST_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K67353973 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.69029 BRD-K76515685 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.24202 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null BRD-K87647164 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01638 bounding membrane of organelle GO Cellular Component Annotations 2015 1.0 null REST_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K17245631 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08198 preoptic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24736 LHX1_NULL MUTATION - Ablation_GDS1748_749_mouse_Embryonic kidneys (from day E18.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.940074 BRD-K04875192 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18703 Uvula (IX), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23144 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29008 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06705 BRD-K39649723 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63865 BRD-K87821938 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54811 HNRNPK Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A6I9-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.66171 heterotaxia MGI Mouse Phenotype Associations 2023 1.0 null MV411 CCLE Cell Line Gene Expression Profiles -1.0 -1.59263 A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_1day-MOI-10^4_None_GSE37572 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.52833 HCC1599 CCLE Cell Line Gene CNV Profiles 1.0 1.49208 CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_766_mouse_Skin - 0 Day GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null OVCAR4 Achilles Cell Line Gene Essentiality Profiles -1.0 -2.06738 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A72E-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE5 CCLE Cell Line Gene Expression Profiles -1.0 -1.49312 H3K9me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8154-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null muscular ventricular septal defect MGI Mouse Phenotype Associations 2023 1.0 null RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.59261 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00533 TOP2A Pathway Commons Protein-Protein Interactions 1.0 null pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12118 p1 part of the substantia nigra compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06578 BRD-K53643174 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39492 REST_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02381 SNU899 CCLE Cell Line Gene CNV Profiles 1.0 1.82271 Uvula (IX), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24695 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A719-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null internal peptidyl-lysine acetylation GO Biological Process Annotations 2023 1.0 null LN319 Achilles Cell Line Gene Essentiality Profiles 1.0 1.67218 Rectum adenocarcinoma_READ_TCGA-AF-5654-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.910429 BRD-K99404845 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37392 OVCAR3 BioGPS Cell Line Gene Expression Profiles 1.0 0.888521 V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3689 principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.80478 H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01999 Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5427 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17153 mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12075 mantle zone of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04166 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7594-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K48756106 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.24516 BRD-K92378241 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.37632 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.48644 superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21565 FOXA1_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKMM2 Achilles Cell Line Gene Essentiality Profiles 1.0 1.02407 BRD-K28983467 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30021 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AW-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K64509887 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10509 BRD-K05841284 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79271 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K71109636 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1986 Declive (VI), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.60211 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36642 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53218 BRD-K92524823 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.34957 r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19835 posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13042 REST_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of apoptotic process GO Biological Process Annotations 2023 1.0 null HNRNPA3 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-93-A4JP-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2196 CCLE Cell Line Gene CNV Profiles -1.0 -2.01718 KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46499 reticulumbased GeneRIF Biological Term Annotations 1.0 null SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16428 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K06719105 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37217 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29435 G-402 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71304 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907864 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.903021 Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16568 core part of DTg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23481 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6790-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K39824708 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.76108 hsa-miR-32 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHH5 CCLE Cell Line Gene Expression Profiles 1.0 2.05268 Liver hepatocellular carcinoma_LIHC_TCGA-LG-A6GG-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K19009697 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33451 T47D CCLE Cell Line Gene CNV Profiles -1.0 -1.34821 MYBL2 ENCODE Transcription Factor Targets 1.0 null BRD-K47887272 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12769 Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perireunensis nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08503 BRD-K58323923 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23703 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BY-01A-31R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K69668687 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04945 REST_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3705 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21124 BRD-A05422420 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71231 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.944428 BRD-K81543095 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45167 Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endoplasmic reticulum-Golgi intermediate compartment membrane GO Cellular Component Annotations 2023 1.0 null H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K98225007 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52785 Anxiety Disorders CTD Gene-Disease Associations 1.0 1.06044 BRD-K16279128 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35458 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23746 protein acylation GO Biological Process Annotations 2015 1.0 null U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10201 Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31095 tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38607 TF1 CCLE Cell Line Gene Expression Profiles 1.0 1.52816 regulation of biological process GO Biological Process Annotations 2015 1.0 null superficial stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68899 inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.945871 n-acetyltransferase activity GO Molecular Function Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TA-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA1_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2406 GM2493 BioGPS Cell Line Gene Expression Profiles 1.0 1.12642 BRD-K10398797 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.95259 rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null REST_Panc1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K60898929 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68816 BRD-K39435284 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15107 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00533 BRD-K85664064 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27547 KO52 CCLE Cell Line Gene Expression Profiles 1.0 1.44676 beta-amyloid metabolic process GO Biological Process Annotations 2015 1.0 null BE-13 GDSC Cell Line Gene Expression Profiles 1.0 1.47123 peptide metabolic process GO Biological Process Annotations 2023 1.0 null Disease Models, Animal CTD Gene-Disease Associations 1.0 1.16035 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.7848 BRD-K82814367 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09542 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IE-01A-21R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K32176914 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.1263 USF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MedullaOblongata BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.25609 JHH1 CCLE Cell Line Gene Expression Profiles -1.0 -2.3446 SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923052 BRD-K00882360 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13097 MET_knockout_253_GSE30651 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.51055 SFPQ Pathway Commons Protein-Protein Interactions 1.0 null Adenoma, Liver Cell CTD Gene-Disease Associations 1.0 1.13621 H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K34447537 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.8235 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08453 BRD-K86911380 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72548 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.99125 BRD-K78960724 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04055 UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.05215 regulation of cellular process GO Biological Process Annotations 2015 1.0 null LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TE4 CCLE Cell Line Gene CNV Profiles 1.0 1.42873 Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPARA_Deficiency_GDS2934_632_mouse_Small intestine GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K23366960 