association	dataset	threshold value	standardized value
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inner mitochondrial membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.589
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82876
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4381
BA-77-US35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.874269
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5531
NDUFC2	Pathway Commons Protein-Protein Interactions	1.0	null
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.805372
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60076
NRF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO824	DepMap CRISPR Gene Dependency	1.0	4.76363
SLC25A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03246
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902812
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	5.93484
abnormality of skin adnexa	HPO Gene-Disease Associations	1.0	null
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
mitochondrial membrane part	GO Cellular Component Annotations 2015	1.0	null
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_ATF1-gene_ATF1	Rummagene Transcription Factor Associations 2026	1.0	null
hyperreflexia	HPO Gene-Disease Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pavement epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1359
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.238054
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74918
disease	GWASdb SNP-Disease Associations	1.0	0.023906
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22397
Lung squamous cell carcinoma_LUSC_TCGA-39-5036-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart_5a	HPA Tissue Sample Gene Expression Profiles	1.0	2.27259
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23825
9798_BUD23_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.04676
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.59
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	1.51101
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00859
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55812
Electron Transport Chain(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21095
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE239578_0_v_6_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3467
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05198
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02018
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63696
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I4-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mitochondrial respiratory chain complex I	GO Cellular Component Annotations 2023	1.0	null
Perturb_811_KO_NRIP1_SRP327958	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.37869
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
JHH2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51815
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66349
Metallochaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09668
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891727
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4482
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-69-HJ13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.05101
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0195
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18491
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cervical mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.228234
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71346
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984815
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8444
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39827
mitochondrial inheritance	HPO Gene-Disease Associations	1.0	null
Peripheral blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.569
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0503
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06388
uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.407172
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31238
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75504
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941536
Olfactory lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.145
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933596
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sulfide	HMDB Metabolites of Enzymes	1.0	null
Brachial plexus lesion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Enterovirus 71_8Hour_None_GSE15323	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.10008
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20899
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934171
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKLU1	CCLE Cell Line Gene Expression Profiles	1.0	2.42042
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886342
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EC-98-KI28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278111
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FGFR1_mutant_25_GDS4046	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.45415
19192944-TableS4	GeneSigDB Published Gene Signatures	1.0	null
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390179
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.921274
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.492404
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSS008	DepMap CRISPR Gene Dependency	1.0	3.97531
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70276
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873794
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Endocervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.042809
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMRT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7505
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073356
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mitochondrial ATP synthesis coupled electron transport	GO Biological Process Annotations 2023	1.0	null
anaplastic large cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.571107
colon_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.832335
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	2.05555
BD-61-OO16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214165
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49043
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE62843,GSE64371_2_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8208823-mmc2.xlsx-CDX2-KO_mesenchymal_DEG-feature_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4996
Cortical granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inherited metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09742
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
infantile onset	HPO Gene-Disease Associations	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34167
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2445
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Esophageal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
BT16	DepMap CRISPR Gene Dependency	1.0	3.19174
INA-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30379
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3656
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883712
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056635
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39525
BORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1895
Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CyPPA	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.71
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85793
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-2.08677
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	3.37421
MC-CAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.989913
Cytochrome b6f complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
gata4_16914500_e9dot5_atrioventricular_canal_lof_mouse_gpl1261_gds3663	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.010657
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.735725
NCI-H2228	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.92981
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75529
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UO-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.9013
GSE211128_3_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
S0-EE-XMXE_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227459
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05137
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.825604
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59566
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A733-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.907535
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63161
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
TM4SF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31353
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03225
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2342	CCLE Cell Line Gene Expression Profiles	1.0	1.71813
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18362
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.98322
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24588
HBS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36943
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51624
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.181524
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.53258
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPN-2726-SM-2I5H4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36322
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11565
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01223
DA-27-BW40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3762
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852193
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial Complex I Deficiency	DisGeNET Gene-Disease Associations	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0863
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JT-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.371599
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.27463
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.06883
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51538
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9323564__F16	PFOCR Pathway Figure Associations 2024	1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212586
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10708
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40364
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3451-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MFE319	DepMap CRISPR Gene Dependency	1.0	4.00628
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38153
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A78R-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27135
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.074
GOLPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50677
Nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.876
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07618
Mitochondrial crista junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07952
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_XAV-939_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128441
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35612
SLC45A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10527
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Placenta	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.74927
8651_TAF10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.642074
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.756
GTEX-TMMY-1726-SM-4DXTD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843511
Electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042056
CHD1	ENCODE Transcription Factor Targets	1.0	null
LS411N	DepMap CRISPR Gene Dependency	1.0	2.3861
abnormal respiratory system morphology	HPO Gene-Disease Associations	1.0	null
CALHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10763
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.93511
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37736
abnormal cns myelination	HPO Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7465-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Scotoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17864
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11801
STAT5A	ENCODE Transcription Factor Targets	1.0	null
MRPL15	Pathway Commons Protein-Protein Interactions	1.0	null
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910081
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09006
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80059
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.265
Type 1 diabetes mellitus_Thymic epithelial cell_GSE11	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.20203
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-1226-SM-4AT65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57027
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.65524
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.988626
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.07069
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981083
ABCD1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96615
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.2978
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15128
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
SARS-dORF6_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.44229
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.573738
ROS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
MET_knockout_252_GSE30651	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.3023
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02806
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05238
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36305
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46329
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
3e1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08888
LS1034	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.03112
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20311
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089577
NDUFS6	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8851354-Table_5.xlsx-Ruxolitinib_reg_FD-bound-Supplementary_Table_5_Genes_regulated_by_ruxolitinib_that_are_FUS-DDIT3_targets_in_MLS_402-91_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13727
RCOR1	ChEA Transcription Factor Targets	1.0	null
PA-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.17335
Amyotrophic neuralgia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.00504
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36305
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53142
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EN	DepMap CRISPR Gene Dependency	1.0	3.79143
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13143
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65404
cellular respiration	GO Biological Process Annotations 2023	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47619
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHPG-1026-SM-3NMBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22068
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41644
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98764
NC-27-AD53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289635
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-8501-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.865
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953364
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16895
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NFIA_Deficiency_GDS2775_639_mouse_Embryonic brains (at E18)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hepatic necrosis	HPO Gene-Disease Associations	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_6_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34586
105_ACTG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.57273
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06679
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.939851
pioglitazone_rattus norvegicus_gpl341_gse21329	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Chronic progressive external ophthalmoplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
ZFX-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of movement	HPO Gene-Disease Associations	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0266
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0331
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837926
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
10029_ZC3H8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.525623
abnormality of the retina	HPO Gene-Disease Associations	1.0	null
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03316
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02988
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TMEM98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16041
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240276
GTEX-N7MS-0626-SM-2YUN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914733
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DU145_PROSTATE	CCLE Cell Line Proteomics	1.0	4.64542
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6578
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HM-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mitochondrial part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_6988_OE_Erbb2_SRP245626	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NDUFB11	Pathway Commons Protein-Protein Interactions	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.10033
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03225
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.544067
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908041
TIM22 mitochondrial import inner membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.596
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62667
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.73109
mitochondrial membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998156
DKMG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8825
oc316	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05952
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14702
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08417
NDUFS7	Pathway Commons Protein-Protein Interactions	1.0	null
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pioglitazone_homo sapiens_gpl570_gds4132	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gata3_22922362_treg_cd4poscd25posyfppos_lof_mouse_gpl8321_gse39864	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.547443
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23727
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23479
vitamin e_mus musculus_gpl1261_gse42813	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.062
NELFA-20434984-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.27829
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041283
pace of progression	HPO Gene-Disease Associations	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68442
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCA7_Knock-in_GDS3545_560_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NDUFV1	Pathway Commons Protein-Protein Interactions	1.0	null
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3656
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial complex I deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.984
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.536967
LGI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39423
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31628
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50881
Lymphoblastoid cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.369
NCIH727	DepMap CRISPR Gene Dependency	1.0	2.36208
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70031
Integral component of mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-87-SF89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.322314
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.059
ATF2	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76687
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08805
Prostate adenocarcinoma_PRAD_TCGA-2A-A8W1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOMM22	Pathway Commons Protein-Protein Interactions	1.0	null
15297395-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Increased Csf Lactate	DisGeNET Gene-Phenotype Associations	1.0	null
Ezh2_Deficiency_GDS4309_364_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17431
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15408
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory gaseous exchange	GO Biological Process Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.952559
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-600-ZNF174_ZNF174	Rummagene Transcription Factor Associations 2026	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44568
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23445
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092471
T-lymphoblastic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.369
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50486
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989222
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53223
PACADD188	DepMap CRISPR Gene Dependency	1.0	2.32121
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266697
K562_Linifanib_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127441
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
8651_TAF10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.622982
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867993
SW1417	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.93198
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32987
colorectal cancer cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.89565
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11611
muscle	GTEx Tissue Gene Expression Profiles	1.0	1.20332
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31173
NCIH838	CCLE Cell Line Gene Expression Profiles	1.0	2.17009
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0793
Mitochondrial creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
5470_NAT10_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.05853
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.28629
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8229_SNRPD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.628473
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6AW-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
yy2_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.051976
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NADH dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.677
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905638
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.689179
IC-79-JZ26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214949
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.59808
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26768
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.58214
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2559
Perturb_14661_KO_Insm1|Pax6_ERP127840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.7284
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2771-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_8_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RA-42-CM42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22859
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.7789
oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.125057
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88691
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15952
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.19582
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE140965_2_v_3_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PSMD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.43269
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49678
KYSE410	CCLE Cell Line Gene Expression Profiles	1.0	1.37647
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19326
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314772
mitochondrial respiratory chain	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WQUQ-1326-SM-3MJFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20783
Nuclear type mitochondrial complex I deficiency 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.085
HT29_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.93319
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
zinc acetate_homo sapiens_gpl570_gds1617	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ndufa3	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7150-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4418-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
5532_NDUFA12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-1.11244
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12881
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54566
7505_RPS16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.621589
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972024
Daptomycin_A498	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00616242
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03773
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05383
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_5_TbID_-biotin_ERM_proteo-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SKLU1_LUNG	CCLE Cell Line Proteomics	1.0	7.70258
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15499
CEBPD	ENCODE Transcription Factor Targets	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7441_RPL17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.574861
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3608
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.85
CSNK2B	MSigDB Cancer Gene Co-expression Modules	1.0	null
mode of inheritance	HPO Gene-Disease Associations	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47817
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.51043
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954503
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57937
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3448
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.392568
TAF1	ENCODE Transcription Factor Targets	1.0	null
