association	dataset	threshold value	standardized value
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55685
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48369
NCIH2009	CCLE Cell Line Gene CNV Profiles	1.0	1.81672
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29392
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39675
GPATCH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86556
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.60919
Perturb_7400_KD_AFF3_SRP009568	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.26114
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29223
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840379
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUDHL8	DepMap CRISPR Gene Dependency	1.0	2.66624
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26939
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24426
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62951
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37398
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1348
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60232
FOSL1	ENCODE Transcription Factor Targets	1.0	null
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12769
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952652
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33211
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5063
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIA1_KO_GSE54418_260_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC11328671-jitc-12-4-s003.pdf-281-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
FGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57037
NCIH82	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34844
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SF3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4498
HIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60268
GSE109111_2_v_0_stim1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Perturb_15772_KO_Uxt_SRP240277	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
FBXO48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55953
KP1NL	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14861
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02421
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
erythroleukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469599
Posterior parietal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05097
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25192
FASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17242
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68416
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE189356_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19741
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18719
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29977
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6191
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977882
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7727
D542MG	DepMap CRISPR Gene Dependency	1.0	2.71623
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2903
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06196
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865147
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.86837
amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.155121
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.871064
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.05917
STPG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37937
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BPNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27341
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02588
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858843
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.887672
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29223
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888764
tonsil	HPA Tissue Gene Expression Profiles	-1.0	-0.82741
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.98693
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74877
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07561
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.899776
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7776
U118MG	CCLE Cell Line Gene Expression Profiles	1.0	1.665
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
REST_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972742
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05074
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72382
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987199
MORCPR	CCLE Cell Line Gene CNV Profiles	1.0	1.3742
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.8675
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
Large Cell Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28246
SBC5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38431
GTEX-PSDG-1026-SM-48TCV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848314
PMC12077596-NIHMS2076735-supplement-3.xlsx-ATAC_RNA_NONO_TFE3-WT_up-gene_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7249
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23637
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79037
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961037
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
Hyphal tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.179
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02961
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929339
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06719
isthmic part of the intermediate lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51314
thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.439123
OSGEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43253
pc3	HPA Cell Line Gene Expression Profiles	1.0	2.00239
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62469
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44566
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9476
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77044
YBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23027
MAN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89868
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22247
Nucleus of the lateral lemniscus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11934
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64033
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2064
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921025
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83748
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.8522
ZNF791	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84167
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31177
A1207	CCLE Cell Line Gene Expression Profiles	-1.0	-2.73921
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_10738_KD_Ddx3_SRP324914	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.3274
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57065
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12873
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21361
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864987
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32512
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_14_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.049842
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.247
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35933
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.925206
Differentiated thyroid gland carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83653
CARD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63588
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00391
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10523
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22543
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01767
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03947
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23374
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14386
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55E-1126-SM-48FDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36496
PMC12454923-JEV2-14-e70164-s002.pdf-48-NFKB1_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98569
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42785
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12246
ZNF773	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29087
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12134
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76862
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993719
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30588
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11559
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28541
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03942
OVMIU	DepMap CRISPR Gene Dependency	1.0	8.34905
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36894
GSE89032,GSE89033_0_v_1_sfpq_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANP32E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4171
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.8675
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79729
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5368
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18798
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	0.8675
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25883
SNX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49139
nasopharynx	HPA Tissue Protein Expression Profiles	-1.0	-0.987357
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33381
TRIM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45426
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.74807
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09513
PC14	CCLE Cell Line Gene CNV Profiles	1.0	1.65516
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87872
THAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66462
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83545
Site of polarized growth	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.971
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12423
Chondrosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE165682_2_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02496
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96814
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43895
GSE84922,GSE84924_0_v_3_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04695
G3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33874
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921993
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89691
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66408
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.155121
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6702
CHD7	ENCODE Transcription Factor Targets	1.0	null
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94881
NCIH446	CCLE Cell Line Gene Expression Profiles	1.0	1.5242
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57168
ARID3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860695
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.00497
PRCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53395
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918486
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06168
Perturb_16928_KO_Fam13a_SRP220671	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.52165
DPP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.322
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20066
ARO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842852
HCFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.14239
KLF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13796
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43756
Woronin body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
NKX3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58826
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08825
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3663_KD_RBM26/RBM27_SRP243927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83373
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S117	DepMap CRISPR Gene Dependency	1.0	2.2406
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2945
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17109
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF600	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50583
RNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81902
VEGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4993
ACCS	CCLE Cell Line Gene Mutation Profiles	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070005
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	0.8675
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36834
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85706
H3K27me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06893
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.885758
Split septin rings	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.196
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
CHAGOK1	DepMap CRISPR Gene Dependency	1.0	5.35442
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39165
NIF3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90755
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0982
bone marrow cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.15252
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.908934
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37417
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25718
SNU899	CCLE Cell Line Gene CNV Profiles	-1.0	-2.39204
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916424
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17617
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909846
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0717
H2BC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53031
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211177,GSE211178_0_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995539
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03662
adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.309928
PANC0203	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0074
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45273
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5135_KO_Ythdc1_SRP251747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.48146
HH	CCLE Cell Line Gene Expression Profiles	1.0	1.96967
COLO320	CCLE Cell Line Gene Mutation Profiles	1.0	null
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.943757
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77239
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401765
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867697
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5094
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41681
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88711
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893802
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58887
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09844
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08413
GSE56235_1_v_0_prdm11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Complex laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.558
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76724
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01819
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27859
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9838
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.926162
ion binding	GO Molecular Function Annotations 2015	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCIXC	DepMap CRISPR Gene Dependency	1.0	2.00463
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26269
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19126
FOSL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00103
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15504
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03183
atp binding	GO Molecular Function Annotations 2015	1.0	null
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89861
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44561
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07503
PK45H	CCLE Cell Line Gene CNV Profiles	1.0	2.29936
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34045
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-x_LPS-BMDCs-mouse_kinase_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06697
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5977
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH2030	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5131
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23233
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35807
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.123231
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.82271
RAD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9756
Old mitotic spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3529
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.915222
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4897
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07802
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4585
PPP1R3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52956
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4392
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07033
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58468
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15691
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14884
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33174
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31701
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348148
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74984
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3443
RBBP5	ENCODE Transcription Factor Targets	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0528
tcf12_20154672_cd4pos_cd8pos_thymocytes_thymus_lof_mouse_gpl6246_gse19923	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.745415
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4706
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903383
ESR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65575
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9265
MELHO	DepMap CRISPR Gene Dependency	1.0	2.2953
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1166
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.983808
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49709
TSPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23368
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11208
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57209
papillary thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.198
Perturb_11322_KO_Bmal1_SRP060295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.90311
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11257629-media-3.xls-Dong_et_al_2023-Comparision_of_METTL3_KD_DEG_with_Dong_et_al_GRGs_AR	Rummagene Transcription Factor Associations 2026	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09844
Perturb_8900_KD_SRF_SRP359044	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.49184
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33829
SNU620	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00329
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6111
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42559
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28024
KLK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83768
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MESP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13206
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0386
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48766
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48618
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54227
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7224
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14873
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922229
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24184
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12372
PIH1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81814
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908014
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67597
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
KNS42	CCLE Cell Line Gene Expression Profiles	1.0	2.27042
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3328
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4614
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03611
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00898