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10965 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null gyrus rectus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04568 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.884028 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4347-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K85359206 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59147 REST_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31743 ESR1_T47D_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUZ12_DEPLETION_GDS2445_119_human_embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-A52749901 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33777 H3K4me1_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08531 endoplasmic GeneRIF Biological Term Annotations 1.0 null deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29634 tectal gray formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78963 TE11 CCLE Cell Line Gene CNV Profiles -1.0 -1.37198 HCV_8week-No IFN-a_None_GSE37715 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.69238 BRD-K01121723 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.05439 BRD-K78347804 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30569 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.887102 TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -1.56683 hsa-miR-3974 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 BRD-K29702569 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79237 SRSF1 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.106 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K18296568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.60782 horizontal nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88846 inferior frontal gyrus, opercular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38479 Cerebellar cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61314 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QF-01A-21R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral division of VL Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.98584 mRNA_SFPI1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.961793 MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08531 BRD-K01286616 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12832 LAMA84 CCLE Cell Line Gene CNV Profiles -1.0 -1.68443 H3K27ac_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923052 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17336 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEC251 CCLE Cell Line Gene CNV Profiles 1.0 1.37526 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.955234 MYC ChEA Transcription Factor Targets 1.0 null BRD-K48860650 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23733 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06165 endoplasmic reticulum-golgi intermediate compartment GO Cellular Component Annotations 2015 1.0 null BRD-K40558736 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09075 USF1 ENCODE Transcription Factor Targets 1.0 null fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.857645 single-organism developmental process GO Biological Process Annotations 2015 1.0 null enlarged lymph nodes MGI Mouse Phenotype Associations 2023 1.0 null HNF4A ENCODE Transcription Factor Targets 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21965 r2 part of superior vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56207 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76911 BRD-K35209334 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.85528 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A2C5-01A-12R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.92121 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null right-sided stomach MGI Mouse Phenotype Associations 2023 1.0 null BRD-K76654183 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61349 Fatty Liver CTD Gene-Disease Associations 1.0 1.77743 Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03129 H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12181 primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22415 supramolecular fiber organization GO Biological Process Annotations 2023 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-68-7757-01B-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67835 PANC-10-05 GDSC Cell Line Gene Expression Profiles -1.0 -2.23937 Dorsal peduncular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22109 nucleus of the inferior collicular brachium, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40858 BRD-K77820593 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52564 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.857655 REST_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K23241743 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6698 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null negative regulation of apoptotic process GO Biological Process Annotations 2023 1.0 null HEC265 CCLE Cell Line Gene CNV Profiles 1.0 1.81929 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.932129 BRD-K27616003 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.44037 BRD-K97624648 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21663 BHLHE40 ENCODE Transcription Factor Targets 1.0 null preoptic telencephalon Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27372 cellular protein modification process GO Biological Process Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5784-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A06471483 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32264 organelle GO Cellular Component Annotations 2015 1.0 null BRD-K19492738 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57199 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBL1XR1 ENCODE Transcription Factor Targets 1.0 null BRD-K47471281 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42225 BRD-K14533399 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.8051 dorsal subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18216 MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.862337 HT CCLE Cell Line Gene CNV Profiles -1.0 -3.20995 Lobules IV-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.23581 BRD-K09711841 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31578 BRD-K18031793 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0417 BRD-K37596331 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.11336 BRD-K75738997 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.66037 superficial stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75473 Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74883 BRD-K20435953 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.90318 COLO741 CCLE Cell Line Gene Expression Profiles -1.0 -1.93678 ATF1 ENCODE Transcription Factor Targets 1.0 null mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27372 BRD-K20073772 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6155 polymorph layer of TuStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6692 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A3X6-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null integral component of membrane GO Cellular Component Annotations 2015 1.0 null primary auditory cortex (core)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02231 Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RH30 CCLE Cell Line Gene CNV Profiles 1.0 2.22168 BRD-K96284156 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24239 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K86036680 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22513 BRD-K51844455 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35685 organonitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null r4 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35029 BRD-K25045770 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09426 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BK-01B-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retrosplenial area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26974 BRD-K86774687 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.20761 BRD-K88645787 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06898 BRD-K91973560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.02231 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.201 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K33998683 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.92912 TRIM28_knockout_301_GSE32224 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.22393 cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61114 mantle zone of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39121 hsa-miR-92a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 HNRNPR Pathway Commons Protein-Protein Interactions 1.0 null BRD-K94306568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31103 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23991 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A9-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K47883435 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00237 RKN Achilles Cell Line Gene Essentiality Profiles 1.0 1.49227 Dystocia CTD Gene-Disease Associations 1.0 1.11775 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01999 BRD-K59064238 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40085 BRD-K72936860 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32645 BRD-K08881846 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.50158 Copula pyramidis, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01339 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-719 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00533 hsa-miR-367 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 BRD-K67458784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45707 HEL9217 CCLE Cell Line Gene Expression Profiles 1.0 1.86978 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Orbital area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22805 Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KURAMOCHI CCLE Cell Line Gene CNV Profiles 1.0 1.79114 SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Lobule II, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84468 wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.037376 hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.829426 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SG-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K12683022 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.3242 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r2 part of nucleus subcoeruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22247 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K92644013 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43593 Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5907-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26C-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K99131664 