Nuclear type mitochondrial complex I deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
PMC6580171__F4	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25829
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69895
Hyperplasia	CTD Gene-Disease Associations	1.0	1.39646
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28931
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XYKS-1226-SM-4BRVI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852519
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6089552-oncotarget-09-31018-s004.xlsx-compound_targets_chip_rnaseq-Chip-seq_derived_EWS-FLI1_targets_Bilke_et_al_2013_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Pineal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.403
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.1124
neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32205
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Asthma, allergic_Lung Tissue_GSE3184	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.52141
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7521272__F4	PFOCR Pathway Figure Associations 2024	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71786
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42434
mitochondrial ATP synthesis coupled electron transport	GO Biological Process Annotations 2025	1.0	null
mitochondrial inner membrane	GO Cellular Component Annotations 2025	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028202
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTC642	DepMap CRISPR Gene Dependency	1.0	2.40614
GSE208141,GSE208142_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.01471
Mitochondrial encephalomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912785
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162908
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6527
Adrenal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.043
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42227
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_10327_KO_Anxa1_SRP377197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.78412
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
troglitazone_rattus norvegicus_gpl341_skeletal muscle_gds3850	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Progressive Cerebellar Ataxia	DisGeNET Gene-Disease Associations	1.0	null
PMC11258892-NIHMS2003533-supplement-MMC6.pdf-34-ZNF211_ZNF211	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60722
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SARS-BatSRBD_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.0877
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08328
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.957661
16489042-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510992
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200176
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03698
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7179
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5596
mitochondrial membrane	GO Cellular Component Annotations 2025	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0346
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7B-Table_S7B_Frontal_cortex_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09947
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.514428
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72439
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.64735
NRF1	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967023
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32861
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.32902
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16814
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J2-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06939
NDUFV3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.550771
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44867
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1	MSigDB Cancer Gene Co-expression Modules	1.0	null
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.825056
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HAL-01	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.79193
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10322
CHD7	ENCODE Transcription Factor Targets	1.0	null
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
b65	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
FKBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88146
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08745
A549_Aurora A Inhibitor I_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146124
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypertrichosis	HPO Gene-Disease Associations	1.0	null
CD-16-KY17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09267
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
MKN1	CCLE Cell Line Gene Expression Profiles	1.0	2.02996
QGP1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46472
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42567
NADH	DrugBank Drug Targets	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
SUDHL4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.89048
MOLT-4 cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.369
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5865
PMC7521272__F4	PFOCR Pathway Figure Associations 2023	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.14624
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37498
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0527
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.629499
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	4.43935
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16603
K562_G007-LK_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174891
NCIH1299	CCLE Cell Line Gene Expression Profiles	1.0	1.49116
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42049
NDUFA8	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00917
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6194
DB	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.75195
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39189
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.169
USF2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.913538
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74622
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIK3CG_knockdown_96_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.59946
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964138
NELFE	ENCODE Transcription Factor Targets	1.0	null
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66112
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal csf lactate level	HPO Gene-Disease Associations	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-Each_THP1_Pulldown_Expt_Targets-Unnamed_5_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6454
WHSC1	ENCODE Transcription Factor Targets	1.0	null
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38721
RVH-421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NDUFA9	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT55	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.99567
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47115
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49324
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08888
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99106
SP4	ENCODE Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00041
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80868
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9826
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02287
Synovial sarcoma_Synovial Membrane_GSE6461	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.82973
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20535
Skeletal Muscle Atrophy	DisGeNET Gene-Phenotype Associations	1.0	null
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64501
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.10217
GSE255432_7_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.63771
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913309
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Retrograde endocannabinoid signaling	KEGG Pathways 2026	1.0	null
Mitochondrial metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.5
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8044433-mmc4.xlsx-Sheet1-Subacute_LPS_Microglia_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880948
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908041
Lung adenocarcinoma_LUAD_TCGA-50-5045-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
c2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.35681
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43886
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210825
GSE123836_2_v_3_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IA-65-QX27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221978
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
t69-brown-adipose_male_8w	MoTrPAC Rat Endurance Exercise Training	-1.0	-5.26918
pigmentary retinopathy	HPO Gene-Disease Associations	1.0	null
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.89
KLE	DepMap CRISPR Gene Dependency	1.0	4.56248
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054135
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR0B1	ChEA Transcription Factor Targets	1.0	null
GSE202434,GSE202438_8_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
19643001-Additional-File2	GeneSigDB Published Gene Signatures	1.0	null
SUP-M2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NB-17-SQ59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.554771
Mavorixafor	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.54
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93968
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965912
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMRC20_KIDNEY	CCLE Cell Line Proteomics	1.0	2.38713
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68889
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4238
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphocytic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.369
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10604
abnormal involuntary eye movements	HPO Gene-Disease Associations	1.0	null
H3K4me1_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60096
GSE226114,GSE226116_2_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
Mitochondrial metabolism disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14542
VMCUB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48021
abnormality of the hair	HPO Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LV-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALL-SIL	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.05824
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01255
NADH dehydrogenase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20069
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.62254
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27103
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863432
Electron Transport Chain(Mus musculus)	WikiPathways Pathways 2014	1.0	null
proton motive force-driven mitochondrial ATP synthesis	GO Biological Process Annotations 2025	1.0	null
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94082
mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.84
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227463
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215929
T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.463
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21304
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.84031
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04427
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53749
ACHN	CCLE Cell Line Gene Expression Profiles	1.0	1.47646
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26229
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7117
u87	HPA Cell Line Gene Expression Profiles	-1.0	-1.55876
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
AC-50-FR41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.355307
SKNFI	CCLE Cell Line Gene CNV Profiles	1.0	1.51167
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.92517
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.411039
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.934177
CHD1	ChEA Transcription Factor Targets	1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827848
progressive disorder	HPO Gene-Disease Associations	1.0	null
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978073
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053457
ChIP_ESRRB_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.75722
rosiglitazone_mus musculus_gpl8321_gds4021	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56893
Lung squamous cell carcinoma_LUSC_TCGA-33-4582-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.60291
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.589218
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21304
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
respiratory chain complex iii	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.23776
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17381_Mut_Zc3h12a_SRP328189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.44859
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11799
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233661
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02848
GSE139966_1_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14144
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.62357
GTEX-WFON-0626-SM-4LVLX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900801
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12289
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rhombomere 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03225
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_6308_KD_PUM1_SRP396076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.6659
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2168
SUDHL4	CCLE Cell Line Gene Expression Profiles	1.0	1.72592
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
vas efferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31877
GSE137144_5_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Integral component of mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6854
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26601
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.587563
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bronchial epithelial cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.618
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NADH	HMDB Metabolites of Enzymes	1.0	null
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.19434
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01233
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842704
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06743
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.841151
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.889
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13305
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328994
SU-DHL-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AB-84-PK04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422354
JVE253	DepMap CRISPR Gene Dependency	1.0	2.21738
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060424
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05488
CD-20-MH57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235981
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33024
WC-09-GD62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263233
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.37068
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC4784386__F4	PFOCR Pathway Figure Associations 2024	1.0	null
PMC6379092-elife-39598-supp2.xlsx-KLF2_target_genes-Complex_I_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of acid-base homeostasis	HPO Gene-Disease Associations	1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856768
ZNF274	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89742
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05564
Nucleus lentiformis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.045
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73878
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Metabolism	Reactome Pathways 2014	1.0	null
organelle inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-7_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.904004
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49029
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.86098
Trichuriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
NDUFS3	Pathway Commons Protein-Protein Interactions	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.41468
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053358
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05348
MK 886	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.9926
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1386
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902632
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	3.83201
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE258991_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.66583
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23869
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
NFE2	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03225
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34019
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16313
CC-14-WK34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324085
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62037
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33028
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852158
RUNX3	ENCODE Transcription Factor Targets	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72623
ndufa5	GeneRIF Biological Term Annotations	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7519-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F0-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21411
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.01423
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gliosis	HPO Gene-Disease Associations	1.0	null
Paragigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02061
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.09646
GSE119978,GSE180930_0_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0761
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.80473
GSE249893_1_v_0_tfam_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.013
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.908
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42672
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.61241
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25475
Perturb_11870_KO_Igf1r_SRP091724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.01598
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09428
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20611
PMC12658036-41598_2025_25964_MOESM5_ESM.xlsx-Sheet1-Supplementary_Table_1_The_list_of_546_proteins_specific_to_pLV3-CMV-AR-TurboID_H2O2_group_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.088
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26576
heart_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.16675
CA-42-YI34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.452036
Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency	DisGeNET Gene-Disease Associations	1.0	null
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15972
PARD6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51823
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96447
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530752
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35392
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.645
Myelencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
ESRRB-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of hindbrain morphology	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.892956
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.944869
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44242
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1747
EBC1	CCLE Cell Line Gene Expression Profiles	1.0	1.47302
QA-07-KC40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267092
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41105
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965855
Fe2+	HMDB Metabolites of Enzymes	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81181
Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RP1_KO_GDS1845_190_mouse_Retinas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FGFR1_knockdown_94_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.68223
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311483
KMM1	CCLE Cell Line Gene Expression Profiles	1.0	1.88833
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mitochondrial DNA depletion syndrome 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	3.38572
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08212
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21803
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40U-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205164
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00124
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56124
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04187
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NCI-H226 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16319
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.51002
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60076
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926871
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.945675
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
respiratory chain	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.281821
ELF1	ENCODE Transcription Factor Targets	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30542
Prion disease	KEGG Pathways 2026	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.660711
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	2.04766
paclitaxel_homo sapiens_gpl570_gse19136	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Leigh Disease	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
715_AURKB_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.06028
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407073
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880182
ATF3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873923
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.07074
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.51709
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic islet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.255
connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065003
C8166	DepMap CRISPR Gene Dependency	1.0	5.10977
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Blood cancer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.369
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33071
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.15995
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26712
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02669
DC-43-KF54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34208
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24379
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65977
ERG	ChEA Transcription Factor Targets	1.0	null
SNU201	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4686
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36305
necessary	GeneRIF Biological Term Annotations	1.0	null
4908_MCOLN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.22875
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.93293
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59382
functional abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7945
PMC6319725-pone.0204197.s006.xlsx-Table_S2-S2_TABLE_-_Operon_Expression_and_SOM_clustering_data_for_Gene_Set_identified_by_ANOVA_p_0_005_1005_genes_FDR_8_8_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-5781-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918012
MEK_INHIBITION_GDS5029_279_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DEL	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.51026
GTEX-V955-0326-SM-4JBGV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05936
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11185
mitochondrial part	GO Cellular Component Annotations 2015	1.0	null
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.396
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatic coma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78724
GSE126463_6_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06676
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal pyramidal signs	HPO Gene-Disease Associations	1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12881
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124084
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10535
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20742
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4335056-pone.0116726.s005.xlsx-X-ChIP_NOT_TX100_QE-GENE_Official_symbol_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
8416_SRP68_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.50019
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028221
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844314
myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238406
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03993
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MONOMAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05986
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.82327
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09736
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15408
t55-gastrocnemius_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	1.38384
IGR37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34515
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93835
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
respiratory chain	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.227752
AA-46-GL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367909
ATF3	ENCODE Transcription Factor Targets	1.0	null
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-5337-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07547
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12486367-Supplementary_Data2.pdf-468-GATA5_GATA5	Rummagene Transcription Factor Associations 2026	1.0	null