EP300_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05411
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.880218
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29911
Prospore contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.11
TE-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01362
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5325
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56723
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
H3K27me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466885
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28648
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.85966
COX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25957
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36999
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8445
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070769
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5497
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69158
Protein kinase, ATP binding site	InterPro Predicted Protein Domain Annotations	1.0	null
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50086
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40065
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.828
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48677
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19508
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955101
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE225647_1_v_3_srsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.987357
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03709
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13258
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
protein phosphorylation	GO Biological Process Annotations 2023	1.0	null
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.48878
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5452392-13058_2017_854_MOESM3_ESM.xlsx-Table_S7-Variants_within_GWAS_blocks_control_MAF_0_01_case_MAF_control_MAF_within_gwas_breast_cancer_regions_deleteious_score_0_5_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904905
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319134
ZNF652	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6609
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52496
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29269
PRODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3307
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59648
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24261
NCIH1703	CCLE Cell Line Gene CNV Profiles	1.0	1.61136
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9202
TRAMP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
ARRDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7842
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20889
thyroid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09341
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5397
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56387
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12904
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1229
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KCNK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5931
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46635
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10148
SAP30	ENCODE Transcription Factor Targets	1.0	null
PMC7064337-elife-51373-supp1.xlsx-SUZ12_targets_shPHF19-List_of_567_genes_marked_by_SUZ12_ChIPseq_iafter_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13003
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RGL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88939
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08862
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87156
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65606
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51671
JUN_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28151
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05062
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41962
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13134_KO_Pnpt1_SRP134850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.2885
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.959785
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40728
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31711
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063498
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16086
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0125
HS294T	DepMap CRISPR Gene Dependency	1.0	11.158
ATP binding	GO Molecular Function Annotations 2025	1.0	null
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06045
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38109
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13361
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0595
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.98944
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83614
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.16768
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.835405
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92764
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858843
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23116
FADU	CCLE Cell Line Gene Mutation Profiles	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058084
non-small cell lung carcinoma	GWASdb SNP-Disease Associations	1.0	0.780437
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96584
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10296
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04692
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8165
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	-1.0	-0.987357
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23263
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0279
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5924
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DE-85-FR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.458823
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30443
LRP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44991
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74635
Perturb_5042_Mut_Adnp_SRP313259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.96721
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10225
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ARHGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37029
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92597
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15027
TE5	CCLE Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20247
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.951503
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1003
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53493
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02672
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880971
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.97402
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13596
Anaplastic thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.423
HS729	CCLE Cell Line Gene Mutation Profiles	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35367
RTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49487
AUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96111
STAT1	ENCODE Transcription Factor Targets	1.0	null
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43342
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral TG part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19697
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174617
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2472
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.81969
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2893_KO_Nfia_SRP077282	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.9256
GOLGA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41229
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21296
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22685
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.209858
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27834
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053382
cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.719015
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45212
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27322
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38151
FOXRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79371
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.922952
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.32333
COL6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34942
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08364
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909822
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.127
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80152
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1521
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC29A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92973
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.945315
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4317
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.693
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95672
Plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.039
ZNF738	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74262
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0375
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
protein modification process	GO Biological Process Annotations 2023	1.0	null
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12597
ZNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33804
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42325
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8773
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
NCIH2110	CCLE Cell Line Gene CNV Profiles	1.0	1.62086
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995315
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00562
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09472
thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.707631
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21621
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975209
T3M10	CCLE Cell Line Gene CNV Profiles	1.0	1.39593
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNPTAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51666
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48834
HPAC	CCLE Cell Line Gene CNV Profiles	1.0	1.38548
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.943
GSE125403_7_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21327
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.089
CHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4215
Actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.368
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	3.03953
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14873
YKG1	CCLE Cell Line Gene Expression Profiles	1.0	1.39997
GTEx Colon 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	16.177
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07817
GLDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74597
cancer	GWASdb SNP-Disease Associations	1.0	0.042087
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
vagina	HPA Tissue Protein Expression Profiles	1.0	0.8675
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971035
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein modification process	GO Biological Process Annotations 2025	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02495
ERCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80505
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0107
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hypodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.959017
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88194
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16995
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0928
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11643
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20839
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43989
STAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16331
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.996293
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31752
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316588
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80486
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23381
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78837
NR1H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57946
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Follicular adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
posteroventral (inferior) parietal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883314
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0514
MERO14	DepMap CRISPR Gene Dependency	1.0	4.81158
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2626
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975648
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887398
Multiple synapse bouton, contacting multiple dendrites	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.84398
THP1	CCLE Cell Line Gene Expression Profiles	1.0	1.47512
hsa-miR-371-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Division septum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898675
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88899
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
Cellular bud neck septin structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.909
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Cleavage apparatus septin structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.909
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18138
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZMAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22907
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17902
EPS8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03443
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95382
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4536
GSE189356_5_v_6_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58624
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-geneID_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99184
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19188
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915985
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HECTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89456
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05144
Magnesium	HMDB Metabolites of Enzymes	1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7071
TTLL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42308
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48982
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955368
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42294
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39991
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84259
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72713
REST_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949526
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37026
MAFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03955
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60467
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899854
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24337
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6468
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49655
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53424
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18174
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00434
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.02144
PSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00797
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12735
SLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60062
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841651
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19567
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25735
FAM83G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12199
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60978
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87973
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25452
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14229_KO_Kdm2b_SRP060647	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.17605
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11342
S100A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30582
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-0.921668
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
Perturb_15978_KO_Tsga8_SRP254760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.42139
PTPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34532
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935766
Perturb_1821_KO_Irf5_SRP233379	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.11972
MBOAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15992
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33347
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30814
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933321
complex laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.803855
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT	CCLE Cell Line Gene Expression Profiles	1.0	1.59476
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.873902
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25895
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
prostate	HPA Tissue Protein Expression Profiles	-1.0	-0.987357
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.881689
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17216
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07882
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052042
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12485
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825017
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7462
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063287
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H357	DepMap CRISPR Gene Dependency	1.0	6.65247
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.96922
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11723
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830568
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993366
SNUC2A	CCLE Cell Line Gene Mutation Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00347
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09907
RFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94713
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
Perturb_14833_KD_Scr_SRP017110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
lateral pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11015
Thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.71
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1888
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-15a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25004
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875169
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21671
mp3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
Perturb_14651_KD_Dis3_SRP297013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.45748
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9179
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3101
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.995687
NFIC	ENCODE Transcription Factor Targets	1.0	null
REST_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94
Olfactory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03497
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40592
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91008
NCIH2286	CCLE Cell Line Gene Mutation Profiles	1.0	null
bewo	HPA Cell Line Gene Expression Profiles	-1.0	-1.12775
SOX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21902
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27949
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAP1L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4165
Symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
KIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98357
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49095
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60605
MPF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.408
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44283
metal ion binding	GO Molecular Function Annotations 2025	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.04947