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03794 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15602 HEL CCLE Cell Line Gene Expression Profiles 1.0 1.42255 NCI-H2347 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.888211 A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.61822 BRD-K44856541 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34691 negative regulation of cellular process GO Biological Process Annotations 2015 1.0 null LN18 BioGPS Cell Line Gene Expression Profiles -1.0 -0.856461 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.892305 BRD-A81407814 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.0464 intermediate stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29313 hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00505 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.940074 BRD-K26195700 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10271 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Medullary reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01286 BRD-K90092568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.63901 BRD-K74632893 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1216 TK10 GDSC Cell Line Gene Expression Profiles 1.0 1.6552 ESR1 JASPAR Predicted Transcription Factor Targets 1.0 null polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.858755 U20S BioGPS Cell Line Gene Expression Profiles -1.0 -0.937 hsa-miR-4320 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 NOMO1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.85763 NCIH1650 CCLE Cell Line Gene CNV Profiles 1.0 1.51256 cytoplasmic part GO Cellular Component Annotations 2015 1.0 null LB647-SCLC GDSC Cell Line Gene Expression Profiles 1.0 1.44977 Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K89447678 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40876 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4154-01A-01R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K31372389 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71827 BRD-K82194980 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22326 BRD-K06816455 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28622 BRD-K06698399 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05624 H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.58185 Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58523 Heart Diseases CTD Gene-Disease Associations 1.0 1.08337 increased fasting circulating glucose level MGI Mouse Phenotype Associations 2023 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K31336762 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13183 BRD-K44309337 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02578 JUND_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null transverse gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.896936 BRD-A55722685 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17441 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV2-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24749 Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K31820800 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6593 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03639 Lung squamous cell carcinoma_LUSC_TCGA-22-1011-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null positive regulation of macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K92513859 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4528 baclofen_mus musculus_gpl1261_gse17266 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null transferase activity, transferring acyl groups GO Molecular Function Annotations 2015 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU719 CCLE Cell Line Gene CNV Profiles 1.0 1.34477 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.73928 SG in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 BRD-A47798787 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.52212 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.830066 CTCF ENCODE Transcription Factor Targets 1.0 null Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16949 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K46805838 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03273 H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38005 superficial stratum of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21901 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K95839423 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15774 periventricular mantle of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1005 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.941324 Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33187 layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0277 BRD-K37515001 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.60007 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.8816 cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K77119472 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10398 A-Vietnam-1203-2004(H5N1)_2day-TNFRSF1BKO_None_GSE40792 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.61896 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null betasecretase GeneRIF Biological Term Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K44705560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22242 NU-1025-313 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-A63342325 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.17358 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32089 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14161 Lung adenocarcinoma_LUAD_TCGA-44-6146-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEAD4_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62865 C2BBe1 GDSC Cell Line Gene Expression Profiles 1.0 1.92057 TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lobule II, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67556 BRD-K20897375 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07658 BRD-K54456668 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07383 BRD-K60166659 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3089 GATA3 ENCODE Transcription Factor Targets 1.0 null Blood Coagulation Disorders CTD Gene-Disease Associations 1.0 1.02896 AICD_Induced expression / Over-expression_GDS1979_288_human_SHEP-SF neuroblastoma GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SKMEL3 CCLE Cell Line Gene Expression Profiles -1.0 -1.58823 UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K15460257 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20963 GATA3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42C-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral part of r3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35464 BRD-K62150807 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00021 SW1271 CCLE Cell Line Gene Expression Profiles -1.0 -1.57838 BRD-A78982410 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.44926 SP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01601 KO52 CCLE Cell Line Gene CNV Profiles 1.0 1.64243 SNU869 CCLE Cell Line Gene CNV Profiles -1.0 -2.07027 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44926 BRD-A47615980 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14998 NR2F2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K93956318 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45013 BRD-K19946529 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.02009 first (dorsal) preoptic domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26198 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.29625 basolateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18343 anatomical structure morphogenesis GO Biological Process Annotations 2015 1.0 null NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.901504 CMK86 CCLE Cell Line Gene Expression Profiles 1.0 1.40081 BRD-K10211218 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.22592 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.21966 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847953 BRD-K50129495 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07155 BRD-K14258088 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54481 BRD-K83832060 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0351 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.926803 isthmic roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42993 Brain Lower Grade Glioma_LGG_TCGA-FG-A711-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.93626 BRD-K94692455 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.85183 HIV - Human immunodeficiency virus infection_T lymphocyte_GSE2504 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.22102 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null coronary fistula MGI Mouse Phenotype Associations 2023 1.0 null H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.3123 JHOC5 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.0661 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.94654 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08214 developmental process GO Biological Process Annotations 2015 1.0 null BRD-K17790291 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19954 primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14939 anteroventral periventricular preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33365 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10201 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.888703 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5U8-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K80225716 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06767 BRD-K98156994 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06031 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3362-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K78866630 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05922 r1 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3372 CALU1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.7088 HIST1H1C Pathway Commons Protein-Protein Interactions 1.0 null GATA3_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7873-01B-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null positive regulation of macromolecule metabolic process GO Biological Process Annotations 2023 1.0 null OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.953067 Metapathway biotransformation(Homo sapiens) WikiPathways Pathways 2014 1.0 null REST_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15522 H3K9me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K52218664 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19308 BRD-K30963311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17352 HNRNPC Pathway Commons Protein-Protein Interactions 1.0 null oligosaccharyltransferase GeneRIF Biological Term Annotations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taenia tecta, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00534 