Neurosphere_Cultured_Cells_Cortex_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.13556
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85065
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58232
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.998783
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1693	CCLE Cell Line Gene Expression Profiles	1.0	1.6673
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11524
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5194
retinal pigment epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.46766
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44867
A549_Clevudine_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120541
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Mucolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
1395_CDC26_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.984128
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_UP_NR2F1_ind_UP-NR2F1_Ind_UP_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43832
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73033
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pons	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.088
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF3I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02964
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12888
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93918
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05522
OC-41-DF58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202773
Gitter cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
DAOY_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.9235
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18274
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849229
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NV-128	DGIdb Drug Targets 2026	1.0	0.35288
Weight Loss	CTD Gene-Disease Associations	1.0	1.38156
HOXC9	ChEA Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47T-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMEpC cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.962672
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40058
vitamin c_mus musculus_gpl1261_gse37676	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mcf7	HPA Cell Line Gene Expression Profiles	1.0	1.02426
lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.698625
GSE199606_5_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
clinical modifier	HPO Gene-Disease Associations	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
SW-480 cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.39937
ASH2L	ChEA Transcription Factor Targets	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.68876
KIJK	DepMap CRISPR Gene Dependency	1.0	2.51714
ae3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33422
2543_EIF2S3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.581787
Cytotoxic T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.294
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRB-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
increased serum lactate	HPO Gene-Disease Associations	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05966
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19921
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42567
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.714914
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28415
icSARS CoV_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.74092
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4258
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1514
t30-blood-rna_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	5.33548
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15877
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.556079
RELA	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67183
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34089
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.830314
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249701
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.51582
NDUFS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE120595_0_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX2	ChEA Transcription Factor Targets	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923924
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204374
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-2.23134
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980252
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183335,GSE183351_3_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45897
nadh dehydrogenase activity	GO Molecular Function Annotations 2015	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.0346
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08086
Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.446931
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23986
retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.829872
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14883
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68887
Mitochondrion	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
mantle zone of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01822
PMC10898050-12967_2024_4947_MOESM2_ESM.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_between_the_TCF7_CD8_memory_T_cells_and_the_other_memory_CD8_T_cells_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989382
Tricarboxylic acid cycle enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.524
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM1S	DepMap CRISPR Gene Dependency	1.0	2.26035
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33582
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836085
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U8-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rosiglitazone_mus musculus_gpl1261_gse11343	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065358
NDUFA5	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t30-blood-rna_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	4.42317
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893701
Orbital cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
GTEX-XXEK-2026-SM-4BRVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886458
CHD2	ENCODE Transcription Factor Targets	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GSE126463_0_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71073
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24613
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04812
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13243
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75658
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.477346
GSE239651_1_v_0_ispinesib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Decreased Activity Of The Pyruvate Dehydrogenase Complex	DisGeNET Gene-Phenotype Associations	1.0	null
GSE190384,GSE190386_2_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.853732
Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-12_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
cytochrome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.115015
PMC6580171__F4	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06135
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1966
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841789
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945201
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03826
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42937
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64274
neurological speech impairment	HPO Gene-Disease Associations	1.0	null
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07576
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.33844
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60892
NRF1	JASPAR Predicted Transcription Factor Targets	1.0	null
abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.826787
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147943_4_v_6_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Pathways of neurodegeneration - multiple diseases	KEGG Pathways 2026	1.0	null
TGFBR2_knockout_293_GSE46211	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.91078
Mitochondrial iron-sulfur cluster assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NADH dehydrogenase (ubiquinone) activity	GO Molecular Function Annotations 2023	1.0	null
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	6.13268
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2064
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190384,GSE190386_6_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
Phosphorylase kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1067
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8627
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204203
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
XE-29-LT20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24386
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01634
MDA-MB-453 cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.21708
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05081
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U87MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91329
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFB7	Pathway Commons Protein-Protein Interactions	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057095
sensorineural hearing impairment	HPO Gene-Disease Associations	1.0	null
PMC4487811-mmc3.xlsx-siRE_enriched_geneLists-siRE_occupancy_pattern_gene_lists_after_RUNX1_ETO_knock_down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
ip94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.531
PMC10244410-41467_2023_39054_MOESM5_ESM.xlsx-PIE-LIN28B-GeneSymbol_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.753
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41957
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13242
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.541026
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923616
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924979
Severe Intellectual Disability	DisGeNET Gene-Disease Associations	1.0	null
TDRD3-21172665-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Coronary artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.85
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46059
Embryonic brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.244
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal fear/anxiety-related behavior	HPO Gene-Disease Associations	1.0	null
biogenesis	GeneRIF Biological Term Annotations	1.0	null
GTEX-RU1J-0826-SM-46MUU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83832
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
6793_PRPF31_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.516416
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33309
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.389671
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861811
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.480505
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04391
PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.83693
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12881
UA-39-TN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.462585
NCIH838	CCLE Cell Line Gene CNV Profiles	1.0	2.19814
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08328
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.534735
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
ACTG1	MSigDB Cancer Gene Co-expression Modules	1.0	null
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02061
FLT1_knockdown_111_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.00686
nadh dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.2236
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SS-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71545
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58184
Ophthalmoplegia	DisGeNET Gene-Phenotype Associations	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8893
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.822
nadh dehydrogenase complex	GO Cellular Component Annotations 2015	1.0	null
Thalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.401
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37638
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03662
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085221
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832307
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
electron carrier activity	GO Molecular Function Annotations 2015	1.0	null
type iii intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.281453
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35589
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PSME1	MSigDB Cancer Gene Co-expression Modules	1.0	null
hnf4a_16714383_e18dot5_liver_lof_mouse_gpl1261_gds1916	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	2.15066
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.14624
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059694
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00855
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835987
CHK1_KD_GSE54267_672_human_U2OS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07902
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19811
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-10_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20803
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11084
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934426
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum (corpus striatum)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01822
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933152
KRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87305
MYC	ChEA Transcription Factor Targets	1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
hsa-miR-377	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
t58-heart_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.4024
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40859
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86436
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYK_druginhibition_284_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.06075
MAFF	ENCODE Transcription Factor Targets	1.0	null
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE115395_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MPV17	Pathway Commons Protein-Protein Interactions	1.0	null
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukodystrophy	DisGeNET Gene-Disease Associations	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.889
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
respiratory chain complex i	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.629465
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30583
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-KT-A74X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ES8	DepMap CRISPR Gene Dependency	1.0	2.19622
SARS-dORF6_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.37486
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-VN-1203-2004(H5N1)_Day1-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.24211
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.721563
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-5_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849935
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62215
Acute Myeloid Leukemia_LAML_TCGA-AB-2939-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurodevelopmental abnormality	HPO Gene-Disease Associations	1.0	null
CCRF-CEM	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.40594
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.08397
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30334
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826981
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.245685
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874042
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68239
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824812
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the fundus	HPO Gene-Disease Associations	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08925
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04052
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32902
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32923
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910849
TIA1_KO_GSE54418_262_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07426
Caudoputamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05569
Optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
Respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.985
mitochondrial membrane	GO Cellular Component Annotations 2023	1.0	null
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.573006
MAPK14_knockout_13_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.61963
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85046
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11624
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
1424_CDK12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.539509
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825983
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2325
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT1197	DepMap CRISPR Gene Dependency	1.0	2.46659
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
Adenocarcinoma of lung_Lung Tissue_GSE1037	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.73068
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944965
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrion	GO Cellular Component Annotations 2015	1.0	null
MFE296	DepMap CRISPR Gene Dependency	1.0	7.17248
TP63	ChEA Transcription Factor Targets	1.0	null
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882424
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.83349
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HIPK2_knockdown_106_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.46327
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926991
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NDUFS2	Pathway Commons Protein-Protein Interactions	1.0	null
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53592
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11002
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62018
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287931
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35975
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.670878
FOXA1	ENCODE Transcription Factor Targets	1.0	null
rectum	HPA Tissue Gene Expression Profiles	1.0	0.830898
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA4	ChEA Transcription Factor Targets	1.0	null
VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE	ChEA Transcription Factor Targets 2022	1.0	null
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.852607
CTCF_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63924
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3935
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12964
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
APEX1	MSigDB Cancer Gene Co-expression Modules	1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.43087
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.988422
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.990589
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845765
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neurodegeneration with brain iron accumulation 2a	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03767
Cingulate cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.28
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51036
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40902
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18517
PMC7387553-41467_2020_17477_MOESM4_ESM.xlsx-B_LPS-stimulated_myeloid_cells-Cis-eQTLs_in_LPS-stimulated_myeloid_cells_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04391
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46695
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
Dystonia	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-1305	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28931
placenta praevia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.42104
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12718
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12085
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77728
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oxidative phosphorylation	GO Biological Process Annotations 2023	1.0	null
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44079
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468436
YE-55-YX75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20803
ZFP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12112
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Helper T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.463
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2676
16651409-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908041
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.7499
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0199
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.176
JL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99053
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04393
SLC39A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02173
PMC11465086-mmc2.xlsx-Table_ES_1_markers_c0_LPS_Vs_Co-Gene_Expression_Data_1_markers_c0_LPS_Vs_Control_related_to_Figure_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
569_ASB8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.567314
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06388
MEF2A	ChEA Transcription Factor Targets	1.0	null
CHD1-19587682-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49529
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841669
CLDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02305
ROCK2_knockdown_157_GSE34769	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.7742
GSE157050,GSE157051_2_v_9_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850909
7455_RPL27_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.13931
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
abnormal emotion/affect behavior	HPO Gene-Disease Associations	1.0	null
aerobic respiration	GO Biological Process Annotations 2025	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
GATA2-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29781
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_H_sapiens_970_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16351
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26601
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.923329
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053449
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38055
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858441
mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270214
Mitochondrial ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.72
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20645
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17156
oxidative phosphorylation	KEGG Pathways	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CA-23-BW20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319068
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884428
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37376
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.03787
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34947
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscle Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
PMC11033278__F8	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09446
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7444_RPL19_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.521743
Nicotine addiction_Ganglioneuroblastoma_GSE11208	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.12404
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.963388
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486523
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the lung	HPO Gene-Disease Associations	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34381
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95754
Adenocarcinoma of lung_Lung Tissue_GSE11969	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.60103
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinothalamic tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC4398389__F1	PFOCR Pathway Figure Associations 2023	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927304
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224069
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.944402
Cyclin B1-CDK1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
kidney	HPA Tissue Protein Expression Profiles	-1.0	-0.735725
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42567
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04165
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mitochondrial respiratory chain complex i	GO Cellular Component Annotations 2015	1.0	null
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3993
conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.426109
JA-85-SW39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244687
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3906
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17258
Hypertrichosis	DisGeNET Gene-Disease Associations	1.0	null
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
subunits	GeneRIF Biological Term Annotations	1.0	null
USP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51316
Neostriatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
PMC6781638__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2204
Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_61_KO_Usp16_SRP271781	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.48704
Mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.121
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.4169
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03368
GSE75976_3_v_4_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CYC1	Pathway Commons Protein-Protein Interactions	1.0	null
heterogeneous	HPO Gene-Disease Associations	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906987
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77475
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