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08289
GSE142684_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33941
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83371
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EHBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76496
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47478
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47671
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84617
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2333
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18524
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22112
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02644
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4089
NCIH2106	CCLE Cell Line Gene Mutation Profiles	1.0	null
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.05059
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4887
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883497
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03497
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956143
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.981444
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89982
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52595
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21184
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951318
OSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21357
RCHACV	DepMap CRISPR Gene Dependency	1.0	4.65252
ATP6V0A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52663
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.88828
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18627
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2668
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842039
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
KAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83845
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02608
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF354B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55048
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.079163
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832113
PARK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83236
mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.171785
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18407
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28816
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02695
SOX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46864
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3603
FANCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67412
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74203
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16657
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3157
PELI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99235
CORL279	CCLE Cell Line Gene CNV Profiles	1.0	1.95318
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	1.43715
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01005
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02083
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974625
FOS	ENCODE Transcription Factor Targets	1.0	null
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14699
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23136
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08364
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.01244
OE33	CCLE Cell Line Gene Mutation Profiles	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung_3e	HPA Tissue Sample Gene Expression Profiles	1.0	1.29043
ENSG00000170846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69918
anaphase-promoting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.101
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31451
TSPAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06693
T84	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33462
u87	HPA Cell Line Gene Expression Profiles	1.0	1.6346
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33719
ZIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13596
SCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6773
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18407
GSE248858_6_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18527
GSE88819_11_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866332
MHHNB11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69069
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18835
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852988
SUZ12	ENCODE Transcription Factor Targets	1.0	null
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23419
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83665
LLPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64776
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.835582
sirolimus_mus musculus_gpl7202_gse27784	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCP11L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63562
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74676
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
DASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
Perturb_8898_KD_IGF2BP1_SRP359044	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.21211
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Adult body size	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55049
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34896
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.294717
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89486
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166317_3_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31147
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.882702
first (dorsal) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37812
TTA-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.501
MTREX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1884
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00849
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.365633
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09334
Mesophyll cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
GSE61117_0_v_1_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.704
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983222
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09047
GTEx Nerve 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	11.3509
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
hsa-miR-497	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16223
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9243
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAMD14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22437
NCIH2066	CCLE Cell Line Gene CNV Profiles	1.0	1.59934
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60827
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825613
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36671
CPXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8771
Perturb_10767_KO_Nrf2_SRP311380	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.3329
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28543
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
Cellular bud neck septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.909
retinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.186811
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-345-NHLH2_NHLH2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO829	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73594
Septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.759
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6504_KD_PIEZO1_SRP140640	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.25361
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15027
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04172
Thyroid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.908
QF-45-KI95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.474639
disease	GWASdb SNP-Disease Associations	1.0	0.028718
Mitotic septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.592
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51946
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993251
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09342
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70821
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABCB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90157
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40605
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1701
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.35103
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970992
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1879
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62243
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08538
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.38824
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16929
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.987357
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10289
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858843
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.88072
Canavan disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mIMCD-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75372
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U343	CCLE Cell Line Gene Expression Profiles	1.0	1.75851
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01362
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06251
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58984
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BARHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90828
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCCSUP	CCLE Cell Line Gene CNV Profiles	1.0	1.42598
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14848
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41141
HS578T	CCLE Cell Line Gene Mutation Profiles	1.0	null
H4K20me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1181
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17418
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32192
JHH5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82085
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2604
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08263
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829538
intermediate stratum of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17735
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15979
ROGDI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28944
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9073
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129005
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00616
BOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83226
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HTh-74 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75008
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01544
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3596
Perturb_11171_KO_Tug1_SRP176442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.46549
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02727
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.379
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10428
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966351
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854266
GSE100464,GSE100465_0_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21057
Perturb_1292_KO_Krt17_SRP298760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.72846
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.15422
phosphorylation	GO Biological Process Annotations 2025	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2406
tegmental field of p3 (Forel's field)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23745
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.999695
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04152
USF1	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12659
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15392
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.41902
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37159
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4218
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95441
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60732
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837578
HSC39	DepMap CRISPR Gene Dependency	1.0	2.06643
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33828
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.97741
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32739
MLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86597
Perturb_2250_KO_Piezo1_SRP355856	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.4146
SNU175	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23919
hsa-miR-424	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186287_2_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31566
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21057
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5498
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08412
primary motor cortex (area M1, area 4)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15563
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69121
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36993
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27546
TMEM219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64757
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54587
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66175
capan2	HPA Cell Line Gene Expression Profiles	-1.0	-0.873889
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POYW-1126-SM-48TCI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826058
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846921
Exocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.054
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.21099
EN1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.031096
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12549
GSE248858_5_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82647
perimammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26346
NOL4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6795
Perturb_17802_KO_ZNF675_SRP305529	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.40645
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE249544,GSE249637_9_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52411
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33141
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PABPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93199
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056618
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17928
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51715
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982201
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0452
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45422
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17743
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEx Nerve 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	13.5061
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59513
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
second (ventral) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09862
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00929
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888416
MJ	CCLE Cell Line Gene Expression Profiles	1.0	1.60522
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27405
ACTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63136
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051942
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43238
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2551
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904952
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22374
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.889007
NOTCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61052
KDM4A	ENCODE Transcription Factor Targets	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.265038
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56646
KCIMOH1	CCLE Cell Line Gene CNV Profiles	1.0	1.37349
TBP	ENCODE Transcription Factor Targets	1.0	null
GALE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50989
ZNF540	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12236
SERF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51337
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85819
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284131
CLIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67258
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053845
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35283
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34184
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12778
L1236	CCLE Cell Line Gene Expression Profiles	1.0	1.68286
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65514
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07882
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919756
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.97576
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.391
ATP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56851
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935994
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01623
NO11	DepMap CRISPR Gene Dependency	1.0	3.06164
(7S)-2-(2-AMINOPYRIMIDIN-4-YL)-7-(2-FLUOROETHYL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE	DGIdb Drug Targets 2026	1.0	7.56171
LPS510	DepMap CRISPR Gene Dependency	1.0	3.8192
Perturb_14835_KD_Scr_SRP017110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00783
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-2355-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884934
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34009
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
c211	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50203
thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.581618
UCMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89114
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.8675
LAMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5948
ATF3	ENCODE Transcription Factor Targets	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.199356
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.43524
Perturb_17044_KD_IRF4_SRP201887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
P2RX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83389
medial (main) part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09577
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12312
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26939
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
JHOM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50846
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
LRRC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2123
H3K27me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14931
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05046
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1997
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.834046
Contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.307
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01774
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11927
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.72591
PMC4695334-mmc3.xls-MDA_SMAD3_DNA_Me-Unnamed_2_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
FAM118B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32706
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.98944
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876628
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.991931
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43065
GTEx Nerve 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	5.06464
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
MRPL49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16078
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49337
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25506
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.643
LRIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81322
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0411
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08827
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05658
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53546
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10488
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.4279
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5259