Dorsal tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22337 BRD-K32893898 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63678 BRD-K80880605 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81605 lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34877 periventricular stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26579 BRD-K48533326 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20472 superficial stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78523 BRD-K73427605 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.81342 peptidyl-amino acid modification GO Biological Process Annotations 2015 1.0 null BRD-K34004579 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1418 positive regulation of metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K73176613 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.90004 BRD-K81200901 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.99971 mantle zone of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5343 mantle zone of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7823 NCIH2141 CCLE Cell Line Gene CNV Profiles -1.0 -1.77238 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RKO Achilles Cell Line Gene Essentiality Profiles -1.0 -1.04414 SARS-CoV MA15_Day1-PFU-10^3_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.63926 molecular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45751 periventricular stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01286 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31743 BRD-K86893953 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12702 callosal sling Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.848613 MAX ENCODE Transcription Factor Targets 1.0 null BRD-K78162975 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11512 Purkinje cell layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41137 BRD-K08940439 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26233 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K12336887 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37493 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Y-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K08702524 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41962 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37769 RFX5 ENCODE Transcription Factor Targets 1.0 null mRNA_ATF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.39801 magnocellular superficial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36787 BRD-K32881384 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40691 BRD-A47416464 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36489 Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42691 Growth Disorders CTD Gene-Disease Associations 1.0 1.10734 bounding membrane of organelle GO Cellular Component Annotations 2023 1.0 null Lobules IV-V, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.20018 hsa-miR-4257 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 BRD-K43639523 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46476 BRD-K16266179 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2927 laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.82198 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17561 BRD-K00377328 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06743 BRD-K98505253 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.35607 prednisolone_mus musculus_gpl1261_gse21048 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null DDX5 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K15882320 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13861 NCIH1975 CCLE Cell Line Gene Expression Profiles -1.0 -2.52385 BRD-K98586629 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.205 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null protein acetylation GO Biological Process Annotations 2015 1.0 null BRD-K81099637 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29202 BRD-K04722226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54319 regulation of programmed cell death GO Biological Process Annotations 2015 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r4 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41308 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C8-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SHSYSY+RA BioGPS Cell Line Gene Expression Profiles -1.0 -1.25182 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Orbital area, ventrolateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07492 N-acetyltransferase activity GO Molecular Function Annotations 2023 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.852814 reduces GeneRIF Biological Term Annotations 1.0 null atase1 GeneRIF Biological Term Annotations 1.0 null double outlet right ventricle, ventricular defect committed to aorta MGI Mouse Phenotype Associations 2023 1.0 null c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.12037 Acute Myeloid Leukemia_LAML_TCGA-AB-2865-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r2 part of vestibular sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54001 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K83952475 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43509 Medullary reticular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33365 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Fetal Growth Retardation CTD Gene-Disease Associations 1.0 1.10246 Lymphnode BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.15857 diethylstilbestrol_mus musculus_gpl81_gse1839 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null protein metabolic process GO Biological Process Annotations 2015 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K89811208 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.62861 REST_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLM16 CCLE Cell Line Gene Expression Profiles 1.0 1.77601 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62618 BRD-K28919392 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46366 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.916869 Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62982 REST_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00215 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver Cirrhosis CTD Gene-Disease Associations 1.0 1.25525 BRD-K91467755 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34207 internal granular layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81264 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.86558 BRD-K04108962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.48074 NCI-H1623 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 17009876-tableS1b GeneSigDB Published Gene Signatures 1.0 null BRD-K66690073 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.05799 Atrophy CTD Gene-Disease Associations 1.0 1.52791 BRD-A52024592 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.93817 mRNA_MYC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null lateral preoptic nucleus, PO2 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13636 TEAD4 ENCODE Transcription Factor Targets 1.0 null anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05541 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846653 HCC1195 CCLE Cell Line Gene CNV Profiles 1.0 1.54214 hippocampus (hippocampal formation)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.93294 SW1463 CCLE Cell Line Gene Expression Profiles 1.0 1.84315 CEBPB_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null positive regulation of biological process GO Biological Process Annotations 2015 1.0 null Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.10424 BRD-K95479169 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10243 Vermal regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88876 BRD-K13267130 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2665 BRD-K33767223 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.9584 BRD-A55063801 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51271 MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hypertrophy CTD Gene-Disease Associations 1.0 1.87958 BRD-K59191599 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.09924 BRD-K74300740 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17327 BRD-K32988853 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.38256 KALS1 CCLE Cell Line Gene CNV Profiles -1.0 -1.52572 abeta GeneRIF Biological Term Annotations 1.0 null BRD-K51577639 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08068 hsa-miR-92b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 BRD-K29802952 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.54732 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.26578 SNU-C1 GDSC Cell Line Gene Expression Profiles 1.0 2.19359 Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K15433418 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32267 primary auditory cortex (core)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16224 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.827628 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.929263 U87MG Achilles Cell Line Gene Essentiality Profiles 1.0 1.1455 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null BRD-K29726765 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30745 BRD-K47200630 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41952 Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A06149038 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.84545 H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CREB1 JASPAR Predicted Transcription Factor Targets 1.0 null BRD-K40016301 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.69835 BRD-K20846358 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.65079 BRD-K57274378 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1148 BRD-K01734019 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04055 enlarged lymph nodes IMPC Knockout Mouse Phenotypes 1.0 null BRD-K89399989 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18356 CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0963 Lung squamous cell carcinoma_LUSC_TCGA-66-2771-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Simple lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60576 BRD-K12959846 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02617 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62618 YY1 ENCODE Transcription Factor Targets 1.0 null BRD-K64860451 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.86286 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55362 mRNA_SETDB1_19884255 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null BRD-K56179613 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31275 Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.06425 RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27107 BRD-K55814495 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00928 