Myocardial infarction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ray floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.6243
YE-46-YA12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310107
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2176
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45838
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
GSE193588_1_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
mitochondrial membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
STAT1	ChEA Transcription Factor Targets	1.0	null
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06408
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03893
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879029
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980252
Infertility, Male	CTD Gene-Disease Associations	1.0	1.24056
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3192
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CD-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246461,GSE246463_5_v_0_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852193
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-18-FP00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399377
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37141
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849783
Mitochondrial complex I deficiency	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19305
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7039-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157594_5_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2825-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
acidosis	HPO Gene-Disease Associations	1.0	null
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.518072
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.20503
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Olfactory bulb	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.145
17724462-TableS1	GeneSigDB Published Gene Signatures	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99775
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.31198
SNU216	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01317
OCI-AML2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.869754
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
LNCaP cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.41635
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.90602
HCT15_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.41124
TEAD4	ENCODE Transcription Factor Targets	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1028
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70951
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.959671
Inflammation	CTD Gene-Disease Associations	1.0	1.13621
Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878161
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Succinate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.672
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JB-89-SI60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221088
NK-92MI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
7438_RPL14_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.620565
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-2.06096
glandular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.411251
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06908
OC-314	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.16508
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862271
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05296
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
CBX3_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRAK4_knockout_41_GSE12124	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.6678
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44303
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979513
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	3.00081
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31408
nadh dehydrogenase complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ahr_19454665_epidermal_langerhans_cell_lof_mouse_gpl339_gds3575	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-9.38E-4
EEF1AKMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09624
r7 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03225
respiratory electron transport chain	GO Biological Process Annotations 2015	1.0	null
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00255
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57728
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.425344
Necrosis	CTD Gene-Disease Associations	1.0	1.55648
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10388
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.17728
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06952
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88953
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065531
CDK7_knockdown_124_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.7145
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MK-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE100217_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal myelination	HPO Gene-Disease Associations	1.0	null
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05674
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71545
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937608
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0343
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049618
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865112
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
emotional lability	HPO Gene-Disease Associations	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.318205
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24521
9454_TXNIP_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.60319
LC1SQSF	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82854
Respiratory chain complex I (lambda subunit) mitochondrial	CORUM Protein Complexes	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84261
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52835
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24855
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22434
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TIE1_knockdown_107_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.77317
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.04255
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13341
GSE239844_11_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIX5	ENCODE Transcription Factor Targets	1.0	null
Aerobic respiration and respiratory electron transport	Reactome Pathways 2024	1.0	null
CDC7_knockdown_109_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.7604
SW-620 cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.25962
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27628
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98469
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26285
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360752
PMC7935918-41598_2021_84338_MOESM1_ESM.xlsx-ST12-Unnamed_0_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L363	CCLE Cell Line Gene Expression Profiles	1.0	1.91274
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MH-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.063264
Corpus striatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
BATF	ENCODE Transcription Factor Targets	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22477
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6238
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123836_1_v_0_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mitochondrial inner membrane	GO Cellular Component Annotations 2023	1.0	null
Vagina	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.712986
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09789
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Necrotizing Encephalopathy, Infantile Subacute, Of Leigh	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824314
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10522
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61907
7408_ROCK1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.948235
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04824
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71998
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927072
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78123
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61606
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2354
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13816
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25883
WM88	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47129
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934928
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0534
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-TFAP2C_TFAP2C	Rummagene Transcription Factor Associations 2026	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985193
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8156
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965513
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
DE-28-XP50_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238421
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092688
PMC7657662__F2	PFOCR Pathway Figure Associations 2024	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31072
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3693
Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.357367
E2F1	ChEA Transcription Factor Targets	1.0	null
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137914_4_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60499
TAF7	ENCODE Transcription Factor Targets	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCoV-EMC2012_0Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.24104
MDM2	Hub Proteins Protein-Protein Interactions	1.0	null
PMC4030113__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10303
PMC11630641-mmc8.xlsx-Human_1000cell_NOT_identified-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54112
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926359
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286798
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7509
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16663
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09543
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE137653_4_v_0_siglecf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1775
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14251
KDM1A	ENCODE Transcription Factor Targets	1.0	null
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54508
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26705
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56836
Mitochondrial complex I assembly model OXPHOS system	WikiPathways Pathways 2024	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5026
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DC-08-CM08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242377
optic atrophy	HPO Gene-Disease Associations	1.0	null
VAMP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35341
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43858
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-3.3565
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00912
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_KD_GDS3788_488_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82527
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17008
ldr8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95582
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.852561
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29439
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19505326-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09263
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12845
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831113
RFX5	ENCODE Transcription Factor Targets	1.0	null
Right atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.003
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
electron transport chain	GO Biological Process Annotations 2015	1.0	null
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3742
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Anemia	DisGeNET Gene-Disease Associations	1.0	null
Ascariasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Complex I biogenesis	Reactome Pathways 2024	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50016
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38927
GSE206226_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK8_knockdown_129_GSE30816	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.34704
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947388
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A560-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85311
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34978
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
decreased body weight	HPO Gene-Disease Associations	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21944
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8568
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.439142
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3036
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9565
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24649
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212783
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.928188
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837815
Endocrine pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.255
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55386
PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.53136
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16931
Lung adenocarcinoma_LUAD_TCGA-49-4507-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63293
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30945
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_UP_AA_UP-AA_UP_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
UACC257	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73279
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41597
estradiol_homo sapiens_gpl1225_gse1486	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
muscle fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354826
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06155
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27223
Respiratory chain complex I (holoenzyme), mitochondrial	CORUM Protein Complexes	1.0	null
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.10665
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26717
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25588
PMC11061611-cd-23-0857_table_s4_suppst4.xlsx-T_F1-pT17_FU1_shared_S100_ZNF80	Rummagene Transcription Factor Associations 2026	1.0	null
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10187
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.36498
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
yap1_18413746_mcf10a_gof_human_gpl570_gds3220	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.08983
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19278
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58129
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49193
NDUFS5	Pathway Commons Protein-Protein Interactions	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.72653
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4651_KO_Tip55_SRP134924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.0
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.59996
SP2509	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.04
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99185
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24611
NR2F2	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	1.0	3.14547
PPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31549
Mitochondrial crista	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.103
respiratory chain complex I	GO Cellular Component Annotations 2023	1.0	null
Optic Atrophy	DisGeNET Gene-Disease Associations	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.476753
generation of precursor metabolites and energy	GO Biological Process Annotations 2015	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Death	CTD Gene-Disease Associations	1.0	1.26732
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30626
Mesothelioma_MESO_TCGA-LK-A4O0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149139_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.384
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dendritic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.569
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.83351
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
MJ	DepMap CRISPR Gene Dependency	1.0	3.45195
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
PMC8385445__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.664259
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.27715
BE-17-CS60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281445
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.745765
HCC38	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.50647
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
Oligodendroglioma_CNS - Brain (MMHCC)_GSE2223	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.72622
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
onset	HPO Gene-Disease Associations	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.215063
PMC4398389__F1	PFOCR Pathway Figure Associations 2024	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045909
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.15892
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864628
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.38008
GSE195582_0_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30572
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
20003503-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-7173-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
HF-36-FK93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241449
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86653
ZNF768	Pathway Commons Protein-Protein Interactions	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059354
A549_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136526
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915381
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.936818
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
SALE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85984
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9255
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19278
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979123
GSE224479_0_v_1_ino80_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962073
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.55789
Perturb_5861_KD_H3f3a_SRP133189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.51015
IRAK1_knockdown_115_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.21322
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300967
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50656
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16351
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298883
MCF7_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137124
IRF4	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
heart_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.48054
Perturb_16532_KO_Cdk19_SRP351257	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.384
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.45523
TCF12	ENCODE Transcription Factor Targets	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42142
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05249
Nonalcoholic fatty liver disease	WikiPathways Pathways 2024	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.946744
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.99832
ovary	HPA Tissue Protein Expression Profiles	-1.0	-2.23134
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01564
ECC10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94993
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.444246
Diabetic cardiomyopathy	KEGG Pathways 2026	1.0	null
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844417
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5886-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	2.5575
PMC12420540-44154_2025_254_MOESM1_ESM.xlsx-supplementary_S7-FST_PI_XPCLR_TGB_VS_ZSG_gene_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
U-698-M	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.87707
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29347
proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.698
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4299
5927_OGDH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.634412
AA-45-BL29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331356
PMC11551338-pnas.2411189121.sd01.xlsx-VDR-Unnamed_0_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898858
cellular process	GO Biological Process Annotations 2015	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49193
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.800833
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14067
dysarthria	HPO Gene-Disease Associations	1.0	null
CHLA57	DepMap CRISPR Gene Dependency	1.0	3.86806
GSE180641_0_v_1_zfp503_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0886
PMC6643872__F2	PFOCR Pathway Figure Associations 2023	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ataxia	HPO Gene-Disease Associations	1.0	null
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06743
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.708369
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC59	DepMap CRISPR Gene Dependency	1.0	2.40572
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892967
PAX5	ENCODE Transcription Factor Targets	1.0	null
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8529
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29313
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19639
GSE184884_7_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.384
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33509
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.6278
abnormality of the abdominal organs	HPO Gene-Disease Associations	1.0	null
AF-12-IW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224312
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2981-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBFB	MSigDB Cancer Gene Co-expression Modules	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971801
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.965796
MCF7_Sirtinol_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180565
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35808
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LC1F	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0441
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35679
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42748
SMC3	ENCODE Transcription Factor Targets	1.0	null
1872_CRIM1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.513682
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98086
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46984
Ptosis	DisGeNET Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877101
abnormality of the musculature	HPO Gene-Disease Associations	1.0	null
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44975
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15877
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0321
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12727
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.365
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58142
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE252857_2_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13445
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
Oxidoreductase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826005
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
r4 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10393
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040841
PMC7000220-elife-50163-fig3-data1.xlsx-genes_SOM_xls-gene_symbol_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
7453_RPL26_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.518489
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42763
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10551
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.783323
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.34643
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10187
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43261
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826649
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_CUDC-101_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147685
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.508041
fh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
failure to thrive	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A624-01A-22R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8423
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149264,GSE149267_4_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.3133
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11924
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978425
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5508
PMC5342737-oncotarget-07-75235-s008.xls-match_19_10_2015_heartliver-Supplementary_Table_7_MYC_interacting_genes_that_are_significantly_induced_or_repressed_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10916
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.14873
GSE88819_11_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.820727
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70487
abnormality of the liver	HPO Gene-Disease Associations	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055175
hsa-miR-4790-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12888
abnormality of the optic disc	HPO Gene-Disease Associations	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866836
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
Posterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19977
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849212
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06704
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L33	DepMap CRISPR Gene Dependency	1.0	3.68907
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.339426
10023_ZC3H18_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.665043