KDM5B	ENCODE Transcription Factor Targets	1.0	null
POU4F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62541
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61656
magnesium ion binding	GO Molecular Function Annotations 2023	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13843
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.922061
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.916921
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2389
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09145
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904905
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97958
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
Apical bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927243
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992637
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.681064
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SEC61A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63642
RNF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9765
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01623
Perturb_11318_KO_Nr1d1/Nr1d2_SRP241717	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.80709
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30269
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19706
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22175
Gin4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.909
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841961
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C3A	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62023
NRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66717
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.852836
DACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17767
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50962
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56836
GSE249544,GSE249637_9_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Papillary thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.769
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74619
Symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
inferior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824235
LMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65476
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.997593
Perturb_13133_KO_Pnpt1_SRP134850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.4507
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12529
Perturb_4683_KO_Mll2/Suz12_SRP189864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.74123
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO783	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32762
TMCO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46299
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84165
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.926998
REST_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.625732
phosphorylation	GO Biological Process Annotations 2023	1.0	null
REST_Panc1_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88007
EZH2	ENCODE Transcription Factor Targets	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942839
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879977
GSE205163,GSE205164_2_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40592
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28641
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06026
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973094
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08033
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.808
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28686
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61218
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31735
SOX10_KO_GDS3480_257_rat_Schwannoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cellular bud neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.68848
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MIGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4327
GSE75976_3_v_4_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.769083
Perturb_15063_OE_Trp53_SRP345823	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.2188
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27342
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21228
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858843
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872064
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858265
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.939589
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36083
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.46903
CMTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39448
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070706
TBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95161
ZNF286A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-0.82741
spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240276
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8845
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37022
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03013
E2F6	ENCODE Transcription Factor Targets	1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.36652
127399	DepMap CRISPR Gene Dependency	1.0	2.80595
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45744
FSCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83757
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53639
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62708
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7601
POP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30632
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59776
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17482
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02415
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47183
H2AC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52059
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28942
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5908
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89844
EIF4G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02295
22RV1	DepMap CRISPR Gene Dependency	1.0	2.13506
SMIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05241
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1922
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4047
ACSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47254
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86808
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17923
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.790435
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67041
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51768
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55628
IRF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30023
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32819
GNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93607
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02101
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844112
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17296_KO_Sox8/Sox9_ERP014609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827694
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34509
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.98968
DCAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79058
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0657
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.884641
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98549
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42547
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32319
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05318
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69586
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
layer 1 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76908
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5464
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01289
k1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.535
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.661929
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3554
Trophectoderm cell_Embryo_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-WHWD-0826-SM-3LK6R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991947
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12429
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13987
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.294053
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07254
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.965739
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38316
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22139
HEC1B	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13212
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_Panc1_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839211
CRABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06047
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83573
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
OGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76851
TPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86611
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896155
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6181
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70328
mRNA_ETV3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08995
SP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.89343
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01652
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29654
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72391
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.16884
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53998
metal ion binding	GO Molecular Function Annotations 2023	1.0	null
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11817
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6484
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06525
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60027
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9755
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8366
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88933
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870549
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76577
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYP20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96382
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836124
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2597
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03639
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.8675
H3K4me1_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6771
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7511
Perturb_5527_OE_Uprt_ERP106180	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.61148
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19886
JOSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00043
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05111
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1254
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.973046
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15648
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46564
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.238752
non-growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.047
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88885
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10525
SNU81	CCLE Cell Line Gene Mutation Profiles	1.0	null
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13431
preoptic telencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27322
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22331
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
OCUBM	DepMap CRISPR Gene Dependency	1.0	3.12601
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980198
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8718
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77026
TSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22166
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39335
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
KCTD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68408
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933321
GP2D	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64084
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20288
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1667
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865661
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053053
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987966
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57763
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833701
ZNF217	ENCODE Transcription Factor Targets	1.0	null
Perturb_11976_KO_Dhcr24_SRP251850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.59543
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	3.40802
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.90494
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21015
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE246461,GSE246463_5_v_0_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.89709
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PTPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8012
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30775
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057295
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17556
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402523
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
PIWIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04908
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ONECUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38701
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04826
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73386
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-w_SRPK2-KD-kinase_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.634021
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 6 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10137
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88899
A172	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55951
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19923
UGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98975
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09999
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sporulating cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6747
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.93276
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3684
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17256
ARL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81051
intermediate stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61837
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06511
GSE188884,GSE189078_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
697	DepMap CRISPR Gene Dependency	1.0	2.48326
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9414
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21848
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18964
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83871
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.633549
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62149
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11938
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83647
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.902021
reticular formation of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17735
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84918
RDH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67712
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09577
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0513
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09019
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36608
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00832
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.50403
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898796
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8048
NCIH1869	CCLE Cell Line Gene CNV Profiles	1.0	2.18002
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052863
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27371
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56113
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65801
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.08437
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01381
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25832
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18538
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211286_7_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36837
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839071
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21142
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07014
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.39297
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32988
WDR81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3039
MKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51677
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17482
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67989
NCIH661	CCLE Cell Line Gene CNV Profiles	1.0	1.42464
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99208
thyroid carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.61162
mantle zone of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26293
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29349
GSS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3973
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22615
laminin-11 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9423
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931365
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37026
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16241
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE208435_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83516
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866446
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19427
intermediate periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61901
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Polarisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCEAL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51415
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03015
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20542
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UTP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25922
GFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21385
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33156
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35934
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04599
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37868
H3K27me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31585
FTC-133 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44557
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12066
RFX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48754
RBM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28695
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05032
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00264
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951833
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14937
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.48798
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48744
Perturb_13048_KO_Il33_SRP259135	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71921
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41269
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU182	CCLE Cell Line Gene CNV Profiles	1.0	1.34314
PMC11799605-jomes-34-1-65-supple.pdf-11-KLF16_KLF16	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878219
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
lateral SC part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14083
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03511
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23381
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99385
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.920509
Gemmule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35389
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
magnesium ion binding	GO Molecular Function Annotations 2025	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33715