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6032-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K02118124 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11019 BRD-K55841827 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53467 rhombomere 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26561 hsa-miR-548v TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 mediodorsal nucleus of thalamus_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.958398 BRD-K76353834 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.27169 BFTC-909 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923052 BRD-K44864058 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21042 HCC70 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.05911 mesocardia MGI Mouse Phenotype Associations 2023 1.0 null REST_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81H-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K86838462 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54183 IM95 CCLE Cell Line Gene Expression Profiles 1.0 2.37573 BRD-K11275619 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.96015 r3 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35029 H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.98314 BRD-K14702616 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.98784 cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.50953 decamethonium LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19735 mRNA_ZFX_17448993 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BRD-K83553001 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52814 Kidney BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 REST_PFSK-1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null A172 BioGPS Cell Line Gene Expression Profiles -1.0 -1.15187 ZBTB7A ENCODE Transcription Factor Targets 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08722 U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42689 IRF1 ENCODE Transcription Factor Targets 1.0 null HEC59 CCLE Cell Line Gene CNV Profiles 1.0 2.18984 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30118 NAT10 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K77624847 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18516 BRD-K89632963 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63884 SP1 ENCODE Transcription Factor Targets 1.0 null NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923052 Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RL952 CCLE Cell Line Gene CNV Profiles 1.0 1.43517 SETDB1-19884257-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null POU5F1-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null double outlet right ventricle, Taussig bing type MGI Mouse Phenotype Associations 2023 1.0 null NCIH1395 CCLE Cell Line Gene CNV Profiles 1.0 1.38055 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.976525 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA3_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K00265832 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.55475 fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42324 BRD-K51163606 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4258 MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-7954-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-25 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 methylprednisolone_rattus norvegicus_gpl85_gds965 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null bed nucleus of the stria terminalis, laterocentral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00267 mRNA_SALL4_19060217 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5L4-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K34747076 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.87177 Anteroventral periventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04962 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.03079 EVSAT CCLE Cell Line Gene CNV Profiles -1.0 -1.56484 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.93774 molecular layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76302 HUH6 CCLE Cell Line Gene Expression Profiles 1.0 2.13085 NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44799 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4968-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW1573 CCLE Cell Line Gene CNV Profiles 1.0 1.34545 Lung adenocarcinoma_LUAD_TCGA-75-6205-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K24748087 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38381 FOXA1 ENCODE Transcription Factor Targets 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-ND-A4W6-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17191 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MG-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dorsal peduncular area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57836 HNF4A ChEA Transcription Factor Targets 1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.4192 Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null S-isopropylisothiourea LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5006 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4644-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84F-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K53319404 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.80088 intermediate stratum of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39058 PHF8 ENCODE Transcription Factor Targets 1.0 null BRD-K76114475 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.20511 BRD-K29086754 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5125 H3K27me3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K38345640 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19734 BRD-K09975370 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.06958 risedronate LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.672 BRD-K18000429 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.00276 BRD-K77403813 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48771 BRD-K92569554 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01711 BRD-K83673542 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3515 posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18385 BRD-K71514806 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30127 BRD-K69790201 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.05495 increased fasting circulating glucose level IMPC Knockout Mouse Phenotypes 1.0 null BRD-K96567801 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30139 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.910985 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K71647210 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23293 paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29206 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21562 protein binding GO Molecular Function Annotations 2015 1.0 null BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956371 mist1_22510200_pancreas_c57bl6_lof_mouse_gpl6246_gds4341 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 1.65064 BRD-K86155080 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.45551 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M8-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32045 regulation of macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null FBL Pathway Commons Protein-Protein Interactions 1.0 null BRD-K48221699 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19409 mantle zone of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25835 Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00635 BRD-K67399222 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16958 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.12271 cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39101 BRD-K09721123 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36468 647-V GDSC Cell Line Gene Expression Profiles -1.0 -1.67352 Lung adenocarcinoma_LUAD_TCGA-99-8028-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null negative regulation of programmed cell death GO Biological Process Annotations 2015 1.0 null Kidney Diseases CTD Gene-Disease Associations 1.0 1.50448 Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 2.02473 negative regulation of biological process GO Biological Process Annotations 2015 1.0 null BRD-K12239796 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3018 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of Pal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00315 BRD-K40220562 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.73346 anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66054 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SNUC1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.31768 r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21214 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inner SZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.917999 BRD-K86600397 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00079 REST_PFSK-1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null r2 part of the ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26974 posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19714 REST_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary metabolic process GO Biological Process Annotations 2015 1.0 null layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02458 catalytic activity GO Molecular Function Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null embryonic morphogenesis GO Biological Process Annotations 2015 1.0 null BRD-K18176829 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11838 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3450-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null QGP1 CCLE Cell Line Gene Expression Profiles -1.0 -1.47215 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07328 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 18614019-TableS4d GeneSigDB Published Gene Signatures 1.0 null prepontine hindbrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29467 REST_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Superior colliculus, motor related, intermediate gray layer, sublayer a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2404 MAZ ENCODE Transcription Factor Targets 1.0 null GOTO GDSC Cell Line Gene Expression Profiles -1.0 -1.9857 BRD-K83898111 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.70868 UT7 CCLE Cell Line Gene Expression Profiles 1.0 2.38277 BRD-K89760040 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39728 BRD-K23292451 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01817 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1 ENCODE Transcription Factor Targets 1.0 null frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25558 dorsolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24795 BRD-K03141963 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59995 Necrosis CTD Gene-Disease Associations 1.0 1.85221 Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08793 