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23119
PMC4090731-bjc2014262x1.xls-Sheet1-CaSig-HSF1_Positive_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
global developmental delay	HPO Gene-Disease Associations	1.0	null
Thermogenesis	KEGG Pathways 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00458
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pioglitazone_rattus norvegicus_gpl341_skeletal muscle_gds3850	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948474
abnormality of coordination	HPO Gene-Disease Associations	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22606
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
substance dependence	GWASdb SNP-Disease Associations	1.0	0.217326
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24925
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.43977
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47626
H3K23ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2BK15ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE97	CCLE Cell Line Gene Expression Profiles	1.0	2.00816
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3359
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.28
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278988
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.51573
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845223
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02709
MEF2A-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Leukoencephalopathy with vanishing white matter	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8928_TIMMDC1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.515219
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83289
Respiratory chain complex IV	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.831
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20254
Cyclin E2-CDK2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88018
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormal hair quantity	HPO Gene-Disease Associations	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078556
B-CPAP	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.89992
Thalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0261
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19743
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06069
mitochondrial respiratory chain complex i	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
muscular hypotonia	HPO Gene-Disease Associations	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68574
PDGFRA_knockdown_117_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.64669
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
gill	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.330094
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3664
bladder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.888586
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1476
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2339_DPCD_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.573458
mitochondrial membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.6905
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824458
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.51287
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8571
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21648
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03225
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92908
TAF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203-2004(H5N1)_12Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.1654
ubiquinone biosynthesis	KEGG Pathways	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46059
Apnea	DisGeNET Gene-Phenotype Associations	1.0	null
A549_WP1066_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142874
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86416
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27063
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU61_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.01806
HCT15	DepMap CRISPR Gene Dependency	1.0	6.03718
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4386
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC11949941-DataSheet1.pdf-12-ZNF175_ZNF175	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04354
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.202684
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.66203
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
6152_PDCD11_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.656812
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.865191
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0793
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28887
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Medulla oblongata	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.258
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65364
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6602
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9174_TOP1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.01642
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
GSE205316,GSE205317_2_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
fluoxetine_mus musculus_gpl1261_gse35765	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67168
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6194
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Upregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.99811
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.480739
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.129437
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02702
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0331
Mycolate outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
GSE211866_2_v_1_usp11_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
t55-gastrocnemius_male_1w	MoTrPAC Rat Endurance Exercise Training	1.0	1.32664
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939416
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272786
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Oxoglutarate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.275
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18635
CTCF	ENCODE Transcription Factor Targets	1.0	null
zinc acetate_homo sapiens_gds1617	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NDUFA2	Pathway Commons Protein-Protein Interactions	1.0	null
NR3C1	ChEA Transcription Factor Targets	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11306
NFATC1	ENCODE Transcription Factor Targets	1.0	null
5748_NOP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.613455
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88329
CALR_KO_GDS3680_149_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55539
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23678
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02411
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.274045
proton-transporting two-sector ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.692
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebral peduncle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.247
GTEX-PWOO-0626-SM-48TZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824191
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW-626 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
decidua	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.231206
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11126
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05248
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.973308
A549_CEP-33779_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125999
THAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15947
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16777_KO_Utx/Jmjd3_SRP339500	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.73329
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5979
NB69	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.86622
A549_BMS-536924_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165554
response to oxidative stress	GO Biological Process Annotations 2015	1.0	null
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.074225
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24214
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0206
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46122
Leber congenital amaurosis_Retina_GSE3249	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-3.38904
TBP	ENCODE Transcription Factor Targets	1.0	null
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HPAFII	CCLE Cell Line Gene CNV Profiles	1.0	2.11449
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45159
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36733
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
Adrenal gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10393
1941_CTPS1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.628635
MEF2A-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960931
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC11079006-41467_2024_48118_MOESM7_ESM.xlsx-ZNF274_OE_vs_EGFP_CTR_DE-gene_ZNF274	Rummagene Transcription Factor Associations 2026	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.67891
Cardiac Failure_Myocardial tissue_GSE1988	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.36311
AC-92-HS43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308032
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48389
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63769
HD-22-GO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358604
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.55578
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr12_94997907_C_T_b38	GTEx eQTL 2025	1.0	1.21686
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.264
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.931857
CCC5	DepMap CRISPR Gene Dependency	1.0	4.46201
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.99795
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11801
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rabies CVS-11_7day-Brain_22116324_GSE30577	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73291
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CFPAC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47296
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
ZFX	ChEA Transcription Factor Targets	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986207
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953672
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.0815
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61272
PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_SIX5-gene_SIX5	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of muscle physiology	HPO Gene-Disease Associations	1.0	null
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08277
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00324
creb1_22108299_heart_left_ventricle_lof_mouse_gpl1261_gds3660	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.695665
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
response to stress	GO Biological Process Annotations 2015	1.0	null
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.265381
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04098
SURF1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13816
PAC-1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.92
GSE138945,GSE138947_0_v_1_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.17952
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	Reactome Pathways 2014	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13797
horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61699
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876716
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z1-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.510251
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-T1-A6J8-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0327	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38113
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9526
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45101
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal pattern of respiration	HPO Gene-Disease Associations	1.0	null
heart	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.31267
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.65916
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.518623
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057663
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HO-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5705
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052729
seizures	HPO Gene-Disease Associations	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858441
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bronchial epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.618
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Huntington disease	KEGG Pathways 2026	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50658
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49193
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1329
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80851
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468436
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15591
469_ARHGAP4_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.640352
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.1189
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.883059
A-VN-1203-2004(H5N1)_Day1-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.60286
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37919
P3HR1	CCLE Cell Line Gene CNV Profiles	1.0	1.4916
NCIH1915	CCLE Cell Line Gene Expression Profiles	1.0	2.18179
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.743565
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23911
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28795
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42767
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19743
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2583
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2746
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.38866
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6141
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17696
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42567
proton motive force-driven mitochondrial ATP synthesis	GO Biological Process Annotations 2023	1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00885
PML	ENCODE Transcription Factor Targets	1.0	null
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40559
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
Prefrontal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.433
oxidoreductase activity, acting on nad(p)h	GO Molecular Function Annotations 2015	1.0	null
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07752
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75059
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887076
PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913309
ATP5B	Pathway Commons Protein-Protein Interactions	1.0	null
NR3C1-23031785-PC12-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
KLF1	ChEA Transcription Factor Targets	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040903
Brachial plexus neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
Left ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.117
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70738
increased csf lactate	HPO Gene-Disease Associations	1.0	null
pc3	HPA Cell Line Gene Expression Profiles	1.0	2.0087
GSE217156_2_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5699_NKX6-1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.511498
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LPS6	DepMap CRISPR Gene Dependency	1.0	5.13288
Perturb_10679_KD|Mut_Cux1|Nras_SRP292900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.69648
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4043
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.726446
17676974-TableS2	GeneSigDB Published Gene Signatures	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14267
TIM23 mitochondrial import inner membrane translocase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.08376
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993512
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Left atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.693
MIB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_II-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
Cingulate gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.28
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39276
GSE128333_4_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14165
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U7-06A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.23311
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	1.0	1.78166
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39399
ATP synthesis coupled electron transport	GO Biological Process Annotations 2025	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.78367
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08163
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
t56-vastus-lateralis_female_4w	MoTrPAC Rat Endurance Exercise Training	1.0	1.96908
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
proton motive force-driven ATP synthesis	GO Biological Process Annotations 2023	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03722
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333914
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.238478
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31213
respiratory insufficiency	HPO Gene-Disease Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00841
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDH4-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062113
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.9211
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
431_AQR_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.528569
SAP30	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21121
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51113
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28401
SARS-BatSRBD_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.15121
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08422
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06743
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.10211
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-92-JL46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433607
GSE254848_4_v_13_ptges_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.31658
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85405
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06414
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17949
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-A6W5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844803
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.440131
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.76577
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Organellar ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.711
NF-21-HQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218625
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06704
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.848476
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25526
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
A549_PJ34_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143085
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42807
NARP syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
A549_PHA-680632_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123958
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4133-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.417
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
functional respiratory abnormality	HPO Gene-Disease Associations	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0681
HGC27	DepMap CRISPR Gene Dependency	1.0	3.55427
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00324
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IE-80-DC24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212298
Transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65371
Leigh syndrome due to mitochondrial complex I deficiency	ClinVar Gene-Phenotype Associations	1.0	null
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.089983
SKMEL19	DepMap CRISPR Gene Dependency	1.0	2.03036
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41115
PMC8101445-mbc-32-475-s003.xlsx-HEK_Tim22_KD-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parenchyma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.336
organelle part	GO Cellular Component Annotations 2015	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_3_TurboID_1hr_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rosiglitazone_homo sapiens_gpl570_gds2453	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
16651414-Supp2	GeneSigDB Published Gene Signatures	1.0	null
Mucolipidosis II alpha/beta	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15577
ABL1_knockdown_100_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.83683
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19825
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60076
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10388
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-UT-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.47149
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54302
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994948
CTCF_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.392211
IMR32	DepMap CRISPR Gene Dependency	1.0	3.97326
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958799
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092587
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22267
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052734
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06824
PMC8101445-mbc-32-475-s003.xlsx-HEK_Tim29_KD-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41718
NDUFA4	Pathway Commons Protein-Protein Interactions	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.629743
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059493
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861877
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.914689
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of the respiratory system	HPO Gene-Disease Associations	1.0	null
GSE126463_1_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
16872506-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
t56-vastus-lateralis_female_8w	MoTrPAC Rat Endurance Exercise Training	1.0	2.02262
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
oxidoreductase complex	GO Cellular Component Annotations 2015	1.0	null
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9575
PMC7657662__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11664
respiratory chain complex i	GO Cellular Component Annotations 2015	1.0	null
Cerebral arterial disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937011
ZNF506	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2265
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Generalized dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.432891
NRF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5044-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073563
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17061
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10531
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070703
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02287
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879058
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853509
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01228
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21721
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917002
ATP synthesis coupled electron transport	GO Biological Process Annotations 2023	1.0	null
TAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15409
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.848994
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09288
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65602
Non-alcoholic fatty liver disease	KEGG Pathways 2026	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902812
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901699
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.181164
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9835
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58224
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.293866
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43857
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.11599
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.045
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.316334
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070922
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-5126-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054549
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21454
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6879-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83409
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_0_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.87772
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.78557
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08425
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1359
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aerobic respiration	GO Biological Process Annotations 2023	1.0	null
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11801
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845373
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2792
Amyotrophic lateral sclerosis	KEGG Pathways 2026	1.0	null
TERT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15615
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.430109
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.425889
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87548
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15877
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
succinate-CoA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nadh dehydrogenase (ubiquinone) activity	GO Molecular Function Annotations 2015	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26329
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26841