HEC108	CCLE Cell Line Gene Mutation Profiles	1.0	null
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34635
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866583
VN1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73002
Mitotic spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37129
thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.74883
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15671
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17482
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8739
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28606
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828931
BB-41-XE67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318469
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27565
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67739
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90734
B-CPAP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.617
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982397
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GSDMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17401
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.051665
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.36237
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843166
intergeniculate leaflet	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13234
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831118
SNU1	CCLE Cell Line Gene Mutation Profiles	1.0	null
papillary adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.24732
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02817
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926435
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264011
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933021
septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.08526
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.603626
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40117
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5302
GSE139966_1_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
Teratoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
transferase activity, transferring phosphorus-containing groups	GO Molecular Function Annotations 2015	1.0	null
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82857
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84878
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09862
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064204
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.08884
HDAC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71467
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21024
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26942
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF500	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88737
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAP3K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22324
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19848
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13093
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87474
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93312
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44659
TB-06-VB30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276822
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44283
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.36047
HPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7006
COQ9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00029
STRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08574
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83252
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80152
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
npa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.43292
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9375
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6947
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943177
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52441
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85093
SMAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.62336
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26939
BX-912	LINCS KinomeScan Kinase Inhibitor Targets	1.0	1.36211
Perturb_8389_KO_Rnaseh1_SRP108593	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.87774
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918507
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.393936
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94671
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
SFXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
ASPHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71673
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6965
HNRNPUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08154
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.63782
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56948
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03744
HUWE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06203
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06475
NMRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09183
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102518
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83297
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35505
Medial cortical node	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95013
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0701
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17671
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953631
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57209
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43894
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904905
MM160113	DepMap CRISPR Gene Dependency	1.0	4.47751
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07787
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66937
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846296
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61899
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15794
microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.105894
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05378
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3511
ATOH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25892
Perturb_15807_KO_Chop_SRP350242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19484
PF382	CCLE Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58158
TAF1	ENCODE Transcription Factor Targets	1.0	null
IGROV1	DepMap CRISPR Gene Dependency	1.0	5.65574
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6853299-pbio.3000476.s011.xlsx-Fig_4A-RA_812_genes_expression_ratio_in_ZF_and_OF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2478
DNAJB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62685
HOXB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46379
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45411
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69484
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.940146
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02233
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.932725
FES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86586
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cortical actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.218
Perturb_15117_KD_Rtn4_SRP278924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.36801
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13101
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17528_KD_MEOX1_SRP213607	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.59931
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45058
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933321
32D cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4519
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48773
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91819
GSE157594_6_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12115
isthmic part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1479
ZNF691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41496
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JAGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69426
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.53475
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	13.1336
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42607
CEBPB_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26992
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9686
BBS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63317
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50079
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.864
Cell division site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.202
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40519
KYSE520	DepMap CRISPR Gene Dependency	1.0	7.80598
MTERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07512
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55311
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67642
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898675
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04533
MZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37816
biological_process	GO Biological Process Annotations 2015	1.0	null
KP2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65861
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14588
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966143
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55642
ME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83721
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3485
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46477
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909539
MANEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62891
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882858
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843166
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.603
CPNE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60217
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62768
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.89143
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.861441
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51808
PMC12629863-CAC2-45-1547-s002.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Kinases_predicted_to_phosphorylat_YY1_at_Ser247_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02467
septin collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.44912
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69445
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
HGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71978
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00224
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.29586
hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.279724
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08159
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27842
Mitotic actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.989
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_2005_KO_Msi2_SRP201799	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.43142
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826279
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MED11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38016
ZC3H12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26965
SNU1076	DepMap CRISPR Gene Dependency	1.0	2.0733
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42536
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07198
Medial preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68867
Perturb_2011_KO_Cd40lg_ERP130522	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.7659
lung	HPA Tissue Gene Expression Profiles	1.0	0.890082
ZNF665	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58943
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834538
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61738
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16427
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01513
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.71468
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88438
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57402
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94296
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268482
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47658
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928682
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1464
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289582
thp1	HPA Cell Line Gene Expression Profiles	1.0	0.890813
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.456828
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922278
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849494
TRIM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45218
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28878
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78617
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22468
GSE173873_10_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03087
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36188
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72051
TMEM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75062
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.864347
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35516
Spondylometaphyseal dysplasia Sedaghatian type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.2754
EDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40896
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41769
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992783
MAZ	ENCODE Transcription Factor Targets	1.0	null
protein serine/threonine kinase activity	GO Molecular Function Annotations 2025	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6619
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81204
GNG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75634
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31177
retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.186811
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057057
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
MYC	ENCODE Transcription Factor Targets	1.0	null
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.80288
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cdc42 GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.903
PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Up_REST	Rummagene Transcription Factor Associations 2026	1.0	null
TPD52L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06997
oaw42	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.45471
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.943757
Papillary thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
PACSIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76371
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30605
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
PLAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0719
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25211
COLO741	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74574
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45248
intermediate stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04826
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81683
SEPTIN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31886
Nthy-ori 3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.626
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02758
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11238
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79392
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985995
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02644
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein serine/threonine kinase activity	GO Molecular Function Annotations 2015	1.0	null
preoptic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26939
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20399
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61035
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27723
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42862
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4445
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28641
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FXYD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27057
FAM171B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38803
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1112
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991175
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10191
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LCLC103H	CCLE Cell Line Gene CNV Profiles	1.0	1.51373
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.943341
NCIH2171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.78723
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.289027
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AGMAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66048
septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.62295
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HMGN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08615
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54903
CIDEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46264
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38046
hsa-miR-16	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29086
LTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91972
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40453
HS616T	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phosphotransferase activity, alcohol group as acceptor	GO Molecular Function Annotations 2015	1.0	null
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42314
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933321
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0488
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03763
cellular bud	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.58507
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85818
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.329
GSE125403_7_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99208
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966351
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06464
ERGIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75805
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23433
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30439
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2656
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52351
GSE249544,GSE249637_9_v_2_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
PCDHB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2615
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995013
PC3	DepMap CRISPR Gene Dependency	1.0	2.02773
KLHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32458
ELL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40135
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985259
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47843
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850932
Thyroid adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
rhombomere 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22243
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72712
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30071
r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04826
Nodular goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126652
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930803
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40578
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957374
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08071
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947096
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septin band	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.98692
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99641
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.92171
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
QRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34554
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
phosphate-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070635
S117	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82763
GSE132408_0_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
rectum	HPA Tissue Protein Expression Profiles	-1.0	-0.987357
mantle zone of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09577
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907246