PDE10A_KO_GDS4542_292_mouse_hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null NCL Pathway Commons Protein-Protein Interactions 1.0 null Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12922 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29435 binding GO Molecular Function Annotations 2015 1.0 null oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.04978 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MI-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null short insular gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45983 Carcinoma, Hepatocellular CTD Gene-Disease Associations 1.0 1.53675 r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26582 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3444-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A64237946 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.32301 Cognition Disorders CTD Gene-Disease Associations 1.0 1.14747 BRD-K83254798 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28904 DMS454 CCLE Cell Line Gene CNV Profiles -1.0 -1.53174 Acute Myeloid Leukemia_LAML_TCGA-AB-2914-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ME1 CCLE Cell Line Gene Expression Profiles 1.0 1.70931 E2F6 ENCODE Transcription Factor Targets 1.0 null BRD-K16387460 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02042 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2227 Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14314 Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02087 acetyltransferase activity GO Molecular Function Annotations 2015 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NPM1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K94616959 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54579 layer 3 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06862 double outlet right ventricle MGI Mouse Phenotype Associations 2023 1.0 null tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.869233 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44366 RAB3A_KO_GDS2482_705_mouse_Cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K80921954 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21132 BRD-K51446586 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38194 BRD-A05883068 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48053 BRD-K65824451 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.09276 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62865 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.889963 Learning Disorders CTD Gene-Disease Associations 1.0 1.34576 intermediate stratum of r2BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00279 Lung adenocarcinoma_LUAD_TCGA-55-6978-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7067-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SF268 GDSC Cell Line Gene Expression Profiles 1.0 1.88132 periventricular stratum of isBL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20448 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.846712 NCIH522 CCLE Cell Line Gene CNV Profiles 1.0 2.08447 BRD-K27971671 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13385 Simple lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65639 LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null M059K CCLE Cell Line Gene CNV Profiles -1.0 -1.52605 BRD-K70057550 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18386 BRD-K19580273 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16366 ATF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HS-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K56032186 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83953 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null J82 CCLE Cell Line Gene CNV Profiles -1.0 -1.56517 HIF1A_NULL MUTATION_GDS1648_764_mouse_Hepatocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K37956279 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19686 BRD-K79555018 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05353 cellular amide metabolic process GO Biological Process Annotations 2015 1.0 null H3K27me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-A91823394 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23966 BRD-K00263786 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24704 transferase activity GO Molecular Function Annotations 2015 1.0 null SCC-9 GDSC Cell Line Gene Expression Profiles -1.0 -1.96915 Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YP-01A-21R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K87595216 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.01464 LNCAPCLONEFGC CCLE Cell Line Gene CNV Profiles -1.0 -2.48197 OVMANA CCLE Cell Line Gene CNV Profiles 1.0 1.43517 peptidyl-lysine acetylation GO Biological Process Annotations 2015 1.0 null SP in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07828 BRD-K63436213 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03161 SREBF1 ChEA Transcription Factor Targets 1.0 null TP63_01_202 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.3356 paraventricular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01943 HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.940074 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5333-01A-01R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K94115999 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16424 white matter of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37056 VZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.957132 Prostate adenocarcinoma_PRAD_TCGA-XJ-A83G-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K24035524 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.60742 mediodorsal nucleus of thalamus_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.54458 18614019-TableS4c GeneSigDB Published Gene Signatures 1.0 null r5 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00028 EFO-21 GDSC Cell Line Gene Expression Profiles -1.0 -1.46279 Folium-tuber vermis (VII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.09543 pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.022618 r9 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29313 BRD-K11420482 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.97622 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.98352 Culmen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.23675 BRD-K25081075 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47929 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Central lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.19479 ESR1_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K97748753 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.44558 regulation of gene expression GO Biological Process Annotations 2015 1.0 null BRD-K95735171 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55698 Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58119 BRD-K81960205 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10265 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.68332 SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32197 PPARA_KO_GDS2886_484_mouse_small intestine GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K85943445 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29909 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-AH-6897-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K73840377 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41801 BRD-K30236306 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.11215 BRD-K15800236 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59329 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.68737 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.82564 ELAVL1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K07484899 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11389 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cortex of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46193 Dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77528 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68317 TOP1 Hub Proteins Protein-Protein Interactions 1.0 null BRD-K60772078 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50977 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05772 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.73361 BRD-K51153795 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10682 superficial stratum of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14299 BRD-K72821236 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44478 EGR1-23403033-LIVER-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Hyperplasia CTD Gene-Disease Associations 1.0 1.47322 SBC-1 GDSC Cell Line Gene Expression Profiles 1.0 1.46871 BRD-K83754856 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64985 BRD-K90474764 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29247 intermediate stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76826 Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MIR222_KD_GDS4054_456_human_MCF7 breast cancer cells (fulvestrant-resistant) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40468 DDX21 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ESR1 ENCODE Transcription Factor Targets 1.0 null BT549 CCLE Cell Line Gene CNV Profiles -1.0 -1.44675 BRD-K10171338 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46581 17483316-Table2 GeneSigDB Published Gene Signatures 1.0 null Senescence_CNS - Brain - Hippocampus (MMHCC)_GSE5078 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.76646 OELE Achilles Cell Line Gene Essentiality Profiles 1.0 1.62599 mRNA_SOX17_20123909 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null BRD-K74040368 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21576 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.96797 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.828932 BRD-K80851151 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.55235 ZNF217 ENCODE Transcription Factor Targets 1.0 null IL21_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11858 CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31716 SNU216 CCLE Cell Line Gene CNV Profiles -1.0 -1.37481 H3K27me3_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K39617634 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68172 Liver Neoplasms CTD Gene-Disease Associations 1.0 1.93999 members GeneRIF Biological Term Annotations 1.0 null Orbital area, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09215 LNCAP Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00215 cuneate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.915465 Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32798 CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.962009 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K96389533 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75918 TCCSUP CCLE Cell Line Gene CNV Profiles -1.0 -1.49705 POLR2A_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null not applicable_asthma_GSE43696_369_mouse_bronchial epithelial cell GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QF-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K95952081 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.04444 superficial stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01023 layer 1 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1149 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.950005 organelle membrane GO Cellular Component Annotations 2015 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lobule III, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.45659 REST ENCODE Transcription Factor Targets 1.0 null HNRNPA2B1 Pathway Commons Protein-Protein Interactions 1.0 null HNRNPU Pathway Commons Protein-Protein Interactions 1.0 null SIN3A ENCODE Transcription Factor Targets 1.0 null BRD-A07195938 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.73083 FOXA1_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-VN-1203-2004(H5N1)_Day1-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.91319 BRD-A48478073 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39918 DHX9 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K29850806 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13474 liver BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MH-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLM1 CCLE Cell Line Gene CNV Profiles 1.0 1.69479 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K10191318 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33592 BRD-K24312231 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03059 BRD-K74324157 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38526 IOMMLEE CCLE Cell Line Gene Expression Profiles 1.0 1.53161 CUX1 ChEA Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A68949340 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12364 omphalocele MGI Mouse Phenotype Associations 2023 1.0 null BRD-K25485483 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.96217 BRD-K27653895 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00554 BRD-K29975122 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.19626 SALE CCLE Cell Line Gene Expression Profiles 1.0 1.51204 BRD-K85440939 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.797 Spinal nucleus of the trigeminal, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07146 TET1 ChEA Transcription Factor Targets 1.0 null tremors MGI Mouse Phenotype Associations 2023 1.0 null BRD-K40776502 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22232 OVISE Achilles Cell Line Gene Essentiality Profiles -1.0 -1.26127 UACC893 CCLE Cell Line Gene CNV Profiles -1.0 -1.70567 FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K83603369 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.03803 FGFR2_activemutant_59_GSE17916 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.99012 KARPAS-422 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71015 BRD-K71824916 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35342 BRD-K03243737 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47955 SW1088 CCLE Cell Line Gene Expression Profiles -1.0 -2.09711 ventrolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.51598 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32045 Lung squamous cell carcinoma_LUSC_TCGA-18-3419-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Poisoning CTD Gene-Disease Associations 1.0 1.09646 BRD-K76755209 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72882 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null superficial layers of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81861 Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1008 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.95605 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44926 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08322 CCK81 CCLE Cell Line Gene Expression Profiles 1.0 1.79738 Urogenital Abnormalities CTD Gene-Disease Associations 1.0 1.20229 Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61192 BRD-K34604637 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84461 intermediate stratum of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55642 nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38547 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05472 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.44355 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXB9_02_15 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.19265 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RL-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K06577881 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40621 Neoplasms CTD Gene-Disease Associations 1.0 1.04276 639-V GDSC Cell Line Gene Expression Profiles -1.0 -1.61053 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4340-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A19766589 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31198 CBX3 ENCODE Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Purkinje cell layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66765 dorsolateral isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3315 negative regulation of cell death GO Biological Process Annotations 2015 1.0 null BRD-K97256018 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05047 Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08277 ALVA31 BioGPS Cell Line Gene Expression Profiles 1.0 1.53542 biological regulation GO Biological Process Annotations 2015 1.0 null gastrulation GO Biological Process Annotations 2015 1.0 null BRD-K13526697 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15954 Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75643 MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TOP1 Pathway Commons Protein-Protein Interactions 1.0 null Presubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60818 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31892 ZNF217_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane region GO Cellular Component Annotations 2015 1.0 null Hypertension CTD Gene-Disease Associations 1.0 1.06116 MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.64663 KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886027 BRD-K36208388 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.04022 H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K70566686 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.93161 alpha-CP1 MotifMap Predicted Transcription Factor Targets 1.0 null ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.00727 BRD-K46742113 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26574 Liver Diseases CTD Gene-Disease Associations 1.0 1.9196 Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K83183132 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18723 SW1463 GDSC Cell Line Gene Expression Profiles 1.0 1.61082 herniated abdominal wall MGI Mouse Phenotype Associations 2023 1.0 null UBTF ENCODE Transcription Factor Targets 1.0 null REST_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null rosiglitazone_rattus norvegicus_gpl1355_gds3396 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null nucleus of the diagonal band, left, vertical division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38709 hsa-miR-4256 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 MAFK ENCODE Transcription Factor Targets 1.0 null HNRNPL Pathway Commons Protein-Protein Interactions 1.0 null dorsolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27127 BRD-K64970964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03034 precentral gyrus, right, inferior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2824 dexamethasone_rattus norvegicus_gpl1355_gse29912 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K86903429 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.71534 alar part of terminal hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3461 Fundus of striatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66264 BRD-K90793170 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01211 BRD-K44549496 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42041 BRD-K82674931 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00122 BRD-K66327237 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65148 lysine n-acetyltransferase activity, acting on acetyl phosphate as donor GO Molecular Function Annotations 2015 1.0 null BRD-K38617061 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19329 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K56562541 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.06772 parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33584 SET2 CCLE Cell Line Gene Expression Profiles 1.0 1.55469 BRD-K46560430 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26405 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superior colliculus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13605 dorsolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.889475 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F8-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.71915 HSF1_KD_GDS1733_751_human_HeLa cells - 0.5 Hour by siHSF1_1 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null positive regulation of gene expression GO Biological Process Annotations 2015 1.0 null SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.21943 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SF539 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60246 positive regulation of gene expression GO Biological Process Annotations 2023 1.0 null BRD-K77214724 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71829 Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56597 gastrulation with mouth forming second GO Biological Process Annotations 2023 1.0 null BRD-K83109105 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20132 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28523 BRD-K92444813 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4936 Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34367 cortex of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78579 BRD-K19387722 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22818 H2AFZ ENCODE Transcription Factor Targets 1.0 null Hepatomegaly CTD Gene-Disease Associations 1.0 1.99408 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6484-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.939204 SCC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.67498 H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CW-2 GDSC Cell Line Gene Expression Profiles 1.0 1.46439 primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.891429 HEL GDSC Cell Line Gene Expression Profiles 1.0 1.75063 acetyltransferase activity GO Molecular Function Annotations 2023 1.0 null COV362 CCLE Cell Line Gene Expression Profiles -1.0 -1.63484 lhx8_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.309439 p2 portion of the substantia nigra pars compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07898 intermediate stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26974 