Medial geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30065
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
AP2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39062
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880885
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.735725
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
NCIH196	CCLE Cell Line Gene CNV Profiles	1.0	2.49503
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71545
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12881
GSE202434,GSE202438_6_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48017
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10393
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99203
Cybrid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852033
Lung squamous cell carcinoma_LUSC_TCGA-85-8354-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15408
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68556
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.760606
nystagmus	HPO Gene-Disease Associations	1.0	null
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89535
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0778
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.947421
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39399
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82388
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
G-292-Clone-A141B1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.59665
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886526
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
CHID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55783
Delayed Ability To Walk	DisGeNET Gene-Phenotype Associations	1.0	null
mrc9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
PMC6643872__F2	PFOCR Pathway Figure Associations 2024	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27651
Subiculum, ventral part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43261
Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCDHB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00759
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
6071_PARK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.734193
GSE253041_3_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.361
TPT1	MSigDB Cancer Gene Co-expression Modules	1.0	null
AF-01-FE42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394574
3-methylglutaconic aciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.26285
KM12	CCLE Cell Line Gene CNV Profiles	1.0	1.56678
MYBL2	ENCODE Transcription Factor Targets	1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496092
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
placenta disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.467684
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
proton motive force-driven ATP synthesis	GO Biological Process Annotations 2025	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17226_KO_lincBrn1b_SRP028547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47089
non-hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.111087
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VK-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841592
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11627
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32277
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE3583	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52117
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01254
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21461
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.578
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.98181
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80296
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300557
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Disease of metabolism	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
MHHCALL3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.30044
HDAC1	ENCODE Transcription Factor Targets	1.0	null
KE97	CCLE Cell Line Gene CNV Profiles	1.0	1.4529
PMC10679653-mmc3.xlsx-ISL1_KO_Markers-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0068
Electron transport chain OXPHOS system in mitochondria	WikiPathways Pathways 2024	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81884
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215086_3_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58142
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cellular respiration	GO Biological Process Annotations 2025	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99496
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311996
GTF2B	ENCODE Transcription Factor Targets	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08888
AA-46-GL76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238143
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-33-4583-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A656-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leigh disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.31581
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.618
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27097
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972393
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-3606	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subthalamic nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.197
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04464
Prostate adenocarcinoma_PRAD_TCGA-M7-A723-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARMCX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18784
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.901432
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Striatum dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05569
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78249
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26685
NPM1	MSigDB Cancer Gene Co-expression Modules	1.0	null
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61033
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5898
SARS-BatSRBD_60Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.92935
H3K36me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.36447
MDM2	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00627
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10393
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
MONOMAC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89594
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17889
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50149
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.378579
RO82-W-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.82684
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62874
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898004
NR3C1-23031785-PC12-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE198971_0_v_2_ncor2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04391
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22997
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06841
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.99147
PLK3_knockdown_121_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.46576
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23376
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54756
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.71345
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.57289
ophthalmoparesis	HPO Gene-Disease Associations	1.0	null
GSE168797_4_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214823,GSE214824_5_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHHNB11	CCLE Cell Line Gene Expression Profiles	-1.0	-2.31527
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85311
GSE211128_9_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52113
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02733
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20758
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10937
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.63095
cns demyelination	HPO Gene-Disease Associations	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85311
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.136
Mitochondrial complex I deficiency	ClinVar Gene-Phenotype Associations 2025	1.0	null
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S01_LF_C1_3h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12652
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62969
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12826982-mmc5.xlsx-Table_S4-Supplementary_Table_S4_Differentially_Bound_Down-regulated_Peak-Related_Genes_in_Flag-SOX3-HSV-1_vs_Flag-SOX3-Mock_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
growth abnormality	HPO Gene-Disease Associations	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
neurodevelopmental delay	HPO Gene-Disease Associations	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908835
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.452928
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93703
Idiopathic scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
iron-sulfur cluster assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12344
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.06345
Lymphoblastic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.369
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.07732
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19632
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09203
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0842
GSE221955_3_v_2_igfbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02903
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2746
Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38073
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886584
K562_Tie2 kinase inhibitor_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169904
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CHD1-19587682-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.938676
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.46125
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ophthalmoplegia	HPO Gene-Disease Associations	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54753
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.491291
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.33133
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15434
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34193
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
TE-03 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hi-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Myocardial Infarction_Myocardial tissue_GSE4105	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.54593
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02457
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U178	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7244
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01173
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.922899
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
B-lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.753
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373462
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Scoliosis, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00197
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25605
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hypertonia	HPO Gene-Disease Associations	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE99112_0_v_1_upf3b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GF-35-IT27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301048
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33672
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.586
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09016
PMC12234789-41467_2025_61560_MOESM3_ESM.xlsx-Supplementary_data_1-Only_YY1_IP-MS_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebrovascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1386
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Strabismus	DisGeNET Gene-Disease Associations	1.0	null
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.896742
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6573_KO_Gls/Mpc2_SRP338093	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.44139
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
Myocardial infarction	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.85
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860062
Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193999,GSE194000_4_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.430647
5216_MRPL34_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.516112
GSE229698_1_v_2_traf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1782
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06743
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67469
Respiratory chain complex II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.666
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.123221
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Intracranial arterial disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
AKT1_knockdown_123_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.77372
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29843
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278664
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965195
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.77238
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38188
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995881
PR8(H1N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.83031
catalytic complex	GO Cellular Component Annotations 2015	1.0	null
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994098
mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64301
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207914_1_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366094
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50079
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218365
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56676
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SLC26A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1302
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16207381-Table1Sa	GeneSigDB Published Gene Signatures	1.0	null
MAP2K1_knockdown_105_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.36534
respiratory chain complex i	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68178
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6868
cytochrome-c oxidase deficiency disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
MB-49-LL22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342316
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72718
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974565
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21119
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.896894
Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Leber hereditary optic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.852
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21221
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	1.0	3.63711
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56513
abnormality of the optic nerve	HPO Gene-Disease Associations	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.927666
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374418
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936201
oxidoreductase complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.009517
dystonia	HPO Gene-Disease Associations	1.0	null
GSE138024_2_v_3_rgs4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Ubiquinone-1	HMDB Metabolites of Enzymes	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34947
Dehydration_Hypothalamus_GSE3110	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.01814
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38437
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Respiratory epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.618
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02552
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1501
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.0373
Retinal arterial tortuosity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
Ritscher-Schinzel syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
b82	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.927447
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263669
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0826-SM-2HML4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40546
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
medial part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14165
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2778-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.09933
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42875
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2632
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03501
2367_DPY30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.526477
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61E-01A-22R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7521-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.864646
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.49131
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
A549_Navitoclax_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112504
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980622
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65843
Pavement epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
PMC6345883-41598_2018_37397_MOESM10_ESM.xlsx-AR_D0_VS_D14__TRANS-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20604
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12081
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15408
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_CHD1_19587682	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058165
NCI-H1703 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
Medulla, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02061
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27513
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831113
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59208
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JVM3	CCLE Cell Line Gene CNV Profiles	1.0	1.65323
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56357
NDUFV2	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lymphoblastoid cell line	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	0.989464
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91357
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.54366
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846104
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01737
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348148
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22728
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.102178
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43924
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10868
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6194
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05081
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.756557
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12085
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24939
NCIH510	DepMap CRISPR Gene Dependency	1.0	2.06366
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12353
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40593
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A620-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.805
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mood Swings	DisGeNET Gene-Disease Associations	1.0	null
PC-68-DU31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349532
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847257
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66725
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13868
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Gametophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.999261
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43579
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901829
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
behavioral abnormality	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.847736
SNU81	DepMap CRISPR Gene Dependency	1.0	3.01018
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CAL51	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37478
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE190384,GSE190386_3_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2133
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
B-lymphoblastoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.753
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917882
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877836
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10359
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96121
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
GSE143643,GSE143644_2_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23803
t55-gastrocnemius_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.64131
Translation initiation ternary complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.857
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74763
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5122
GM2 gangliosidosis, AB variant	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0139
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenotypic variability	HPO Gene-Disease Associations	1.0	null
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22301
GSE87299_2_v_3_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61412
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.19052
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2746
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50104
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01283
envelope	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MKN-74 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
LN215	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73489
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SM-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44195
orbital cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.38472
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828962
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51335
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.484376
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SH4_SKIN	CCLE Cell Line Proteomics	1.0	5.74952
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
16651409-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06239
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paratyphoid fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	3.6302
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20484
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.940787
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75C-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.877234
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.74
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VDR	ChEA Transcription Factor Targets	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.902721
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
endocervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.872749
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H2-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
mRNA_TCF3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394118
JC-02-ZR15_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220303
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3729
ZEB1	ENCODE Transcription Factor Targets	1.0	null
NADH dehydrogenase (quinone) activity	GO Molecular Function Annotations 2023	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Decreased Activity Of Mitochondrial Respiratory Chain	DisGeNET Gene-Phenotype Associations	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043897
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64301
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAD	HMDB Metabolites of Enzymes	1.0	null
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915037
EP300	ENCODE Transcription Factor Targets	1.0	null
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
MOLP2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47172
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86416
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Respiratory chain complex I	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15265
melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.505739
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.463404
CAPAN-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
UACC257	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50134
Hereditary spastic paraplegia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
FOXP2	ENCODE Transcription Factor Targets	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0856
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4617-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oviductal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
A549_Tucidinostat_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124583
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MI-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S2-HSF1_CanSig_Genes-HSF1-CanSig_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Generalized Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
BECN1	MSigDB Cancer Gene Co-expression Modules	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.934039
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.754
Intracranial aneurysm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22038
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6004
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5878
EBF1	ENCODE Transcription Factor Targets	1.0	null
TCCPAN2_PANCREAS	CCLE Cell Line Proteomics	1.0	4.18836
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15852
cd8.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1843
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908041
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04741
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27282
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.679631
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.452068