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849375
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23124
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975114
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30721
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33623
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87654
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08048
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71708
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SEPTIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44267
RCC10RGB	CCLE Cell Line Gene Mutation Profiles	1.0	null
NCIH23	CCLE Cell Line Gene CNV Profiles	1.0	1.42579
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935794
GSE225083_0_v_1_kras_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44659
ZNF391	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25487
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01556
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43944
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986373
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49996
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76884
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14352
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE249544,GSE249637_9_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.183248
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14322
URB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.061
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01289
TTLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03314
GNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99301
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6292
TMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74786
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03857
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31659
LB771HNC	DepMap CRISPR Gene Dependency	1.0	2.54963
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20969
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074331
Spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11127
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41419
EHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14153
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133047
TDRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69043
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922679
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28542
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0128
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29498
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4061
Medial geniculate complex, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26819
Endocytic patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
NCIH1793	CCLE Cell Line Gene Expression Profiles	1.0	1.46365
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11452
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48753
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	2.04549
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11302
PSMB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07909
HDAC2	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.860787
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56723
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927794
BHY	CCLE Cell Line Gene CNV Profiles	1.0	1.95997
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SNX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86638
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60455
endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.501909
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14115
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11937
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71059
magnesium ion binding	GO Molecular Function Annotations 2015	1.0	null
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84577
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72382
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.837882
cellular process	GO Biological Process Annotations 2015	1.0	null
RWDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79322
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83079
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917713
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909614
PFKFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62546
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2527
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8616
REST_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4822
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66191
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68067
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
periventricular stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19596
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94915
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.86837
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94482
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1005
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958536
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57073
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828993
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84789
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35708
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915057
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929465
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00141
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16884
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14913
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03889
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-LUAD_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
site of polarized growth	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.892556
ftc238	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848457
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33556
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836426
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05633
HTC-C3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.574
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4965
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
OAW42	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15202
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
DPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54616
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79479
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05032
GSE142684_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30379
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66778
ABCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73351
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KAT2B	ENCODE Transcription Factor Targets	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.89143
DNAJC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71075
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052031
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928981
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68259
OVISE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39282
IBTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38927
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5353
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48796
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.0014
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MAP3K11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94336
NCIH2172	CCLE Cell Line Gene CNV Profiles	1.0	1.57385
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80697
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23235
protein modification process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63292
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067131
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23017
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TPBGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26607
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2333
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053922
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71818
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
SAMD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59913
PPP1R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19082
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16244
YY1AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11286
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.85966
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21399
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
TRIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52194
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Achene	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59208
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42417
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891761
CMTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67179
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888264
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07574
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16012
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85766
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75934
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70848
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57781
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06603
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45927
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39625
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
IMR32	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40925
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34849
PPP1R14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Plant collar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79554
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13886
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097167
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88985
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21543
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19323
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55927
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916948
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42645
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12826
GTEx Skin 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-5.9422
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
U251MG	CCLE Cell Line Gene Expression Profiles	1.0	1.47192
SCRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37109
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43447
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21806
PLD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94431
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.872117
papillary thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1235
HDAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58233
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52072
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.40328
Actin cortical patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.78
DVL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44855
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27255
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9675
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	2.20297
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1631
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
papillary thyroid carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.889668
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10624
spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.391615
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21722
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33845
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
496100425_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45884
Posterior parietal association areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30787
PCDHB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76513
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942324
Hypodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
GTEX-OXRN-1426-SM-3LK5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0914
NCIH2106	CCLE Cell Line Gene Expression Profiles	1.0	1.90892
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85513
ntera2	HPA Cell Line Gene Expression Profiles	-1.0	-0.888346
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70242
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.677826
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909961
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCHACV	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21369
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
C8166	DepMap CRISPR Gene Dependency	1.0	3.17919
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39229
bj	HPA Cell Line Gene Expression Profiles	1.0	0.853211
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918709
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30316
CHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63885
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83059
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74304
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96072
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64516
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61035
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825112
REST_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15692
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89691
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92718
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16376
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1607
NCIH1568	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11821
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
ADAM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08641
NCIH2172	CCLE Cell Line Gene Mutation Profiles	1.0	null
ZNF518A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01442
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
NCCSTCK140	CCLE Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933321
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00187
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25239
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.922963
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04609
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80219
thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.30208
PMC10140619-mmc5.xlsx-Beta3_ConVsBSL-Gene_BHLHE22	Rummagene Transcription Factor Associations 2026	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.92939
Protein kinase domain	InterPro Predicted Protein Domain Annotations	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.867929
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.904745
ZNF268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89094
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872064
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865877
Periventricular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15565
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12596
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0346
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00829
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cellular bud	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.689
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55647
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Head capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
MSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82639
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.955724
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.36643
Perturb_1296_KO_Krt17_SRP298760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.64042
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895633
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-x_LPS-BMDCs-kinase_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1648
CIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09977
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.926162
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76409
CEBPB_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55348
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05564
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.978577
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.773
GSE139948_3_v_2_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RPL36AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18353
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25614
PAX5	ENCODE Transcription Factor Targets	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3443
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16225
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32958
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859672
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
ZC3H12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.782
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.935088
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2165_KO_Prmt1_SRP183800	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.65781
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CYP2R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41454
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5376
UOK101	DepMap CRISPR Gene Dependency	1.0	2.72235
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67397
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40205
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914797
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45636
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2258
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25866
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05032
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891005
ELF1	ENCODE Transcription Factor Targets	1.0	null
lung cancer	GWASdb SNP-Disease Associations	1.0	0.335431
NFYB	ENCODE Transcription Factor Targets	1.0	null
DD-49-YG96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.8675
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906974
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MKN45	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59267
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0387
NCIH196	CCLE Cell Line Gene CNV Profiles	1.0	1.35682
Thyroid gland follicular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myelin sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PCMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51827
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09425
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54598
GSE157233_2_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25554
preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32797
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Follicular thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.36161
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845252
Papillary adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
CAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61859
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18099
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48473
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.489
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09215
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918778
Serine/threonine-protein kinase, active site	InterPro Predicted Protein Domain Annotations	1.0	null
GSE180468_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55587
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21184
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27553
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35983
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08519
ZNF843	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1833
FGF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09394
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46486
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF396	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75907
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94475
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13672
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42948
Perturb_2229_KO_Rela_ERP122918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.6348
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.889952
TXNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36776
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22938
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999358
Distal myopathy with anterior tibial onset	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.86