EZH2 ENCODE Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14804 BRD-K86925685 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13945 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12013 Lung adenocarcinoma_LUAD_TCGA-73-4676-11A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K60701773 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83363 BRD-K88707941 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4765 BRD-K54751293 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.42665 BRD-A14183911 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33729 posteroventral (inferior) parietal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02256 A-VN-1203-2004(H5N1)_Day1-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.01616 BRD-K00409424 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07387 BRD-K46074482 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.85047 membrane GO Cellular Component Annotations 2015 1.0 null nucleus of Darkschewitsch, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.79531 BRD-K09414286 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3099 BRD-K23840704 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.62391 Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.10347 BRD-K92981306 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.84081 BRD-K96265882 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12031 BRD-K37584517 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49029 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17153 BRD-K96379403 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09733 hindbrain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00243 BRD-K25952063 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41207 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3705 HEP3B217 CCLE Cell Line Gene Expression Profiles 1.0 1.63741 Bladder Urothelial Carcinoma_BLCA_TCGA-YF-AA3L-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K68970089 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07386 REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Fibrosis CTD Gene-Disease Associations 1.0 1.23806 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-CA-04-2009(H1N1)MA_Day1_22532695_GSE36328 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.30624 Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MJ CCLE Cell Line Gene CNV Profiles 1.0 1.32748 abnormal lung lobe morphology MGI Mouse Phenotype Associations 2023 1.0 null Cerebellum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49884 BRD-A85028244 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61252 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null BRD-K55220938 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54989 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.902394 BRD-K90111788 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03079 REST_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular protein metabolic process GO Biological Process Annotations 2015 1.0 null preoptic alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2969 H3K4me1_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-11A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06795 BRD-K34343777 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17779 BRD-K31407552 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05948 associate GeneRIF Biological Term Annotations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ASPC1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.59401 RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21565 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06716 Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null negative regulation of apoptotic process GO Biological Process Annotations 2015 1.0 null endoplasmic reticulum membrane GO Cellular Component Annotations 2015 1.0 null BRD-K72261386 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04348 lung BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.18447 H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923052 Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null peptidyl-lysine n6-acetylation GO Biological Process Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HT-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Simple lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73772 SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.90641 H3K4me1_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846653 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K35780971 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63662 BRD-K00048155 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22111 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13642 BRD-K03467766 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38237 BRD-K09895564 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41339 BRD-K72997741 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22338 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH2052 CCLE Cell Line Gene CNV Profiles 1.0 2.07255 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08028 BRD-K36096526 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11603 BRD-K79179851 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.03944 BRD-K14813771 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.22438 BRD-A03940741 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.3266 REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU5F1 ChEA Transcription Factor Targets 1.0 null BRD-K86111620 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54407 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25047 BRD-K33734659 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36951 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRY-22984422-TESTIS-RAT ChEA Transcription Factor Binding Site Profiles 1.0 null organic substance metabolic process GO Biological Process Annotations 2015 1.0 null BRD-A65592966 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.04658 BRD-K35923751 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06825 A2058 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.13192 BRD-K92570288 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31849 BRD-K87461415 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45538 superficial stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06862 ESR1_T47D_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K61072684 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64376 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16409 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26782 Congenital Abnormalities CTD Gene-Disease Associations 1.0 1.14166 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16583 BRD-K74245698 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06502 FOXA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64319 BRD-A98888138 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.87452 amyloid-beta metabolic process GO Biological Process Annotations 2023 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW403 CCLE Cell Line Gene Expression Profiles 1.0 2.58131 BRD-K95343362 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02557 Ulcerative Colitis_Peripheral blood mononuclear cell_GSE3365 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.48834 G120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923052 BRD-A56427952 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1141 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NH-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K09699976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31836 BRD-K90902537 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50502 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.16387 TET1-21451524-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K95688447 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.70927 BRD-K16937802 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35491 PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K31834149 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29502 Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77517 BRD-K57969360 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61758 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.887724 BRD-K79517375 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5924 biological_process GO Biological Process Annotations 2015 1.0 null Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47983 intermediate white layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01286 Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.79711 BRD-K52123365 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.16307 BRD-K95941120 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.07221 periventricular stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37135 tremors IMPC Knockout Mouse Phenotypes 1.0 null BRD-K09144377 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0341 BRD-K85996308 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39036 BRD-K86358396 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.75855 Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A42536341 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11012 mRNA_EP400_22196727 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null REST_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of apoptotic process GO Biological Process Annotations 2015 1.0 null regulation of cell death GO Biological Process Annotations 2015 1.0 null posterior triangular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2156 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.63081 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.89043 internal protein amino acid acetylation GO Biological Process Annotations 2015 1.0 null HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.54689 BRD-K67146164 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21867 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37427 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.57684 biochemical GeneRIF Biological Term Annotations 1.0 null BRD-K22338979 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11655 BRD-K10989739 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12104 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25538 mRNA_KAT5_22196727 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null hsa-miR-4450 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 BRD-K76763044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05613 GNAT domain InterPro Predicted Protein Domain Annotations 1.0 null FOSL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_EOMES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null BRD-K66270896 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.94134 BRD-K66187822 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59627 dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.956908 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21965 BRD-A37105798 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.18165