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3272
lactic acidosis	HPO Gene-Disease Associations	1.0	null
GSE87299_1_v_0_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUIT2_PANCREAS	CCLE Cell Line Proteomics	1.0	2.19478
vincristine_homo sapiens_gpl570_gse7556	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hydrocortisone_homo sapiens_keloid scar_gds3071	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4975
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.763
Perturb_11686_KD_RB1_SRP158041	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
UACC893	DepMap CRISPR Gene Dependency	1.0	4.34015
GSE202434,GSE202438_3_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6194
NDUFA13	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HARA	CCLE Cell Line Gene Expression Profiles	1.0	1.52043
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917258
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3M1-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HARA	CCLE Cell Line Gene CNV Profiles	1.0	1.40353
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187239
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.42115
protein complex	GO Cellular Component Annotations 2015	1.0	null
heart	GTEx Tissue Gene Expression Profiles	1.0	2.17099
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE253056_0_v_1_erythropoietin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154081_1_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
XD-50-BD50_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236481
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32535
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC11093744-41592_2024_2172_MOESM3_ESM.xlsx-ELP-genes_NR5A1	Rummagene Transcription Factor Associations 2026	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069638
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PBMC cell line	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	0.997178
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0793
EZH2	ENCODE Transcription Factor Targets	1.0	null
Nonpigmented ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S7-Table_S7_Top_500_differentially_modified_gene_bodies_between_MM_and_its_precursors_in_AA_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
Respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.309
t56-vastus-lateralis_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.42783
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4079
cell part	GO Cellular Component Annotations 2015	1.0	null
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.6917
inner SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26209
mitochondrial metabolism disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09503
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.869964
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7916
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22873
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_RG108_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133278
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03995
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.485119
Leigh syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20582
catalytic complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.003079
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1244
pparg_21068720_macrophage_c57bl6_lof_mouse_gpl1261_gds4370	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.74056
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hepatitis A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrial inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Focal T2 Hyperintense Basal Ganglia Lesion	DisGeNET Gene-Phenotype Associations	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of the cerebrospinal fluid	HPO Gene-Disease Associations	1.0	null
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36305
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2179
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63769
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.978642
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05677
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11565
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-LY7	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.48379
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96393
NDUFA10	Pathway Commons Protein-Protein Interactions	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5518
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.31689
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7409
Transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.038
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.955326
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.981029
colon_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.989518
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC6345883-41598_2018_37397_MOESM10_ESM.xlsx-AR_D0_VS_D7_W_B29__TRANS-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14165
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268794
Epithalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.403
PMC10721014-pone.0295542.s010.xlsx-Table_S9-Table_S9_Spearman_s_correlation_between_the_expression_levels_of_ESRRA_and_OXPHOS_subunits_genes_ESRRA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8691
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07987
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50065
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00917
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53342
EB-3	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.53415
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309465
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980252
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5366
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t59-kidney_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.96258
7834_SF3A3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.558099
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137144_3_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949308
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56743
U2904	DepMap CRISPR Gene Dependency	1.0	2.09588
oxidoreduction-driven active transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.829181
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69744
SPI1	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H0-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6319
A-Vietnam-1203-2004(H5N1)_2day-wtC57BL-6J_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.72312
female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.088807
Right_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.64665
MRPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56026
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54468
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15279
Barth syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
Acquired Immunodeficiency Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2686
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cyclosporine_homo sapiens_gpl570_gse15935	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31159
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5738
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22108
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22025
Thymus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.381
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.998049
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090383
SW 527	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.05839
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846943
Caudate nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.221
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856046
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078296
all	HPO Gene-Disease Associations	1.0	null
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
childhood-onset dystonia with optic atrophy and basal ganglia abnormalities	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09574
MDA-MB-361	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16495
YAMATO	DepMap CRISPR Gene Dependency	1.0	4.25462
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10393
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18344
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852012
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950861
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.645416
NZOV9	DepMap CRISPR Gene Dependency	1.0	4.06171
Mitochondrial respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.075
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
membrane part	GO Cellular Component Annotations 2015	1.0	null
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.950208
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
143B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44402
nfe2l2_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.474081
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03856
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
XC-81-LR46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270226
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.869923
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5871-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
Dysarthria	DisGeNET Gene-Disease Associations	1.0	null
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836438
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Perturb_10788_KO_Shp_SRP220815	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.15574
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4	ChEA Transcription Factor Targets	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913309
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39399
PAX5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2366
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9259
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
KIT_activemutant_55_GSE17743	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.99203
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23451
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.488644
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCoV-EMC2012_7Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.15326
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63928
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.37986
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22375
GSE227634,GSE228381_0_v_7_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225176
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44321
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220017
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
respiratory failure	HPO Gene-Disease Associations	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.946519
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.0675
Lung squamous cell carcinoma_LUSC_TCGA-56-8304-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.023356
intellectual disability	HPO Gene-Disease Associations	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.911
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22995
PMC3470785-NIHMS377161-supplement-12.pdf-481-ZNF395_ZNF395	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6453
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.572312
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87176
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	1.0	1.36348
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.215063
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981816
ERVMER34-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58839
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.03604
single-organism process	GO Biological Process Annotations 2015	1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.018
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7657
t30-blood-rna_male_2w	MoTrPAC Rat Endurance Exercise Training	1.0	1.41978
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870781
deferasirox_homo sapiens_gpl570_gds3558	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GSE168797_4_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Oxidative phosphorylation	KEGG Pathways 2026	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068821
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08009
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.096
GATA3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.081
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864548
7501_RPS13_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.604049
PMC10800016-table_s5_20230913_ddad186.xlsx-FvsC_-_DUX4_II-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1257	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.972176
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08508
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.212271
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bj	HPA Cell Line Gene Expression Profiles	-1.0	-0.983143
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.12478
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00089
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03463
MEC2	CCLE Cell Line Gene Expression Profiles	1.0	1.86011
7751_SEC61A1_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.56941
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3501
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67379
QH2	HMDB Metabolites of Enzymes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM160113	DepMap CRISPR Gene Dependency	1.0	4.47904
Lung adenocarcinoma_LUAD_TCGA-44-3398-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12571111-qiaf131_supplementary_data.xlsx-ST3-Supplementary_Table_3_Genes_in_the_two-sample_MR_results_supplementary_table_2_which_pass_an_FDR-P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
abnormality of the cerebellum	HPO Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10612
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18463
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lactic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0465
Axillary bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20666
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Midbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.247
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88732
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Respirasome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BF-94-CQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289216
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14322
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the metencephalon	HPO Gene-Disease Associations	1.0	null
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Organelle inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.095
spindle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.300679
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858363
CE-48-TP40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356674
rosiglitazone_mus musculus_gpl1261_control_gds4036	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206374
Heart ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.117
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TF-77-DW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.944555
Organelle inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134191_3_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BE-66-UB12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221899
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4828
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06039
SUM185PE	DepMap CRISPR Gene Dependency	1.0	4.31925
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.826144
Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9811745-40246_2022_449_MOESM1_ESM.xls-Sheet1-HOXA2_HOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890511
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_EED226_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141591
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17051
abnormality of the posterior segment of the eye	HPO Gene-Disease Associations	1.0	null
GSE206400_1_v_2_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ranolazine_mus musculus_gpl1261_gse25767	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38933
hepatocellular necrosis	HPO Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-DX-A23V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chromosomal aberration frequency (chromosome type)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95967
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-4.45507
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mifepristone_homo sapiens_gpl6947_gse39654	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.69568
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mitochondrial envelope	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NDUFB10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SW156	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05078
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX15	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MICOS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
bone cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.508041
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09874
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	1.0	3.37719
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09856
Hypertrophic Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8903
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.835737
Hyperreflexia	DisGeNET Gene-Phenotype Associations	1.0	null
organelle inner membrane	GO Cellular Component Annotations 2015	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34676
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48836
ATP5C1	Pathway Commons Protein-Protein Interactions	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2315
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89262
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055105
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039599
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.45115
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE171724_4_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.930362
LB373-MEL-D	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.69169
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6301
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A541-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26178
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36
Leigh Syndrome Due To Mitochondrial Complex I Deficiency	DisGeNET Gene-Disease Associations	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.96822
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53303
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84054
PMC11079006-41467_2024_48118_MOESM7_ESM.xlsx-E2F6_OE_vs_EGFP_CTR_DE-gene_E2F6	Rummagene Transcription Factor Associations 2026	1.0	null
nadh dehydrogenase (quinone) activity	GO Molecular Function Annotations 2015	1.0	null
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37132
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
vorinostat_homo sapiens_gpl10558_gse35242	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57412
Blood-cd24 neutrophil	Tabula Sapiens Gene-Cell Associations	1.0	-0.263962
adrenal gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IKBKE_knockdown_97_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.97136
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYNCRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40976
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16753
Mitochondrial respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.712
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12085
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.19312
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.31392
1040_C1ORF131_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.727273
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21607
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.828105
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054831
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190384,GSE190386_1_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23373
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54839
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.512
ZNF384	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12139
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Iniparib_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0107944
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921972
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23402
PMC11585558-41467_2024_54547_MOESM8_ESM.xlsx-TP53_vs_WT_DEG_FFPE-gene_name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SCC9	DepMap CRISPR Gene Dependency	1.0	2.40258
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369408
NDUFS8	Pathway Commons Protein-Protein Interactions	1.0	null
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28763
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP1CC	MSigDB Cancer Gene Co-expression Modules	1.0	null
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48536
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11044
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.700379
Brain Lower Grade Glioma_LGG_TCGA-DH-5141-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14476
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Axillary bud meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47411
KH7	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.07
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858441
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03317
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.885955
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88337
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24764
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.80235
valproic acid_mus musculus_gpl1261_gds3002	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.043476
Pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.475
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.983903
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13572
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06984
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851102
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20177
PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882134
PMC7397849-supp_gad.338681.120_Supplemental_Table_S1.xlsx-S1L_Shared_genes_3way_overlap-Suppl_Table_S1L_Shared_genes_between_YAP1-MAMLD1_YAP1-FAM118B_YAP1-TFE3_in_vitro_human_samples_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45897
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ITK_knockout_241_GSE12465	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52216
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.596729
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OE-31-YC41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215342
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63466
beta-TC3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
GTEX-T5JW-0226-SM-4DM7I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46747
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.440085
MAPK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54586
SETDB1	ENCODE Transcription Factor Targets	1.0	null
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.845097
UACC-812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7145-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Erythroid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.137
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17466
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56094
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGFR_drugactivation_20_GDS2146	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.15181
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15794
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75633
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79217
16207381-Table1Sb	GeneSigDB Published Gene Signatures	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20604
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METFORMIN HYDROCHLORIDE	DGIdb Drug Targets 2026	1.0	0.326741
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mitochondrial inner membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945636
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.23616
HNF1A-26855178-CACO2-HUMAN-COLON-ADENOCARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE155567_1_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23162
organelle inner membrane	GO Cellular Component Annotations 2023	1.0	null
Atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.003
metabolic process	GO Biological Process Annotations 2015	1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041176
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061312
intermediate filament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.227397
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95837
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076171
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.31123
REST	ChEA Transcription Factor Targets	1.0	null
PMC8249453__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
fluoxetine_mus musculus_gpl1261_gse35761	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of the abdomen	HPO Gene-Disease Associations	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24143
EGR1	ENCODE Transcription Factor Targets	1.0	null
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20314
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.885464
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043217
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MM253	DepMap CRISPR Gene Dependency	1.0	4.26153
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10393
TRIM28	ENCODE Transcription Factor Targets	1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.527251
Simple Obesity	DisGeNET Gene-Disease Associations	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.962412
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.545342
NDUFB5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
DECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0608
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Leukemia cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.369
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990493
SRF	ChEA Transcription Factor Targets	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.38097
GSE254848_4_v_3_ptges_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05238
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824808
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872591