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7305
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16524
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6438
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45229
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ACSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89805
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90801
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.80155
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1702
GSE248858_1_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00981
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16034
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940175
SUDHL10	DepMap CRISPR Gene Dependency	1.0	3.16096
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02831
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.30616
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS852T	CCLE Cell Line Gene Expression Profiles	1.0	2.37999
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60232
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HDGFL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45667
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09505
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80275
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08863
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845004
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IMPDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84758
NPTXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2339
cd92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6066
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876428
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5177
MEWO	CCLE Cell Line Gene Mutation Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4565
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.1788
OCILY3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61454
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76214
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4134
HCT116	CCLE Cell Line Gene Mutation Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052246
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79613
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842241
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28816
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0089
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11552
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.83097
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53416
PMC10140619-mmc5.xlsx-Rank_Beta1-Beta3-Gene_BHLHE22	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00542
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.627081
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4582
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2024
ADAM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14073
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99375
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47145
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315135
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10641
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17577
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07157
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917694
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.08746
MSRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16029
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.911285
Perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.616
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01482
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.981839
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58334
HEY	DepMap CRISPR Gene Dependency	1.0	3.72844
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27763
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cellular bud neck contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
SW48	CCLE Cell Line Gene Mutation Profiles	1.0	null
SSNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18739
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964908
TRAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84295
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946105
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90736
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.332
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68173
LN235	CCLE Cell Line Gene Expression Profiles	1.0	1.3732
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33918
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08654
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41262
FLT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12507
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.98944
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4329
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24869
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858291
HMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57361
MRFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FU97	DepMap CRISPR Gene Dependency	1.0	2.60613
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPCN	CCLE Cell Line Gene Expression Profiles	1.0	1.55917
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984491
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81402
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0356
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0557
Thyroid gland anaplastic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943321
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16073
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78901
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12616
withdrawal disorder	GWASdb SNP-Disease Associations	1.0	0.898875
496100334_PCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11358
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33113
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.8177
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918709
Medial geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12954
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.58387
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03572
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94064
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913982
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65475
GSE217378_1_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38136
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP binding	GO Molecular Function Annotations 2023	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850851
Perturb_17806_KO_ZNF675_SRP304971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.40645
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63467
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213632_1_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18139
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154069_2_v_4_satb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11025
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38637
SLC7A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15065
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	2.24804
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF280A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5061
CCT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49091
KCNK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95026
RBBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65949
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50629
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969256
protein phosphorylation	GO Biological Process Annotations 2025	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6826
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20907
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29956
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05461
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843275
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13502
CAKI1	DepMap CRISPR Gene Dependency	1.0	3.05104
L428	CCLE Cell Line Gene Expression Profiles	1.0	1.84085
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.98944
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04604
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907246
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0138
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.71606
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08625
germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.57008
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.97233
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55372
Septin collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.264
GDM1	CCLE Cell Line Gene Mutation Profiles	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08972
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.07503
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74046
DUSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78949
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81752
GRAMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66803
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57896
TF-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.831508
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915357
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C2orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9282
Perturb_11301_KO_Nr1d1/Nr1d2_SRP241717	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.95955
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941186
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2342	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045506
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.70962
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41177
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9929
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76784
AMFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93165
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22694
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841903
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57433
Nrd1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.366
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48574
PSMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61534
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63438
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
Lateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55088
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21011
GTEX-TKQ1-0326-SM-4DXSM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835011
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869962
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.901638
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839055
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1345
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07276
RELA_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69375
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF724	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67497
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02685
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56256
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07092
KYSE70	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81602
protein kinase activity	GO Molecular Function Annotations 2015	1.0	null
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29368
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.351
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878667
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.851407
REST_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955047
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.8675
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84697
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28149
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.987357
Perturb_4143_KO_Bcl11a_SRP334609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.60945
WRO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
JUND_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89928
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
SNRK_overexpression_127_GSE30185	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.60684
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93669
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16391
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19835
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64051
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14655
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03398
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08025
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09409
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.90321
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26763
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88138
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03662
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06491
Megasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13426
Plasmodesma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
ADAM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24819
ESR1-20056654-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
km3	HPA Cell Line Gene Expression Profiles	-1.0	-0.859495
ZNF281	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42152
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9034
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24694
TRAPPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17918
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911308
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2099
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99684
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cuneus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.986169
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72323
Multiple synapse bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
Perturb_11213_OE_arcA_SRP351667	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.20398
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861328
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21441
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RL952	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88199
GSE239578_2_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GRANTA519	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874073
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.89011
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31543
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11284
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6444
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
STAT3	ENCODE Transcription Factor Targets	1.0	null
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67286
Vegetative stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841106
SLC25A28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36692
layer 2 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36965
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0715
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70328
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50323
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37507
NUF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43648
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19126
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51541
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31846
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49783
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	2.18995
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	8.87246
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
erythroleukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.492572
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3889
SNU308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66567
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917659
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892564
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70287
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	1.0	0.8675
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10624
GSE111247_11_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
retrosplenial cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10595
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924459
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.107412
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78188
DHCR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31981
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14972
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12115
PRR15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24883
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6159
OVCA-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
PLCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67041
PPP1R15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37268
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61343
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51274
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71858
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03521
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44521
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55022
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39658
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
COV644	DepMap CRISPR Gene Dependency	1.0	3.47798
SUPM2	CCLE Cell Line Gene Mutation Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35077
retinal cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.186811
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05848
lung carcinoma	GWASdb SNP-Disease Associations	1.0	0.386101
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23289
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TDG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49276
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886137
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4111
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18048
hsa-miR-15b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27342
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80027
HEC1A	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65947
Perturb_8982_OE_MEOX2_SRP362177	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.86768
Cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.865
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68694
REST_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1632
adenyl ribonucleotide binding	GO Molecular Function Annotations 2023	1.0	null
anion binding	GO Molecular Function Annotations 2015	1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1038
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89909
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.926756
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.357086
EGR1	ENCODE Transcription Factor Targets	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64729
B4GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74072
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03675
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23487
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960282
E2F4	ENCODE Transcription Factor Targets	1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3533_OE_HLAG_SRP386253	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54227
UOK101	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5125
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863915
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29223
DOV13	DepMap CRISPR Gene Dependency	1.0	7.80897
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2961
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47754
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.852836
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31936
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18198
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44342
Perturb_5043_KO_Adnp_SRP313259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.6704
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858843
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851437
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70377
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911781
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29609
RBM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84485
separase-securin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861806
PGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34542
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00186
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49104
ZNF143	ENCODE Transcription Factor Targets	1.0	null
NGLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25478
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.304718
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848125
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55927
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2564
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14884
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38696
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35053
ENPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26821
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33124
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.25853
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33183
CPEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78045
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053278
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147669_2_v_1_tram2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1223
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041338
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58036
PCCL-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.794
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68426
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6548
mantle zone of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37398
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66705
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-1926-SM-3K2AR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05771
FKBP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8555
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48132
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62147
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37812
CMTM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67707
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08364
CREBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5563
KAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1603
ZNF320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88534
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4008
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.29586
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12549544-mmc2.xlsx-AA_D28_VS_D42-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86834
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48372
Cellular bud neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.703
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04953
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78285
LUC7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39472
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56772
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67244
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8171
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36675
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23577
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06531
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02049
SOX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94505
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825919
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21681
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05122
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.956252
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01362
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394197
NCIH1339	CCLE Cell Line Gene Expression Profiles	1.0	1.40596
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20365
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-BRCA_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
PCNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43415
RAB6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3418
CRABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89782
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34666
Perturb_4651_KO_Tip55_SRP134924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.47894
ZNF668	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85367
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55628
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKPNDW	DepMap CRISPR Gene Dependency	1.0	3.09669
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.03129
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16912
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960679
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20023
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61818
OTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12773
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88222
LOUCY	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74847
PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12498101-cd-24-1904_supplementary_tables_s1-s12_suppst1.xlsx-S7-Supplementary_Table_7_Human_tissue_RNA-seq_differential_analysis_for_SPOPmut_vs_SPOPwt_AA_vs_AG_and_AG_vs_GG_clone_data_DEG_set_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72842
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13549
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2238
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-1026-SM-4AT4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924295
protein serine/threonine kinase activity	GO Molecular Function Annotations 2023	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-1.00972
Perturb_765_KD_ZFR_SRP107875	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.53897
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33233
BCCIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90296
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967245
phosphorylation	GO Biological Process Annotations 2015	1.0	null
SMG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12404
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04897
septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.59026
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058752
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51946
ZNF449	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99048
cell cortex part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.737813
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063276
Charcot-Marie-Tooth disease type 2Y	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11593
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44746
SURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41019
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.683
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.906697
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216325
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.943757
bone marrow cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.419623
CUX1	ENCODE Transcription Factor Targets	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35997
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.041463
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11234
Perturb_7991_KO_Dnmt3a_ERP107945	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.29051
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0834
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.61564
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
KP1N	CCLE Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.922825
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90213
JDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18501
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048523
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0298
IPMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28509
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843166
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	2.13759
calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.24715
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054298
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41423
ATP13A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12512
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23855
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.309705
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14701
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03627
Perturb_8388_KO_Rnaseh1_SRP108593	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.02386
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883459
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54187
TMSB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94139
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60399
GLC82	CCLE Cell Line Gene CNV Profiles	1.0	2.43125
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.243519
NFE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27157
RARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0512
GSE191138_2_v_4_fmo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.031046
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.8675
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5279
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59013
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.044214
Perturb_15983_KO_Larp7_SRP189392	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.18573
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44205
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04671
GSE155800_1_v_0_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36777
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.20929
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
LC-42-WU67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201586
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.293151
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08544
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79216
ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.183541
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64849
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904842
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0112
NCIH2110	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10571
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883116
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31421
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843166
GSE233112_2_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935658
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC15	DepMap CRISPR Gene Dependency	1.0	4.59478
ALG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44918
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20531
SEM	DepMap CRISPR Gene Dependency	1.0	2.4744
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.0169
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27641
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858886
ZNF232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31258
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03116
PMC6853299-pbio.3000476.s011.xlsx-Fig_4A-HVC_612_gene_expression_ratio_in_ZF_and_OF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24832
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3679
CTBP2	ENCODE Transcription Factor Targets	1.0	null
U87MG	CCLE Cell Line Gene Expression Profiles	1.0	1.35637
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2023	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0327
Thyroid gland carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
GTEX-P4QS-0626-SM-3NMD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830142
C80	DepMap CRISPR Gene Dependency	1.0	6.67913
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.3212
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1337
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BGC823	CCLE Cell Line Gene CNV Profiles	1.0	1.84429
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37442
HDQP1	CCLE Cell Line Gene CNV Profiles	1.0	1.50855
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28368
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6168
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TUBA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4928
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50343
SIHA	CCLE Cell Line Gene CNV Profiles	1.0	1.81135
RAB31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74313
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_6503_KD_PIEZO1_SRP140640	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.59357
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51375
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10322
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4476
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933321
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83302
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.8675
OV7	DepMap CRISPR Gene Dependency	1.0	3.25675
Thyroid gland adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
kinase activity	GO Molecular Function Annotations 2015	1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ROMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06257
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19285
BT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHKG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4401
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.051535
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
adenyl ribonucleotide binding	GO Molecular Function Annotations 2025	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1426
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25889
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58543
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03646
BACH1	ENCODE Transcription Factor Targets	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3868
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.926162
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57439
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30608
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12314
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03572
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29147
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61111
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16791
Joubert syndrome 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.052
IGROV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
NTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79227
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.997152
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20229
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4941
CASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09465
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS852T	CCLE Cell Line Gene CNV Profiles	1.0	2.15823
CMLT1	CCLE Cell Line Gene Mutation Profiles	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883827
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4044
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29342
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60652
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58
ZNF446	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6404
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73577
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32403
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20298
EN	DepMap CRISPR Gene Dependency	1.0	2.24792
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34599
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24322
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10658
Leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96317
LATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46782
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06623
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55415
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29324
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.973902
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54513
Protein kinase-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8271
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34493
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16545
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.970363
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041137
Thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.649
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NPA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.72
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975648
REST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84617
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105616
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63797
CEBPB_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30191
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
L363	CCLE Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06653
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857756
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76613
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05032
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02103
RAD21	ENCODE Transcription Factor Targets	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18113
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32204
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66598
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04788
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68862
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13509
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953442
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01707
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
GSE173873_8_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99942
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01289
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995016
KLF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10532
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.581521
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75065
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ASCL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82826
KCTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0813
MTA3	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01193
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
inclusion body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.126244
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924654
WM88	DepMap CRISPR Gene Dependency	1.0	2.37583
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86595
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.99819
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68608
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-195	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866583
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8058
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF639	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01076
Hydrogenosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.132
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-Embryo-Hatchling_1272_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKMEL24	CCLE Cell Line Gene Expression Profiles	1.0	1.65294
GSE203158_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47465
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.31469
tf-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721166
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41262
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22959
HCC1359	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78233
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
Laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.545
CDK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79561
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76925
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20553
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-w_SRPK2-KD-mouse_kinase_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07205
TP53INP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4926
YIPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82207
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12297
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35854
NCIH1623	CCLE Cell Line Gene Mutation Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.943815
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05825
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6939
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825112
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4838
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46466
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45925
Serine/threonine/dual specificity protein kinase, catalytic  domain	InterPro Predicted Protein Domain Annotations	1.0	null
MLLT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09952
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50874
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIR34_OE_GDS2755_645_human_HCT116 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36675
mp9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
DCHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45654