17724462-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE139966_5_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.71913
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943701
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921194
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4784386__F4	PFOCR Pathway Figure Associations 2023	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79475
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.906461
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954474
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.841857
Leigh disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.6
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-BCL9-STAT3_targets_DEG_Control-GeneName_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24251
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4776
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SB 525334	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.75
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKPNDW	DepMap CRISPR Gene Dependency	1.0	3.30857
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06351
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55011
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19285
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6771_PRKRIP1_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.500266
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060367
DC-51-WE27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27901
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14709
ME-344	DGIdb Drug Targets 2026	1.0	0.35288
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00278
MFM-223	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.34265
spasticity	HPO Gene-Disease Associations	1.0	null
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24842
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46059
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04874
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59445
SNU1079	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55227
efo21	HPA Cell Line Gene Expression Profiles	-1.0	-1.795
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01705
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.81106
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parkinson disease	KEGG Pathways 2026	1.0	null
GSE151782_2_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.881505
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHUK_knockdown_108_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.41111
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59367
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.94852
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2739
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069493
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	1.28153
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044368
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04162
oxidoreductase activity, acting on nad(p)h, quinone or similar compound as acceptor	GO Molecular Function Annotations 2015	1.0	null
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2854
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08396
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.365
eGFP-NR4A1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04428
LAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63491
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31877
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06281
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22952
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03722
MMGT1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.26247
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERLIN1	Pathway Commons Protein-Protein Interactions	1.0	null
Viral cardiomyopathy_Myocardial tissue_GSE4172	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.01172
BE-16-UV45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409879
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9956
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16232
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.828147
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.824781
Ubiquinone-2	HMDB Metabolites of Enzymes	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0842
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12231
mature t-cell and nk-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.366671
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62232
A549_AG-14361_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143611
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39399
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U343	CCLE Cell Line Gene Expression Profiles	-1.0	-2.33305
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91086
KMOE-2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.49702
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0793
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.934177
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Mitochondrial respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6801
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Increased Serum Lactate	DisGeNET Gene-Phenotype Associations	1.0	null
furan	CTD Gene-Chemical Interactions	1.0	null
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48167
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20604
GTEX-TMMY-0726-SM-33HBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913379
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988076
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9132
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863128
oxidative phosphorylation	GO Biological Process Annotations 2025	1.0	null
PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36889
FAD	HMDB Metabolites of Enzymes	1.0	null
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Globus pallidus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.045
Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893777
STAT1	ENCODE Transcription Factor Targets	1.0	null
GTF2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01604
leigh disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
NDUFB3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30213
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31674
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.61469
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828958
nb4	HPA Cell Line Gene Expression Profiles	1.0	1.15565
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.665625
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Spindle pole centrosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.84
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65737
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.23788
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.567078
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22917
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.065436
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27254
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254526
Sarcoma_SARC_TCGA-DX-A3U5-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06202
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heel bone mineral density x serum urate levels interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.00969
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	InterPro Predicted Protein Domain Annotations	1.0	null
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26239
NCIH446	DepMap CRISPR Gene Dependency	1.0	3.01343
COLO678	CCLE Cell Line Gene Expression Profiles	-1.0	-3.04202
SW900	CCLE Cell Line Gene Expression Profiles	1.0	1.51288
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SH2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17954
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44242
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20333
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17508
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFA6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10983967-media-1.pdf-31-XBP1_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060156
PMC6781638__F4	PFOCR Pathway Figure Associations 2023	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3758
Adrenocortical carcinoma_ACC_TCGA-OR-A5J7-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75605
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33648
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13945
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57793
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Endopeptidase Clp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.063
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.05015
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5353
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57091
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969163
POU2F2	ENCODE Transcription Factor Targets	1.0	null
hearing impairment	HPO Gene-Disease Associations	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
EFO21	CCLE Cell Line Gene Expression Profiles	-1.0	-3.21085
AURKA_knockdown_89_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.8602
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954618
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67A-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38165
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056804
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88691
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21686
DHX58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04638
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.423231
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63779
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6131
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.363
SARS-BatSRBD_60Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.59409
GSE160373_8_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Inherited metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18506
SNCA	Hub Proteins Protein-Protein Interactions	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223177
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71924
VB-89-RG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356433
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59931
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Respiratory electron transport	Reactome Pathways 2014	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37234
BL-41	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.16483
LN443	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16282
Lung squamous cell carcinoma_LUSC_TCGA-85-A512-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-32-IZ10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290588
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079345
U937_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.16932
NCI-H3118	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.60928
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984542
NDUFA11	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199606_5_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77057
reticulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402901
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16942
Respiratory electron transport	Reactome Pathways 2024	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.30936
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26042
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.112
Guanfacine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.52
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01462
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nicotine dependence	GWASdb SNP-Disease Associations	1.0	0.569379
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2891
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Down_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16549
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10078
stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.458373
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3941
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38125
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1853
JVM-2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-5.63993
Eltrombopag	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.49
7,8-Dihydroxyflavone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.69
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04637
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02061
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08539
Acute lymphoblastic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.369
Intrinsic component of mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07814
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SET2	DepMap CRISPR Gene Dependency	1.0	5.559
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13417
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999109
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01812
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948713
Chemical carcinogenesis - reactive oxygen species	KEGG Pathways 2026	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834278
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31708
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S5_Miz-1_KD_gene_exp_chan-Genes_up-regulated_in_Miz-1_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6436-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15408
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ndufa12	GeneRIF Biological Term Annotations	1.0	null
Colorectaladenocarcinoma	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.21465
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-NR3C1_targets_enrichment-Unnamed_5_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32606
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y5-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carbon phosphorus lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5152-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04631
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04452
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPAN1	DepMap CRISPR Gene Dependency	1.0	2.92644
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39399
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05521
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.889
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94313
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.99221
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06273
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29889
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36305
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.611346
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.865055
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02458
Viral hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the glial cells	HPO Gene-Disease Associations	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03746
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06743
forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278955
NCI-H2110	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.59959
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLK1_knockdown_98_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.6484
Hematopoietic cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.369
fluoxetine_mus musculus_gpl1261_gse35763	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XGQ4-2626-SM-4AT6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862991
ZMIZ1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.02038
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
GTEX-R55G-0526-SM-2TC5O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60441
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12751
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5645
PFN1	MSigDB Cancer Gene Co-expression Modules	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.384224
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15232
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02933
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31776
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111756
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00876
Mitochondrial proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
reticular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856144
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43032
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63815
COPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29939
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCIXC	DepMap CRISPR Gene Dependency	1.0	2.11779
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE172146_2_v_1_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875293
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04263
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904591
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NDUFS4	Pathway Commons Protein-Protein Interactions	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.59403
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08087
Leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.369
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dihydrolipoyl dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.352
oxidation-reduction process	GO Biological Process Annotations 2015	1.0	null
MIR221_KD_GDS4054_455_human_MCF7 breast cancer cells (fulvestrant-resistant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
supernumerary	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mitochondrial metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0669
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00876
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49274
AA-79-SX47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220775
hearing abnormality	HPO Gene-Disease Associations	1.0	null
Mitochondrial envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876168
8288_SOX2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.611299
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23306
KDM5B	ENCODE Transcription Factor Targets	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02514
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.08
YB-79-DM48_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262129
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory chain complex I, mitochondrial	CORUM Protein Complexes	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1548
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298165
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.16815
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03062
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.85964
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxidoreductase activity	GO Molecular Function Annotations 2015	1.0	null
Flight muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0855
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47626
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KOPN-8	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.57565
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8455
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04979
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28931
GSE252857_2_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
TWF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10166
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852193
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.10011
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70799
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
disease of metabolism	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Mitochondrial intermembrane space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.39138
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233731
Kearns-Sayre syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878477
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.578167
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.08055
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908835
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
KMRC1_KIDNEY	CCLE Cell Line Proteomics	1.0	3.77844
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29322
HMEL	CCLE Cell Line Gene Expression Profiles	-1.0	-2.50722
3-methylglutaconic aciduria with cataracts, neurologic involvement and neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
Mitochondrial membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.430557
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Blepharoptosis	DisGeNET Gene-Disease Associations	1.0	null
FA-36-VA24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.348084
ATP5H	Pathway Commons Protein-Protein Interactions	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2676
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03169
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.952149
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05374
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859125
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
Nuclear proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.754
ESRRB	ChEA Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.865479
cumulus-oocyte complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
SUZ12	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.28151
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45431
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11137
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14942
CW-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.35149
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20215
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070605
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.35044
gefitinib_homo sapiens_gpl570_gse20854	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Alzheimer disease	KEGG Pathways 2026	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057014
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.915193
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
NUGC-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02219
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-STAT3_target_genes_in_N1-GOPC_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18928
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52399
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFA7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935302
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155567_3_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76707
cytochrome-c oxidase deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.596
Progressive Spastic Paraplegia	DisGeNET Gene-Phenotype Associations	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.46601
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCOR-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889007
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70276
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.38081
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
Hepatitis E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
SR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955569
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21413
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980687
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leigh disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
NDUFB9	Pathway Commons Protein-Protein Interactions	1.0	null
Fibre tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.247
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973304
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61606
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08768
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Placenta praevia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
Intrinsic component of mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.999
Metabolism	Reactome Pathways 2024	1.0	null
abnormality of body weight	HPO Gene-Disease Associations	1.0	null
DB-11-SS01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228477
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01437
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38933
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.33541
PMC12587232-DOM-27-6894-s001.pdf-18-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52738
Hepatic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16386_Mut_Rps2_SRP277547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.37655
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal muscle tone	HPO Gene-Disease Associations	1.0	null
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02514
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75985
The citric acid (TCA) cycle and respiratory electron transport	Reactome Pathways 2014	1.0	null
Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NDUFB8	Pathway Commons Protein-Protein Interactions	1.0	null
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04414
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0132
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	1.0	2.92252
PMC7616765-EMS198548-supplement-Data_S2.xlsx-3_DEG_2D_and_3D-D9_Up_in_2D_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24036
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70954
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.986024
Avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.384
KB-92-MK13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394529
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05097
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PANC0213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46786
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0151
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15852
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056229
SW480	CCLE Cell Line Gene Expression Profiles	1.0	2.43131
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD-16-KY17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432601
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Desipramine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
RCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39938
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900639
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-AA_up_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE201409_1_v_6_coumarin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Optic atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
leigh syndrome due to mitochondrial complex 1 deficiency	OMIM Gene-Disease Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null